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Constructing Women Who Do Not Reproduce In Global Neoliberalism: Critical Approach To The Abolition Of Legal Ban On Abortion And The Struggle In South Korea, Yumi Kwon Feb 2025

Constructing Women Who Do Not Reproduce In Global Neoliberalism: Critical Approach To The Abolition Of Legal Ban On Abortion And The Struggle In South Korea, Yumi Kwon

Dissertations, Theses, and Capstone Projects

This study historically examines the abolition of the legal ban on abortion and the struggle in South Korea, focusing on the construction of the status of “women who do not reproduce”, and accordingly aims to critically analyze how neoliberal reproductive crisis in South Korea has been reorganized into the new order through the constitutive role of the struggle.

The results of the analysis are as follows: First, by examining Fraser’s theory, I explain that when the “boundary” dividing the realms of production and reproduction is a place of contradiction and struggle, the phenomenon of women not reproducing is centrally located …


Evidence For Interactive Effects Of Inhibitory And Prospective Intolerance Of Uncertainty And Stimulus-Level Uncertainty On Threat Safety Discrimination Learning, Kyoko Yazaki Feb 2025

Evidence For Interactive Effects Of Inhibitory And Prospective Intolerance Of Uncertainty And Stimulus-Level Uncertainty On Threat Safety Discrimination Learning, Kyoko Yazaki

Dissertations, Theses, and Capstone Projects

Fear is a fundamental component of human learning, critical for survival, and extensively studied through Pavlovian conditioning paradigms (LeDoux & Pine, 2016). This thesis examines the interplay between stimulus-level uncertainty and individual differences in intolerance of uncertainty (IU) on threat-safety discrimination learning. Using a within-subject design, participants were conditioned to certain (100% reinforcement), uncertain (50% reinforcement), and safety (0% reinforcement) cues through the pairing of colored visual stimuli with aversive electrical shocks. Discrimination learning was assessed using both implicit (SCR) and explicit (self-reported US expectancy estimates and unpleasantness ratings) measures.

The present study (n = 102) replicated previous findings showing …


Beyond The Sum: A Network Analysis Of Adverse Childhood Experiences And Behavioral Outcomes In Justice-Involved Youth, Jennifer Yang Feb 2025

Beyond The Sum: A Network Analysis Of Adverse Childhood Experiences And Behavioral Outcomes In Justice-Involved Youth, Jennifer Yang

Dissertations, Theses, and Capstone Projects

This dissertation examines gender-specific patterns of adverse childhood experiences (ACEs) among justice-involved youth using network analysis. Despite experiencing higher rates of childhood adversity, female youth show lower recidivism rates than males, presenting an empirical paradox. Using a sample of 19,454 justice-involved youth (75% male), this study applies novel network methods to understand how ACEs and behavioral outcomes are organized across gender. Findings reveal distinct network architectures: female youth maintain more integrated but vulnerable networks, while males show more compartmentalized but stable structures. Female recidivists demonstrate systematic network destabilization when compared to non-recidivists, characterized by a 39% reduction in network density, …


Characterizing Malaria Infections In Caribbean Lizards: Parasite Niche Expansion & Host Response, Sarah J. Pangburn Feb 2025

Characterizing Malaria Infections In Caribbean Lizards: Parasite Niche Expansion & Host Response, Sarah J. Pangburn

Dissertations, Theses, and Capstone Projects

Malaria is historically one of the most severe parasitic human diseases and is still responsible for over half a million deaths annually. Plasmodium species, the causative agents of malaria, are often characterized by two hallmark features of their asexual stages: the invasion of vertebrate red blood cells and the presence of hemozoin pigment as a byproduct of host hemoglobin digestion. Despite their evolutionary relatedness to mammalian Plasmodium, wildlife malaria parasites are understudied, leaving their vast genetic diversity to be explored. Lizard-infective malaria parasites, for example, include over 100 species of Plasmodium and present a diverse array of phenotypes, some …


The Power Of Music To Empower Health And Wellbeing: In Support Of A Music Therapy Discipline At Lehman College, City University Of New York, Felicity A. Howlett Feb 2025

The Power Of Music To Empower Health And Wellbeing: In Support Of A Music Therapy Discipline At Lehman College, City University Of New York, Felicity A. Howlett

