Digital Commons Network^™

Inflammatory Markers As A Predictor Of Postmenopausal Osteoporosis, Asma Al Salmani, Asma Al Shidhani, Nouf M. Al-Alawi, Arwa A. Al Sulaimi, Maha A. Al-Hashemi

Sultan Qaboos University Medical Journal

Objectives: Postmenopausal osteoporosis is a progressive metabolic bone disease resulting from oestrogen deficiency. Due to the silent nature of the disease, there is an urgent need for a simple, early predictive marker. This study aimed to assess the potential of three factors—neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR) and platelet-to-lymphocyte ratio (PLR)—as inflammatory markers of bone mineral density (BMD) loss. Methods: A retrospective cross-sectional study was conducted among 450 postmenopausal Omani women undergoing dual-energy X-ray absorptiometry at the Sultan Qaboos University Hospital, Muscat, Oman, from January 2017 to December 2019. The participants were allocated to groups based on lumbar spine BMD …

Metabolic Requirement For Got2 In Pancreatic Cancer Depends On Environmental Context, Samuel A Kerk, Lin Lin, Amy L Myers, Damien J Sutton, Anthony Andren, Peter Sajjakulnukit, Li Zhang, Yaqing Zhang, Jennifer A Jiménez, Barbara S Nelson, Brandon Chen, Anthony Robinson, Galloway Thurston, Samantha B Kemp, Nina G Steele, Megan T Hoffman, Hui-Ju Wen, Daniel Long, Sarah E Ackenhusen, Johanna Ramos, Xiaohua Gao, Zeribe C Nwosu, Stefanie Galban, Christopher J Halbrook, David B Lombard, David R Piwnica-Worms, Haoqiang Ying, Marina Pasca Di Magliano, Howard C Crawford, Yatrik M Shah, Costas A Lyssiotis

Faculty, Staff and Student Publications

Mitochondrial glutamate-oxaloacetate transaminase 2 (GOT2) is part of the malate-aspartate shuttle, a mechanism by which cells transfer reducing equivalents from the cytosol to the mitochondria. GOT2 is a key component of mutant KRAS (KRAS*)-mediated rewiring of glutamine metabolism in pancreatic ductal adenocarcinoma (PDA). Here, we demonstrate that the loss of GOT2 disturbs redox homeostasis and halts proliferation of PDA cells in vitro. GOT2 knockdown (KD) in PDA cell lines in vitro induced NADH accumulation, decreased Asp and α-ketoglutarate (αKG) production, stalled glycolysis, disrupted the TCA cycle, and impaired proliferation. Oxidizing NADH through chemical or genetic means resolved the redox imbalance …

Does Well-Being Moderate The Association Of Harm Avoidance With Cognitive Decline, Christopher Reed

LSU Master's Theses

The Dual-Factor Model of mental health highlights the need to consider both constructs associated with psychopathology and subjective well-being in relation to clinical outcomes. Harm avoidance, which is associated with behavioral inhibition, has been negatively associated with cognitive change. While subjective well-being has been positively associated with cognition. The current study aimed to examine both constructs in a single model to examine well-being as a moderator of the association of harm avoidance with cognitive decline. A sample of 728 older adults from the Rush University Memory and Aging Project was used. Participants completed batteries of questionnaires and neuropsychological tests at …

Adverse Childhood Experiences (Aces) Education Implementation For Graduate Nursing Students, Courtney Kovachevich

Dissertations

Chronic conditions are a leading cause of death and disability in the United States (U.S.). Adverse Childhood Experiences (ACEs) are risk factors for chronic conditions and death; however, screening and assessment of ACEs do not occur in primary care settings. A barrier to screening is a lack of knowledge and education during providers’ didactic courses. To address this barrier, a standardized education tool was implemented into a midwestern public graduate nursing Doctor of Nursing Practice (DNP) curriculum. The design was a Quality Improvement (QI) project with a descriptive cohort design and purposive sample. The inclusion criteria were students in the …

Fall Risk Screening In Community Dwelling Elders Through Self-Assessment, Natasha Dickinson

Dissertations

Problem: Falls and fall-related injuries are considered preventable. Fall risk screening is crucial in the prevention of falls and fall-related injuries in community dwelling elders. The purpose of this quality improvement project was to initiate the use of the CDC’s self-rated Fall Risk Questionnaire (Self-rated FRQ) screening tool and CDC-guided education in a cohort of community dwelling seniors at a geriatric agency.

