Digital Commons Network^™

Deciphering Genetic Contributions To Antibiotic Persistence: Insights From Multi-Gene Knockout Studies, Elise K. Schweer

Electronic Theses and Dissertations

Antibiotic resistance is a critical global health challenge, complicating efforts to treat bacterial infections effectively. Antibiotic persistence plays a significant role in driving resistance. Persisters are a subpopulation of non-dividing bacterial cells that often evade lethal antibiotic treatment. Once antibiotics are removed, these cells "resurrect," resuming growth and may lead to relapsing infections. Notably, the progeny of persister cells exhibit a heightened tendency to acquire mutations or incorporate antibiotic resistance genes, further compounding the challenge of antibiotic resistance. In our recent study, we knocked out seven hypothetical genes and observed a significant reduction in persister levels. Compared to the wild …

Optimizing Heifer Development On Dormant Rangelands By Integrating Precision Livestock Technologies With The Range Supplementation Model And The Evaluation Of Short-Term Rotations Of Precision Technology On Plant Communities, Hadley Ann Dotts

Electronic Theses and Dissertations

Heifer development on dormant rangelands offers a cost-effective alternative to feedlot or drylot systems. However, traditional bunk supplementation methods often result in uneven intake, inefficient feed use, and ecological degradation around static feeding sites. This thesis evaluated the integration of precision livestock technologies and a dynamic Range Supplementation Model to improve individual animal performance, weight uniformity, and rangeland sustainability in extensive heifer development systems in the Northern Great Plains. The first study involved a seven-month trial (November 2023–May 2024) with 50 yearling Angus heifers grazing dormant native rangelands at the SDSU Cottonwood Field Station. Heifers were stratified into two treatments: …

Biotransformation Of Camelina Meal Via Pretreatment And Fermentation For Functional And Nutritional Upgrading, Ram Kumar Bhattarai

Electronic Theses and Dissertations

Camelina sativa, an oilseed crop of the Brassicaceae family, has seen increased cultivation in North America in response to the rising demand for biofuels over the past two decades. With this growth, camelina meal, a byproduct of oil extraction, has emerged as a promising yet underutilized resource, particularly for applications in animal nutrition. This study aimed to evaluate the potential of camelina meal as a substrate for submerged fungal fermentation and to examine how this bioconversion affects its physicochemical and nutritional properties. The influence of mild pretreatments (unwashed, washed only, and washed/dried and ground) on fermentation outcomes was also assessed. …

Frequency And Perceived Influence Of Menopausal Symptoms On Training And Performance In Female Endurance Athletes, Heather M. Hamilton, Natalie M. Yarish, Kristin E. Heron

Rehabilitation Sciences Faculty Publications

Menopause is associated with several negative health concerns and common menopausal symptoms. Physical activity is essential to mitigate these negative effects, but menopausal symptoms may interfere with participation in physical activity. The purpose of this study was to determine the frequency and the perceived negative effect of menopausal symptoms among female endurance athletes. Female runners, cyclists, swimmers, and triathletes 40–60 years of age were recruited (N = 187). Participants completed an online, anonymous survey that included self-reported menopausal status; the Menopausal Rating Scale (MRS), a validated measure for assessing menopausal symptoms; and the perceived effect of menopausal symptoms on …

Burnout In Board-Certified Behavior Analysts, Casey J. Kane

PCOM Psychology Dissertations

Burnout is a pervasive challenge among board-certified behavior analysts (BCBAs) due to the high performance demands and extensive workload associated with their roles. This study investigated the effectiveness of a self-advocacy intervention in mitigating burnout among BCBAs. Using a waitlist control design with repeated measures, nine BCBAs participated in an asynchronous intervention focused on communication, organization, and self-care strategies. Burnout levels were measured at baseline, post-waitlist, and post-intervention using the Oldenburg Burnout Inventory. Results showed a reduction in burnout levels, with improvements in disengagement and exhaustion scores across participants. Additionally, the intervention increased the frequency of behaviors associated with burnout …

