Digital Commons Network^™

Hippocampal Subfield Volumetry From Structural Isotropic 1 Mm3 Mri Scans: A Note Of Caution, Laura E.M. Wisse, Gaël Chételat, Ana M. Daugherty, Robin De Flores, Renaud La Joie, Susanne G. Mueller, Craig E.L. Stark, Lei Wang, Paul A. Yushkevich, David Berron, Naftali Raz, Arnold Bakker, Rosanna K. Olsen, Valerie A. Carr

Faculty Research, Scholarly, and Creative Activity

Spurred by availability of automatic segmentation software, in vivo MRI investigations of human hippocampal subfield volumes have proliferated in the recent years. However, a majority of these studies apply automatic segmentation to MRI scans with approximately 1 × 1 × 1 mm3 resolution, a resolution at which the internal structure of the hippocampus can rarely be visualized. Many of these studies have reported contradictory and often neurobiologically surprising results pertaining to the involvement of hippocampal subfields in normal brain function, aging, and disease. In this commentary, we first outline our concerns regarding the utility and validity of subfield segmentation on …

"I Wish I Had Known"—Understanding Barriers To Accessing Aging-Related Resources, Sue Schneider, Allyson Brothers

Journal of Extension

There is a growing imperative to ensure that aging-related resources and information are accessible to older adults and caregivers as the population ages. Extension can play an important role in associated education and outreach. We report on the results of a community assessment conducted in Larimer County, Colorado, that addressed barriers to information access. The results of our assessment demonstrated that many people were not finding the right entry point to access the services they needed. These findings inform strategies being applied in Senior Access Points of Larimer County, a program that encompasses a coordinated, county-wide outreach campaign.

Prevalence Of Functional Limitation In Covid-19 Recovered Patients Using The Post Covid-19 Functional Status Scale, Pankaj Pant, Aishana Joshi, Babin Basnet, Bibek Man Shrestha, Navindra Raj Bista, Niraj Bam, Santa Kumar Das

Faculty, Staff and Student Publications

INTRODUCTION: COVID-19 is an emerging global health pandemic causing tremendous morbidity and mortality worldwide. Chronic symptoms progressing to poor functional status have been reported in a substantial proportion of COVID-19 patients worldwide. This study aimed to determine the prevalence of functional limitation in COVID-19 recovered patients using the post-COVID-19 functional status scale.

METHODS: A descriptive cross-sectional study was conducted at Tribhuvan University Teaching Hospital. COVID-19 recovered patients with reverse transcription-polymerase chain reaction negative status were included and assessed using the post-COVID-19 functional status scale. Data entry and analysis was done in Statistical Package for the Social Sciences version 20.0. Descriptive …

Development Of The Asia Pacific Consortium On Osteoporosis (Apco) Framework: Clinical Standards Of Care For The Screening, Diagnosis, And Management Of Osteoporosis In The Asia-Pacific Region, M Chandran, P J. Mitchell, T Amphansap, S K. Bhadada, M Chadha, D-C Chan, Y-S Chung, P Ebeling, N Gilchrist, Aysha Habib Khan

Department of Pathology and Laboratory Medicine

Guidelines for doctors managing osteoporosis in the Asia-Pacific region vary widely. We compared 18 guidelines for similarities and differences in five key areas. We then used a structured consensus process to develop clinical standards of care for the diagnosis and management of osteoporosis and for improving the quality of care.
Purpose: Minimum clinical standards for assessment and management of osteoporosis are needed in the Asia-Pacific (AP) region to inform clinical practice guidelines (CPGs) and to improve osteoporosis care. We present the framework of these clinical standards and describe its development.
Methods: We conducted a structured comparative analysis of existing CPGs …

2021-January-26-College Of Nursing Among Best Online Programs, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY (Jan. 26, 2021) –  East Tennessee State University’s College of Nursing is ranked nationally among U.S. News & World Report’s 2021 Best Online Programs.

