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Mesenchymal Hippo Signaling In Lung Development And Disease, Kylie Klinkhammer Jan 2025

Mesenchymal Hippo Signaling In Lung Development And Disease, Kylie Klinkhammer

All ETDs from UAB

During both lung development and regeneration, the proper coordination of different cellular populations working in concert are vital to proper development and wound repairs. Myofibroblasts, highly contractile mesenchymal cells, are vital the organization of cells during lung development and to the remodeling of the extra cellular matrix (ECM) during regeneration. As important as myofibroblasts are, their apoptosis or differentiation to a less contractile phenotype is equally important to normal development and regenerative processes. Excessive differentiation of myofibroblasts or the improper localization of myofibroblasts are associated with pulmonary fibrosis, which is characteristic of lung disease, such as bronchopulmonary dysplasia or idiopathic …


Everyday Decision-Making Involvement Among Hispanic & Latinx Dementia Caregivers And Its Associations With Daily Anxiety And Daily Depressive Symptoms, Abigail Poe Jan 2025

Everyday Decision-Making Involvement Among Hispanic & Latinx Dementia Caregivers And Its Associations With Daily Anxiety And Daily Depressive Symptoms, Abigail Poe

All ETDs from UAB

Background: Hispanic and Latinx (H&L) caregivers of individuals living with Alzheimer’s disease and related dementias (ADRD) experience elevated caregiving burden and poorer mental health outcomes compared to caregivers from other racial and ethnic groups. Limited research has examined H&L caregivers’ involvement in everyday decision-making for persons living with dementia (PLWD), particularly how this involvement may relate to daily mental health symptoms such as anxiety and depression. Purpose: This study examined baseline decision-making involvement (DMI), its associations with individual-level factors, and its relationship with daily anxiety and depressive symptoms in H&L ADRD caregivers. Methods: A secondary analysis was conducted using data …


Regulatory Factors Associated With Discriminatory Behaviors Among Federally Qualified Health Centers, Miranda Leah Sedillo Jan 2025

Regulatory Factors Associated With Discriminatory Behaviors Among Federally Qualified Health Centers, Miranda Leah Sedillo

All ETDs from UAB

REGULATORY FACTORS ASSOCIATED WITH DISCRIMINATORY BEHAVIORS AMONG FEDERALLY QUALIFIED HEALTH CENTERS MIRANDA SEDILLO Executive Doctor of Science (DSc) in Healthcare Leadership Abstract Background Socially constructed classism restricts access to human rights, including employment and growth opportunities. The civil rights and labor movements have intersected throughout United States’ history as many civil rights leaders championed equal rights in employment opportunities. For several decades, the U.S. government has used laws and regulations to promote a healthy workplace free of discrimination. The influence of legal regulation on behavior change enforces punitive actions for discriminatory behaviors in the workplace. Yet, in 2020, the U.S. …


Prevalence Of Meibomian Gland Dysfunction In A Young Adult Population, Tyler Thomas Jan 2025

Prevalence Of Meibomian Gland Dysfunction In A Young Adult Population, Tyler Thomas

All ETDs from UAB

Background Meibomian gland dysfunction (MGD) varies in prevalence depending on the demographic and can significantly impact quality of life. There is a lack of research on MGD in young adult, professional student populations. Professional students often experience high levels of stress, reduced sleep, and increased electronic device use, which may elevate their risk for developing MGD. Specific Aims This cross-sectional clinical analysis has two specific aims: (1) to determine the prevalence of MGD in a young adult, professional student population, and (2) to identify potential risk factors and clinical assessments correlated with MGD. Methods A total of 147 professional students …


Uncovering The Role Of Heparanase-Armed Extracellular Vesicles In Sepsis-Associated Vascular Endotheliopathy, Robert Patrick Richter Jan 2025

Uncovering The Role Of Heparanase-Armed Extracellular Vesicles In Sepsis-Associated Vascular Endotheliopathy, Robert Patrick Richter