Parasocial Relationships And Women’S Friendship Expectations, Perceptions, And Satisfaction, Renee N. Plaza

PCOM Psychology Dissertations

Television (TV) and film have increasingly become meaningful ways for people to connect, whether through discussing content, engaging with celebrities online, or forming imagined relationships with fictional characters. These one-sided connections are known as parasocial relationships (PSR). While prior research has mainly focused on how PSR influence romantic relationships—affecting ideals, expectations, perceptions, and satisfaction—the current study expands this examination to non-romantic relationships, specifically friendships.

The aim of this research is to explore how stronger non-romantic PSR might influence an individual's expectations, beliefs, perceptions, and overall satisfaction with their real-life friendships. Participants completed several assessments, including the Parasocial Relationship Measure, Relationship …

Predictors Of Mental Health Services Use In Integrated Primary Care During Covid-19, Joseph D. Harrison

PCOM Psychology Dissertations

The purpose of this study was to identify the predisposing, need, and enabling factors that predict mental health services use before and during COVID-19 in an integrated primary care network in the Philadelphia metropolitan area. This retrospective observational study examined a sample of primary care patients from January 2018 to February 2020 (i.e., pre-COVID-19) and March 2020 to December 2022 (i.e., peri- COVID-19) using electronic health record data. Mental health services use was defined as the number of appointments attended by patients. A hierarchical regression was conducted to identify predictors of mental health services use by sequentially adding sociodemographic predisposing …

Evaluating Online Resources: Providing Parents With Reliable Emotional Intelligence Training Tools, Melissa Van Embden

PCOM Psychology Dissertations

The rise of online resources has produced a shift in how parents seek guidance in fostering their child’s emotional intelligence (EI). Yet, the quality and accessibility of these resources remain largely unexamined. This study evaluates the top Google search results generated from six prompts designed to reflect the information-seeking behavior of parents looking to develop their child’s EI. Using an incognito browser, the first 20 links for each prompt were recorded, with Google Gemini AI-generated responses specifically marked. The researcher vetted the recorded links by utilizing a comprehensive checklist assessing professional credibility, communication and engagement features, and pricing. The Findings …

Exploring Screen Time Trends Among Children With Autism Spectrum Disorder: A Quantitative Survey Analysis, Jessica Rachel Ponzo

PCOM Psychology Dissertations

Research exploring the trends, motivations, and parental influences of screen use among children with autism spectrum disorder (ASD) is limited. The purpose of this study was to address these gaps by examining screen time habits among children with ASD. Specifically, it explored the duration of screen time, screen-based activities, device ownership, parental mediation strategies, functional uses of screens, and caregiver perceptions of children’s screen time. Besides entertainment, children with ASD also use screens for emotional regulation, sensory seeking, accessing restricted interests, and communication, including Augmentative and Alternative Communication (AAC) devices. The data for this study were collected using a quantitative …

Anxiety And Self-Esteem In Adolescents And Young Adults Undergoing Bariatric Surgery, Julia Nikolajuk

PCOM Psychology Dissertations

Bariatric surgery, a medical procedure that alters an individual’s digestive system, has gained popularity in the last several years as a weight loss method. After this surgery, many individuals report improvements with their quality of life as they lose weight, change unhealthy eating patterns, experience a decrease in symptoms of depression, and gain a strong sense of self-esteem. However, research has found increased rates of depressive symptoms and patterns of disordered eating associated with obesity and bariatric surgery, but little research exists regarding anxiety and bariatric surgery with adolescents and young adults. The purpose of this study was to clarify …

Acculturation, Self-Esteem, Family Norms, And Disordered Eating Behaviors In South Asian Women, Angela Abraham

