Digital Commons Network^™

Transcriptomic Signature-Guided Depletion Of Intermediate Alveolar Epithelial Cells Ameliorates Pulmonary Fibrosis In Mice, Fei Peng, Chun-Sun Jiang, Zhen Zheng, Shahram Aliyari, Dan Shan, Aaryan Sabharwal, Qinyan Yin, Shigeki Saito, Chao He, Ivan O Rosas, Joseph A Lasky, Victor J Thannickal, Yong Zhou

Faculty, Staff and Students Publications

Single-cell RNA sequencing (scRNA-seq) has identified intermediate epithelial states in pulmonary fibrosis, including KRT5-/KRT17+ aberrant basaloid cells in humans and Krt8+ alveolar differentiation intermediates (ADIs) in mice. Their functional contributions to fibrogenesis, however, remain unclear. Here, we introduce an RNA-sensing-dependent protein translation technology that enables selective targeting of Krt8+ ADI cells in vitro and in vivo. Transcriptomic analysis revealed Small Proline-Rich Protein 1 A (SPRR1A) mRNA as a shared marker of murine Krt8+ ADIs and human KRT5-/KRT17+ basaloid cells, distinguishing them from other lung cell populations. Using programmable RNA sensors, we demonstrated selective EGFP-labeling of Krt8+ ADI cells in vivo, …

Fragmented Foundations: Interpreter Educator Resources And Uneven Student Preparation, Kierstin S. Muroski

Journal of Interpretation

The readiness-to-work gap among graduates of signed language interpreting programs has been widely acknowledged for decades. Efforts to address the gap have primarily focused on training methods and student performance. This paper shifts the focus to interpreter educators, examining whether the inconsistencies in their awareness and use of discipline-related books may contribute to the disparate educational outcomes of students entering the workforce. Drawing on survey data from 75 interpreter educators in the United States, this study explores demographic patterns of their book awareness and usage in teaching. Results indicate that awareness and utilization of discipline-related books to support teaching are …

Defending And Challenging American Empire: The 1927-28 University Of Oregon Forensics Program World Debate Tour And The November 25, 1927, Manila "Debate Of The Century", Trond Jacobsen, David Frank

Studies in Debate and Oratory

From October 1927 through April 1928, three Oregon debaters traveled more than 25,000 miles to seventeen countries on four continents, participating in thirty-two debates and seventy-five public speaking engagements as part of the first-ever Debate World Tour. This tour was audacious, but indicative of a remarkable history of debate at Oregon. Drawing on archival materials held by the Special Collections and University Archive at the University of Oregon and other primary and contemporary materials, we document that world tour and feature a November 25, 1927, debate on Filipino independence at the Manila Opera House and the tour of America by …

The Archon, 1952 Edition, Zeta Phi Beta Sorority Incorporated

Josie Green Washington Papers

A 1952 edition pamphlet called The Archon, an official organ of the Zeta Phi Beta Sorority.

The Archon, 1951 Edition, Zeta Phi Beta Sorority Incorporated

Josie Green Washington Papers

A 1951 edition pamphlet called The Archon, an official organ of the Zeta Phi Beta Sorority.

To Extract Or Not To Extract: On What Basis Do We Make That Decision? (Part I), Ib Leth Nielsen

Taiwanese Journal of Orthodontics

The decision to remove permanent teeth is often challenging for the orthodontist, and multiple factors should be considered. The primary reason for extracting teeth is crowding, followed by aesthetic concerns, particularly the risk of creating a flat facial profile from over-retracting the front teeth. Often, the facial growth patterns are overlooked in this decision-making process. This review will explore how facial morphology, growth patterns, and maturation stages influence the extraction decision. We shall address common concerns related to extractions, such as the impact on esthetics, airways, the effect of extractions on buccal corridors, their relationship to TMJ issues, and the …

Synthesis And Characterization Of Mn4S4:Ni2S2 Chalcogenide Electrodes For Superior Supercapacitive Properties, Yasser T. Alharbi

