Digital Commons Network^™

Circumbinary Disk Evolution In The Presence Of An Outer Companion Star, Rebecca G. Marin, Stephen Lepp, Stephen H. Lubow, Matthew A. Kenworthy, Grant M. Kennedy, David Vallet

Physics & Astronomy Faculty Research

We consider a hierarchical triple system consisting of an inner eccentric binary with an outer companion. A highly misaligned circumbinary disk around the inner binary is subject to two competing effects: (i) nodal precession about the inner binary eccentricity vector that leads to an increase in misalignment (polar alignment) and (ii) Kozai–Lidov (KL) oscillations of eccentricity and inclination driven by the outer companion that leads to a reduction in the misalignment. The outcome depends upon the ratio of the timescales of these effects. If the inner binary torque dominates, then the disk aligns to a polar orientation. If the outer …

Rare Occurrence Of Pseudomyxoma Peritonei (Pmp) Syndrome Arising From A Malignant Transformed Ovarian Primary Mature Cystic Teratoma Treated By Cytoreductive Surgery And Hipec: A Case Report, Francesca Ponzini, Luke Kowal, Mariam Ghafoor, Allison F Goldberg, Joanna Chan, Ryan Lamm, Shawnna Cannaday, Scott D. Richard, Avinoam Nevler, Harish Lavu, Wilbur Bowne, Norman G Rosenblum

Department of Surgery Faculty Papers

Background: Pseudomyxoma peritonei (PMP) syndrome is a disease process that typically occurs from ruptured appendiceal mucocele neoplasms. PMP syndrome arising from malignant transformation of an ovarian primary mature cystic teratoma (MCT) is a pathogenesis rarely encountered.

Case presentation: Herein, we report a 28-year-old patient evaluated and treated for a right ovarian mass and large volume symptomatic abdominopelvic mucinous ascites. Molecular profiling and genetic analysis revealed mutations in ATM, GNAS, and KRAS proteins while IHC demonstrated gastrointestinal-specific staining for CK20, CDX2, CK7, and SATB2. Peritoneal cytology showed paucicellular mucin. Diffuse peritoneal adenomucinosis (DPAM) variant of PMP arising from a ruptured ovarian …

Deepreal: A Deep Learning Powered Multi-Scalemodeling Framework For Predicting Out-Of-Distributionligand-Induced Gpcr Activity, Tian Cai, Kyra Alyssa Abbu, Yang Liu, Lei Xie

Publications and Research

Motivation Drug discovery has witnessed intensive exploration of predictive modeling of drug–target physical interactions over two decades. However, a critical knowledge gap needs to be filled for correlating drug–target interactions with clinical outcomes: predicting genome-wide receptor activities or function selectivity, especially agonist versus antagonist, induced by novel chemicals. Two major obstacles compound the difficulty on this task: known data of receptor activity is far too scarce to train a robust model in light of genome-scale applications, and real-world applications need to deploy a model on data from various shifted distributions.

Results To address these challenges, we have developed an end-to-end …

The Ability To Classify Patients Based On Gene-Expression Data Varies By Algorithm And Performance Metric, Stephen Piccolo, Avery Mecham, Nathan P. Golightly, Jérémie L. Johnson, Dustin B. Miller

Faculty Publications

By classifying patients into subgroups, clinicians can provide more effective care than using a uniform approach for all patients. Such subgroups might include patients with a particular disease subtype, patients with a good (or poor) prognosis, or patients most (or least) likely to respond to a particular therapy. Transcriptomic measurements reflect the downstream effects of genomic and epigenomic variations. However, high-throughput technologies generate thousands of measurements per patient, and complex dependencies exist among genes, so it may be infeasible to classify patients using traditional statistical models. Machine-learning classification algorithms can help with this problem. However, hundreds of classification algorithms exist—and …

Fully Differential Investigation Of Two-Center Interference In Dissociative Capture In P + H₂ Collisions, S. Bastola, M. Dhital, B. Lamichhane, A. Silvus, R. Lomsadze, J. Davis, A. Hasan, A. Igarashi, Michael Schulz

Physics Faculty Research & Creative Works

We have measured and calculated fully differential cross sections for vibrational dissociation following capture in 75-keV p + H₂ collisions. For a molecular orientation perpendicular to the projectile beam axis and parallel to the transverse momentum transfer we observe a pronounced interference structure. The positions of the interference extrema suggest that the interference term is afflicted with a phase shift which depends on the projectile scattering angle. However, no significant dependence on the kinetic-energy release was observed. Considerable discrepancies between our calculations and experimental data were found.

