Digital Commons Network^™

Cognitive Disease And Age-Related Cognitive Decline, Darashagam Nahal

Stimulus: A Medical Humanities Journal

A literature review on cognitive disease and age-related decline in cognitive functioning.

Exogenous Ketone Supplements For Reducing Anxiety-Related Behavior, Csilla Ari D'Agostino, Dominic Paul D'Agostino

USF Patents

Methods of treating anxiety disorders or reducing anxiety-related behaviors. The methods include administering a therapeutically effective amount of ketone supplementation, such as butanediol, ketone esters (e.g., 1,3-butanediol-acetoacetate diester) and/or ketone salts (e.g., beta-hydroxybutyrate-mineral salt), chronically, sub-chronically, or acutely, with or without admixture with a medium chain triglyceride or in combination. It was determined herein that ketone supplementation reduced anxiety in rats on elevated plus maze as measured by less entries to closed arms, more time spent in open arms, more distance travelled in open arms, and delayed latency to entrance to closed arms, when compared to control. Along with reducing …

Management Of Constipation In Hospitalized Patients, Gregory S Sayuk, Qi T Yu, Corey Shy

2020-Current year OA Pubs

Constipation is frequently encountered in hospital settings and can have potentially serious consequences yet is often underrecognized and undertreated. Opioid-induced constipation is a common cause of constipation in hospitalized patients. Opioids induce constipation through agonistic effects on enteric µ-opioid receptors. This review aims to provide insight on the identification and management of constipation in inpatient settings, with a particular focus on opioid-induced constipation. Constipation assessment should be routinely initiated at hospital admission and can be facilitated by thorough symptom assessments; relevant patient history, including recent medication use; physical examination; and patient assessment tools developed to evaluate the impact of constipation. …

Students’ Perceptions Of The Usability Of The Library At Tshwane University Of Technology, Polokwane Campus, Kwetepe Julious Malatji Phd

Library Philosophy and Practice (e-journal)

Students’ perceptions of the usability of libraries is very important as they can help to put into perceptive how students relate to libraries and how they use them. For this reason, this study aimed to investigate students’ perceptions of the usability of the library at the Tshwane University of Technology, Polokwane Campus. Quantitative and qualitative research approaches were followed. The constructivist learning theory was adopted as a theoretical framework for the study. The research design was a case study. To obtain sampling units of students, Stratified random sampling and systematic random sampling were applied. In the case of the library …

The Effectiveness Of Serotonin And Tricyclic Antidepressants In Tinnitus Management: A Rapid Review, Dr. Emilie Vos, Dr. Nannette Nicholson, Melinda Johnson, Dr. Karah Gottschalk

Internet Journal of Allied Health Sciences and Practice

Background: Tinnitus can be defined as a health condition characterized by the perception of sound, either in the head and/or ears, in the absence of any external acoustic stimulus. Perception is often quantified by self-report, or the use of patient reported outcome measures (PROMs). The purpose of this rapid review was to evaluate the level and quality of evidence regarding the use of serotonin and norepinephrine reuptake inhibitors (SNRI), selective serotonin reuptake inhibitors (SSRI), and tricyclic antidepressants as measured by tinnitus patient-reported outcome measures (PROMs) and/or Visual Analog Scales (VAS). Methods: The Cochrane Rapid Review guidelines were followed. The PICO …

Examining The Relationship Between Counselor Professional Identity And Burnout, Jessica Gaul

Antioch University Dissertations & Theses

This study examines counselor professional identity and burnout for clinical mental health counselors. The population of focus included licensed or license-eligible Clinical Mental Health Counselors, who were post-grad (N=53). Participants then completed the Professional Identity Scale in Counseling - Short Form and the Maslach Burnout Inventory–Human Services Survey. When examining the findings regarding the relationship between Counselor Professional Identity and Burnout for this study, the initial observation revealed the validity and applicability of the MBI-HSS to clinical mental health counselors. Though a relationship between Burnout and Counselor Professional Identity was not identified, relationships between sub-scale items were noteworthy. Implications for …

