Digital Commons Network^™

What Are Anomalies In A Network?, Kai Ming Ting, Zhong Zhuang, Guansong Pang, Zongyou Liu, Tianrun Liang, Qiuran Zhao

Research Collection School Of Computing and Information Systems

This article examines a collection of assumptions used in the current literature on node anomaly detection in a network. The examination raises the question: What are anomalies in a network? Our attempt to answer this question has provided some interesting findings and led to some open questions. This is the first article which formally defines anomalies in a network and introduces the concept of self-verifiability of a detector without ground-truths in a network. They enable existing detectors to be categorized into two types along the line whether they are self-verifiable or not. We suggest a method to evaluate self-verifiable detectors …

Singapore At 60: Home Truly Is An Idea That Never Stands Still, Lily Kong

Research Collection School of Social Sciences

There are many new stories to embrace but also quiet distances between us that we must bridge.

In a National Day op-ed published in The Straits Times, SMU President Professor Lily Kong reflects on what ‘home’ means as Singapore marks its 60th year of independence — and how that meaning continues to evolve across generations. Prompted by a walk through a familiar playground now transformed, Prof Kong considers how Singapore’s changing physical and social landscape mirrors shifts in national identity. While progress and policy evolution signal a society in transition, she also notes the emergence of quieter divides – between …

Diaspora By Another Name: The Making Of Refugees In Cold War China, Jiaqi M. Liu, Clare Xiaoqian Wan

Research Collection School of Social Sciences

By examining China’s refugee policies from 1949 to 1982, this article demonstrates how the Chinese state redefined “return” and “refugee” to serve shifting political objectives. While China is often perceived as a source, rather than a host, of asylum seekers, it hosted over 320,000 displaced migrants—primarily ethnic Chinese from Southeast Asia—during the Cold War. Through a systematic discourse analysis of 382 People’s Daily articles, we identify four state narratives—diaspora, diplomatic tool, ideological sanctuary, and legal duty—that structured how China labeled displaced migrants, interpreted their sentiments, and determined their settlement. These models evolved dynamically: from the 1950s to the late 1970s, …

Not Staying Regular?, Joshua Thong

Research Collection School of Social Sciences

Consider the following claims: 1. Rational credences are real-valued. 2. A rational agent is more confident in than in just in case appropriate set-theoretic relations between the relevant events and/or appropriate inequalities between her numerical credences, whether conditional or not, hold. 3. If a rational agent’s conditional credence in, given, is greater than her conditional credence in, given, then she is more confident in than in. 4. There are two distinct and particular ways of ordering the events in a lottery over the naturals, for each of which there exists a rational agent whose comparative confidence ordering corresponds to that …

Calibrated Structures Of Feeling: Cultural Citizenship And The Reproduction Of The Military In Singapore, John Lowe, George Wong

Research Collection School of Social Sciences

This article discusses the nexus between Raymond Williams’ structure of feelings and the reproduction of military masculinity as cultural citizenship. By placing the gaze upon National Service in the Singapore Armed Forces as a rite of passage into manhood, this work uses representations of the military in popular culture and souvenirs/ephemera to elucidate how structures of feeling are calibrated as masculinity the state wants its citizenry to internalize. These render military masculinity emergent for Singaporean male bodies. With the male body functioning as an important edifice of the military, emotions toward military service are the connective tissue between enactments of …

Governing Migration, Producing Skills: Emigration And Education In The Philippines, Yasmin Y. Ortiga, Roderick. Galam

Research Collection School of Social Sciences

This article examines skill as an integral yet understudied aspect of emigration governance. To date, migration studies have mainly focused on how the demand for migrant skills drive people's movements across borders, shaping the conditions for entry into popular destinations in the West. In contrast, less is known as to how skills also shape the way governments manage emigration, pushing would-be migrants to acquire certain capacities well before they leave their countries of origin. Drawing from the case of the Philippines, this article discusses how state agencies have used skills training to dominate specific markets for migrant professionals and demand …

Stockpiling, Forecasting And Protecting Skills: Skilling As Technique Of Preparedness In Times Of Crises, Rebecca Ye, Yasmin Y. Ortiga

