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Bicentennial Volume (1825-2025), Olivier Moréteau Dec 2025

Bicentennial Volume (1825-2025), Olivier Moréteau

Journal of Civil Law Studies

No abstract provided.


Consideration, Detrimental Reliance, Promissory Estoppel Or The 1984 Commonlaw “Rodents” In The Louisiana Civil Code Of 1825, Alain Levasseur Dec 2025

Consideration, Detrimental Reliance, Promissory Estoppel Or The 1984 Commonlaw “Rodents” In The Louisiana Civil Code Of 1825, Alain Levasseur

Journal of Civil Law Studies

No abstract provided.


The Bicentennial Of The 1825 Civil Code Of Louisiana, Olivier Moréteau, Agustín Parise Dec 2025

The Bicentennial Of The 1825 Civil Code Of Louisiana, Olivier Moréteau, Agustín Parise

Journal of Civil Law Studies

No abstract provided.


Cover, Masthead & Contents Dec 2025

Cover, Masthead & Contents

Journal of Civil Law Studies

No abstract provided.


Evolutions In European Family Law: Towards A Common Core?, Frédérique Ferrand Dec 2025

Evolutions In European Family Law: Towards A Common Core?, Frédérique Ferrand

Journal of Civil Law Studies

This paper examines developments in European family law and considers whether a common core is gradually emerging. The first part is devoted to the European Union. Under the Treaties, substantive law on family matters, including the legal status of persons, falls within the competence of Member States. However, EU regulations govern jurisdiction and the recognition of court decisions and authentic instruments in several areas directly relevant for families and children in cross-border situations. Although these regulations do not directly deal with substantive family law, they can provide indirectly for a certain harmonization via uniform jurisdiction and recognition rules as well …


The Dynamics Of The Louisiana Civil Codes, Olivier Moréteau Dec 2025

The Dynamics Of The Louisiana Civil Codes, Olivier Moréteau

Journal of Civil Law Studies

This article presents a historical survey of the codification of Louisiana civil law from a dynamic perspective, aiming to identify why a digest was preferred over a code, only to be replaced by a code intended to be a better digest. Although attempts to codify Louisiana civil law reconnected it with French sources and methodology after the Spanish period and the United States' purchase, the local legal community resisted the force of codification. The abrogation of the ancient laws, a multilingual ius commune with which judges and lawyers were familiar, generated anxiety in a conservative and educated community. Additionally, a …


Printing The Civil Code Of 1825: A Bibliographic Essay, Warren Billings Dec 2025

Printing The Civil Code Of 1825: A Bibliographic Essay, Warren Billings

Journal of Civil Law Studies

No abstract provided.


Dirk Heirbaut, Redefining Codification: A Comparative History Of Civil, Commerical, And Procedural Codes, Agustín Parise Dec 2025

Dirk Heirbaut, Redefining Codification: A Comparative History Of Civil, Commerical, And Procedural Codes, Agustín Parise

Journal of Civil Law Studies

No abstract provided.


The Sources Of The Civil Code Of Louisiana, Henri Plauché Dart Dec 2025

The Sources Of The Civil Code Of Louisiana, Henri Plauché Dart

Journal of Civil Law Studies

No abstract provided.


Complete V. 17 Dec 2025

Complete V. 17

Journal of Civil Law Studies

No abstract provided.


A Bicentennial Approach To An Exegetical School Of Private Law In Louisiana, Agustín Parise Dec 2025

A Bicentennial Approach To An Exegetical School Of Private Law In Louisiana, Agustín Parise

Journal of Civil Law Studies

This paper is an expansion of the 44th Tucker Lecture on Civil Law. It deals with sources of law, codification, and the place of the civil code in the State of Louisiana. It explores to what extent it is possible to speak of the presence of an exegetical school of private law in Louisiana throughout the life of the Louisiana Civil Code. This paper is divided into five parts. First, it deals with foundational aspects of codification and of the Louisiana Civil Code. Second, it offers a conceptualization of exegesis. Third, it presents a periodization to help analyze the degree …


The Sources Of The Definition Of Legislation In The Louisiana Civil Code, Carlos Amunategui Dec 2025

The Sources Of The Definition Of Legislation In The Louisiana Civil Code, Carlos Amunategui

Journal of Civil Law Studies

No abstract provided.


