Digital Commons Network^™

Targeting Sting To Disrupt Macrophage-Mediated Adhesion In Encapsulating Peritoneal Sclerosis, Juan Sun, Yuxiang Sun, Dandan Guo, Huolin Ye, Qiang Huang, Hu Zhou, Canming Li, Mei Liao, Yujia You, Hongli Shang, Pan Zhou, Dongxuan Wu, Janusz Witowski, Zhaoyong Hu, Hui Peng

Faculty, Staff and Students Publications

Encapsulating peritoneal sclerosis (EPS) is a life-threatening fibrotic condition characterized by severe abdominal adhesions, chronic inflammation, and significant morbidity. The lack of effective treatments for EPS stems from a limited understanding of its underlying mechanisms. In this study, we developed a modified mouse model of PD-induced EPS and investigated the role of the STING signaling pathway in disease progression. Our findings reveal that STING activation in peritoneal mesothelial cells significantly increases the secretion of the macrophage chemokine CCL2, leading to enhanced macrophage infiltration and the formation of pathological adhesions. Notably, pharmacological inhibition of STING using the inhibitor H151 effectively reduced …

Applying Contextual Behavioral Science To Address Addictions In Monsters, Chase Hollander

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

The dominant essentialist paradigm in addiction treatment often conceptualizes addiction as a curse or plague which seizes the individual afflicted by it. Such views are reinforced by neurobiological interventions like Medication-Assisted Treatment (MAT). While MAT can reduce cravings and withdrawal symptoms, its long-term efficacy is mixed, and its emphasis on abstinence as a primary outcome limits its scope. Addiction is a multifaceted phenomenon shaped by physiological, psychological, social, and systemic factors—including stigma, moral judgment, and structural oppression. Essentialist approaches frequently pathologize individuals and obscure these broader influences. In contrast, contextual behavioral sciences and therapies aligned with functional contextualism such as …

Recruiting, Retaining, And Culturally Sustaining Latine Teachers In A School District With A High Population Of Latine Students, Lisa Garcia Simms

Electronic Theses and Dissertations

Latine students make up 52% of the Denver Public Schools (DPS) population, yet only 23% of its teaching force is Latine. This imbalance has real implications for student experience and opportunity. In 2024, DPS commissioned the La Raza Report, which detailed challenges faced by Latine students and educators and called for systemic improvements. The findings highlighted a clear need to strengthen recruitment, retention, and culturally sustaining support for Latine educators.

This improvement science project investigated how DPS might improve the experiences of Latine teachers—engaging educators across career stages, with a particular focus on supporting early-career Latine teachers —through identity-affirming mentorship …

Surgeon Ergonomics While Performing Total Knee Arthroplasty, Cameron Dahman

Electronic Theses and Dissertations

One of the most prevalent hazards to orthopedic surgeons are musculoskeletal disorders with 97% of arthroplasty surgeons reporting procedural-related musculoskeletal pain and 66% of orthopedic surgeons reporting procedural-related musculoskeletal injury [1], [2], [3]. With the annual number of total knee arthroplasties (TKA) on the rise, orthopedic surgeons are taking on larger annual caseloads and retiring later in life [4], [5]. The goal of this study was to quantify postural demand for 11 discrete surgical steps of TKA to identify ergonomically unfavorable positions surgeons experience while operating. Four orthopedic surgeons performed TKA while their motions were recorded using marker-based motion capture. …

Influence Of Obesity On Knee Joint Mechanics: A Subject-Specific Musculoskeletal Modeling Approach, Ryan C. Knowles

Electronic Theses and Dissertations

Obesity has been consistently linked to knee osteoarthritis (KOA), a debilitating joint disease. While prior work has shown that obese individuals often walk with altered biomechanics compared to normal-weight (NW) individuals, which may accelerate KOA progression, less is known about how these mechanics affect load distribution between the medial and lateral tibiofemoral (TF) compartments, particularly during higher-demand activities. This study developed subject-specific musculoskeletal models of five obese and five NW individuals, incorporating CT-based bone measurements and individualized joint contact points. Simulations were driven by six degree-of-freedom (6DOF) kinematics obtained from high-speed stereo radiography (HSSR) to predict TF loading and associated …

