Digital Commons Network^™

Navigating Nonlinear Pathways: Challenges And Opportunities For Diversity, Equity, And Inclusion Leaders In Academic Emergency Medicine, Melanie F Molina, Annika Bhananker, Beatrice Torres, Dalia Owda, Edgardo Ordoñez, Anita N Chary

Faculty, Staff and Students Publications

OBJECTIVES: Diversity, equity, and inclusion (DEI) leadership roles have grown in academic emergency medicine (EM). We sought to elucidate specific pathways to DEI leadership roles among current DEI leaders in academic EM.

METHODS: From March to May 2023, we conducted semistructured, qualitative interviews with DEI leaders in academic EM across 5 US regions to investigate their pathways to leadership. Participants were recruited via email using Accreditation Council for Graduate Medical Education-accredited EM residency websites and the Academy for Diversity and Inclusion in EM. After recording and transcribing the interviews, we used an inductive approach to identify major themes.

RESULTS: Of …

Warm-Ischemia And Cold Storage Induced Modulation Of Ferroptosis Observed In Human Hearts Donated After Circulatory Death And Brain Death, Shiyi Li, Katherine V Nordick, Abdussalam E Elsenousi, Rishav Bhattacharya, Randall P Kirby, Adel M Hassan, Camila Hochman-Mendez, Todd K Rosengart, Kenneth K Liao, Nandan K Mondal

Faculty, Staff and Students Publications

We investigated ferroptosis, a type of programmed cell death mechanism, in human hearts donated after brain death (DBD) and those donated after circulatory death (DCD), focusing on warm ischemia time (WIT) and cold storage. A total of 24 hearts were procured, with six from the DBD group and 18 from the DCD group. The DCD group was divided into three subgroups, each containing six hearts, based on different WITs of 20, 40, and 60 min. All procured hearts were placed in cold storage for up to 6 h. Left ventricular biopsies were performed at 0, 2, 4, and 6 h. …

Time Tracking And Comparison Of Genetic Counseling Tasks In Inpatient And Outpatient Settings, Alexandra Osborne, Emily Magness Bland, Callie Diamonstein, Kristen Fishler

Faculty, Staff and Students Publications

Genetic counselors (GCs) practice in critical care settings. Some GCs have full-time inpatient roles, while most GCs who see inpatients do so as needed or on a rotating schedule in addition to seeing patients in an outpatient setting. Few studies have tracked and compared the amount of time it takes GCs to perform tasks in the inpatient and outpatient settings. Genetic counselors were invited to participate in this study via the National Society of Genetic Counselors research listserv. Participants completed an online survey asking how their role is structured and what types of support are available to them while seeing …

Citation Issues In The American Academy Of Pediatrics Policy Statement On Transgender And Gender-Diverse Children And Adolescents (Rafferty, 2018), Kathleen Mcdeavitt

Faculty, Staff and Students Publications

No abstract provided.

Destructive And Protective Effects And Therapeutic Targets Of Il-36 Family Cytokines In Dry Eye Disease, Xin Chen, Na Lin, Haixia Liu, Jing Lin, Ning Gao, Zhao Liu, Cintia S De Paiva, Stephen C Pflugfelder, De-Quan Li

Faculty, Staff and Students Publications

Purpose: To explore the destructive and protective effects and therapeutic targets of IL-36 cytokines in dry eye disease using a murine dry eye model.

Methods: A dry eye model was established in C57BL/6 mice exposed to desiccating stress (DS) with untreated mice as controls. A topical challenge model was performed in normal mice with exogenous rmIL-36α, rhIL-38 and 2 % ectoine, or PBS vehicle. IL-36 cytokine expression was assessed by RT-qPCR and immunofluorescent (IF) staining. Corneal epithelial damage was evaluated by corneal smoothness score, Oregon Green Dextran (OGD) fluorescent staining, and tight junction barrier.