The Myths And Legal Implications Of Cancel Culture, Yekun Zhou Dec 2025

The Myths And Legal Implications Of Cancel Culture, Yekun Zhou

Loyola of Los Angeles Entertainment Law Review

No abstract provided.


Empirical Naturalism In Law: Dewey, Rorty, And Holmes, Frederic Kellogg Dec 2025

Empirical Naturalism In Law: Dewey, Rorty, And Holmes, Frederic Kellogg

Dewey Studies

No abstract provided.


Laverne D. Best King, Mark Naison Dec 2025

Laverne D. Best King, Mark Naison

Oral Histories

Soror D. B. King served as the 14th Basileus from 2003-2006. She continued the legacy of outstanding service leading the chapter’s signature program AKATeens Rites of Passage.

During her administration, the chapter achieved the following:

  • The Chaplains committee was instituted.

  • The chapter won Chapter of the 2nd place,

  • Soror Pauline L Monsanto was awarded the Angel Award.

  • The chapter received an Educational Award for Reading One to One. 2004.

Soror Laverne remains dedication to the Chapter’s Signature Program, AKATeens Rites of Passage (ROP) program for high school girls, the program completed its 30th year helping girls develop leadership and life …


Front Matter, Dewey Studies Dec 2025

Front Matter, Dewey Studies

Dewey Studies

No abstract provided.


Investigating Droplet Segmentation With Machine Learning Tools, Brendan Rubel Dec 2025

Investigating Droplet Segmentation With Machine Learning Tools, Brendan Rubel

Mechanical Engineering and Materials Science Independent Study

In the study of Marangoni condensation through thermal images, a common task is to analyze the features of a single droplet. To do this, the droplet must first be segmented from the background. While this segmentation can be done by hand for small batch sizes, scalability quickly becomes an issue. As machine learning tools have historically been strong in image segmentation, this study analyzes the efficacy of implementing a U-Net machine learning model for this specific segmentation task. Through the process, tools were developed to help in the creation of training data, and algorithms were fine tuned to the specifics …


Discovery Of 5‑Chlorotryptophan-Containing Antibiotics Through Metabologenomics-Assisted High-Throughput Screening, Chantal D Bader, Isao Masuda, Angela Nichols, Edward Kalkreuter, Dong Yang, Thomas Christian, Yuko Nakano, Ya-Ming Hou, Ben Shen Dec 2025

Discovery Of 5‑Chlorotryptophan-Containing Antibiotics Through Metabologenomics-Assisted High-Throughput Screening, Chantal D Bader, Isao Masuda, Angela Nichols, Edward Kalkreuter, Dong Yang, Thomas Christian, Yuko Nakano, Ya-Ming Hou, Ben Shen

Department of Biochemistry and Molecular Biology Faculty Papers

Actinomycetota bacteria have specialized in the biosynthesis of antibacterial natural products (NPs), and extract and fraction libraries made from those strains remain a promising source of NP drug leads. Herein, we present a high-throughput screen (HTS), based on engineered Escherichia coli strains expressing the human (Trm5) or bacterial (TrmD) m1G37 tRNA methyltransferase, to discover NPs as novel anti-Gram-negative antibiotic leads. To harness the evolution of NPs with in vivo activity, the cell-based phenotypic HTS was applied to the Actinomycetota extract and fraction library at the Natural Products Discovery Center (NPDC), the Herbert Wertheim UF Scripps Institute for Biomedical …


Religious Employment And The Tensions Between Liberty And Equality, R. Shawn Gunnarson, James C. Phillips, Christopher A. Bates Dec 2025