Research Collection School of Social Sciences

In this comparative and situational analysis, we examine how nation-states use skilling as a technique of preparedness during crisis moments. By analysing two strategically selected country cases, Singapore and Sweden, during a critical phase of a global pandemic, we identify three techniques: stockpiling, forecasting, and protecting skills, and how these were enacted as a means to perform preparedness. Stockpiling skills was observed to take place as a rapid response; forecasting skills was a technique enacted with a view on the longer-term horizon and protecting skills was mobilised as a short-term future technique, where boundaries were assembled around skilling. While there …

Religious Beliefs, Cooperation, And Evolutionary Mechanisms, Nicole Fellice Ko, Norman P. Li

Research Collection School of Social Sciences

Religion is an organized system of spiritual beliefs, practices, and rituals that often involve a sense of the divine (Schilbrack, 2022). An evolutionary mechanism is an evolved set of traits that interpret environmental inputs and generate behavioral responses that enhance survival or reproductive success (Li et al., 2018). Cooperation refers to the act of individuals or groups working together to achieve a shared goal or mutual benefit (Alós-Ferrer & Garagnani, 2020).

The Role Of Private Law In Promoting Building Safety: The Case Of Singapore, Edward S. W. Ti

Research Collection Yong Pung How School Of Law

Singapore is a tiny granite rock situated just north of the equator. Lacking land, and indeed any kind of natural resource, means that the trend for urban development in the city-state will always be densifi cation; 96 per cent of residents in Singapore already live in multi-owned housing, ie high-rise apartments. 1 Singapore is also a rapidly greying nation. 2 It has been observed that persons over 70 years old are four times more vulnerable in the event of a fi re, 3 and fi re safety is a critical aspect of building safety. Safety features and measures in the …

Sensor Lag Adjustments On A Mobile Meteorological Cart In Tropical Environments: A Case Study From An Urban Park In Singapore, Moshe Eliezer Mandelmilch, Sin Kang Yik, Beatrice H. Ho, Graces N. Y. Ching, Peter J. Crank, Winston T. L. Chow

Research Collection College of Integrative Studies

This study adds to the growing literature on mobile platforms by examining the performance of the Singapore MaRTy (SMaRTy) in conducting mobile micrometeorological measurements along a designated route in an urban park in Singapore, reflecting a pedestrian walking experience. The main objective of the study was to calculate the sensor lag for the mobile climate measurements: Air Temperature (TA), and Relative Humidity (RH) of SMaRTy along a designated route in an urban park in Singapore based on data from fixed stations (HOBO sensors) in two significant synoptic meteorological periods during the Northeast and Southwest monsoons. Statistically significant regression models were …

The Miseducation Of Model Minorities: The Gospel Of ‘Schoolvation’ And The Myth Of The Schooled Society, Justin Kh Tse

Research Collection College of Integrative Studies

The ‘model minority’, the phenomenon of some ‘minority’ communities (or some members within them) achieving social and economic advancement despite encountering the difficulties of assimilating into a mainstream society, is often described as a myth, especially as one of the central problematics in Asian American studies. Usually, the modern use of the word myth is pejorative: the model minority in this sense refers to a false empirical description of some minorities and should be quantitatively disaggregated and qualitatively debunked. In this article, I want to explore the model minority as another kind of myth, in the classical sense of mythos, …

Do Supplier Ceo's National Cultural Origins Affect Supplier-Customer Relationships?, Peng Liang, Hasan Cavusoglu, Nan Hu

Research Collection School Of Computing and Information Systems

This study investigates how the national cultural origins of supplier chief executive officers (CEOs), as characterized by Hofstede’s cross-cultural dimensions, influence the duration of supplier–customer relationships. By analyzing the cultural origins of supplier CEOs from 20 countries over a 25-year period, we find that supplier CEOs with high long-term orientation (LTO) and high uncertainty avoidance (UNA) are associated with longer lasting supplier–customer relationships, while those with high individualism (IND) are associated with shorter relationship durations. These findings are robust to several alternative explanations of customer and supplier CEO variables. To address potential endogeneity—specifically, the concern that CEOs with certain cultural …

