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Retirement Planning: A Moderated Mediation Model Of Cognitive Beliefs, Retirement Planning Attitude, And Money Availability, Afm Jalal Ahamed, Yam B. Limbu Jun 2024

Retirement Planning: A Moderated Mediation Model Of Cognitive Beliefs, Retirement Planning Attitude, And Money Availability, Afm Jalal Ahamed, Yam B. Limbu

Department of Marketing Faculty Scholarship and Creative Works

Retirement planning has been extensively studied in developed countries; however, it has received scant scholarly attention in developing nations. This study examines the role of cognitive factors associated with retirement planning intentions in the context of a developing country, focusing on financial risk tolerance and self-efficacy within the cognitive appraisal theory framework, considering the mediating role of retirement planning attitudes and the moderating impact of financial resource availability. Data collected from surveys of 301 adults in Dhaka, Bangladesh were analyzed using a Partial Least Squares Structural Equation Modeling (PLS-SEM) approach. Findings revealed that retirement planning attitudes mediate the relationship between …


Differences In Aerobic Capacity And Running Speed Across Various Somatotype Structures And Body Fat Compositions Among Professional Football Athletes In Indonesia, Dhoni Akbar Ghozali, Muhammad Syauqi Ridhallah, Syania Shabrina, Ahmad Isnaini Shidqi Nurhani, Yunia Hastami, Dwi Rahayu, Lukman Aryoseto, Selfi Handayani, Siti Munawaroh, Nanang Wiyono, Agus Sugeng Riyanto, Enrico Ananda Budiono, Annisa Aghnia Rahma, Muhana Fawwazy Ilyas Jun 2024

Differences In Aerobic Capacity And Running Speed Across Various Somatotype Structures And Body Fat Compositions Among Professional Football Athletes In Indonesia, Dhoni Akbar Ghozali, Muhammad Syauqi Ridhallah, Syania Shabrina, Ahmad Isnaini Shidqi Nurhani, Yunia Hastami, Dwi Rahayu, Lukman Aryoseto, Selfi Handayani, Siti Munawaroh, Nanang Wiyono, Agus Sugeng Riyanto, Enrico Ananda Budiono, Annisa Aghnia Rahma, Muhana Fawwazy Ilyas

Folia Medica Indonesiana

Highlights: 1. This study emphasizes the significance of understanding professional football players' various somatotype structures and body fat compositions as an important contribution to the area of sports science. This study lays the groundwork for future research to better understand the intricate interactions between somatotype structures, body composition, and athletic performance. 2. Since a one-size-fits-all approach may not be successful, this study advocates for tailored evaluations of training regimens to cater to athletes' unique requirements and skills, which may lead to higher overall performance. Abstract This study investigated the effects of somatotype structures and body fat composition on professional football …


A Comprehensive Examination Of Age-Related Lower Limb Muscle Function Asymmetries Across A Variety Of Muscle Action Types, Kylee L. Heap-Eldridge, Brennan J. Thompson, Cody Fisher, Talin J. Louder, Jon Carey Jun 2024

A Comprehensive Examination Of Age-Related Lower Limb Muscle Function Asymmetries Across A Variety Of Muscle Action Types, Kylee L. Heap-Eldridge, Brennan J. Thompson, Cody Fisher, Talin J. Louder, Jon Carey

Kinesiology and Health Science Faculty Publications

Previous research has found that lower limb muscle asymmetries increase with age and are linked to fall and injury risks. However, past studies lack a wide variety of muscle function modes and measures as well as comparison to a comparable younger age group. The purpose of this study was to examine age-related lower limb muscle function asymmetries across a variety of muscle action types and velocities in young and old adults. Lower limb balance, strength, power, and velocity were evaluated with concentric, isometric, isotonic, and eccentric muscle actions during a single-leg stance test and on single- and multi-joint dynamometers in …


Determining The Optimal Dosage Of Dexmedetomidine For Smooth Emergence In Older Patients Undergoing Spinal Surgery: A Study Of 44 Cases, Hyoeun Ahn, Yun Jeong Chae, Gyu Bin Choi, Min Gyu Lee, Ji Young Yoo Jun 2024