PCOM Psychology Dissertations

This study investigated the relationships among acculturation, self-esteem, family norms, and disordered eating behaviors among South Asian women living in the United States. Although research suggests culture plays a role in the etiology of eating disorders, little information on the experiences of South Asian women exists. This study sought to fill this gap in the literature. Using a cross-sectional, quantitative survey-based design, 151 South Asian women provided insight into their experiences with family norms, acculturation, self-esteem, and eating behaviors. Results indicated that acculturation was not significantly associated with disordered eating. However, self-esteem was found to be negatively associated with disordered …

Identifying Needs Of School-Age Children With Cardiospondylocarpofacial Syndrome, Erin Henning

PCOM Psychology Dissertations

Advancements in genetic testing have led to the identification of many rare genetic conditions, yet comprehensive knowledge of their broader impacts remains limited. Most existing research focuses narrowly on medical outcomes. Cardiospondylocarpofacial Syndrome (CSCF) is an ultra-rare genetic condition for which little is known beyond its physical manifestations. This descriptive case series study examined the behavioral, social, emotional, and academic functioning of eight school-aged children diagnosed with CSCF, as well as the experiences of their families. Participants were recruited from North America, Europe, and Australia via a private Facebook group. Data were collected through an open-ended, written questionnaire completed by …

The Role Of Teacher Engagement In Enhancing Children’S Organizational Skills: A School-Based Intervention Study, Brooke Goldsmith

PCOM Psychology Dissertations

Executive functioning skills, including organization, time management, and planning (OTMP), are critical for an individual across the lifespan. Deficits in these skills can negatively impact academic achievement, social-emotional functioning, and future occupational opportunities and satisfaction. Organizational Skills Training (OST) interventions have been shown to improve OTMP skills in children, however, less is known about the role of teacher engagement in supporting these interventions. The current study examined the relationship between teacher engagement in a school-based Organizational Skills Training-Tier 2 program (OST-T2), and improvements in student organizational skills outcome. Secondary data were analyzed from 96 students in grades 3-6 and their …

Predictors Of Psychologists’ Self-Reported Knowledge And Self-Perceived Competence In Treating Transgender Clients, Tara N. Bennett

PCOM Psychology Dissertations

It has been widely recognized that transgender (trans) and gender nonconforming (TGNC) populations face significantly greater rates of depression, anxiety, substance use, and suicidality than the general population. Despite these risks, little research has analyzed how psychologists are prepared to provide culturally competent therapy to trans clients or what predicts competence in treating this population. This study aimed to identify what factors predict psychologists’ selfperceived knowledge and self-perceived competence in working with trans clients. The study’s secondary aim was to collect information about how psychologists receive education related to trans clients. This study employed a correlational research design to examine …

Promoting Perinatal Mental Well-Being: Empowering Healthcare Professionals, Deborah Flam

PCOM Psychology Dissertations

This pilot study aimed to address the critical need to enhance healthcare providers’ knowledge and shift their beliefs regarding perinatal mental health disorders through the development and implementation of a targeted educational workshop, “Promoting Perinatal Mental Health Well-Being”, designed to improve their understanding and attitudes toward identifying, treating, and supporting affected individuals. Using a qualitative approach, pre- and post-tests were administered to assess changes in knowledge and beliefs. While statistical significance was not achieved, likely due to a small sample size, prior training among participants, and other limitations, the findings revealed a meaningful shift in provider beliefs. Participants reported increased …

(In)Animate: Exploring The Relationship Between Obsessivecompulsive Disorder, Perceived Thought Control, And Anthropomorphism, Kaitlyn O’Neill

PCOM Psychology Dissertations

Introduction: Ritual behaviors help manage uncertainty and anxiety by providing a sense of control, but rigid engagement in such behaviors can indicate obsessivecompulsive disorder (OCD). Most OCD research has focused on harm-avoidance versus "not-just-right-experiences" (NJREs), with exposure and ritual prevention (ERP) being less effective for those without clear feared outcomes. Anthropomorphizing, or assigning human traits to objects, complicates OCD treatment, particularly for those with hoarding behaviors.

