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Acceptance And Commitment Therapy With Huntington's Disease: A Narrative Review And Case Report Of A Caregiver-Assisted Intervention, Simone H. Schriger, Chelsi N. Nurse, C. Virginia O'Hayer Jan 2025

Acceptance And Commitment Therapy With Huntington's Disease: A Narrative Review And Case Report Of A Caregiver-Assisted Intervention, Simone H. Schriger, Chelsi N. Nurse, C. Virginia O'Hayer

Department of Psychiatry and Human Behavior Faculty Papers

Acceptance and commitment therapy (ACT) is an experiential, action-oriented talk therapy that emphasizes acceptance of painful inner experience through increased psychological flexibility. In this narrative review and case report, we first review the extant literature on applications of ACT to patients with a variety of mental and physical health challenges, including neurodegenerative disorders, and their caregivers. We then discuss applications of ACT to Huntington's disease (HD). We provide a case report of a 52-year-old man living with HD who, accompanied by his caregiver, received a virtually-delivered 6-session ACT intervention. We measured the patient's self-reported symptoms of depression (PHQ-9) and anxiety …


Executive Committee - Minutes, 1/28/2025, Academic Senate Jan 2025

Executive Committee - Minutes, 1/28/2025, Academic Senate

Academic Senate Minutes

No abstract provided.


Cross-Platform Analysis Of Mammography Narratives: A Comparative Study On Social Media Engagement, Thomas Stirrat, Jonathan Garner, Parth Tailor, Daniel Weitz, Muhammad Umair, Yusuf T. Akpolat Jan 2025

Cross-Platform Analysis Of Mammography Narratives: A Comparative Study On Social Media Engagement, Thomas Stirrat, Jonathan Garner, Parth Tailor, Daniel Weitz, Muhammad Umair, Yusuf T. Akpolat

Journal of Patient-Centered Research and Reviews

Purpose: This study examines the representation of mammography on social media platforms, specifically, X (Twitter), Facebook, TikTok, and Instagram, from 2006 to 2023. X (Twitter) went public in 2006, Facebook in 2004, Instagram in 2012, and TikTok in 2018 (after merging with Musical.ly). The analysis starts from after the public launch years to analyze personal experiences shared online.

Methods: A retrospective content analysis was conducted on 1,771 posts using specific hashtags related to mammography. Posts were categorized into themes including emotional and psychological impacts, clinical and procedural details, and social and supportive interactions. The analysis involved summarizing the distribution of …


Approved Programs 1-28-25, Angela Brock Jan 2025

Approved Programs 1-28-25, Angela Brock

Programs Committee (PC)

No abstract provided.


Management Of Hip Fracture Patients On Direct Oral Anticoagulants: A Survey Of Orthopaedic Trauma Surgeons, Systematic Review, And Meta-Analysis, Clay Spitler, Robert Rutz, Nigel Blackwood, Meghan Wally, Joseph Johnson, Peter Krause, Jaimo Ahn, Zuhair Mohammed, Mark Mcclure, Rebecca Billings, Ziqing Yu, Matthew Yeager Jan 2025

Management Of Hip Fracture Patients On Direct Oral Anticoagulants: A Survey Of Orthopaedic Trauma Surgeons, Systematic Review, And Meta-Analysis, Clay Spitler, Robert Rutz, Nigel Blackwood, Meghan Wally, Joseph Johnson, Peter Krause, Jaimo Ahn, Zuhair Mohammed, Mark Mcclure, Rebecca Billings, Ziqing Yu, Matthew Yeager

School of Medicine Faculty Publications

OBJECTIVES: This systematic review examined the literature regarding management of fracture patients who take direct oral anticoagulant (DOAC) medications, with a focus on delay in surgical treatment, and need for transfusions. In addition, a survey of orthopaedic trauma surgeons was conducted to gain insight on current practices. DATA SOURCES: A review of PubMed, Cochrane, Embase, and Scopus databases was performed from inception through March 2024, including English language publications. STUDY SELECTION: Studies were included if they reported time to surgery and transfusion rates among fracture patents who were taking DOAC medications. Additional data points were collected on an "if-reported" basis, …