All ETDs from UAB

Sepsis remains one of the most frequent causes of mortality and life-altering morbidity in humans of all ages globally. Though sepsis pathobiology is incompletely understood, it is clear that a unifying feature of all sepsis phenotypes is systemic vascular endotheliopathy and damage to the luminal glycocalyx of endothelial cells, or eGC, that leads to organ injury. While prior work has established that heparan sulfate (HS) is an especially important eGC constituent that helps regulate a host of endothelial cell (EC) functions, its role in promoting endotheliopathy during sepsis has not been fully characterized. Additionally, previous studies in the context of …


An In-Depth Review Of Food Insecurity In College Students Enrolled In Alabama Historically Black Colleges And Universities, Janice Dansby Washington Jan 2025

An In-Depth Review Of Food Insecurity In College Students Enrolled In Alabama Historically Black Colleges And Universities, Janice Dansby Washington

All ETDs from UAB

Food insecurity is a common issue in the United States (US), and special attention has been given to college students. There is empirical evidence of high food insecurity among African American students at Historically Black Colleges and Universities (HBCUs) (Duke et al., 2023; Dahl et al., 2022; Goldrick-Rab et al., 2018). The current research explores the food-insecure conditions of college students at HBCUs in Alabama, appealing for more studies highlighting the role of all stakeholders in combating this issue. The research questions posed in this study are significant, as they are expected to yield vital information regarding the experiences and …


Chronic Pain And Resilience: Associations And Interactions With Diet, Asia Wiggins Jan 2025

Chronic Pain And Resilience: Associations And Interactions With Diet, Asia Wiggins

All ETDs from UAB

Chronic pain is a significant issue globally, affecting millions of people. One relatively new way mechanism to reduce pain is to promote resilience. Yet, the effect of resilience on chronic pain may differ by sociodemographic factors (like racialized group). Furthermore, access to therapies that promote resilience may be limited across populations. However, the utilization of diet interventions for chronic pain symptoms has also been well-examined. In addition, research has shown that diets can be related to psychological resilience. Therefore, beneficial diets could potentially be utilized as a catalyst to, not only promote resilience, but also reduce pain (in combination with …


Nursing Professional Liability: Bridging Rn & Aprn Perspectives On Risk, Coverage & Evolving Practice Authority, Michelle Hileman Msm, Rn, Cnm, Parkview Health Jan 2025

Nursing Professional Liability: Bridging Rn & Aprn Perspectives On Risk, Coverage & Evolving Practice Authority, Michelle Hileman Msm, Rn, Cnm, Parkview Health

Nursing Publications, Posters, & Presentations

Presented at the 2025 Parkview Nursing Research Symposium.

The purpose of this literature review is to explore professional liability for RNs and APRNs. Specific objectives include:

• Identify patterns in malpractice claims for RNs and APRNs

• Compare employer-provided and personal malpractice coverage

• Examine the impact of scope-of-practice laws on APRN liability

• Clarify principles of vicarious liability

• Recommend lifelong strategies for education, risk management, and professional practice


Provider Perspectives On Produce Prescription Programs In A Rural Community, Heather Ward Dnp,Fnp-Bc, Sarah Giaquinta Md, Mph, Susan Storey Phd, Rn, Aocns Jan 2025

Provider Perspectives On Produce Prescription Programs In A Rural Community, Heather Ward Dnp,Fnp-Bc, Sarah Giaquinta Md, Mph, Susan Storey Phd, Rn, Aocns

Nursing Publications, Posters, & Presentations

This poster was presented at the 2025 Nursing Research Symposium.

Purpose:

  • To evaluate healthcare provider perspectives on PPPs in a rural community
  • To identify barriers and facilitators to implementing a PPP
  • To lay the groundwork for the successful implementation of a PPP in the Count


Pairing Vashe And Cavilon Advanced Skin Protectant For An Innovative Approach To Neonatal Diaper Dermatitis Treatment, Jennifer Thieman Msn, Rn, Accns-P, Rnc-Nic, C-Elbw, Cls Jan 2025

Pairing Vashe And Cavilon Advanced Skin Protectant For An Innovative Approach To Neonatal Diaper Dermatitis Treatment, Jennifer Thieman Msn, Rn, Accns-P, Rnc-Nic, C-Elbw, Cls

Nursing Publications, Posters, & Presentations

This poster was presented at the 2025 Nursing Research Symposium.

