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An Observational Study On The Clinical Profile, Management Approaches, And Outcomes Of Adult Patients Admitted To The Intensive Care Unit For Status Epilepticus, Hasan M. Al-Dorzi, Eman Balahmar, Razan A. Almulhem, Raghad A. Almutairi, Danah H. Aleesa, Dareen S. Ashgar, Nazish Masud

Neurosciences

ABSTRACT Objectives: Status epilepticus (SE) is a serious neurological condition with a high risk of complications and mortality. We described adult patients who required admission to the intensive care unit (ICU) for SE and assessed their prognosis. Methods: We retrospectively analyzed consecutive adult ICU admissions for SE between 2016 and 2021. We performed multivariable logistic regression to determine the predictors of an unfavorable outcome (discharge Glasgow Coma Scale <14 or death). Results: We studied 115 patients (median age 38 years; males 62.6%; prior antiepileptic therapy 59.1%; median presenting Glasgow Coma Scale 7; median Status Epilepticus Severity Score 4). Brain computed tomography revealed acute/sub-acute stroke in 5.2% of cases, intracranial hemorrhage in 2.6%, and brain tumors in 5.2%. Cerebrospinal fluid analysis in 41 patients detected bacteria or herpes simplex virus in 4. Intravenous lorazepam was used to abort seizures in 80.0% of patients (median dose 3 mg). Mechanical ventilation was needed for 87 patients for a median of 4 days. Thirty-five patients (30.4%) experienced an unfavorable outcome, and hospital mortality was 5.2%. Infections present on admission were associated with an unfavorable outcome (odds ratio 3.61, 95% confidence interval 1.35-9.63). Conclusion: Most ICU admissions for SE involved young patients with few having abnormalities on brain imaging and cerebrospinal fluid and most needing intubation. Hospital mortality was 5.2% with the presence of an infection on admission linked to an unfavorable outcome.

Quality Of Life, Depression, And Anxiety In Brain Tumor Patients Following Surgical Resection At A Tertiary Care Center, Mohammed H. Bogari, Jalal A. Zahhar, Alwaleed K. Aloufi, Omar H. Algahtani, Yossef A. Zahhar, Hussin M. Kheshaifati, Abdulhadi Y. Algahtani

Neurosciences

ABSTRACT Objectives: To address the gap in understanding post-surgical quality of life, depression, and anxiety among brain tumor patients in Saudi Arabia. Methods: This cross-sectional study was conducted at King Abdulaziz Medical City in Jeddah, Kingdom of Saudi Arabia. A total of 160 adult brain tumor patients who underwent surgical resection between January 2021 and October 2024 were included. Quality of life (QoL) was assessed using the Functional Assessment of Chronic Illness Therapy (FACIT) questionnaire, and anxiety and depression were measured using the Hospital Anxiety and Depression Scale (HADS). Results: Among the 160 patients, high-grade gliomas were the most common …

Who Urges Action On Hepatitis, Announcing Hepatitis D As Carcinogenic

Neurosciences

No abstract provided.

Breastfeeding In Indonesia On The Rise, But Mothers Need More Support

Neurosciences

No abstract provided.

Editorial Message

Neurosciences

No abstract provided.

Comment On: When Assessing The Risk Of Cerebral Edema After Aneurysm Clipping, All Contributing Factors Must Be Taken Into Account

Neurosciences

No abstract provided.

Does Work-Related Stress Compromise Cardiovascular Health?

Neurosciences

No abstract provided.