Social Connectedness Between Family Caregivers And Older Adults Living In Long-Term Care Homes In The Context Of Covid-19, Anna Garnett, Hannah Pollock, Natalie Floriancic, Kristin Prentice, Lorie Donelle Phd, Rn, Fcan, Carri Hand, Abe Oudshoorn, Yolanda Babenko-Mould, Cheryl Forchuk

Publications

The coronavirus disease (COVID-19) pandemic and resulting restrictions on physical access to long-term care homes culminated in health declines for older adults living there and their families. Knowledge gaps exist regarding maintaining social connectedness when physically separated. The study aimed to explore family members' perceptions of the impact that restrictions on physical access to long-term care homes had on the experience of social connectedness between family members and older adults living in long-term care. The method used was a qualitative description, using in-depth semi-structured interviews. Themes arising from inductive qualitative content analysis of 21 interviews with family members included: (a) …

Effects Of Computer-Based Cognitive Training Combined With Physical Training For Older Adults With Cognitive Impairment: A Four-Arm Randomized Controlled Trial, I-Ching Chuang, Hui-Yan Chiau, Wan-Wen Liao, Yih-Ru Wu, Chih-Hung Chang, Ching-Yi Wu

2020-Current year OA Pubs

OBJECTIVE: Combined physical (PHY) and cognitive (COG) training in sequential (SEQ) and simultaneous (SIMUL) sessions may delay the progression of cognitive impairment. To date, no study has directly compared in older adults with cognitive impairment the effects of COG training, PHY training, SEQ motor-cognitive training and SIMUL motor-cognitve training on specific indices of cognitive performance and activities of daily living (ADL). The purpose of this study was to determine whether SEQ and SIMUL motor-cognitive training can improve treatment outcomes compared with PHY or COG training alone. We also aimed to compare the effects of SEQ versus SIMUL motor-cognitive training on …

Association Between Alcohol Consumption And Ectopic Fat In The Multi-Ethnic Study Of Atherosclerosis, Richard Kazibwe, Parag A Chevli, Joni K Evans, Matthew Allison, Erin D Michos, Alexis C Wood, Jingzhong Ding, Michael D Shapiro, Morgana Mongraw-Chaffin

Faculty, Staff and Students Publications

Background The relationship between alcohol consumption and ectopic fat distribution, both known factors for cardiovascular disease, remains understudied. Therefore, we aimed to examine the association between alcohol consumption and ectopic adiposity in adults at risk for cardiovascular disease. Methods and Results In this cross-sectional analysis, we categorized alcohol intake among participants in MESA (Multi-Ethnic Study of Atherosclerosis) as follows (drinks/day): <1 >(light drinking), 1 to 2 (moderate drinking), >2 (heavy drinking), former drinking, and lifetime abstention. Binge drinking was defined as consuming ≥5 drinks on 1 occasion in the past month. Visceral, subcutaneous, and intermuscular fat area, pericardial fat volume, and …

Factors Affecting Rural Women’S Involvement In Physical Activity In Ghana, Alice Quainoo, T. A. Loeffler

International Journal of Physical Activity and Health

A qualitative study approach was used to explore the factors affecting rural women’s involvement in physical activity in Ghana. Most prior research has been done in African urban areas thus, neglecting the rural areas. Purposive sampling and a semi-structured interview method were used to interview nine women aged 40-60 years living in three rural areas in the central region of Ghana. The interviews were conducted by phone, translated, transcribed, and then coded using NVivo software package. The constant comparative method was used to analyze the data. The data presented eight enablers and five barriers to physical activity involvement for rural …

Impact Of A Novel Multi-Specialist Telemedicine Consultation Program Model Of Care For Homebound Older Adults, Samir K. Sinha Dr, Kristina Marie Kokorelias, Nicoda Foster, Pauline Kabitsis, Alfiya Mukharyamova, Mary Ann Hamelin, Nga Truong, Anna Grosse Dr, Janny Lee