ETSU ranked No. 16 among the “Best Online Master’s in Nursing Administration Programs” and No. 75 among the “Best Online Master’s in Nursing” programs.

“These rankings are a testament to our dedicated, well-prepared faculty and their expertise in their teaching areas,” said Dr. Myra Carew, associate dean for the ETSU College of Nursing. “Not only did we move up in our ranking this year for our Master of Science in Nursing (MSN), but for …

Exercise Shifts Hypothetical Food Choices Toward Greater Amounts And More Immediate Consumption, Karsten Koehler, Safiya E. Beckford, Elise Thayer, Alexandra R. Martin, Julie B. Boron, Jeffrey R. Stevens

Department of Nutrition and Health Sciences: Faculty Publications

Although exercise modulates appetite regulation and food intake, it remains poorly understood how exercise impacts decision-making about food. The purpose of the present study was to assess the impact of an acute exercise bout on hypothetical choices related to the amount and timing of food intake. Forty-one healthy participants (22.0 ± 2.6 years; 23.7 ± 2.5 kg/m² , 56% female) completed 45 min of aerobic exercise and a resting control condition in randomized order. Food amount preferences and intertemporal food preferences (preference for immediate vs. delayed consumption) were assessed using electronic questionnaires with visual food cues. Compared to rest, …

Perceptions Of Two Older Adults Regarding The Factors And Barriers That Influence Their Oral Health Care: A Case Study, Dinorah Munira Hernández-Santos Msg., Irma Fabiola Díaz-García Phd.

The Qualitative Report

This paper presents the results of a case study about the perceptions of oral health care, factors that influenced current oral health, and barriers to dental attention of two older adults; the study was conducted by researchers from a hospital-school of dentistry at a public university in Mexico. Two adults aged 64 and 70 years participated in this study. First, the oral health status was clinically evaluated using the Decayed/Missing/Filled/Teeth (DMFT) Index. A semi-structured interview was then conducted to learn about the perceptions of oral health care. Thematic content analysis was used to explore the data obtained using the ATLAS.ti …

Early Stages Of Alzheimer's Disease: Evolving The Care Team For Optimal Patient Management., James E Galvin, Paul Aisen, Jessica B Langbaum, Eric Rodriguez, Marwan Sabbagh, Richard G. Stefanacci Do,Mgh,Mba,Agsf,Cmd, Robert A Stern, Elizabeth A Vassey, Arno De Wilde, Neva West, Ivana Rubino

College of Population Health Faculty Papers

Alzheimer's disease (AD) is a progressive, neurodegenerative disease that creates complex challenges and a significant burden for patients and caregivers. Although underlying pathological changes due to AD may be detected in research studies decades prior to symptom onset, many patients in the early stages of AD remain undiagnosed in clinical practice. Increasing evidence points to the importance of an early and accurate AD diagnosis to optimize outcomes for patients and their families, yet many barriers remain along the diagnostic journey. Through a series of international working group meetings, a diverse group of experts contributed their perspectives to create a blueprint …

Age And Sex Differences In Load-Induced Tibial Cortical Bone Surface Strain Maps, Alessandra Carriero, Behzad Javaheri, Neda Bassir Kazeruni, Andrew A. Pitsillides, Sandra J. Shefelbine

Publications and Research

Bone adapts its architecture to the applied load; however, it is still unclear how bone mechano-adaptation is coordinated and why potential for adaptation adjusts during the life course. Previous animal models have suggested strain as the mechanical stimulus for bone adaptation, but yet it is unknown how mouse cortical bone load-related strains vary with age and sex. In this study, full-field strain maps (at 1 N increments up to 12 N) on the bone surface were measured in young, adult, and old (aged 10, 22 weeks, and 20 months, respectively), male and female C57BL/6J mice with load applied using a …

Intergenerative Transdisciplinarity In “Glocal” Learning And Collaboration, Peter J. Whitehouse