Risk Factors, Clinical Characteristics, And Outcomes Of Perinatal Stroke In A Tertiary University Hospital, Shaden S. Alfayez, Muddathir H. Hamad, Amal Y. Kentab, Ahmad A. Alanezi, Daniah M. Kurdi, Hanady A. Almuhideb, Fahad A. Bashiri

Neurosciences

ABSTRACT Objectives: To investigate the risk factors, clinical characteristics, and neurodevelopmental outcomes associated with perinatal stroke, as well as to assess the risk of epilepsy, seizure control, and cognitive function in children with perinatal stroke. Methods: Data from 32 patients diagnosed with perinatal stroke between October 2007 and October 2020 were retrospectively reviewed. Results: Of 32 patients, 27 were born after normal pregnancies, and 20 (62.5%) had consanguineous parents. Family histories of stroke, haematological disease, and epilepsy were noted in 3.13%, 3.13%, and 21.88%, respectively. Initial symptoms included hemiparesis (56.25%), seizures (37.5%), respiratory distress (3.13%), and tiptoe walking (3.13%). Epilepsy …

Impact Of Qihuang Needle Therapy Combined With Flunarizine Hydrochloride For Vertigo In Vestibular Migraine, Dan-Ping Chen, Chao-Jie Yang, Zhong-Xing Peng, Zhi-Hua Zhou, Rong-Jiao You, Xin-Yu Li, Ai-Qun Liu, Zhen-Hu Chen

Neurosciences

ABSTRACT Objectives: To evaluate the impact of QHN combined with FH versus FH monotherapy on vestibular migraine (VM) Methods: The study included patients treated for VM with either QHN+FH or FH alone between September 2022 and September 2023 at The First Affiliated Hospital of Guangdong Pharmaceutical University in Guangzhou, Guangdong Province, China. The primary outcome was the change of Dizziness Handicap Inventory (DHI) before and after 8 weeks of treatment. Secondary outcomes included changes in the Video Head Impulse Test (v-HIT) results before and after 8 weeks of treatment, and the recurrence of vertigo attacks at 4 and 8 weeks …

Beyond Seizures: The Hidden Burden Of Fatigue In Epilepsy, Alia Mr. Fallatah, Malak R. Albadrani, Sarah A. Alsalman, Weam K. Almasuad, Abdulrahim M. Hamhom, Sumayah M. Almarshedy, Faisal A. Alsallom, Fawzya A. Bamogaddam, Majed H. Alhameed, Mubarak M. Aldosari

Neurosciences

ABSTRACT Objectives: To determine the prevalence of fatigue and depression in patients with epilepsy (PWE), explore their relationship, and identify the factors associated with fatigue in this population. Methods: This retrospective cross-sectional study involved adult PWE at King Fahad Medical City, Riyadh, Saudi Arabia, from April to July 2023. The Arabic version of the Fatigue Severity Scale questionnaire was used to estimate the presence and severity of fatigue. The Patient Health Questionnaire-9 was used for screening depression. The demographic and clinical data of the patients were analyzed. Results: In total, 259 PWE were enrolled. Of these, 66.8% had focal epilepsy …

Genetic Profile Of Charcot-Marie-Tooth Disease In The Saudi Population: A Retrospective Study Highlighting The Role Of Consanguinity, Aiman S. Alhazmi, Areej A. Alhareeri, Ali S. Alhawas, Essam W. Jameel, Faisal S. Aleisa, Muteb M. Alqahtani, Mutrik J. Almughni, Mohammed A. Almuqbil

Neurosciences

ABSTRACT Objectives: To identify the genetic landscape of CMT in Saudi Arabia. Methods: This retrospective cohort study included 43 patients diagnosed with CMT between 2016 and 2022 at National Guard Health Affairs hospitals in three cities. All CMT cases with a genetic diagnosis were included. Results: Genetic testing was conducted in 23 out of 43 CMT cases (53%), and clinically relevant genetic variants associated with CMT were identified in 17 of 23 patients (73.9%). The most common genes in the cohort were MTMR2 , PMP22 , and FGD4 , with notable intra-tribe mutations suggesting a strong influence of consanguinity. The …

Ajwa Date Extract (Phoenix Dactylifera L.): Phytochemical Analysis, Antiviral Activity Against Herpes Simplex Virus-I And Coxsackie B4 Virus, And In Silico Study, Ahmad K. Aljohani, Nader A. Maghrabi, Osama M. Alrehili, Abdulaziz S. Alharbi, Rawad S. Alsihli, Abdulrahman M. Alharthe, Rayan S. Albladi, Khalid A. Alosaimi, Bader M. Albadrani, Samar F. Miski, Hossein M. Elbadawy, Bandar D. Alrehaili, Fahd A. Abdelkarem, Modather F. Hussein

