Digital Commons Network^™

Screening And Evaluation Of Thai Herbal Plants As Multifunctional Agents For Targeting Amyloid Β Pathogenesis In Alzheimer's Disease, Ruedeemars Yubolphan, Suchinda Malaivijitnond, Sukanya Jaroenporn

The Thai Journal of Pharmaceutical Sciences

Background: Alzheimer's disease (AD) is a neurodegenerative disorder driven by complex pathophysiological processes. Current therapeutic strategies emphasize the development of multifunctional agents, particularly those derived from natural sources, to target multiple stages of the amyloid β (Aβ) cascade, a central contributor to AD pathology.

Objectives: This study aimed to investigate the anti-Aβ activity of nine Thai herbs and evaluate their potential as multifunctional agents for AD treatment.

Methods: Nine Thai herbs—Caesalpinia sappan (CS), Thunbergia laurifolia (TL), Rhinacanthus nasutus (RN), Tabernaemontana divaricata (TD), Cyperus rotundus (CR), Terminalia chebula (TC), Azadirachta indica (AI), Piper retrofractum (PR), and Asparagus racemosus (AR)—were screened …

Free Speech At Colleges And Universities In The Mountain West, 2025, Olivia K. Cheche, Caitlin J. Saladino, William E. Brown Jr.

Higher Education

This fact sheet presents data on free speech at 16 colleges and universities across the Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah. The data are sourced from “The 2026 College Free Speech Rankings,” as originally published by The Foundation for Individual Rights and Expression (FIRE), and reflect 2025 data. The FIRE report presents free speech ranks, scores, grades, and data on speech controversies for 257 colleges and universities across 50 U.S. states and the District of Columbia. This fact sheet highlights the average free speech scores for each Mountain West state, as well as the free …

Rutabaga Cultivation In The Lake Superior Region, Russell Magnaghi

Upper Country: A Journal of the Lake Superior Region

The vast expanse of the Lake Superior Basin has been home to a multitude of industries from copper and iron mining, timber extraction, steel mills, grain transfer ports, and ship construction. However, given its northern location, agriculture is usually ignored due to a short growing season and poor soils. Immigrants who settled there like Finns and Scandinavians were familiar with this environment but even Italians found that they could develop their cherished home gardens and small farms. Most immigrants had migrated from farming environments and now accepted the challenge to farm in this new environment.

Of the many crops that …

The Student Movement Volume 110 Issue 1: Andrews Assembles For A New School Year, Megan Constantine, Kyle Simpson, Melanie Webb, Audrey Lim, Lia Glass, Corinna Bevier, Isa Demoraes, Nicholas Gunn, Reagan Westerman, Aiko J. Ayala Rios, Samantha Woolford-Hunt, Anna Rybachek, Maya Thomas, Andrew Francis

The Student Movement V. 110 (2025-2026)

HUMANS

Human Writer Introductions, Humans Writers

Becoming Disciple Makers: A Look Into Chaplain Fetrick's Vision for Andrews Unviersity, Megan Constantine

New at AU: Professor Carrie Hess, Kyle Simpson

ARTS & ENTERTAINMENT

Arts & Entertainment Writer Introductions, Arts & Entertainment Writers

Cut for Time: Recapping the 77th Emmy Awards, Melanie Webb

Team Conrad v. Team Jeremiah: The History and Appeal of Love Triangles in Media, Audrey Lim

The Summer of Superheroes, Lia Glass

Why I Hate the Trailer for the New 'Wutherinng Heights', Corinna Bevier

NEWS

News Writer Introduction, News Writers

Almost Anything Goes: A Night Lit in Neon, Isa DeMoraes …

Combined Annual Modulation Dark Matter Search With Cosine-100 And Anais-112, N Carlin, J Y Cho, J J Choi, S Choi, A C Ezeribe, L E França, C Ha, I S Hahn, S J Hollick, S B Hong, E J Jeon, H W Joo, W G Kang, M Kauer, B H Kim, H J Kim, J Kim, K W Kim, S H Kim, S K Kim, W K Kim, Y D Kim, Y H Kim, Y J Ko, D H Lee, E K Lee, H Lee, H S Lee, H Y Lee, I S Lee, J Lee, J Y Lee, M H Lee, S H Lee, S M Lee, Y J Lee, D S Leonard, N T Luan, V H A Machado, B B Manzato, R H Maruyama, R J Neal, S L Olsen, H K Park, H S Park, J C Park, J S Park, K S Park, K Park, S D Park, R L C Pitta, H Prihtiadi, S J Ra, C Rott, K A Shin, D F F S Cavalcante, M K Son, N J C Spooner, L T Truc, L Yang, G H Yu, J Amaré, J Apilluelo, S Cebrián, D Cintas, I Coarasa, E García, M Martínez, Y Ortigoza, A Ortiz De Solórzano, T Pardo, J Puimedón, M L Sarsa, C Seoane