Determining The Optimal Dosage Of Dexmedetomidine For Smooth Emergence In Older Patients Undergoing Spinal Surgery: A Study Of 44 Cases, Hyoeun Ahn, Yun Jeong Chae, Gyu Bin Choi, Min Gyu Lee, Ji Young Yoo

Faculty, Staff and Student Publications

BACKGROUND Emergence agitation, or delirium, occurs during early recovery from general anesthesia and involves disorientation, excitation, and uncontrolled physical movements. Dexmedetomidine is an alpha agonist that has sedative, anxiolytic, analgesic, and sympatholytic activities and is used as a continuous infusion to prevent emergence agitation. This study aimed to evaluate patients aged 65 years and older undergoing general anesthesia to determine the 90% effective dose (ED90) of dexmedetomidine continuous intraoperative infusion to prevent emergence agitation. MATERIAL AND METHODS We enrolled 44 patients aged 65 years and older undergoing spinal surgery under general anesthesia. Dexmedetomidine administration commenced 30 minutes before surgery completion, …


Deserts Still Need Water: Using Adr Processes To Support Rural Residents And Counter The Challenges Stemming From The Shortage Of Lawyers In The “Great American Legal Desert”, Whitney Heuermann Jun 2024

Deserts Still Need Water: Using Adr Processes To Support Rural Residents And Counter The Challenges Stemming From The Shortage Of Lawyers In The “Great American Legal Desert”, Whitney Heuermann

Pepperdine Dispute Resolution Law Journal

Researchers dub rural America the “Great American Legal Desert,” deriving its nickname from the fact that roughly 20% of the nation's population lives in rural America while only 2% of small law practices are located in rural areas. This comment proposes that an increase in alternative dispute resolution (ADR) programming and usage serves as a viable avenue to alleviate the lawyer shortage’s harmful effects in rural America. This note begins by generally identifying ADR’s pros, such as cost, privacy, and community preservation, and then correlating these advantages to various aspects of rural America. ADR programming in Kentucky, Idaho, and Kansas …


Ethical, Legal, And Policy Challenges In Field-Based Neuroimaging Research Using Emerging Portable Mri Technologies: Guidance For Investigators And For Oversight, Francis X. Shen, Susan M. Wolf, Frances P. Lawrenz, Donnella S. Comeau, Kafui Dzirasa, Barbara J. Evans, Damien A. Fair, Martha J. Farah, Duke Han, Judy Illes, Jonathan D. Jackson, Eran Klein, Karen S. Rommelfanger, Matthew S. Rosen, Efraín Torres, Paul Tuite, J. Thomas Vaughan, Michael Garwood Jun 2024

Ethical, Legal, And Policy Challenges In Field-Based Neuroimaging Research Using Emerging Portable Mri Technologies: Guidance For Investigators And For Oversight, Francis X. Shen, Susan M. Wolf, Frances P. Lawrenz, Donnella S. Comeau, Kafui Dzirasa, Barbara J. Evans, Damien A. Fair, Martha J. Farah, Duke Han, Judy Illes, Jonathan D. Jackson, Eran Klein, Karen S. Rommelfanger, Matthew S. Rosen, Efraín Torres, Paul Tuite, J. Thomas Vaughan, Michael Garwood

UF Law Faculty Publications

Researchers are rapidly developing and deploying highly portable MRI technology to conduct field-based research. The new technology will widen access to include new investigators in remote and unconventional settings and will facilitate greater inclusion of rural, economically disadvantaged, and historically underrepresented populations. To address the ethical, legal, and societal issues raised by highly accessible and portable MRI, an interdisciplinary Working Group (WG) engaged in a multi-year structured process of analysis and consensus building, informed by empirical research on the perspectives of experts and the general public. This article presents the WG’s consensus recommendations. These recommendations address technology quality control, design …


Prevalence And Correlates Of Antipsychotic Medication Use In Oregon Assisted Living, Sarah Dys, Ozcan Tunalilar, Paula Carder Jun 2024

Prevalence And Correlates Of Antipsychotic Medication Use In Oregon Assisted Living, Sarah Dys, Ozcan Tunalilar, Paula Carder

Institute on Aging Publications

Objective

Investigate how assisted living and residential care (AL/RC) and memory care (MC) contexts are associated with the 90-day prevalence of antipsychotic medication use (APU), considered a quality measure in long-term care.