Exhibiting Rural Consciousness: A Study Of State And Local Level Governance In Rural Higher Education, Steven J. Skadron

Electronic Theses and Dissertations

Evolving economies in Craig and Salida, CO, spurred community interest in joining Colorado Mountain College’s taxing district and bringing the college to their communities. When they sought to join, Craig had a local college embedded in its community that was governed by a state-level board; in contrast, Salida had no local college of its own. The two communities’ pursuit of a locally governed college raised a question about governing boards and whether one type of governing board might serve rural communities better. Using a framework of rural consciousness, this nonexperimental, cross-sectional, quantitative study employed data gathered from a survey instrument …

Examining Whiteness: A Narrative Inquiry Into Racial Identity Among White Women In Study Abroad Programs, Audrey Moreno Townsend

Electronic Theses and Dissertations

The purpose of this narrative inquiry study was to better understand race in contexts both domestically and abroad through the perspectives and experiences of white women who studied abroad outside of Europe and the Anglosphere. The investigation explored on how these experiences shaped white women’s understanding of racial identity upon returning to their home institutions. The research question which was addressed was: How do white women experience study abroad programming? Research highlights a critical gap in existing literature on this topic. While white women are centered in the study, it is contextualized considering how People of Color experience the world. …

Prolonged Exposure To Food Odors Suppresses Feeding Via An Olfactory Bulb-To-Hypothalamus Circuit, Yao Liu, Hailan Liu, Huey-Xian Kelly Wong, Niccole Auld, Kristine M Conde, Yongxiang Li, Meng Yu, Yue Deng, Qingzhuo Liu, Xing Fang, Mengjie Wang, Yuhan Shi, Olivia Z Ginnard, Yuxue Yang, Longlong Tu, Hesong Liu, Jonathan C Bean, Junying Han, Megan E Burt, Sanika V Jossy, Yongjie Yang, Chunmei Wang, Qingchun Tong, Benjamin R Arenkiel, Hongjie Li, Yong Xu, Yang He

The Brown Foundation: Institute of Molecular Medicine

Olfactory perception of food odors is a key determinant of eating behavior, including triggering appetite, facilitating food seeking and influencing food choice. While transient food-related olfactory cues stimulate appetite and provoke cravings in states of hunger, emerging evidence implies that prolonged and sustained exposure to food-derived odor (FO) suppresses feeding. However, the mechanisms by which olfaction induces hypophagia remain elusive. In this study, we show that prolonged FO exposure significantly suppresses food intake in male mice. We identified a subset of neurons in the ventral subiculum (vSub) that are specifically activated by FO. We further discovered that these FO-activated neurons …

The Developmental Cohort Model Of Interpersonal Process Groups: A Clinician's Guide For University Counseling Centers, Lauren Caldas

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

The purpose of this paper is to outline a clinician's manual that guides providers in the development, facilitation, and maintenance of long-term interpersonal process groups (IPGs) within university counseling centers (UCCs). This manual also presents a new model: The Developmental Cohort Model (DCM), which utilizes a stepped model throughout a traditional student's college timeline. I will present this manual in the context of the Developmental Cohort Model (DCM), but it can certainly remain useful for any type of IPG. Research suggests that group therapy is an effective way to increase access to mental health care (Burlingame & Strauss, 2021) and …

A Clinical Pathway For Differential Diagnosis Of Adhd Vs Trauma: Early Childhood Recognition And Intervention, Maria Neiers