Faculty and Staff Publications

The annual modulation signal, claimed to be consistent with dark matter as observed by DAMA/LIBRA in a sodium-iodide based detector, has persisted for over two decades. COSINE-100 and ANAIS-112 were designed to test the claim directly using the same target material. COSINE-100, located at Yangyang Underground Laboratory in South Korea, and ANAIS-112, located at Canfranc Underground Laboratory in Spain, have been taking data since 2016 and 2017, respectively. Each experiment published its respective results independently. In this Letter, we present the results of an annual modulation search as a test of the signal observed by DAMA/LIBRA with the first three …

Synoptic-Scale Meteorological Patterns Associated With Extreme Precipitation Over The Contiguous United States And Concomitant Seasonal And Regional Variability, Amy M. Johnson

Dissertations and Theses

Seasonal and spatial variations of synoptic-scale weather patterns concurrent to extreme precipitation days, defined as days above the seasonal 95th percentile of the daily precipitation distribution, are characterized over a 44-year period (1980-2023) for the Contiguous United States (CONUS). Using atmospheric reanalysis data and a grid-cell centered approach, we construct seasonal anomaly composite patterns for sea level-pressure (SLP), integrated water vapor transport, 500 hPa geopotential height (Z500), and 300 hPa wind speed. Atmospheric variables known to be important for extreme precipitation. By interpolating composites for each grid cell onto the same polar coordinate grid relative to the grid cell we …

Board Of Trustees Plumbers And Pipefitters Local V. Jones Lang Lasalle Americas Inc

2025 Decisions

USDC for the District of Delaware

Floral Trait Diversity Supports Multiple Pollination Systems Across Urban Habitats In One Of The World's Greenest Cities, Ana Paula Sales De Araujo Franco, Maxwell Da Rosa Oliveira, Evaldo Benedito De Souza, Ingrid Lohani Degering Brand, Marcus Paulo Goncalves Rosa, Bruno Henrique Dos Santos Ferreira, Maria Rosângela Sigrist

Turkish Journal of Botany

Green cities comprise a variety of habitats subject to different levels of anthropogenic pressure, ranging from completely unvegetated areas to vast green spaces such as linear parks. In this scenario, cities can support different ecological processes and ecosystem functions, which vary qualitatively and quantitatively between different habitat types along the urbanization gradient. Specifically, green spaces and ruderal plants can support pollination services in urban ecosystems, providing food resources (e.g., nectar, pollen, oil), reproduction supports (copulation sites), and nesting sites for pollinators. As a result, plant species and their floral resources are important for pollinator diversity and the maintenance of the …

Agenda (9-19-2025), California State University, San Bernardino - Associated Students, Incorporated

Associated Students, Incorporated records

No abstract provided.

Trends And Disparities In Acute Coronary Syndrome-Related Mortality In The United States: Implications For Healthcare, Muhammad Khuzzaim Khan, Ibrahim Ahmed Khan, Abdul Moiz Javed, Arslan Wazir, Hira Saleem, Muhammad Zohaib, Faisal Rasheed, Priyanka Mohan Lal, Syeda Laiba Sherazi, Amiaz Karim, Nikhil Duseja, Hussam Al Hennawi

Abington Jefferson Health Papers

Acute coronary syndrome (ACS) is a major cause of morbidity and mortality in the United States (US). However, the trends and disparities in ACS mortality are not well understood. This study aimed to analyze the ACS mortality in the US from 1999 to 2020 using the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database. The age-adjusted mortality rates (AAMR) due to ACS were calculated for each year from 1999 to 2020, stratified by sex, race, urbanization, and state. The trends and disparities in AAMR were examined using descriptive statistics and graphical methods. The AAMR due …