An Innovative Method Of Singular Spectrum Analysis To Conduct Gap-Filling And Denoising On Time Series Data, James J Yang, Anne Buu Jan 2025

An Innovative Method Of Singular Spectrum Analysis To Conduct Gap-Filling And Denoising On Time Series Data, James J Yang, Anne Buu

Faculty, Staff and Student Publications

Heart rate data collected from wearable devices - one type of time series data - could provide insights into activities, stress levels, and health. Yet, consecutive missing segments (i.e., gaps) that commonly occur due to improper device placement or device malfunction could distort the temporal patterns inherent in the data and undermine the validity of downstream analyses. This study proposes an innovative iterative procedure to fill gaps in time series data that capitalizes on the denoising capability of Singular Spectrum Analysis (SSA) and eliminates SSA's requirement of pre-specifying the window length and number of groups. The results of simulations demonstrate …


Screening Young Adult Cancer Patients For Vocational Rehabilitation Services: A Vocational Rehabilitation Readiness Screening Tool, Rhonda Robert, Clark R Andersen, Kathleen M Murphy, Sandra Medina-George, Melissa Scardaville, Sha-Ron Conley, David Farris, Michael Roth, Vinh Nguyen, Lex Frieden Jan 2025

Screening Young Adult Cancer Patients For Vocational Rehabilitation Services: A Vocational Rehabilitation Readiness Screening Tool, Rhonda Robert, Clark R Andersen, Kathleen M Murphy, Sandra Medina-George, Melissa Scardaville, Sha-Ron Conley, David Farris, Michael Roth, Vinh Nguyen, Lex Frieden

Faculty, Staff and Student Publications

Purpose: We aimed to develop an online vocational rehabilitation (VR) readiness screening (VRRS) tool for young adults diagnosed with cancer. VR readiness was defined as being physically and cognitively ready to enter or return to work or school.

Methods: We developed an initial VRRS tool informed by previous studies, a scoping review to determine such a tool had not already been developed, and consultation with subject matter experts. We iteratively refined the tool on the basis of four rounds of interviews with young adults with cancer. The refined VRRS was then administered online to patients before they attended scheduled clinic …


Security Protection For Real-Time Cyber-Physical Systems, Yujie Wang Jan 2025

Security Protection For Real-Time Cyber-Physical Systems, Yujie Wang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Real-time cyber physical systems play increasingly important roles in the real world, operating in environments that are sensitive to timing and encompassing a wide range, from low-end embedded devices such as microcontrollers to high-end platforms such as drones and autonomous vehicles. For computational efficiency, these systems are predominantly written in memory-unsafe languages like C/C++, which can introduce numerous memory safety vulnerabilities and lead to several security issues. Since these systems are often used in safety-critical applications, it is essential to ensure security in addition to timeliness. However, existing security protection mechanisms are primarily designed for general-purpose computing systems, and can …


Sex-Specific Astrocyte Regulation Of Spinal Motor Circuits By Nkx61, Navish A Bosquez Huerta, Zhung-Fu Lee, Eun-Ah Christine Song, Junsung Woo, Yi-Ting Cheng, Debosmita Sardar, Ozlem Sert, Ehson Maleki, Kwanha Yu, Ekin Su Akdemir, Kaitlyn Sanchez, Juyeon Jo, Matthew N Rasband, Hyun Kyoung Lee, Akdes Serin Harmanci, Benjamin Deneen Jan 2025

Sex-Specific Astrocyte Regulation Of Spinal Motor Circuits By Nkx61, Navish A Bosquez Huerta, Zhung-Fu Lee, Eun-Ah Christine Song, Junsung Woo, Yi-Ting Cheng, Debosmita Sardar, Ozlem Sert, Ehson Maleki, Kwanha Yu, Ekin Su Akdemir, Kaitlyn Sanchez, Juyeon Jo, Matthew N Rasband, Hyun Kyoung Lee, Akdes Serin Harmanci, Benjamin Deneen