Results: All members of the IL-36 …

Who And Its Enduring Commitment To Global Pediatrics, Peter J Hotez

Faculty, Staff and Students Publications

No abstract provided.

Klf4 Enhances Transplantation-Induced Hematopoiesis By Inhibiting Tlrs And Noncanonical Nfκb Signaling At A Steady State, Chun Shik Park, Cory S Bridges, Andrew H Lewis, Taylor J Chen, Saptarsi Shai, Wa Du, Monica Puppi, Barry Zorman, Sumazin Pavel, H Daniel Lacorazza

Faculty, Staff and Students Publications

The transcription factor Krüppel-like factor 4 (KLF4) acts as a transcriptional activator and repressor. KLF4 plays a role in various cellular processes, including the dedifferentiation of somatic cells into induced pluripotent stem cells. Although it has been shown to enhance self-renewal in embryonic and leukemia stem cells, its role in adult hematopoietic stem cells (HSCs) remains underexplored. We demonstrate that conditional deletion of the Klf4 gene in hematopoietic cells led to an increased frequency of immunophenotypic HSCs in the bone marrow, along with a normal distribution of lymphoid and myeloid progenitor cells. Noncompetitive bone marrow transplants showed normal engraftment and …

Unveiling Racial Disparities In Prostate Cancer Using An Integrative Genomic And Transcriptomic Analysis, Abdalla Elbialy, Akshay Sood, Shang-Jui Wang, Peng Wang, Ahmed Fadiel, Anil V Parwani, Steven Huang, Gennady Shvets, Nagireddy Putluri, Jenny Li, Xuefeng Liu

Faculty, Staff and Students Publications

Prostate cancer exhibits significant racial disparities, with African American (AA) individuals showing ∼64% higher incidence and 2.3 times greater mortality rates compared to their Caucasian (CA) counterparts. Understanding the complex interplay of genetic, environmental, lifestyle, socioeconomic, and healthcare access factors is crucial for developing effective interventions to reduce this disproportionate burden.

This study aims to uncover the genetic and transcriptomic differences driving these disparities through a comprehensive analysis using RNA sequencing (RNA-seq) and exome sequencing of prostate cancer tissues from both Black and White patients.

Our transcriptomics analysis revealed enhanced activity in pathways linked to immune response and cellular interactions …

Telehealth Is Effective In The Evaluation Of Individuals With Undiagnosed Rare Disorders: An Undiagnosed Diseases Network Study, Queenie K-G Tan, Allyn Mcconkie-Rosell, Rachel Mahoney, Rebecca C Spillmann, Kelly Schoch, Sirisak Chanprasert, Maria T Acosta, Camilo Toro, Jill A Rosenfeld, James P Orengo, Daryl A Scott, Jorge L Granadillo, Kathleen Sisco, Daniel J Wegner, Mustafa Tekin, Stephanie Bivona, Léshon Peart, Lance Rodan, Devon Bonner, Matthew T Wheeler, Jonathan A Bernstein, Maura Ruzhnikov, Undiagnosed Diseases Network, David R Adams, Fuki M Hisama, Vandana Shashi

Faculty, Staff and Students Publications

Patients with undiagnosed and/or rare disorders frequently manifest dysmorphic and neurological features. There is a lack of information on the effectiveness of telehealth in the evaluation of these disorders. We thus compared an unassisted virtual physical examination (PE) with an in-person PE in undiagnosed individuals and also assessed participant telehealth satisfaction. Twenty-six individuals enrolled in the Undiagnosed Diseases Network study underwent an in-home synchronous virtual PE, and a subsequent in-person PE, by the same clinician. The participants completed surveys on telehealth usability and provider empathy. On PE, general appearance and craniofacial features showed near perfect agreement (κ = 0.81-1.00) between …

The Emergence Of Artificial Intelligence-Driven Reservation Services Analyzed Through Push-Pull-Mooring Theory And Their Potential To Enhance Tourism Experiences, Dimitra Skandali, Muhammad Ali Raza

