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170 Years Of San Francisco Sea Level Pressure, Brendan Heaven Jan 2025

170 Years Of San Francisco Sea Level Pressure, Brendan Heaven

Theses

This data-recovery project and subsequent data analyses address the construction of a continuous, long instrumental record of sea level pressure for San Francisco, California, USA and examines what the time series may reveal about atmospheric patterns through time. Atmospheric pressure is a physical component which is associated with both daily and seasonal weather phenomena and is one of the most robust of the meteorological variables. Observational data of surface pressure (SFP) and later sea level pressure (SLP) were accessed from digital archives, with a large part of these being manually keyed from original observations on paper. San Francisco, being near …

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Expression, Purification, And Characterization Of The Angiopoietin-Like 4 Protein N-Terminus, Alexis Leann Paskach Jan 2025

Expression, Purification, And Characterization Of The Angiopoietin-Like 4 Protein N-Terminus, Alexis Leann Paskach

Theses

This research focused on developing protocols to express and purify the N-terminus of angiopoietin-like protein 4 (nANGPTL4), and identify its structural characteristics to understand its possible contribution to cancer metastasis. Bacteria expression was optimized by adding magnesium, calcium, and glycerol to the initial Luria-Bertani (LB) broth incubation, then transferring to Terrific Broth (TB) for induction. Purification was enhanced through overnight nickel resin suspension, extended sonification, and buffer adjustments. Protein recovery was further improved by transferring size exclusion columns to G50 superfine resin. Protein purity was analyzed using SDS-PAGE and native gel electrophoresis, while protein content was determined through UV-Vis spectroscopy. …

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Deep Learning Time Series Prediction Strategies For Efficiently Emulating Noah Land Surface Model Soil Moisture Dynamics, Mitchell T. Dodson Jan 2025

Deep Learning Time Series Prediction Strategies For Efficiently Emulating Noah Land Surface Model Soil Moisture Dynamics, Mitchell T. Dodson

Theses

This work examines the ability of deep learning time series generative models to accurately and efficiently emulate the hourly temporal dynamics of the Noah Land Surface Model (Noah-LSM) out to a 2 week forecast horizon, given atmospheric forcings and static parameterization provided by the second phase North American Land Data Assimilation System (NLDAS-2) framework. Results from multiple neural network architectures are compared alongside variations in prediction target, loss function characteristics, and model properties. The most performant model types are subsequently evaluated with respect to forecast distance, annual seasonality, and against a variety of regional scenarios, including several event case studies. …

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Unbound Subgenres : Overlapping Age Categories In Contemporary Romance And Their Implications, London Stevenson Jan 2025

Unbound Subgenres : Overlapping Age Categories In Contemporary Romance And Their Implications, London Stevenson

Theses

This thesis aims to highlight the importance of genre labelling in contemporary romance fiction and the larger implications that come from the misuse of labels. Considerations of the genre based on narrative elements (Regis, 2003; Michelson, 2022), age categorization (Cart, 2011; Tribunella, 2007), and emerging market conditions (McAlister, 2018; Stewart, 2013) have generated considerable discussion over the last twenty-five years. While each of these scholars draws important conclusions about romance and its subgenres, none of them consider the significance of reader opinion, which is now enhanced due to literary digital spaces. In this paper, I examine nine romance novels for …

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Optimizing Reliability And Design Efficiency Of Liquid Rocket Engines : A Structural Margin Approach For The Early Design Lifecycle, Mason Tudor Jan 2025

Optimizing Reliability And Design Efficiency Of Liquid Rocket Engines : A Structural Margin Approach For The Early Design Lifecycle, Mason Tudor

Theses

This thesis introduces a reliability-based design methodology aimed at mitigating costs incurred during the Test-Fail-Fix cycle for Liquid Rocket Engines (LREs) by addressing the limitations of the standard Factor of Safety (FoS) approach. By integrating a neural network informed by a structural model into a Bayesian framework for uncertainty quantification, the methodology enables the characterization of structural margin and early analysis of failure risks in the design lifecycle. A generalized 3D component geometry is subjected to typical LRE loading environments within Finite Element Analysis software to gather data for stress and strength distributions. These distributions serve as a foundation for …

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Substance Misuse And Suicidal Behaviors In An Lgbtqia+ Sample: Examining The Buffering Effects Of Psychological Flexibility And Emotional Regulation, Mariano Ottone Jan 2025