Faculty, Staff and Students Publications

Astrocytes exhibit diverse cellular and molecular properties across the central nervous system (CNS). Recent studies identified region-specific transcription factors (TF) that oversee these diverse properties; how sex differences intersect with region-specific transcriptional programs to regulate astrocyte function is unknown. Here, we show that the TF Nkx6.1 is specifically expressed in ventral astrocytes of the spinal cord and that its deletion results in sex-specific effects on astrocyte morphology. Astrocytes from males exhibit enhanced morphological complexity, accompanied by increased motor function and cholinergic synapses. In contrast, female astrocytes exhibit reduced complexity and no changes in motor function. Mechanistically, we found that Nkx6.1 …


The Adiponectin-Pparγ Axis In Hepatic Stellate Cells Regulates Liver Fibrosis, Shangang Zhao, Qingzhang Zhu, Wang-Hsin Lee, Jan-Bernd Funcke, Zhuzhen Zhang, May-Yun Wang, Qian Lin, Bianca Field, Xue-Nan Sun, Guannan Li, Mbolle Ekane, Toshiharu Onodera, Na Li, Yi Zhu, Christine M Kusminski, Terry D Hinds, Philipp E Scherer Jan 2025

The Adiponectin-Pparγ Axis In Hepatic Stellate Cells Regulates Liver Fibrosis, Shangang Zhao, Qingzhang Zhu, Wang-Hsin Lee, Jan-Bernd Funcke, Zhuzhen Zhang, May-Yun Wang, Qian Lin, Bianca Field, Xue-Nan Sun, Guannan Li, Mbolle Ekane, Toshiharu Onodera, Na Li, Yi Zhu, Christine M Kusminski, Terry D Hinds, Philipp E Scherer

Faculty, Staff and Students Publications

Hepatic stellate cells (HSCs) are key drivers of local fibrosis. Adiponectin, conventionally thought of as an adipokine, is also expressed in quiescent HSCs. However, the impact of its local expression on the progression of liver fibrosis remains unclear. We recently generated a transgenic mouse line (Lrat-rtTA) that expresses the doxycycline-responsive transcriptional activator rtTA under the control of the HSC-specific lecithin retinol acyltransferase (Lrat) promoter, which enables us to specifically and inducibly overexpress or eliminate genes in these cells. The inducible elimination of HSCs protects mice from methionine/choline-deficient (MCD) diet-induced liver fibrosis, confirming their causal involvement in fibrosis development. We generated …


Robust Cluster Prediction Across Data Types Validates Association Of Sex And Therapy Response In Gbm, David L Gibbs, Gino Cioffi, Boris Aguilar, Kristin A Waite, Edward Pan, Jacob Mandel, Yoshie Umemura, Jingqin Luo, Joshua B Rubin, David Pot, Jill Barnholtz-Sloan Jan 2025

Robust Cluster Prediction Across Data Types Validates Association Of Sex And Therapy Response In Gbm, David L Gibbs, Gino Cioffi, Boris Aguilar, Kristin A Waite, Edward Pan, Jacob Mandel, Yoshie Umemura, Jingqin Luo, Joshua B Rubin, David Pot, Jill Barnholtz-Sloan

Faculty, Staff and Students Publications

Background: Previous studies have described sex-specific patient subtyping in glioblastoma. The cluster labels associated with these "legacy data" were used to train a predictive model capable of recapitulating this clustering in contemporary contexts.

Methods: We used robust ensemble machine learning to train a model using gene microarray data to perform multi-platform predictions including RNA-seq and potentially scRNA-seq.

Results: The engineered feature set was composed of many previously reported genes that are associated with patient prognosis. Interestingly, these well-known genes formed a predictive signature only for female patients, and the application of the predictive signature to male patients produced unexpected results. …


Multisociety Endorsement Of The 2024 European Guideline Recommendations On Coronary Revascularization, Victor Dayan, Joseph F Sabik Iii, Minoru Ono, Marc Ruel, Song Wan, Lars G Svensson, Leonard N Girardi, Y Joseph Woo, Vinay Badhwar, Marc R Moon, Wilson Y Szeto, Vinod H Thourani, Rui M S Almeida, Zhe Zheng, Walter J Gomes, Dawn S Hui, Rosemary F Kelly, Miguel Sousa Uva, Joanna Chikwe, Faisal G Bakaeen Jan 2025