Saudi Medical Journal

Objectives: To investigate the phytochemical composition of Ajwa date extract and evaluate its antiviral activity and mechanism of action. Methods: High perfomance liquid chromatography, gas chromatography-mass spectrometry, and liquid chromatography-mass spectrometry were used to analyze the phytochemical profile of Ajwa date extract. The antiviral activity was assessed using the MTT colorimetric assay against herpes simplex virus type I (HSV-I) and coxsackievirus B4 (CVB-4). Assessment of the mechanism of action against HSV-I was carried out using 3 protocols. Molecular docking and quantum chemical calculations were carried out to predict the binding affinities of the identified compounds to viral glycoprotein D. Results: …

Impact Of Urgent Care Centers On Emergency Department Visits In Al Madina Al Munawara: A Pre-Post Study, Ahlam A. Aljohani, Jehan M. Alhazmi, Osama H. Alsaedi, Ahmed F. Al-Ahmadi, Noura S. Alshammary

Saudi Medical Journal

Objectives: To evaluate the impact of UCCs on reducing non-urgent Emergency Department (ED) visits and improving patient flow, focusing on metrics such as door-to-doctor time, doctor-to-decision time, and overall patient disposition. Methods: This observational cohort pre-post study analyzed data from 198,050 ED visits to King Fahad Hospital, Al Madina Al Munawara between June 2021 and May 2023 and compared visit patterns before and after UCC implementation. Results: Post-UCC implementation, the average door-to-doctor time decreased but was not statistically significant. Significant reductions were observed in doctor-to-decision and door-to-disposition times for CTAS 3 patients. However, overall patient flow improvements were not fully …

Graduate Catalog, Georgia Southern University

Graduate Catalogs

No abstract provided.

Trigger Factors And Intervention Strategies Of Information Addiction Among College Students: An Analysis From The Perspective Of Stimulus-Organism-Response(S-O-R) Theory, Chen Zhang, Weihan Jiang, Pengbo Qian

Journal of Scientific Information Research

[Purpose/significance]This study aims to explore the influencing mechanisms of information addiction behavior among college students, providing valuable reference for the prevention and management of information addiction behavior among college students. [Method/process]The Stimulus-Organism-Response (S-O-R) theory is introduced,and the external stimuli in the process of college students' information addiction are summarized through literature review. The cognitive psychology that arises in the addiction process of the body is deeply analyzed, and the theoretical model of college students' information addiction behavior is constructed. The trigger path of college students' information addiction is empirically analyzed using structural equation modeling. [Result/conclusion]Based on the research results, information …

Measles Cases Surge Worldwide, Infecting 10.3 Million People In 2023

Neurosciences

No abstract provided.

“Remember, You Are Not A Superhuman”: The Lived Experience Of Rest, Unrest, And Leadership In Special Operations, Trey Zoda

Dissertations

U.S. special operations forces (SOF) operate in volatile, uncertain, complex, and ambiguous (VUCA) environments that demand cognitive clarity, emotional regulation, and relational presence. While previous research on SOF readiness has addressed physical fitness, resilience, and sleep, little attention has been given to the psychological dimensions of rest and their implications for leadership. The purpose of this qualitative, transcendental phenomenological study was to explore the lived experiences of psychological rest and unrest in U.S. government SOF and the perceived influence of these states on their leadership. Guided by Moustakas’s transcendental method, in-depth, semi-structured interviews were conducted with SOF personnel. They were …

The Bioremediation Of Nutrients And Heavy Metals In Watersheds: The Role Of Floating Treatment Wetlands, Nirmal Kumar, Bhupinder Singh, Yuanze Chen, Abishek Kafle, Ram L. Ray, Sandeep Kumar, Xiaonan Shan, Venkatesh Balan