Method: A pre-post assessment was conducted on community dwelling seniors 65-years and older. A convenience sample of eligible participants (N=16) was taken from a geriatric agency in a Midwest, metropolitan city. Fall incidence and fall-related injuries …

Evaluating The Effectiveness Of Implementing Depression Screenings With Uninsured African American Adults, Pamela Talley

Dissertations

Problem: Uninsured African Americans are underdiagnosed and often untreated for depression. Individuals usually do not present to their primary care provider with a complaint of depressed mood, however, may report symptoms such as decreased energy, general body aches, digestive concerns, somatic complaints, or older adults' memory or cognitive problems. The purpose of this quality improvement pilot project was to examine the results of the implementation of a depression screening (PHQ-9) in a primary care setting for uninsured adults for detection, diagnosis, and treatment of depression in African American clients.

Results: The PHQ-9 screening questionnaire was given to 100% (N …

Evaluating Mindfulness On Loneliness In An Older Adult Population, Jessica Tieskoetter

Dissertations

Problem: Loneliness is a widespread public health concern and has negatively impacted mortality and health outcomes among older adults. This quality improvement project’s purpose was to evaluate mindfulness on loneliness and quality of life among adults aged 65 years and older, participating in a weekly befriending socialization program.

Methods: A descriptive cohort design was utilized to assess loneliness pre-and post-implementation of a mindfulness telephone line over three months. A convenience sample of 22 older adults enrolled in a befriending socialization program was used. The Iowa Model of Evidence-Based Practice framework was applied to guide the implementation of a practice change …

Implementation Of A Protocol Nurse In The Emergency Department, Marissa Kramer

Dissertations

Abstract

Problem: Increased wait times and extended length of stay (LOS) of patients in the Emergency Department (ED) are contributing to overcrowding, burdening EDs worldwide. A nurse can initiate patient care using protocol order sets while a patient is in the waiting room; however, triage nurses are often too busy to complete these orders. Scheduling a nurse to complete these protocol order sets could reduce ED overcrowding and patient LOS.

Method: A convenience sample was used to retrospectively chart review and collect data utilizing an excel spreadsheet with patients 40 years of age and older with a chief complaint of …

The Mission System: An Electronic Health Record For Medical Treatment In Guatemala, Tawniece M. Curry

Dissertations

Abstract

Problem: The introduction of an electronic health record (EHR) system has become an essential component in monitoring and tracking patient information in most developed countries but are difficult to implement in underdeveloped countries. Guatemala is a country with poor health care and limited resources for patient tracking and monitoring. An organization in Guatemala, Nursing Heart Inc. (NHI), provides care to over 40 underserved rural communities but lacks the ability to monitor and track patient information. In order for NHI to properly monitor and evaluate their programs and track patients’ continuity of care, the introduction of an EHR system is …

Preventing Falls Using Evidence-Based Interventions In A Long-Term Care Facility, Pibi Bouda

Dissertations

Falls and fall-related injuries are common and significant health issues among older adult patients living in Long-Term Care (LTC) facilities, especially those with memory impairment. The current quality improvement (QI) project aimed to educate staff members and implement a structured 4 Ps hourly rounding (HR) protocol on an LTC facility pilot unit in Missouri. The project was implemented in a memory care unit housing older military veterans patients in a large metropolitan area of Missouri. The project question that guided the intervention was: In older residents living in a memory care unit of an LTC facility, what is the impact …

Institutionalized Zakāh In Addressing Well-Being Problems In Nonmuslim Majority Sri Lanka, Abdul Rauff Salithamby, Zulkarnain A. Hatta, Adi Fahrudin