Multisociety Endorsement Of The 2024 European Guideline Recommendations On Coronary Revascularization, Victor Dayan, Joseph F Sabik Iii, Minoru Ono, Marc Ruel, Song Wan, Lars G Svensson, Leonard N Girardi, Y Joseph Woo, Vinay Badhwar, Marc R Moon, Wilson Y Szeto, Vinod H Thourani, Rui M S Almeida, Zhe Zheng, Walter J Gomes, Dawn S Hui, Rosemary F Kelly, Miguel Sousa Uva, Joanna Chikwe, Faisal G Bakaeen

Faculty, Staff and Students Publications

No abstract provided.


The Golgi Complex Governs Natural Killer Cell Lytic Granule Positioning To Promote Directionality In Cytotoxicity, Luis A Pedroza, Frederique Van Den Haak, Alexander Frumovitz, Evelyn Hernandez, Everardo Hegewisch-Solloa, Tabitha K Orange, Keri B Sheehan, Susan Prockop, Aaron Bodansky, Ivan K Chinn, James R Lupski, Jennifer E Posey, Emily M Mace, Yu Li, Jordan S Orange Jan 2025

The Golgi Complex Governs Natural Killer Cell Lytic Granule Positioning To Promote Directionality In Cytotoxicity, Luis A Pedroza, Frederique Van Den Haak, Alexander Frumovitz, Evelyn Hernandez, Everardo Hegewisch-Solloa, Tabitha K Orange, Keri B Sheehan, Susan Prockop, Aaron Bodansky, Ivan K Chinn, James R Lupski, Jennifer E Posey, Emily M Mace, Yu Li, Jordan S Orange

Faculty, Staff and Students Publications

Cytotoxic immune cells mediate precise attacks against diseased cells to maintain organismal health. Their operational unit of killing and host defense is lytic granules (LGs), which are specialized lysosomal-related organelles. Precision in cytotoxicity is achieved by converging the many LGs to the microtubule-organizing center (MTOC) and polarizing these to the diseased cell for secretion. We identify unappreciated intimate relationships between the Golgi, MTOC, and LGs after cytotoxic cell activation, as well as the trans-Golgin protein GCC2 on the LG surface. GCC2 serves to tether LGs to the Golgi following convergence, and both GCC2 and the Golgi are required for the …


Challenges And Opportunities In The Dissemination Of Scientific Content: Insights From Media Professionals In Jordan, Ruba Mustafa Mohammad, Mahmoud Ahmad Al-Rajabi, Hala Nabil Amr Jan 2025

Challenges And Opportunities In The Dissemination Of Scientific Content: Insights From Media Professionals In Jordan, Ruba Mustafa Mohammad, Mahmoud Ahmad Al-Rajabi, Hala Nabil Amr

Middle East Journal of Communication Studies

This study explored the challenges and opportunities in disseminating scientific content from the perspective of media experts in Jordan. Using a descriptive methodology and a questionnaire, the research aimed to understand the landscape better. The sample included 343 media experts holding master's degrees or higher in various media fields, along with several journalists actively working in the sector. The study revealed several key findings. Chief among them are the numerous obstacles hindering the dissemination of scientific content in Jordanian media. These include a lack of training for journalists on accessing new scientific information, a general absence of critical thinking skills …


Music As A Language, Kerrigan Miranda Jan 2025

Music As A Language, Kerrigan Miranda

Acta Cogitata: An Undergraduate Journal in Philosophy

Music has a unique way of communicating that is not tied solely to any one culture or language. Beyond its aesthetic appeal, music possesses inherent characteristics that enable it to function as a language, conveying emotions, ideas, and narratives. Just as words are combined to form sentences and paragraphs in language, music notes are combined to form melodies, harmonies, and rhythms. These notes, rhythms, and melodies of music can be understood and appreciated by people from different parts of the world, regardless of the language they speak. Language is defined as a system of conventional spoken, manual (signed), or written …


Beneath The Same Sky, Damian Shao Hao Lee Jan 2025

Beneath The Same Sky, Damian Shao Hao Lee

Night Flight: Online Literary Journal

No abstract provided.