Oatp1b1/1b3 Deficiency Exacerbates Hyperbilirubinemia In Erythropoietic Protoporphyria, Ruizhi Gu, Fu-Ying Qin, Luxuan Wang, Jiaojiao Zhang, Jacob Emerson, Qing Ma, Jie Lu, Karl E Anderson, Junmei Wang, Xiaochao Ma

Faculty, Staff and Student Publications

Erythropoietic protoporphyria (EPP) is caused by loss-of-function mutations in ferrochelatase (FECH), leading to the accumulation of its substrate, protoporphyrin IX (PPIX). PPIX is primarily produced in the bone marrow and transported to the liver for excretion. Because PPIX is hydrophobic, its elevated levels can cause bile duct blockage, cholestatic liver injury, and even liver failure. However, the specific transporter responsible for PPIX uptake into hepatocytes remains unclear. The OATP1B1/1B3 transporters, which are expressed in hepatocytes, facilitate the uptake of coproporphyrin III, a structural analog of PPIX. Additionally, OATP1B1/1B3 mediates the uptake of bilirubin, a biomarker of liver injury, from plasma …

Outcomes And Toxicity Following 3 Or More Definitive Courses Of Thoracic Radiation Therapy For Non-Small Cell Lung Cancer, Abigael Odwuor, Percy Lee, Joe Y Chang, Saumil Gandhi, Zhongxing Liao, Steven H Lin, Aileen Chen, Quynh-Nhu Nguyen, Michael S O'Reilly, Stephen G Chun, Julianna Bronk, David Qian, Matthew S Ning

Faculty, Staff and Student Publications

Purpose: Salvage re-irradiation is increasingly utilized to manage non-small cell lung cancer (NSCLC) locoregional recurrence or new lung primaries in previously treated areas. There is sparse information on efficacy and toxicity profile. We report a large experience of patients treated with multiple courses of definitive radiation for new and recurrent NSCLC.

Methods and materials: Medical records of patients who underwent ≥ 3 definitive thoracic radiation therapy (RT) courses for new or recurrent NSCLC at our cancer center from 2012 through 2021 were retrospectively reviewed following institutional review board approval. Toxicity was graded per Common Terminology Criteria for Adverse Events (CTCAE) …

Heat Shock Induces Alternative Polyadenylation Through Dynamic Dna Methylation And Chromatin Looping, Emily E Fink, Yi Zhang, Briana Santo, Anwita Siddavatam, Rosie Ou, Vishal Nanavaty, Byron H Lee, Angela H Ting

Faculty, Staff and Student Publications

Alternative cleavage and polyadenylation (APA) is a gene regulatory mechanism used by cells under stress to upregulate proteostasis-promoting transcripts, but how cells achieve this remains poorly understood. Previously, we elucidated a DNA methylation-regulated APA mechanism, in which gene body DNA methylation enhances distal poly(A) isoform expression by blocking CCCTC-binding factor (CTCF) binding and chromatin loop formation at APA control regions. We hypothesized that DNA methylation-regulated APA is one mechanism cells employ to induce proteostasis-promoting poly(A) isoforms. At the DNAJB6 cochaperone locus, acute heat shock resulted in binding of stress response transcription factors heat shock factor 1, ATF6, and YY1 at …

Ovarian Cancer Risk And Survival According To Tumor Sex Hormone Receptor Expression: An Ovarian Cancer Association Consortium And Ovarian Tumor Tissue Analysis Consortium Pooled Analysis, Zhuxuan Fu, Lauren Borho, Sarah E Taylor, Linda E Kelemen, Anna Defazio, Penelope M Webb, Martin Köbel, Nicola S Meagher, Renhua Na, Antonis C Antoniou, Alison H Brand, Catherine J Kennedy, Nikilyn Nevins, Paul D P Pharoah, Yurii B Shvetsov, Stacey J Winham, Jennifer Alsop, Matthias W Beckmann, Adelyn Bolithon, Jessica Boros, David D L Bowtell, James D Brenton, Michael E Carney, Anita Chudecka-Głaz, Linda S Cook, Cezary Cybulski, Peter A Fasching, Sian Fereday, Renée T Fortner, María J García, Ellen L Goode, Marc T Goodman, Jacek Gronwald, Arndt Hartmann, Brenda Y Hernandez, Estrid Høgdall, David G Huntsman, Allan Jensen, Mercedes Jimenez-Linan, Janine M Joseph, Beth Y Karlan, Ewa Kaznowska, Susanne K Kjaer, Tomasz Kluz, Jennifer M Koziak, Jenny Lester, Teri A Longacre, Maria Lycke, Valerie Mcguire, Kirsten B Moysich, Rachel A Murphy, Sandra Orsulic, Susan J Ramus, Cristina Rodríguez-Antona, Joseph H Rothstein, Spinder Samra, Weiva Sieh, Helen Steed, Karin Sundfeldt, Aline Talhouk, Jan Uciński, Chen Wang, Nicolas Wentzensen, Alice S Whittemore, Lynne R Wilkens, Thomas Songer, Maria Mori Brooks, Lu Tang, Francesmary Modugno