Faculty Scholarship

In this report, authors from North America, Africa, Europe, and Asia share commonalities and differences in the lessons we are learning from COVID-19, especially about scholarship and collaboration. We represent different ages and disciplines hence our focus on intergenerational perspectives and transdisciplinary considerations. Our work is intergenerative{that is going "between to go beyond" by connecting creative sources of culture and focusing on the emergent, that is responding to changes in the context in which we work. And importantly in our view, we will point beyond whatever the next phase of COVID or even the next pandemic brings to a more …

The Association Of Circulating Amylin With Β-Amyloid In Familial Alzheimer's Disease, Han Gia Ly, Nirmal Verma, Savita Sharma, Deepak Kotiya, Sanda Despa, Erin L. Abner, Peter T. Nelson, Gregory A. Jicha, Donna M. Wilcock, Larry B. Goldstein, Rita Guerreiro, José Brás, Angela J. Hanson, Suzanne Craft, Andrew J. Murray, Geert Jan Biessels, Claire Troakes, Henrik Zetterberg, John Hardy, Tammaryn Lashley, Alzheimer’S Disease Exome Sequencing Group, Florin Despa

Pharmacology and Nutritional Sciences Faculty Publications

Introduction

This study assessed the hypothesis that circulating human amylin (amyloid‐forming) cross‐seeds with amyloid beta (Aβ) in early Alzheimer's disease (AD).

Methods

Evidence of amylin‐AD pathology interaction was tested in brains of 31 familial AD mutation carriers and 20 cognitively unaffected individuals, in cerebrospinal fluid (CSF) (98 diseased and 117 control samples) and in genetic databases. For functional testing, we genetically manipulated amylin secretion in APP/PS1 and non‐APP/PS1 rats.

Results

Amylin‐Aβ cross‐seeding was identified in AD brains. High CSF amylin levels were associated with decreased CSF Aβ42 concentrations. AD risk and amylin gene are not correlated. Suppressed amylin secretion protected …

Inter-Rater Reliability Of Goal Attainment Scaling With Children With Sensory Processing Disorder, Teresa A. May-Benson, Sarah A. Schoen, Alison Teasdale, Jane Koomar

The Open Journal of Occupational Therapy

Background: Goal Attainment Scaling (GAS) is advocated as a meaningful outcome measure for parents and clinicians using an Ayres Sensory Integration^® Intervention (ASI) approach. Although used in several treatment effectiveness studies, reliability of therapist goal writing and scoring has not been established in this area.

Method: Ten occupational therapists and 40 parents of children receiving ASI participated across two clinical sites. The interview therapists and inter-rater therapists wrote GAS goals based on the same goal-setting interviews conducted with parents. Follow-up parent interviews were conducted post-ASI intervention, and the GAS goals were rated by both the interview therapists …

Evaluation Of Anticipatory Postural Adjustment Before Quantified Weight Shifting—System Development And Reliability Test, Jiunn-Woei Liaw, Rou-Shayn Chen, Vincent Chiun-Fan Chen, Yan-Ru Wang, Hsiao-Lung Chan, Ya-Ju Chang

Engineering Science Faculty Publications

Anticipatory postural adjustment (APA) existed before a self-induced perturbation is an important motor control skill for balance and gait initiation, but cannot be easily monitored. During proactive balance test, a self-initiated weight shifting is produced. This might be an optimal paradigm for APA measurement. The purpose of this study was to investigate if APAs existed in the proactive balance test which consists of quantifiable weight shifting. The feature and reliability of the APAs were also evaluated. We firstly built a proactive balance test program on the commercially available Wii balance board. The program could generate adjustable target direction and distance …

Functional Constipation Induces Bladder Overactivity Associated With Upregulations Of Htr2 And Trpv2 Pathways., Nao Iguchi, Alonso Carrasco, Alison X. Xie, Ricardo H. Pineda, Anna P. Malykhina, Duncan T. Wilcox

