Digital Commons Network^™

Tranexamic Acid In High-Risk Shoulder Arthroplasty Patients: Safety Across Thromboembolic, Cardiac, Renal, And Neurologic Risk Profiles, Tarishi Parmar, Akin Adio, Asim Handy, Mohammad Daher, Alec Kellish, Adam Khan, Joseph A. Abboud

Rothman Institute Papers

INTRODUCTION: Tranexamic acid (TXA) effectively reduces blood loss and transfusion requirements in shoulder arthroplasty. However, concerns regarding thromboembolic, neurologic, cardiac, and renal complications have limited its use in medically high-risk patients. This study evaluated temporal trends and the safety of TXA in high-risk patients undergoing total shoulder arthroplasty (TSA).

METHODS: A retrospective cohort study was conducted using TriNetX, identifying patients who underwent shoulder arthroplasty (2012-2025). Patients were stratified by preexisting high-risk conditions, including prior thromboembolism, renal failure, atrial fibrillation, seizure disorders, and visual disturbances. Within each subgroup, patients receiving TXA were propensity score-matched to those who did not. Perioperative TXA …

Childhood Development Podcast Assignment, Masha Komolova

Open Educational Resources

The assignment asks students to analyze how a particular aspect of their childhood has shaped them into a person they are today. Students will use literature review, interview with a caregiver, and their own reflection to analyze their childhood development and its effects on them. The assignment will be in the form of a podcast.

Ai-Resistant And Ai-Resilient Assessment In Higher Education: A Systematic Review Of Validity-Grounded Strategies, Institutional Frameworks, And Equity Implications, Asrat Genet Amnie

Publications and Research

The emergence of large language models has precipitated a fun damental disruption to higher education assessment. Conventional instruments are susceptible to AI-assisted completion, threatening construct validity across disciplines and institutional contexts. When submitted work reflects AI capability rather than student competency, the inferential chain from performance to qualifica tion is invalidated – a problem of design rather than detection. This systematic review makes two contributions. First, it theorises and grounds the distinction between AI-resistant assessment, which seeks to prevent or impede AI access through containment, and AI-resilient assessment, which assesses genuine human cogni tive performance of intrinsic educational value regardless …

Advancing Bioinformatics With Language Models: Components, Applications, And Perspectives, Jiajia Liu, Mengyuan Yang, Yankai Yu, Haixia Xu, Tiangang Wang, Kang Li, Xiaobo Zhou

Faculty, Staff and Student Publications

Large language models (LLMs) are deep learning-based artificial intelligence models that have achieved remarkable success in natural language processing. Typically composed of neural networks with billions of parameters, they are trained on massive unlabeled datasets using self-supervised or semi-supervised learning. Beyond language, LLMs hold immense potential for addressing complex bioinformatics challenges. This review provides a comprehensive overview of transformer-based model applications in genomics, transcriptomics, proteomics, drug discovery, and single-cell analysis. We discuss critical components, including tokenization strategies for diverse biological data, transformer architectures, attention mechanisms, and pretraining approaches. We also survey currently available foundation models and their downstream applications across …

The Role Of Cross-Cultural Connections In Leadership Identity Development: From Entry To Embodiment, Jennifer Okoliko

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Leadership identity development has received considerable attention in the literature, but most of what we know comes from studies focused on students in formal leadership programs or on the mentee’s side of mentoring relationships. Less understood is the mentor's leadership identity development journey and the role of culture in that process.

This study explores how mentors from low power distance cultural backgrounds who engaged with mentees from high power distance cultural backgrounds interpreted the impact of those experiences on their leadership identity development.

Using Interpretive Phenomenological Analysis (IPA), I conducted two semi-structured interviews with ten participants recruited from different formal …

Development Of An Optimal Composition Of A Composite Solvent For Asphalt–Resin–Paraffin Deposits, Gulmira Abduvaliyevna Tadjiyeva, Xasan Irgashevich Kadirov, Shaxnoza Abduvaliyevna Tadjiyeva, Fazliddin Zokir Ugli Murodullayev, Bekmurodjon Baxtiyorjon Ugli Raximjonov

Technical science and innovation

A solvent formulation composed of aromatic hydrocarbons of the C9 fraction and aliphatic alcohols in a 1:1 ratio, supplemented with 1–3 wt.% of a nonionic surfactant, has been developed. The proposed composition demonstrates more than a twofold increase in dissolving and washing efficiency toward paraffin-type asphaltene–resin deposits. Furthermore, the solvent system exhibits pronounced depressant–dispersant properties with respect to paraffin-containing organic deposits. Although numerous investigations have addressed the development of technologies for removing organic deposits in oilfield equipment—primarily focusing on specific aspects of eliminating or preventing asphaltene–resin–paraffin deposits (ARPD) in wells—limited attention has been given to the design of integrated approaches. …

