Digital Commons Network^™

Neurobiological Pathways Underlying Brain Tumor Progression: Basis For Oncogenicity And Opportunities For Immunotherapeutic Intervention, Carrie E. Andrews, Jenny Zilberberg, Raul Perez-Olle, David Andrews, Mark A. Exley

Department of Neurosurgery Faculty Papers

Both primary and metastatic brain tumors rely on signals from the surrounding environment for their survival and progression. In particular, the most common and lethal brain cancer, glioblastoma (GBM), derived from glial cells (astrocytes or microglia), has been shown to integrate into synaptic networks and to receive paracrine signals from neighbouring tumor microenvironment (TME) cells. There is increasing evidence that metastatic disease in the brain exhibits similar behavior. The TME both maintains malignant cells and is maintained by them, a process that relies on cancer stem cells (CSCs). These stem cells and their signaling mechanisms, including in the case of …

Immunotherapy Of Tsa-1.C4 Or In Combination With Bnz Confers Protection Against Trypanosoma Cruzi Infection With A Distinct Cytokine Response, Landy Magaly Pech-Pisté, Victor Dzul-Huchim, Christian Florian Teh-Poot, Fabian Gusovsky, Kathryn Jones, Peter Hotez, Liliana Estefanía Villanueva-Lizama, Maria Elena Bottazzi, Jaime Ortega-Lopez, Julio Vladimir Cruz-Chan

Faculty, Staff and Students Publications

Chagas disease is a poverty-related neglected tropical disease caused by the protozoan Trypanosoma cruzi affecting approximately 6.3 million people, predominantly in the Americas. Approximately 30% of T. cruzi infections progress to chronic cardiomyopathy and 10% of these cases end in death from cardiac failure. The first-line drug Benznidazole (BNZ) require a prolonged treatment regimen and can be highly toxic. Here, we evaluate a therapeutic vaccine in T. cruzi-infected mice, based on the recombinant Trypomastigote Surface Antigen 1 (TSA-1.C4) protein and the emulsified adjuvant E6020, and in combination with a suboptimal dose of BNZ. We observed a reduced burden parasite in …

Self-Clustering Of Three Cbx2 Molecules Drives Prc2 To Promote Facultative Heterochromatinization Of Polycomb Target Genes, Steven Ingersoll, Abby Trouth, J Carlos Angel, Xinlong Luo, Axel Espinoza, Joey Wen, Chengjie Zhu, Joseph Tucker, Kalkidan Astatike, Christopher J Phiel, Hatim Sabaawy, Tatiana G Kutateladze, Tao P Wu, Tingting Yao, Chao Lu, Srinivas Ramachandran, Xiaojun Ren

Faculty, Staff and Students Publications

Phase separation is increasingly recognized in facultative heterochromatinization of Polycomb target genes; however, the mechanisms underlying this process remain obscure. Using single-molecule imaging and tracking, we show that individual condensates in mouse embryonic stem cells (mESCs) contain approximately 3 CBX2 molecules and numerous Polycomb repressive complex (PRC)1 and PRC2 subunits and indicate that the composition and dynamics of condensates are developmentally regulated. We reveal that CBX2 clusters PRC2 and controls the spatial distribution of both PRC2 and H3K27me3. Using genomic approaches, we demonstrate that CBX2 binds to condensate initiation sites, which are enriched for PRC2 nucleation sites. CBX2 deletion causes …

Immunotherapy Of Tsa-1.C4 Or In Combination With Bnz Confers Protection Against Trypanosoma Cruzi Infection With A Distinct Cytokine Response, Landy Magaly Pech-Pisté, Victor Dzul-Huchim, Christian Florian Teh-Poot, Fabian Gusovsky, Kathryn Jones, Peter Hotez, Liliana Estefanía Villanueva-Lizama, Maria Elena Bottazzi, Jaime Ortega-Lopez, Julio Vladimir Cruz-Chan

Faculty, Staff and Students Publications

Chagas disease is a poverty-related neglected tropical disease caused by the protozoan Trypanosoma cruzi affecting approximately 6.3 million people, predominantly in the Americas. Approximately 30% of T. cruzi infections progress to chronic cardiomyopathy and 10% of these cases end in death from cardiac failure. The first-line drug Benznidazole (BNZ) require a prolonged treatment regimen and can be highly toxic. Here, we evaluate a therapeutic vaccine in T. cruzi-infected mice, based on the recombinant Trypomastigote Surface Antigen 1 (TSA-1.C4) protein and the emulsified adjuvant E6020, and in combination with a suboptimal dose of BNZ. We observed a reduced burden parasite in …