Journal of King Abdulaziz University: Islamic Economics

Institutionalized zakāh has long been a decisive tool that provides various types of support to addressing a variety of well-being problems of the Muslim community in Sri Lanka, a country where such a community is a minority. Being significantly successful to empowering the underprivileged of the community, the zakāh has also faced challenges that negatively impacted its effective functioning. This study aimed to investigate institutionalized zakāh‟s multiple support, identifying its challenges and suggesting some recommendations to make its‟ role more effective. This is an exploratory study used qualitative data collected through interviews with five zakāh institutions in the Eastern part …

The Regulation Of Oxidative Stress In Age-Related Diseases, Jesica Burkhart

Theses and Dissertations

Oxidative stress and mitochondrial dysfunction have been linked to multiple age-related diseases including common neurodegenerative diseases Alzheimer's disease (AD) and Parkinson’s disease (PD). A gene found to regulated oxidative stress and aging is a stress response gene p38 MAPK (p38K). Oxidative stress arises when the over production of reactive oxygen species (ROS) from within the cell or from environmental stimuli outweighs its clearance by antioxidants. This cascade leads to DNA damage, mitochondrial damage, and cell death. Mitochondrial dysfunction and oxidative stress are markers for biological aging. As we age mitochondrial DNA becomes more sensitive to damages and mutations. When the …

Utilizing Heart Rate And Rpe To Prescribe Cycle Ergometer Hiit In Older Adults: A Feasibility Study, Christopher J. Keating, Pedro Ángel Latorre Román, José Carlos Cabrera Linares, Ana De La Casa Pérez, Juan Antonio Párraga Montilla

International Journal of Exercise Science

International Journal of Exercise Science 15(4): 896-909, 2022. Previous research has provided evidence that aerobic HIIT exercise can induce important physiological adaptations and elicit improvements in health and fitness parameters. However, most of the research has taken place in a laboratory setting with specialized equipment and monitoring devices. It begs the question, is HIIT accessible to the general aging population? The objective of the current research was to employ an age-predicted HRmax to prescribe a minimally invasive 4x4 cycle ergometer HIIT protocol. Ten participants (age: 64.2 ± 6.1) completed a non-weight-bearing cycle ergometer protocol for 6 weeks. Significant Pearson correlations …

The Experiences Of Older Formerly Incarcerated Adults In A Specialized Reentry Program During The Covid-19 Pandemic, Robin O'Hanlon, Jessica Broome

Publications and Research

A growing area of concern among prison reform advocates and human rights activists is the “greying prison population” or the continuous, unified growth in the number of older incarcerated individuals. Older individuals experience an accelerated aging process while incarcerated, but are less likely to reoffend upon release. While the aging prison population has in recent years become a focus of criminological and gerontological scholars, the lived experience of older formerly incarcerated individuals during the reentry process remains understudied. Using a qualitative approach, this cohort study seeks to further elucidate the unique needs, beliefs, and perceptions of this population within the …

Study On Extraction Process Of Methylated Catechin From Zijuan Tea By Response Surface Methodology, Li Yu-Qian, Gao Chuang-Chuang, Li Ming-Chao, Li Xiao-Lei, Hao Qian

Food and Machinery

Objective:optimizing the extraction process of methylated catechin from Zijuan tea.Methods:Using acid ethanol as extraction solvent, based on three single factor experiments, the extraction time, extraction temperature and liquid-solid ratio were used to investigate the interaction of the above three factors on the extraction rate of methylated catechin from Zijuan tea.Results:The optimum extraction conditions were as follows: extraction time 100 min, extraction temperature 75 ℃, solid-liquid ratio(m Zijuan tea∶VSolvent)1∶74(g/mL); under these conditions, the mass concentration of methylated catechin in the extract could reach 26.7 mg/g, and the relative error with the verification value was 1.48%.Conclusion:HPLC and …

Visit To A Nursing School In Bangladesh: Shared Bonds That Transcend Culture, Suzanne Parkman Phd, Rn, Cne

School of Nursing

This is a description of an educational collaboration with a nursing school in Bangladesh. It includes the history of nursing education, philosophy, curriculum plan, grading, and the experience of teaching.

