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Professional Perspectives On Bilingualism In Persons With Autism Spectrum Disorder: A Pilot Study, Rosa N. Benavidez Saldivar, Jessica R. Stewart, Ruth Crutchfield, Roy K. Chen, Lily Puente Nov 2022

Professional Perspectives On Bilingualism In Persons With Autism Spectrum Disorder: A Pilot Study, Rosa N. Benavidez Saldivar, Jessica R. Stewart, Ruth Crutchfield, Roy K. Chen, Lily Puente

Communication Sciences & Disorders Faculty Publications

Purpose: The present study examined the perspectives of professionals regarding bilingualism and ASD.

Methods: A total of 27 professionals participated in this study. Data was collected via an online survey. The survey was designed based on a literature review and consultation with a team of experts in the field of ASD. Information relating to demographic information, professional practice information, and perspectives of bilingualism and ASD was collected.

Results: Professionals participating in the present study were most likely to agree with the statement, “A child with ASD from a bilingual household is able to understand both languages” and least likely …


Passing The Camel Through The Eye Of The Needle: Documenting A Culture Of Teacher Praxis At An Affluent Catholic High School, Nicholas S. Vasiliades Nov 2022

Passing The Camel Through The Eye Of The Needle: Documenting A Culture Of Teacher Praxis At An Affluent Catholic High School, Nicholas S. Vasiliades

Theses & Dissertations

There is a dearth of research concerning critical communities of learning in affluent Catholic high schools. This ethnography captured a culture of praxis developed through the process of five educators team-teaching an interdisciplinary AP Seminar course at St. Aurelia’s Catholic High School on Long Island, New York, from September 2021 to February 2022, with a particular emphasis on Catholic Social Teaching as an authentic avenue for the implementation of social justice education. Observations, one-to-one interviews, focus group discussions, peer-observations, and journals were recorded and coded to explore the facets of the team culture engaged in this collaborative endeavor. A culture …


Seeing The World Through Their Eyes: The Impact Of Place Attachment On Teachers' Understanding Of Worldviews, Kathleen Murray Nov 2022

Seeing The World Through Their Eyes: The Impact Of Place Attachment On Teachers' Understanding Of Worldviews, Kathleen Murray

Theses & Dissertations

Over the past 20 years, Long Island, New York, has seen an increase in linguistic and racial diversity within its schools. The growth in linguistic diversity has brought with it an increase in English language learners (ELLs), representing almost a 50% increase since 2012. As the ELL population has grown, so has the achievement gap between ELLs and their non-ELL peers. The current teaching staff on Long Island does not match the diversity of its student population. Prior research has shown that the cultural mismatch between the teachers and students is one contributing factor to the aforementioned achievement gap. In …


Chronic Kidney Disease Patients' Experiences In The Decision Making Process: The Relationship Between Personal Characteristics And Decisional Self-Efficacy On Decisional Conflict And The Dialysis Decision In Patients Who Participated In Shared Decision Making, Lincy Jojan Nov 2022

Chronic Kidney Disease Patients' Experiences In The Decision Making Process: The Relationship Between Personal Characteristics And Decisional Self-Efficacy On Decisional Conflict And The Dialysis Decision In Patients Who Participated In Shared Decision Making, Lincy Jojan

Theses & Dissertations

Patients with End Stage Renal Disease (ESRD) experience a complex and stressful decision making when comes to dialysis modality selection. There are pros and cons to both hemodialysis (HD) and peritoneal dialysis (PD). Patients are often uncertain as to which one is the best modality for them. This decisional conflict increases the likelihood of making a decision that is not based on the patient’s values or preferences and may result in undesirable post-decisional consequences. Purpose The purpose of this study was to explore Chronic Kidney Diseases (CKD) patients' experiences regarding their decision making process in selecting a dialysis modality. The …


Api-Related Developer Information Needs In Stack Overflow, Mingwei Liu, Xin Peng, Andrian Marcus, Shuangshuang Xing, Christoph Treude, Chengyuan Zhao Nov 2022