Manuscripts, Articles, Book Chapters and Other Papers

Bladder and bowel dysfunction (BBD) is a common yet underdiagnosed paediatric entity that describes lower urinary tract symptoms (LUTS) accompanied by abnormal bowel patterns manifested as constipation and/or encopresis. LUTS usually manifest as urgency, urinary frequency, incontinence, and urinary tract infections (UTI). Despite increasing recognition of BBD as a risk factor for long-term urinary tract problems including recurrent UTI, vesicoureteral reflux, and renal scarring, the mechanisms underlying BBD have been unclear, and treatment remains empirical. We investigated how constipation affects the lower urinary tract function using a juvenile murine model of functional constipation. Following four days of functional constipation, animals …

Connecting Policy To Licensed Assisted Living Communities, Introducing Health Services Regulatory Analysis., Lindsey Smith, Paula Carder, Taylor Bucy, Jaclyn Winfree, Joan F. Brazier, Brian Kaskie, Kali S. Thomas

Institute on Aging Publications

To document dementia-relevant state assisted living regulations and their changes over time as they pertain to licensed care settings.

Self-Rated Health Status, Functional Difficulties In Health Domains And Non-Communicable Diseases In Oman: Evidence From The World Health Survey In Oman, Mamunur Rashid, M. Mazharul Islam, Ahmed Y. Al Hadhrami

Mathematics Faculty Publications

This paper examined the pattern of self-rated Health (SRH) status, functional difficulties in health domains and non-communicable diseases among the Omani adult people. The paper also evaluated the association of SRH with the health functional difficulties and the chronic diseases. The data for the study obtained from the 2008 Oman World Health survey, involving a nationally representative sample of 3,770 Omani adult respondents of age 18 and above. Both descriptive and inferential statistical techniques, such as frequency distribution, bivariate analysis with chi-square test, factor analysis, multiple linear regression and logistic regression analysis were used for data analysis. The study revealed …

Sex Differences And Psychological Stress: Responses To The Covid-19 Pandemic In China, Shiyan Yan, Rui Xu, Terry D. Stratton, Voyko Kavcic, Dan Luo, Fengsu Hou, Fengying Bi, Rong Jiao, Kangxing Song, Yang Jiang

Behavioral Science Faculty Publications

BACKGROUND: About 83,000 COVID-19 patients were confirmed in China up to May 2020. Amid the well-documented threats to physical health, the effects of this public health crisis - and the varied efforts to contain its spread - have altered individuals' "normal" daily functioning. These impacts on social, psychological, and emotional well-being remain relatively unexplored - in particular, the ways in which Chinese men and women experience and respond to potential behavioral stressors. Our study investigated sex differences in psychological stress, emotional reactions, and behavioral responses to COVID-19 and related threats among Chinese residents.

METHODS: In late February (2020), an anonymous …

Assisted Living Communities That Accept Medicaid Are Not Subject To Federal Oversight, Lindsey Smith, Sarah Dys, Paula Carder

Institute on Aging Publications

We commend Mauldin et al. (2020) for their recent article titled “Supports and gaps in federal policy for addressing racial and ethnic disparities among long-term care facility residents,” which addresses opportunities to mitigate racial and ethnic disparities in long-term care (LTC) through federal policies. However, we would like to clarify a statement regarding federal oversight of assisted living (AL) communities made by the authors.

Are Nurses Joining The Ride? Equine-Assisted Activities And Therapies Review, Khalid Bandar Almasloukh, Pamela Stewart Fahs

People and Animals: The International Journal of Research and Practice

Background: Equine-assisted activities and therapies (EAAT) is a rapidly growing practice that is described as therapeutic and entertaining. Complementary therapies such as EAAT are gaining acceptance as the health care needs of the population are changing.

Method: This systematic review draws from four databases. The final review included 52 articles.