Journal of Global Hospitality and Tourism

Artificial intelligence-based bath bed reservation services signify a novel evaluation of consumer behavior in densely populated tourist destinations. The phenomenon of overcrowded beaches, particularly during the peak summer months at well-known public beaches in Europe, has increased demand during rush hours. The research aims to clarify the key factors that influence the use of these applications, primarily on mobile phones, by applying the Push-Pull-Mooring Theory, in addition to identifying the primary causes of the high demand and the importance of staying close to the shore when sunbathing. The study emphasizes the impact of perceived risk and enjoyment on user behavior, …

The Impact Of Rubric-Based Feedback On Efl Writing Proficiency: Exploring Revision Skills And Learning Transfer, Ahmed Abdelraheem Elyan

Theses

This study explores how rubric-based feedback influences the writing development of English as a Foreign Language (EFL) learners, with a particular focus on their revision practices, learning transfer, and the challenges they face with cognitive overload. The research was carried out in a high school context in the United Arab Emirates (UAE), aiming to understand the real impact of structured feedback on students’ writing performance.

Twenty Arabic-speaking students participated in the study, completing four essay writing tasks over eight weeks. These included a pre-test, two feedback-supported drafts, and a post-test. Their essays were assessed using an analytic rubric designed to …

Know Where You Go: Infestation Dynamics And Potential Distribution Of Two Bed Bug Species (Hemiptera: Cimicidae) In Africa, Dennis M. Mbuta, Bonoukpoè M. Sokame, Fathiya M. Khamis, Komivi S. Akutse

All Peer-Reviewed Publications

Bed bugs (Hemiptera: Cimicidae) are blood-feeding insects closely linked with humans and animals, causing discomfort, and posing potential threats as disease vectors. This study focuses on Cimex lectularius (common bed bug) and Cimex hemipterus (tropical bed bug), the two key species identified in Africa. Cimex lectularius infests human habitats, while C. hemipterus, more common in Africa, infests diverse habitats, including bat colonies. In our study, we investigated the infestation dynamics and distribution of bed bugs in Africa, when considering climate, habitat, and host availability using system dynamics and ecological niche modelling techniques. System dynamics modelling analyses in Kenya revealed varied …

Cultivation Of Global Competencies In The Post-Covid-19 Era: A Multinational Survey, Reiko Yamada, Rie Mori, Yumiko Sugitani, Takurya Kimura, Shihwei Sun

Journal of Comparative & International Higher Education

No abstract provided.

Interpretative Phenomenological Analysis Of Wellbeing Of An International Student With Depression And Suicidality From A Coping Perspective, Rumiko Nakano

Journal of Comparative & International Higher Education

No abstract provided.

Students On The Move: Assessing Intercultural Competence Of American Study Abroad Sojourners In Japan And Korea, Jeongi Lee, Kathryn Negrelli

Journal of Comparative & International Higher Education

No abstract provided.

Perspectives Of Support Services Among Non-Traditional International Students: A Phenomenological Exploration, Christian M. Gallie, Robert A. Griffin

Journal of Comparative & International Higher Education

No abstract provided.

Comparative And International Higher Education And The Aid Sector Graduate Pipeline, Zeena Zakharia, Deepa Srikantaiah, Shytance Wren, Langan Courtney, Katya Murillo

Journal of Comparative & International Higher Education

No abstract provided.

Transporting Hbcu Students To Morocco Through Films: Action Research And Reflection On A Piloted Course, Roger W. Anderson

Journal of Comparative & International Higher Education

No abstract provided.