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Distinguishing Attention-Deficit/Hyperactivity Disorder (ADHD) from Complex Posttraumatic Stress Disorder (C-PTSD) presents significant diagnostic challenges due to overlapping symptom presentations, shared neurobiological impacts, and frequent comorbidities. This paper explores the nuanced clinical differentiation between ADHD and C-PTSD, and other trauma disorders, in pediatric populations, emphasizing the importance of trauma-informed assessment, early identification, and integrative clinical reasoning. The discussion highlights how structured diagnostic reasoning can reduce uncertainty, enhance diagnostic clarity, and support effective treatment planning. As a central contribution, this paper introduces an original clinical reasoning flowchart and a case conceptualization to illustrate its practical application in real-world diagnostic dilemmas. The need …

The Journey Of Psychotherapy: Understanding Therapeutic Technique Through Ultralight Thru Hiking, Emma Bossier

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

This paper explores several principles of ultralight backpacking as metaphors for developing one’s therapeutic technique. The tenets of ultralight thru hiking, when interpreted through a clinical lens, offer early clinicians insight into the importance of moving through fear and leaning into exploration, discomfort, and authenticity while on the journey of becoming a therapist. The experiences of numerous thru hikers are synthesized into five principles: Don’t Pack Your Fears, Be Present for the Journey, Slow Simplicity, Embrace the Suck (and The Stink), and Trail Legs. These principles do not define ultralight as carefreeness but rather offer a metaphor for the careful …

There Is No Finish Line: The Ramps Framework – An Evolving Model For Working With Racial Identities In Sport And Performance Psychology, Dylan Vas

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

The field of sport psychology has persisted in its calls for action on increasing cultural competence, being more inclusive of underrepresented identities, and progressing towards social justice (AASP, 2024b; Bejar et al., 2022; Fisher et al., 2003; Martens et al., 2000; Quartiroli, et al., 2023; Ryba et al, 2013; Ryba et al., 2024). This work attempts to contribute to these calls by providing attention on racial identity – including the proposal of an actionable and novel model, The Racial Identity Model of Psychology in Sport (RAMPS) Framework. The proposed model incorporates publications from sport psychology, clinical psychology, and social justice …

The Lived Experience Of Filipino Nurses Caring For Patients With Covid-19, Kristeline Suasin

Creating Healthy Work Environments (CHWE)

Reports of individuals exhibiting respiratory symptoms causing sudden deaths emerged as a pandemic in the start of a new decade. The onset of the novel Coronavirus Disease 2019 (COVID-19) as a worldwide health crisis brought out the significance of the nurses’ role in healthcare. This descriptive phenomenological research focused on the caring experiences of Filipino nurses among patients who were infected with COVID-19 in Negros Oriental, Philippines. Seven participants were identified through purposive and snowball sampling and were asked the question: What is it like to be caring for patients diagnosed with COVID-19 in Negros Oriental, Philippines during this pandemic? …

Path Analysis Of Filipino Nurses' Intent To Stay In The United Kingdom, Blaise B. Nieve, Sarah Bernadette L. Baleña

Creating Healthy Work Environments (CHWE)

Nature and Scope. Nurse attrition remains a significant issue in the UK, particularly among Filipino nurses, who form a substantial portion of the healthcare workforce.

Research Method. This descriptive-correlational study utilized path analysis to identify the best-fit model for predicting the intent to stay among Filipino nurses in the UK, based on job embeddedness, sociocultural adaptation, and job satisfaction. Purposive sampling was employed to recruit 553 respondents, all of whom were Filipino nurses of legal age, qualified to practice in the UK, and employed as registered nurses for at least one year in the public or private sector. Data were …

Enhancing Cataract Surgery Outcomes: Optimal Use Of Pre- And Post-Operative Eye Drops, Keith Skolnick M.D., Anu Valiaveedu

Mako: NSU Undergraduate Student Journal

Many preoperative and postoperative cataract patients struggle with comprehending the use of prescription medication as directed. Language barriers and low health literacy levels are major factors contributing to improper use of prescriptions. To increase patients comprehension, the Fort Lauderdale Eye Institute employed an educational intervention consisting of a live presentation and an instructional video. Results found that 44% of patients were hesitant to ask questions to clinical staff, 32% felt overwhelmed, and nearly 70% lacked confidence in using their prescribed eye drops. Following the intervention, 91% of patients reported increased confidence in their medications, and most indicated that the video …

2025 Ursinus College Academic Convocation Program, Ursinus College

Academic Convocation Programs

This Ursinus College Academic Convocation program lists speakers and events for the opening of the 2025 academic year.