Dissertations, Theses, and Capstone Projects

This project seeks to encourage the development of a music therapy curriculum at the City University of New York (CUNY) and specifically at Lehman College. The following paper presents the case and highlights the contents of three data collections that support this goal: 1) The Zotero Digital Music Therapy Reference Collection is a custom-designed index of over 1600 items containing references to published material highlighting significant aspects of the profession. Zotero, a free, open-source reference management software for organizing research, houses the collection and functions as a living library; 2) Music Therapy Degree Programs in New England and the Mid-Atlantic …


Quantified Lives: Data, Bias, And The Cost Of Categorization, Colin F. Geraghty Feb 2025

Quantified Lives: Data, Bias, And The Cost Of Categorization, Colin F. Geraghty

Dissertations, Theses, and Capstone Projects

This project critically examines how statistical methods and data visualization have historically been used to categorize, rank, and control human populations. By exploring the works of key figures like Francis Galton, Karl Pearson, and R.A. Fisher, it traces the evolution of categorization frameworks from their eugenic roots to modern applications in artificial intelligence and global metrics like the World Happiness Report. Through interactive visualizations and historical analysis, the project invites users to question the legitimacy of these frameworks and reflect on their impact on society. At its core, this work emphasizes the need to move beyond rigid classification systems, challenging …


Decades Of Division: Analyzing Hate Crimes In The Usa (1991–2022), Sangeeth Sajan Baby Feb 2025

Decades Of Division: Analyzing Hate Crimes In The Usa (1991–2022), Sangeeth Sajan Baby

Dissertations, Theses, and Capstone Projects

This project comprehensively analyses hate crime data in the United States, leveraging advanced data analysis and visualization techniques to unmask patterns and insights. By utilizing datasets of criminal offenses reported by law enforcement agencies such as the FBI, this study explores the dynamics of hate crimes across racial, religious, gender, and sexual orientation groups. The analysis reveals key findings, including the disproportionate targeting of African Americans and LGBTQ+ individuals, the prevalence of hate crimes in specific locations like residences and educational institutions, and the consistent patterns of attack types and locations across different racial groups. Analysis of crime data over …


Quantifying Educational Impacts Under The Nypd's Stop-And-Frisk Era, Matthew T. Stanton Feb 2025

Quantifying Educational Impacts Under The Nypd's Stop-And-Frisk Era, Matthew T. Stanton

Dissertations, Theses, and Capstone Projects

This project examines the educational and economic impacts of the New York Police Department's "Stop, Question, and Frisk" (SQF) program, implemented predominantly under "Operation Impact" from 2003 to 2022. Using data from the NYPD and the American Community Survey, the study explores correlations between high rates of stop-and-frisk encounters and reduced educational attainment among targeted demographics, primarily Black and Hispanic young men. It contextualizes the socioeconomic consequences of SQF policies, including their effect on lifetime earnings and community trust. The project highlights the limitations of data correlation, advocates for further longitudinal and qualitative studies, and suggests frameworks for mitigating inequities …


Freedom Pedagogy: Black Educators In The Urban North During The Nineteenth And Early Twentieth Centuries, Milagros Seraus-Roache Feb 2025

Freedom Pedagogy: Black Educators In The Urban North During The Nineteenth And Early Twentieth Centuries, Milagros Seraus-Roache

Dissertations, Theses, and Capstone Projects

Black educational history has been told through a predominantly Southern lens. This dissertation highlights the experiences of Black educators in the urban North during the nineteenth and early twentieth centuries. Northern Black educators confronted the challenges of freedom—including the constant need to protect it—using a set of approaches influenced by the various intersecting social movements and intellectual currents of their day. While these educators represented a small minority of African Americans, their contributions were profound, leaving legacies that provide a lens for understanding and improving issues facing urban Black youth and their communities today.

In the absence of a comprehensive …


The Role Of Confined Hydration And Water Reorganization In Molecular Binding, Joe Z. Wu Feb 2025

The Role Of Confined Hydration And Water Reorganization In Molecular Binding, Joe Z. Wu

Dissertations, Theses, and Capstone Projects

An important factor in guiding the development of drug discovery efforts is the comprehensive assessment of a ligand or drug’s ability to bind its receptor. The metric used to measure this interaction strength is by calculating the binding free energy (BFE). To achieve this accurately, we combine two concepts: (1) Grid Inhomogeneous Solvation Theory (GIST) returns the local water thermodynamic and structural contributions to free energy; and the (2) Alchemical Transfer Method (ATM) obtains the absolute (ABFE) and relative binding free energy (RBFE) estimates between ligand pairs. In this work, we employ Alchemical Water-Transfer to tether bridging water(s) during the …


