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Career And Technical Education: Evaluating The Benefits Of Partnerships Among Schools And Organizations, Rosalynn Tennie

Doctor of Education Dissertations

Employers are experiencing skill gaps when hiring employees. Employability skills are taught in high school through Career and Technical Education (CTE) courses. High school students receive hands-on experience through work-based learning opportunities such as internships with the help of organizations in the community. The partnership between schools and organizations is vital to the success of internships. This study investigated the lived experiences of organizations that offered internships to high school students. The study focused on a school district in the northeastern central region of North Carolina. The primary method of data collection used in the study was interviews. The interviews …

A Mentoring Program's Impact On International Teachers In A Rural School District, Shannon M. Hullett

Doctor of Education Dissertations

This dissertation is a program evaluation of a mentoring program’s impact on international teachers in a rural school district. The study aimed to investigate international teachers' first-year mentoring experiences to determine if the program has an impact on helping international teachers transition to the community and school. Acculturation theory (Berry, 1980; Bunnell, 2020; Stasel, 2021) and culture shock (Oberg, 1960; McCluskey, 2020) were identified as theoretical frameworks for the program evaluation. Quantitative data were collected from surveys and mentor log rubric analysis, and qualitative data were collected from interview transcripts. According to data analysis, the program had a significant impact …

The Power Of Church Leadership Training And Development: Equipping, Empowering, And Encouraging Church Leaders To Lead Effectively, Monique Kirk

Doctor of Education Dissertations

This study explored perceptions of a church’s ministry leadership team to determine their preparation in the tools, skillsets, and strategies needed to lead themselves and others well. The study sought to understand the needs of these church ministries to meet the spiritual and daily needs of the members they serve. The study used a mixed methods design, employing a survey and focus group that examined perceptions of ministry experiences, training, development, and other support. Results were examined through the lens of Lewin’s (1947) force field analysis to determine both driving and restraining forces on effective ministry leadership (Hussain et al., …

The Implications Of Student-Centered Design On High School Dropout: The Experience Through The Lens Of Students At-Risk Of Dropping Out, Angela R. Alford

Doctor of Education Dissertations

This qualitative study explores the implications of Student-Centered Design on high school completion, particularly for students identified as at risk of dropping out. Grounded in the theory of Student-Centered Design, this research examines how this approach serves as a scaffold for collaborative problem-solving in secondary education and addressing real-world challenges faced by students at-risk of dropping out.

The study uses a qualitative methodology, utilizing a survey and a focus group to gain insight from former students who experienced Student-Centered Design, as well as educators who implemented this approach. By analyzing participant feedback, the research evaluates the effectiveness of Student-Centered Design …

Perception Of Middle School Counselors About How To Increase The Enrollment Of Minority Students, Specifically African American And Hispanic, In The Health Science Curriculum At Empire High School, Charles S. Robertson

Doctor of Education Dissertations

This study explored the perceptions of middle school counselors regarding strategies to increase enrollment of minority students, specifically African American and Hispanic, in the health science curriculum at Empire High School. Utilizing a mixed methods convergent parallel design, this research integrated both quantitative and qualitative data to provide a comprehensive understanding of counselor viewpoints, existing barriers, and potential solutions. Lewin’s Change Model, as outlined by Burnes (2019), provided the theoretical framework for the analysis, guiding it through the stages of unfreezing existing mindsets, implementing change, and refreezing new practices. Quantitative data were collected via surveys administered to middle school counselors …

A Phenomenological Exploration Of Students' Perceptions Of Social-Emotional Factors In Teacher-Student Relationships And Its Impact On Academic Achievement Of Impoverished High School Youth, Jeannine L. Carrington

Doctor of Education Dissertations

This phenomenological study explored the experiences of former students from a Title I high school in a disadvantaged urban community, focusing on how socio-emotional factors in teacher-student relationships influenced academic achievement. Grounded in Bandura’s (1977) social learning theory and the CASEL (2017) social-emotional learning (SEL) framework, the study examined how teacher encouragement, emotional support, and expectations impacted student motivation and persistence. Twenty alumni participated in semi-structured interviews, analyzed using Braun and Clarke’s (2006) thematic analysis. Five themes emerged: teacher encouragement, emotional support, high expectations, cultural awareness, and long-term impact. Findings suggest that emotionally supportive, trusting relationships foster self-efficacy, engagement, and …