Journal of Geriatric Emergency Medicine

BACKGROUND: In 2015, a centralised Multi-Specialist Telemedicine (TM) Consultation Program was established to improve access to specialist care and enhance continuity of care for homebound older adults in Toronto, Canada. Community-dwelling patients were referred to the program by their primary care providers (PCP), treating specialists, and inpatient physicians for specialist-led post hospital discharge follow-up care. A clinical nurse specialist (CNS) thereafter collaborated with hospital-based consulting specialists, utilizing videoconferencing technology to facilitate consultations and follow-up visits for homebound patients

METHODS: We conducted a retrospective observational study of the overall intervention including patient characteristics and the number/type of consultations provided by analyzing …

Screening Patients For Physical Frailty In The Preoperative Phase, Sean V. Pottenger, Amanuel Gebeyehu

Doctor of Nursing Practice (DNP) Student Projects

Background: Frailty is a syndrome characterized by an increased burden of symptoms and higher susceptibility to adverse health, including higher functional decline rates, pressure ulcers, falls, delirium, extended hospital stay, and discharge to assisted living facilities. Screening patients for frailty before undergoing a surgical procedure is recommended to minimize postoperative complications. In the preoperative phase at a midwestern academic hospital, surgical patients are not screened for frailty using a validated screening tool.

Purpose: This project sought to calculate the Clinical Frailty Scale (CFS) score using a novel algorithm. After validating the novel algorithm, this research project predicted that clinicians would …

The Effects Of Sales Surprise On Inventory Turnover: An Empirical Study, Muhammad Yousaf, Bruce Dehning

Accounting Faculty Articles and Research

Sales surprise (SS) is a significant factor in a firm’s inventory turnover (ITO). In order to estimate SS, it is necessary to select an appropriate approach of sales forecasting. The current study’s main purpose is to examine the effects of SS on ITO. The data was gained from the Albertina database from 2017 to 2021, for two sectors: manufacturing and construction. The Czech firms’ panel data was used to estimate sales forecasts by four different methods: (i) sales linear forecast (SLF), (ii) sales change (SCH), (iii) sales growth (SG), and (iv) sales forecast random walk (SRW). The two most accurate …

Overcoming The Inner Critic: The Therapeutic Use Of Self-Portraits With Older Adults, Brenda Echeverry

Expressive Therapies Capstone Theses

Older adults are a growing and vulnerable population who experience discriminatory practices that impact their access to equitable housing, employment, and healthcare which was made even more obvious during the Coronavirus pandemic in the United States. A community engagement project was developed and facilitated by the writer to support older adults with the psychological effects of surviving the pandemic. This project also helped to increase accessibility to expressive arts therapy in the writer’s local community. Expressive arts therapy is an effective and accessible method to support mental health and wellness for people of all ages. Engagement with the arts helps …

Overcoming The Inner Critic: The Therapeutic Use Of Self-Portraits With Older Adults, Brenda Echeverry

Expressive Therapies Capstone Theses

Older adults are a growing and vulnerable population who experience discriminatory practices that impact their access to equitable housing, employment, and healthcare which was made even more obvious during the Coronavirus pandemic in the United States. A community engagement project was developed and facilitated by the writer to support older adults with the psychological effects of surviving the pandemic. This project also helped to increase accessibility to expressive arts therapy in the writer’s local community. Expressive arts therapy is an effective and accessible method to support mental health and wellness for people of all ages. Engagement with the arts helps …

Aptamer-Based Proteomics Measuring Preoperative Cerebrospinal Fluid Protein Alterations Associated With Postoperative Delirium, Simon T. Dillon, Sarinnapha M. Vasunilashorn, Hasan H. Otu, Long Ngo, Tamara Fong, Xuesong Gu, Michele Cavallari, Alexandra Touroutoglou, Mouhsin Shafi, Sharon K. Inouye, Zhongcong Xie, Edward R. Marcantonio, Towia A. Libermann

Department of Electrical and Computer Engineering: Faculty Publications

Delirium is a common postoperative complication among older patients with many adverse outcomes. Due to a lack of validated biomarkers, prediction and monitoring of delirium by biological testing is not currently feasible. Circulating proteins in cerebrospinal fluid (CSF) may reflect biological processes causing delirium. Our goal was to discover and investigate candidate protein biomarkers in preoperative CSF that were associated with the development of postoperative delirium in older surgical patients. We employed a nested case–control study design coupled with high multiplex affinity proteomics analysis to measure 1305 proteins in preoperative CSF. Twenty-four matched delirium cases and non-delirium controls were selected …