Api-Related Developer Information Needs In Stack Overflow, Mingwei Liu, Xin Peng, Andrian Marcus, Shuangshuang Xing, Christoph Treude, Chengyuan Zhao

Research Collection School Of Computing and Information Systems

Stack Overflow (SO) provides informal documentation for APIs in response to questions that express API related developer needs. Navigating the information available on SO and getting information related to a particular API and need is challenging due to the vast amount of questions and answers and the tag-driven structure of SO. In this paper we focus on identifying and classifying fine-grained developer needs expressed in sentences of API-related SO questions, as well as the specific information types used to express such needs, and the different roles APIs play in these questions and their answers. We derive a taxonomy, complementing existing …


Targeted Sanctions Against Human Rights Violators: A Question Of Efficacy, Jennifer F. Dillard Nov 2022

Targeted Sanctions Against Human Rights Violators: A Question Of Efficacy, Jennifer F. Dillard

Honors College Theses

Human rights violations occur all too frequently, with authoritarian regimes at the forefront of abuses. Countries that respect human rights engage in various initiatives, one such example being targeted sanctions to try and stem the tide of human suffering at the hands of unscrupulous dictators. Currently, Uyghurs are victims of genocide in China, dissidents in countries such as Russia and Belarus are falsely imprisoned, and individuals in Saudi Arabia are persecuted and imprisoned solely for advocating for freedom of speech and equality for women. Each of these countries have been the subject of sanctions. This paper seeks to answer the …


Hiring Decisions: Impacts Of Applicant Gender And Social Media Presence, Alicia Ostrowski Nov 2022

Hiring Decisions: Impacts Of Applicant Gender And Social Media Presence, Alicia Ostrowski

Honors College Theses

Studies show that hiring decisions can be influenced by an applicant’s social media profile (Broughton et al., 2013) as well as their gender (Garcia-Retamero & Lopez-Zafra, 2009). Women, compared to men, are more likely to face hiring discrimination (Garcia-Retamero & Lopez-Zafra, 2009) and many hiring managers tend to look at an applicant’s social media profiles for additional information during the hiring process (Broughton et al., 2013). There is a lack of substantial research on the combination of these two factors. This study examined the effects of gender and social media type on hiring decisions.


Towards Automated Safety Vetting Of Smart Contracts In Decentralized Applications, Yue Duan, Xin Zhao, Yu Pan, Shucheng Li, Minghao Li, Fengyuan Xu, Mu Zhang Nov 2022

Towards Automated Safety Vetting Of Smart Contracts In Decentralized Applications, Yue Duan, Xin Zhao, Yu Pan, Shucheng Li, Minghao Li, Fengyuan Xu, Mu Zhang

Research Collection School Of Computing and Information Systems

We propose VetSC, a novel UI-driven, program analysis guided model checking technique that can automatically extract contract semantics in DApps so as to enable targeted safety vetting. To facilitate model checking, we extract business model graphs from contract code that capture its intrinsic business and safety logic. To automatically determine what safety specifications to check, we retrieve textual semantics from DApp user interfaces. To exclude untrusted UI text, we also validate the UI-logic consistency and detect any discrepancies. We have implemented VetSC and applied it to 34 real-world DApps. Experiments have demonstrated that VetSC can accurately interpret smart contract code, …


Towards Automated Safety Vetting Of Smart Contracts In Decentralized Applications, Yue Duan, Xin Zhao, Yu Pan, Shucheng Li, Minghao Li, Fengyuan Xu, Mu Zhang Nov 2022

Towards Automated Safety Vetting Of Smart Contracts In Decentralized Applications, Yue Duan, Xin Zhao, Yu Pan, Shucheng Li, Minghao Li, Fengyuan Xu, Mu Zhang