University of Bisha Journal for Basic and Applied Sciences

The growing interest of researchers is shifted towards energy storage systems and the production of energy storage materials. In present research, an innovative Mn₄S₄:Ni₂S₂ semiconducting nanocomposite has synthesized using single source technique by fabricating di hexyldithiocarbamate ligand to further improve the efficiency of charge storing batteries. The fabricated material shown efficient optical property with direct band gap in range of 3.2–3.26eV. The crystallographic analysis examined the average crystalline size of the prepared nanocomposite particles of about 22 nm. The IR spectroscopy analysis has shown the presence of metal-sulfur bond and their peaks has …

Assessing Knowledge, Attitude, And Practice Of Diabetic Retinopathy Management Among Patients In Riyadh, Ferial M Zeried, Lulwah Mesfer Al-Haqbani, Anayochukwu Edward Anyasodor, Ezinne Ngozika, Uchechukwu L Osuagwu

University of Bisha Journal for Basic and Applied Sciences

Aim: Diabetic retinopathy (DR) is a common microvascular complication of diabetes and a leading cause of preventable vision loss. Understanding patients’ knowledge, attitudes, and practices (KAP) toward DR screening and management is critical for designing effective interventions. This study aimed to assess the KAP of individuals with diabetes regarding DR in Riyadh, Saudi Arabia.

Methods: A web-based cross-sectional survey was conducted among 535 Saudi adults with diabetes between January and April 2021. Descriptive statistics were used to summarize participant characteristics and KAP levels. Multivariate logistic regression (MLR) was performed to identify sociodemographic and clinical predictors of high KAP, with adjusted …

Cultural Influences Experienced By Self-Identified Hmong College Students, Nkaujntsa Lovy Lee

Walden Dissertations and Doctoral Studies

The purpose of this qualitative research was to explore how self-identified Hmong college students aged 18–24 perceived their culture’s influence on their academic experiences. The study examined the relationships shaping individual identity and their effects on academic pursuits. A basic qualitative inquiry approach was used to interview ten Hmong undergraduate students enrolled in colleges across the United States. Semi-structured interviews facilitated data collection guided by the ecological systems theory, while thematic analysis and inductive coding were employed to identify patterns and develop themes from the data. The themes identified in the study were family as the central influence, negotiating conflicting …

Sociodemographic And Hiv-Related Characteristics Associated With Mental Health Diagnoses Among People Living With Hiv, Monique J. Brown Ph.D., Mph, Jiayang Xiao, Xueying Yang Ph.D., Bankole Olatosi Ph.D., Sharon Weissman, Xiaoming Li Ph.D., Jiajia Zhang Ph.D.

Faculty Publications

Mental health diagnoses have been linked to poor HIV treatment outcomes and poorer quality of life among people living with HIV (PLWH). Therefore, this study aimed to investigate the association between sociodemographic and HIV-related characteristics, and common and serious mental health disorders among PLWH in South Carolina (SC). Data were obtained from the integrated system of statewide electronic health record (EHR) data in SC (2006–2019; N = 8,124). Multivariable logistic regression models were used to determine the associations between sociodemographic and HIV-related characteristics, and common mental health disorders and serious mental health disorders. Among the study population, 4% were 60 …

What Representation Looks Like: A Content Analysis Of African American Characters In Louisiana’S Young Readers’ Choice And Teen Readers’ Choice Graphic Novels, Samantha J. Green

Theses and Dissertations

The purpose of this content analysis is to show how African Americans are represented in the novels selected for the Louisiana Young Readers’ Choice and Louisiana Teen Readers’ Choice programs. Twenty-one graphic novels and one graphic story were used in this study. The primary source of data collection was analyzing the texts using the African American text features list. Findings indicated that when included, the representation of African Americans in the graphic novels was accurate and authentic. However, there was not a large number of graphic novels that have been selected for the lists. It is suggested that future research …

Repair Techniques For Acute Rupture Of The Patellar Tendon: A Systematic Review, Gaston Davis, Harrison S. Fellheimer, Christian Mccormick, Kevin B. Freedman

Rothman Institute Papers

BACKGROUND: Multiple techniques exist to repair acute tears of the patellar tendon. Surgical repair is required to reestablish full function of the extensor mechanism of the knee, and optimal results typically occur when the tear is repaired acutely.