Civil & Environmental Engineering Faculty Publications

Floating treatment wetlands (FTWs) are engineered systems that utilize floating platforms planted with aquatic vegetation to treat polluted water such as stormwater, agricultural runoff, and wastewater. FTWs have emerged as promising and environmentally sustainable solutions for water purification. This review synthesizes the current knowledge on FTW design, plant selection, and performance evaluation. It highlights key factors influencing nutrient and heavy metal removal, including the hydraulic retention time, mat thickness, and types of plant species. Recent findings on the roles of root architecture, microbial interactions, and seasonal variability in treatment efficiency are also discussed. Additionally, the review explores advanced analytical methods …

Dentistry And The Law: The Difference Between ‘Non-Covered’ Vs. ‘Disallowed’ Services, Daniel Schulte Jd

The Journal of the Michigan Dental Association

The article clarifies the distinction between "non-covered" and "disallowed" services in dental plan audits. Non-covered services are not included in the patient’s dental plan, often due to plan limitations, while disallowed services are covered but deemed non-payable due to issues like claim deficiencies or lack of documentation. Dentists must review their contracts to understand obligations regarding non-covered services and ensure compliance with HIPAA for patient-paid services. For disallowed services, contesting decisions may be possible depending on the agreement with the dental plan.

Staff Matters: Why Are Our Employees Leaving? And How Do We Keep Them?, Jodi Schafer Sphr, Shrm-Scp

The Journal of the Michigan Dental Association

The article addresses the challenges of staff attrition in dental practices, emphasizing its costly impact and the need to understand its causes. Common reasons for attrition include low compensation, high workloads, poor management practices, and lack of career development opportunities. Solutions involve gathering feedback through exit interviews, improving salaries and benefits, balancing workloads, enhancing management styles, and offering career growth. Proactive measures can help retain staff and create a stable, supportive work environment.

Mda Foundation: Great Things Are Ahead For The Mda Foundation In 2025, Anne Berquist

The Journal of the Michigan Dental Association

The MDA Foundation expresses heartfelt gratitude to donors and volunteers who contributed to improving oral health care access and education in 2024. Efforts included funding free and reduced-cost clinics, awarding scholarships, and hosting the Mission of Mercy (MOM) free clinic in Flint. For 2025, plans include the Sparkling Smiles fundraising event during the MDA Annual Session in Detroit and laying the groundwork for next year’s MOM in Kalamazoo. The Foundation encourages applications for grants (deadline: May 1) and scholarships (applications open Aug. 1), continuing its commitment to supporting Michigan communities and dental students.

Sir Fig Newton And The Science Of Persistence (2023) By Sonja Thomas, Maughn Rollins Gregory

Middle Grades Books

When twelve-year-old Mira Williams’s companion and confidant, the cat Sir Fig Newton, contracts diabetes, her parents say she may have to give him to someone who can afford his treatment. The resources Mira will need to save Fig and keep him close include ingenuity, family ties, friendships, and the kind of faith she finds can be compatible with science. Thomas’ novel shows a teenager’s sophisticated engagement with complex questions of race, faith, science, and relationships.

Do Educators Recognize Student Struggles? Mental Health Perceptions And Knowledge In Biology, Kanza Arshad, Stephanie Drendel, Nicole Scheuermann

CURE Proceedings

No abstract provided.

The Effects Of Multiplanar High Intensity Resistance Training On Increasing Bone Mineral Density On Middle Aged Females. The Stop Protocol, Ava Krall, Matthew J. Herring, Elise Craven, Rachel A. Kowal, Peter J. Chomentowski, Brandon Male, Ethan Darley, Clayton L. Camic

CURE Proceedings

No abstract provided.

Association Between Rurality And Race/Ethnicity And Pediatric Cancer Early Mortality: A Population-Based Cohort Study Using Seer Data From 2000 To 2021, Kiersten Preuss, Emma Hymel, Melissa Acquazzino, Shinobu Watanabe-Galloway

Journal Articles: Epidemiology

BACKGROUND: Pediatric cancer mortality rates have steadily declined since 2009, but over a thousand deaths still occur annually. While existing research highlights the effects of race/ethnicity and rurality on overall survival, few studies have specifically analyzed these factors in relation to early mortality, defined as death within 12 months of diagnosis.

