Digital Commons Network^™

Master Protocol Design With Hybrid Control For Efficient Early-Phase Trial Consolidation, Alexander M Kaizer, Xiaojiang Zhan, Eric Baron, Rui Sammi Tang, David S Hong, Brian P Hobbs

Faculty, Staff and Student Publications

Purpose: Master protocols represent transformations, enabling multiple therapies or diseases under a single protocol. These designs streamline therapeutic development by reducing redundancies. Suited for evolving fields such as oncology and global emergencies such as the COVID-19 pandemic, master protocols have been exemplified by studies such as RECOVERY, Solidarity, and I-SPY 2, which accelerated effective treatment identification (with I-SPY 2 focused on molecular subtypes). Recent oncology examples, such as MORPHEUS, evaluate immunotherapy combinations with shared controls. Despite advantages, their application in early-phase oncology remains underutilized amid growing regulatory emphasis on randomization for robust evidence.

Methods: US Food and Drug Administration (FDA) …

Funds Of Knowledge And The Transition To School: A Scoping Review, Amelia Ruscoe, Leanne Lavina, Lennie Barblett, Fiona Boylan

Research outputs 2022 to 2026

Children's funds of knowledge (FoK) were recognised in the initial iteration of the Australian Early Years Learning Framework (EYLF) in 2009, the mandated framework for educator decision-making, and their significance was further emphasised in EYLF 2.0 in 2022. However, a unified understanding of children as knowledgeable individuals and how to effectively incorporate their diverse knowledges into early childhood education is still evolving. Recent evidence highlights the link between engaging with children's FoK and supporting successful transitions to formal schooling. Given that childhood is experienced differently across cultures and contexts, achieving consensus on the nature and value of FoK remains a …

Product, Process, And Behavior Influences On Value Retention Processes: Toward A Circular Economy In Consumer Electronics, Kyle Parnell

Theses

Consumer electronic products (CEP) manufacturing and retail contribute markedly to global industrial activity; worldwide estimates suggest revenue growth from $1 trillion in 2020 to $1.5 trillion by 2026. Consequently, the production, distribution, use, and end-of-life (EOL) disposition of these products are responsible for considerable social and environmental impacts, including 35 million metric tonnes of waste to landfill per year, 793 million metric tonnes (MMT)—and growing—of carbon dioxide-equivalent (CO2e) greenhouse gas (GHG) emissions per year, and innumerable adverse effects on human health and development. Driving these impacts are the inherent characteristics of CEPs themselves, which increasingly require critical materials in design, …

Anticolonialism And Qualitative Methods For Culture-Centered Interventions, Mohan Jyoti Dutta, Ambar Basu, Satveer Kaur-Gill, Debalina Dutta, Mahuya Pal, Iccha Basnyat, Selina Metuamate, Venessa Pokaia, Phoebe Elers, Indranil Mandal, Rabindranath Mandi, Pankaj Baskey, Devalina Mookerjee, Shaunak Sastry, Jaime Robb, Andrew Carter

Faculty Research, Scholarly, and Creative Activity

In this essay, we a collective of Indigenous, Black, and migrant Global South scholars engaged in experiments with the culture-centered approach (CCA) draw on our lived experiences amidst struggles against land grab, neoliberal extractivism, and capitalist exploitation to outline a framework for qualitative methods as anticolonial politics. We begin by exploring the interplays of colonialism, imperialism, and racial capitalism that have shaped the origins and uses of qualitative methods toward serving extractive agendas of global capital. This critique serves as the basis for outlining the key principles of the CCA, turning to voice, storytelling, and embodied action as the basis …

Implementation Outcomes Of A Patient Decision-Aid In A Diverse Population With Systemic Lupus Erythematosus In 15 Us Rheumatology Clinics, Jasvinder A Singh, Larry R Hearld, Seth Eisen, W Winn Chatham, Sonali Narain, Narender Annapureddy, Diane L Kamen, Kimberly Trotter, Vikas Majithia, Cathy Lee Ching, Zineb Aouhab, Swamy Venuturupalli, Daniel J Wallace, Rosalind Ramsey-Goldman, Alfred Kim, Maureen Mcmahon, S Sam Lim, Kalpana Bhairavarasu, Alexa Meara, Kenneth Kalunian, T Mark Beasley

Faculty, Staff and Students Publications

Objective: The objective of this study was to examine the clinical outcomes during the implementation of a self-administered patient decision-aid (PtDA) for lupus.