Religious Employment And The Tensions Between Liberty And Equality, R. Shawn Gunnarson, James C. Phillips, Christopher A. Bates

BYU Law Review

Located in Title VII of the Civil Rights Act of 1964 is an exemption for religious employers that is often misunderstood. Often courts and commentators mischaracterize it as a narrow privilege for religious employers to hire people of the same religion. But the statute’s text says otherwise. This article resolves interpretive debates about the meaning and application of the religious employer exemption through a close textualist reading that discovers a new understanding of the structure of Title VII. Our approach applies the tools of textualism, the prevailing theory of statutory interpretation. Paying attention to the text and structure of Title …


The Mansion That Disney Built: Revitalizing Antitrust Enforcement In The Film Industry, Drew Chandler Dec 2025

The Mansion That Disney Built: Revitalizing Antitrust Enforcement In The Film Industry, Drew Chandler

BYU Law Review

The Paramount Decrees, for over sixty years, barred the major film studios from anticompetitive practices like vertical integration and block-booking. The Department of Justice’s decision to sunset the Decrees in 2020 came prematurely, with the movie industry today rocked by major mergers, the advent of streaming, the pandemic, lessened output due to industry strikes, and changing consumer tastes. True, the industry has changed since 1948, but those very changes call for regulatory intervention to avoid repeating the problems of the past.

For example, Disney’s recent merger and acquisition activity, together with the dominance of its in-house streaming service Disney+, is …


Titin-Related Familial Dilated Cardiomyopathy: Factors Associated With Disease Onset, Renee Johnson, Robert A Fletcher, Stacey Peters, Monique Ohanian, Magdalena Soka, Andrei Smolnikov, Katherine E Abihider, Michael J Ackerman, Flavie Ader, Mohammed M Akhtar, Ahmad S Amin, Euan A Ashley, John J Atherton, Rachel Austin, Annette F Baas, Richard D Bagnall, Samantha Barratt Ross, Jean-Louis Blouin, Emily E Brown, Henning Bundgaard, Douglas Cannie, Przemyslaw Chmielewski, Gemma Correnti, Maria Generosa Crespo-Leiro, Matteo Dal Ferro, Lisa M Dellefave-Castillo, Fernando Dominguez, Dennis Dooijes, Anne M Dybro, Youssef Ed Demri, Mohamed El Hachmi, Luis Escobar-Lopez, Sarah Jajesnica Foye, Maria Franaszczyk, Marta Gigli, Esther Gonzalez Lopez, Adeline Goudal, Sharon Graw, Michel Guipponi, Eric Haan, Jan Haas, Daniel J Hammersley, Frederikke G Hansen, Christopher S Hayward, Thomas Morris Hey, Stephane Heymans, Carolyn Y Ho, Arjan C Houweling, Jodie Ingles, Angela Ingrey, Andrew Jabbour, Paul A James, Joeri A Jansweijer, Jan D H Jongbloed, Anne M Keogh, Jose M Larrañaga-Moreira, Ronald H Lekanne Deprez, Ivan Macciocca, Peter S Macdonald, Nicolas Mansencal, Julia Mansour, Cristina Martinez-Veira, Barbara Mcdonough, Julie Mcgaughran, Kristen Medo, Marco Merlo, Ewa Michalak, Lorenzo Monserrat, Helen Mountain, Steven A Muller, Anne M Murphy, Brittney Murray, Emily C Oates, Elizabeth Ormondroyd, Nicholas Pachter, Alessia Paldino, Aurélien Palmyre, Naveen L Pereira, Kermshlise C Picard, Nicola Poplawski, Sanjay Prasad, Julie Proukhnitzky, Jean-Francois Pruny, Patricia Reant, Pascale Richard, Anne Ronan, Farbod Sedaghat-Hamedani, Christopher Semsarian, Garrett Storm, Sophie Stroeks, Petros Syrris, Matthew R G Taylor, Kate Thomson, Tina Thompson, J Peter Van Tintelen, Christoffer Rasmus Vissing, Kathryn E Waddell-Smith, Mathew Wallis, Dominica Zentner, Clare Arnott, Ali J Marian, Jaewon Oh, Siv Fokstuen, Cynthia A James, Roberto Barriales-Villa, Benjamin Meder, Karim Wahbi, John R Giudicessi, Victoria N Parikh, James S Ware, Nicolas Piriou, Caroline Rooryck, Neal K Lakdawala, Luisa Mestroni, Gianfranco Sinagra, Perry M Elliott, Hugh Watkins, Elizabeth M Mcnally, Philippe Charron, Karin Y Van Spaendonck-Zwarts, Pablo Garcia-Pavia, Maria Luisa Peña-Peña, Jens Mogensen, Alex Hoerby Christensen, Zofia T Bilińska, Torsten B Rasmussen, Jonathan G Seidman, Christine E Seidman, Anneline S J M Te Riele, Job A J Verdonschot, Yigal M Pinto, Imke Christiaans, Diane Fatkin Dec 2025