Mad At The System: The Mental Health Act Uk: Power And Control Of Racialized Women, Maithreyi Rajeshkumar Feb 2025

Mad At The System: The Mental Health Act Uk: Power And Control Of Racialized Women, Maithreyi Rajeshkumar

Dissertations, Theses, and Capstone Projects

Whilst experiences of madness are multiple, fluid and multi-dimensional across spiritual and collective dimensions globally, the categorization and regulation of ‘madness’ have direct foundations in European colonial-capitalist-patriarchal frameworks, policies and systems. This work focuses on the institutions and structures of power, turning UK legislation and those who are trying to reform or change it, into objects of study. A particular piece of United Kingdom legislation is the primary case study for this work – the Mental Health Act 1983 which covers the rights, assessment and treatment of people diagnosed with a ‘mental disorder’. Women, who are detained under this Act …


Sex-Specific And Regional Analysis Of Heart Disease Prediction Using Machine Learning Algorithms: Insights From The Uc Irvine Public Heart Disease Datasets (Cleveland And Long Beach), Jonathan Asanjarani Feb 2025

Sex-Specific And Regional Analysis Of Heart Disease Prediction Using Machine Learning Algorithms: Insights From The Uc Irvine Public Heart Disease Datasets (Cleveland And Long Beach), Jonathan Asanjarani

Dissertations, Theses, and Capstone Projects

For this capstone project, I investigated how well machine learning models can predict heart disease, while also studying how the patient’s gender affects these predictions, as well as determining how well the same model performs across different regions. This project utilizes two clinical datasets from the publicly accessible UCI Machine Learning Repository under the collection "Heart Disease." This repository is composed of data from patients across four distinct locations, capturing varying levels of heart disease severity. These datasets are part of a collection of databases, open to the public, and can be used by anyone looking to conduct empirical analysis. …


Destabilizing The Nuyorican: Rivera’S Women And Nuyorican Cinema, Judith R. Escalona Feb 2025

Destabilizing The Nuyorican: Rivera’S Women And Nuyorican Cinema, Judith R. Escalona

Dissertations, Theses, and Capstone Projects

Rivera’s Women, the Capstone, is a TV segment I produced for the CUNY-TV show Latinas that first aired June 27, 2023 (Pride). It grew out of an hour-long interview I conducted with playwright and screenwriter José Rivera as part of my research on Nuyorican Cinema, the films of the Puerto Rican Diaspora.

An unknown part of U.S. independent cinema, these diasporic films destabilize the way independent films continue to be categorized through gender, race, ethnicity, and language. Using the Capstone as a guide, I examine two of Rivera’s recent screen works that situate him within Nuyorican Cinema because of his …


The Role Of Acculturative Stress, Discrimination In Healthcare Settings, And Migration-Related Trauma On Hiv Prevention And Mental Health Among Immigrant Hispanic Sexual Minority Men: An Integrated Model Of Acculturation And Minority Stress, Jonathan Lopez Matos Feb 2025

The Role Of Acculturative Stress, Discrimination In Healthcare Settings, And Migration-Related Trauma On Hiv Prevention And Mental Health Among Immigrant Hispanic Sexual Minority Men: An Integrated Model Of Acculturation And Minority Stress, Jonathan Lopez Matos

Dissertations, Theses, and Capstone Projects

This dissertation expands Minority Stress Theory (MST) by integrating the Fourfold Acculturation Model (FAM) to examine the impact of psycho-sociocultural stressors on health outcomes among immigrant Hispanic sexual minority men (HSMM) in the U.S. The study explored how language proficiency, acculturative stress, discrimination in healthcare, migration-related trauma, and stress-related growth influence HIV prevention behaviors and mental health. Survey data from 194 Spanish-speaking immigrant HSMM revealed that monolingual Spanish speakers experienced significantly higher acculturative stress than bilinguals. Acculturative stress significantly mediated the association between stressors and health outcomes, such as HIV testing and mental health symptoms. Discrimination and trauma were directly …


The Double Victimization Of Black Women At The Crossroads Of Oppression, Carmerina Carrero Feb 2025

The Double Victimization Of Black Women At The Crossroads Of Oppression, Carmerina Carrero

Dissertations, Theses, and Capstone Projects

The purpose of this research study is to amplify the voices of Black women and shed light on the invisibility of Black women’s struggle with police violence and the criminal justice system. The study seeks to expose the different forms of systemic oppressive mechanisms that target Black women, such as mass incarceration and police violence. Through the lenses of intersectionality and critical race theory, the study will explore how racism and sexism contribute to the victimization of Black women via our criminal justice systems and law enforcement. Highlighting the unique experiences of Black women navigating through the criminal justice system, …