The Relationship Between Unmet Medical Needs Awareness And Health Care Utilization In Korean Adults With Social Activity Restriction: A Secondary Analysis Study Using Propensity Score Matching, Jeong Min Yang, Jae Hyun Kim

Journal of Health Research

Background : This study aimed to analyze the relationship between unmet medical needs (UMN) awareness and health care utilization in Korean adults with social activity restriction (SAR).

Method : The 6~8th Korea National Health and Nutrition Examination Survey (KNHANES) was used to analyze 41,720 people among groups aged 19 or older by applying individual weights imposed from the raw data. Weighted logistic regression and Weighted zero-inflated Poisson regression analyzed the relationship. Additional analysis was performed using Propensity Score Matching (PSM) to equalize all variables except UMN.

Results : SAR due to health condition group (1.75 OR) had a higher UMN …

Nursing Panel Presentation: Certification Champion Pilot Project To Increase Rn Specialty Certification Rates, Ari Meyers, Trisha Saul, Miriam Bender

2023 South Division Nursing Research Conference

No abstract provided.

The Mex-Cog Cognitive Assessment Battery: Discriminant Analysis Of The Cognitive Performance Profile In Older Adults, Silvia Mejia-Arango, Sara Aguilar-Navarro, Alberto José Mimenza-Alvarado

School of Medicine Publications

Objective. To analyze the cognitive profile of a clinical sample using the Mex-Cog cognitive battery and establish which cognitive measures and domains contribute most to group separation.

Materials and methods. A group of 145 older adults previously diagnosed with dementia (n= 47), mild cognitive impairment MCI (n= 47), or as cognitively normal (n= 51) were assessed with the Mex-Cog cognitive battery. Six linear discriminant analyses (LDA) were estimated to compare dementia vs. cognitively normal, MCI vs. cognitively normal, and MCI vs. dementia, using ten individual measures and six cognitive domains. We used a leave-one-out cross-validation procedure to evaluate the predictive …

Approved Programs 9-12-23, Angela Brock

Programs Committee (PC)

No abstract provided.

Programs Agenda 9-12-23, Angela Brock

Programs Committee (PC)

No abstract provided.

Ucc Minutes 9-12-23, Angela Brock

UCC Agendas/Minutes

No abstract provided.

The Nursing Process And Allegations Of Malpractice Against Perinatal Registered Nurses In Florida, Genifer Jones Johnson

Dissertations

The nursing process as a foundation of professional nursing practice organizes care around the components of assessment, diagnosis, planning, implementation, and evaluation as required for professional registered nurses by the Florida Nurse Practice Act. Nurses who fail to comply with the Nurse Practice Act risk poor outcomes for their clients, disciplinary action from the State regulatory body, and legal action from the clients. This study was an examination of litigation claims against professional registered nurses in Florida who practice perinatal nursing seeking to identify and categorize allegations of negligence within the components of the nursing process. The expectation of this …

A Socio-Cultural Analysis Of Elder Abuse In A Non-Western Society Of Ghana : Theoretical Approach And (Multi-Stakeholder) Interventions For Elder Justice, Francis Arthur-Holmes

Lingnan Theses (MPhil & PhD)

Research and policy literature on elder abuse and its conceptualisation has been dominated by Western academics and institutions. The conceptualisations in the literature do not adequately capture non-Western perspectives embedded in socio-cultural norms. Empirical studies on prevalence and risk factors of elder abuse are also dominated by Western and Asian scholars. However, research on elder abuse or mistreatment in Africa, to date, remains understudied and thus there is the need for thorough investigation and understanding of the phenomenon. In response, this thesis set out to offer socio-contextual/cultural meaning and understanding of elder abuse in a non-Western society of Ghana. Specifically, …