Objective: To implement a new process that allows Vashe and Cavilon Advanced Skin Protectant to be used together in order to improve healing time of diaper dermatitis.


Tiered Skills Acquisition Model Implementation Parkview Health Centers For Wound Healing, Harlee Heller Bsn, Rn,Csmrn, Ariel Custer Bsn, Rn Jan 2025

Tiered Skills Acquisition Model Implementation Parkview Health Centers For Wound Healing, Harlee Heller Bsn, Rn,Csmrn, Ariel Custer Bsn, Rn

Nursing Publications, Posters, & Presentations

This poster was presented at the 2025 Parkview Nursing Research Symposium.

Implement TSAM at Parkview Centers for Wound Healing to:

  • Ensure consistent delivery of high-quality nursing care
  • Establish standardization to equip nurses to float between outpatient wound clinic locations, promoting flexibility and operational efficiency
  • Support preceptor flexibility to continue an orientee’s training, regardless of the availability of the primary preceptor, expediting orientation
  • Increase confidence of outpatient wound care nurses for independent practice following orientation
  • Increase nursing retention rates


Three Wishes Project: Individualizing End Of Life Care, Sarah Seddon Rn Jan 2025

Three Wishes Project: Individualizing End Of Life Care, Sarah Seddon Rn

Nursing Publications, Posters, & Presentations

This poster was presented at the 2025 Nursing Research Symposium. •We used the journal article to create tangible ways to individualize the dying process •A binder ways created with the different “wishes” nurses can provide.


Optimizing Defibrillation Response: A Quality Improvement Initiative In The Cath Lab, Sara Cullis Bsn, Rn Jan 2025

Optimizing Defibrillation Response: A Quality Improvement Initiative In The Cath Lab, Sara Cullis Bsn, Rn

Nursing Publications, Posters, & Presentations

This poster was presented at the 2025 Parkview Nursing Research Symposium.

Patients undergoing diagnostic or emergent procedures in the Cardiac Cath Lab are at risk of developing lethal arrhythmias, which require immediate defibrillation to prevent adverse outcomes. Currently, the use of paddles and the absence of pre-applied defibrillator pads delay response time during critical events, increasing the risk of morbidity and mortality. Additionally, there is a liability when staff assume which patients are “high risk” versus “diagnostic,” as even seemingly low-risk cases can rapidly deteriorate without warning. This quality improvement initiative aims to address this gap by ensuring defibrillator pads …


Best Practice In Geriatric Fracture Care: Impact Of Early Urinary Catheter Removal On Cauti Incidence, Samantha Tiede Bsn, Rn, Onc, Heather Kegerreis Msn, Rn, Cmsrn Jan 2025

Best Practice In Geriatric Fracture Care: Impact Of Early Urinary Catheter Removal On Cauti Incidence, Samantha Tiede Bsn, Rn, Onc, Heather Kegerreis Msn, Rn, Cmsrn

Nursing Publications, Posters, & Presentations

Poster presented at the 2025 Parkview Nursing Research Symposium.

Objective: Evaluate the effectiveness of urinary catheter removal by POD1 on CAUTI incidence in GFPs.


Use Of Machine Learning Models To Predict Microaspiration Measured By Tracheal Pepsin A., Annette Bourgault, Ilana Logvinov, Chang Liu, Rui Xie, Jan Powers Phd, Rn, Ccrn, Mary Lou Sole Jan 2025

Use Of Machine Learning Models To Predict Microaspiration Measured By Tracheal Pepsin A., Annette Bourgault, Ilana Logvinov, Chang Liu, Rui Xie, Jan Powers Phd, Rn, Ccrn, Mary Lou Sole

Nursing Publications, Posters, & Presentations

BACKGROUND: Enteral feeding intolerance, a common type of gastrointestinal dysfunction leading to underfeeding, is associated with increased mortality. Tracheal pepsin A, an indicator of microaspiration, was found in 39% of patients within 24 hours of enteral feeding. Tracheal pepsin A is a potential biomarker of enteral feeding intolerance.