Seismic Performance Design Criteria Of Existing Bridge Bent Plastic Hinge Region And Rapid Repair Measures Of Earthquake Damaged Bridges Considering Future Resilience, A K M Golam Murtuz

Dissertations and Theses

The main objective of this research was to evaluate the seismic performance of existing sub-standard reinforced concrete (RC) bridge column-spread footing subassemblies and to quantify the material strain limits through a full-scale experimental program. A total of six column-footing test specimens with pre-1990 construction details were subjected to reverse cyclic lateral loading, utilizing a conventional three-cycle symmetric loading protocol and a protocol representing the demands expected from a CSZ earthquake. Additionally, the tests were designed so that variable axial loading could be applied to simulate the secondary load effects experienced during an earthquake in a column that is part of …

Quantification Of Reynolds Shear Stress Wave-Phase Dependence In Fixed-Bottom Offshore Wind Turbine Via Quadrant Analysis, Cerrina Mouchref

University Honors Theses

As the need for a reliable renewable energy supply is increasing, many have looked to offshore wind because they hold more potential for power production than onshore wind. Interests in expanding offshore wind energy has brought along many challenges when it comes to understanding the complex dynamics experienced offshore, including the relationship between the wind-turbine generated wakes and ocean waves. This experimental study characterizes the relationship between Reynolds shear stress and the phase of surface waves above the air-sea interface in the wind-turbine wake region. The experimental setup combines a wave tank, wind tunnel, and a fixed-bottom wind turbine. Particle …

Triglyceride-Rich Lipoproteins, Apolipoprotein C-Iii, Angiopoietin-Like Protein 3, And Cardiovascular Events In Older Adults: Atherosclerosis Risk In Communities (Aric) Study, Aliza Hussain, Caroline Sun, Elizabeth Selvin, Vijay Nambi, Josef Coresh, Xiaoming Jia, Christie M Ballantyne, Ron C Hoogeveen

Faculty, Staff and Students Publications

AIMS: Despite statin and antihypertensive therapies, older Americans have high atherosclerotic cardiovascular disease (ASCVD) risk. Novel measures of triglyceride-rich lipoproteins, low-density lipoprotein triglycerides (LDL-TG), and remnant-like particle cholesterol (RLP-C), are associated with ASCVD in middle-aged adults. Polymorphisms in genes encoding angiopoietin-related protein 3 (ANGPTL3) and apolipoprotein C-III (apoC-III), two proteins involved in triglyceride catabolism, are associated with increased risk for hypertriglyceridaemia and ASCVD and are potential therapeutic targets. We examined associations of LDL-TG, RLP-C, apoC-III, and ANGPTL3 levels with ASCVD events in older adults in the Atherosclerosis Risk in Communities (ARIC) study.

METHODS AND RESULTS: In 6359 participants (mean age …

Triglyceride-Rich Lipoproteins, Apolipoprotein C-Iii, Angiopoietin-Like Protein 3, And Cardiovascular Events In Older Adults: Atherosclerosis Risk In Communities (Aric) Study, Aliza Hussain, Caroline Sun, Elizabeth Selvin, Vijay Nambi, Josef Coresh, Xiaoming Jia, Christie M Ballantyne, Ron C Hoogeveen

Faculty, Staff and Students Publications

AIMS: Despite statin and antihypertensive therapies, older Americans have high atherosclerotic cardiovascular disease (ASCVD) risk. Novel measures of triglyceride-rich lipoproteins, low-density lipoprotein triglycerides (LDL-TG), and remnant-like particle cholesterol (RLP-C), are associated with ASCVD in middle-aged adults. Polymorphisms in genes encoding angiopoietin-related protein 3 (ANGPTL3) and apolipoprotein C-III (apoC-III), two proteins involved in triglyceride catabolism, are associated with increased risk for hypertriglyceridaemia and ASCVD and are potential therapeutic targets. We examined associations of LDL-TG, RLP-C, apoC-III, and ANGPTL3 levels with ASCVD events in older adults in the Atherosclerosis Risk in Communities (ARIC) study.