Graduate Student Supervision And Artificial Intelligence: Findings From Academic Faculty Interviews Across Disciplines, Kari D. Weaver, Nadine Fladd

Transforming Libraries for Graduate Students

There is widespread discussion in higher education about the potential implications of GenAI for research and writing tasks (George, 2023). Many graduate students are under intense pressure to finish their degree milestones in a timely manner, and these rapidly evolving technologies offer the potential to optimize and automate much of the research and writing process. But the ethical, developmental, and career implications of graduate students – both masters’ and doctoral – using these technologies requires particularly careful consideration, as these students are simultaneously learners, scholars, and, sometimes, educators. Although emerging research about GenAI use in higher education has examined the …

Teaching Evidence-Based Practice In Social Work: Practical Instructional Design Approaches For Graduate Students, Nicholas D. Bambach

Transforming Libraries for Graduate Students

Across the social and health sciences, evidence-based practice (EBP) serves as a cornerstone of professional education and links research-based knowledge to real-world decision-making. Students are expected to integrate empirical findings with client needs, ethical considerations, and professional best practices. Yet many graduate students struggle to translate theoretical concepts into applied practice. Academic librarians, particularly those serving as subject liaisons and specialists, are well positioned to partner with social work faculty to design scaffolded instructional experiences that integrate research literacy with social work’s ethical and humanistic frameworks. Through librarian–faculty partnerships, librarians can help students critically engage with research evidence while honoring …

Review Of Christian De Chergé: Spiritual Writings, William Skudlarek

The Journal of Social Encounters

No abstract provided.

Review Of Chosen Peoples: Christianity And Political Imagination In South Sudan, John Ashworth

The Journal of Social Encounters

No abstract provided.

Dating Among University Undergraduates Living With Disability In South-Western Nigeria, Usman A. Ojedokun, Bukunmi I. Oluborode, Lateef J. Adeyemo

The Journal of Social Encounters

In many university campuses in Nigeria, undergraduates living with disability are visible and functionally involved in academic, political, social, and religious activities. However, the social life of these students is hardly the focus of scholarly research. Therefore, this study explored dating behaviours among undergraduates of selected public universities in south-western Nigeria living with disability. The social disability model was employed as the conceptual framework. Data were elicited through in-depth interview and focus group discussion methods.  Findings showed that the choice of partners among undergraduates living with disability was guided by trust, communication, emotional safety, shared values, and acceptance of disability …

Review Essay: Welcoming Iranian Refugees And Immigrants To Toronto, Canada, Paul Pynkoski

The Journal of Social Encounters

No abstract provided.

Festival Diplomacy (Ceremony Diplomacy) As A Lesser-Known Form Of Cultural Diplomacy By Emerging Non-State Actors: The Newroz Legacy Of The Kurdish Regional Resistance In Iraq And Syria, Khaled Sheykholeslami

The Journal of Social Encounters

Kurds as the second largest ethnic groups in Iraq and Syria are the only nation in these two major-Arab countries that celebrate Newroz every year. However, as a minority community divided among different Middle Eastern countries, the arrival of the new year and the celebration of Newroz seem to have taken on a political significance beyond merely celebrating spring and the end of winter. This essay argues that Newroz has evolved from a cultural celebration into a strategic instrument of non-state cultural diplomacy used by Kurdish actors in Iraq and Syria to resist centralizing state power and project transnational identity. …

Geopolitical Transformation In The Post-October 7 Middle East (2023–2025): Power Shifts Vs. Structural Shifts, Nael Shama

The Journal of Social Encounters

This essay investigates the geopolitical shifts that unfolded in the Middle East from October 2023 to the end of 2025, stimulated by the surprise attack by Hamas on Israel on October 7, 2023, and the subsequent events it triggered. These included military confrontations between Israel and each of Hamas, Hezbollah and Iran, the fall of the Assad regime in Syria, and Houthi attacks in the Red Sea. The essay demonstrates that these developments have reshaped power positions and alliances in the Middle East, leading to a more complex and unpredictable geopolitical landscape. It sketches out the new regional balance of …