Design

All licensed AL/RC settings in Oregon received an annual mailed questionnaire to provide aggregate resident demographics, health acuity, health service use, payment type, and organizational policies. Organizational measures were collected from state websites.

Methods

Random intercepts regression models were estimated to assess organizational and resident population characteristics associated with 90-day APU prevalence over 3 study waves (2017-2019).

Setting and Participants

We examine 932 observations in 463 AL/RC …


Vol.51 N.46 June 6th 2024, Voice Media Ventures Jun 2024

Vol.51 N.46 June 6th 2024, Voice Media Ventures

Black Voice News

No abstract provided.


Vol.51 N.46 June 6, 2024, Voice Media Ventures Jun 2024

Vol.51 N.46 June 6, 2024, Voice Media Ventures

Black Voice News

No abstract provided.


Using Discrete-Event Simulation To Balance Staff Allocation And Patient Flow Between Clinic And Surgery In A Pediatric Hospital Setting, John Forbus Jun 2024

Using Discrete-Event Simulation To Balance Staff Allocation And Patient Flow Between Clinic And Surgery In A Pediatric Hospital Setting, John Forbus

Theses and Dissertations

We review the problem of a system-level balanced scheduling scenario. A hospital clinic has a queue for patients needing care. After being seen in clinic, many require follow-up surgery, for which they also wait in a queue. The rate-limiting factor is physician availability for both clinic visits and surgical cases. Much existing work has been done to optimize clinic appointments, as well as to optimize surgical appointments. This novel approach models the entire patient journey at the system level, through both clinic and surgery, to optimize the total patient experience. A discrete-event simulation model of the system is built based …


Caring Behaviors Of Nursing Students And Their Attitudes Toward Older Adults, Jacquelyn D. Lambert-Davis Jun 2024

Caring Behaviors Of Nursing Students And Their Attitudes Toward Older Adults, Jacquelyn D. Lambert-Davis

Dissertations

Caring is an emotion. It is a feeling of compassion and an understanding of the difficulties of others. Research indicates that caring behaviors and attitudes are an important part of the knowledge base for nursing students. Caring behaviors and attitudes are an important part of the knowledge base for nursing students in order to provide competent care for older adults. This descriptive cross-sectional study reports findings of caring attitudes and behaviors of nursing students using the Caring Dimensions Inventory (CDI). The purpose of this study was to examine the self reported attitudes and caring behaviors of nursing students toward older …


Midweek Memo, Georgia Southern University Jun 2024

Midweek Memo, Georgia Southern University

Midweek Memo

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Episodic Memory Influences On Decision-Making: An Fmri Investigation Of Young And Older Adult Populations, Julie Van Jun 2024

Episodic Memory Influences On Decision-Making: An Fmri Investigation Of Young And Older Adult Populations, Julie Van

Theses and Dissertations

Episodic memory involves the ability to remember specific events and personal experiences. It shares computational and neural resources with episodic future thinking, or the ability to simulate future episodes in anticipation of situations that have not yet occurred. Activity in the frontal lobe has been associated with episodic memory formation, as functional connectivity between the medial temporal lobe (MTL) and prefrontal cortex (PFC) has been associated with the organization and manipulation of information when forming memories. At its core, episodic memory extends to several other functional domains by recombining past information to construct future scenarios, facilitating an aspect of "mental …


Effectiveness Of A Health Literacy Enhancement Program For Older Adults In Northern Thailand, Kasama Pooseesod, Sayambhu Saita, Supa Vittaporn, Jirapat Longkul, Ruchirada Changkwanyeun, Nattagorn Choochouy, Chaiwat Phadermrod, Patsiri Srivieng, Supang Wattanasoei Jun 2024

Effectiveness Of A Health Literacy Enhancement Program For Older Adults In Northern Thailand, Kasama Pooseesod, Sayambhu Saita, Supa Vittaporn, Jirapat Longkul, Ruchirada Changkwanyeun, Nattagorn Choochouy, Chaiwat Phadermrod, Patsiri Srivieng, Supang Wattanasoei

Journal of Health Research

Background: The aim of this study was to evaluate the effectiveness of a health literacy enhancement program on the health literacy and 3E2S health behaviors (eating, emotion, exercise, stop smoking and stop drinking). We also explored the facilitators and barriers for older adults in developing health literacy and self-care behaviors.