Research Collection School Of Computing and Information Systems

We propose VetSC, a novel UI-driven, program analysis guided model checking technique that can automatically extract contract semantics in DApps so as to enable targeted safety vetting. To facilitate model checking, we extract business model graphs from contract code that capture its intrinsic business and safety logic. To automatically determine what safety specifications to check, we retrieve textual semantics from DApp user interfaces. To exclude untrusted UI text, we also validate the UI-logic consistency and detect any discrepancies. We have implemented VetSC and applied it to 34 real-world DApps. Experiments have demonstrated that VetSC can accurately interpret smart contract code, …


The Past, Present, And Future Of China-Related Accounting Research, Qiang Cheng, Luzi Hail, Gwen Yu Nov 2022

The Past, Present, And Future Of China-Related Accounting Research, Qiang Cheng, Luzi Hail, Gwen Yu

Research Collection School Of Accountancy

This discussion makes several observations regarding the past 25 years of China-related accounting research reviewed in Lennox and Wu (2022). First, we discuss factors of supply and demand that led to the rise of China-related studies and how this growth has contributed to the internationalization of accounting research. We note that the taxonomy of the literature by geographic region rather than topic or methodology is unusual and makes it difficult to formulate a common framework that would help organize the many contributions. Next, we distill distinct patterns in authorship, choice of topics, and asserted contributions of China-related studies. Studies are …


Introducing A Model For How Knowledge-Driven Agile Innovation Can Drive Digital Transformation In Firms, Lipika Bhattacharya, Clarence Goh, Gary Pan Nov 2022

Introducing A Model For How Knowledge-Driven Agile Innovation Can Drive Digital Transformation In Firms, Lipika Bhattacharya, Clarence Goh, Gary Pan

Research Collection School Of Accountancy

Digital transformation often arises from the distribution of tasks among interdisciplinary teams of experts. One important factor that determines the success of digital transformation relates to an organization’s ability to innovate in an agile manner. In this article, we identify key drivers of digital transformation, which include organizational agility, knowledge management and innovation. Another crucial aspect of knowledge management relates to the coordination of knowledge. It is important for organizations to focus on knowledge coordination because the lack of coordination can dissuade them from meeting the demands for flexibility and speed during digital transformation, thereby negating the potential benefits from …


Family Still Matters: Human Social Motivation Across 42 Countries During A Global Pandemic, Cari M. Pick, Et. Al. Nov 2022

Family Still Matters: Human Social Motivation Across 42 Countries During A Global Pandemic, Cari M. Pick, Et. Al.

Research Collection School of Social Sciences

The COVID-19 pandemic caused drastic social changes for many, including separation from friends and coworkers, enforced close contact with family, reductions in mobility, and a number of other health-related precautions. Here we assess the extent to which people’s evolutionarilyrelevant basic motivations and goals—their fundamental social motives—might have been affected. To address this question, we gathered data on these motives in 42 countries (N=15,915) in two waves, including 19 countries (N=10,907) for which data were gathered both before and during the pandemic (Pre-pandemic wave: 32 countries, N=8998; 3302 male, 5585 female; Mage=24.43, SD=7.91; Mid-pandemic wave: 29 countries, N=6917; 2249 male, 4218 …


Intensive Family Observations: A Methodological Guide, Annette Lareau, Aliya Hamid Rao Nov 2022

Intensive Family Observations: A Methodological Guide, Annette Lareau, Aliya Hamid Rao

Research Collection School of Social Sciences

There is a dearth of methodological guidance on how to conduct participant observation in private spaces such as family homes. Yet, participant observations can provide deep and valuable data about family processes. This article draws on two ethnographic studies of family life in which researchers conduct in-depth interviews, recruit families, and ultimately enter the family as a quasi-stranger for daily observations lasting a fixed period (e.g., three weeks). We term this approach "intensive family observations." Here, we provide concrete methodological advice for this method, beginning with guidelines for recruitment and gaining consent. We also discuss logistics of conducting family observation …


The Privacy Of Hak-Shing William Tam: Imagining Asian Families In California’S Proposition 8, Justin Kh Tse Nov 2022

The Privacy Of Hak-Shing William Tam: Imagining Asian Families In California’S Proposition 8, Justin Kh Tse