The Role Of Secondary And Tertiary Structure In The Cap-Independent Translation Of Fgf-9 And Hif-1-Alpha, Amanda Michelle Whittaker Feb 2025

The Role Of Secondary And Tertiary Structure In The Cap-Independent Translation Of Fgf-9 And Hif-1-Alpha, Amanda Michelle Whittaker

Dissertations, Theses, and Capstone Projects

Under normoxic conditions, eukaryotes initiate translation of RNA through eIF4E recognition of the 5’ cap. However, under cellular stress, eukaryotic translation must be initiated through a 4E-independent, or “cap-independent” mechanism, involving eukaryotic initiation factor 4G (eIF4G) binding directly to the 5’ untranslated regions (5’ UTR) of the RNA. eIF4G binding then recruits the ribosome to the transcript. While this mechanism is useful for translation of apoptotic transcripts and transcripts involved in cell survival, cap-independent translation is also utilized by oncogenic RNA for tumorigenesis. Previous work by our lab and others has categorized this recruitment and initiation mechanism as either internal-ribosome-entry-site …


Let’S Talk About Quality: How Equitable Funding And Program Structure Impact Academic And Social Outcomes In Supplemental Education Programs, Inayah Ansari Feb 2025

Let’S Talk About Quality: How Equitable Funding And Program Structure Impact Academic And Social Outcomes In Supplemental Education Programs, Inayah Ansari

Dissertations, Theses, and Capstone Projects

Although many studies have highlighted how high–quality supplemental education programs (early childhood education and after-school programs) help children and adolescents reach developmental milestones faster, very few studies focus on how programs are structured to create the quality that produces positive outcomes. In this paper, I define quality as equitable funding and program structure and interrogate how this conception of quality determines cognitive and social-emotional benefits, particularly for programs in New York City. Using fiscal data and study reviews, I illuminated the impact of budget cuts on programs and the importance of funding. Using a thematic analysis of six interviews conducted …


The Influence Of Intellectual/Developmental Disabilities (I/Dd) Curriculum Content On Career Interests For Social Work Students, Sabretta G. Alford Feb 2025

The Influence Of Intellectual/Developmental Disabilities (I/Dd) Curriculum Content On Career Interests For Social Work Students, Sabretta G. Alford

Dissertations, Theses, and Capstone Projects

This study examines how curriculum content on Intellectual/Developmental Disabilities (I/DD) impacts the career interests of social work students. With the growing demand for social workers proficient in I/DD services, it is crucial to understand how educational experiences shape career choices. Using a QUANT→Qual mixed-method approach, this quasi-experimental pre/post-test survey combined quantitative data (N 66 [experimental group]; N =103 [control group] and open-ended survey questions (N = 66 [experimental group]; N =103 [control group] from social work students.

The author-constructed survey assessed student attitudes, perceptions, preparedness, ability to identify I/DD, knowledge of I/DD, and willingness to practice with individuals …


Tracing Reverberations: Vietnamese Refugee Mothers' Adaptations To Complex Structural Forces And Intergenerational Engagements, Kim Khanh Nguyen-Nalpas Feb 2025

Tracing Reverberations: Vietnamese Refugee Mothers' Adaptations To Complex Structural Forces And Intergenerational Engagements, Kim Khanh Nguyen-Nalpas

Dissertations, Theses, and Capstone Projects

The main purpose of this study is to learn how refugee mothers adapt to hierarchical systems of oppression with agency and resistance. Global refugee forums and decades of past research on refugees have identified the importance of increasing agency to best support refugees as they resettle. Previous research by the author has demonstrated that refugee mothers model resistance to oppressive systems which has implications for children who witness this resistance. In-depth interviews were conducted with 19 Vietnamese refugee mothers to explore their mothering practices, how they adapted given the socio-political forces shaping their lives, and how these adaptations reverberated through …


Essays On The Impact Of Monetary Policy Shocks, Rubaiyat Tasnim Feb 2025

Essays On The Impact Of Monetary Policy Shocks, Rubaiyat Tasnim

Dissertations, Theses, and Capstone Projects

This dissertation consists of two chapters.

Chapter 1 - Households’ Balance Sheet Adjustment in Response to Monetary Policy Shocks.