Titin-Related Familial Dilated Cardiomyopathy: Factors Associated With Disease Onset, Renee Johnson, Robert A Fletcher, Stacey Peters, Monique Ohanian, Magdalena Soka, Andrei Smolnikov, Katherine E Abihider, Michael J Ackerman, Flavie Ader, Mohammed M Akhtar, Ahmad S Amin, Euan A Ashley, John J Atherton, Rachel Austin, Annette F Baas, Richard D Bagnall, Samantha Barratt Ross, Jean-Louis Blouin, Emily E Brown, Henning Bundgaard, Douglas Cannie, Przemyslaw Chmielewski, Gemma Correnti, Maria Generosa Crespo-Leiro, Matteo Dal Ferro, Lisa M Dellefave-Castillo, Fernando Dominguez, Dennis Dooijes, Anne M Dybro, Youssef Ed Demri, Mohamed El Hachmi, Luis Escobar-Lopez, Sarah Jajesnica Foye, Maria Franaszczyk, Marta Gigli, Esther Gonzalez Lopez, Adeline Goudal, Sharon Graw, Michel Guipponi, Eric Haan, Jan Haas, Daniel J Hammersley, Frederikke G Hansen, Christopher S Hayward, Thomas Morris Hey, Stephane Heymans, Carolyn Y Ho, Arjan C Houweling, Jodie Ingles, Angela Ingrey, Andrew Jabbour, Paul A James, Joeri A Jansweijer, Jan D H Jongbloed, Anne M Keogh, Jose M Larrañaga-Moreira, Ronald H Lekanne Deprez, Ivan Macciocca, Peter S Macdonald, Nicolas Mansencal, Julia Mansour, Cristina Martinez-Veira, Barbara Mcdonough, Julie Mcgaughran, Kristen Medo, Marco Merlo, Ewa Michalak, Lorenzo Monserrat, Helen Mountain, Steven A Muller, Anne M Murphy, Brittney Murray, Emily C Oates, Elizabeth Ormondroyd, Nicholas Pachter, Alessia Paldino, Aurélien Palmyre, Naveen L Pereira, Kermshlise C Picard, Nicola Poplawski, Sanjay Prasad, Julie Proukhnitzky, Jean-Francois Pruny, Patricia Reant, Pascale Richard, Anne Ronan, Farbod Sedaghat-Hamedani, Christopher Semsarian, Garrett Storm, Sophie Stroeks, Petros Syrris, Matthew R G Taylor, Kate Thomson, Tina Thompson, J Peter Van Tintelen, Christoffer Rasmus Vissing, Kathryn E Waddell-Smith, Mathew Wallis, Dominica Zentner, Clare Arnott, Ali J Marian, Jaewon Oh, Siv Fokstuen, Cynthia A James, Roberto Barriales-Villa, Benjamin Meder, Karim Wahbi, John R Giudicessi, Victoria N Parikh, James S Ware, Nicolas Piriou, Caroline Rooryck, Neal K Lakdawala, Luisa Mestroni, Gianfranco Sinagra, Perry M Elliott, Hugh Watkins, Elizabeth M Mcnally, Philippe Charron, Karin Y Van Spaendonck-Zwarts, Pablo Garcia-Pavia, Maria Luisa Peña-Peña, Jens Mogensen, Alex Hoerby Christensen, Zofia T Bilińska, Torsten B Rasmussen, Jonathan G Seidman, Christine E Seidman, Anneline S J M Te Riele, Job A J Verdonschot, Yigal M Pinto, Imke Christiaans, Diane Fatkin