Medical Guidelines For Fibrodysplasia Ossificans Progressiva, Frederick S. Kaplan, Mona Al Mukaddam, Genevieve Baujat, Alberto Hidalgo Bravo, Matthew Brown, Amanda Cali, Tae-Joon Cho, Corrie Crowe, Carmen L. De Cunto, Patricia L. R. Delai, Robert J. Diecidue, Elisabeth Marelise W Eekhoff, Lisa Friedlander, Clive S. Friedman, Zvi Grunwald, Nobuhiko Haga, Edward C. Hsiao, Richard Keen, Joseph A. Kitterman, Charles Levy, Vrisha Madhuri, Rolf Morhart, J. Coen Netelenbos, Christiaan Scott, Eileen M. Shore, Michael Zasloff, Keqin Zhang, Robert J. Pignolo

Department of Oral and Maxillofacial Surgery Faculty Papers

Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare genetic condition characterized by congenital malformations of the great toes and progressive heterotopic ossification (HO) in specific anatomic patterns. Present management summarized here is focused on early diagnosis, assiduous avoidance of injury and iatrogenic harm, symptomatic amelioration of painful flare-ups, and optimization of residual function. Twenty-one members of the International Clinical Council on FOP (ICC) and seven consultants from 15 countries, chosen for their clinical expertise in FOP, developed this summary statement. Further advances in therapeutics will be based on rigorous clinical trials to assess novel and emerging treatment and prevention strategies. A …

Before “Once Upon A Time”: Creative Class Exercises That May Foster Law Student Proficiency In Gathering Information During A Client Interview, Laura A. Frase

St. Mary's Law Journal

No abstract provided.

Cover And Contents

Turkish Journal of Botany

No abstract provided.

The Militia Ii: Armed Self-Defense, The Second Amendment, And The Citizen, Marcus Armstrong

St. Mary's Law Journal

No abstract provided.

Multiple Pathways Of Social Impairment For Youth With Symptoms Of Adhd: A Novel Model Of Serial Mediation, Ewald Michael Wefelmeyer

Dissertations (1934 -)

The current study sought to explain the heterogeneity of social impairment among youth with symptoms of ADHD with the goal of potentially improving a clinician's ability to identify and support those children. A novel model of the relationship between the disorder and social impairment was proposed with serial mediators of parental/family functioning and emotion regulation. It was anticipated that a higher level of ADHD symptoms would lead to more impairment among aspects of parental/family functioning, which would predict more emotion dysregulation which would subsequently predict poorer social functioning. Structural Equation Modeling yielded little support for the overall model and no …

Music For Self-Care, A Nurse Well-Being Strategy, Kristen Gilmore Msn, Rn, Cen, Tcrn, Ne-Bc, Nc-Bc, Allison Mccrea Mmt, Mt-Bc, Stephen Didonato Phd, Lcp

Jefferson Hospital Staff Papers and Presentations

Background

• Evidence suggests that individuals with trauma exposure, such as the impact of crisis such as COVID-19, may benefit from music therapy.
• In 2021, the Hospital and Healthsystem Association of Pennsylvania (HAP) recognized the importance of ensuring well-being of the nursing workforce identifying the vital role that nursing plays upholding the highest standards of patient care.
• HAP, in partnership with the Pennsylvania Council on the Arts, created a three year, first of its kind program, to support the provision of music therapy program services for healthcare workers.
• Through this grant-funded program, Jefferson Health- Pennsylvania hospitals, were awarded $162,000. This grant …

Validation Of The Jefferson Health-Related Social Needs Screener, Sara Beachy, Kristin L. Rising, Richard W. Hass, Terry Hyslop, Isabella Muti, Mackenzie Kemp, Rhea E. Powell, Cara Martino, Baligh R. Yehia, Joseph G. Cacchione, Patricia C. Henwood

Jefferson Hospital Staff Papers and Presentations

INTRODUCTION: Screening for health-related social needs (HRSN) is a growing national health priority. While multiple HRSN screening tools currently exist, none to our knowledge have been evaluated using robust statistical analyses. The goal of this work is to provide results from a validation study of the Jefferson HRSN screener conducted across inpatient and outpatient settings.