Use Of New Improved Methods For Assessing The Engineering-Geological Characteristics Of Deposits By Depth (Using The Example Of The Akba Deposit)., Elboy Shavkatovich Qurbonov Salom, Abduboqib Djalilovich Karimov, Yokub Yarash Ugli Isomiddinov

Technical science and innovation

The article examines the fracturing and filtration properties of rocks in boreholes, rock outcrops, and underground mine workings at the Akba gold deposit. Based on the results of hydrogeological and engineering-geological studies, methods that fully meet modern requirements were used, the values of the RMR rating of rocks and the indicators of the qualitative content of RQD rocks, as well as the intervals of their changes, were studied, as a result of which it became possible to quickly and accurately assess the strength state of the rock mass of the deposit territory by depth and area.

Techedu.Uz: A Web-Based Virtual Laboratory Platform For Studying Induction Heating Processes., Abror Obidovich Pulatov, Murat Fikhratovich Shamiyev, Kutbiddin Asliddin Ugli Boboniyozov

Technical science and innovation

The challenges of integrating high-voltage induction furnace equipment into university laboratory settings were examined, including prohibitive equipment costs, limited student capacity, and serious safety risks. A conceptual design was proposed for a web-based platform called TechEdu.uz, which integrates both a Remote Laboratory module and a Virtual Laboratory module for induction furnace study within a single interface. The Remote module was designed to enable users to start, control, and monitor a real induction crucible furnace via a web interface, with live video surveillance and sensor devices intended to provide real-time measurements of temperature, power, and current values. The Virtual module was …

Ideology In Translating Indonesian Political News Headlines From Indonesian To English: A Cda Study Of Antara, Ferina A. Lestari, Haru Deliana Dewi

Journal of Language, Literature, and Arts

This study examines how ideology is constructed in the translation of Indonesian political news headlines into English by ANTARA News Agency. Moving beyond the notion of translation as mere equivalence, it conceptualizes headline translation as a process of discursive recontextualization shaped by institutional practices and audience design. Using a qualitative comparative approach, the study analyses 20 pairs of Indonesian English political headlines. The analysis implied Fairclough’s (1995) three-dimensional Critical Discourse Analysis (CDA) framework. The dimensional focusing on textual features, discourse practice, and social practice. The findings reveal transformations, including omission of culturally specific details, addition of evaluative elements, lexical reframing, …

A Systematic Survey Of Brachyuran Land Crabs In The Online Tropical Aquarium Trade, Ella Xanthe Whitaker, David L. Roberts, John I. Spicer, Lucy Millicent Turner

School of Biological and Marine Sciences

Globally the tropical aquatic aquarium trade is a multi-million-dollar industry. Although marine ornamental fish and invertebrates are the main focus, tropical freshwater ornamental species including invertebrates (classed by the sector as semi-aquatic, such as land crabs) are also traded. Land crabs include both brachyurans (true crabs) and anomurans (false crabs, including hermit crabs). These are sourced from wild populations and/or tank-bred for use as ornamental commodity species. This global trade is unregulated and the full extent of the brachyuran land crab trade is unknown. Land crabs are important ecosystem engineers, and collection for the tropical freshwater/semi-aquatic aquarium industry is believed …

Optimization Of Aluminum Coating Deposition Parameters To Enhance The Performance Of Automotive Headlamps, Gulirano Saidakhmedova, Giovanni Maizza

Technical science and innovation

The paper investigates the influence of the optical characteristics of functional coatings applied to automotive reflectors on vehicle active safety parameters, with a focus on the range and intensity of road illumination. The study examines the mathematical relationship between the maximum luminous intensity of a headlamp, the object detection distance, and the reflection coefficient  of an aluminium layer deposited via vacuum thermal evaporation. The main factors driving the degradation of surface reflectivity (including oxidation, thermal degradation of the base coat, and surface roughness) are analysed. It is demonstrated that a decrease in the reflection coefficient during operation directly impairs the …

Experimental Study Of An Automotive Cooling System With A Mechatronic Control System, Avaz Israilovich Yangibayev