Research Collection School of Social Sciences

In terms of Asian Americans whose reputations have been popularly derided, the concerned parent activist Hak-Shing William Tam perhaps ranks among the top. Tam was a citizen proponent of California’s Proposition 8 in 2008 to amend the state constitution to ban same-sex marriage and became a hostile witness for the plaintiffs in the subsequent 2010 lawsuit to overturn the amendment, Perry v. Schwarzenegger. In this paper, I explore Tam’s claim to privacy in his understanding of these events, both in terms of his sexualized imagination of liberal civil society and his suffering from what he understood as violations of his …


Infrastructure's (Supra)Sacralizing Effects: Contesting Littoral Spaces Of Fishing, Faith, And Futurity Along Sri Lanka's Western Coastline, Orlando Woods Nov 2022

Infrastructure's (Supra)Sacralizing Effects: Contesting Littoral Spaces Of Fishing, Faith, And Futurity Along Sri Lanka's Western Coastline, Orlando Woods

Research Collection School of Social Sciences

This paper explores the ways in which infrastructural development can cause the sacred to become a source of political legitimacy, and sacred authority to become a politically charged construct. For resource-dependent communities, the ecological damage caused by infrastructural development can cause ostensibly profane issues to be imbued with sacred meaning and value. With sacralization comes the expectation that figures of sacred authority will campaign for justice on behalf of the communities that they represent. However, when the authority evoked comes from outside the boundaries of institutionalized religion, processes of suprasacralization come into play. By exploring infrastructure’s (supra)sacralizing effects, I demonstrate …


Does Trait Self-Esteem Serve As A Resilience Factor In Maintaining Affective Well-Being? Findings From Daily Diary Studies In Singapore And The United States, Matthew H. S. Ng, Verity Yu Qing Lua, Nadyanna M. Majeed, Andree Hartanto Nov 2022

Does Trait Self-Esteem Serve As A Resilience Factor In Maintaining Affective Well-Being? Findings From Daily Diary Studies In Singapore And The United States, Matthew H. S. Ng, Verity Yu Qing Lua, Nadyanna M. Majeed, Andree Hartanto

Research Collection School of Social Sciences

Research suggests that self-esteem could be a protective factor in stressful or unfavorable situations. However, little research has been done on the buffering role of self-esteem in the context of daily stressors on affective reactivity. Three daily diary studies (of which two were conducted in Singapore and one in the United States) were carried out to examine this relationship. In all three studies, trait self-esteem was measured at baseline. Subsequently, daily assessment was conducted on exposure to daily stressors, and positive and negative affect for seven to eight days. Multilevel modeling showed that trait self-esteem did not moderate the relationship …


Young Singaporeans Abroad And Their Misguided Sense Of Superiority Towards S-E Asia, Lily Kong Nov 2022

Young Singaporeans Abroad And Their Misguided Sense Of Superiority Towards S-E Asia, Lily Kong

Research Collection School of Social Sciences

In a commentary, SMU President and Lee Kong Chian Chair Professor of Social Sciences Lily Kong –whose research has focused over the decades on social and cultural change in Asian cities – discussed why young Singaporeans can have a misguided sense of superiority towards South-east Asia when they venture abroad. She explained how this could blind them to their neighbours’ hidden strengths. Prof Kong also shared that SMU has sought to actively vest in its students a sound appreciation of growth in Asia. To support this endeavour, the University is launching a series of overseas centres in selected South-east Asian …


Deliberate Errors Promote Meaningful Learning, Sarah Shi Hui Wong, Stephen Wee Hun Lim Nov 2022

Deliberate Errors Promote Meaningful Learning, Sarah Shi Hui Wong, Stephen Wee Hun Lim

Research Collection School of Social Sciences

Our civilization recognizes that errors can be valuable learning opportunities, but for decades, they have widely been avoided or, at best, allowed to occur as serendipitous accidents. The present research tested whether greater learning success could paradoxically be achieved through making errors by intentional design, relative to traditional errorless learning methods. We show that deliberately committing and correcting errors even when one knows the correct answers enhances learning—a counterintuitive phenomenon that we termed the derring effect. Across two experiments (N = 160), learners engaged in open-book study of scientific expository texts and were then tested on their retention and higher-order …