Objectives: This study aimed to examine the relationship between OCD with and without hoarding behaviors ("saving" behavior) and anthropomorphism. Given ERP’s role in OCD treatment, understanding how anthropomorphism affects OCD is crucial. It was …

Impact Of Pcos Knowledge And Treatment Recommendations On Women’S Quality Of Life, Sydni Yadin

PCOM Psychology Dissertations

Polycystic ovary syndrome (PCOS) is a chronic endocrine disorder affecting 15–20% of women of reproductive age (Krug et al., 2019). Characterized by hyperandrogenism, irregular menstrual cycles, and ovarian cysts, PCOS is associated with obesity, insulin resistance, and infertility (Correa et al., 2015). These complications can significantly diminish women’s quality of life. This study investigated the relationship between women’s knowledge of PCOS health outcomes, providers’ use of lifestyle management interventions, and quality of life. A cross-sectional survey design was used, and participants completed the PCOS Quality of Life Scale (Williams et al., 2018). It was hypothesized that greater knowledge of PCOS …

A Qualitative Study Of Euphemistic Language And Identity Development Involving Sexual Assault, Keena Stewart

PCOM Psychology Dissertations

According to the Centers for Disease Control and Prevention, sexual violence refers to a situation in which sexual activity occurs and consent is not obtained or freely given. Sexual violence is a worldwide epidemic that impacts individuals of all communities, genders, ages, and sexual orientations. When considering the impact of sexual violence, the use or misuse of language is fundamental. Furthermore, the recovery process following a sexual assault is directly related to the presence or absence of resiliency factors. The purpose of this study was to explore and understand the effects of euphemized language on the identity development of individuals …

Predictors Of Anxiety And Depression In Dental Students - A Nationwide Study, Margaret Xiaojiao Yang

PCOM Psychology Dissertations

Student mental health is a growing concern in higher education, particularly within rigorous clinical training programs. This study estimated the prevalence of anxiety and depression among U.S. dental students and examined associations with resilience and perceived institutional and faculty support. A cross-sectional survey was administered to more than 1,100 full-time students at over 30 accredited dental schools. The instrument collected demographics, the Brief Resilience Scale (BRS), the Generalized Anxiety Disorder–7 (GAD-7), the Patient Health Questionnaire–9 (PHQ-9), and four items assessing perceived support. Among respondents who completed the GAD-7 (n = 965), 43% scored ≥ 8, indicating probable generalized anxiety disorder. …

Pediatric Anxiety Disorders: Therapy Process Predictors Of Response To Cbt, Samantha Baker

PCOM Psychology Dissertations

CBT is moderately effective in the treatment of youth anxiety, yet there remains a sizeable number of youth who remain nonresponsive at posttreatment, and less than half achieve remission. Various patient-level variables have been examined concerning differential treatment outcomes for anxious youth, but fewer studies have examined therapy process variables. Using archival data, this study aimed to identify predictors of treatment response in youth with primary anxiety disorders who completed 16-weeks of CBT at a university-based clinic. Four samples of anxious youth, aged 7-17 were included in the analysis. Regression analyses revealed that increased skill acquisition and greater change in …

Target Cell-Associated Cd47 Suppresses Nadph Oxidase Activity In Macrophages During Antibody Dependent Cellular Phagocytosis, Seuly Akter

Electronic Theses and Dissertations

CD47-SIRPα signaling is a well-known immune checkpoint that suppresses macrophage-mediated antibody-dependent cellular phagocytosis (ADCP). In this study, we explored how CD47 influences reactive oxygen species (ROS) production driven by Fcγ receptor (FcγR) signaling. Our results show that macrophages produce significantly more ROS when encountering IgG coated target cells lacking CD47.Polarization with IFNγ further amplified this effect. ThusCD47-SIRPα interactions limit phagocytosis and suppress oxidative ROS production by macrophages. We found that CD47 blockade and IFNγ stimulation enhanced ADCP through distinct mechanisms. CD47 blockade removed the inhibitory "don't eat me" signal supporting ADCP and ADROS. Similarly, IFNγ enhances ADCP by upregulating FcγRI …