METHODS: This retrospective cross-sectional psychometric study included HRSN assessments conducted across inpatient and outpatient settings with adult patients from March 2023 to May 2024. The study was conducted across a 17-hospital academic health system serving a diverse community in a 9-county area crossing two states …

Fostering Belonging Through Library Descriptions, Nicole Lewis, Sharolyn Swenson, Katie Yeo, Karen Glenn

Faculty Publications

In late 2023, the BYU Library adopted its Inclusive Metadata Policy as part of its commitment to fostering a campus culture of belonging. This policy reflects the Statement on Belonging, which affirms that we “value and embrace the variety of individual characteristics, life experiences and circumstances, perspectives, talents, and gifts of each member of the community and the richness and strength they bring to our community.”[1] Catalogers and archival processors at the library are engaging in practices of cultural humility to ensure that the language and frameworks we use to describe people, communities, and histories are inclusive and respectful. …

Community Survey Report: The Rebuild Survey Conducted In Response To The January 2025 Palisades Fire And Eaton Fire In Los Angeles County, Andrew J. Whelton, Cristiane Ferrarezzi, Lauryn Spearing, Anna Hoover, Mónica Palomo, Caitlin Proctor, Jianxi Su, Joseph Toland

Resilience to Emergencies and Disasters

No abstract provided.

Exploring Students' Perceptions Of Genai Tools In Higher Education: A Case Study, Dina Mansour Tbaishat, Maha Waleed Elfadel

All Works

As artificial intelligence transforms the educational landscape, generative artificial intelligence (GenAI) tools have become influential in enhancing learning experiences. Despite their growing presence in higher education, limited research explores how university students, especially learners in non-Western contexts, perceive these tools. This study investigates students' perceptions at a university in the UAE, focusing on five dimensions: perceived benefits, institutional support, technological self-efficacy, ethical considerations and user satisfaction. The findings reveal that students generally expressed strong agreement regarding the benefits of GenAI, demonstrated a clear sense of ethical awareness and felt confident in their technological abilities. While satisfaction levels were generally high, …

Two Essays On Health And Health Behavior In China, Jiamin Tan

Lingnan Theses (MPhil & PhD)

This thesis consists of two empirical studies on elderly mental health and on health behaviors. The first study investigates the long-term impact of childhood hunger on mental health in later life, using data from two nationally representative surveys in China. The study finds that childhood hunger exposure significantly increases the risks of depression and anxiety in later life. These effects are most pronounced among individuals exposed after age 5, suggesting that autobiographical memory formation plays an important role beyond socioeconomic and health pathways. The findings further indicate these impacts can be mitigated through economic interventions, such as welfare programs, and …

Chronic Poppers Maculopathy: Case Report And Literature Comparison Of Chronic And Acute Use, Francesco Cappellani, Caterina Gagliano, Jose S. Pulido

Wills Eye Hospital Papers

RATIONALE: Alkyl nitrites ("poppers") are recreational substances known for their vasodilatory and euphoric effects. Increasing evidence links them to a vision-threatening condition termed poppers maculopathy, characterized by foveal yellow spots and outer retinal changes on optical coherence tomography. While most reports describe acute exposure, little is known about long-term consequences. This case describes one of the longest documented durations of chronic poppers use, combined with a literature review to contextualize the clinical spectrum.

PATIENT CONCERNS: A 68-year-old man with human immunodeficiency virus, type 2 diabetes, hypertension, and depression presented with progressive central vision loss in both eyes persisting for at …

Housing Profiles For New York State Legislative Districts, Carlos Vargas-Ramos, Veronica Diaz-Torres

CUNY Centro, The Center for Puerto Rican Studies

The Housing Profiles for New York State Legislative Districts provide basic housing information for New York and all 63 Senate districts and all 150 Assembly districts, derived from U.S. Census Bureau data for 2023. The profiles provide housing data for the total population of the districts as well as the Hispanic population within those districts.

Ground-Based Modeling Of Deep-Space Risks To The Spleen And Intestine In Mice, Edith Nathalie Pineda Sotomayor

Theses and Dissertations

Deep-space missions, such as those planned for the cis-lunar space and Mars, pose unique challenges to astronaut health due to prolonged microgravity (MG) exposure and low-dose chronic irradiation (CIR). Understanding the impact of these stressors on secondary lymphoid tissues, such as the spleen and intestine, is crucial for ensuring crewmembers' well-being, given the impracticality of conducting this research with human samples. Using a ground-based facility, we exposed C57BL/6 female and male mice to CIR (1.74 Gy at a dose rate of 0.0029 Gy/h) and/or simulated MG (SMG) via hind limb unloading (HLU) for one month. Spleen and intestinal tissues were …

Epac1 Deletion Attenuates Müller Glial Pathological Activation And Mitigates Retinal Neurodegeneration In Ischemia-Induced Retinopathy, Shuizhen Shi, Fan Xia, Zhongqiao Lu, Erick Palacios, Fang Mei, Massoud Motamedi, Xiaodong Cheng, Hua Liu, Wenbo Zhang

The Brown Foundation: Institute of Molecular Medicine

Introduction: Ischemia-induced retinopathies, such as retinopathy of prematurity and proliferative diabetic retinopathy, are major causes of vision loss. Both pathological neovascularization and neuronal damage contribute to vision impairment in these conditions, yet current therapies primarily target neovascularization and may further compromise neuronal health.