Personal Comfort Models Based On A 6‐Month Experiment Using Environmental Parameters And Data From Wearables, Federico Tartarini, Stefano Schiavon, Matias Quintana, Clayton Miller Nov 2022

Personal Comfort Models Based On A 6‐Month Experiment Using Environmental Parameters And Data From Wearables, Federico Tartarini, Stefano Schiavon, Matias Quintana, Clayton Miller

Research Collection College of Integrative Studies

Personal thermal comfort models are a paradigm shift in predicting how building occupants perceive their thermal environment. Previous work has critical limitations related to the length of the data collected and the diversity of spaces. This paper outlines a longitudinal field study comprising 20 participants who answered Right-Here-Right-Now surveys using a smartwatch for 180 days. We collected more than 1080 field-based surveys per participant. Surveys were matched with environmental and physiological measured variables collected indoors in their homes and offices. We then trained and tested seven machine learning models per participant to predict their thermal preferences. Participants indicated 58% of …


Cry Wolf, Olivia Claire Acosta Nov 2022

Cry Wolf, Olivia Claire Acosta

Electronic Theses and Dissertations

Cry Wolf is a confessional poetry collection told in three sections about at-work stalking. This collection also alludes to the Brothers Grimm fairytale, The Little Red Riding Hood. The sections of Cry Wolf include “The Wolf,” which introduces the speaker’s discovery of work-related stalking. The second section, entitled “The Fur,” is where the speaker empowers themselves to file a Title IX report about this dilemma, and Red cloaks herself in the wolf’s skin. The final portion of the collection, entitled “Red’s Home,” gives the audience a view of the speaker's self-love as they maintain it through trauma. This section also …


Association Of Atrial Septal Aneurysm And Shunt Size With Stroke Recurrence And Benefit From Patent Foramen Ovale Closure, Jean-Louis Mas, Jeffrey L Saver, Scott E Kasner, Jason Nelson, John D Carroll, Gilles Chatellier, Geneviève Derumeaux, Anthony J Furlan, Howard C Herrmann, Peter Jüni, Jong S Kim, Benjamin Koethe, Pil Hyung Lee, Benedicte Lefebvre, Heinrich P Mattle, Bernhard Meier, Mark Reisman, Richard W Smalling, Lars Sondergaard, Jae-Kwan Song, David E Thaler, David M Kent Nov 2022

Association Of Atrial Septal Aneurysm And Shunt Size With Stroke Recurrence And Benefit From Patent Foramen Ovale Closure, Jean-Louis Mas, Jeffrey L Saver, Scott E Kasner, Jason Nelson, John D Carroll, Gilles Chatellier, Geneviève Derumeaux, Anthony J Furlan, Howard C Herrmann, Peter Jüni, Jong S Kim, Benjamin Koethe, Pil Hyung Lee, Benedicte Lefebvre, Heinrich P Mattle, Bernhard Meier, Mark Reisman, Richard W Smalling, Lars Sondergaard, Jae-Kwan Song, David E Thaler, David M Kent

Faculty, Staff and Student Publications

IMPORTANCE: The Patent Foramen Ovale (PFO)-Associated Stroke Causal Likelihood classification system combines information regarding noncardiac patient features (vascular risk factors, infarct topography) and PFO features (shunt size and presence of atrial septal aneurysm [ASA]) to classify patients into 3 validated categories of responsiveness to treatment with PFO closure. However, the distinctive associations of shunt size and ASA, alone and in combination, have not been completely delineated.

OBJECTIVE: To evaluate the association of PFO closure with stroke recurrence according to shunt size and/or the presence of an ASA.