PROCEDURE: This study utilized SEER Research Plus Limited-Field Data (2000-2021) to examine the association between race/ethnicity, rurality, and early mortality in pediatric cancer patients. A cohort of 138,648 individuals was analyzed using Cox proportional hazards regression models to calculate hazard ratios and 95% confidence intervals (CIs).

RESULTS: The results …

Integrating Human And Animal Health In The Stop Spillover Outbreak Scenarios, Kathleen E. Angell, He Julia Bai, Katherine C. Prager, Janetrix H. Amuguni, Felicia B. Nutter, Jonathan D. Gass Jr, David Brett-Major

Journal Articles: Epidemiology

OBJECTIVES: To generate and employ scenarios of sentinel human and animal outbreak cases in local contexts that integrate human and animal health interests and practices and facilitate outbreak risk management readiness.

METHODS: We conducted a scoping review of past outbreaks and the strengths and weaknesses of response efforts in USAID STOP Spillover program countries. This information and iterative query-and-response with country teams and local stakeholders led to curated outbreak scenarios emphasizing One Health human:animal interfaces at sub-national levels.

RESULTS: Two core scenarios were generated adapted to each of 4 countries’ pathogen priorities and workflows in Africa and Asia, anchoring on …

Schistosoma Haematobium Infection And Associated Risk Factors Among Pre-School Age Children In Gambella, Ethiopia, Tigist Mohammed, Abraham Degarege, Mulugeta Aemero, Abebe Animut, Yohannes Negash, Yirgalem Gebrehiwot, Berhanu Erko

Journal Articles: Epidemiology

Background

Method

International Society Of Sports Nutrition Position Stand: Β-Hydroxy-Β-Methylbutyrate (Hmb), John A. Rathmacher, Lisa M. Pitchford, Jeffrey R. Stout, Jeremy R. Townsend, Ralf Jäger, Richard B. Kreider, Bill I. Campbell, Chad M. Kerksick, Patrick S. Harty, Darren G. Candow, Brandon M. Roberts, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Douglas S. Kalman, Jose Antonio

Faculty Publications

Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on an analysis of the literature regarding the effects of β-Hydroxy-β-Methylbutyrate (HMB). The following 12 points have been approved by the Research Committee of the Society: 1. HMB is a metabolite of the amino acid leucine that is naturally produced in both humans and other animals. Two forms of HMB have been studied: Calcium HMB (HMB-Ca) and a free acid form of HMB (HMB-FA). HMB-FA appears to lead to increased appearance of HMB in the bloodstream when compared to HMB-Ca, though recent results are mixed. 2. …

Correspondence, To Abe D. Waldauer From Jere L. Crook, 1934 June 5

Documents

Correspondence, to Abe D. Waldauer, Memphis, TN, from Jere L. Crook, The Crook Sanitorium, Inc., Jackson, TN, 1934 June 5. Crook is giving Waldauer a health update on one of Waldauer's clients. Crook leaves a P.S. note, "Are you obeying instructions I gave you? You cannot live on lettuce & spinach. You are neither a rabbit nor a squirrel. Hope you are eating & sleeping well. JLC."

How Do Patient-Provider Relationships Affect Patient Satisfaction?, Rose D. Lightspeed

Anthós

This article reviews studies on patient satisfaction within the U.S. healthcare system to investigate how physicians’ behavior influences patients’ reported quality of care. Medical negligence, neglect, and cognitive biases are identified from the reviewed literature as physician behaviors that affect the patient-provider relationship and patient satisfaction. Emphasizing patient satisfaction and involvement in their care as important considerations when evaluating patient-provider relationships, Lightspeed underscores how the complex dynamic between patient and provider–including physicians’ reported feeling of inadequate interpersonal skills and patients’ sensitivity to dismissive communication–contributes to reduced satisfaction rates. Lightspeed argues that increasing physician awareness of these factors that influence patient …