Substance Misuse And Suicidal Behaviors In An Lgbtqia+ Sample: Examining The Buffering Effects Of Psychological Flexibility And Emotional Regulation, Mariano Ottone

College of Graduate Studies: Theses & Dissertations

Suicidal behaviors among LGBTQIA+ individuals, particularly in the context of substance misuse, present a significant area of exploration for mental health research and intervention. It is particularly important to evaluate factors capable of moderating this relationship, to promote more culturally affirming prevention models. This study aimed to explore the moderating roles of emotion regulation (ER) and psychological flexibility in the relationship between substance misuse and suicidal behaviors within the LGBTQIA+ community. Data were collected from 537 LGBTQIA+ adults through an online survey platform. Participants were asked to self-report on measures assessing the constructs of interest. The analysis focused on understanding …

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How Does Psychopathology Impact The Trajectory From State To Trait Mindfulness?, Veronica O'Brien Jan 2025

How Does Psychopathology Impact The Trajectory From State To Trait Mindfulness?, Veronica O'Brien

College of Graduate Studies: Theses & Dissertations

Previous research has found that higher levels of trait mindfulness protect against psychopathology (e.g., Chiesa & Serretti, 2013; Desrosiers et al., 2013; Sevilla-Llewellyn-Jones et al., 2018); however, the research on state mindfulness and psychopathology is more mixed. These mixed findings suggest that some clients with higher levels of psychopathology may have greater difficulty engaging with mindfulness practice thereby hampering their progression towards trait mindfulness and its associated benefits. The present study sought to explore how psychopathology (i.e., anxiety, trauma, alcohol use, and depression) relates to the growth of state and trait mindfulness. The present study recruited 274 participants from a …

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Perceived Credibility Of Allegations Of Sexual Assault Across Victim Race And Mental Health History, Liyah C. Morgan Jan 2025

Perceived Credibility Of Allegations Of Sexual Assault Across Victim Race And Mental Health History, Liyah C. Morgan

College of Graduate Studies: Theses & Dissertations

Previous research examined the effect of victim gender and rape myth acceptance (RMA) on perceptions of victim credibility; however, little attention has been given to the impact of victim race and mental health history, and even fewer studies have explored the intersection of these two identities. The primary purpose of the current study was to identify factors affecting understanding of perceived credibility of victims of sexual assault, specifically in terms of victim race and mental health history. The study also examined the role of RMA on perceptions of credibility and explored participant attitudes related to color-blind racial attitudes and mental …

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South Asian American Experiences Of Microaggressions And Wellbeing: The Moderating Role Of Social Support, Archita Birla Jan 2025

South Asian American Experiences Of Microaggressions And Wellbeing: The Moderating Role Of Social Support, Archita Birla

College of Graduate Studies: Theses & Dissertations

Although the South Asian American community is rapidly expanding in the United States (South Asian Americans Leading Together [SAALT], 2015), there remains a dearth of psychological research regarding the impacts on mental health and wellbeing affecting this diverse community. Racial microaggressions, or verbal or behavioral actions indicating hostile or negative attitudes toward marginalized individuals (Sue et al., 2007), negatively impact People of Color (POC) mental health and wellbeing (Forrest-Bank & Jenson, 2015a; Nadal, Wong, et al., 2015). Some research exists on South Asian American communities and microaggressions (Houshmand et al., 2014; Poolokasingham et al., 2014) but there is limited research …

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Resilience And Grit In Children And Adolescents With Autism Spectrum Disorder, Danielle Oehring Jan 2025

Resilience And Grit In Children And Adolescents With Autism Spectrum Disorder, Danielle Oehring

College of Graduate Studies: Theses & Dissertations

Resilience is the way in which an individual positively adapts to challenging or difficult life experiences. This process is marked by adjustments to external and internal demands through mental, emotional, and behavioral flexibility. Grit is perseverance and passion for long-term goals. Although grit and resilience have been researched in children and adolescents, there is a gap in the literature for how these variables relate to developmental disorders, like autism spectrum disorder, in children and adolescents. This study aimed to explore the relationship between autism spectrum disorder and internalizing and externalizing symptoms and whether grit and resilience moderates these relationships. Based …

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The Moderating Effects Of Self-Compassion On The Relationship Between Shame And Depression In Military Populations, Sarah Foran Jan 2025

The Moderating Effects Of Self-Compassion On The Relationship Between Shame And Depression In Military Populations, Sarah Foran