Technical science and innovation

This article presents the results of experimental investigations of a passenger car engine cooling system equipped with a mechatronic control system. The experiments were conducted on an intelligent hardware-software laboratory test bench developed using original components of a Chevrolet Gentra vehicle. The study determined the thermodynamic response characteristics and energy performance of the system under varying ambient temperatures (-10 to +50 °C) and engine thermal loads. The experimental results demonstrated that the mechatronic system can maintain coolant temperature with minimal fluctuation amplitude, ensure smooth transient processes, and significantly reduce electrical energy consumption. Based on the obtained results, scientific and practical …

Technology For Obtaining Aliphatic Amines Based On Liquid By-Products Of Polymerization Processes, Kamila Sabirbaevna Allanazarova, Ulugbek Komiljonovich Urinov

Technical science and innovation

Polymerization processes generate considerable amounts of liquid secondary by-products, which are often underutilized despite their significant chemical potential. Addressing the need for sustainable resource use, this study aims to develop a technological method for converting these by-products into valuable aliphatic amines. The experimental approach involved the pre-treatment of liquid polymerization by-products through fractional distillation to isolate C3–C10 fractions, followed by catalytic amination using Raney nickel under controlled temperature (160°C) and pressure (12 atm) conditions. Analytical methods including gas chromatography-mass spectrometry (GC-MS) and Fourier-transform infrared spectroscopy (FTIR) were employed to characterize the reaction products. The results demonstrated the successful formation of …

Investigation Of Energy Efficiency Of An Autonomous Mobile Photovoltaic-Thermal (Pv/T) System With A Polycarbonate Absorber, Sanjar Kodir Ugli Shoguchkarov, Anvar Rakhmat Ugli Rakhmatov, Rushana Husen Kizi Abdullaeva, Orazbek Maratbay Ugli Temirbaev

Technical science and innovation

This study analyzes the enhancement of energy efficiency in photovoltaic-thermal (PV/T) systems, which enable the simultaneous generation of electrical and thermal energy from solar radiation. The research focus is an autonomous mobile unit based on multi-channel polycarbonate heat collectors with a hydraulic diameter of 8 mm, characterized by their lightweight nature and superior corrosion resistance compared to conventional metal absorbers. Experimental investigations were conducted at the solar testing field of the Physical-Technical Institute of the Academy of Sciences of Uzbekistan under extreme continental climatic conditions to determine the system's stable thermophysical indicators. The results demonstrated that active water cooling using …

Modeling Of Terpolymerization Kinetics And Determination Of Reactivity Ratios In The Tdma–Styrene–Maleic Anhydride System, Shohrux Boboxon Ugli Mavlonov, Sadriddin Fayzullayevich Fozilov

Technical science and innovation

In this study, the kinetics of terpolymerization, compositional evolution, and monomer reactivity ratios in the TDMA–styrene–maleic anhydride system were comprehensively investigated. Increasing the initiator concentration from 16.8×10⁻⁶ to 51.3×10⁻⁶ mol•L⁻¹ led to an increase in conversion from 6.4% to 15.2% and reaction rate from 4.075×10⁻⁶ to 8.965×10⁻⁶ mol•L⁻¹•s⁻¹. At low conversion (Xw≈0.02–0.09), the terpolymer composition remained close to the initial feed, although deviations due to differences in monomer reactivity were observed. With increasing conversion, some systems exhibited stable composition (±0.02), while others showed compositional drift (increase of MA fraction from 0.50 to 0.70). The determined reactivity ratios (rTDMA/St≈0.99; rSt/TDMA≈1.62; rTDMA/MA≈2.02; …

Adaptive – Compositional Method For Coordinating Subsystems At Different Levels In Hierarchical Control Systems, Husan Zakirovich Igamberdiyev, Uktam Farxodovich Mamirov Mr, Inomjon Ilxom Ugli Abdukaxxarov Mr

Technical science and innovation

This paper examines the problem of synthesizing algorithms for the composition of subsystems at various levels within complex hierarchical control systems under conditions of uncertainty and resource constraints. It is demonstrated that classical composition algorithms, which rely on the intersection of admissible sets and the use of local optimality criteria, suffer from several significant drawbacks. These include a combinatorial increase in complexity, dependence on the expert selection of parameters, and limited applicability in dynamic environments. To overcome these shortcomings, an adaptive-compositional method is proposed. This method is based on the dynamic recalculation of coordination parameters, the integration of model predictive …

Calculation Of The Basic Parameters Of The Hybrid Power Plant (Hpu) On The Spark Car, Rustam Raximovich Tillahodjaev, Jamoliddin Pardaboy Ugli Turdiev

