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The Effects Of Astrocytic Derived Insulin-Like Growth Factor (Igf-1) On Cognition And Astrocytes, Destiny Wilson

Honors Theses

Insulin-like growth factor 1 (IGF-1) is a neuroendocrine signaling hormone that plays a vital role in growth and development, as well as learning and memory. Inhibition of this hormone results in cognitive impairments like those seen with age-related decline. While a majority of research has focused on the role of IGF-1 on neurons, the role of astrocytes still needs to be explored. Our research investigates how astrocytes and cognition are affected as a result of direct regulation of localized IGF-1 production in early development and after puberty. Preliminary studies in our laboratory established a connection between IGF-1 and glial fibrillary …

Investigating The Neuroprotective Effects Of Cannabinoids And Insulin-Like Growth Factors On Glia With Induced Inflammation, Caleb Bloodworth

Honors Theses

Chronic inflammation is a driver of numerous neurodegenerative diseases that reduce quality of life for affected individuals. Non-psychoactive cannabinoids have begun to gain more interest in the world of anti-inflammatory medicine for chronically ill patients. Along with these cannabinoids, insulin-like growth factor-1 has been examined for its association with downregulation of inflammation. Our research aimed to investigate how neuroglia are affected by treatment with cannabinoids or IGF-1 in the face of inflammation from HIV-1 protein, Tat, or lipopolysaccharide (LPS). Preliminary studies in our laboratory showed that neither cannabinoids or IGF-1 treatment altered astrocyte morphology or overall astrocyte viability under baseline …

Impacts Of Diabetes Stigma On Acute Healthcare Engagement Among Adults With Type 2 Diabetes, Kate Camillo

Honors Theses

Introduction: Individuals frequently experience public and self-stigma stemming from type 2 diabetes. Prior studies have linked stigma with higher levels of poorer diabetes outcomes such as greater disease-related distress and worse glycemic control. However, few if any studies have examined the association between diabetes-related stigma and healthcare utilization. This gap in the literature is critically important given the importance of proactive disease management and preventive care as well the high costs of acute service use in this population. Therefore, the purpose of the present study was to examine the relationship between type 2 diabetes stigma, patient activation, and acute medical …

An Exploratory Look Into The Effects Of Mississippi's Population Decline On Rural Dental Care, Allen Bailey Saffold

Honors Theses

Literature reviews and interviews with dentists working in rural Mississippi counties examined the effects of population decline on rural dental care in Mississippi. With the state’s continual population decline, loss of industry follows a loss of people. Through a cascade of effects, this can further reduce underserved areas’ access to dental care. In order to address the issue of rural Mississippi continuing to be underserved, policies need to be implemented that will make rural practice at least enticing if not desirable.

Finding Resilience Through Research: Completing A Ph.D. While Parenting An Intellectually Disabled Adult “Child”, Lorraine M. Hutton

The Qualitative Report

Unlike the progression of most traditional-aged, college or university students, my non-traditional, academic trajectory as a parent-caregiver to an intellectually disabled (ID) adult has been fraught with barriers, disruption, and discouragement. Motivation to complete my doctorate rests on a commitment to disability issues, caregiver activism, and intellectual capacity-building of my self. Guided by the “evocative” autoethnographic methodology of Bochner and Ellis (2016), this “insider’s” narrative retrospective autoethnography will attempt to shed light on and evoke an understanding of a doctoral student caregiver’s context and experience in the academy. It encompasses embodiment, a geographically constrained sense of place, marginalization, and neoliberal …

Ageism, Eldercare, And Healthcare: An Examination Of Growing Old In Costa Rica, Akshaya Vijayasankar

Honors Theses

The world’s aging population and the Covid-19 pandemic have revealed the high level of ageism against older adults around the globe, which has resulted in an overall decreased quality of life for elders. Societies are now faced with the challenge of creating a suitable and equitable model of care to support their aging population. Despite the recent publication of the World Health Organization's Global Report on Ageism, there is still a large gap in the literature regarding ageism. This paper addresses the issues of institutional ageism in the eldercare and healthcare sector. I argue that Costa Rica serves as a …

A Look Towards The Future Of Eldercare: Lessons Learned From Social Care Models In Japan, Caroline M. Steil

Honors Theses

The rapidly accelerating trend of population aging is redefining the state of eldercare globally, as every country is currently or will soon face a gap in the excess demand for care versus the scarce supply of caregivers, both formal and informal. Specifically, there is a decrease in the number of elders seeking care through a family member as well as less caregivers in institutions to provide care for elders. Japan is at the vanguard of this caregiving gap, and thus provides key lessons, particularly from two innovative models of eldercare: Ibasho, a grass-roots, non-profit organization, and Japan's Long-Term Care Insurance …