Solutions To Building Consistent And Sustainable Youth Ministry Programming, William C. Kincy

Doctor of Education Dissertations

This mixed methods convergent study explored strategies for building consistency and sustainability in Baptist youth ministry programming, with a particular focus on the AFC Youth Ministry. Guided by Maslow’s Hierarchy of Needs (Hitt et al., 2018) and Senge’s (2006) Systems Thinking approach, the study addressed three key research questions: What needs are youth seeking to meet that lead them to join a Baptist church youth ministry? What programming can AFC Baptist Church’s youth ministry provide to youth that would promote retention of the youth in the youth ministry? What are the best practices in delivering programming to youth in a …

Exploring Teacher Perceptions And Implementation Factors Influencing Career Development Plan Completion In Middle Grades: A Study Of The Majorclarity Platform, Keri Marie Brewer

Doctor of Education Dissertations

This qualitative study investigated the implementation fidelity, teacher perceptions, and contextual factors influencing the use of the MajorClarity career readiness platform to support career development plan (CDP) completion among middle grade students in a North Carolina school district. Guided by Bandura’s (1986) Social Cognitive Theory and Darling-Hammond et al.’s (2001) Learning Theory, the study explored how instructional strategies, training quality, leadership support, and systemic barriers shape program outcomes. Data were collected through two rounds of semi-structured interviews with six Career and Technical Education teachers, using inductive thematic analysis to identify patterns across participant responses. Findings revealed that while educators recognized …

Teacher Perceptions Of Social-Emotional Learning In A Covid-Impacted Environment, Gina Gold

Doctor of Education Dissertations

Social-emotional learning (SEL) builds students’ resilience skills, which impact the biology of the brain connected to emotional regulation, safe behaviors, and positive learning outcomes. Diminished resilience is typically the result of childhood trauma, which affects physical and emotional health into adulthood. Teachers’ capacity, implementation, and data analysis practices for SEL are important to support building resilience skills in our students to help them grow to be emotionally and physically healthy citizens. The purpose of this research study was to investigate the perspectives of elementary school teachers from four elementary schools in the same school district in rural, southwestern North Carolina …

A Phenomenological Study On How White Public Middle School Teachers Who Self-Identify As Racial Allies Experience And Navigate Their Implicit Biases, Joyce Faye Patton

Doctor of Education Dissertations

The teaching force in the United States is overwhelmingly White, while the student population is increasingly diverse, reaching a minority majority in 2014. The racial mismatch between a predominantly White teaching force and students of color in public schools presents barriers for those students as they navigate an educational system built on historical injustices and racism. The study examines the lived experiences of White middle school teachers who identify as racial allies in schools having a student population that is greater than 50% students of color. The interviews revealed that participants understood bias on a basic level yet continued to …

Teacher And Parent Perspectives Of Young Children's Development Since The Covid-19 Pandemic In A Rural Public School District, Regina L. Lineback

Doctor of Education Dissertations

Face to face education for young children was interrupted in March of 2020 due to mandatory school closures precipitated by the COVID-19 pandemic. Virtual learning was forced upon teachers and students at a time when many families and teachers had limited or no access to internet. When face to face learning resumed, teachers and students were required to wear facial masks and maintain social distancing protocols. This study sought to explore teacher and parent perspectives of young children’s development in a rural public school district since the COVID-19 pandemic. A qualitative study was completed using teacher interviews, a teacher focus …

Epidemiologic And Immunologic Characterization Of The Post-Acute Sequelae Of Covid-19, Christine Marie Miller

Yale Graduate School of Arts and Sciences Dissertations

Since its emergence in late 2019, SARS-CoV-2 has infected over 15 million people—and the number continues to rise. The global impact of this novel coronavirus has been profound, reshaping not only public health infrastructure but also our understanding of human biology. The full extent of the virus’s effects on the immune system remains incompletely understood and will likely take years to fully unravel. What is already evident, however, is that SARS-CoV-2 uniquely modulates both innate and adaptive immunity, with consequences that span the developmental spectrum—from fetal and pediatric stages through adulthood. While many individuals recover without overt clinical sequelae, an …

Glycolysis-Induced Acidification Links Mitochondrial Deficiency To Axon Degeneration, Hadas Dabas