Countering Social Encounters: Darwish’S “Speech Of The Red Indian”, J. Kristen Urban

The Journal of Social Encounters

In June 2025 the Washington D.C. Arab Center held a conference at the National Press Club titled, “A Historic Juncture: Israel’s Destruction of Gaza and the Palestinian Future.”  The discussion sparked an incisive question: Would such a future follow a Palestinian-owned trajectory?  Incisive, because Palestinians have not owned their trajectory since the 1915 Sykes-Picot Agreement, have consistently been defined in negative terms, and have lived with the ambiguity of existing while remaining unrecognized.  Growing up within Israel, Palestine’s national poet, Mahmoud Darwish (1941-2008), experienced this paradox firsthand, and explored it directly in “Speech of the Red Indian,” a poem written …

Gender Justice Lessons From North-East Syria Amidst Patriarchal Perpetuation In The New Syrian Arab Republic?, Theresa Wagner

The Journal of Social Encounters

The overthrow of Bashar al-Assad, whose family had ruled Syria for over sixty years, and his government by Hai’at Tahrir asch-Scham (HTS) signified for many the beginning of a new era of democracy and freedom after thirteen years of civil war. People in the Democratic Autonomous Administration of North and East Syria (DAANES), a self-governing region that had not been ruled by the Syrian state since 2012, joined in with the celebrating crowds. However, they remained skeptical of HTS, which originated as a branch of al-Qaeda, known back then as Jabhat al-Nusra. Since taking on government responsibilities in the new …

Introduction: The Arab World And Middle East In An Age Of Dynamism And Change, Eslam Elbahlawan, Mawa Mohamed, Ron Pagnucco

The Journal of Social Encounters

On February 28, 2026, the United States and Israel began a massive joint military attack against the Islamic Republic of Iran to which Iran has responded. At the time of the publication of this issue, the fighting continues and could become more widespread; the ultimate outcome of the conflict is unknown.  This conflict highlights the importance of a deeper understanding of the region.

In the shadow of these events, people of the Middle East once again find their lives reordered by decisions taken far above their heads and far beyond their borders. The current war not only devastates cities, infrastructure, …

The Musicale Newspaper: Volume 3, Number 9

Arthur Saft Family Papers

Volume 3, Number 3 of The Musicale Newspaper on December of 1917. Helen Saft is mentioned in one of the newspaper reports.

Girls' Preferences For Coaches' Supportive Behaviors, Efrat Abadi

Journal of Athlete Development and Experience

Participation of girls in sports is associated with positive outcomes; however, girls continue to face barriers to participation due to gender, age, and cultural factors. Coaches play a pivotal role in girls' persistence in sports, with influential mechanisms including providing social support and cultivating high-quality coach-athlete relationships. Nevertheless, limited research has explored girls' specific preferences regarding coaches' supportive behaviors, particularly within diverse cultural contexts. Much of the existing literature is based on data from Western countries, with findings often generalized across cultural settings - without considering girls from Mediterranean populations, who remain underrepresented in research. This study employed a qualitative …

What’S Critical In Critical Media Literacy? Barriers And Good Practices In Adult Education, Stefanie Mayer, Stefanie Fridrik, Josef Mühlbauer, Brigitte Temel, Viktoria Eberhardt

Journal of Media Literacy Education Pre-Prints

While there is broad consensus regarding the social and educational need for CML, its actual didactic content and especially the meaning of ‘critical’ are far from clear. The article argues for a turn to educational practices. Findings are based on empirical research on adult education in Vienna (Austria) consisting mainly of interviews with expert-practitioners in the field of adult education and media and/or digital literacy. We confront academic definitions of the critical impetus of CML with an analysis of innovative projects, which were designed for accessibility and addressed learners facing high educational barriers. Our findings encourage a turn towards the …

Transitioning From The Consolidated Framework For Implementation Research (Cfir) To The Updated Cfir For Quantitative Measurement Of Influences On Implementation Outcomes In A Faith-Based Walking Intervention, Ruth P. Saunders, Sarah Wilcox Phd, A. Caroline Rudisill, Andrew T. Kaczynski, Jasmin Parker-Brown