DESIGN, SETTING, AND PARTICIPANTS: Pooled individual patient data from 6 randomized clinical trials …


Assessing Urinary Phenol And Paraben Mixtures In Pregnant Women With And Without Gestational Diabetes Mellitus: A Case-Control Study, Wei-Jen Chen, Candace Robledo, Erin M. Davis, Jean R. Goodman, Chao Xu, Jooyeon Hwang, Amanda E. Janitz, Tabitha Garwe, Antonia M. Calafat, Jennifer D. Peck Nov 2022

Assessing Urinary Phenol And Paraben Mixtures In Pregnant Women With And Without Gestational Diabetes Mellitus: A Case-Control Study, Wei-Jen Chen, Candace Robledo, Erin M. Davis, Jean R. Goodman, Chao Xu, Jooyeon Hwang, Amanda E. Janitz, Tabitha Garwe, Antonia M. Calafat, Jennifer D. Peck

School of Medicine Publications

Prior studies have identified the associations between environmental phenol and paraben exposures and increased risk of gestational diabetes mellitus (GDM), but no study addressed these exposures as mixtures. As methods have emerged to better assess exposures to multiple chemicals, our study aimed to apply Bayesian kernel machine regression (BKMR) to evaluate the association between phenol and paraben mixtures and GDM.

This study included 64 GDM cases and 237 obstetric patient controls from the University of Oklahoma Medical Center. Mid-pregnancy spot urine samples were collected to quantify concentrations of bisphenol A (BPA), benzophenone-3, triclosan, 2,4-dichlorophenol, 2,5-dichlorophenol, butylparaben, methylparaben, and propylparaben. Multivariable …


Impact Of Ethnicity On Parental Health Outcomes And Experiences After Paediatric Intensive Care Unit Discharge: A Mixed-Methods Systematic Review, Pei Fen Poh, Matthew C. Carey, Jan Hau Lee, Joseph C. Manning, Jos M. Latour Nov 2022

Impact Of Ethnicity On Parental Health Outcomes And Experiences After Paediatric Intensive Care Unit Discharge: A Mixed-Methods Systematic Review, Pei Fen Poh, Matthew C. Carey, Jan Hau Lee, Joseph C. Manning, Jos M. Latour

School of Nursing and Midwifery

The impact of ethnicity on parental health outcome after paediatric intensive care unit (PICU) discharge remains unclear. Thirteen medical and healthcare databases, unpublished studies and grey literature were searched up to November 5, 2021. We performed a mixed-method systematic review to understand the impact of ethnicity on parental outcomes after PICU discharge, including eight quantitative and eight qualitative studies. Among 1529 parents included, 1064 (72%) were White. Higher prevalence of post-traumatic stress disorder was seen in Black parents (17% White vs 36% Black, p = .03). Latino ethnicity was found to have protective effect against anxiety as compared to White …


Evidence For The Effects Of Decommissioning Man-Made Structures On Marine Ecosystems Globally: A Systematic Map, Anaëlle J. Lemasson, Paul J. Somerfield, Michaela Schratzberger, Caroline Louise Mcneill, Joana Nunes, Christine Pascoe, Stephen C.L. Watson, Murray S.A. Thompson, Elena Couce, Antony M. Knights Nov 2022

Evidence For The Effects Of Decommissioning Man-Made Structures On Marine Ecosystems Globally: A Systematic Map, Anaëlle J. Lemasson, Paul J. Somerfield, Michaela Schratzberger, Caroline Louise Mcneill, Joana Nunes, Christine Pascoe, Stephen C.L. Watson, Murray S.A. Thompson, Elena Couce, Antony M. Knights

School of Biological and Marine Sciences

Background: Many marine man-made structures (MMS), such as oil and gas platforms or offshore wind turbines, are nearing their ‘end-of-life’ and require decommissioning. Limited understanding of MMS decommissioning effects currently restricts the consideration of alternative management possibilities, often leaving complete removal as the only option in certain parts of the world. This evidence-base describes the ecosystem effects of marine MMS whilst in place and following cessation of operations, with a view to informing decision-making related to their potential decommissioning. Method: The protocol used to create this map was published a priori. Systematic searches of published, literature in English were conducted …