Objectives: Cyclic AMP (cAMP) is a widely recognized second messenger regulating diverse physiological and pathological processes. Exchange protein directly activated by cAMP (Epac) is a recently identified effector of cAMP signaling. This study aimed to investigate the role of Epac1 in ischemia-induced retinopathy and elucidate its underlying mechanisms using a mouse model of oxygen-induced retinopathy (OIR).

Methods: …

Prenatal Metabolomics Analysis And Fetal Congenital Anomalies And Genetic Conditions: A Review Of Current Literature, Sarah Araji, Onur Turkoglu, Mohamad Ali Maktabi, Tracy Ashby, Ignatia B Van Den Veyver

Library Staff Publications

Fetal congenital anomalies and genetic disorders complicate 3%-5% of pregnancies and can have a significant impact on pregnancy outcomes. Precise and individualized prenatal diagnosis is crucial for effective counseling and management. The identification of new biomarkers holds promise for enhancing prenatal screening, diagnosis, and prognostic counseling in affected pregnancies. Recently, metabolomics has emerged as a potential adjunct in the interpretation of genetic variants identified through genome-wide sequencing for rare genetic conditions. To assess the potential of metabolomic profiling as a functional assay capable of providing deeper insights into the pathological processes and genetic findings associated with prenatal congenital anomalies, we …

Gait Analysis In Rett Syndrome: Integrating Linear And Nonlinear Techniques, Dacia Martinez Diaz, Brock Futrell, Bernhard Suter, Charles S Layne

Faculty, Staff and Students Publications

Rett syndrome is a rare neurodevelopmental disorder that significantly impairs bipedal postural control and walking ability. This study quantifies the gait characteristics of 22 females with Rett syndrome (divided into 3 age groups) and compares them with age-matched neurotypical females. Bilateral sagittal plane joint angles of the hip, knee, and ankle were analyzed. Measures included joint range of motion, stride time, peak angular velocity, angle-angle diagrams, phase portrait areas, and asymmetries. Results revealed reduced joint range of motion and angular velocity in individuals with Rett syndrome, as well as greater asymmetries in gait parameters reflecting disruptions in bilateral coordination. Phase …

Figure Data For "Investigation Of A Stable And Saturated Reference Electrode Using Metal Chlorides And Oxides In Eutectic Licl-Kcl Molten Salts", Carlos Meija, Devin Rappleye

ScholarsArchive Data

This data set provide machine readable .csv files for the figures in the publication entitled "Investigation of a stable and saturated reference electrode using metal chlorides and oxides in eutectic LiCl-KCl molten salts" in Nuclear Engineering and Technology (Volume 58, Issue 1, January 2026, 103875).

Ceuta, Melilla, And The Co-Construction Of Borders And Migrant Identities: Moroccan And Spanish Media Discourse, Farah Ali

Global Language Studies Faculty publications

Ceuta and Melilla are often the epicenter of political debates in Spain and Morocco, in part owing to their Spanish sovereignty being disputed by Morocco. This issue is further complicated by Morocco’s paradoxical role in migration to these cities, serving as a sojourn for migrants while simultaneously policing the borders that it protests. In this study, I use critical discourse analysis and media framing to analyze 200 Moroccan and Spanish news articles to highlight how migrant identities and borders are co-constructed. Findings show that borders are discursively constructed differently across countries and publication languages while also tied to migration, juxtaposing …

Human Cerebral Organoids Model Tumor Initiation And Infiltration In An Autologous Astrocyte-Supported Setting, Esther Schickel, Tamara Bender, Leon Kaysan, Simone Hufgard, Margot Mayer, David R Grosshans, Christiane Thielemann, Insa S Schroeder

Faculty, Staff and Student Publications

Efforts to efficiently target brain tumors are constrained by the dearth of appropriate models to study tumor behavior toward treatment approaches as well as potential side effects to the surrounding normal tissue. We established a reproducible cerebral organoid model of brain tumorigenesis in an autologous setting by overexpressing