The "Not Seen" Effect Of International Financial Centers: Innovation In The Global Financial Ecosystem, Charlotte Ku, Andrew P. Morriss

South Carolina Journal of International Law and Business

International Financial Centers (IFCs) are hubs of legal and financial innovation, developing specialized frameworks that facilitate cross-border investment, enhance global capital mobility, and support economic growth. Through jurisdictional competition, professional clustering, and adaptive regulatory frameworks, IFCs have pioneered legal structures that enable enterprises of all sizes to participate in the global economy. Using case studies of the International Business Company, the Limited Liability Company, the Protected Cell Company, and advances in trust law and applying the theoretical frameworks of social scientist Richard Florida and psychologist Mihalyi Csikszentmihalyi, this article illustrates how IFCs serve as laboratories for financial experimentation, generating widely …

Physical Activity For Anxiety For Autistic People: A Systematic Review, Kathryn Riis, Brittany Samulski, Kristina A. Neely, Patricia Laverdure

Rehabilitation Sciences Faculty Publications

Clinical anxiety is a common comorbidity in autistic people. Due to the prevalence of anxiety in the autism population and the adverse effects it causes, there is a critical need to develop effective interventions which address anxiety symptoms for autistic people. Therefore, the purpose of this systematic review was to examine the effectiveness of the use of physical activity as an intervention to reduce anxiety in autistic people. Three databases PubMed, PsychInfo, and Cochrane RCTs, were searched utilizing key terms. PRISMA systematic search procedures identified 44 studies meeting predetermined inclusion criteria. Participant characteristics, the type of physical activity performed, the …

Newly Credentialed Athletic Trainers' Onboarding Process During The Transition To Practice, Ashley B. Thrasher, Stacy E. Walker, Julie M. Cavallario

Rehabilitation Sciences Faculty Publications

Context: As new athletic trainers (ATs) transition into their roles, some employers provide orientation and onboarding to assist with the transition to practice. Research in which authors outline the ideal onboarding process for new ATs transitioning to practice is lacking.

Objective: To examine the onboarding process for new ATs.

Design: Grounded theory.

Setting: College or university, secondary school, and hospital or clinic.

Patients or other participants: Seventeen newly credentialed, employed ATs who recently graduated from professional masters' programs (11 female, 6 male; 25.6 ± 2.2 years) and 12 employers (6 female, 6 male; years in role supervising new ATs: 8.5 …

'I Did Not Know We Could Exercise This Small Premature Baby': Challenges Experienced By Parents While Implementing Early Intervention For Their Preterm Infants-A Qualitative Perspective, Manasa Kolibylu Raghupathy, Selim Jahangir, Sonia Khurana, Leslie Edward S. Lewis, Bhamini Krishna Rao

Rehabilitation Sciences Faculty Publications

Background

Preterm birth is a highly stressful experience for both parents and infants. Parental participation in care enhances developmental outcomes, fosters parent-infant interactions and builds parental confidence. However, low parental adherence has always been a challenge in the successful implementation of intervention programs both in the NICU and at home. It is imperative to understand parents' perspectives and view the challenges that they experience through their lens while providing early intervention to their infants born preterm. This study is aimed at identifying new parents' challenges when implementing early intervention programs for their infants during the transition from hospital to home. …

Optimization Of Serum And Salivary Cortisol Interpolation For Time-Dependent Modeling Frameworks In Healthy Adult Males, Nathaniel T. Berry, Travis Anderson, Christopher K. Rhea, Laurie Wideman