Social Ecological Influences On Treatment Decision-Making In Men Diagnosed With Low Risk, Localised Prostate Cancer, Megan Mcintosh, Melissa J. Opozda, Camille E. Short, Daniel A. Galvão, Rebecca Tutino, Michael Diefenbach, Behfar Ehdaie, Christian Nelson Nov 2022

Social Ecological Influences On Treatment Decision-Making In Men Diagnosed With Low Risk, Localised Prostate Cancer, Megan Mcintosh, Melissa J. Opozda, Camille E. Short, Daniel A. Galvão, Rebecca Tutino, Michael Diefenbach, Behfar Ehdaie, Christian Nelson

Research outputs 2022 to 2026

Objective: Individuals diagnosed with low risk, localised prostate cancer (PCa) face a difficult decision between active surveillance (AS) and definitive treatment. We aimed to explore perceived influences on treatment decision-making from the patient and partner's perspectives. Methods: Patients (and partners) who met AS criteria and had chosen their treatment were recruited. Semi-structured individual interviews were conducted via telephone to explore experiences of diagnosis, impact on patient lifestyle, experiences with physicians, treatment preferences/choice, treatment information understanding and needs, and overall decision-making process. Interviews were audio recorded, transcribed verbatim, and analysed using Reflexive Thematic Analysis. Results: Twenty-four male patients (18 chose AS) …


Discovery Of Two Inhibitors Of The Type Iv Pilus Assembly Atpase Pilb As Potential Antivirulence Compounds, Keane J. Dye, Nancy J. Vogelaar, Megan O'Hara, Pablo Sobrado, Webster Santos, Paul R. Carlier, Zhaomin Yang Nov 2022

Discovery Of Two Inhibitors Of The Type Iv Pilus Assembly Atpase Pilb As Potential Antivirulence Compounds, Keane J. Dye, Nancy J. Vogelaar, Megan O'Hara, Pablo Sobrado, Webster Santos, Paul R. Carlier, Zhaomin Yang

Chemistry Faculty Research & Creative Works

With the pressing antibiotic resistance pandemic, Anti virulence has been increasingly explored as an alternative strategy against bacterial infections. The bacterial type IV pilus (T4P) is a well-documented virulence factor and an attractive target for small molecules for Anti virulence purposes. The PilB ATPase is essential for T4P biogenesis because it catalyzes the assembly of monomeric pilins into the polymeric pilus filament. Here, we describe the identification of two PilB inhibitors by a high-throughput screen (HTS) in vitro and their validation as effective inhibitors of T4P assembly in vivo. We used Chloracidobacterium thermophilum PilB as a model enzyme to optimize …


Recipegen++: An Automated Trigger Action Programs Generator, Imam Nur Bani Yusuf, Diyanah Abdul Jamal, Lingxiao Jiang, David Lo Nov 2022

Recipegen++: An Automated Trigger Action Programs Generator, Imam Nur Bani Yusuf, Diyanah Abdul Jamal, Lingxiao Jiang, David Lo

Research Collection School Of Computing and Information Systems

Trigger Action Programs (TAPs) are event-driven rules that allow users to automate smart-devices and internet services. Users can write TAPs by specifying triggers and actions from a set of predefined channels and functions. Despite its simplicity, composing TAPs can still be challenging for users due to the enormous search space of available triggers and actions. The growing popularity of TAPs is followed by the increasing number of supported devices and services, resulting in a huge number of possible combinations between triggers and actions. Motivated by such a fact, we improve our prior work and propose RecipeGen++, a deep-learning-based approach that …


Basalt Fibers For Underwater Fatigue Repair Of Steel Panels, Guillermo Riveros, Emad M. Hassan, Lauren Hudak, Hussam Mahmoud Nov 2022

Basalt Fibers For Underwater Fatigue Repair Of Steel Panels, Guillermo Riveros, Emad M. Hassan, Lauren Hudak, Hussam Mahmoud