PURPOSE: To systematically review the literature to evaluate treatment outcomes and complication rates after acute surgical repair of patellar tendon ruptures using suture anchor repair, transosseous repair, and end-to-end repair.

STUDY DESIGN: Scoping review; Level of evidence, 4.

METHODS: A systematic review was performed to analyze outcomes after patellar tendon repair in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews …

Urban Sprawl And Residential Carbon Emissions: Evidence From Indonesia And The Philippines, Yi Jiang, Taylor Lathrop, Alexander D. Rothenberg, Yao Wang

Center for Policy Research

This paper studies how neighborhood density affects residential carbon emissions, using detailed data from Indonesia and the Philippines. To address simultaneity, we instrument density with soil characteristics, and to address sorting, we control for community averages of observed characteristics. Unlike cities in developed countries, we find that density is positively correlated with residential energy use. After controlling for sorting, we find a precise null relationship between density and residential carbon emissions. Our results suggest that policies to control urban sprawl may not be successful in reducing residential carbon emissions in developing country cities.

Book Review Of Stolen Pride: Loss, Shame, And The Rise Of The Right By Arlie Russell Hochschild. New York: The New Press. 2024, Roger Clark

Sociology Between the Gaps: Forgotten and Neglected Topics

No abstract provided.

2026-01-09 Minutes Of The Executive Committee Of The Academic Senate Senate, University Of Dayton. Academic Senate. Executive Committee

ECAS Minutes

Approved minutes of a meeting of the Executive Committee of the Academic Senate of the University of Dayton.

Making Waves Podcast: Exploring Stem Through Undergraduate Voices, E. Langer, K. Sosa, N. Barber, A. Vázquez Marrero, A. Zuniga, J. Malloy, J. Gutierrez-Paiz, A. Ingraham, C. Campbell, M. Walters, A. R. Arellano

Making Waves REU

• Engage, train, and educate students in the discipline of oceanographic research and science communication.
• Provide an immersive ocean science Research Experience for Undergraduates (REU).
• Effectively communicate interdisciplinary marine science subjects.

Clinical And Dosimetric Dataset Of Time-To-Event Normal Tissue Complication Probability For Osteoradionecrosis, Natalie A West, Serageldin Kamel, Andrew Wentzel, Zaphanlene Kaffey, Moamen Abdelaal, G Elisabeta Marai, Guadalupe Canahuate, Xinhua Zhang, Melissa M Chen, Kareem A Wahid, Jillian Rigert, Kristy K Brock, Mark Chambers, Adegbenga O Otun, Ruth Aponte-Wesson, Renjie He, Mohamed A Naser, Katherine A Hutcheson, Abdallah S R Mohamed, Lisanne V Van Dijk, Amy C Moreno, Stephen Y Lai, Clifton D Fuller, Laia Humbert-Vidan

Faculty, Staff and Student Publications

Osteoradionecrosis of the jaw (ORNJ) is a radiation-induced late toxicity that can dramatically decrease patients' quality of life. Recent increases in survival rates of head and neck cancers associated with human papillomavirus (HPV) infection have resulted in a higher frequency of radiation-induced toxicities, particularly ORNJ. Recent work with Normal Tissue Complication Probability (NTCP) models and a Weibull Accelerated Failure Time (WAFT) model have further developed our understanding of ORNJ clinical/dosimetric risk factors and longitudinal features, respectively. In this data descriptor, 1129 head and neck cancer (HNC) patients received curative intent radiotherapy (RT) at MD Anderson Cancer Center and were followed …