Purpose: To explain what is known about EAAT and identify literature gaps. Nursing and rural perspectives are included in the analysis and recommendations.

Findings: There are more than eight types of EAAT and different organizations around the world are providing certification for EAAT. Rural communities and organizations may benefit from …

Current Trauma Problems In Gerontological Patients After Lower Limb Injury (Literature Review), M.Yu. Karimov, N.R. Kobilov, N.U. Ismailov, Sh.S. Muslimov

Central Asian Journal of Medicine

Older adults sustain frequent orthopedic injuries that may result in devastating consequences to their overall health, function, mobility, and independence, and even in death. Objective: Our aim in this article is to provide the readers with a review of current trauma problems in gerontological patients after lower limb injury.

Comparison Of Balance Variables Across Active And Retired Athletes And Age Matched Controls, Caitriona Lee, Neil Fleming, Bernard Donne

International Journal of Exercise Science

International Journal of Exercise Science 14(3): 76-92, 2021. Postural control is a major falls risk factor, therefore identifying protective mechanisms is essential. Physical activity enhances postural stability but effect duration has been minimally researched. The current study investigated if prolonged early life training exposure protected neuromuscular balance processes later in life. Static and dynamic balance variables were assessed in 77 healthy adults. Two age ranges (18 - 35yr, young; > 50yr, retired) were divided into weight bearing athlete and control groups; young athlete (YA), young control (YC), retired athlete (RA) and retired control (RC). Static balance was quantified using force platform …

A Population Dynamics Tipping Point For Aging As A Cause Of Adult Death, Andrea Scharf

Biological Sciences Faculty Research & Creative Works

Populations are a fundamental level of biological organization that poses major challenges for analysis. Individual traits that influence development, diapause, reproduction, aging, and lifespan interact in complex ways to determine birth and death. Birth and death drive population dynamics and determine whether a population survives or is doomed for extinction. However, we lack a deep understanding of the relationships between individual traits and population dynamics, a major challenge in the emerging field of ecology-development (eco-devo). Here we establish a laboratory ecosystem using the model organism C. elegans and a computational simulation that realistically models the laboratory ecosystem. We used these …

Neuroprotective Effects Of Asparagus Officinalis Stem Extract In Transgenic Mice Overexpressing Amyloid Precursor Protein, Zhanglong Peng, Supinder Bedi, Vivek Mann, Alamelu Sundaresan, Kohei Homma, Gregory Gaskey, Minoru Kowada, Shahid Umar, Anil D. Kulkarni, Holger K. Eltzschig, Marie Francoise Doursout

Faculty Publications

To mimic Alzheimer's disease, transgenic mice overexpressing the amyloid precursor protein (APP) were used in this study. We hypothesize that the neuroprotective effects of ETAS®50, a standardized extract of Asparagus officinalis stem produced by Amino Up Co., Ltd. (Sapporo, Japan), are linked to the inhibition of the apoptosis cascade through an enhancement of the stress-response proteins: heat shock proteins (HSPs). APP-overexpressing mice (double-transgenic APP and PS1 mouse strains with a 129s6 background), ages 6-8 weeks old, and weighing 20-24 grams were successfully bred in our laboratory. The animals were divided into 5 groups. APP-overexpressing mice and wild-type (WT) mice were …

Annual Report 2019-2020: Student Life & Development, Denise Mcdowell, Gale Lanning, Kendra Weber, Alex Kromminga, Kateri Johnson, Karen Johnson, Johnathan Locust Jr., Connie M. Kamara, Kate Noelke, George Micalone, Tracy Rahim, Lindsay Marosi-Kramer, Paul Stern, Mari Livingston, Tania Schmidt, Jami Koivisto, Ron Strege

Annual Reports

Student Life and Development (SLD) professionals at Winona State University (WSU) deliver programs, services, and activities that support students' academic achievement, social development, and well-being in the timely pursuit of their educational goals. The 2019-2020 SLD Annual Report provides information from the following departments: Admissions, Community Engagement, Conduct & Citizenship, Counseling and Wellness Services, Dean of Students, Equity & Inclusion Excellence, Health & Wellness, Housing & Residence Life, Integrative Wellness, Student Union & Activities, TRIO Student Support Services, the Warrior Hub, and the Warrior Success Center.