Planning For An Aging Population: The Sustainability Conundrum, Sandi Rosenbloom

Journal of Comparative Urban Law and Policy

By 2030 more than one in four Americans will be 65 years of age or older. What role do city planning academics and practitioners play in planning for the inevitable and increasing aging of society? I examined original research and reviewed articles published in three major planning journals, reviewed the websites of ten Planning Accreditation Board (PAB) accredited planning programs, and evaluated the websites of the American Planning Association’s divisions and special interest groups to determine how each demonstrated or portrayed the value and importance of aging issues in planning scholarship, pedagogy, and practice. I found that these key pillars …

2022 Spring Order Of Exercises Commencement: Winona State University, Winona State University

WSU Commencement Programs

This is the Winona State University Spring 2022 Order of Exercises booklet published for the commencement ceremony on Friday, May 6, 2022.

Implementation And Evaluation Of An End-Of-Life Standardized Participant Simulation Into An Adult/Gerontology Acute Care Nurse Practitioner Program, Shannon Daly

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

Palliative care interventions are in high demand due to patients living longer with chronic, life-limiting conditions. Nursing professionals are instrumental in the care of patients across their lifespan, and it is imperative that they receive end-of-life care training in their respective curriculums. The aims of this project were to 1) implement end-of-life content into an AGACNP program using the ELNEC curriculum and 2) to determine if the simulated environment affects the AGACNP students’ self-confidence and anxiety levels when making clinical decisions for end-of-life patients. As a result of the standardized participant (SP) end-of-life simulation, AGACNP students experienced an increase in …

2022 Spring Commencement Program: Winona State University, Winona State University

WSU Commencement Programs

This is the Winona State University Spring 2022 commencement program. Commencement was on Friday, May 6, 2022.

Factors Associated With Advance Care Planning Engagement In Healthy Young Adults, Pablo J. Vasquez

Dissertations and Theses (Open Access)

Background: Advance care planning (ACP) is a process that supports individuals at any stage of health in understanding and sharing their personal values and goals pertaining current or future medical needs with their families and healthcare providers. Although ACP is applicable to adults of any age and any stage of the health continuum, it is widely associated with older or terminally ill populations, and the need for end-of-life (EOL) planning in healthy young adults is generally found unnecessary. The National Institutes of Health supports the expansion of ACP research in understudied populations. Investigating ACP in healthy young adults support such …

Conducting A Root Cause Analysis To Improve Intake Processes And Record Review In Home Health, Christina Guerrero

Doctor of Nursing Practice Projects

Minimization of adverse events, reduction of inpatient admissions, and prevention of polypharmacy within home health are of importance due to the increasing number of Medicare beneficiaries. In 2019, CMS reported 5,266,931 patients were served by home health agencies, accounting for 7,439,849 episodes of care. It is projected that the number of beneficiaries will rise from 54 million to more than 80 million by the year 2030. Medical errors are now the third-leading cause of death in the United States, surpassing diabetes, Alzheimer’s, and stroke. The Agency for Healthcare Research and Quality identifies a lack of institutional intake processes as the …

Telemedicine Across Borders: Entrenched Issues Exposed By Covid-19, Richmond B. Wrinkle

Georgia Journal of International & Comparative Law

No abstract provided.

Savoring And The Experiential Advantage: Savoring Beliefs Determine Consumer Happiness From Experiential Versus Material Purchases, Charlene Chu

Business Faculty Articles and Research

Consumer research finds that people derive greater enduring happiness from discretionary spending on experiential purchases (events that they personally encounter or live through) than material purchases (tangible objects that can be obtained and kept in their possession). While research in this area has contributed to our understanding of this “experiential advantage” by examining the underlying psychology of this phenomenon, individual differences in the experiential advantage have received less attention. The present investigation examines whether individual differences in savoring capacity affect the subjective well-being that consumers derive from experiential vs. material purchases. This research finds that the self-rated ability to savor …

Growth Hormone Signaling Shapes The Impact Of Environmental Temperature On Transcriptomic Profile Of Different Adipose Tissue Depots In Male Mice., Augusto Schneider, Berta Victoria, Maria Isabel Schiavon Cousen, Yimin Fang, Samuel Mcfadden, Justin Darcy, Adam Gesing, Erin R Hascup, Kevin N Hascup, Andrzej Bartke, Michal M Masternak

Articles

Growth hormone receptor knockout (GHRKO) mice are smaller, long living, and have an increased metabolic rate compared with normal (N) littermates. However, it is known that thermoneutral conditions (30-32°C) elicit metabolic adaptations in mice, increasing the metabolic rate. Therefore, we hypothesized that environmental temperature would affect the expression profile of different adipose tissue depots in GHRKO mice. For this, N (n = 12) and GHRKO (n = 11) male mice were maintained at 23 or 30°C from weaning until 11 months of age. RNA sequencing from adipose tissue depots (epididymal-eWAT, perirenal-pWAT, subcutaneous-sWAT, and brown fat-BAT) was performed. Thermoneutrality increased body …