An Integrated Single-Cell And Spatial Transcriptomic Atlas Of Thyroid Cancer Progression Identifies Prognostic Fibroblast Subpopulations, Matthew A Loberg, George J Xu, Sheau-Chiann Chen, Hua-Chang Chen, Claudia C Wahoski, Kailey P Caroland, Megan L Tigue, Heather A Hartmann, Jean-Nicolas Gallant, Courtney J Phifer, Andres A Ocampo, Dayle K Wang, Reilly G Fankhauser, Kirti A Karunakaran, Chia-Chin Wu, Maxime Tarabichi, Sophia M Shaddy, James L Netterville, Sarah L Rohde, Carmen C Solórzano, Lindsay A Bischoff, Naira Baregamian, Barbara A Murphy, Jennifer H Choe, Jennifer R Wang, Eric C Huang, Quanhu Sheng, Luciane T Kagohara, Elizabeth M Jaffee, Ryan H Belcher, Ken S Lau, Fei Ye, Ethan Lee, Vivian L Weiss

Faculty, Staff and Student Publications

Although well-differentiated thyroid carcinoma (WDTC) is characterized by a robust treatment response, aggressive subtypes, such as anaplastic thyroid carcinoma (ATC), remain highly lethal. To understand thyroid cancer evolution in both children and adults, we analyzed single-cell transcriptomes of 423,733 cells from 81 samples and spatially resolved key tumor and microenvironment populations across 28 tumors with spatial transcriptomics, including rare and unique composite WDTC/ATC tumors and pediatric diffuse sclerosing thyroid carcinomas. Additionally, we identified gene signatures of stromal cell populations in 5 large thyroid cancer bulk RNA-sequencing cohorts. Through this multi-institutional effort, we defined a population of POSTN+ myofibroblast cancer-associated fibroblasts …

Jiving With Llms: Assessing First Year Students’ Computer Programming Self Efficacy After Reading Code With Llms, Michelle Jarvie-Eggart, Joseph Roy Teahen, Daniel T. Masker, Jose Padilla, Leo C. Ureel Ii, Laura E. Brown, Scott Pomerville, Jon Sticken

Michigan Tech Publications

This study investigated the impact of leveraging generative artificial intelligence (GenAI) to assist 1st-year engineering and computer science (CS) students in reading code in a new (to them) language. Students were asked to comment code in FORTRAN. They were then asked to run the code through ChatGPT-4.0 for its comments and reflect on what they learned from the experience. Participants completed survey items from Ramalingam and Wiedenbeck’s Computer Programming Self-Efficacy Scale (CPSES) prior to and after the intervention. Additional open-ended reflective (qualitative) questions were added to the quantitative questions in the postintervention questionnaire. This study documents increases in self-efficacy for …

Prognostic Value Of Baseline Qfr In Single-Vessel Intermediate Coronary Stenosis, Yanfeng Lu, Abdulrahman Alqazzaz, Jasmine Bao, Gary S. Mintz, Jiahao Feng, Yong Zhang, Shanshan Gao, Qiang Song, Feifei Ning, Xin Huang, Ning Guo

Student Papers, Posters & Projects

BACKGROUND AND OBJECTIVES: The prognostic value of baseline Quantitative Flow Ratio (QFR) in real-world patients remains unclear. This study aimed to evaluate the prognostic value of baseline QFR and its three-tier model-low, grey-zone, and high QFR-in patients with single-vessel intermediate stenosis.