OBJECTIVE: To identify predictors of microaspiration (tracheal or oral pepsin A). It was hypothesized that variables predicting the presence of tracheal pepsin A might be similar to predictors of enteral feeding intolerance.

METHODS: In this secondary analysis, machine learning models were fit for 283 adults receiving mechanical ventilation who had tracheal and …


Cultivating Plain Language Skills For Engineering Students, Catherine Wong, Cynthia Carlson Jan 2025

Cultivating Plain Language Skills For Engineering Students, Catherine Wong, Cynthia Carlson

Faculty Publications

While engineers are learning the vocabulary of the profession, understandably, they want to practice, and perhaps show their professors that they are proficient. This leads to student writing that is overly complicated and full of jargon. This is not the type of document that would be clear to the public, or even to a professional outside of the narrowly focused field of the particular engineer. After graduation, engineers’ writing becomes exponentially more important. Often approval of projects relies on residents’ or clients’ understanding of engineers’ work. For example, an engineering firm completing an investigation of an important health concern such …


Data Literacy Competencies In Context: Employee Perspectives From The Workplace, Patricia Condon, Wendy G. Pothier Jan 2025

Data Literacy Competencies In Context: Employee Perspectives From The Workplace, Patricia Condon, Wendy G. Pothier

Faculty Publications

Data literacy is essential in today’s workplace, and professionals across roles and experience levels recognize its value. This article reports on findings from interviews with 16 supply chain and logistics professionals. The study examines how seven proposed data literacy competencies align with workplace needs, how employees address the data literacy gap, and how librarians can support workforce readiness. Findings highlight opportunities for libraries to bridge the data literacy gap through instruction and resources development that integrate technical and non-technical data skills with information literacy.


Overturning Roe V. Wade And Pre-Medical Students’ Views And Medical School Choices, Emma J. Hastings, M. Courtney Hughes Jan 2025

Overturning Roe V. Wade And Pre-Medical Students’ Views And Medical School Choices, Emma J. Hastings, M. Courtney Hughes

Faculty Articles, Papers, and Other Scholarship

The overturning of Roe v. Wade in Dobbs v. Jackson Women’s Health Organization (2022) has led to varying abortion laws across states in the U.S., potentially influencing medical education choices. While some research has examined abortion policy changes and medical residencies and fellowship decisions, none has investigated abortion policy and medical school decisions. This study aims to determine whether pre-medical students’ personal views on abortion influence their willingness to attend medical schools in states where abortion is illegal at all stages EXCEPT to save the life of the mother. A cross-sectional survey was distributed to pre-medical organizations at the two …


Utilizing 16s Rna Sequencing To Identify Bacterial Species Colonizing Lame Birds With Bacterial Chondronecrosis With Osteomyelitis, Kara Hoover, Andi Asnayanti, Adnan Alrubaye Jan 2025

Utilizing 16s Rna Sequencing To Identify Bacterial Species Colonizing Lame Birds With Bacterial Chondronecrosis With Osteomyelitis, Kara Hoover, Andi Asnayanti, Adnan Alrubaye

2025 Research Poster Competition

Poultry lameness has become prevalent in recent years due to high growth rates in broiler chickens. Bacterial chondronecrosis with osteomyelitis (BCO), the main cause of lameness, is characterized by necrosis of the femur and tibia in afflicted birds. Heavier birds are more susceptible to bacterial stress in these regions due to increased pressure on their growth plates. BCO lameness poses both ethical and financial threats to the poultry industry, as up to 15% of flocks can become affected during outbreaks. The purpose of this experiment was to identify bacterial species present in birds with BCO lameness. 1,800 chicks were randomly …


Breaking Barriers: Designing An Effective Early Intervention Process For Enhanced Developmental Outcomes In Private Schools, Breanne Kristen Cox Jan 2025

Breaking Barriers: Designing An Effective Early Intervention Process For Enhanced Developmental Outcomes In Private Schools, Breanne Kristen Cox

Graduate Student Dissertations, Theses, Capstones, and Portfolios

The challenge of ensuring inclusive and equitable support for students with disabilities is increasingly prominent in education, particularly in private school settings. This dissertation explored the implementation and effectiveness of an early literacy intervention process, the “Bright Beginnings Boost Initiative,” in a small Montessori preschool in South Florida. The study addresses the gap in support services for students with disabilities in private schools, which often lack the comprehensive frameworks mandated by public education systems under the Individuals with Disabilities Education Act (IDEA).

