Digital Commons Network^™

Open-Source Benchmarking Of Ibd Segment Detection Methods For Biobank-Scale Cohorts, Kecong Tang, Ardalan Naseri, Yuan Wei, Shaojie Zhang, Degui Zhi

Faculty, Staff and Student Publications

In the recent biobank era of genetics, the problem of identical-by-descent (IBD) segment detection received renewed interest, as IBD segments in large cohorts offer unprecedented opportunities in the study of population and genealogical history, as well as genetic association of long haplotypes. While a new generation of efficient methods for IBD segment detection becomes available, direct comparison of these methods is difficult: existing benchmarks were often evaluated in different datasets, with some not openly accessible; methods benchmarked were run under suboptimal parameters; and benchmark performance metrics were not defined consistently. Here, we developed a comprehensive and completely open-source evaluation of …

A Uab Love Story: Engaged History Majors Set To Graduate Together Dec. 10, Micah Hardge

Browse All News

No abstract provided.

Return, Leilani Bascom

Theses and Dissertations

Return is a video-based installation which includes sound, performance, and textile elements. Leilani Bascom is the lone actor navigating the water and where the water meets the land in this personal project exploring concepts of the life cycle from birth to death and rebirth. Life's paradox of struggle and release unfolds with imagery of battling through waves to swim deep underwater, fighting a river current and then surrendering to the flow, and carving a hole in the sand to climb into and be held. Viewers are immersed in the movement and sounds of water to witness the power and meaning …

Audience And Mockingbird: A Narrator's Guide, Charisse Baxter

Theses and Dissertations

While adaptation research possesses longstanding applications and ample material for study, seldom has a data set proven to be as iconic and culturally relevant as the various iterations of To Kill a Mockingbird. Novel to film to stage play, and then nearly 60 years later to a second stage play, the story has resonated with audiences in a range of performative variations. A defining characteristic of Harper Lee's tale is her use of a narrator; this characteristic provides an effective entry-point in examining the two stage adaptations by way of their interpretation of the narrator. A study of the respective …

Exhibit: Documenting The Presence Of Hispanic And Latinx Students At The University Of Kentucky, Ruth E. Bryan, Taylor Leigh

Library Presentations

From December 6-7, 2022, at the request of Hispanic Studies Department faculty Heather Campbell-Speltz, University Archivist Ruth Bryan and Hispanic Studies Librarian Taylor Leigh presented to students in classes SPA 211 and 208 an exhibit of items from the University Archives in the UK Libraries Special Collections Research Center that document the presence of Hispanic and Latinx students at the University of Kentucky. Starting with the first student from Latin America to graduate from the Agricultural and Mechanical College in 1878 (the precursor to today’s university) and going through some of the activities of the Latino Student Union in 2022, …

Agenda Setting And Europe's Common Immigration Policy, Jamie P. Surface

Dissertations and Theses

For over a decade the European Union has been immersed in an immigration crisis. As the desired destination for millions of people fleeing unrest in the Middle East and war in Ukraine, the EU has developed its own social, political, and humanitarian crisis. Lacking policy commonality across its member states on how to accept and manage the mass waves of migrants, the EU continues to struggle with implementing a common immigration policy. This research examines EU immigration issues, policies, and the failures of successful collaboration stymying the implementation of a standard immigration policy. Using the agenda setting model of John …

Possibilities For Inertial Electrostatic Confinement Fusion, Jeffrey Edward Black

Dissertations and Theses

While most of the fusion energy research is focused on magnetic confinement, there have been several alternative confinement methods aimed at the development of smaller and less expensive reactors. A number of these devices utilize a spherically convergent beam of recirculating ions, a technique known as inertial electrostatic confinement (IEC). This study looks at several aspects of IEC devices, including measurements of the fusion rate of an IEC device with a wire mesh electrode cathode, and a solid titanium cathode. In addition, several computational studies were performed to explore the possibilities for IEC fusion. These include development of a 1D-1P …

Jan Kaulins, Oral History Interview, 2022, Laura Waskiewicz, Matt Jones

Oral Histories

In the Fall of 2022, Matt Jones’s Oral History Techniques class conducted a set of interviews documenting the stories behind the student unrest on Eastern Michigan University’s campus from 1966-1972. Jan Kaulins was the supreme justice on the student court at EMU during the late 1960s and early 1970s. Jan was involved with the student unrest on campus, and ruled on important cases that were brought to the court, such as the Second Coming trials. He went on to graduate school at the University of Michigan after EMU.