Estimation And Inference In A Possibly Multicointegrated System With A Fixed Number Of Instruments, Yixiao Sun, Peter C. B. Phillips, Igor L. Kheifets

Research Collection School Of Economics

This paper shows that the mixed normal asymptotic limit of the trend IV estimator with a fixed number of deterministic instruments (fTIV) holds in both singular (multicointegrated) and nonsingular cointegration systems, thereby relaxing the exogeneity condition in (Phillips and Kheifets, 2024, Theorem 1(ii)). The mixed normality of the limiting distribution of fTIV allows for asymptotically pivotal F and t tests about the cointegration parameters and for simple efficiency comparisons of the estimators for different numbers K of instruments, as well as comparisons with the trend IV estimator when K→∞ with the sample size.

Statistical Inference For Noisy Matrix Completion Incorporating Auxiliary Information, Shujie Ma, Po-Yao Niu, Yichong Zhang, Yinchu Zhu

Research Collection School Of Economics

This article investigates statistical inference for noisy matrix completion in a semi-supervised model when auxiliary covariates are available. The model consists of two parts. One part is a low-rank matrix induced by unobserved latent factors; the other part models the effects of the observed covariates through a coefficient matrix which is composed of high-dimensional column vectors. We model the observational pattern of the responses through a logistic regression of the covariates, and allow its probability to go to zero as the sample size increases. We apply an iterative least squares (LS) estimation approach in our considered context. The iterative LS …

The Epidemiology Of Major Congenital Anomalies In The United Arab Emirates: The Mutaba'ah Study, Hiba Mahdi Adam

Dissertations

Major Congenital Anomalies (MCAs) are significant contributors to perinatal morbidity and mortality. The absence of clear baseline prevalence data for MCAs hinders the development of targeted interventions to mitigate their burden. Furthermore, studies on adverse obstetric and birth outcomes in pregnancies complicated by MCAs are scarce, emphasizing the need for research to enhance management strategies. This dissertation aimed to: (1) estimate the live birth prevalence of perinatally diagnosed MCAs and describe study population characteristics by MCA status, (2) investigate the impact of MCAs on fetal presentation and delivery mode, and (3) investigate the impact of MCAs on preterm and low …

It Ends With Us: How Social Media Algorithms Shape Recommendations In Online Reading Communities, Alana Nicole Whitley

Communication & Theatre Arts Theses

My thesis explores social media algorithms and their influence on recommendations of authors for people who engage with reading communities online. During a three-week research period, I examined algorithmic behaviors in online book communities using an alias. Findings revealed that BookTube, BookTok, and Bookstagram facilitate book discovery but offer weak algorithmic recommendations and suggestions. While social media algorithms excel at providing opportunities for creators and authors, they fail to promote trending and diverse books. These insights indicate that algorithms shape literary consumption by limiting readers’ choices. This research contributes to discussions of online reading communities and the role of algorithmic …

Historic Bedrocks Of Volunteer Recruitment: Collaboration Between The Peace Corps And Higher Education Partners, Melanie Elizabeth Graham

Educational Leadership & Workforce Development Theses & Dissertations

In this study I investigate the collaboration between the United States Peace Corps and their higher education partnership institutions, focusing on Peace Corps Prep Programs (PCPP) which aim to recruit, prepare, and retain diverse Peace Corps Volunteers. The inquiry examines the purpose, structure, and process of these collaborations to uncover successes and shortcomings, shedding light on the underlying mechanisms that contribute to effectiveness or hinder progress. A mixed-method, multiple case study methodology, integrating surveys and individual interviews that parallel The Wilder Collaboration Factors Inventory, facilitates an in-depth examination of the intricate dynamics and multifaceted experiences within the collaborative partnerships. By …

Hieronymus Bosch’S Dismantled Triptych As A Moralizing Guide For Reforming The Catholic Church, Heather Thurston

Institute for the Humanities Theses

This thesis expands on the current interpretation of a dismantled triptych by the Dutch painter Hieronymus Bosch, which includes four extant panels: Ship of Fools, Allegory of Intemperance, Death and the Miser, and The Wayfarer. Current scholarship claims that the paintings warn viewers against various sins. This thesis argues that the triptych was specifically directed toward the Catholic Church and functions as a commentary on the potential consequences of their sins. This new reading will become clear by examining and connecting its unorthodox iconography to the tumultuous religious climate at the turn of the sixteenth century …