Methods: The study utilized a mixed methods sequential explanatory design. The participants (n = 60) were people aged 60 years and older living in the Hang Chat District, Lampang Province, which located in northern Thailand. The data were collected using pre- and post-questionnaires and an in-depth interview. Quantitative …


Faculty Senate Monthly Packet June 2024, Portland State University Faculty Senate Jun 2024

Faculty Senate Monthly Packet June 2024, Portland State University Faculty Senate

Faculty Senate Monthly Packets

The June 3, 2024 monthly packet includes the June agenda, appendices, and the Faculty Senate minutes and attachments from the meeting held June 3, 2024.


Postural Control In Adults With Age-Related Hearing Loss, Elizabeth Tobener Jun 2024

Postural Control In Adults With Age-Related Hearing Loss, Elizabeth Tobener

Alternative Theses and Dissertations (AETDs)

The present study investigated postural control measures in adults with age-related hearing loss (ARHL). Individuals between the age of 50 and 70 were recruited (10 with normal hearing, 32 with ARHL) and evaluated using pure-tone audiometry, vestibular function assessments, and postural control measures. Results of this study revealed significant correlations between ARHL and cervical vestibular evoked myogenic potential (VEMPs) and ocular VEMPs. As ARHL increased, amplitude of cervical VEMPs and ocular VEMPs decreased. There were no significant correlations for ARHL and video head impulse test (vHIT) gain. Single leg stance with head tilt was significantly associated with ARHL. As ARHL …


Wofford Today Summer 2024, Wofford College. Office Of Marketing And Communications Jun 2024

Wofford Today Summer 2024, Wofford College. Office Of Marketing And Communications

Wofford Today

No abstract provided.


Cognitive Reserve, Cortisol, And Alzheimer's Disease Biomarkers: A Memory Clinic Study, Manasa Yerramalla, Alexander Darin-Mattsson, Chinedu Momoh, Jasper Holleman, Ingemar Kåreholt, Malin Aspö, Göran Hagman, Miia Kivipelto, Alina Solomon, Anna Marseglia Jun 2024

Cognitive Reserve, Cortisol, And Alzheimer's Disease Biomarkers: A Memory Clinic Study, Manasa Yerramalla, Alexander Darin-Mattsson, Chinedu Momoh, Jasper Holleman, Ingemar Kåreholt, Malin Aspö, Göran Hagman, Miia Kivipelto, Alina Solomon, Anna Marseglia

Brain and Mind Institute

INTRODUCTION Cognitive reserve might mitigate the risk of Alzheimer's dementia among memory clinic patients. No study has examined the potential modifying role of stress on this relation.

METHODS We examined cross-sectional associations of the cognitive reserve index (CRI; education, occupational complexity, physical and leisure activities, and social health) with cognitive performance and AD-related biomarkers among 113 memory clinic patients. The longitudinal association between CRI and cognition over a 3-year follow-up was assessed. We examined whether associations were influenced by perceived stress and five measures of diurnal salivary cortisol.

RESULTS Higher CRI scores were associated with better cognition. Adjusting for cortisol …


Effect Of Long-Term Caloric Restriction On Telomere Length In Healthy Adults: Calerie™ 2 Trial Analysis, Waylon J. Hastings, Qiaofeng Ye, Sarah E. Wolf, Calen P. Ryan, Sai Krupa Das, Kim M. Huffman, Michael S. Kobor, William E. Kraus, Julia L. Macisaac, Corby K. Martin, Susan B. Racette, Leanne M. Redman, Daniel W. Belsky, Idan Shalev Jun 2024

Effect Of Long-Term Caloric Restriction On Telomere Length In Healthy Adults: Calerie™ 2 Trial Analysis, Waylon J. Hastings, Qiaofeng Ye, Sarah E. Wolf, Calen P. Ryan, Sai Krupa Das, Kim M. Huffman, Michael S. Kobor, William E. Kraus, Julia L. Macisaac, Corby K. Martin, Susan B. Racette, Leanne M. Redman, Daniel W. Belsky, Idan Shalev