METHODS: This retrospective study included 478 patients with QFR between 0.70 and 0.90 who underwent coronary angiography between May and June 2023. Patients were stratified into Low (0.70-0.74), Grey-Zone (0.75-0.85), and High (0.86-0.90) QFR groups. The primary endpoint was major adverse cardiac events (MACE); the key secondary endpoint was target vessel failure (TVF). Kaplan-Meier and Cox proportional hazards models …

Mobile Apps For Psychotic Disorders: A Systematic Review Protocol, Ananya Ananthakrishnan, Aditya Narain Sharma, David Anderson, Rohit Shankar, Edward Meinert

Peninsula Medical School

BackgroundEarly intervention for psychotic spectrum disorders can improve long-term outcomes, but service availability and quality can vary globally. Mobile apps have the potential to provide personalised and accessible support for people with psychotic disorders via features such as symptom monitoring, medication reminders, and self-management interventions. Existing reviews have provided an overview of such apps and their feasibility but lack a synthesis of their efficacy, safety, and acceptability. Addressing this gap would guide future app designs and facilitate their implementation by informing clinical and policy decisions. The purpose of this systematic review will be to synthesise the evidence about existing mobile …

The Employment Situation Of Veterans: December 2025, Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

In December 2025, U.S. unemployment held steady at 4.6%, while veteran unemployment rose from 3.4% to 3.9%. Post-9/11 veterans saw a sharper increase to 5.1%. Younger veterans (18–24) faced the highest rate at 14.8%, far above nonveterans (8.4%). Female veteran unemployment jumped to 4.5%, exceeding nonveteran women (3.8%), while male veterans remained slightly below nonveteran men. Racial trends varied: Black veterans’ unemployment fell to 6.6%, below nonveterans, while Hispanic veterans rose to 4.3%. Employment gains occurred in food service, healthcare, and social assistance, while retail declined. Overall, veteran unemployment trends diverged significantly by age, gender, and ethnicity.

Primary Cortical Neurons Precipitate And Extrude Large Mitochondria-Associated Calcium-Phosphate Sheets With A Bone-Precursor-Like Ultrastructure, Erik D Anderson, Christopher A Cronkite, Philip R Baldwin, Carlota P Abella, Joseph G Duman, Ashleigh N Simmonds, M Neal Waxham, Kimberley F Tolias, Steven J Ludtke

Faculty, Staff and Students Publications

Calcium-phosphate (CaP) is a ubiquitous inorganic compound that plays an important structural role in healthy bone and teeth formation, but its pathologic buildup can occur in dyshomeostatic calcium disorders like Alzheimer's disease and Leigh syndrome. The nexus of pathologic extracellular CaP in the nervous system is not well understood, but prior evidence suggests mitochondria could be a source. We have observed mitochondria-sized sheet-like CaP aggregates within functional wild type cortical neuron cultures at 1 and 20 days in vitro. Neurons were extracted from embryonic day 18 (E18) rat embryos following standard protocols to study neuronal structure and function. We have …

Maternal Immunization With Vp8* Mrna Vaccine Yields Superior Passive Transfer Of Rotavirus-Neutralizing Antibodies To Foals, Karin E R Borba, Rebecca M Legere, Nathan M Canaday, Jill W Skrobarczyk, Zachary W T Arnold, Elena Cotton-Betteridge, Cristina Poveda, Michael F Criscitiello, Angela I Bordin, Luc R Berghman, Jeroen B K Pollet, Noah D Cohen

Faculty, Staff and Students Publications

Background: Despite the availability of a killed whole-virus (KV) vaccine, diarrhea caused by equine rotavirus group A (ERVA) remains a significant health concern for foals in the United States. The vaccine is administered to pregnant mares, with foals protected by passive transfer of colostral antibodies. However, KV-induced immunity is only partially protective and maternal antibody levels in foals are often low and wane rapidly. To address these limitations, we developed a mRNA-based ERVA vaccine encoding the highly conserved VP8* protein to evaluate whether it can provide improved immune protection.

Methods: Pregnant mares (n = 12 per group) were …

Considering What Counts: Are Urban Homicide Rates Rising Or Falling?, Joel Best, Keith R. Johnson

Numeracy

Recent commentary has featured a debate over whether urban homicide rates are rising or falling. This debate illustrates the complexities of trying to convey the significance of statistical data.