METHODS AND RESULTS: In 6359 participants (mean age …

County Of Maui V. Hawaii Wildlife Fund And Its Impact On Clean Water Act Jurisprudence, Sydney Bale

Oil and Gas, Natural Resources, and Energy Journal

No abstract provided.

Review Of Lead, Kindly Light: Gandhi On Christianity, Charles R. Disalvo

The Journal of Social Encounters

No abstract provided.

Review Essay: A Contribution To The Debates About Law, Non-Violence, And The Struggle For Democracy, Walter J. Kendall Lll

The Journal of Social Encounters

No abstract provided.

Classics Revisited Review Essay: Pedagogy Of The Oppressed, 50th Anniversary Edition, Kathleen Maas Weigert

The Journal of Social Encounters

No abstract provided.

The 1676 Project: Black And White Together In The U.S.A., Danny Duncan Collum

The Journal of Social Encounters

America’s post-George Floyd racial reckoning has brought a new focus on the country’s history of enslavement, segregation and systemic racism. However, this reckoning has often failed to recognize that the roots of systemic racism lie in the need of the wealthy planters in colonial Virginia to divide the African and English indentured servants who constituted a majority threatening to elite power. Nor do contemporary versions of U.S. history always account for the persistent reoccurrence of class-based interracial movements, such as the late 19^th century Populists, or their promise as a long-term solution to the country’s racial divides.

Developing Communicative Competence Of Esp Learners, Feruza Dauletbaevna Atashova, Guljakhan Mirzagalievna Seytniyazova

Mental Enlightenment Scientific-Methodological Journal

Maqolada kommunikativ faoliyat turlari, ularni tartibga solish va kommunikativ o'qitish usullari haqida gap boradi. Turli xil o'quv maqsadlariga erishadigan to'rt xil kommunikativ faoliyat turlarining tavsifi mavjud. Ular har xil turdagi vazifalarga eng mos keladi, har xil turdagi o'tirish tartibini talab qiladi va turli xil ijtimoiy munosabatlarni jalb qiladi yoki rag'batlantiradi. Faoliyat davomida guruh a'zolarining eng yaxshi o'tiradigan joylashuvi tartibning muhim xususiyatlarini qo'llab-quvvatlaydi. Har bir o'quvchi o'z ma'lumotlarining o'ziga xosligini saqlab qolgan holda muhim ma'lumotlarni olish uchun boshqalardan teng foydalanish imkoniyatiga ega bo'lishi kerak. Biz tadqiqot natijalarini umumlashtiramiz va ishning nazariy va amaliy ahamiyatini isbotlaymiz va xulosa qilamiz.

The Concept Of Competence Approach In Teaching A Foreign Language, Feruza Dauletbaevna Atashova, Gabidden Urazbaevich Konisov

Mental Enlightenment Scientific-Methodological Journal

This article is devoted to the theoretical background of the communicative competence and the description of the development of foreign communicative competence as a goal of teaching a foreign language. Here we describe the development of the main linguistic and methodological principles, as well as the parameters of the description of foreign languages for the purpose of teaching them; the implementation of this theoretical basis of the reform in the teaching of foreign languages was carried out within the framework of a number of interrelated projects. The key to successful speech activity of students are also non-traditional forms of English …

Comparative Analysis Of Phonological Formation Of Reduplication In English And Uzbek Languages, Dilobar Bakhtiyor Kizi Begimkulova

Mental Enlightenment Scientific-Methodological Journal

This article examines reduplication in English and Uzbek as a phonological phenomenon, its degree of investigation in English linguistics, the interpretation of the concept of reduplication in English and Uzbek, their similarities and differences. At the same time, the status of reduplication in the language system, the phonological aspects, classification and linguistic features of their language expression are analyzed comparatively. The ideas have been proven by discussing a number of specific examples and their meanings. The analysis of reduplicative units was carried out on the basis of explanatory and bilingual dictionaries in English and Uzbek languages, examples from the fiction, …

The Notion Of Synchronic Translation, Its History Of Development And The Extension Of Its Usage, Azamat Eshonkulov