The Brown Foundation: Institute of Molecular Medicine

Background and aims: Truncating variants in the TTN gene (TTNtv) are the most common genetic cause of dilated cardiomyopathy (DCM) but also occur as incidental findings in the general population. This study investigated factors associated with the clinical manifestation of TTNtv.

Methods: An international multicentre retrospective observational study was performed in families with TTNtv-related DCM. Shared frailty models were used to estimate associations of variant characteristics with lifetime risk of DCM, and logistic regression to estimate odds ratios (ORs) for individual-level clinical risk factor profiles (cardiac conditions, cardiovascular comorbidities, lifestyle) and DCM.

Results: A total of 3158 subjects in 1043 …


Will Technology Help Us Understand Animals?, Frances I. Sacks Dec 2025

Will Technology Help Us Understand Animals?, Frances I. Sacks

Capstones

New technologies allow scientists to study animal communication like never before. Advanced surveillance devices ornament forests and oceans, recording animals over great stretches of distance and time. Artificial intelligence can absorb these enormous datasets, sorting tangled abstractions into coherent patterns. With a sufficiently robust library of analyzed data, some researchers believe that large language models will soon learn to translate whale communication systems.

https://docs.google.com/document/d/1ky6mPFjc-lNJFVK8CHebUa5zCSFUoMgkCB560pqxwfo/edit?tab=t.0


Bread And Circuses, Rosie Thomas Dec 2025

Bread And Circuses, Rosie Thomas

Capstones

This project documents clowns and their props and performance and rehearsal spaces in New York in the fall of 2025. The photos explore the surreality of practicing performance and indulging in art. I am asking what it means to have and explore creativity - queerness, weirdness, community, and play - while acknowledging that a community that gathers to exhibit their own freedom of expression is making an active choice and a prioritisation at every moment.


Bilingual English-Spanish Louisiana Civil Code, Book Iii, Title Vi, Mariano Vitetta Dec 2025

Bilingual English-Spanish Louisiana Civil Code, Book Iii, Title Vi, Mariano Vitetta

Journal of Civil Law Studies

No abstract provided.


Investigating Chronic Toxicity, Diet, Patient-Reported Outcomes And The Microbiome In Immunotherapy-Treated Metastatic Melanoma Survivors: A New Frontier, Margaux Robert, Satabdi Saha, Nazli Dizman, Michelle Rohlfs, Elizabeth Sirmans, Julie Simon, Rodabe N Amaria, Isabella C Glitza Oliva, Hussein A Tawbi, Michael A Davies, Alexandra Ikeguchi, Karen Basen-Engquist, Keri Schadler, Michael E Roth, Wenye Song, Xiaotao Zhang, Nadim J Ajami, Lorenzo Cohen, Jennifer A Wargo, Christine B Peterson, Jennifer L Mcquade, Carrie R Daniel Dec 2025

Investigating Chronic Toxicity, Diet, Patient-Reported Outcomes And The Microbiome In Immunotherapy-Treated Metastatic Melanoma Survivors: A New Frontier, Margaux Robert, Satabdi Saha, Nazli Dizman, Michelle Rohlfs, Elizabeth Sirmans, Julie Simon, Rodabe N Amaria, Isabella C Glitza Oliva, Hussein A Tawbi, Michael A Davies, Alexandra Ikeguchi, Karen Basen-Engquist, Keri Schadler, Michael E Roth, Wenye Song, Xiaotao Zhang, Nadim J Ajami, Lorenzo Cohen, Jennifer A Wargo, Christine B Peterson, Jennifer L Mcquade, Carrie R Daniel