College of Graduate Studies: Theses & Dissertations

The U.S. Military has faced a continuous rise in mental health concerns reported by service members and veterans (Currier et al., 2017; Rosenheck & Fontana, 2007). Studies of military personnel have found that up to 15% of service members meet the criteria for experiencing depression (Shen et al., 2012). Often, individuals with military experience face numerous stressors that positively contribute to this experience of depression and feelings of shame (Bradbard et al., 2014; Litz et al., 2009). Military culture (often emphasizing shame related to mental health) has also been found to put military personnel at higher risk of experiencing depression …

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The Elite And The Illicit: Women, Power, And History In Cormac Mccarthy’S All The Pretty Horses And Cities Of The Plain, April Trepagnier Jan 2025

The Elite And The Illicit: Women, Power, And History In Cormac Mccarthy’S All The Pretty Horses And Cities Of The Plain, April Trepagnier

College of Graduate Studies: Theses & Dissertations

Much of the discussion concerning female characters in Cormac McCarthy’s oeuvre revolves around assertions of narrative misogyny and subjection resulting from overly reductive criticism based on identity singularity. Had the critics taken this approach with McCarthy’s male characters, there would be little discussion of his work today as they, too, would have appeared as shallow stereotypes. Such readings are of limited interest or usefulness. Rather, when readers pay attention to the richness of the literary craft of McCarthy’s works, it is possible to read his male characters with great complexity. The same treatment, applied to his female characters, reveals precisely …

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Educator Perceptions Of Crisis Frequency And Levels Of Preparedness In Rural Schools, Misty C. Duncan Jan 2025

Educator Perceptions Of Crisis Frequency And Levels Of Preparedness In Rural Schools, Misty C. Duncan

College of Graduate Studies: Theses & Dissertations

Recent national trends, particularly in rural education, highlight the urgent need for enhanced crisis prevention and intervention strategies. This study aimed to investigate the perceptions of crisis frequency and preparedness among rural educators. Through a survey, data were collected on participants' perceptions of crisis frequency and preparedness across various crisis areas. Preliminary findings revealed a significant gap between the perceived level of preparedness and the actual needs for school safety. Despite some training, the quantity and quality of training received by rural educators varied widely, impacting their preparedness to respond to crises. Moreover, an alarming percentage of educators reported not …

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Exploring Associations Between Health And Fitness Measures And Metabolic Syndrome Risk Factors In Rural Firefighters, Isaiah Mews Jan 2025

Exploring Associations Between Health And Fitness Measures And Metabolic Syndrome Risk Factors In Rural Firefighters, Isaiah Mews

College of Graduate Studies: Theses & Dissertations

This study investigates the relationship between metabolic syndrome (MetS) and muscular fitness measures in career rural firefighters. MetS is a cluster of conditions that increases the risk of cardiovascular disease (CVD), a leading cause of death among firefighters. Previous research has shown that cardiorespiratory fitness is inversely related to MetS, but the role of muscular fitness variables remains unclear. This study aims to determine if fitness measures, such as cardiorespiratory endurance, muscular strength, muscular endurance, and muscular power, can give insight into MetS in firefighters. Participants were recruited from a Southeastern rural fire department and underwent assessments of muscular fitness, …

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Does Friend Groups’ Co-Rumination Explain Depression Homophily Among Undergraduate Women's Friendship Groups?, Alyssa D. C. Klas Jan 2025

Does Friend Groups’ Co-Rumination Explain Depression Homophily Among Undergraduate Women's Friendship Groups?, Alyssa D. C. Klas

College of Graduate Studies: Theses & Dissertations

The transition to college is a period known for changes in social support and increases in depression risk. Undergraduate women are particularly vulnerable to developing internalizing symptoms like depression in response to relational stressors and social norm pressures associated with college life. Co-rumination, defined as excessive and ongoing discussion about problems and emotionally distressing topics, both fosters connection and intimacy between friends and increases risk of depressive symptoms. Thus, relationships that are typically seen as buffers from depression may, paradoxically, contribute to risk when support-seeking becomes maladaptive. Most research on co-rumination’s effects is limited to friendship dyads. However, within larger …

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“Stay Afloat, Stay Alive”: Stories Of The Challenges And Perseverance Of Foster Care Alumni In Higher Education, Marshall S. Parrent Jan 2025

“Stay Afloat, Stay Alive”: Stories Of The Challenges And Perseverance Of Foster Care Alumni In Higher Education, Marshall S. Parrent