Technical science and innovation

This article presents one of the effective ways to improve fuel efficiency and reduce emissions of toxic substances, the use of internal combustion engines with the use of an electric drive in their designs. In recent years, two directions in the development of cars with electromechanical drives have been clearly identified, the first is the creation of a pure electric car, the second is the development of an electromechanical drive with a combined (hybrid) power plant. Due to the lack of efficient energy storage available for mass production, pure electric vehicles have relatively low mileage on a single charge. This …

Elective Genomic Sequencing For Adults In Research, Clinical And Commercial Contexts, Michael D Linderman, Sophia M Adelson, Tala M Berro, Jennifer L Anderson, Scott D Crawford, Tshaka J Cunningham, Edward D Esplin, Altovise T Ewing-Crawford, Daiva E Nielsen, Stacey Pereira, Tara Schmidlen, Heather Andrighetti, Steven B Bleyl, George M Church, Eden V Haverfield, Madhuri Hegde, Lazaridis N Konstantinos, Paul Kruszka, Debra Leonard, Thomas May, Molly Mcginniss, Vaibhav Pandya, Eric E Schadt, Bastian Greshake Tzovaras, Bethany Zettler, Amy L Mcguire, Robert C Green

Center for Medical Ethics and Health Policy Staff Publications

Purpose: Elective genomic sequencing (EGS) returns monogenic disease findings in multiple genes, including potentially novel variants, and may also provide participants with carrier status, pharmacogenomic and other health-related information. The PeopleSeq Study assessed participants' motivations for and concerns about EGS and the associated clinical and psychosocial outcomes across diverse EGS providers.

Methods: We administered a shared questionnaire to participants who chose to undergo EGS via 18 academic, clinical, or commercial EGS platforms.

Results: We enrolled 1575 participants, of whom 1147 (72.8%) completed a questionnaire after receiving their EGS results. A majority (60.3%) of the participants who completed a post-result questionnaire …

Multiplexed Plasmon-Enhanced Lateral Flow Assay For Early Diagnosis Of Acute Kidney Injury, Heng Guo, Yuxiong Liu, Ravi Jada, Ying Liu, Carissa Ng, Aquiles Payte, Jiaying Xu, Connor Malone, Jie Zhao, Kedhareswara Sairam Pasupuleti, Arda Aidan Arikan, Sameer Thadani, Srikanth Singamaneni, Ayse Akcan Arikan, Limei Tian

Faculty, Staff and Students Publications

Early diagnosis of acute kidney injury (AKI) remains a major clinical challenge due to the delayed and insensitive nature of conventional markers such as serum creatinine. Urinary protein biomarkers, including neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C (CysC), provide earlier and complementary information on kidney injury, but their clinical translation is limited by the lack of rapid, quantitative, and multiplexed point-of-care (POC) diagnostic tests. Here, we report a multiplexed plasmonic-fluor-based lateral flow assay (p-LFA) that enables sensitive, quantitative, and simultaneous detection of NGAL and CysC. By harnessing ultrabright plasmonic-fluor nanolabels and ratiometric fluorescence analysis, the p-LFA achieves picogram-per-milliliter analytical sensitivity …

Adapting And Delivering An Extension Diabetes Self-Management Support Program To Serve The Hispanic Community, Camden Bryan, Samantha Kanny, Christina Dietz, Danielle Mcfall, Michelle Parisi, Michelle Stancil, Johanna Bruen, Rhonda Matthews, Windsor W Sherrill

Journal of Extension

Expanding Extension education programs to serve the Hispanic community will be important as this population continues to grow. The rate of diabetes is higher among the Hispanic population than the non-Hispanic population; however, the barriers to implementing a health education program and recruiting participants are plentiful. This paper highlights the work conducted by the Clemson Cooperative Extension Service, in partnership with organizations across South Carolina, to adapt and deliver the Health Extension for Diabetes program to the Hispanic community. It offers insights into effective strategies for program adaptation, recruitment, and delivery that agents can use to overcome barriers and increase …

Heterogeneous Graph-Augmented Contrastive Learning For Extreme Multi-Class Fiqh Classification, Ali A. Jalil

Al-Bahir

• Background/Introduction: Fine-grained text classification in the field of Islamic Jurisprudence (Fiqh) is difficult because of the structural interdependence of the legal concepts and the extremely multi-class long-tail data distribution (667 classes with 5,979 samples, 52.2% of which contain less than 5 samples). The main problem with traditional flat classifiers is that they assume that target classes are independent and orthogonal output neurons which discards very important relational semantics.
• Objectives: This paper seeks to remediate this extreme imbalance and maintain structural taxonomy by modeling the structural space of classification label space itself as an object to be learned, while giving a …

Sharing The Love: Using School Libraries As Support In Inquiry-Based Learning, Katrina Sanville

Information Literacy Collab

No abstract provided.