Faculty, Staff and Student Publications

Background/Objectives: Immune checkpoint blockade (ICB) therapies have significantly improved outcomes in metastatic melanoma. However, immune-related adverse events (irAEs) and persistent chronic toxicities (CTs) among this emerging survivor population likely influence different facets of quality of life. This study characterized CT, patient-reported outcomes (PROs), diet, physical activity and gut microbiome features in a cohort of long-term survivors with a history of ICB-treated metastatic melanoma.

Methods: Forty-eight patients with a history of metastatic melanoma who initiated ICB treatment at least 3 years earlier and were not currently on treatment were prospectively enrolled from a melanoma survivorship clinic. Participants completed screening …


Epcam Activates The Erk-Egr1 Signaling Axis And Promotes Tnf-Α-Induced The Progression Of Anaplastic Thyroid Cancer, Chi-Chiu Lee, Yi-Jen Su, Sushree Shankar Panda, Chiung-Yi Chiu, Chung-Hsuan Wu, Tsai-Ming Lu, Pi-Chun Li, Yen-Lin Huang, Ruey-Long Hong, Shao-Hsi Hung, Cassian Yee, Stephen Y Lai, Han-Chung Wu Dec 2025

Epcam Activates The Erk-Egr1 Signaling Axis And Promotes Tnf-Α-Induced The Progression Of Anaplastic Thyroid Cancer, Chi-Chiu Lee, Yi-Jen Su, Sushree Shankar Panda, Chiung-Yi Chiu, Chung-Hsuan Wu, Tsai-Ming Lu, Pi-Chun Li, Yen-Lin Huang, Ruey-Long Hong, Shao-Hsi Hung, Cassian Yee, Stephen Y Lai, Han-Chung Wu

Faculty, Staff and Student Publications

Background: Epithelial cell adhesion molecule (EpCAM) is a pleotropic transmembrane glycoprotein comprising an extracellular domain (EpEX), a single transmembrane domain, and an intracellular domain (EpICD). For several types of cancer, high EpCAM expression is associated with tumor progression, metastasis, immune evasion, and overall poor prognosis. A rare but aggressive form of thyroid cancer, anaplastic thyroid cancer (ATC), has a mean survival time of only 3–6 months after diagnosis.

Methods: The levels of EpEX and EpICD cleavage in clinical patient samples was evaluated by using tissue microarray. Capture enzyme-linked immunosorbent assay (ELISA) was conducted to explore the of shedding EpEX and …


Video Conversation Aids To Assist In Goals-Of-Care Discussions With Older Adults In A Medical Setting: A Systematic Review, Ashna S Karpe, Mokunfayo O Fajemisin, Stephanie Martinez Ugarte, Lara Ouellette, Martin L Blakely, Gina H Khraish, Shreyans V Sanghvi, Min J Kwak, Jessica L Lee, Lillian S Kao, Thaddeus J Puzio Dec 2025

Video Conversation Aids To Assist In Goals-Of-Care Discussions With Older Adults In A Medical Setting: A Systematic Review, Ashna S Karpe, Mokunfayo O Fajemisin, Stephanie Martinez Ugarte, Lara Ouellette, Martin L Blakely, Gina H Khraish, Shreyans V Sanghvi, Min J Kwak, Jessica L Lee, Lillian S Kao, Thaddeus J Puzio

Library Staff Publications

Background

Goals-of-care (GOC) discussions align medical treatment with older adults’ preferences, yet are hindered by communication barriers, provider discomfort, and misinformation. Video-based decision aids improve understanding and reduce decision conflict, though data on their use in older populations remain limited. This review aimed to determine the effectiveness of video-based decision aids in improving GOC discussions and decision-making outcomes among older adults.