Clinical Research Faculty Publications

Caloric restriction (CR) modifies lifespan and aging biology in animal models. The Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy (CALERIE™) 2 trial tested translation of these findings to humans. CALERIE™ randomized healthy, nonobese men and premenopausal women (age 21–50y; BMI 22.0–27.9 kg/m2), to 25% CR or ad-libitum (AL) control (2:1) for 2 years. Prior analyses of CALERIE™ participants' blood chemistries, immunology, and epigenetic data suggest the 2-year CR intervention slowed biological aging. Here, we extend these analyses to test effects of CR on telomere length (TL) attrition. TL was quantified in blood samples collected at baseline, 12-, …


忘年交 / A Friendship That Transcends Age, Zichen Zhou Jun 2024

忘年交 / A Friendship That Transcends Age, Zichen Zhou

Masters Theses

In today’s swiftly aging society, China grapples with the challenge of elderly individuals gradually becoming disconnected from the social fabric, often leading to the phenomenon of empty-nesting, especially in China’s eastern urban areas. Understanding and addressing the needs of the elderly is crucial for designing environments, that give continued meaning to the lives of the elderly, and create connections with the rest of society. Further, the elderly are a resource for families, capable of providing childcare and even housing to younger generations, whether the younger generations want this help or not. In response to the challenge of keeping the elderly …


Impact Of Low-Load Resistance Exercise With And Without Blood Flow Restriction On Muscle Strength, Endurance, And Oxidative Capacity: A Pilot Study, Brett H. Davis, James E. Stampley, Joshua Granger, Matthew C. Scott, Timothy D. Allerton, Neil M. Johannsen, Guillaume Spielmann, Brian A. Irving Jun 2024

Impact Of Low-Load Resistance Exercise With And Without Blood Flow Restriction On Muscle Strength, Endurance, And Oxidative Capacity: A Pilot Study, Brett H. Davis, James E. Stampley, Joshua Granger, Matthew C. Scott, Timothy D. Allerton, Neil M. Johannsen, Guillaume Spielmann, Brian A. Irving

Clinical Research Faculty Publications

Low-load resistance exercise (LLRE) to failure can increase muscle mass, strength, endurance, and mitochondrial oxidative capacity (OXPHOS). However, the impact of adding blood flow restriction to low-load resistance exercise (LLBFR) when matched for volume on these outcomes is incompletely understood. This pilot study examined the impact of 6 weeks of single-legged LLBFR and volume-matched LLRE on thigh bone-free lean mass, strength, endurance, and mitochondrial OXPHOS. Twenty (12 males and 8 females) untrained young adults (mean ± SD; 21 ± 2 years, 168 ± 11 cm, 68 ± 12 kg) completed 6 weeks of either single-legged LLBFR or volume-matched LLRE. Participants …


Recognizing Elder Abuse In Mongolia: Experiences Of Family Physicians, Ariunsanaa Bagaajav Jun 2024

Recognizing Elder Abuse In Mongolia: Experiences Of Family Physicians, Ariunsanaa Bagaajav

Dissertations, Theses, and Capstone Projects

Elder abuse is a globally recognized social problem with serious consequences. The most recent meta-analysis estimates the prevalence of elder abuse at 17%. Studies conducted in Asian countries suggest prevalence rates higher than the global average. Social stressors including alcoholism, unemployment, and poverty related to economic transitions, many of which apply in Mongolia, are associated with elder abuse. International studies have found that health care providers play critical roles in detecting cases of elder abuse. Due to universal access to primary care in Mongolia, family physicians are uniquely positioned to interact with potential victims of elder abuse. However, the extent …


Enhancing Foot Care Education And Support Strategies In Adults With Type 2 Diabetes, Hsiao-Hui Ju, Madelene Ottosen, Jeffery Alford, Jed Jularbal, Constance Johnson Jun 2024

Enhancing Foot Care Education And Support Strategies In Adults With Type 2 Diabetes, Hsiao-Hui Ju, Madelene Ottosen, Jeffery Alford, Jed Jularbal, Constance Johnson

Faculty, Staff and Student Publications

BACKGROUND: People with diabetes are susceptible to serious and disabling foot complications, which increase their morbidity and mortality rates. Examining the perspectives of people with diabetes on their foot care routines could help elucidate their beliefs and offer practical ways to prevent foot problems.