Methods: We provided an effective computerized lupus PtDA in 15 rheumatology outpatient clinics 2019-2024 (including the COVID pandemic). We undertook Organizational Readiness to Implement Change Surveys (ORICs) and Team Learning and Psychological Safety Surveys (TLPSSs) at baseline. The primary study outcome objective measure, percent penetration/reach, was defined as the number of patients who viewed the lupus PtDA at the end of the study, divided by the total number of eligible patients (times 100). We used validated clinical …

State Of The Climate In 2024: The Arctic, R. L. Thoman, T. A. Moon, M. L. Druckenmiller, Thomas G. Askjaer, Thomas J. Ballinger, Uma S. Bhatt, Logan T. Berner, Germar H. Bernhard, Siiri Bigalke, Jarle W. Bjerke, Multiple Additional Authors

Geography Faculty Publications and Presentations

The Arctic environment in 2024 continued on a trajectory that has put it in a state far different from that of the twentieth century. Ongoing accumulation of greenhouse gases in the atmosphere continues to quickly warm the Arctic, resulting in rapid changes in the cryosphere that are driving cascading impacts to climate, ecological, and societal systems.

A New Approach To Probabilistic County Population Forecasting With An Example Application To West Texas, David Swanson, Jeff Tayman, Mike Cline

Publications, Reports and Presentations

This paper shows how measures of uncertainty can be applied to existing subnational population forecasts using the 107 counties that make up West Texas as a case study. The measures of forecast uncertainty are relatively easy to calculate and meet several important criteria routinely applied by state and local demographers. We also report the results of two independent comparisons supporting the argument that our approach is valid. The paper concludes it is well-suited for developing probabilistic population forecasts in the United States and elsewhere.

Sabin Cdc Affordable Infill Initiative, Andrew Lindstrom, Casey Dobbert, Josh Miller, Laura Fleming, Menodora Roos-Lemaster, Nick Flowers

Master of Urban and Regional Planning Workshop Projects

Grounded Growth Planning Cooperative partnered with Sabin Community Development Corporation (CDC), a non-profit affordable housing developer in North/Northeast Portland. The project goal was to examine 11 sites in their Scattered Sites Portfolio for the possibility of infill development to increase the portfolio’s financial performance and to provide additional housing to individuals with intellectual and developmental disabilities (IDD). Accessory Dwelling Units (ADUs) were the primary focus of the evaluation, as they can be constructed without modifying the existing housing and displacing existing tenants. The report identifies opportunities for Sabin CDC to take advantage of Portland zoning code changes that allow increased …

Implementation Outcomes Of A Patient Decision-Aid In A Diverse Population With Systemic Lupus Erythematosus In 15 Us Rheumatology Clinics, Jasvinder A Singh, Seth Eisen, Alfred Kim, Et Al.

2020-Current year OA Pubs

OBJECTIVE: The objective of this study was to examine the clinical outcomes during the implementation of a self-administered patient decision-aid (PtDA) for lupus.

METHODS: We provided an effective computerized lupus PtDA in 15 rheumatology outpatient clinics 2019-2024 (including the COVID pandemic). We undertook Organizational Readiness to Implement Change Surveys (ORICs) and Team Learning and Psychological Safety Surveys (TLPSSs) at baseline. The primary study outcome objective measure, percent penetration/reach, was defined as the number of patients who viewed the lupus PtDA at the end of the study, divided by the total number of eligible patients (times 100). We used validated clinical …

The Global Neurodegeneration Proteomics Consortium: Biomarker And Drug Target Discovery For Common Neurodegenerative Diseases And Aging, Farhad Imam, Muhammad Ali, Carlos Cruchaga, Chengran Yang, Et Al.

2020-Current year OA Pubs

More than 57 million people globally suffer from neurodegenerative diseases, a figure expected to double every 20 years. Despite this growing burden, there are currently no cures, and treatment options remain limited due to disease heterogeneity, prolonged preclinical and prodromal phases, poor understanding of disease mechanisms, and diagnostic challenges. Identifying novel biomarkers is crucial for improving early detection, prognosis, staging and subtyping of these conditions. High-dimensional molecular studies in biofluids ('omics') offer promise for scalable biomarker discovery, but challenges in assembling large, diverse datasets hinder progress. To address this, the Global Neurodegeneration Proteomics Consortium (GNPC)-a public-private partnership-established one of the …

Evaluating Methods Used To Quantify Racial Segregation, Sarah Cannon, Zarina Dhillon