College of Graduate Studies: Theses & Dissertations

The purpose of this critical narrative inquiry was to collect the stories of foster care alumni (FCA) in higher education, and so that we may better understand how FCA describe their experiences and what colleges and universities can do to help FCA achieve their goal of degree completion. This study highlights the need for a culturally responsive and sustaining curriculum in order to create an environment supportive of FCA needs. Undergraduate FCA are considered one of the most underserved student populations in higher education (Johnson, 2021). While 70-84% of FCA wish to attend college and earn a two- or four-year …

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Student Centers: The Intersection Of Campus Ecology And Sense Of Community, Caitlyn A. Wine Jan 2025

Student Centers: The Intersection Of Campus Ecology And Sense Of Community, Caitlyn A. Wine

College of Graduate Studies: Theses & Dissertations

Student centers are more than physical structures as they function as dynamic environments that serve as the hearthstone of campus, providing spaces for students to gather, connect, and engage. However, their role in fostering students’ sense of community remains underexplored. Grounded in campus ecology theory, this study explored whether time spent in the student center and specific forms of interaction predicted students’ sense of community. A quantitative survey design was employed, the Student Center and Sense of Community Intersection Survey (SCSCIS), to assess student center usage and perceived sense of community. Results indicated that time spent in the student center …

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Exploring The Impact: Eating Disorder Treatment And Mortality In The United States, Brittany Tolbert Jan 2025

Exploring The Impact: Eating Disorder Treatment And Mortality In The United States, Brittany Tolbert

College of Graduate Studies: Theses & Dissertations

This study explores adolescent eating disorder trends in the United States between 1999-2013, identifies national eating disorder mortality trends, and analyzes data for in-patient adolescent hospital admissions. Additionally, this study uses public-facing data for residential eating disorder treatment centers to explore issues related to insurance coverage, gender inclusivity, and evidence-informed treatment practices. The findings will highlight gaps in data collection and policy, support advocacy, and contribute to the research into eating disorder prevalence, prevention, treatment outcomes, and economic impact, leading to greater visibility to promote change.

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Correlates Of Body Image And Physical Self-Concept, Rashuna Middleton Jan 2025

Correlates Of Body Image And Physical Self-Concept, Rashuna Middleton

College of Graduate Studies: Theses & Dissertations

The growing overlap between social media and celebrity culture has played a significant role in shaping individuals' perceptions of body image and self-worth. This study explored the relationship between celebrity worship, problematic social media use, narcissism, physical self-concept, and body image among undergraduate psychology students. This study utilized the Celebrity Attitude Scale (CAS), the Narcissistic Personality Inventory (NPI), the Maladaptive Covert Narcissism Scale (MCNS), the Bergen Social Media Addiction Scale (BSMAS), the Body Influence Assessment Inventory (BIAI), the Self-Objectification Questionnaire (SOQ), and the Rosenberg Self-Esteem Scale (RSE). Findings indicated that vulnerable narcissism positively correlated with body image, whereas grandiose narcissism …

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Application Of Machine Learning And Large Language Models In Healthcare For Data Prediction And Summarization, Chiazam Chisom Izuchukwu Jan 2025

Application Of Machine Learning And Large Language Models In Healthcare For Data Prediction And Summarization, Chiazam Chisom Izuchukwu

College of Graduate Studies: Theses & Dissertations

This study aims to examine the use of machine learning (ML) and large language models (LLMs) in healthcare to enhance disease prediction, clinical decision-making, and information management. Five supervised ML models—Logistic Regression (LR), Support Vector Machine (SVM), Random Forest (RF), Decision Trees (DT), and Naïve Bayes (NB)—on three different computing platforms—Google Colab, Databricks, and Snowflake—were employed for disease classification. Data preprocessing included treating missing values, encoding categorical variables utilizing one-hot-encoding, feature scaling when needed, and tackling class imbalance with Synthetic Minority Over-sampling Technique (SMOTE) before an 80-20 train-test separation. Models were created with Scikit-learn (Google Collab), Spark MLlib (Databricks), and …

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Contextual Augmentation In Artificial Intelligence, Emmanuel Joshua Balogun Jan 2025