Designerly Skills: An Educational Design Research Study On K-5 Teacher-Designers N Trauma-Informed Technology-Enhanced Learning Environments, Kristin Marie Herman

STEMPS Theses & Dissertations

This study explored how K-5 teachers exhibit designerly skills when creating trauma-informed, technology-enhanced learning environments. While teachers have long been recognized as designers, asset-based research on their specific designerly skills, particularly in trauma-informed digital spaces, remains limited. Using an educational design research (EDR) approach focused on research-for-interventions, this study examined which skills teachers consider essential and how these skills manifest in course designs supporting student belonging.

The study employed a multi-method qualitative approach over 12 months, following 23 K-5 teachers and administrators engaged in designing Canvas courses. Data collection included reflective discussion boards, design studio sessions, individual think-aloud protocols, and …

The Compass - Volume 94 Issue 2 - Complete Issue, Scott R. Beason

The Compass: Earth Science Journal of Sigma Gamma Epsilon

No abstract provided.

From A Learning To A Smart Nation: The Rise Of The Digitalization Megatrend And Singapore's Development, Siu Loon Hoe

Research Collection School Of Computing and Information Systems

Purpose: The purpose of this article is to discuss the “learning nation” concept and examine the characteristics and implications of using the “learning” premodifier in this nation-building program. Design/methodology/approach: This article reviews how the “learning” aspect is inter-related to a series of national information and communication technology masterplans and includes a comparative analysis of the related premodifier “smart” as Singapore sets forth its ambition to become a “smart nation” as part of the digitalization megatrend. A print media indicator and Google Trends form part of the methodology to ascertain the rise of digital technology over a certain period. The former …

Enmob: Unveil The Behavior With Multi-Flow Analysis Of Encrypted App Traffic, Mengmeng Ge, Ruitao Feng, Likun Liu, Xiangzhan Yu, Sachidananda Vinay, Xiaofei Xie, Yang Liu

Research Collection School Of Computing and Information Systems

In the contemporary digital landscape, mobile applications have become the predominant conduit for internet connectivity and daily tasks. Simultaneously, the advent of application encryption technology has safeguarded users’ privacy. However, this encryption, while fortifying privacy, introduces challenges to security by hindering the effective management of network applications within encrypted data streams. Conventional detection methods for encrypted application traffic, relying heavily on statistical metrics like payload, packet size, and distribution, are constrained to single traffic flows, often yielding results of limited specificity. To address this limitation, our paper introduces an innovative approach that elucidates the multi-flow nature of application behavior traffic …

Verification Of Bit-Flip Attacks Against Quantized Neural Networks, Yedi Zhang, Lei Huang, Pengfei Gao, Fu Song, Jun Sun, Jin Song Dong

Research Collection School Of Computing and Information Systems

In the rapidly evolving landscape of neural network security, the resilience of neural networks against bit-flip attacks (i.e., an attacker maliciously flips an extremely small amount of bits within its parameter storage memory system to induce harmful behavior), has emerged as a relevant area of research. Existing studies suggest that quantization may serve as a viable defense against such attacks. Recognizing the documented susceptibility of real-valued neural networks to such attacks and the comparative robustness of quantized neural networks (QNNs), in this work, we introduce BFAVerifier, the first verification framework designed to formally verify the absence of bit-flip attacks against …

The Lao Penal Code: A Comparative Discourse, Wing Cheong Chan, Wing Cheong Chan, Phanthasak Mingnakhone, Perrine Simon, Stanley Yeo

Research Collection Yong Pung How School Of Law

This book comprises a commentary on the criminal law of Laos dealing with the general principles of criminal responsibility, and describing the main offences against the person and property under the Lao Penal Code 2017.