Using Extreme Pedagogy Toenhance Entrepreneurship Education, Dave Silberman, Herman Aguinis, Rob E. Carpenter

Human Resource Development Faculty Publications and Presentations

We address the ongoing concern that entrepreneurship education (EE) is not preparing students sufficiently well for jobs in the 21^st-century. We argue that many criticisms leveled against EE for not effectively addressing the entrepreneurial skills gap are due in part to EE’s emphasis on the roles of specific stakeholder groups separately (i.e., universities and their leaders, instructors, students, potential employers) rather than a shared focus on developing valuable graduates. Stated differently, there are competing and conflicting “ownerships” over the entrepreneurial skills gap. We enhance current pedagogical methods by offering a learning innovation called extreme pedagogy. Extreme pedagogy takes …

Factors Which Facilitate The Successful Inclusion Of Students With Learning Disabilities And Emotional And Behavioral Disabilities, Mackenzie Gabrielle Nadeau

Senior Honors Theses

This paper examines the different types of strategies, supports, and technologies available to students who are classified with a learning disability (LD) or emotional and behavioral disability (EBD) in an inclusive setting. As the number of students with LD and EBD in a general, inclusive classroom setting is rising, it is necessary to find ways to maximize their educational performance. In an inclusive setting, children with disabilities receive instruction with support and accommodations alongside their non-disabled peers in their neighborhood school. The practice of inclusion promotes social interaction and peer-acceptance among students with and without disabilities, therefore providing opportunities for …

A Case Study Of A Low-Income African American Career Academy’S Approach To Student Services, Victor Hernandez-Gantes, Edward C. Fletcher Jr.

Journal of Research in Technical Careers

The provision of support services has been found critical for meeting the needs of students and their families, but related research in predominantly low-income, African American/Black communities, is limited. Thus, through a case study we explored how a school, located in a low-income area with a predominantly African American/Black population, adopted and enacted support services. The setting was an urban high school with an enrollment of 700 students who are predominantly African American (98%) and 100% low-income. We conducted interviews with district, school, and community stakeholders; and we followed a thematic approach for the analysis. A major finding was that …

"A New Side Of One And The Same Lord": Helmut Thielicke's Theological Anthropology As An Evangelical Response To Contemporary Humanity's Existential Anfechtung, Mark H. Lack

Witness

No abstract provided.

Missional Praise: Overflowing Worship In Times Of Revival, Richard Mclaughlin

Witness

No abstract provided.

Redbird Buzz Episode 15: Dr. Mary Manz Simon '69, December 6, 2022, Rachel Kobus, Mary Manz Simon

Redbird Buzz (2022-2025)

Author and educational consultant Dr. Mary Manz Simon ’69 joins Redbird Buzz to share her unique path from kindergarten teacher to children’s author and educational consultant for companies like Crayola, DreamWorks, Sony, and more. Simon shares what is truly important when it comes to passion, shaping the lives of children as educators, and how learning each day ourselves makes us a better person. She also gives a brief insight into her friendship with beloved television host Mr. Fred Rogers.

Payton's Final Master's Portfolio, Payton Boshears

Master of Arts in English Plan II Graduate Projects

Here is my final Master's Portfolio. I did not have specialization for the English program, so for the portfolio I chose four different projects that represent the variety of courses I have taken during my time here at BGSU.