Yale Graduate School of Arts and Sciences Dissertations

Axons extend far from the neuronal soma and depend on local energy metabolism to sustain signaling and structural integrity. Mitochondria are normally abundant in axons, where they provide numerous utilities. In many neurodegenerative diseases, however, mitochondrial function or trafficking is impaired, but the mechanisms linking mitochondrial loss to axon degeneration remain unclear.In this dissertation, I use C. elegans mitochondrial trafficking mutants, in which axons completely lack mitochondria, to define the metabolic basis of degeneration. I find that glycolysis, typically viewed as a protective energy source, unexpectedly promotes axon breakdown. Elevated glycolytic flux in axons without mitochondria leads to accumulation of …

Associations Between Mental Health Conditions And Adverse Pregnancy Outcomes Among Active-Duty Servicewomen, Laura Manzo

Yale Graduate School of Arts and Sciences Dissertations

Active duty servicewomen (ADSW) have increased risk for mental health conditions compared to civilian women. Civilian research demonstrates that women with mental health conditions experience serious pregnancy complications at rates 50% higher than those without mental health conditions. Although mental health conditions are the leading underlying cause of maternal mortality, there is limited research on the prevalence of perinatal mental health conditions among active duty servicewomen (ADSWs) or their association with adverse pregnancy outcomes. This study aimed to explore associations of mental health conditions and adverse pregnancy outcomes in a population of ADSW. Methods Department of Defense Birth and Infant …

Molecular Investigation Of Signaling Molecules Involved In Cerebrovascular Disorders, Kimberly Jean Vish

Yale Graduate School of Arts and Sciences Dissertations

The most common forms of cerebrovascular malformations are brain arteriovenous malformations (AVM), often caused by genetic mutations in the EphB4-p120RasGAP signaling pathway, and cerebral cavernous malformations (CCM), often caused by genetic mutations in the CCM signaling pathway. These pathways are well studied, but there are clear deficiencies in the molecular level understanding of how signals are transduced. Relevant to AVM, the GTPase activating protein (GAP) for Ras, p120RasGAP, is necessary for downregulating Ras signaling during vascular development, and loss of its activity is associated with impaired cerebrovascular development. In my thesis, I investigate how p120RasGAP uses its Src-homology 2 (SH2) …

Smart Synthesis: Harnessing Electrochemistry To Enhance Catalytic Water Treatment, Aidan Francis Meese

Yale Graduate School of Arts and Sciences Dissertations

Catalytic water treatment technologies hold great promise for degrading even the most recalcitrant contaminants of emerging concern (CECs). Heterogeneous catalytic processes are especially appealing, providing the benefits of easy catalyst recovery and reduced risk of secondary pollution. However, heterogeneous reactions often suffer from mass transfer limitations, and the development of catalyst materials that are sufficiently active, selective, and stable under the conditions necessary for pollutant degradation remains challenging. Furthermore, synthesis of catalyst materials, particularly those with desirable catalytic properties and novel architectures, are often time- and energy-intensive and involve expensive materials and/or equipment. In this work, we address these challenges …

Development Of The Human Brain Networks During Infancy, Huili Sun

Yale Graduate School of Arts and Sciences Dissertations

In early infancy, the human brain undergoes rapid network construction and remodeling. Advances in neuroimaging have made non-invasive, in-vivo observation of these brain changes possible during the perinatal period. However, how the brain develops to support dynamic activity and cognitive function remains unclear. In this thesis, I leverage the network control theory to model brain controllability - the capacity to drive activity changes - and examine its role in neurodevelopment. I first outline the developmental trajectories of controllability during the perinatal period and link them to synaptogenesis with cross-species models. Next, I introduce a machine-learning framework to explore how white …

A Dimensional Approach To Assessing The Effects Of Early-Life Stress On Mental Health Across Development, Emily Meryl Cohodes

Yale Graduate School of Arts and Sciences Dissertations

Decades of research inform our understanding of the pernicious effects of exposure to stress for individuals across the lifespan. This research underscores that exposure to stressful contexts places individuals at increased risk for developing cognitive, social, emotional, and physical health problems. However, exposure to stress does not have a universal effect on all individuals across development, likely due in part to the extreme heterogeneity in experiential, environmental, and temporal aspects of stress. Recent advances in the study of the psychobiological effects of stress have focused on better understanding how heterogeneity in exposure may account for heterogeneity in developmental and clinical …