Reducing Hospital Readmissions Using The Self Care Deficit Theory, Katherine Decillis Taylor

Master of Science in Nursing Theses and Projects

This project aims to reduce inpatient hospital readmission occurrences within 30 days of an initial inpatient hospitalization. Patients at high risk for readmission may have deficits in their ability to meet self-care needs after discharge. Orem’s Self-Care Deficit Nursing Theory provided the theoretical framework for the project. The education provided by this project can teach nurses to identify patients who may be at high risk for readmission. Once identified, nurses can advocate for the patient’s needs.

Balance And Bloom: Encouraging Self-Regulation And Resilience Through Yoga And Mindfulness, Kayla Previti

OT Student Capstones

The experiences an individual has throughout their childhood sets the foundation for their overall life trajectory. Adverse childhood experiences (ACEs) leave a lifelong impact on a person's mental, emotional, spiritual, and physical health. It is estimated that the impact of ACES on an individual leads to an economic burden of $830,928 in terms of such services as law enforcement, child welfare, medical treatment, hospitalization, and loss of productivity and wages (Fang, Brown, Florence, & Mercy, 2012; Peterson, Florence, & Klevens, 2018). Occupational therapists and other health professionals have the ability to develop programs that fill the gaps in preventing and …

Development Of Clinical Practice Guidelines For Chemotherapy-Induced Peripheral Neuropathy Rehabilitation, Rikki Silver

OT Student Capstones

In the past four decades, there have been significant improvements in early cancer detection and efficacy of cancer treatments, resulting in a growing number of cancer survivors. People diagnosed with cancer are now living longer than ever before; while lifespan after cancer is increasing, cancer survivors are experiencing health and functional challenges due to the persistent effects of curative therapy (Rowland et al., 2018). One of these effects includes chemotherapy-induced peripheral neuropathy (CIPN). Approximately 70% of patients receiving neurotoxic chemotherapy experience CIPN, an uncomfortable and sometimes painful sensation in the hands and feet (Seretny et al., 2014). The likelihood of …

Course Catalog 2021-2022, Csusb

CSUSB Course Catalog

No abstract provided.

An Analysis Of Education As A Moderator Of The Relationship Of Discrimination To Depression, Jeavonna M. Coble

Theses and Dissertations

Racism has been observed as a highly prevalent psychosocial stressor across minorities, and consistently associated with depression across racial/ethnic groups. However, existing evidence is unclear on effective buffers of discrimination to depression. Researchers have hypothesized that education may mitigate discrimination’s effects on negative mental health outcomes. Evidence evaluating education as a buffer on the relations of discrimination to depression is limited. The analysis is further complicated as the evidence linking education level to discrimination exposure is also mixed. Although some studies indicate lower education levels are associated with greater perceived racism, many studies indicate an association of higher education with …

Prevention Of Falls In Adults Older Than 60 Years Through Therapeutic Riding: A Critically Appraised Topic, Isabella Johannes, Dominique Menard, Alicia Young

Critically Appraised Topics

This critically appraised topic paper will address the focus question relating to the intervention of therapeutic riding. A critically appraised topic (CAT) is an overview of scientific literature about an intervention or practical issue and how it relates to practice (Barends et al., 2017). The use of the Ecological Human Performance (EHP) model is to guide this CAT research with a theoretical basis. EHP was chosen for its emphasis on the person, environment, and tasks. The person is described in EHP as including their experiences, sensorimotor, cognition, and psychosocial abilities (Dunn et al., 1994). The use of EHP provides a …