Maya Binyam, Raymond Carver Reading Series, February 12, 2025, Maya Binyam

Raymond Carver Reading Series

A video recording of Maya Binyam reading on February 12, 2025, as part of the Syracuse University Creative Writing Program's Raymond Carver Reading Series.

Hari Kunzru, Raymond Carver Reading Series, March 19, 2025, Hari Kunzro

Raymond Carver Reading Series

A video recording of Hari Kunzro reading on February 26, 2025, as part of the Syracuse University Creative Writing Program's Raymond Carver Reading Series.

Hayan Charara, Raymond Carver Reading Series, April 2, 2025, Hayan Charara

Raymond Carver Reading Series

A video recording of Hayan Charara reading on April 2, 2025, as part of the Syracuse University Creative Writing Program's Raymond Carver Reading Series.

Claire Messud, Raymond Carver Reading Series, April 23, 2025, Claire Messud

Raymond Carver Reading Series

A video recording of Claire Messud reading on April 2, 2025, as part of the Syracuse University Creative Writing Program's Raymond Carver Reading Series.

Natalie Shapero, Raymond Carver Reading Series, January 29, 2024, Natalie Shapero

Raymond Carver Reading Series

A video recording of Natalie Shapero reading on January 29, 2025, as part of the Syracuse University Creative Writing Program's Raymond Carver Reading Series.

A 6-Month, Prospective Randomized Controlled Trial Of The Targeted Management (Team) Intervention Vs. Enhanced Treatment As Usual Among Ugandans At Risk For Stroke, Carla Conroy, Joy Yala, Christopher J. Burant, Shirley Moore, Martha Sajatovic

Faculty Scholarship

Background Among low and middle-income countries, especially in Sub-Saharan Africa, the stroke burden is severe, with increasing trends in stroke incidence, prevalence, and mortality. Aims This 6-month, prospective randomized controlled trial (RCT) compared a novel stroke risk reduction approach (TargetEd manAgeMent Intervention (TEAM)) vs. Enhanced Treatment as Usual (ETAU) in 247 Ugandans at risk for stroke. Methods Participants, enrolled across 3 Ugandan sites, were adults with high stroke risk. The primary outcome was a change in systolic blood pressure (SBP) from baseline to 6-month follow-up. Secondary outcomes included changes from baseline to 6 months on diastolic BP (DBP), serum lipids, …

2018-09-12 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2018-11-06 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2016-09-27 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2016-10-04 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2015-10-13 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2015-11-17 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

“Can You Hear Me?” Teacher Stories About State-Mandated Standardized Testing, Michele I. Shelton

Educational Studies Dissertations

This study strives to understand teacher perceptions as a meaningful examination of state-mandated standardized testing's impacts on students and its outcomes by asking:

How do teachers experience the impact of state-mandated standardized tests on the students as evidenced in their stories?

What are the benefits and disadvantages to the use of state-mandated standardized tests?

To what extent has state-mandated standardized tests created inequalities in the educational system?

This study utilized a Narrative Research approach with [descriptive] interpretive qualitative research. Questionnaires and interviews were analyzed using the Thematic Inductive Analysis approach. The theoretical framework was adopted from Robinson & Robinson: centering …

Profit Point Tax Technologies Inc V. Dpad Group Llp

2025 Decisions

USDC for the Western District of Pennsylvania