PURPOSE: We explored the perspectives of adults with diabetes on their foot care practices to identify and enhance foot care education and support strategies.

METHODOLOGY: Using the Zoom platform, 29 adults with diabetes completed a 3-month telehealth educational program, during which interviews were conducted. This article reports the results of thematic content analysis of the qualitative …


Life-Space Mobility, Transportation, And The Companionship Network Of Members Of A Hispanic Senior Center, Rebecca L Mauldin, Rupal Parekh, John P Connolly, Stephen P Mattingly, Aiman Mushtaq, Kayo Fujimoto Jun 2024

Life-Space Mobility, Transportation, And The Companionship Network Of Members Of A Hispanic Senior Center, Rebecca L Mauldin, Rupal Parekh, John P Connolly, Stephen P Mattingly, Aiman Mushtaq, Kayo Fujimoto

Faculty, Staff and Student Publications

Objectives: Companions (i.e., friends who spend time together) are important for the well-being of older adults. Senior centers in the United States are places for older adults to participate in group activities and form and maintain companionships. However, differences in mobility and transportation may affect the ability of older adults to leverage senior center activities into actual companionships.

Methods: This social network analysis was conducted to characterize the companionship network among members of a senior center in relation to their life-space mobility and transportation resources. An exponential random graph model was estimated to identify mobility- and transportation-related correlates of the …


Time-To-Event Genome-Wide Association Study For Incident Cardiovascular Disease In People With Type 2 Diabetes, Soo Heon Kwak, Ryan B Hernandez-Cancela, Daniel A Dicorpo, David E Condon, Jordi Merino, Peitao Wu, Jennifer A Brody, Jie Yao, Xiuqing Guo, Fariba Ahmadizar, Mariah Meyer, Murat Sincan, Josep M Mercader, Sujin Lee, Jeffrey Haessler, Ha My T Vy, Zhaotong Lin, Nicole D Armstrong, Shaopeng Gu, Noah L Tsao, Leslie A Lange, Ningyuan Wang, Kerri L Wiggins, Stella Trompet, Simin Liu, Ruth J F Loos, Renae Judy, Philip H Schroeder, Natalie R Hasbani, Maxime M Bos, Alanna C Morrison, Rebecca D Jackson, Alexander P Reiner, Joann E Manson, Ninad S Chaudhary, Lynn K Carmichael, Yii-Der Ida Chen, Kent D Taylor, Mohsen Ghanbari, Joyce Van Meurs, Achilleas N Pitsillides, Bruce M Psaty, Raymond Noordam, Ron Do, Kyong Soo Park, J Wouter Jukema, Maryam Kavousi, Adolfo Correa, Stephen S Rich, Scott M Damrauer, Catherine Hajek, Nam H Cho, Marguerite R Irvin, James S Pankow, Girish N Nadkarni, Robert Sladek, Mark O Goodarzi, Jose C Florez, Daniel I Chasman, Susan R Heckbert, Charles Kooperberg, Josée Dupuis, Rajeev Malhotra, Paul S De Vries, Ching-Ti Liu, Jerome I Rotter, James B Meigs Jun 2024