Carson City Mints A Base Ball Club, 1869–1870, Revised, Mark E. Eberle Jan 2025

Carson City Mints A Base Ball Club, 1869–1870, Revised, Mark E. Eberle

Monographs

Baseball clubs had been organized in Nevada since at least 1866, but the organization of the Silver Star Base Ball Club (BBC) in Carson City in 1869 marked a change for the sport in the state. Some of the employees at the newly constructed Carson City Mint had experience playing for top ball clubs in the East, and other experienced ballplayers lived in the nearby mining community of Virginia City. The Silver City and Virginia clubs initiated intercity competition in 1869. In 1870, the Silver Star BBC picked up players from the Virginia BBC and played six games on a …


Create Engaging Library Resource Lists: Helping Faculty Discover Educational Technologies For Curating And Sharing Library Resources, Allison Faix, Ariana Baker Jan 2025

Create Engaging Library Resource Lists: Helping Faculty Discover Educational Technologies For Curating And Sharing Library Resources, Allison Faix, Ariana Baker

The Southeastern Librarian

Academic libraries have long supported faculty’s use of reading lists. The need for this support has only increased with the growing popularity of distance learning as well as the shifting resource use patterns brought on by online learning during the covid-19 pandemic. However, reading list software can be pro-hibitively expensive while not always meeting faculty needs, and traditional print-based course reserves can only be accessed in person in the library, creating unnecessary barriers for students. This article ex-plores alternatives to commercial reading list software. Librarians can consider promoting these tools to help faculty meet their instructional goals and help students …


Romancing The Gullah In The Age Of Porgy And Bess, Allison Faix Jan 2025

Romancing The Gullah In The Age Of Porgy And Bess, Allison Faix

The Southeastern Librarian

Kendra Y. Hamilton Athens: University of Georgia Press, 2024 ISBN: 9780820362892 266 p. $144.95 (Hbk)


Eng 1002g-003 College Composition Ii Argument And Critical Inquiry, Travis Moody Jan 2025

Eng 1002g-003 College Composition Ii Argument And Critical Inquiry, Travis Moody

Fall 2024

No abstract provided.


Module 2 - Student Workbook, Karon Klipple, Cheryl Hedden Jan 2025

Module 2 - Student Workbook, Karon Klipple, Cheryl Hedden

Module 2 Workbook

No abstract provided.


Assessing The Influence Of An Eastern State's Disciplinary Alternative Education Program On Secondary Student Behavior, Alicia Michelle Gallaway Jan 2025

Assessing The Influence Of An Eastern State's Disciplinary Alternative Education Program On Secondary Student Behavior, Alicia Michelle Gallaway

Walden Dissertations and Doctoral Studies

Services at the local disciplinary alternative education program (DAEP) include counseling and behavioral services to referred secondary students, aiming to improve their behavior. The problem addressed in this quantitative study was that a DAEP was in place in the local district since 2009, but there had been no formal assessment to determine whether differences in student discipline occurred in the semester before and the semester after students attended the DAEP. Guided by Bandura’s social cognitive theory, the purpose of this ex post facto, causal-comparative, quasi-experimental study was to investigate if there was a difference in student discipline as measured by …


The Experience Of Help Seeking For African American Pastors In Personal Crises, Jason Leon Hanna Jan 2025

The Experience Of Help Seeking For African American Pastors In Personal Crises, Jason Leon Hanna

Walden Dissertations and Doctoral Studies

The U.S. population faces enormous challenges coping with disease, financial stress, failure, and general mental health concerns. Rather than seeking care from psychotherapists, increasing numbers of people in religious communities seek help from clergy, who must then balance the needs of their constituents while navigating their own personal crises and need for support. The purpose of this qualitative study was to explore the meaning of help-seeking for African American clergy during personal crises, guided by Ajzen’s theory of planned behavior. Semistructured interviews were conducted with 20 African American senior pastors of congregations in the United States. Study participants defined help-seeking …


Staff Education Project Staff Education To Increase Confidence In Administering Methadone Maintenance, Christelle Meli Jan 2025