Journal of Humanistic Mathematics

Racial segregation has long been a problem in communities across the United States. One approach to help understand such an important issue is to attempt to describe it quantitatively. Many metrics have been developed, all with various strengths and weaknesses, but none fully capture the nuances of this complicated issue. This work provides an overview of four of the mathematical approaches that have been developed to study segregation, explains how they function using small examples, and compares and contrasts their effectiveness in various situations. We then focus on segregation in Los Angeles (LA) County, including a detailed exploration of the …

Die Frage Der Entmythologisierung, Karl Jaspers, Rudolf Bultmann

Hannah Arendt Marginalia - All

München, R. Piper [c.1954]

Call #: BL51 .J35

Contains marginal lining

PDF Information: 44 pages – 3.4 MB

Aristotle; Fundamentals Of The History Of His Development., Werner Jaeger

Hannah Arendt Marginalia - All

London, Oxford University Press, 1962

Call #: B485 .J33 1962

Contains marginalia, underlining, marginal lining and endpaper notes.

PDF Information: 77 pages – 54 mb

Wandlungen In Den Grundlagen Der Naturwissenschaft, Werner Heisenberg

Hannah Arendt Marginalia - All

Zürich, S. Hirzel [©1948]

Call#: QC71 .H35

PDF Information: 21 pages – 20.7 MB

Interior Ecology Of Rural Houses In Çamlıhemşin, İrem Karadeniz Dündar, Tülay Zorlu

Interiority

Rural houses form a significant part of the rural architectural heritage, showing the region's lifestyle in their spatial organisation, types of spaces, and interior furnishings. This study examines the spatial characteristics of rural houses in Çamlıhemşin from the perspective of ecosophy, Guattari's (2005) approach of emphasising the reciprocity and intertwining of social, mental, and environmental ecologies. The impact of living culture on the spatial organisation and residential usage norms within the dwellings was evaluated and elucidated through an analysis of data gathered from on-site surveys, relevant literature, and archival scans. These data are interpreted according to the different characteristics and …

Family Homemaking Tactics In Tyneside Flats: Contemporary Interpretations Of Victorian Domestic Interior, Heba Sarhan, Rosie Parnell

Interiority

This study addresses the gap between knowledge of adaptable design and the socio-spatial practices within the interior spaces of contemporary domestic settings. The aim is to support the sustainability of residential environments by enhancing the adaptability of dwellings to changing and diverse home life needs. Consequently, this paper delves into design features that enhance the adaptability of interior domestic spaces, informed by everyday family homemaking processes. Through a case study of the Tyneside flat, this paper illustrates challenges of transitioning this flat from Victorian to contemporary family home. Drawing on data gathered using multimodal methods, the findings demonstrate homemaking tactics …

India As A Net Security Provider In South Asia: Challenges, Opportunities, And Geopolitical Dynamics, Ngo Tuan Thang, Tran My Hai Loc

Journal of Strategic and Global Studies

India’s emergence as a net security provider in South Asia is a significant development, driven by its strategic interests and the region's shifting geopolitical landscape. This paper explores the challenges, opportunities, and broader geopolitical dynamics that shape India’s security policies and initiatives in South Asia. Through qualitative research and the lens of structural realism, the study assesses India's efforts to maintain regional stability, counter terrorism, and address security threats in its immediate neighborhood, including Bangladesh, Nepal, Sri Lanka, Bhutan, and the Maldives. The analysis delves into the complexities posed by India’s traditional rivalries with Pakistan and China, highlighting how these …

Indonesia In Brics: A Realist Perspective, Brice Tseen Fu Lee, Kotchaphop Kornphetcharat, Juan Pablo Sims

Journal of Strategic and Global Studies

Indonesia’s 2025 accession to BRICS (Brazil, Russia, India, China, and South Africa) appears at odds with the country’s long-standing bebas-aktif (“free and active”) tradition of non-alignment. This article explains the move through a layered realist approach and a purely theoretical, deductive method. First, the study integrates structural, offensive, and neoclassical realism to clarify four key mechanisms external balancing, hedging, relative gains, and status-seeking. It then maps propositions about what BRICS can offer Indonesia and tests them against existing realist scholarship on middle powers and emerging-power clubs. Analysis shows that BRICS chiefly serves as an external-balancing instrument, reducing Jakarta’s reliance on …

Tackling Data Quality Challenges In Remote Sensing: Solutions For Reliable Urban Heat Island Analysis, Wei Xia, Aqil Tariq, Hesham El-Askary, Rana Waqar Aslam, Elgar Barboza, Dmitry E. Kucher, Youssef M. Youssef, Habib Kraiem