An Ecological Approach For Understanding The Influence Of Threats In Youth’S Social Environments, May Isabella Conley

Yale Graduate School of Arts and Sciences Dissertations

A central question motivating developmental research for decades has been how threats in youth’s social environments influence development. In particular, researchers have focused on understanding how threats in different contexts in youth’s social environments increase risk for adverse outcomes and why some youth exposed to threats appear more susceptible to adverse outcomes than others. Increasingly, researchers have identified cognitive and neurobiological factors that are thought to contribute to youth’s susceptibility to threats. Despite these advances, our understanding of the influence of threats on development remains incomplete due to a few critical limitations. Notably, while foundational ecological theories emphasize youth’s social …

The Roles Of Terrestrial Weathering And Marine Bioturbation In Shaping Earth’S Surface Habitability Across Time, Brian Beaty

Yale Graduate School of Arts and Sciences Dissertations

The existence of life on Earth for over 3.8 billion years implies continuously habitable conditions despite major changes to the planet’s climate and surface geochemistry. In this thesis, I explore two Earth surface processes – terrestrial weathering and marine bioturbation – and their roles in shaping environmental habitability across various timescales. Weathering has long been recognized as a fundamental component of the Earth system. On multi-million-year timescales, it is the primary source for limiting nutrients to the biosphere and primary sink for atmospheric CO2. This concept underlies recent interest in artificially accelerating global weathering rates to mitigate near-future warming. However, …

Molecular Mechanisms Of Kras Regulation And Resistance In Pancreatic Ductal Adenocarcinoma, Xiangyu Ge

Yale Graduate School of Arts and Sciences Dissertations

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive human malignancies, with a five-year survival rate of less than 13%. Oncogenic KRAS mutations occur in over 90% of cases and drive tumor initiation and progression, making KRAS a desirable therapeutic target. Despite the development of direct KRAS inhibitors, clinical efficacy has been modest due to rapid adaptive resistance. This thesis primarily investigates the molecular mechanisms by which PDAC cells adapt to KRAS inhibition, while also uncovering co-vulnerabilities that can be therapeutically exploited. Chapter 1 provides a comprehensive literature review of KRAS biology in PDAC, summarizing historical and contemporary findings …

Vaccine-Induced Immunity: Insights Into Sars-Cov-2 And Orthopoxvirus, Valter Monteiro

Yale Graduate School of Arts and Sciences Dissertations

Emerging infectious diseases like SARS-CoV-2 and re-emergent pathogens such asmpox (formally known as monkeypox) have posed substantial challenges to global health, often due to immune escape and antigenic variability. My research addresses these challenges by evaluating and designing vaccine strategies to enhance immune responses and cross-protection, focusing on SARS-CoV-2 variants and members of the Orthopoxvirus family. The central aim of my research is to understand and overcome limitations in immune responses to antigenically variable pathogens. My studies focus on humoral responses to SARS-CoV-2 variants through targeted booster regimens, exploring cross-protective immunity in Orthopoxvirus vaccines, and testing new mRNA vaccines to …

Fine Particulate Air Pollution Exposure Burden And Sociodemographic Health Disparities In The United States: Impacts From Energy Transitions And Temporal Variation In Mortality Risk, Rory Stewart