Do We Need Paradigms? A Mixed Methods Perspective, R. Burke Johnson

Mid-Western Educational Researcher

Point/Counterpoint

The Perceived Level Of Self-Efficacy Of Direct Care Staff Who Complete Person-Centered Care Dementia Training In Long-Term Care Setting, Tammy B. Retalic

Dissertations

Education that enables direct care workers to provide person-centered care approaches to older adults with dementia is necessary to optimize quality of life and reduce unnecessary antipsychotic medication use in long-term care settings. A quasi-experimental repeated measure project design evaluated the effectiveness of a dementia training program (one of several interventions implemented to reduce antipsychotic medication rates) by measuring the perceived level of self-efficacy before the training, immediately after the training and four to six weeks after completing the training.

Using Medicaid Data To Identify Factors That Predict Reinstitutionalization Of Mississippians With Disabilities And Elderly People, Hwanseok Choi

Journal of Public Health in the Deep South

Background: Mississippi Bridge to Independence (B2I) was Mississippi’s Money Follows the Person (MFP) program seeking to rebalance the state’s long-term care system by transitioning Medicaid beneficiaries from institutional living to home- and community-based settings (HCBS). Success of initial transitions has been documented in state cost-savings and participants’ quality of life increases. However, reinstitutionalization poses a challenge to sustaining a positive outcome for the initiative. Purpose: Therefore, the purpose of this research is to identify the underlying causes of participants’ reinstitutionalization. Methods: The Quality of Life (QoL) survey designed by Mathematica Policy Research was used to measure variables in 7 categories. …

Evaluation Of The Electronic Clinical Dementia Rating For Dementia Screening, Rachel L Nosheny, Daniel Yen, Krista Moulder, Connie Mayo, Maureen Mcmillan, John C Morris, Yan Li, Et Al.

2020-Current year OA Pubs

IMPORTANCE: The Clinical Dementia Rating (CDR) is a well-validated instrument widely used to detect and stage dementia due to Alzheimer disease. The digital Electronic Clinical Dementia Rating (eCDR) can be remotely self-administered and automatically scored, with potential to facilitate efficient dementia screening and staging.

OBJECTIVE: To evaluate the association of the eCDR with the CDR and other in-clinic assessments for screening older adults for cognitive impairment.

DESIGN, SETTING, AND PARTICIPANTS: This multisite, cross-sectional study used baseline data from a longitudinal, observational study from 2020 to 2023, including up to 3 years of follow-up. Participants were enrolled from 3 Alzheimer Disease …