Faculty, Staff and Student Publications

Objective: Many epithelial ovarian cancer (EOC) risk factors relate to sex hormones. The association between these factors and the expression of androgen receptor (AR), estrogen receptor-α (ER), and progesterone receptor (PR) in tumors is unknown.

Method: We linked epidemiologic, AR/ER/PR tumor expression, and survival data from 19 studies in the Ovarian Cancer Association Consortium (OCAC; 4762 cases, 20,888 controls) and the Ovarian Tumor Tissue Analysis (OTTA) consortium (5737 cases). We estimated odds ratios (ORs) and 95 % confidence intervals (CIs) between hormonally-linked factors and tumor AR/ER/PR expression using polytomous logistic regression. We assessed survival by AR/ER/PR tumor expression overall and …

Renal G Protein-Coupled Estrogen Receptor 1 Regulates The Epithelial Sodium Channel Promoting Natriuresis To A Greater Extent In Females, Victoria L Nasci, Jean C Bopassa, Elena Mironova, Megan Rhoads, Ravneet Singh, Dennis P Buehler, David M Pollock, Oleh M Pochynyuk, James D Stockand, Eman Y Gohar

Faculty, Staff and Student Publications

Hypertension prevalence is lower in women than men. Enhanced renal sodium (Na+) handling in females has been implicated in sex-differences in hypertension. Epithelial Na+ channel (ENaC) is a key contributor to Na+ homeostasis and is regulated by estrogen. Recent evidence suggests G protein-coupled estrogen receptor 1 (GPER1) evokes a female-specific natriuresis that involves endothelin-1 (ET-1). ET-1 has been shown to downregulate ENaC activity, but whether GPER1 regulates ENaC to modulate natriuresis is unknown. We tested the hypothesis that renal GPER1 functionally interacts with ENaC to promote natriuresis in a sex-specific manner. RNAscope confirmed co-expression of GPER1 and ENaC in rat …

Childhood Obesity Body Mass Index And Gut Microbiome: A Cluster Randomized Controlled Pilot Feasibility Study, Marilyn Frenn, Nita Salzman, Vy Lam, Mary Holtz, Andrea Moosreiner, Mauricio Garnier-Villarreal, Maharaj Singh

College of Nursing Faculty Research and Publications

Background:

Prebiotic fiber has been examined as a way to foster gut bacteria less associated with obesity. Tests of prebiotic fiber in reducing obesity have occurred mainly in animals, adults, and Caucasians when the highest obesity rates are in African American and Latinx youth. Response to prebiotic fiber is determined by the pre-existing intestinal microbiota. The type of microbiota varies based on diet and physical activity (PA), so it is important to examine acceptability and response to prebiotic fiber in those most at risk for obesity.

Methods:

This cluster randomized controlled feasibility trial included an online program designed to improve …

Exploring The Clinical Utility Of Neurofilament Light Chain Assays In Multiple Sclerosis Management., Amit Bar-Or, Jacqueline Nicholas, Jenny Feng, Francesca Sorrell, Mark Cascione

Neuroscience Articles

Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease that affects nearly 1 million adults in the United States. Owing to its unpredictable disease course, diverse phenotypes, and an array of currently available disease-modifying therapies, a personalized approach to MS management is required. There is an unmet need to identify, validate, and incorporate prognostic, monitoring, and predictive biomarkers into routine clinical practice for MS. A mounting body of evidence supports the use of blood biomarkers, such as neurofilament light chain (NfL), in predicting disease activity and monitoring treatment response. Previous hurdles for the widespread use of NfL in the …