Mathematics, Physics, and Computer Science Faculty Articles and Research

Urban heat islands (UHIs) pose critical challenges to public health, energy demand, and environmental sustainability, particularly in rapidly expanding urban regions. This study examines the complex relationship between building configurations and integrated green spaces, as well as their combined impact on thermal regulation. It focuses on addressing data quality issues commonly encountered in remote sensing applications. Using high-resolution multispectral and thermal imagery, we developed an integrated modeling approach that captures the collective influence of built form and green infrastructure on urban microclimates. A key finding is the significant linear inverse relationship between green space coverage and land surface temperature, underscoring …

Women’S Empowerment And Household Decision-Making: The Role Of Socioeconomic Status In Indonesia, Irvel Christa Fabian, Rafa Fayza Afrizal

Jurnal Ekonomi Kependudukan dan Keluarga

Understanding how women's economic, educational, and social positions influence their roles and choices within households is crucial for promoting gender equality and sustainable development. Despite significant advancements in women's rights and gender equality globally, women in Indonesia continue to face substantial barriers in achieving true empowerment. These barriers are particularly evident in domestic settings, where traditional gender roles often persist, limiting women's influence in household decisions. This research aims to investigate the relationship between women's socioeconomic status and their empowerment in domestic decision-making, examining how various factors such as income, education, and employment status contribute to or hinder their ability …

Determinan Kesejahteraan Anak Usia Dini Dalam Keluarga Dengan Kepala Rumah Tangga Perempuan Di Indonesia, Axellina M. Setyanti, Wildan Syafitri

Jurnal Ekonomi Kependudukan dan Keluarga

This study analyzes the determinants of early childhood well-being in female-headed households in Indonesia using data from the 2022 National Socioeconomic Survey (SUSENAS), covering 85,074 households with children aged 0–5 years. Using binary logistic regression, the analysis focuses on four key indicators: complete immunization, food adequacy, access to improved sanitation, and access to safe drinking water. The results show that children in female-headed households are significantly less likely to receive adequate and diverse food as well as complete immunization, compared to those in male-headed households. However, these households are more likely to provide access to improved sanitation and safe drinking …

Kemiskinan Multidimensi Dan Ketahanan Pangan: Analisis Multilevel Di Kalimantan, Lina Agustina Pujiwati, Afriyanni Afriyanni, Dewi Harfina, Zainal Fatoni

Jurnal Ekonomi Kependudukan dan Keluarga

Food security is a crucial issue for sustainable development and is highly influenced by multidimensional poverty. This study measures food security and multidimensional poverty in Kalimantan Island, analyzes the determinants of household food security through a multilevel approach, and explores the influence of multidimensional poverty and regional context on food security. Data were obtained from the March 2022 National Socio-Economic Survey, comprising 33,201 households and integrated with district-level characteristics. Multidimensional poverty was measured using the Alkire-Foster method, while food security was measured based on energy consumption and the proportion of food expenditure. A multilevel ordinal logistic regression was employed to …

Making Intra-Urban Monitoring ‘A Walk In The Park’: A Mobile Monitoring Approach For Assessing Pedestrians’ Environmental Conditions, Cho Kwong Charlie Lam, Halat Alnaqshabandy, Shaun Lewin, Jack Morewood, Xiaoxiong Xie, Steve Goodhew

School of Art, Design and Architecture

Heat island effects and air pollution influence urban climates and air quality, impacting pedestrians’ health, comfort, and well-being. This study develops and pilots the Trolley-based Environmental Monitoring System (TEMS), which was validated in a medium-sized city in the UK. Three monitoring campaigns took place during May and June 2024. The mobile transects covered the city's built and natural environments, including high-density university buildings, museum precinct, medium-density dwellings, highways, and two parks. Appropriate apparatus was specified to monitor environmental variables integrated into a trolley that was easily operated by a single pedestrian. Fisheye photographs were taken to calculate the sky view …

Coastal Archaeological And Environmental Experimental Education At Florida Atlantic University Lab Schools, Katharine Napora, Tricia Meredith, Katherine Henderson, Lauren Simonitis, Jamie Knaub, April A. Watson, Sara Ayers-Rigsby, Alanna L. Lecher, Christian Davenport, Kaiden Merchant, Peter De Witt

Faculty and Staff Publications & Presentations

This presentation focused on a multi-organization project to create an educational midden that students that excavate to learn archaeological and environmental methods.