Through a qualitative two-phase action research design, this study gathered insights from preschool teachers, the preschool director, the …


An Operational Field Study: A Comparison Of Piloting Uncrewed Underwater Vehicles And Uncrewed Aircraft Systems, David Thirtyacre, Joseph Cerreta, Pete Miller, Kimberly Luthi, Jolee Thirtyacre Jan 2025

An Operational Field Study: A Comparison Of Piloting Uncrewed Underwater Vehicles And Uncrewed Aircraft Systems, David Thirtyacre, Joseph Cerreta, Pete Miller, Kimberly Luthi, Jolee Thirtyacre

Publications

and operations, the ability to cross-train personnel in both Uncrewed Underwater Vehicles and Small Uncrewed Aircraft System operations has become a focal point for efficiency and workforce optimization. This study presents a comparative analysis of the operational and human factor considerations involved in piloting mini UUV and sUASs, highlighting the key similarities and differences in control methods, environmental influences, navigation, emergency procedures, and situational awareness. A qualitative experimental field study was conducted between July 2024 and October 2024, involving real-world deployments of both systems in maritime and aerial environments. Findings indicated that while UUV and sUAS operators relied on remote …


Factors Contributing To Fatalities In Helicopter Emergency Medical Service Accidents, Jenna Korentsides, Joseph R. Keebler, Mihhail Berezovski, Alex Chaparro Jan 2025

Factors Contributing To Fatalities In Helicopter Emergency Medical Service Accidents, Jenna Korentsides, Joseph R. Keebler, Mihhail Berezovski, Alex Chaparro

Publications

INTRODUCTION: T his study aimed to update and reinforce previous research on helicopter emergency medical service accidents in the United States. By investigating predictors of fatalities after helicopter emergency medical service crashes through the application of machine learning techniques, we updated existing data sets and sought to uncover patterns that traditional analysis might not reveal.

METHODS: Using the National Transportation Safety Board database, the authors analyzed a dataset of 267 helicopter emergency medical service accidents between 1991–2022. We first calculated fatalities odds ratios for each condition. We then plotted geospatial locations of all reported accidents. Finally, we used XGBoost regression …


High Neuraxial Blockade In A Parturient After Epidural Placement: A Quality Improvement Simulation., Samir Patel, Noah D Le, John Carter, Nick Melott, Andrew Kalnow, Camille D Hawkins, Alexander Luong, Matthias Franzen Jan 2025

High Neuraxial Blockade In A Parturient After Epidural Placement: A Quality Improvement Simulation., Samir Patel, Noah D Le, John Carter, Nick Melott, Andrew Kalnow, Camille D Hawkins, Alexander Luong, Matthias Franzen

Medical Education Articles

Background Epidural anesthesia is a commonly used procedure in obstetrics for managing labor pain, with a potential complication of high neuraxial blockade. Proficiency in performing epidural or spinal anesthesia and promptly recognizing and managing high neuraxial blockade are critical components of anesthesiology residency training. Methods A simulated case was designed involving a 21-year-old female in labor receiving epidural anesthesia. After the administration of local anesthetic, she develops symptoms of nausea, hypotension, and respiratory distress, progressing to high neuraxial blockade. The simulation environment included a labor and delivery suite setup, an epidural cart, airway supplies, a Laerdal SimMan 3G PLUS mannequin …


Adverse Childhood Experiences, Somatic Symptoms, And Athletic Injury Among Collegiate Student-Athletes, Samuel Aswegan Jan 2025

Adverse Childhood Experiences, Somatic Symptoms, And Athletic Injury Among Collegiate Student-Athletes, Samuel Aswegan

Research Papers

No abstract provided.