Yale Graduate School of Arts and Sciences Dissertations

Climate change, the defining environmental crisis of our time, has been shown to impact concentration, distribution, and composition of tropospheric air pollutants, including particulate matter. Economic patterns greatly shape the generation of particulate matter as well as greenhouse gases that enhance climatic changes. Substantial evidence shows that exposure to fine particulates, particulate matter with aerodynamic diameter <2.5 µm (PM2.5), contributes to premature mortality and morbidity. These detrimental health outcomes have been shown to be experienced unequally across population groups, with disparities in the level of exposure and in the magnitude of health response for marginalized populations that have higher vulnerability to air pollution exposure. It is also possible that these health responses are not static, but dynamic over time due to changes in population health and composition of air pollution exposures, warranting deeper investigation into the directionality and shape of these health responses. Modeling potential future energy scenarios by using existing knowledge on health responses to air pollutants allows researchers and policymakers to understand how changes to air pollution can impact population health before policies are implemented. Thus, inclusion of appropriate modelling techniques and analyses of energy policy impacts is essential to understanding health impacts from climate mitigation and adaptation across population groups within the United States. This dissertation contributes to the growing knowledge base on climate mitigation, health co-benefits from air pollution concentration changes and health response changes across time to air pollution exposures. Chapter two presents work investigating whether energy policies that aim to reduce greenhouse gas emissions have a secondary impact of reducing health burden in the United States (U.S.) and if any changes to mortality and hospitalizations differ across subpopulations. I explored four future sector-specific energy policy scenarios (electrification of ports and marine shipping, low long-term natural gas pricing, high electric vehicle uptake, and innovations in building energy efficiency) and a business-as-usual scenario to determine how changes to ambient PM2.5 levels impact health within the continental U.S. by region, race/ethnicity, urbanicity, and income. I also investigated how methodological assumptions impact findings. I found projected avoided premature mortalities from energy transition policies range from 67,011 (95% CI: 45,692, 82,397) to 81,003 (55,286, 99,532) individuals in 2050 and 11,577 (1,332, 19,918) to 13,552 (1,560, 23,303) avoided cardiorespiratory hospitalizations in 2050, showing substantial health co-benefits from greenhouse gas mitigation policy implementation. These benefits vary by region and subpopulation, with Black, suburban, and less wealthy Americans experiencing the highest percent reduction in mortalities across all energy policy scenarios. Analysis into how population assumption specificity (such as using race-specific incidence rates instead of total population rates) influences the results proved that more specific population assumptions can make substantial differences to overall health projections. This research demonstrates the vast health benefits of climate mitigation strategies and how they differ across subpopulations, with some environmental justice populations benefiting more relative to the overall population. In chapter three, I investigated how PM2.5-mortality associations vary over time (2001-2016) in North Carolina and Michigan, while considering how temporality of these associations varies by sociodemographic variables. Results indicate that the direction of PM2.5– mortality health effects varies by location. The odds ratio (OR) for mortality per 10?g/m3 PM2.5 differed across time from 2001-2008 to 2009-2016, increasing by 0.28% in Michigan and decreasing 0.78% in North Carolina. Non-linear models show steadily increasing PM2.5-mortality odds over time for Michigan but an “S” shape for North Carolina. I also found suggestive evidence of widening disparities in PM2.5-mortality odds over time by age, race/ethnicity, urbanicity, sex, and education, although the magnitude of those changes varies across subpopulations and state. This research shows that mortality impacts of PM2.5 are changing over time, with different trends by location and subpopulation, potentially exacerbating environmental justice. This dissertation research underscores the importance of analysis to determine sociodemographic population health disparities when modeling co-benefits of energy and air pollution policies as overall estimates may obscure important differences across subpopulations. Better projections on local health effects on vulnerable communities can enhance equity considerations for climate mitigation actions, as well as provide a more holistic analysis on benefits of cost to implement versus avoided exposure and health costs. Further, this research shows that concentration-response functions may vary temporally and that such trends vary across location. This suggests that applications of historical concentration-response estimates may be obscuring the actual health impact on populations through over- or underestimates of health responses to a certain level of exposure. Improvements in the methodological assumptions of exposure and health response by introducing temporal variation provide researchers with a more accurate representation of the association between air pollution and health, which should be more widely considered in epidemiologic research. These results can inform policymakers and public health professionals in evaluating which communities are at highest risk from particulate exposures in the present day and into the future, especially in relation to temporal trends and projected changes in emissions, particulate composition, and population vulnerability.

Mental Health Disparities From Climate Change: Age Differences And Structural Drivers Across California, Elizabeth Choa

Yale Graduate School of Arts and Sciences Dissertations

Background: The health impacts of climate change are shaped by a complex interplay of geopolitical, ecological, and socioeconomic forces. Climate events impose substantial personal and societal costs, draining resources and deepening existing vulnerabilities within communities. Yet few studies examine how these dynamics affect groups often overlooked in climate–health discourse, including LGBTQ+ individuals, informal caregivers, and older adults. Objective: To examine how individual, community, and structural-level factors influence both climate vulnerability (defined as susceptibility to adverse health impacts) and climate resilience (the capacity to adapt to and withstand climate-related stressors). Focusing on diverse adult populations in California, this dissertation aims to …