An Exploration Of Students' Recollections After An Asynchronous, On-Site Academic Library Tour, Adrienne Warner

University Libraries & Learning Sciences Faculty and Staff Publications

Once an integral component to library instruction programs, tours of academic library spaces are less common despite students’ continued need for study spaces with various qualities. This study asks, "What do students remember after taking an asynchronous, on-site academic library tour?" Qualitative analysis finds that, while students value library study spaces, they also report predominantly positive feelings about the library and the tour itself. This research suggests that technical affordances can mitigate some historical drawbacks of tours while offering students a valuable library instruction experience.

From Nation-Building To Collapse: Analyzing Afghanistan’S 2021 Fall And The Geopolitical Entropies Of U.S. Withdrawal, Arash Beidollahkhani, Edriss Rasa

Journal of Strategic Security

The collapse of the Afghan government in 2021 and the subsequent return of the Taliban marked a significant shift in contemporary geopolitics. This paper examines the political and social dynamics surrounding the U.S. and allied forces' withdrawal, focusing on the entropic forces that contributed to the breakdown of Afghanistan’s governance system. While Afghanistan has experienced recurrent governmental collapses, the post-2021 crisis highlights deeper structural challenges within both the geopolitical and domestic spheres. The research investigates the failure of the U.S.-backed Afghan government, established through two decades of nation-building efforts, and explores how the abrupt foreign withdrawal dismantled fragile political structures, …

Taliban 1.0 And 2.0 In Afghanistan: Same Policies, Persistent Vision, Sharif Hozoori

Journal of Strategic Security

The Taliban emerged as a movement in 1994, toppled the government of the Mujahideen, and ruled Afghanistan from 1996 to 2001. They finally recaptured power in 2021 after the US withdrawal from the region. This paper refers to the first Taliban rule as Taliban 1.0 and their second as Taliban 2.0. Taliban 1.0 imposed draconian laws and regulations on women and minorities while harboring regional and international terrorist organizations. Later, the Taliban 2.0 followed its predecessor in policies regarding women, minorities, and sheltering terrorist organizations. Considering this background, this paper addresses whether Taliban 1.0 and 2.0 maintain the same policies …

A Descriptive Bibliometric Study Of Cera Publication Dissemination, Authorship, And Citation Rates., Bryce A Ringwald, Jennifer L Middleton

Medical Education Articles

BACKGROUND AND OBJECTIVES: Barriers to performing family medicine research include funding, infrastructure, and mentorship shortages. The Council of Academic Family Medicine Educational Research Alliance (CERA) was created in 2011 to address these issues. This study explores the scope and impact of CERA-related publications in family medicine.

METHODS: We performed a descriptive bibliometric study of CERA-related publications from 2011 to 2023. Articles were sourced from Medline (PubMed), SCOPUS, and the CERA website. Data analysis focused on publication type, authors, CERA survey type, and citation rates.

RESULTS: From a total of 231 articles retrieved via initial searches and 166 from the CERA …

Statewide Injunction: State Judicial Power And Meaningful Remedies, Constance C. Van Kley

Faculty Law Review Articles

As federal courts increasingly limit the scope of constitutional remedies, state courts have begun issuing statewide injunctions that extend protections beyond individual litigants. This article examines the doctrinal foundations and implications of such injunctions, arguing that they represent a legitimate exercise of state judicial power. By analyzing historical practices, procedural norms, and recent case law, the author contends that statewide injunctions can serve as essential tools for enforcing civil rights and ensuring meaningful relief. The piece calls for a reevaluation of remedial doctrines to better accommodate the evolving role of state courts in safeguarding constitutional guarantees.