Faculty Publications

Background Our research team has used the highly cited Consolidated Framework for Implementation Research (CFIR) a priori throughout the research process to better understand influences on implementation outcomes of an organizational change innovation to promote physical activity and healthy eating in faith-based settings. CFIR has recently been updated to include substantial changes in some domains and constructs, and our research team is preparing to carry out a new implementation study of an evidence-based innovation in churches. The purpose of this paper is to describe the process we undertook to map CFIR domains, constructs, and quantitative measures from our earlier studies …

Department Chair: Perceived Training Needs, Holly M. Clifford

Morehead State Theses and Dissertations

A capstone submitted in partial fulfillment of the requirements for the degree of Doctor of Education in the Ernst and Sara Lane Volgenau College of Education at Morehead State University by Holly M. Clifford on March 18, 2026.

Spectrum, Volume 56, Issue 6, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include:  Honorees with Heart: The Pioneer Scholarship Gala -- US - Iran Conflict -- Classrooms Over Seas -- SHU Springs Back To Life -- Singing to the Mountains -- Program History Sends Pioneers to the Championship -- History on the Mat

Cuny Academic Works: What It Is And Why You Should Submit Your Works, Jojo Karlin

Publications and Research

CUNY Academic Works was launched in 2014 to serve the faculty, staff, and students of CUNY. The root of this open access institutional repository was a response to the Budapest Open Access Initiative of 2002, which led to a CUNY University Faculty Senate Resolution in 2011. These slides were used in a presentation given at Lehman College and were developed from a presentation given at La Guardia Community College.

Cover And Contents

Turkish Journal of Zoology

No abstract provided.

Nonnative Crayfish In Türkiye: Presence Records, Invasion Pathways, And Ecological Risks, Muzaffer Mustafa Harlioğlu

Turkish Journal of Zoology

The globalization of trade, aquaculture, and the ornamental pet industry has accelerated the transboundary movement of nonnative crayfish species, with significant ecological consequences. Türkiye, a biodiversity-rich country bridging Europe and Asia, has increasingly become a point of concern due to the rising presence of alien crayfish taxa introduced primarily via the aquarium trade and scientific research. This study investigates the presence records of nonnative crayfish species in Türkiye, identifies their likely introduction pathways, and outlines potential future outspread routes across the major freshwater basins of the country. Species such as Procambarus clarkii, Cherax quadricarinatus, C. albertisii, and Cambarellus patzcuarensis have …

Morphometric And Reproductive Divergence Of Deep-Water Shrimps Plesionika Martia (A. Milne-Edwards, 1883) And P. Heterocarpus (A. Costa, 1871) Along A Depth Gradient In The Eastern Aegean Sea, Murat Özbek, Cengi̇z Koçak, Zafer Tosunoğlu

Turkish Journal of Zoology

This study provides a comparative analysis of two deep-water pandalid shrimp  species, Plesionika martia and P. heterocarpus, based on monthly samples collected  over one year in the Eastern Aegean Sea. Specimens were obtained from species-specific depth zones (550 m for P. martia and 350 m for P. heterocarpus) to examine  morphometric traits, sexual dimorphism, and reproductive patterns. A total of 4419  individuals were analyzed. Females were significantly larger and more abundant than  males (K–S test, p < 0.05), indicating pronounced sexual dimorphism. Length–weight relationships revealed negative allometric growth in both species, confirmed  by t-tests (p < 0.05). Reproductive activity differed markedly: P. martia showed a short  and distinct spawning period peaking in late autumn, whereas P. heterocarpus  displayed a prolonged, bimodal cycle with peaks in spring and summer. The gonadosomatic index (GSI) and the proportion of ovigerous females varied  significantly by season and species. A strong positive correlation between carapace  length and gonad weight was found, with a more linear relationship in P. martia and  greater variability in P. heterocarpus. Size at first maturity (L₅₀) was estimated at 22.3  mm CL for P. heterocarpus but could not be reliably determined for P. martia  due to limited small size data, likely reflecting ontogenetic depth segregation. The  consistent bathymetric separation between these species—also reported in the  Western Mediterranean—suggests ecological niche differentiation. Species-specific  management measures, including depth-based fishing restrictions and temporal  closures during reproductive peaks, are recommended to support the sustainable  exploitation of deep sea shrimp stocks in the region.