Household’s balance sheet and housing decision have played crucial role in understanding the transmission of monetary policy in the last two decades. Monetary policy can affect the broader economy through household finances via the income channel and the wealth channel, and especially of they are debt or liquidity constrained. This chapter studies the unhedged interest rate exposure (URE) following Auclert (2019) for households using micro-level data from the Consumer Expenditure Survey for the years 1994 to 2012. Using the URE, I …


Studies On The Synthesis, Function, And Properties Of Troponoids, John-Charles A. Baucom Feb 2025

Studies On The Synthesis, Function, And Properties Of Troponoids, John-Charles A. Baucom

Dissertations, Theses, and Capstone Projects

Troponoids are a unique class of non-benzenoid aromatic compounds with a wide range of demonstrated applications in pharmaceuticals and molecular sensing. The cycloheptatrienone scaffold possesses a noteworthy degree of tunability as a function of ring oxygenation. This manuscript describes our efforts toward a better understanding of the physical consequences of the scaffold to better utilize the motif. Chapter the first discusses our efforts at elucidating the mechanism of troponoid inhibition of the Hepatitis B virus reverse transcriptase RNAse H enzymatic domain. Using homology modeling in conjunction with traditional in vitro assays we were able to establish the likely mechanism of …


Creating School: Writing And Reading Texts For Children, Carlyn Kolker Feb 2025

Creating School: Writing And Reading Texts For Children, Carlyn Kolker

Dissertations, Theses, and Capstone Projects

Children can come to understand themselves and their lived experience through fiction. Yet writing, reading, and interpreting fiction for children are all projects that challenge society’s commonly-understood beliefs about childhood, literature, and even the category of children’s literature itself.

This capstone project uses a cross-disciplinary approach to examine the notion of what it means to write fictional texts directed at children, and in particular, how fiction presents the deeply-contested American institution of school and the school environment. This project consists of two parts. The first is a critical consideration of how contemporary literary texts directed at children portray conditions of …


The Material Folklore Of Occult Zines, Jacqueline G. Coffey Feb 2025

The Material Folklore Of Occult Zines, Jacqueline G. Coffey

Dissertations, Theses, and Capstone Projects

This capstone is a paper on and catalog of contemporary occult zines. Through the collecting, arranging, and analyzing of about one hundred zines, I stipulate that these zines draw from the rich and rebellious histories of both the occult and zines. With the dominating influence of multi-industry corporations on our lives, these often independently produced and handmade texts are evidence of the mystical and mysterious forces with which we still grapple. Not only do zines showcase the breadth of spiritual possibility, they can also be used to integrate new metaphysical awareness into mundane reality.

The catalog is also intended to …


Characterizing The Nutrition-Gut Microbiome-Host Physiology Axis To Examine Flexibility In A Fruit-Specialist Primate, Nina Beeby Feb 2025

Characterizing The Nutrition-Gut Microbiome-Host Physiology Axis To Examine Flexibility In A Fruit-Specialist Primate, Nina Beeby

Dissertations, Theses, and Capstone Projects

Nutrition and, increasingly, microbiota are recognized in shaping all aspects of animal behavioral ecology and physiology. Since diet and nutrition shape not only animal physiology but also gut microbiota, and these microbiota serve as suppliers of and competitors to host nutrition, this raises questions of how these complex nutritional and microbial environments synergistically affect animal physiology. Examining this nutrition-gut microbiome-host physiology axis has immense potential to unveil how these intricate relationships contribute to animals’ responses to environmental change at multiple scales. Most of what we know about primate responses to environmental change is based upon studies examining one or few …


Tracing The Sources Of Nitrogen In Submarine Groundwater Discharge And Primary Producers In The Great South Bay Estuary, Nia H. Rene Feb 2025

Tracing The Sources Of Nitrogen In Submarine Groundwater Discharge And Primary Producers In The Great South Bay Estuary, Nia H. Rene

Dissertations, Theses, and Capstone Projects

The primary aim of this research was to elucidate the impact of submarine groundwater discharge (SGD) and septic effluent on coastal primary producers in the Great South Bay (GSB). The study focused on three main objectives: assessing the impact of precipitation patterns on SGD, tracing nitrogen sources into the GSB, and determining the impact of these nitrogen sources on coastal primary producers. The research revealed that current precipitation patterns significantly influence SGD across different seasons, highlighting the seasonal variability in groundwater discharge and its implications for nutrient loading in coastal waters. A suite of tracers was employed to identify and …