Growth Hormone Signaling Shapes The Impact Of Environmental Temperature On Transcriptomic Profile Of Different Adipose Tissue Depots In Male Mice., Augusto Schneider, Berta Victoria, Maria Isabel Schiavon Cousen, Yimin Fang, Samuel Mcfadden, Justin Darcy, Adam Gesing, Erin R Hascup, Kevin N Hascup, Andrzej Bartke, Michal M Masternak

Articles

Growth hormone receptor knockout (GHRKO) mice are smaller, long living, and have an increased metabolic rate compared with normal (N) littermates. However, it is known that thermoneutral conditions (30-32°C) elicit metabolic adaptations in mice, increasing the metabolic rate. Therefore, we hypothesized that environmental temperature would affect the expression profile of different adipose tissue depots in GHRKO mice. For this, N (n = 12) and GHRKO (n = 11) male mice were maintained at 23 or 30°C from weaning until 11 months of age. RNA sequencing from adipose tissue depots (epididymal-eWAT, perirenal-pWAT, subcutaneous-sWAT, and brown fat-BAT) was performed. Thermoneutrality increased body …

A Preliminary Report: The Hippocampus And Surrounding Temporal Cortex Of Patients With Schizophrenia Have Impaired Blood-Brain Barrier, Eric L. Goldwaser, Randel L. Swanson, Edgardo J. Arroyo, Venkat Venkataraman, Mary C. Kosciuk, Robert G. Nagele, L. Elliot Hong, Nimish K. Acharya

Rowan-Virtua Research Day

Schizophrenia (SZ) is one of the most severe forms of mental illness, yet mechanisms remain unclear. A widely established brain finding in SZ is hippocampal atrophy, and a coherent explanation similarly is lacking. Epidemiological evidence suggests increased cerebrovascular and cardiovascular complications in SZ independent of lifestyle and medication, pointing to disease-specific pathology. Endothelial cell contributions to blood-brain barrier (BBB) compromise may influence neurovascular unit and peripheral vascular function, and we hypothesize that downstream functional and structural abnormalities may be explained by impaired BBB.

The Brodmann Area 39/40 Of The Brain In Alzheimer’S, Mild Cognitive Impairment, And No Cognitive Impairment Subjects At Advanced Age Demonstrate Comparable Levels Of Blood-Brain Barrier Breach, Dhara Rana, Forum Mangrola, Randel L. Swanson, Venkat Venkataraman, David A. Bennett, Zoe Arvanitakis, David Libon, Robert Nagele, Nimish Acharya

Rowan-Virtua Research Day

• Alzheimer’s disease (AD) is one of the most common form of dementia

• Mild cognitive impairment (MCI), specifically amnestic subtype, more likely to progress to AD

• Pathogenesis Theories:

• o Accumulation of amyloid-beta peptides and neurofibrillary tangles containing hyperphosphorylated neuronal tau protein
• o Blood Brain Barrier (BBB) dysfunction is associated with AD pathogenesis

• Brodmann area 39/40: regions of parietal cortex are responsible for language, spatial cognition, memory retrieval, attention, phonological processing, and emotional processing

• Hypothesis: An increased BBB permeability in Brodmann area 39/40 of AD and age-matched MCI and no cognitive impairment (NCI) subjects

Racial Disparity In Health Insurance Acquisition In The State Of California, Florence Jill Polina

Theses

Racial disparity continues to be a struggle in America. The main purpose of this project was to determine whether there is a relationship between race and the acquisition of health insurance in adult residents of California who are younger than 65 years old. Through secondary data gathering, analysis of an existing racial disparity in health care insurance acquisition was accomplished. The results of the project indicate that a relationship exists between race and health insurance acquisition, thereby promoting an opportunity to determine hindering factors and discuss recommendations that can help to alleviate them.

Exploring The Effects Of A Nurse Mentorship Program On Career Satisfaction And Retention, Jennifer Smith

DNP and Student Works

Global statistics have shown there is a major nursing shortage. It is imperative to stabilize the nursing workforce as the healthcare continuum continues to grow. Nurse career satisfaction is related to nurses' overall intent to stay. Newly licensed registered nurses are leaving healthcare settings at disturbing rates. With the increased need and the current shortages, the nursing profession is unequipped to meet the needs of the growing population. The purpose of this project is to increase nurse career satisfaction and intent to stay with the organization through the implementation of a nurse mentorship program for newly licensed registered nurses with …

Southern Adventist University Commencement Program May 2022, Southern Adventist University

Commencement Programs

Program for Southern Adventist University Winter 2022 graduation. The commencement service took place at the Iles Physical Education Center on May 8, 2022.