Husbandry And Management Interventions For The Conservation And Welfare Of Captive Animals – A Systematic Evidence Map, Anaelle Lemasson Lemasson

School of Biological and Marine Sciences

Zoos and aquariums are poised to play increasingly important roles in mitigating the global biodiversity crisis. However, the ultimate success of ex-situ conservation depends on animal welfare and effective husbandry and management practices. As such, an empirical understanding of ‘what works’ in zoo management is crucial for guiding success and embedding cost-effective practices. Here, we present the first systematic evidence map for husbandry and management interventions used in zoos and aquariums. We identified and extracted 1,070 articles spread across 45 journals, and examined patterns within taxonomic, spatial, temporal, and thematic categories. Studies originated from 516 institutions in 69 countries, and …

Resilient Greenport Conceptual Model: Integrating Masterplan With Flood And Land Subsidence Disaster Management, Teuku Khamil Syamsura, Kosuke Mizuno, Supriatna Supriatna

Journal of Environmental Science and Sustainable Development

Hydrometeorological disasters, such as flooding by seawater intrusion and land subsidence from excessive water resource usage, significantly disrupt maritime traffic and port infrastructure, leading to severe economic and social consequences. This study aims to develop a conceptual model for a disaster-resilient and environmentally friendly port. The primary objective is to analyze the components of the Port Masterplan (RIP), the Greenport concept, current operational conditions, and surrounding disaster threats for develop conceptual model. A mixed-methods approach, integrating quantitative and qualitative analyses, was employed. The study examined various components of the Tanjung Priok Port Masterplan, operational data, and environmental and disaster risk …

Assessing The Transformation Of Livelihoods In Illegal Gold Mining Communities, Nurmansyah Ardikoesoema, Mahawan Karuniasa

Journal of Environmental Science and Sustainable Development

Illegal Artisanal Small-Scale Gold Mining (PETI) in Poboya, Palu City, exemplifies Indonesia’s nexus of socio-environmental vulnerability and institutional marginalization. Although environmental degradation, health impacts, and regulatory challenges associated with PETI have been extensively documented, limited research has systematically examined how the interplay of capital assets and internal motivation drives livelihood transformation pathways within PETI communities. To address this gap, this study uniquely integrates the Sustainable Livelihood Framework with spatial analysis to assess the combined influence of environmental, social, and economic capitals on PETI livelihood transitions. Using a mixed-methods approach, data were collected through quantitative survey and qualitative in-depth interviews with …

Environmental Impacts Of Land Use Change In Industrial Areas, Dwi Nowo Martono, Aruminingsih Aruminingsih

Journal of Environmental Science and Sustainable Development

Industrial development in Indonesia has been predominantly concentrated on Java Island, particularly in Karawang Regency, West Java Province. Covering an area of 175,327 hectares, Karawang has been identified as a strategic region for national food security. The Minister of Agrarian Affairs and Spatial Planning designated 95,667.45 hectares of rice fields as protected agricultural land. However, the expansion of industrial and residential areas within the regency poses a significant threat to its role as the national rice granary and to broader food security. As industrial land occupancy increases, the environmental capacity to support rice production and ensure national food security declines. …

Teaching With The Electronic Literature Collection Volume 4, Rui Torres, Kathi Inman Berens, Maria C. Zamora, Lyle Skains, John Murray

English Faculty Publications and Presentations

This article surveys the four ELCs – Electronic Literature Collections (2006- 2022), reviews pedagogical approaches to teaching ELCs, and situates ELCs and electronic literature pedagogy into higher education’s course management systems. ELCs’ increasing accessibility serves its global audience and centers the ethical values of diversity, equality, and inclusion. The ELC4’s user experience design manifests these values. The article discusses the history of the Collections’ experience design. Volume Four (2022) expanded reader accessibility and linguistic diversity by including video playthroughs and collecting 132 works from 42 author nationalities in 31 languages. This article surveys those evolving design changes. It engages a …

Interior As Ecosystem, Paramita Atmodiwirjo, Yandi Andri Yatmo

Interiority

The idea of interior as an ecosystem views the emergence of interior as a dynamic and relational environment. Rather than viewing the interior as a static or enclosed environment, the ecological perspective considers the interior as an ecosystem, constructed by the systems of relations that involve a multiplicity of actors and entities. This issue of Interiority presents the emergence of various interior occupation and adaptation models that have emerged as an integral part of the ecosystem. The collection of articles in this issue presents a range of cases, ranging from traditional, modern, to contemporary lifestyles and contexts. The works demonstrate …