Mental Enlightenment Scientific-Methodological Journal

General concepts related to synchronic translation illustrate that it is very broad area of oral translation. In the following article, we are going to discuss general information dealing with this branch of translation, in which we look into the emergence of simultaneous interpretation as well as considering the differences between the types of oral translation. And we try to highlight theoretical basis of simultaneous interpretation which were presented by the scientists who even currently work as professional interpreters. Now that the huge demand for simultaneous interpretation is increasing, it is incredibly essential to gain fundamental background on the synchronic translational …

Uzbek Translations Of Some English Proverbs And Translation Problems, Shuhratjon Mashrapovich Boykhanov

Mental Enlightenment Scientific-Methodological Journal

Idiomatic expressions, proverbs and sayings are closely connected with a particular nation’s culture and history. For this reason, they are hardly understood by other nations. This is one of the reasons causes some scholars have a point that those kinds of lexical items cannot be translated; however, other authors proposed different translation techniques to find solutions to this problem. This article analyzes particularly this problem. In conducting this research, comparative, contrastive, and content analyses were utilized. To test different scholars’ opposite views, nine English proverbs were randomly selected and translated into Uzbek. Descriptive analysis revealed that one out of nine …

Teachining Communication Technologies In Modern Foreign Languages, Gulnoz Uzokovna Komilova, Maxbuba Bozorovna Ostonova

Mental Enlightenment Scientific-Methodological Journal

In this article will discuss the most important tasks today is the use of rapidly developing information and communication technologies (ICT), a new approach to the educational process and its creation. A great example of this is the increased emphasis on ICT in teaching foreign languages. Constantly increasing demands to the level of training of modern professionals make the teachers of higher educational institutions increasingly turn to the problem of increasing the effectiveness of training through innovative methods developed at universities.

Methods Of Developing Intercultural Competence Of Future Teachers In The Condition Of Teaching A Foreign Language, Feruza Komiljanovna Kurbanova

Mental Enlightenment Scientific-Methodological Journal

Ushbu maqolada biz talabalarning chet tilini o'rganishdagi madaniyatlararo kompetensiyasi, mavzuga oid ba'zi masalalar va dars davomida muvaffaqiyatga erishish yo'llari haqida gapirishni maqsad qilganmiz. “Asl dunyo” va “maqsadli jamiyat olami” o‘rtasidagi munosabatni bilish, anglash va tushunish (o‘xshashlik va farqlovchi farqlar) madaniyatlararo ongni hosil qiladi. Albatta, shuni ta'kidlash kerakki, madaniyatlararo xabardorlik ikki dunyoda mintaqaviy va ijtimoiy xilma-xillikdan xabardorlikni o'z ichiga oladi. Ob'ektiv bilimga qo'shimcha ravishda, madaniyatlararo xabardorlik har bir jamoa boshqasining nuqtai nazaridan, ko'pincha milliy stereotiplar ko'rinishida paydo bo'lishi haqida xabardorlikni qamrab oladi. Ko'p tilli va ko'p madaniyatli kompetentsiya odatda bir yoki bir nechta usulda notekisdir. Bunday nomutanosibliklar mutlaqo normaldir. “Ona tili”da …

Slang - As A Specific Phenomenon To Colloquial Speech, Abduvali Musaev

Mental Enlightenment Scientific-Methodological Journal

In this article, it is important to study the words that correspond to the jargon as a phenomenon specific to slang-speech, to identify words belonging to dialects, dialects, professions in order to determine what opportunities exist in Uzbek colloquial speech.

Similarities In Poetic Ideas In A. Fitrat’S “Satan’S Rebellion Against God” And G.G. Byron's “Cain”, Parda Akhmedovich Kurbonov

Mental Enlightenment Scientific-Methodological Journal

O'zbek adibi, dramaturg, shoir Abdurauf Fitratning “Shaytonning tangriga isyonlari” asarlarida xalqni qullik asoratiga solgan jabr-zulm, istibdod tuzumiga qarshi g'oyalarni oldinga surdi. Ingliz shoiri JGBayronning “Kain” dramasida ham bir kichik poetik goya bor. Lyutsifer (Shayton) aralashmaganida ham Odam farzand ruhida mana shu ishonkorlik, hurfikrlikka intilish bor edi. Shayton uni faqat tezlashtirdi. Bayronsidagi Kain va Lyutsifer she'rlari bilan Fitrat dramasidagi Shayton so'zlari ostidagi g'oyaviy dramatik bor. Xil ikkala asarda insonlarning faqat qullab yashashi, muteylik, laganbarlik, yaratganga madhu sano aytilishi ko'rinadi. Xil ikki asarda fikrsizlik, fikrlamay, faqat Yaratganga hamdu sano aytish, qabul qilish, erkin fikrlamas tubanlik, pastkashlik kabi sifatlarning qo'

The Differences Between Genders In Learning Languages, Dilafruz Nematjanova

Mental Enlightenment Scientific-Methodological Journal

This article mainly discusses the differences between the sexes in language acquisition in recent years and the biological, neurological, and environmental considerations that lead women and men to learn other languages in different ways.