Staff Education Project Staff Education To Increase Confidence In Administering Methadone Maintenance, Christelle Meli

Walden Dissertations and Doctoral Studies

Education of health care providers is fundamental in deterring the upward trend in deaths related to opioid drug overdoses. The aim of this staff education project was to educate clinical staff on the importance of administration, and monitoring of methadone maintenance treatment (MMT) to improve treatment rates and patient outcomes in patients with opioid use disorder (OUD). The practice-focused question was, Does an educational program on the importance, administration, and monitoring of MMT increase clinical staff's self-rated confidence in administering MMT? Evidence supported the gap in practice, barriers to MMT, and the need for educational interventions to address gaps in …


Plants, Protests, Pachakuti: How Trees March And How People Tree, Ashley A. Lundquist Jan 2025

Plants, Protests, Pachakuti: How Trees March And How People Tree, Ashley A. Lundquist

Theses and Dissertations

This thesis explores the multi-faceted role of plants, specifically Wituk and Manduru, in Amazonian protests and environmental advocacy. By examining the communicative and relational ontologies inherent in Runa culture, the study elucidates how plants influence social movements and contribute to environmental protection. Wituk and Manduru create paint. Paint facilitates good communication which creates good relationality. Good relationality allows for increased capacities and inhibits greedy consumption allowing for a balanced world order. Through the use and agency of Wituk and Manduru, movements become multi-species phenomena in which ecological entities combine with Runa bodies. The relationships shared between Runa, Wituk, and Manduru …


Faculty Senate Meeting Agenda And Minutes, January 27, 2025 Jan 2025

Faculty Senate Meeting Agenda And Minutes, January 27, 2025

Faculty Senate Minutes and Agendas

Agenda and minutes from the Wright State University Faculty Senate Meeting held on, January 27, 2025.


Hyperlipidemia, Acculturation, And Health Insurance Coverage In United States Foreign-Born Individuals, Debola Olayinka Ola Jan 2025

Hyperlipidemia, Acculturation, And Health Insurance Coverage In United States Foreign-Born Individuals, Debola Olayinka Ola

Walden Dissertations and Doctoral Studies

Hyperlipidemia is one of the modifiable risk factors for cardiovascular diseases (CVD), the leading cause of death among minority populations in the United States, including foreign-born people. Therefore, preventing and treating hyperlipidemia alongside other CVD risk factors is critical for avoiding CVD. Prior research examined disparities in health insurance coverage, length of stay, and blood cholesterol with mixed observations over time with new immigrants. This study aimed to determine if there was a statistically significant association between language spoken at home, length of stay in the United States, having health insurance coverage or none, and high cholesterol level status among …


High School Administrative Staff Experiences During The Covid-19 Pandemic, Woodrow Goss Jan 2025

High School Administrative Staff Experiences During The Covid-19 Pandemic, Woodrow Goss

Walden Dissertations and Doctoral Studies

The COVID-19 pandemic impacted administrative staff members throughout the school system in Texas. The purpose of this study was to explore the experiences of high school administrative staff members who participated in the transition from a traditional high school education delivery environment to an online, distance-based education delivery environment during the COVID-19 pandemic. Self-determination theory was the theoretical foundation for this study and guided the research question and data analysis. The research design was a basic qualitative design using a generic qualitative approach. Purposeful sampling was used to recruit 10 participants from a pool of high school educators who worked …


Transform A Library Corner Into A Social Learning Space, Junli Diao Jan 2025

Transform A Library Corner Into A Social Learning Space, Junli Diao

Open Educational Resources

This library project proposal outlines the essential steps to convert a library corner into a leisure reading space. The proposal includes opening narrative, justifications, work plan, outcome assessment, and budget estimation.


The Free Press Vol. 56, Issue 8, 1-27-2025, Chris Tiner, Cayley Bowman Jan 2025

The Free Press Vol. 56, Issue 8, 1-27-2025, Chris Tiner, Cayley Bowman

Free Press, The

Welcome Back from the Editors--WMPG Welcome Back--ROCC Welcome Back--Libraries and Learning Welcome--Chemistry Club Shines--Editor=in=Chief's Welcome Back