The U.S. Grand Strategy Toward The Pacific Islands, Angela Vasovic Feb 2025

The U.S. Grand Strategy Toward The Pacific Islands, Angela Vasovic

Dissertations, Theses, and Capstone Projects

The United States has recently placed its relations with the Pacific Islands, fourteen small states far out in the Pacific Ocean, on its high-priority diplomatic agenda. Although it has been interacting with the islands since the 1800s and had heavily relied on their cooperation during World War II, the importance of the islands waned in the eyes of the United States in the late twentieth and the beginning of the twenty first century as the country turned its attention to other regions of the world. However, in recent years, the U.S. has recognized the need to strengthen relations with the …


Synchronizing Work And Teaching Practices With The Spatial Dna Of Distributed Work And Learning, Manju Aishwarya Adikesavan Feb 2025

Synchronizing Work And Teaching Practices With The Spatial Dna Of Distributed Work And Learning, Manju Aishwarya Adikesavan

Dissertations, Theses, and Capstone Projects

Phygitality, the seamless and synergistic integration of physical and digital realms, is an indispensable and irrevocable part of contemporary office-based work. Phygitality facilitates spatially and temporally distributed or multi-local working where employees work from diverse locations such as their home, office, and third places at any time of day or night. It also makes nonterritorial working at temporary workspaces accessed on a session-by-session basis possible.

This dissertation examines how phygital, multi-local, and nonterritorial working reshape individual and group work behaviors, organizational spatial practices, work-centric settings, non-work-centric settings, neighborhoods, cities, and regions. The Spatial DNA of Distributed Work encapsulates a conceptual …


The Perspectives Of Play Advocates On Children’S Unstructured Play In Turkey, Bengi Sullu Feb 2025

The Perspectives Of Play Advocates On Children’S Unstructured Play In Turkey, Bengi Sullu

Dissertations, Theses, and Capstone Projects

The Convention on the Rights of the Child has established children’s rights to non- discrimination, development, participation and the observance of their best interests. With this recognition, there has been a growing global interest in acknowledging play as a right. Yet unstructured play, in which children can choose when, where and how to play, with control over their play, has not received the same attention, support and investment as organized, structured play (UNCRC General Comment 17, 2013). The way adults perceive and support play shapes the play opportunities that are available to children (Bianquin, 2018; Göl-Güven, 2017). Additionally, institutions and …


A Meta-Analysis Of Intimate Partner Violence Treatment Programs: The Role Of Risk-Need-Responsivity In Treatment Effectiveness, Irina Fanarraga Feb 2025

A Meta-Analysis Of Intimate Partner Violence Treatment Programs: The Role Of Risk-Need-Responsivity In Treatment Effectiveness, Irina Fanarraga

Dissertations, Theses, and Capstone Projects

Nationally, it is estimated that over 17 million people experience victimization by an intimate partner every year. Additionally, individuals who perpetuate intimate partner violence (IPV) often have high rates of re-offending, potentially as high as 60%. IPV Treatment Programs (ITPs) are interventions designed to reduce recidivism among intimate partner violent individuals by changing their thinking and behaviors, ultimately leading to increased victim safety. Although there is significant evidence to suggest that correctional treatment programs can reduce re-offending, the literature on ITPs is less clear about their effectiveness in reducing recidivism among participants. Furthermore, while other correctional interventions have taken more …


Vertex-Based Analysis Of Cerebral Blood Flow And Fractional Amplitude Of Low-Frequency Fluctuations (Cbf-Falff) Coupling In Moderate-To-Severe Traumatic Brain Injury During The First Year Post-Injury, Vaidehi Hemkumar Patel Feb 2025

Vertex-Based Analysis Of Cerebral Blood Flow And Fractional Amplitude Of Low-Frequency Fluctuations (Cbf-Falff) Coupling In Moderate-To-Severe Traumatic Brain Injury During The First Year Post-Injury, Vaidehi Hemkumar Patel

Dissertations, Theses, and Capstone Projects

Traumatic brain injury (TBI) is known to involve damage in the neurovascular unit. TBI may disrupt the brain’s neurovascular coupling–the relationship between cerebral blood flow and neural activity–that can lead to cognitive and functional impairments. This study attempted to non-invasively investigate neurovascular coupling in patients with moderate to severe TBI (msTBI) during the first year post-injury using a combined metric of cerebral blood flow (CBF) and fractional amplitude of low-frequency fluctuations (fALFF), a proxy for spontaneous neural activity. Using arterial spin labeling (ASL) and functional MRI sequences, CBF and fALFF were measured in 29 msTBI patients 3-, 6- and 12-months …