Chronic Pain Is Associated With Greater Brain Entropy In The Prefrontal Cortex, Gianpaolo Del Mauro, Yiran Li, Jiaao Yu, Peter Kochunov, Landrew Samuel Sevel, Jeff Boissoneault, Shuo Chen, Ze Wang

Faculty, Staff and Student Publications

Chronic pain is a debilitating clinical condition and a severe public health issue that demands to be addressed. Neuroimaging-based techniques have been widely adopted to investigate the neural underpinnings of chronic pain. Despite the efforts the complex nature of pain experience as well as the heterogeneity of chronic pain have made the identification of neuroimaging-based biomarkers extremely challenging. In this study, resting-state fMRI-based brain entropy, a measure reflecting the "irregularity" of brain activity, was adopted as a biomarker of chronic pain by comparing individuals with chronic pain and healthy controls in a sample of middle-to-old-age participants (n > 30,000) drawn from …

Exploring The Efficacy Of Various Minimally Invasive Surgery (Mis) Techniques In Spinal Fusion For Degenerative Spondylolisthesis: A Systematic Review, Yolanda V. Gutierrez, Blake Martin, Joshua Nwose, Alyssa A. Sepulveda, Ronald Shaju, Aamir Ahmad, Robert H. Ablove

School of Medicine Publications

Degenerative spondylolisthesis is a common etiology of low back pain characterized by the anterior displacement of one vertebral body relative to the one below it. A key contributing factor is intervertebral disc degeneration, which compromises spinal stability. In patients with a lack of neurological issues, conservative treatment is recommended. If conservative treatment is ineffective, surgery is deemed the next step, involving decompression and fusion of the vertebrae. Over the past several decades, minimally invasive surgical (MIS) techniques have been developed and refined. This systematic review aims to compare different types of MIS techniques for the treatment of degenerative spondylolisthesis to …

Asthma Exacerbation: Dexamethasone Vs. Prednisolone Dosing, Children's Mercy Kansas City

Clinical Critically Appraised Topics

No abstract provided.

Cell-Free Protein Synthesis Reactor Formats: A Brief History And Analysis, Dallin M. Chipman, Anna C. Woolley, Davu N. Chau, William A. Lance, Joseph P. Talley, Tyler P. Green, Benjamin C. Robbins, Bradley Charles Bundy

Faculty Publications

Cell-free protein synthesis (CFPS) has transformed protein production capabilities by eliminating cellular constraints, enabling the rapid expression of difficult-to-produce proteins in an open, customizable environment. As CFPS applications expand from fundamental research to industrial production, therapeutic manufacturing, and point-of-care diagnostics, the diverse array of reactor formats has become increasingly important yet challenging to navigate. This review examines the evolution and characteristics of thirteen major CFPS reactor formats, from traditional batch systems to advanced platforms. The historical development of CFPS reactors from the 1960s to present day is presented. Additionally, for each format, operational principles, advantages, limitations, and notable applications are …

A Systematic Review Of The Internet Of Things And Artificial Intelligence Applications In Milk Quality Monitoring And Analysis, Rahul Mhapsekar, Deirdre Kilbane, Steven Davy, Lizy Abraham, Mark Fenelon, Norah O'Shea

Research Outputs: 2025-Present

Background: Milk quality analysis (MQA) is critical for ensuring high-quality dairy production and enhancing the productivity of dairy processing plants. The integration of Internet of Things (IoT) and artificial intelligence (AI) can revolutionise MQA by enabling automated, real-time detection and monitoring of key parameters (i.e. composition, adulterants, indicators of microbial quality), reducing human error and improving decision-making in the dairy supply chain. Aim(s): This systematic review aimed to evaluate the application of IoT and AI in MQA over the past decade, focussing on three critical areas: composition monitoring, adulteration detection and indicators of microbial quality. Methods: A systematic analysis of …

Volume 34, Number 2, Summer/Fall 2025, Office Of Communications, Illinois Wesleyan University

Illinois Wesleyan University Magazine, 2018-present

VOLUME 34 | NUMBER 2 | Summer/Fall 2025

ON OUR COVER:

The Illinois Wesleyan University archives, housed on the fourth floor of The Ames Library, holds many artifacts of IWU history, including the original university charter and a gold medal awarded to John Marden, clas of 1909, for his breakthrough work in atomic science and engineering.

18 175 Years of Illinois Wesleyan University. Celebrate IWU's history with a timeline of the last 175 years of our community's milestones.

26 Alumni Award Winners. Meet our Award Winners John Camardella '03, Natalie Lalagos '12, and Carol Willis '68.