Career And Technical Education Teachers’ Perceptions Of Their Profession And Willingness To Encourage Students To Enter A Cte Teaching Career, Michael F. Kosloski, Philip A. Reed, Roberto Loya, Mariam Abdelhamid

Journal of Research in Technical Careers

This study examined the current climate of how Virginia CTE teachers perceive their profession and if they are encouraging their students to enter the teaching profession. A survey developed by the National Center for Education Statistics was submitted to CTE teachers in Virginia (n = 743) to address these questions. Descriptive statistics helped to determine that CTE teachers are generally satisfied with their careers but dissatisfied with factors over which they have no control, and the number of teachers recommending the profession to their students in recent years has decreased considerably. A Pareto analysis was conducted, and the results …

Students Top Regional Ethics Competition, Eye National Title, Clara Turnage

University of Mississippi News

Ethics Bowl competitors sharpen research, ethical knowledge, communication skills

Living With Urban Foxes, John Hadidian

WellBeing News

The red fox (Vulpes vulpes) is the most widely distributed wild carnivore on the planet, with a natural range that spans the entire Northern Hemisphere. Below the equator, foxes have been introduced to the Falkland Islands and Australia, where they cause widespread damage to domestic livestock and native fauna. Fox predation is a common cause of fox-human conflict throughout their range, leading to a complex relationship with humanity. This relationship varies where the fox is alternatively regarded as verminous, if not demonic, but is also an object of affection and regard — a typically bipolar human-animal relationship.[i]

Combating Social Isolation And Loneliness Among Veterans After Separation From Military Service, Emily Graham

Population Health Research Brief Series

Half of U.S. veterans report feeling like they don’t belong in society after separation from military service. Lack of belonging is often associated with feeling socially isolated or lonely. These feelings may increase the risk of veterans experiencing poor mental and physical health outcomes. This brief explores the negative impacts of social isolation and loneliness on veteran health and wellbeing. It calls for expanded veterans programing that connects veterans to each other while mimicking the values veterans miss about military life, including camaraderie, identity, purpose, physical activity, and learning.

Professor Launches Lgbtqia+ Emergency Fund, Benita Whitehorn

University of Mississippi News

Sarah Isom Center director organized nonprofit to address concern

Unfavorable Social Determinants Of Health Are Associated With Higher Burden Of Financial Toxicity Among Patients With Atherosclerotic Cardiovascular Disease In The Us: Findings From The National Health Interview Survey, Javier Valero-Elizondo, Zulqarnain Javed, Rohan Khera, Mauricio E Tano, Ramzi Dudum, Isaac Acquah, Adnan A Hyder, Julia Andrieni, Garima Sharma, Michael J Blaha, Salim S Virani, Ron Blankstein, Miguel Cainzos-Achirica, Khurram Nasir

Faculty, Staff and Students Publications

• D: PMC9727868

Tele-Medicine Based And Self-Administered Interactive Exercise Program (Tele-Exergame) To Improve Cognition In Older Adults With Mild Cognitive Impairment Or Dementia: A Feasibility, Acceptability, And Proof-Of-Concept Study, Catherine Park, Ram Kinker Mishra, Michele K York, Ana Enriquez, Abigail Lindsay, Gregory Barchard, Ashkan Vaziri, Bijan Najafi

Center on Aging Staff Publications

Improved life expectancy is increasing the number of older adults who suffer from motor-cognitive decline. Unfortunately, conventional balance exercise programs are not tailored to patients with cognitive impairments, and exercise adherence is often poor due to unsupervised settings. This study describes the acceptability and feasibility of a sensor-based in-home interactive exercise system, called tele-Exergame, used by older adults with mild cognitive impairment (MCI) or dementia. Our tele-Exergame is specifically designed to improve balance and cognition during distractive conditioning while a telemedicine interface remotely supervises the exercise, and its exercises are gamified balance tasks with explicit augmented visual feedback. Fourteen adults …

Ypfs Lessons Learned Oral History Project: An Interview With Vincenzo La Via, Vincenzo La Via, Mercedes Cardona

Documents

No abstract provided.

Ypfs Lessons Learned Oral History Project: An Interview With Stefan Ingves, Stefan Ingves, Maryann Haggerty, Carey Mott

Documents

No abstract provided.