Nsu Health Professions Division 2021-2022 Course Catalog, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Up In Smoke: Why Regulating Social Media Like Big Tobacco Won’T Work (Yet!), Ian Mckay

Notre Dame Law Review

Lawmakers, pundits, and tech executives’ assertion that social media should be regulated like tobacco in order to protect American teenagers is oversimplistic. While the comparison makes for a good sound bite for the press, the argument disregards the inherent differences between regulating a physical product that has no constitutional protection and a virtual product that can implicate both users’ and social media companies’ First Amendment rights. This paper will identify and analyze some of the main pillars of the tobacco regulatory scheme and apply them to social media products. In Part I, I will define social media and provide a …

Challenges Experienced By Rural Informal Caregivers Of Older Adults: A Scoping Review, Jon Shuffler

Social Work Theses - Archive

Purpose: The purpose of this study was to document the state of the literature regarding the challenges experienced by rural informal caregivers of older adults in the United States. Methods: A scoping review of peer-reviewed academic articles published through December 1, 2021, was conducted, utilizing the scoping review framework of Arksey and O’Malley (2005). The initial search resulted in 1,255 articles for review, of which 12 studies were included for the final review. Results: Thematic content analysis was utilized to identify emerging themes of challenges experienced by rural informal caregivers of older adults. The identified themes of challenges include a …

Gender Differences In Perception Of Dyspnea And Its Relation To Muscle Weakness, Functional Status, Disability In Activities Of Daily Living, And Depression In Adults With Heart Failure—A Secondary Analysis, Michelle Minh Tran

2022 Spring Honors Capstone Projects - Archive

Although Heart Failure (HF) can occur in both women and men, some studies have shown that both genders do not present the same outcomes; however, there is an underrepresentation of the effect of gender on the relationship of HF and changes in activities of daily living. This study compared the effects of gender on dyspnea and other variables to determine differences between symptoms, disability, and other relationships. A secondary analysis of a cross-sectional descriptive study was conducted with 186 patients who were told to perform several tests to evaluate muscle weakness, functional status, depression, and disability. Instruments such as the …

Global Developments In Social Prescribing, Daniel F. Morse, Sahil Sandhu, Kate Mulligan, Stephanie Tierney, Marie Polley, Bogdan Chiva Giurca, Siân Slade, Sónia Dias, Kamal R. Mahtani, Leanne Wells, Huali Wang, Bo Zhao, Cristiano Emanuel Marta De Figueiredo, Jan Joost Meijs, Hae Kweun Nam, Kheng Hock Lee, Carolyn Wallace, Megan Eliott, Juan Manuel Mendive, David Robinson, Miia Palo, Wolfram Hermann, Rasmus Østergaard Nielsen, Kerryn Husk

Applied Computer Science | Faculty Scholarship

Social prescribing is an approach that aims to improve health and well-being. It connects individuals to non-clinical services and supports that address social needs, such as those related to loneliness, housing instability and mental health. At the person level, social prescribing can give individuals the knowledge, skills, motivation and confidence to manage their own health and well-being. At the society level, it can facilitate greater collaboration across health, social, and community sectors to promote integrated care and move beyond the traditional biomedical model of health. While the term social prescribing was first popularised in the UK, this practice has become …

Reducing Medication Non-Adherence With Improved Health Literacy Interventions: An Evidence-Based Practice Quality Improvement Project, Unity Wiles

DNP Projects

Introduction

Health literacy is the ability to obtain, process, and understand basic health information and services needed to make appropriate healthcare decisions and follow instructions for treatment. Patients with low health literacy have been predicted to have poor health outcomes. The inclusion of the single-item literacy tool into the admission process of this project involved the patient-centered-care characteristics of improved patient experience, lower health cost, improved clinical experience, and better outcomes.

Purpose

The National Action Plan to improve Health Literacy seeks to engage organizations, professionals, policymakers, communities, individuals, and families in a linked multi-sector effort to improve health literacy. Low …

Office Of Community Engagement Newsletter, May 2022, University Of Northern Iowa. Office Of Community Engagement.

Community Engagement Newsletter

Contents:

--- UNI Engaged: Stories of Impact
--- Award Recognition
--- Service-Learning Institute
--- Civic Action Plan 2.0 - Input Requested
--- Upcoming Events
--- In Other News

Effects Of Increased Levels Of Relaxin Hormone In Women During Pregnancy In Relation To Spondylolisthesis: A Literature Review, Joselin R. Guerrero Rapalo

Honors Theses

No abstract provided.