The Concept Of Alliteration And Its Functions, Zebo Nizomova

Mental Enlightenment Scientific-Methodological Journal

Alliteration has become an important part of poetry of all time. Alliteration is a means of sound writing; repetition of the supporting consonant, which is, immediately preceding the stressed vowel, as well as the repetition of the initial consonant in different words of the same speech segment; a stylistic device aimed at enhancing the expressiveness of artistic speech, especially verse. In this article, we will analyze the definitions of alliteration in order to create more favorable conditions for comparing foreign texts using this technique and their translation versions in Uzbek. Along with the definitions, we will discuss the functions of …

Sports Terminology As A Source Of Synonymy In Language: The Case Of Uzbek Language, Qodir Turdiyevich Ruziyev

Mental Enlightenment Scientific-Methodological Journal

Modern sports and their terminologies in European and other languages have been strongly influenced by English. In spite of our country being under the influence of the former Soviet Union for a long period, we can still see a lot of foreign sports terminology together with Russian terminologies in Uzbek language. Most sports terminologies are Russian because they come through Russian. The reason is that some of the most popular sports originating in European countries have been exported to other countries together with established terminology. There are several possibilities of how to transfer terminology into recipient languages: to borrow and …

Translation Of Russian Languages To Uzbek Language, Dilfuza Daminovna Turaeva

Mental Enlightenment Scientific-Methodological Journal

In the works translated from Russian into Uzbek, on the other hand, translators often resort to visual aids. Because these field tools perform a variety of methodological and pragmatic tasks in a literary text, the translator uses them effectively. In the first case, the translator can perceive a semantic image of a verb or adjective in Russian and translate it in the translation by means of a word belonging to an independent category derived from a figurative word. This not only increases the informativeness, emotionality, or expressiveness of the text, but also does not violate the requirement of a volume …

Applying Innovative Teaching Methods In A Second Language Classroom, Akmal Amirovich Xamzaev, Almat Raxmonovich Abdullayev

Mental Enlightenment Scientific-Methodological Journal

This article deals with the level of using creative teaching methodologies in second language classroom as studied by the researcher. A series of qualitative methods such as using newspaper, media, movies, interpreting advertisements can be employed in the classroom in order to develop students’ second language learning ability. The article focuses on how teaching methodologies should be modified and used in the classroom appropriately by understanding the learning capacity of students , their learning interest in the classroom and the use of creative teaching methodologies in the second language classroom .

The Importance Of Developing Speaking Skills In Foreign Language Teaching And Its Problems, Muhayyo Alisherovna Khalikova

Mental Enlightenment Scientific-Methodological Journal

The content of the article - a new method of teaching foreign languages in our country in accordance with the recommendations of the European system of assessment of knowledge and skills of foreign language teachers, the use of advanced pedagogical technologies, interactive, innovative methods, communication tools in foreign language teaching requirements are to underestimate the importance of development. It is important to create textbooks for students of secondary schools and vocational colleges. One of the most controversial aspects of the problem of foreign language teaching is the methodology of testing and accounting for knowledge, skills and competencies, and their organization …

Religious And Scientific Approaches To The Concept Of Kindness And Generosity, Iqboloy Akbutaevna Umarova

Mental Enlightenment Scientific-Methodological Journal

In today’s renewed Uzbekistan, the need to awaken historical memory, to restore forgotten national and universal values, in harmony with the spirit of the times, is permeating the worldview and consciousness of our people. Universal values: preserving and cherishing peace, preserving drinking water, not polluting the air, preserving nature, mutual solidarity, friendship, love, kindness, generosity and others. In the process of globalization, it should be and is absolutely necessary for every citizen to harmonize universal values with our national values, to preserve them and pass them on to future generations. I would like to focus on generosity and kindness among …