Contextual Augmentation In Artificial Intelligence, Emmanuel Joshua Balogun

College of Graduate Studies: Theses & Dissertations

Contextual understanding is a significant challenge of Large Language Models (LLMs), which are typically trained on general-purpose datasets. Due to this, LLMs fail to capture nuanced or domain-specific information and may struggle to interpret user queries accurately. Consequently, prompt engineering can become complex in automating, and LLMs are prone to “hallucinating”—generating random or irrelevant texts—when they lack sufficient context. This undermines their ability to provide focused, accurate responses. Accordingly, this thesis seeks to enhance the contextual understanding capabilities of Artificial Intelligence systems to facilitate more precise and relevant answer generation. Study A looks into a new approach to combating misinformation …

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Literary Homeplace As A Site Of Knowing And Healing, Shamonique Hassell Jan 2025

Literary Homeplace As A Site Of Knowing And Healing, Shamonique Hassell

College of Graduate Studies: Theses & Dissertations

The concept of literary homeplace serves as a locus of rhetorical healing for Black women, emphasizing their lived experiences and creative expressions as forms of resistance and restoration (Collins, 1986; hooks, 1990; Nettles, 2001). The labor of Black women within families, churches, and artistic endeavors contributes to the cultivation of a collective consciousness surrounding oppression and healing (Edwards, 2010; Carey, 2016; Morrison, 1992). Building upon hooks’ (1990) notion of homeplace, this dissertation examines how Black women foster spaces characterized by care, dignity, and resilience (Hersey, 2022; Tate, 1984). Using personal narrative and articulating Black women’s voices, I position homeplace as …

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Enhancing Ai-Driven Automation For Object Detection And Computer Vision, Nafeeul Alam Walee Jan 2025

Enhancing Ai-Driven Automation For Object Detection And Computer Vision, Nafeeul Alam Walee

College of Graduate Studies: Theses & Dissertations

In recent years, AI-driven automation has revolutionized the field of object detection and computer vision, enabling sophisticated and efficient solutions across various industries. This research explores the latest advances and techniques in improving AI-driven automation for object detection and computer vision applications. We examine state-of-the-art deep learning models and frameworks that have contributed to significant improvements in accuracy and speed and highlight the generative results. The focus is on exploring the real-time processing capabilities that have expanded the applicability of these technologies in real-world scenarios. Furthermore, we investigate image integration and video data to improve precision detection and contextual understanding. …

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Providing Healthcare Access For The African Population Using An International Care Coordination System: A Case Study Of Nigeria And Ghana, Aminat B. Nwaonumah Jan 2025

Providing Healthcare Access For The African Population Using An International Care Coordination System: A Case Study Of Nigeria And Ghana, Aminat B. Nwaonumah

College of Graduate Studies: Theses & Dissertations

Introduction: Healthcare access is a major population health challenge among underserved populations in many parts of the world, and the situation in Africa is no exception. Foreign aid, a significant component of healthcare financing in Africa, has played a crucial role in mitigating communicable diseases. However, there is a lacuna in care for non-communicable diseases, such as chronic illnesses, especially among the elderly. This study explored an innovative approach to expanding healthcare access in Nigeria and Ghana through care coordination sponsored by migrant family members residing in the United States. Beyond foreign aid, this research elucidates how the International Care …

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A Critical Examination Of Scent Avoidance And Olfactory Development After Neonatal Predator Scent Exposure, Cynthia Ware Jan 2025

A Critical Examination Of Scent Avoidance And Olfactory Development After Neonatal Predator Scent Exposure, Cynthia Ware

College of Graduate Studies: Theses & Dissertations

The long-standing assumption that predator odor avoidance in rodents is an innate survival mechanism has shaped decades of behavioral neuroscience research and underpins translational models of post-traumatic stress disorder (PTSD). However, developmental systems theory (DST) posits that behaviors emerge from dynamic interactions across physiological and environmental systems over time, rather than from fixed genetic programs. This study critically evaluates the developmental plasticity of predator scent aversion by examining whether early-life exposure to red fox urine (a natural predator odor) can attenuate avoidance behaviors in Long–Evans rats. Seventy-one rats were bred into three conditions: Control (no exposure), Partial (exposure from birth), …

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Barriers To Seeking Medical Care And Their Effects Among Fat Patients With A Fat Liberation Praxis In The United States, Christina Seiko Cook Jan 2025

Barriers To Seeking Medical Care And Their Effects Among Fat Patients With A Fat Liberation Praxis In The United States, Christina Seiko Cook