Time-To-Event Genome-Wide Association Study For Incident Cardiovascular Disease In People With Type 2 Diabetes, Soo Heon Kwak, Ryan B Hernandez-Cancela, Daniel A Dicorpo, David E Condon, Jordi Merino, Peitao Wu, Jennifer A Brody, Jie Yao, Xiuqing Guo, Fariba Ahmadizar, Mariah Meyer, Murat Sincan, Josep M Mercader, Sujin Lee, Jeffrey Haessler, Ha My T Vy, Zhaotong Lin, Nicole D Armstrong, Shaopeng Gu, Noah L Tsao, Leslie A Lange, Ningyuan Wang, Kerri L Wiggins, Stella Trompet, Simin Liu, Ruth J F Loos, Renae Judy, Philip H Schroeder, Natalie R Hasbani, Maxime M Bos, Alanna C Morrison, Rebecca D Jackson, Alexander P Reiner, Joann E Manson, Ninad S Chaudhary, Lynn K Carmichael, Yii-Der Ida Chen, Kent D Taylor, Mohsen Ghanbari, Joyce Van Meurs, Achilleas N Pitsillides, Bruce M Psaty, Raymond Noordam, Ron Do, Kyong Soo Park, J Wouter Jukema, Maryam Kavousi, Adolfo Correa, Stephen S Rich, Scott M Damrauer, Catherine Hajek, Nam H Cho, Marguerite R Irvin, James S Pankow, Girish N Nadkarni, Robert Sladek, Mark O Goodarzi, Jose C Florez, Daniel I Chasman, Susan R Heckbert, Charles Kooperberg, Josée Dupuis, Rajeev Malhotra, Paul S De Vries, Ching-Ti Liu, Jerome I Rotter, James B Meigs

Faculty, Staff and Student Publications

Objective: To identify genetic risk factors for incident cardiovascular disease (CVD) among people with type 2 diabetes (T2D).

Research design and methods: We conducted a multiancestry time-to-event genome-wide association study for incident CVD among people with T2D. We also tested 204 known coronary artery disease (CAD) variants for association with incident CVD.

Results: Among 49,230 participants with T2D, 8,956 had incident CVD events (event rate 18.2%). We identified three novel genetic loci for incident CVD: rs147138607 (near CACNA1E/ZNF648, hazard ratio [HR] 1.23, P = 3.6 × 10-9), rs77142250 (near HS3ST1, HR 1.89, P = 9.9 × 10-9), and rs335407 (near …


Bidirectional Two-Sample Mendelian Randomization Study Of Immunoglobulin G N-Glycosylation And Senescence-Associated Secretory Phenotype, Haotian Wang, Di Liu, Xiaoni Meng, Wenxin Sun, Cancan Li, Huimin Lu, Deqiang Zheng, Lijuan Wu, Shengzhi Sun, Youxin Wang Jun 2024

Bidirectional Two-Sample Mendelian Randomization Study Of Immunoglobulin G N-Glycosylation And Senescence-Associated Secretory Phenotype, Haotian Wang, Di Liu, Xiaoni Meng, Wenxin Sun, Cancan Li, Huimin Lu, Deqiang Zheng, Lijuan Wu, Shengzhi Sun, Youxin Wang

Research outputs 2022 to 2026

Observational studies revealed changes in Immunoglobulin G (IgG) N-glycosylation during the aging process. However, it lacks causal insights and remains unclear in which direction causal relationships exist. The two-sample bidirectional Mendelian randomization (MR) design was adopted to explore causal associations between IgG N-glycans and the senescence-associated secretory phenotype (SASP). Inverse variance weighted (IVW) and Wald ratio methods were used as the main analyses, supplemented by sensitivity analyses. Forward MR analyses revealed causal associations between the glycan peak (GP) and SASP, including GP6 (odds ratio [OR] = 0.428, 95% confidence interval [CI] = 0.189–0.969) and GP17 (OR = 0.709, 95%CI = …


Protocol: Factors Influencing The Implementation Of Non-Pharmacological Interventions For Behaviours And Psychological Symptoms Of Dementia In Residential Aged Care Homes: A Systematic Review And Qualitative Evidence Synthesis, Hunduma D. Ayeno, Gizat M. M. Kassie, Mustafa Atee, Tuan Nguyen Jun 2024

Protocol: Factors Influencing The Implementation Of Non-Pharmacological Interventions For Behaviours And Psychological Symptoms Of Dementia In Residential Aged Care Homes: A Systematic Review And Qualitative Evidence Synthesis, Hunduma D. Ayeno, Gizat M. M. Kassie, Mustafa Atee, Tuan Nguyen