Comprehensive Pain Assessment For Veterans In Long-Term Care., Christopher Jenkins

Doctor of Nursing Practice Papers

Background Literature supports the need for comprehensive pain assessment (CPA) in long-term care facilities. CPAs provide valuable information for facility providers and health care staff to intervene appropriately regardless of cognitive ability. Without the use of such tools, pain can go undertreated or ignored for this underserved population causing undue suffering and poor quality of life. Chronic pain perpetuates an endless cycle of immobility, falls, injury, functional decline, and eventual death for this population.

Purpose: A CPA was implemented, evaluated, and integrated into the care processes in a long-term care facility for veterans

Method: The IHI improvement model with a …

Older Adult Healthcare Utilization Patterns And Receptiveness Towards Healthier Sg Initiative, Micah Tan, Grace Cheong, Wensi Lim, Paulin T. Straughan

ROSA Research Briefs

The Healthier SG (HSG) initiative was launched by Health Minister Ong Ye Kung in March 2022. HSG marks a distinct departure from existing healthcare models as under this new initiative, greater emphasis is placed on preventive healthcare rather than reactive treatments. This shift in approach is envisioned to have a significant influence on the healthcare system in Singapore – for instance, by focusing on “health care” rather than on “sick care” it is hoped by some that this new model will discourage the ‘over-service’ of patients by doctors in Singapore (Lim, 2022). An integral component of the HSG initiative is …

Understanding Student Perspective’S Around Diversity, Equity, And Inclusion Within The School Of Social Work, Anna Yelick, Dee Sherwood

Assessment Grants

Diversity, equity, and inclusion (DEI) has become a prominent fixture within the social work profession, with educational and professional organizations paying closer attention to issues related to DEI. The Council on Social Work Education (CSWE), the governing body for accrediting social work education programs, has required social work programs to demonstrate a commitment to DEI in their implicit curriculum. Therefore, the School of Social Work is interested in understanding student perspectives and experiences of DEI efforts particularly within the implicit curriculum.

Longitudinal Associations Of Perceived Mastery And Constraints With Coping And Their Implications For Functional Health For Aging Adults, Masahiro Toyama, Joel M. Hektner

Psychology Faculty Research

The present study examined longitudinal associations of distinct dimensions of perceived control (i.e., perceived mastery and constraints) with approach and avoidance coping relating to functional health for aging adults, which had not been well studied previously. Using data from two waves of Midlife in the United States (N = 4,963, whose mean age was 55.4 [SD = 12.5]), a longitudinal path model was analyzed for direct and indirect effects among perceived mastery and constraints, approach and avoidance coping, and functional limitations. Bidirectional associations were observed between perceived mastery and approach coping and between perceived constraints and avoidance coping. …

Education Regarding Advance Directives Improves The End-Of-Life Choices Documentation In Heart Failure Patients, Phebe Hagins Wright

Doctor of Nursing Practice Projects

Background: Heart failure affects the lives of more than 6 million people in the United States and outpatient heart failure clinics offer an opportunity to educate patients while providing evidence-based care. A needs analysis revealed that many heart failure patients do not have an advance directive (AD) on file.

Purpose: The DNP project aims to implement an educational program that provides the tools and knowledge to heart failure patients to assist patients in determining their end-of-life care goals and allow them to document these goals in the Five Wishes document.

Methods: This quality improvement project consisted of a didactic educational …

Implementing A Type 2 Diabetic Comprehensive Educational Website For Health Care Providers In A Rural Health Clinic, Jeanette Caddell

Doctor of Nursing Practice Projects

Background: Type 2 diabetes mellitus (T2DM) can lead to multiple health problems if not treated properly. Research has shown that if T2DM patients have proper education and continued follow-up care from their health care provider, their prognoses are better. The problem is many health care providers (HCP) lack knowledge in educating patients about T2DM.