Limbic Circuit Control Of Stress And Neuroinflammation, Alexa Renee Soares

Yale Graduate School of Arts and Sciences Dissertations

Individuals are constantly subjected to various forms of stress, which shape the brain in different ways. The brain, in turn, must coordinate a response to adapt to the demands of the stressor. This response is coordinated via interactions between several neuromodulatory and neuroinflammatory signaling pathways. The limbic system, particularly the amygdala and hippocampus, has been highlighted as an important site for integration of these signals. These areas are critical for engaging neural, autonomic, and behavioral responses to acute stress and for plasticity-driven learning that can shape future responses to stress through a process called allostasis. Chronic exposure to stress can …

Building Intelligent Robots For Social Regulation Therapy, Rebecca Ramnauth

Yale Graduate School of Arts and Sciences Dissertations

Throughout life, we learn the rules of social behavior by observing others, by exposure to diverse social contexts, and, in some cases, through targeted intervention. More than learning the rules and expectations on how to behave, social regulation involves the dynamic, real-time coordination of one's internal states and outward behaviors to meet those expectations. Regulation becomes challenging when internal states conflict with external demands, such as in moments of heightened emotion, sensory overload, or social ambiguity. In certain contexts (such as isolation during a global pandemic) or for some individuals (such as those with autism), social regulation can be difficult …

Reducing Dementia Risk By Identifying And Promoting Social Determinants: A Multi-Site And Multi-Method Study, Jose M. Aravena

Yale Graduate School of Arts and Sciences Dissertations

Background: Dementia is one of the leading causes of disability and death, and the most feared condition by older adults. Although encouraging evidence has shown that lifestyle can play a pivotal role in dementia prevention, dementia incidence is still increasing in those groups that are at most risk. A largely unexplored explanation for this phenomenon in high-risk groups is the effect of social determinants of health (SDH), a range of structural (i.e., social position, healthcare services) and psychosocial determinants (ageism, social perceptions of dementia) that can be a major modifiable driver of brain and cognitive health. Thus, by using three …

Neurocognition In Youth With Prediabetes, Jade Ivey Quillian

Yale Graduate School of Arts and Sciences Dissertations

The association between type 2 diabetes (T2D) and cognitive impairment has been well established. This is critical because T2D is a key risk factor for Alzheimer’s disease. However, these studies often fail to account for adiposity and other co-morbid conditions that accompany T2D in older adults. As a result, the mechanisms linking connecting T2D and cognitive impairment consequently remain unclear. The overall aim of this dissertation is to understand the precise effects of dysfunctional glucose metabolism on neurocognition. To do this I capitalized on a unique opportunity to study dysregulated glucose in youth from the Pathogenesis of Youth Onset Diabetes …

Exploring Communication In Pediatric Oncology And Parental Bereavement Outcomes: A Mixed Methods Study, Na Ouyang

Yale Graduate School of Arts and Sciences Dissertations

The first two years after a child’s death, defined by parents as early bereavement, are a particularly vulnerable period for parents. More than 40% of bereaved parents report severe, prolonged grief symptoms during early bereavement. High-quality parent-clinician communication, which is delivered honestly, clearly, and with sensitivity, helps parents make informed decisions about medical care, address their complex needs during their child’s end-of-life (EOL), and is related to lower severity of prolonged grief symptoms many years after a child’s death. However, research rarely focuses on the parent experience in early bereavement, and little is known about which specific components of parent-clinician …

Understanding The Double-Itcz Bias: From Ocean-Atmosphere Interactions To Future Climate Projections, Zhiyuan Li

Yale Graduate School of Arts and Sciences Dissertations

The double-ITCZ bias is one of the most persistent and long-standing model deficiencies in General Circulation Models (GCMs), affecting simulations of tropical precipitation patterns and future climate projections. This bias manifests as an unrealistic secondary Intertropical Convergence Zone (ITCZ) forming south of the equator, particularly in coupled ocean-atmosphere models. Since the ITCZ plays a crucial role in shaping global precipitation patterns, addressing this bias is essential for improving climate model reliability. CMIP6 projections indicate that the double-ITCZ feature may become more pronounced under global warming, raising the question of whether this enhancement represents a true climate change response or a …