Multiancestry Analysis Of The Hla Locus In Alzheimer’S And Parkinson’S Diseases Uncovers A Shared Adaptive Immune Response Mediated By Hla-Drb1*04 Subtypes, Yann Le Guen, Guo Luo, Aditya Ambati, Vincent Damotte, Iris Jansen, Eric Yu, Aude Nicolas, Itziar De Rojas, Thiago Peixoto Leal, Akinori Miyashita, Céline Bellenguez, Michelle Mulan Lian, Kayenat Parveen, Takashi Morizono, Hyeonseul Park, Benjamin Grenier-Boley, Tatsuhiko Naito, Fahri Küçükali, Seth D Talyansky, Selina Maria Yogeshwar, Vicente Sempere, Wataru Satake, Victoria Alvarez, Beatrice Arosio, Michael E Belloy, Luisa Benussi, Anne Boland, Barbara Borroni, María J Bullido, Paolo Caffarra, Jordi Clarimon, Antonio Daniele, Daniel Darling, Stéphanie Debette, Jean-François Deleuze, Martin Dichgans, Carole Dufouil, Emmanuel During, Emrah Düzel, Daniela Galimberti, Guillermo Garcia-Ribas, José María García-Alberca, Pablo García-González, Vilmantas Giedraitis, Oliver Goldhardt, Caroline Graff, Edna Grünblatt, Olivier Hanon, Lucrezia Hausner, Stefanie Heilmann-Heimbach, Henne Holstege, Jakub Hort, Yoo Jin Jung, Deckert Jürgen, Silke Kern, Teemu Kuulasmaa, Kun Ho Lee, Ling Lin, Carlo Masullo, Patrizia Mecocci, Shima Mehrabian, Alexandre De Mendonça, Mercè Boada, Pablo Mir, Susanne Moebus, Fermin Moreno, Benedetta Nacmias, Gael Nicolas, Shumpei Niida, Børge G Nordestgaard, Goran Papenberg, Janne Papma, Lucilla Parnetti, Florence Pasquier, Pau Pastor, Oliver Peters, Yolande A L Pijnenburg, Gerard Piñol-Ripoll, Julius Popp, Laura Molina Porcel, Raquel Puerta, Jordi Pérez-Tur, Innocenzo Rainero, Inez Ramakers, Luis M Real, Steffi Riedel-Heller, Eloy Rodriguez-Rodriguez, Owen A Ross, Luis Jose Royo, Dan Rujescu, Nikolaos Scarmeas, Philip Scheltens, Norbert Scherbaum, Anja Schneider, Davide Seripa, Ingmar Skoog, Vincenzo Solfrizzi, Gianfranco Spalletta, Alessio Squassina, John Van Swieten, Raquel Sánchez-Valle, Eng-King Tan, Thomas Tegos, Charlotte Teunissen, Jesper Qvist Thomassen, Lucio Tremolizzo, Martin Vyhnalek, Frans Verhey, Margda Waern, Jens Wiltfang, Jing Zhang, Eadb, Gr@Ace Study Group, Degesco Consortium, Demgene, Eadi, Gerad, Asian Parkinson’S Disease Genetics Consortium, Henrik Zetterberg, Kaj Blennow, Zihuai He, Julie Williams, Philippe Amouyel, Frank Jessen, Patrick G Kehoe, Ole A Andreassen, Cornelia Van Duin, Magda Tsolaki, Pascual Sánchez-Juan, Ruth Frikke-Schmidt, Kristel Sleegers, Tatsushi Toda, Anna Zettergren, Martin Ingelsson, Yukinori Okada, Giacomina Rossi, Mikko Hiltunen, Jungsoo Gim, Kouichi Ozaki, Rebecca Sims, Jia Nee Foo, Wiesje Van Der Flier, Takeshi Ikeuchi, Alfredo Ramirez, Ignacio Mata, Agustín Ruiz, Ziv Gan-Or, Jean-Charles Lambert, Michael D Greicius, Emmanuel Mignot

Faculty, Staff and Students Publications

Across multiancestry groups, we analyzed Human Leukocyte Antigen (HLA) associations in over 176,000 individuals with Parkinson’s disease (PD) and Alzheimer’s disease (AD) versus controls. We demonstrate that the two diseases share the same protective association at the HLA locus. HLA-specific fine-mapping showed that hierarchical protective effects of HLA-DRB1*04 subtypes best accounted for the association, strongest with HLA-DRB1*04:04 and HLA-DRB1*04:07, and intermediary with HLA-DRB1*04:01 and HLA-DRB1*04:03. The same signal was associated with decreased neurofibrillary tangles in postmortem brains and was associated with reduced tau levels in cerebrospinal fluid and to a lower extent with increased Aβ42. …

The Impact Of Covid-19 On Carotid-Femoral Pulse Wave Velocity: A Systematic Review And Meta-Analysis, Iwona Jannasz, Michal Pruc, Mansur Rahnama-Hezavah, Tomasz Targowski, Robert Olszewski, Stepan Feduniw, Karolina Petryka, Lukasz Szarpak

Faculty, Staff and Students Publications

COVID-19 is a complex multisystemic disease that can result in long-term complications and, in severe cases, death. This study investigated the effect of COVID-19 on carotid–femoral pulse wave velocity (cfPWV) as a measurement to evaluate its impact on arterial stiffness and might help predict COVID-19-related cardiovascular (CV) complications. PubMed, Web of Science, Embase, and the Cochrane Library were searched for relevant studies, and meta-analysis was performed. The study protocol was registered in PROSPERO (nr. CRD42023434326). The Newcastle–Ottawa Quality Scale was used to evaluate the quality of the included studies. Nine studies reported cfPWV among COVID-19 patients and control groups. The …