Teaching Numeracy For Social Justice: Educational Equity, Esther Isabelle Wilder, Crystal C. Rodriguez, Caterina Shost, Eduardo Vianna, Frank Wang

Numeracy

The special collection, “Teaching Numeracy for Social Justice: Educational Equity,” focuses on how quantitative reasoning (QR) can function as a vehicle for equity, empowerment, and democratic participation. Building on a longstanding tradition that treats numeracy as inseparable from social justice, these contributions highlight how progressive pedagogies (e.g., active learning, authentic research, and equity-oriented assessment) have the potential to broaden access for students historically excluded from quantitative fields. The studies span a variety of conceptual frameworks, introductory and advanced quantitative instruction, and interdisciplinary applications, showcasing how inclusive QR practices can build confidence, agency, and real-world understanding. These articles demonstrate that when …

A Study Of The Impacts Of Infusing Data Analysis And Research In An Interdisciplinary Environmental Economics Course, Sean P. Macdonald

Numeracy

This paper explores the impacts of introducing quantitative literacy skills in an interdisciplinary Environmental Economics course typically taught as an issues and policy course without a quantitative component. The study examines the effects of infusing an engaging, student-selected data collection and analysis assignment on students' quantitative reasoning skills, as well as their interest in and attitudes about data analysis and quantitative information. Using data gathered from a set of pre- and post-assessment questions designed to measure changes in quantitative reasoning skills and attitudes, the findings point to significant attitudinal impacts, gains, but smaller, insignificant gains in quantitative reasoning skills.

Quantitative Reasoning In Calculus Iii: Advancing Student Engagement, Confidence, And Aspirations At An Hsi, Tanvir Prince

Numeracy

This study examines the impact of integrating Quantitative Reasoning (QR) into a Calculus III course at a Hispanic-Serving Institution (HSI) on student engagement, confidence, and aspirations. The course is offered at Hostos Community College in the South Bronx. It incorporated QR-focused projects on economic inequality, environmental pollution, and access to healthcare. These projects allowed students to apply advanced calculus concepts to real-world social issues. A pre- and post-survey design was employed to assess changes in students’ mathematical confidence, perceptions of relevance, and career and educational goals. Results showed statistically significant gains in confidence and in the belief that advanced math …

A Comparison Of First- And Continuing-Generation Students Completing A Project-Based Introductory Statistics Course, Susan A. Dumais, Naomi J. Spence, Lisa Dierker

Numeracy

Traditional introductory statistics courses that focus on techniques are not engaging for many college students; this may be especially true for first-generation college students, who generally have more difficulty engaging in the college environment than continuing-generation students. We study first-generation college students’ experiences in a course-based undergraduate research experience called Passion-Driven Statistics. Passion-Driven Statistics is a multidisciplinary, project-based introductory statistics course where students develop their own research topics, analyze publicly available quantitative data, and focus on conceptual understanding of statistics rather than hand calculations. Using pre-course and post-course surveys from students taking Passion-Driven Statistics in colleges throughout the United States, …

Toward Fairer And More Equitable Numeracy Measurement: Improvements To The Quantitative Reasoning For College Science Assessment, Vonna L. Hemmler, Isaac Rosenthal, Kate Follette, Catherine Sarosi, Erin Galyen, Sanlyn Buxner, Jackson Carter, Samantha Maynard, Sarah Bunnell

Numeracy

Numeracy has become an increasingly important 21st-century skill that, due to the relationship between math and science, is often formally developed at the college level in general education science courses. These courses serve a diverse group of students, many of whom have historically experienced science teaching, curriculum, and assessment on the margins. The well-documented biases of assessments in particular against Individuals of Color (IoC) have inspired us to approach numeracy for social justice in our work from this angle, and in this paper, we detail our efforts to revise our validated numeracy assessment to ensure it more fairly and equitably …