The Double Silence: Reflections On Music And Musicians, Antoni Pizà

Publications and Research

A translation of EL DOBLE SILENCI, published in Catalan in 2003. The book is a compilation of essays originally published in Diario de Mallorca (2000-2003).

Does Central Executive Training And/Or Inhibitory Control Training Improve Emotion Regulation For Children With Attention-Deficit/Hyperactivity Disorder? A Randomized Controlled Trial, Nicole B. Groves, Elizabeth S.M. Chan, Carolyn L. Marsh, Fatou Gaye, Emma M. Jaisle, Michael J. Kofler

Department of Psychology Faculty Scholarship and Creative Works

Introduction: Approximately 48–54% of children with attention-deficit/hyperactivity disorder (ADHD) have impairing difficulties with emotion regulation, and these difficulties are not ameliorated by first-line ADHD treatments. Working memory and inhibitory control represent promising intervention targets given their functional, if not causal, links with ADHD-related emotion dysregulation. Methods: This preregistered randomized controlled trial tested whether two digital therapeutic training protocols that have been previously shown to improve working memory (Central Executive Training [CET]) and inhibitory control (Inhibitory Control Training [ICT]) can improve emotion regulation in a sample of 94 children with ADHD aged 8–13 years (M = 10.22, SD = 1.43; 76% …

High Resolution Modeling Of Vegetation Reveals Large Summertime Biogenic Co2 Fluxes In New York City, Dandan Wei, Andrew Reinmann, Luke D. Schiferl, Roisin Commane

Advanced Science Research Center

Cities are beginning to monitor atmospheric carbon dioxide (CO₂) to assess the efficacy of their climate policies. However, changes in anthropogenic CO₂ emissions must be separated from biospheric CO₂ fluxes which have a large seasonal cycle. Urban vegetation (e.g. lawns, trees along street and in parks, etc) in developed land covers is often omitted in regional biogenic CO₂ flux models. We set up a biosphere model to estimate the regional biogenic CO₂ fluxes in New York City (NYC) and assess the importance of vegetation within developed land covers. The model incorporates a high-resolution (30 …

Palliative Care Reduces Emergency Room Visits And Total Hospital Days Among Patients With Metastatic Hpb And Gi Cancers, Angelle A. Billiot, Denise M. Danos, Jenny Stevens, Katie M. Vance, Mary C. Raven, John M. Lyons

School of Public Health Faculty Publications

Palliative care services (PCS) have improved quality of life for patients across various cancer subtypes. Minimal data exists regarding PCSfor metastatic hepatopancreaticobiliary (HPB) and gastrointestinal (GI) cancers. We assessed the impact of PCS on emergency department visits, hospital admissions, and survival among these patients. Patients with metastatic HPB and GI cancer referred to outpatient PCS between 2014 and 2018 at a single institution were included. We compared the demographics, outcomes, and end-of-life indicators between those who did and did not receive PCS. The study included 183 patients, with 118 (64.5%) having received PCS. There were no significant differences in age, …

Ucc Minutes 12-6-22, Angela Brock

UCC Agendas/Minutes

No abstract provided.

In Silico Identification Of A Β2-Adrenoceptor Allosteric Site That Selectively Augments Canonical Β2ar-Gs Signaling And Function, Sushrut D Shah, Christoffer Lind, Francesco De Pascali, Raymond B Penn, Alexander D Mackerell, Deepak A Deshpande

Department of Biochemistry and Molecular Biology Faculty Papers

Activation of β2-adrenoceptors (β2ARs) causes airway smooth muscle (ASM) relaxation and bronchodilation, and β2AR agonists (β-agonists) are front-line treatments for asthma and other obstructive lung diseases. However, the therapeutic efficacy of β-agonists is limited by agonist-induced β2AR desensitization and noncanonical β2AR signaling involving β-arrestin that is shown to promote asthma pathophysiology. Accordingly, we undertook the identification of an allosteric site on β2AR that could modulate the activity of β-agonists to overcome these limitations. We employed the site identification by ligand competitive saturation (SILCS) computational method to comprehensively map the entire 3D structure of in silico-generated β2AR intermediate conformations and identified …