Research outputs 2022 to 2026

This is a protocol for a Cochrane Review. The objectives are as follows. This paper aims to describe a protocol for a systematic review that will synthesise the qualitative evidence regarding factors influencing the implementation of non-pharmacological interventions (NPIs) for behavioural and psychological symptoms of dementia (BPSD) management in residential aged care homes (RACHs). The planned systematic review aims to answer the research question: ‘What are the factors influencing the implementation of NPIs in the management of BPSD at RACHs?’. Additionally, the planned systematic review also aims to generate recommendations to guide stakeholders (e.g., clinicians and aged care staff) and …


The Effects Of Occupational Disruption During Covid-19 Lockdowns On Health: A Cross-Sectional Study, Bernard Austin Kigunda Muriithi, R. Curtis Bay Jun 2024

The Effects Of Occupational Disruption During Covid-19 Lockdowns On Health: A Cross-Sectional Study, Bernard Austin Kigunda Muriithi, R. Curtis Bay

Communication Disorders and Occupational Therapy Faculty Publications and Presentations

The disruption in daily activity performance during COVID-19 lockdowns is widely understood to have impacted health, but a better understanding of how restricted performance of specific activities are associated with health is needed. This cross-sectional study answers the following question: How were changes in the performance of 16 daily activities associated with health during COVID-19 lockdowns? A total of 116 participants completed an online survey rating their health before and during COVID-19 lockdowns and comparing their recollection of the performance of 16 activities before COVID-19 with their performance during lockdowns. Multiple stepwise linear regression analysis was used to estimate the …


Effect Of Robotic Training On The Mobility Of Children With Cerebral Palsy: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials, Fu-An Yang, Ya-Chu Shih, Li-Fong Lin, Chih-Wei Peng, Chien-Hung Lai, Tsan-Hon Liou, Reuben Escorpizo, Hung-Chou Chen Jun 2024

Effect Of Robotic Training On The Mobility Of Children With Cerebral Palsy: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials, Fu-An Yang, Ya-Chu Shih, Li-Fong Lin, Chih-Wei Peng, Chien-Hung Lai, Tsan-Hon Liou, Reuben Escorpizo, Hung-Chou Chen

Rehabilitation Practice and Science

In this study, we conducted a systematic review and meta-analysis to investigate the effect of robotic training on the mobility of children with cerebral palsy. The PubMed, Cochrane Library, PEDro, and Embase databases were searched for relevant studies from their inception to June 17, 2023. We selected studies that (1) were randomized controlled trials (RCTs), (2) included patients with cerebral palsy aged years, (3) compared robotic training with conventional rehabilitation alone, and (4) reported mobility outcomes. Continuous variables are expressed as standardized mean differences (SMDs) with 95% confidence intervals (CIs). The analysis was performed using RevMan 5.4 software. We included …


The Association Of Nursing Homes' Organizational Context With Care Aide Empowerment: A Cross-Sectional Study, Alba Iaconi, Matthias Hoben, Whitney Berta Phd, Yinfei Duan, Peter G Norton, Yuting Song, Stephanie A Chamberlain, Anna Beeber, Ruth A Anderson, Holly J Lanham, Janelle Perez, Jing Wang, Katharina Choroschun, Shovana Shrestha, Greta Cummings, Carole A Estabrooks Jun 2024

The Association Of Nursing Homes' Organizational Context With Care Aide Empowerment: A Cross-Sectional Study, Alba Iaconi, Matthias Hoben, Whitney Berta Phd, Yinfei Duan, Peter G Norton, Yuting Song, Stephanie A Chamberlain, Anna Beeber, Ruth A Anderson, Holly J Lanham, Janelle Perez, Jing Wang, Katharina Choroschun, Shovana Shrestha, Greta Cummings, Carole A Estabrooks

Faculty, Staff and Student Publications

Background and objectives: Organizational context is thought to influence whether care aides feel empowered, but we lack empirical evidence in the nursing home sector. Our objective was to examine the association of features of nursing homes' unit organizational context with care aides' psychological empowerment.

Research design and methods: This cross-sectional study analyzed survey data from 3765 care aides in 91 Western Canadian nursing homes. Random-intercept mixed-effects regressions were used to examine the associations between nursing home unit organizational context and care aides' psychological empowerment, controlling for care aide, care unit, and nursing home covariates.

Results: Organizational (IVs) culture, social capital, …