Full Issue, Information Literacy Collab

Information Literacy Collab

No abstract provided.

Editor's Note, Robert Rabe

Journal of 20th Century Media History

Editor's Note for Vol. 4, Issue 1 (2026)

Mental Health Challenges Associated With Social Media Use And Effective Management Strategies: A Systematic Literature Review, Ebrahim Timol, Kebashnee Moodley

The African Journal of Information Systems

This study conducts a Systematic Literature Review (SLR) to investigate the mental health challenges associated with increasing social media (SM) usage. The review compares these effects across youth and adult age groups and explores how mental health issues related to SM use have evolved before, during, and after the COVID-19 pandemic. Through a comprehensive search of databases including ProQuest, Scopus, JSTOR, and Google Scholar, 43 relevant articles were analyzed using thematic analysis. The findings reveal that social media usage exacerbates mental health issues such as depression, anxiety, fear of missing out (FOMO), social and financial comparisons. The COVID-19 pandemic notably …

Teachers’ Experiences In Teaching Foundational Reading Skills In The General Education English Language Arts Classroom In Grades 9-12, Jodi Leigh Mckenzie

Walden Dissertations and Doctoral Studies

No abstract provided.

Reframing The "Weekend Effect": From Hospital "Failure" To System-Level Selection, Jonathan Dawson, Aditya Loganathan, Nicholas Melucci, Michael Friedman, Maeve Mclaughlin, Marissa Potenza, Erica Valdovinos, Robert Shesser

URGENT Matters

No abstract provided.

Recommendations For Conducting Ethical Network Research, Francisca Ortiz Ruiz, Paola Tubaro, José Luis Molina, Jennifer Watling Neal, Raffaele Vacca, Jana Diesner, Jimi Adams, Michelle Birkett, Jenny Godley, Juniper Lovato, Michael Schönhuth, Laura Teves, Michael Zimmer

Faculty Publications

Ethical considerations in social network studies are grounded in the general principles of human subjects’ research, including avoidance of harm, promotion of justice, equitable distribution of burdens and benefits, respect for human dignity, and protection of confidentiality. To help navigate these challenges, this article presents recommendations for conducting ethical network research, developed by a multi-disciplinary and multi-national working group. The article is divided in three main sections where there are certain recommendations identified for each one of them: data collections, use, and availability. Discovering how others addressed and solved problems can be a way for all of us to improve …

Hypoglossal Nerve Stimulation For Obstructive Sleep Apnea: A Systematic Review And Meta-Analysis On Responder-Based Outcomes And Between-Study Heterogeneity, Clemens Heiser, Marcel Braun, Colin Huntley, Michael Hutz, Thomas Michael Kaffenberger, Maurits Boon

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

Background: Hypoglossal nerve stimulation (HNS) is an established surgical therapy for adults with moderate-to-severe obstructive sleep apnea (OSA) who are intolerant to positive airway pressure. Although aggregate response rates of ~70–80% have been reported, substantial variability across clinical settings remains poorly understood. Prior meta-analyses have largely emphasized pooled continuous outcomes, limiting interpretation of responder-based endpoints and drivers of between-study heterogeneity. Methods: A PRISMA-compliant systematic review and meta-analysis was performed. MEDLINE, Embase, and Cochrane CENTRAL were searched from inception through 31 December 2025. Eligible studies enrolled adults with OSA treated with implantable HNS, reported Sher-defined response (≥50% AHI reduction and residual …

Zoom In And Zoom Out: (Re)Telling Our Cultural Literacy Practices Through Engaged Learning, Isela Almaguer

Bilingual and Literacy Studies Faculty Publications

Empowering bilingual learners to engage in the Zoom In and Zoom Out approach is a way to enrich and validate students' cultural identity and support students' linguistic and academic development while fostering rich writing opportunities for students. Teachers will discover a genuine way that empowers students to explore vocabulary, build comprehension, and acquire a love for writing. This effective multifaceted strategy approaches writing by leveraging students' cultural background and literacy practices. Students will capitalize on their funds of knowledge and use their experiences to further propel their writing efforts. By starting from within, diverse learners make stronger connections with the …