Purpose: This study aimed to assess HCPs’ knowledge of evidence-based practice measures to educate patients diagnosed with T2DM and provide education via an educational website.

Methods: This quality improvement project consisted of a comprehensive educational website offered to HCPs to increase their knowledge base on educating …

2022-2023 Fall Bulletin, University Of Mississippi Medical Center

Bulletins/Catalogs

2022-2023 Fall Bulletin

2022 - 2023 University Catalog, Loma Linda University

University Catalog (2005 - present)

This is a one-year CATALOG, effective beginning Summer Quarter 2022.

Volume 112, Number 1, July 2022

External Funding Bulletin, January - June 2022, Uno Office Of Research And Creative Activity

Sponsored Programs Bulletins

No abstract provided.

University Of Central Florida Undergraduate Catalog, 2022 - 2023, University Of Central Florida

UCF Catalogs

No abstract provided.

Evaluating The Extent Of Fall Prevention Knowledge Of Direct Care Clinicians In A Post-Acute Hospital Setting: A Quality Improvement Initiative, Joseph Henry Mitchell Jr

Doctor of Nursing Practice Projects

Background: Events, such as falls, continue to maintain permanence in countless public health settings and organizations, attributing to unnecessary resource utilization. Proven methods for mitigating fall occurrences transpire through reliable fall education and by creating programs that directly impact these incidents. These agendas are essential and can lessen undue stress, obligations, and associated fiscal liability.

Purpose: This DNP project aimed to ascertain and expand unit nurses' fall prevention strategy knowledge in a long-term acute care hospital, bringing awareness of evidence-based practices through a learning addendum.

Methods: This program, based on a descriptive, quasi-experimental, pre-, and post-analysis, strategically …

Improving Workflow Efficiency In A Medical Clinic Utilizing A Competency Evaluation Tool With Skills Checklist, Jillian England Johnson

Doctor of Nursing Practice Projects

Background: Checklists are commonly used in many healthcare settings to validate one’s competency in a skill or task. Competency is essential to help reduce human errors and prevent patient harm, improving patient outcomes while carrying out evidence-based care.

Purpose: The purpose of this DNP project was to improve patient care, patient care outcomes, and workflow efficiency in a charitable clinic by identifying strengths and opportunities for growth among the staff and volunteers through a competency evaluation tool utilizing a skills checklist.

Methods: This quality improvement project included implementing a competency evaluation tool with a skills checklist for staff and volunteers …

Training Sexual Assault Nurse Examiners (Sane) And Patient Advocates To Improve Utilization Of The Alabama Crime Victims Compensation Commission (Acvcc) Program For Sexual Assault Victims, Erica Starling

Doctor of Nursing Practice Projects

Background: Sexual assault is a nationwide problem that often goes unreported. According to the Rape, Abuse and Incest National Network (RAINN), every 68 seconds an American is sexually assaulted. One out of every six women has been a victim of sexual assault in their lifetime. Sexual violence has long-term effects on victims including post-traumatic stress disorder, suicidal ideations and/or attempted suicide, substance use disorder, work and/or family life struggles, unplanned pregnancy, and/or sexually transmitted infections (STI).

Purpose: The purpose of this project is to improve the utilization of the Alabama Crime Victims Compensation Commission Program (ACVCC) for victims …

A Clinical And Community Linkage Benefitting Patients With Chronic Conditions, David B. Clapp

Doctor of Nursing Practice Projects

Background: Connecting healthcare clinics and community resources can improve the health of patients. It is shown that this type of linkage is an effective approach to addressing health concerns and to potentially prevent long-term health issues.

Purpose: The purpose of the DNP project is to promote and provide a clinical-community linkage at a local specialty clinic to determine if the providers find that offering community resources to patients increases their perception of quality of care provided.

Methods: Utilizing a guideline set forth by the CDC, providers within a specialty clinic were provided with a pre-test to determine if their current …