Rehabilitation Sciences Faculty Publications

Cortisol is an important marker of hypothalamic-pituitary-adrenal function and follows robust circadian and diurnal rhythms. However, biomarker sampling protocols can be labor-intensive and cost-prohibitive. Objectives: Explore analytical approaches that can handle differing biological sampling frequencies to maximize these data in more detailed and time-dependent analyses. Methods: Healthy adult males [N = 8; 26.1 (±3.1) years; 176.4 (±8.6) cm; 73.1 (±12.0) kg)] completed two 24 h admissions: one at rest and one including a high-intensity exercise session on the cycle ergometer. Serum and salivary cortisol were sampled every 60 and 120 min, respectively. Six alternative sampling profiles were defined by downsampling …

Clinician Perspectives On Virtual Reality Use In Physical Therapy Practice In The United States, Danielle T. Felsberg, Jared T. Mcguirt, Scott E. Ross, Louisa D. Raisbeck, Charlend K. Howard, Christopher K. Rhea

Rehabilitation Sciences Faculty Publications

The primary goal of physical rehabilitation is to assess movement impairments and restore function to improve overall quality of life. Virtual reality (VR) may provide the optimal environment to promote these goals due to its motivating and modifiable nature which can be difficult to accomplish through traditional real-world therapeutic methods. Current research of VR for rehabilitation has demonstrated that VR interventions can produce clinically meaningful change in motor outcomes. Despite this, adoption and usage of VR by physical therapy professionals is unclear due to the limited research in this area. Thus, the purpose of this study was to identify the …

Salary Negotiation Dynamics For Athletic Trainers: Insights From Employers On Expectations And Organizational Influences, Julie M. Cavallario, Forrest Andrews, Kendallyn Johnson, Katherine Schalk, Cailee E. Welch Bacon

Rehabilitation Sciences Faculty Publications

Context

While researchers have previously identified that most athletic trainers (ATs) do not negotiate their salary, little is known about employers' expectations and behaviors relative to establishing and negotiating salaries for the ATs they hire.

Objective

To examine employers' expectations and behaviors regarding AT salary negotiation.

Design

Cross-sectional.

Setting

Web-based survey.

Patients or other participants

413 employers who are in a role that requires them to negotiate salary offers with prospective AT employees and who have minimally hired one AT into the organization they work for accessed the survey from a random sample of 7,000 ATs (6% access rate); 324 …

Perceptions Of Leadership Opportunities And Effectiveness Among Athletic Trainers: A Comparison Across Racial And Ethnic Groups, Nicolette A. Harris, Americus H. Williams, Julie M. Cavallario, Cailee E. Welch Bacon

Rehabilitation Sciences Faculty Publications

Context

Diverse representation in athletic training leadership is essential for fostering inclusion and innovation in the profession. Despite efforts to enhance leadership diversity, disparities persist, underscoring the need to explore barriers to leadership and the effectiveness of leadership in meeting the needs of athletic trainers (ATs).

Objective

To examine racial and ethnic differences in ATs' desire, pursuit, and attainment of leadership positions in the profession in addition to perceptions of current leadership effectiveness.

Design

Cross-sectional, web-based survey.

Participants

A purposeful sample of 1,173 racially and ethnically diverse ATs from an organized professional network followed by a random sample of 6,000 …

Case Report: Multifactorial Intervention For Safe Aging In Place, Ashwini Kulkarni

Rehabilitation Sciences Faculty Publications

Background/Objectives: Falls are a leading cause of morbidity in older adults, particularly those with multiple comorbidities. A multidisciplinary approach addressing physical, psychological, and environmental factors is essential for reducing fall risk and supporting aging in place. This report evaluates the effectiveness of a multidisciplinary, multifactorial approach in managing high fall risk in an older adult with diabetes, hypertension, and osteoporosis. Methods: A 72-year-old woman with a recurrent history of falls participated in an 8-week intervention as part of the American Physical Therapy Association (APTA) balance and falls prevention credential program. This study was conducted in Virginia Beach, USA, at the …