Probiotic Supplementation In Ruminants: A Sustainable Alternative For Enhancing Health, Milk Production, And Rumen Function, Jovahna Williams Jan 2025

Probiotic Supplementation In Ruminants: A Sustainable Alternative For Enhancing Health, Milk Production, And Rumen Function, Jovahna Williams

Research Papers

This paper examines the effects of probiotic supplementation on ruminant animals, with emphasis on several key areas including ruminant animal health, milk production, rumen microbial profile, microbial protein synthesis and diversity, and patterns of rumen fermentation. As global interest in economically and biologically sustainable alternatives to antibiotics continues to grow, probiotics have emerged as promising candidates for improving livestock productivity while promoting animal and consumer welfare.

The primary objectives of this paper are to evaluate the specific effects and benefits of different probiotic strains in ruminants, to assess their potential as replacements for traditional growth-promoting substances such as fermentation enhancers …


Comparisons Of Major Healthcare Systems In Europe And The United States Through The 20th And 21st Century, Isaac Shaw Jan 2025

Comparisons Of Major Healthcare Systems In Europe And The United States Through The 20th And 21st Century, Isaac Shaw

Research Papers

This paper examines how healthcare systems have been created in four countries, the USSR (and then Russia post 1991), Poland, Germany and the United States, how they changed throughout the decades, their efficacy, as well as focusing on aspects such as funding, budget allocation, care quality, and the overall structure of the system. These cases were chosen to give a contrast between the development and subsequent abandonment of the Soviet Semashko system which proposed an entirely state ran and centralized program that was imposed on other Soviet Bloc Countries and the United States’ decentralized employer led health insurance system. Germany …


Molecular Interactions Between The Shellfish Pathogen Vibrio Coralliilyticus Re22 And The Probiont Phaeobacter Inhibens S4sm, Jessica Coppersmith Jan 2025

Molecular Interactions Between The Shellfish Pathogen Vibrio Coralliilyticus Re22 And The Probiont Phaeobacter Inhibens S4sm, Jessica Coppersmith

Open Access Dissertations

Oyster larvae aquaculture is an important industry, both economically and environmentally, helping to create sustainable food systems by supplying seed oysters to farms, and also to restoration projects aimed at building coastal resilience and improving water quality by rejuvenating wild populations. However, oyster larvae are highly susceptible to rapid mortality events, crashes, which can seriously impact the industry. One source of these crashes in hatchery systems is vibriosis, caused by pathogenic species of Vibrio bacteria that are ubiquitous in temperate coastal waters, and with rising surface water temperatures their prevalence and virulence are increasing. To prevent these larval crashes from …


Searching Effectively: Basic Principles And Practical Tips For Better Results, Roy E. Brown Jan 2025

Searching Effectively: Basic Principles And Practical Tips For Better Results, Roy E. Brown

VCU Libraries Faculty and Staff Publications

This handout updates Doing a Good Search: Basic Rules and Search Tips, originally published in 2024. It outlines the basic principles of doing a good search, from identifying a topic and formulating a clear question to selecting and searching at least two databases. It also includes information on Boolean operators (AND, OR, NOT), subject headings, and Google Scholar. New to this iteration of the document are best practices for using artificial intelligence in literature and evidence searches.

Remember: Searching is an iterative process, which involves repeated cycles of refinement. Your approach will shift depending on the specific question you're trying …


To Manufacture And Sell: The Erosion Of Gun Manufacturers' Immunity Under Plcaa's Predicate Exception Extending Liability For Cartel Violence, Jessica Spurling Jan 2025

To Manufacture And Sell: The Erosion Of Gun Manufacturers' Immunity Under Plcaa's Predicate Exception Extending Liability For Cartel Violence, Jessica Spurling

Penn State Law Review (2003 - Present)

No abstract provided.


Closing The Gap: Resolving The Circuit Split On Prior Pay In Equal Pay Act Claims, Jessica Shoemaker Jan 2025

Closing The Gap: Resolving The Circuit Split On Prior Pay In Equal Pay Act Claims, Jessica Shoemaker

Penn State Law Review (2003 - Present)

No abstract provided.