College of Graduate Studies: Theses & Dissertations

Weight stigma and weight bias have significant effects on the health of individuals (Alberga et al., 2019; Pearl, 2018; Puhl & Heuer, 2010; Schwartz et al., 2003; Udo et al., 2016). These biases can show up in the form of fatphobia or anti-fat bias. Physicians who hold anti-fat bias can affect their relationship with their patients, leading to poorer health outcomes and worse patient experiences for larger-bodied and fat people (Phelan et al., 2015). The purpose of this study is to contribute to the current literature regarding the positive and negative experiences of fat patients with a fat liberation praxis …

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Perceptions Of Agricultural Careers In African American School-Age Students Implications For Public Health Workforce, Brittany M. Prince Jan 2025

Perceptions Of Agricultural Careers In African American School-Age Students Implications For Public Health Workforce, Brittany M. Prince

College of Graduate Studies: Theses & Dissertations

This study evaluated a six-week enriched agricultural education curriculum on African American students’ knowledge and perceptions of agriculture and agricultural careers in two selected populations. The study aimed to expand awareness about agriculture and diverse agricultural career opportunities in an effort to reduce perceived stereotypes. The study employed a pre-post-test design, implemented at one middle school and one high school that were intentionally selected based on their population demographics. Participants included 108 students across both schools, with the majority identifying as African American. Data analysis included paired-sample t-tests and One-Way ANOVAs and revealed statistically significant increases in knowledge for middle …

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Synthesis And Characterization Of A Biobased Polymer From Tung Oil And Pine Rosin & Characterization Of Polyhydroxybutyrate., Arijanet P. Osumah Jan 2025

Synthesis And Characterization Of A Biobased Polymer From Tung Oil And Pine Rosin & Characterization Of Polyhydroxybutyrate., Arijanet P. Osumah

College of Graduate Studies: Theses & Dissertations

This thesis presents two independents but thematically aligned research projects focused on the development and evaluation of sustainable polymers. The first involves the synthesis and characterization of a biobased polymer derived from tung oil and pine rosin. Tung oil, which is a triglyceride was chemically modified to produce tung oil diglyceride (TDG), which subsequently reacted with abietic acid-rich pine rosin to yield tung oil abietate (TOA), a biobased monomer. The TOA monomer was polymerized with butyl methacrylate (BMA) and divinylbenzene (DVB) using di-tert-butyl peroxide (DTBP) as a thermal initiator. The resulting polymer was thoroughly characterized using Fourier transform infrared spectroscopy …

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Enhancing Adhd Diagnosis In College Students Using Multimodal Integration Of Nicats And Iva-2 Tools, Rushmila Shabneen Jan 2025

Enhancing Adhd Diagnosis In College Students Using Multimodal Integration Of Nicats And Iva-2 Tools, Rushmila Shabneen

College of Graduate Studies: Theses & Dissertations

This study explores enhanced methods for accurately identifying Attention Deficit Hyperactivity Disorder (ADHD) indicators in college students. ADHD, a neurodevelopmental disorder, impacts attention, impulse control, and emotional regulation, often leading to academic and social difficulties. Many students remain undiagnosed due to symptom overlap with stress and other factors. Traditional tools like the IVA-2 assess behavioral responses but may not fully capture ADHD complexity. This research integrates IVA-2 data with multimodal metrics from the Non-Intrusive Classroom Attention Tracking System (NiCATS), which monitors facial expressions, eye movements, and computer interactions. Preliminary results show that combining these tools improves ADHD detection, reduces false …

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Effects Of Perinatal Exposure To Lipopolysaccharide And Acetaminophen On Learning In Adult Long-Evans Rats, Lucy A. Sivils Jan 2025

Effects Of Perinatal Exposure To Lipopolysaccharide And Acetaminophen On Learning In Adult Long-Evans Rats, Lucy A. Sivils

College of Graduate Studies: Theses & Dissertations

The present study investigated the individual and combined effects of elevated perinatal inflammation, oxidative stress caused by acetaminophen (APAP) exposure, or elevated inflammation and oxidative stress on adult learning behaviors in Long-Evans rats. While prior studies have examined these factors independently, the combined effects of inflammation and oxidative stress via APAP exposure during early development on learning-related behaviors remain unexplored. The present research aimed to address this gap by the analysis of potential long-term neurodevelopmental consequences of lipopolysaccharide (LPS)-induced inflammation and APAP-induced oxidative stress. LPS, APAP, or LPS + APAP was administered during the perinatal period: postnatal days (PD) 9, …

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