Methods

For this systematic review, a medical librarian conducted a literature search of Medline, Embase, Web of Science, CINAHL, PsychINFO, and Cochrane from database inception through April 2025. Eligible studies evaluated a video-based aid in US adults aged ≥65 …


Discovery Of Small Molecules And A Druggable Groove That Regulate Dna Binding And Release Of The Ap-1 Transcription Factor Δfosb, Sean Mcneme, Yun Young Yim, Ashwani Kumar, Yi Li, Brandon Hughes, Corey Peyton St Romain, Galina Aglyamova, Jianping Chen, Nghi D Nguyen, Shanghua Fan, Gabriel S Stephens, Wen-Ning Zhao, Samantha Kruzshak, Molly Estill, Corrine Brener, Solange Tofani, Anil Kumar, Earnest P Chen, Nadeen Takatka, Alfred J Robison, Haiying Chen, Reid T Powell, Stephen J Haggarty, Clifford Stephan, Eric J Nestler, Jeannie Chin, Mischa Machius, Jia Zhou, Gabby Rudenko Dec 2025

Discovery Of Small Molecules And A Druggable Groove That Regulate Dna Binding And Release Of The Ap-1 Transcription Factor Δfosb, Sean Mcneme, Yun Young Yim, Ashwani Kumar, Yi Li, Brandon Hughes, Corey Peyton St Romain, Galina Aglyamova, Jianping Chen, Nghi D Nguyen, Shanghua Fan, Gabriel S Stephens, Wen-Ning Zhao, Samantha Kruzshak, Molly Estill, Corrine Brener, Solange Tofani, Anil Kumar, Earnest P Chen, Nadeen Takatka, Alfred J Robison, Haiying Chen, Reid T Powell, Stephen J Haggarty, Clifford Stephan, Eric J Nestler, Jeannie Chin, Mischa Machius, Jia Zhou, Gabby Rudenko

Faculty, Staff and Students Publications

ΔFOSB, a member of the AP-1 family of transcription factors, mediates long-term neuroadaptations underlying drug addiction, seizure-related cognitive decline, dyskinesias, and several other chronic conditions. AP-1 transcription factors are notoriously difficult to modulate pharmacologically due to the absence of well-defined binding pockets. Here, we identify a novel site on ΔFOSB, located outside the DNA-binding cleft, that accommodates small molecules. We show that sulfonic acid-containing compounds bind to this site via an induced-fit mechanism, reorienting side chains critical for DNA binding, and that they may hinder the ΔFOSB bZIP α-helix from binding to the major groove of DNA. In vivo, direct …


Charters In Patient-Engaged Research: A Scoping Review Of Current Evidence, Jenny Martínez, Catherine V. Piersol, Richard W. Hass, Felicia Chew, Amy Cunningham, Sharon L. Larson Dec 2025

Charters In Patient-Engaged Research: A Scoping Review Of Current Evidence, Jenny Martínez, Catherine V. Piersol, Richard W. Hass, Felicia Chew, Amy Cunningham, Sharon L. Larson

College of Population Health Faculty Papers

AIMS: Research study charters facilitate shared governance and power sharing with research partners when developed collaboratively and early on in a study. Study charters are negotiated and developed on a study-by-study basis, offering insight into study-specific dynamics between research partners and investigators, as well as the factors that each identify as important for their collaboration. This review aimed to map and synthesize existing evidence on the development, structure, and implementation of research study charters used in patient-engaged research.

METHODS: We searched peer-reviewed literature published worldwide in English between January 2019 and January 2025.

RESULTS: Our final sample consisted of 17 …


The Bridwell Quill: Issues 86–88: If On A Single Night A Traveler, Anthony J. Elia Dec 2025

The Bridwell Quill: Issues 86–88: If On A Single Night A Traveler, Anthony J. Elia

Bridwell Library Publications

No abstract provided.