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Fatigue damage is a major threat to the safety and integrity of many steel structures. Steel hydraulic structures (SHS), in particular, experience fatigue loading during operation and are exposed to harsh environmental conditions that can further reduce fatigue life through mechanisms. The traditional inspection and repair process for SHS is time-consuming and leads to economic losses. Studies investigating the behavior and advantages of using bonded carbon fiber-reinforced polymer (CFRP) to repair fatigue cracks in SHS are lacking. The main objectives of this study are to increase the bonding of CFRP, investigate the effectiveness of different fiber-reinforced polymers, and test different …


Addictive Social Media Use: Examination Of The Psychometric Properties Of The Arabic Bergen Social Media Addiction Scale And The Mediational Role Of Sense Of Control In The Relationship Between Depression And Social Media Addiction, Louis J. Fourie Nov 2022

Addictive Social Media Use: Examination Of The Psychometric Properties Of The Arabic Bergen Social Media Addiction Scale And The Mediational Role Of Sense Of Control In The Relationship Between Depression And Social Media Addiction, Louis J. Fourie

Theses

The period of COVID-19 has proven to be a turbulent period where extreme psychological trends can be examined due to lockdown procedures, social isolation, and public fear. The use of technology such as social media has increased with research highlighting the harm of overuse. The purpose of the current study is to investigate the psychometric properties of an Arabic translated version of the Bergen Social Media Addiction Scale (BSMAS) to assess for addictive social media use. Secondly, the study further examines the association between depression, social media addiction, and an individual’s sense of control. Specifically, the potential mediational role of …


Monitoring Quality Of Care In Hepatocellular Carcinoma: A Modified Delphi Consensus, Ashika D. Maharaj, John Lubel, Eileen Lam, Paul J. Clark, Oliver Duncan, Jacob George, Gary P. Jeffrey, Lara Lipton, Howard Liu, Geoffrey Mccaughan, Eu-Ling Neo, Jennifer Philip, Simone I. Strasser, Katherine Stuart, Alexander Thompson, Jonathan Tibballs, Thomas Tu, Michael C. Wallace, Alan Wigg, Marnie Wood, Amany Zekry, Elysia Greenhill, Liane J. Ioannou, Golo Ahlenstiel, Kaye Bowers, Stephen J. Clarke, Anouk Dev, Michael Fink, Mark Goodwin, Christos S. Karapetis, Miriam T. Levy, Kate Muller, James O'Beirne, David Pryor, James Seow, Nicholas Shackel, Caroline Tallis, Nick Butler, John K. Olynyk, Kate Reed-Cox, John R. Zalcberg, Stuart K. Roberts Nov 2022

Monitoring Quality Of Care In Hepatocellular Carcinoma: A Modified Delphi Consensus, Ashika D. Maharaj, John Lubel, Eileen Lam, Paul J. Clark, Oliver Duncan, Jacob George, Gary P. Jeffrey, Lara Lipton, Howard Liu, Geoffrey Mccaughan, Eu-Ling Neo, Jennifer Philip, Simone I. Strasser, Katherine Stuart, Alexander Thompson, Jonathan Tibballs, Thomas Tu, Michael C. Wallace, Alan Wigg, Marnie Wood, Amany Zekry, Elysia Greenhill, Liane J. Ioannou, Golo Ahlenstiel, Kaye Bowers, Stephen J. Clarke, Anouk Dev, Michael Fink, Mark Goodwin, Christos S. Karapetis, Miriam T. Levy, Kate Muller, James O'Beirne, David Pryor, James Seow, Nicholas Shackel, Caroline Tallis, Nick Butler, John K. Olynyk, Kate Reed-Cox, John R. Zalcberg, Stuart K. Roberts

Research outputs 2022 to 2026

Although there are several established international guidelines on the management of hepatocellular carcinoma (HCC), there is limited information detailing specific indicators of good quality care. The aim of this study was to develop a core set of quality indicators (QIs) to underpin the management of HCC. We undertook a modified, two-round, Delphi consensus study comprising a working group and experts involved in the management of HCC as well as consumer representatives. QIs were derived from an extensive review of the literature. The role of the participants was to identify the most important and measurable QIs for inclusion in an HCC …