Species Identification Using Otolith Morphometry Of Four Gurnards (Family: Triglidae) From  Edremit Bay (Aegean Sea), Ahmet Mert Şenbahar, Di̇lek İlhan, Aydin Ünlüoğlu, Sencer Akalin

Turkish Journal of Zoology

Shape and size analyses of otoliths are widely considered appropriate tools for distinguishing between fish species and for assessing populations and stocks.  The present study aims to distinguish four gurnard species collected from Edremit  Bay (Aegean Sea) based on variations in their otolith shape morphology. A total of 60  specimens of Eutrigla gurnardus, 64 of Chelidonichthys lastoviza, 60 of  Chelidonichthys lucerna, and 60 of Lepidotrigla cavillone were analyzed. No  significant intraspecific differences were noted in the morphology of the left and right  otoliths, and so only the left sagittal otoliths were subjected to further analysis. Otolith  shape was quantified using …

Identifying Common Trend Determinants In Panel Data, Yoonseok Lee, Peter C. Phillips, Suyong Song, Donggyu Sul

Center for Policy Research

This paper develops a novel method for identifying observable determinants of latent common trends in nonstationary panel data, which are typically removed or controlled in two-way fixed effects regressions. By examining cross sectional dispersion processes, we assess whether panel series exhibit distributional convergence toward specific observed time series, revealing them as long run determinants of the underlying latent trend. The approach also offers a new perspective on cointegration between time series and panel data, focusing on the relative variation of the panel data with respect to the cointegration error. Applying this method to U.S. state-level crime rates demonstrates that the …

Depression And Psychotic Disorders Worsen Perioperative Outcomes And Increase Resource Utilization After Multilevel Lumbar Fusion: Implications For Screening And Perioperative Care, Leonidas E. Mastrokostas, Paul G. Mastrokostas, Luke B. Schwartz, Abigail Razi, Sean Inzerillo, John K. Houten, Arya Varthi, Alex R. Vaccaro, Jad Bou Monsef, Afshin E. Razi, Mitchell K. Ng

Rothman Institute Papers

CONTEXT: Multilevel lumbar fusion use has increased with an aging U.S. population. Depression and psychotic disorders are linked to poorer surgical outcomes, but their effects in this setting are unclear.

AIMS: The aims of this study were to quantify the prevalence of these disorders and evaluate associations with perioperative outcomes and resource use.

SETTINGS AND DESIGN: This was a retrospective cohort study using the National Inpatient Sample from 2016 to 2022.

SUBJECTS AND METHODS: Depression and psychotic disorders were defined using Elixhauser-derived indicators. Outcomes included medical and mechanical complications, discharge disposition, length of stay (LOS), and costs.

STATISTICAL ANALYSIS USED: …

Examining The Association Between Awareness Of Soil Ecosystem Services And Yard Management In A Highly Urbanized And Tropical Watershed, Luis Kidany Selles, Elvia J. Melendez_Ackerman

Cities and the Environment (CATE)

Residential soil should be viewed as vital elements for sustainable cities. Of concern is that residents can be managing residential green spaces without a clear understanding of soil benefits. We performed 275 surveys in the Rio Piedras Watershed, Puerto Rico to evaluate: (1) the level of residents’ awareness about the contribution of soils to ecosystem services, and (2) the association between yard management practices with household socioeconomics and the level of residents’ awareness regarding residential soil ecosystem services. Results showed that residents were significantly less aware of the importance of soil ecosystem services in their yards compared to that of …

The Anthropology Of Life: An Interview With Perig Pitrou, Perig Pitrou, Tomas De Oliveira, Maddalena Canna

Transatlantic Forum

This interview focuses on the proposal for an "anthropology of life" developed by Perig Pitrou. The conversation traces the origins of this framework to fieldwork with the Mixe of Mexico, where rituals involving the metaperson "He Who Makes Being Alive" revealed a crucial distinction between "the living" (living beings) and "life" (the causes that make them alive). This separation underpins a comparative model examining how societies socialize two fundamental dimensions: the power to generate life and the fragility of individual existences. Methodologically, the approach draws on the anthropology of techniques, employing the concept of "agentive configurations" to analyze how humans …