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A Thesis, Or Digressions On Sculptural Practice: In Which, Concepts & Influences Thereof Are Explained, Set Forth, Catalogued, Or Divulged By Way Of Commentaries To A Poem, First Conceived By The Artist, Fed Through Chatg.P.T., And Re-Edited By The Artist, To Which Are Added, Annotated References, Impressions And Ruminations Thereof, Also Including Private Thoughts & Personal Accounts Of The Artist, Jaimie An

Masters Theses

This thesis is an exercise in, perhaps a futile, attempt to trace just some of the ideas, stories, and musings I might meander through in my process. It’s not quite a map, nor is it a neat catalogue; it is a haphazard collection of tickets and receipts from a travel abroad, carelessly tossed in a carry-on, only to be stashed upon returning home. These ideas are derived from much greater thinkers and authors than myself; I am a mere collector or a translator, if that, and not a very good one, for much is lost. I do not claim comprehensive …

Winter Solstice, Jingwen Cao

Masters Theses

For a long time, I have been thinking about what contemporary photography is, what its position is, and what the relationship is between artists and audiences. At the same time, I was developing my concepts and photographic directions and trying to make my work and my perspective on photography relevant. Winter Solstice includes a series of essays that locate my thinking and my work. Its title references the longest night of the year.

The position of photography has changed significantly over the past few decades. The way people read photos is also changing. Perhaps because of reverence for art and …

Dreampool, Xia Li

Masters Theses

DREAMPOOL is a spatial experience of virtual architecture based on the public bathhouses of northern China during the 00s - 10s. It focuses on the significance of nostalgia and the connection between architectural space and the spiritual world. The dreampool began with my interest in Bathhouse and Dreamcore videos that were popularized on the Chinese internet during the pandemic.

Like every nostalgia trend emerging, such as steampunk, some young Chinese people are starting to miss their childhood life around the year 2000 at a time when they are losing their public space and socialization. Public bathhouses, as a collective memory …

Narrative Structures, Theodore Badenhausen

Masters Theses

This thesis explores the intersection of architecture, tradition, and environmental stewardship through a personal and analytical lens. The narrative begins with a reflection on coastal landscapes, revealing the transformative impact of natural forces and human intervention on the built environment. This evolving scenery serves as a metaphor for the broader discourse on the impermanence of architectural structures and their relationship with nature. The discussion transitions to the historical reliance on natural materials like stone, earth, and timber, which were overshadowed by the advent of concrete and steel. While these modern materials have dominated contemporary architecture, they pose environmental challenges and …

I Am Becoming., Dai Asano

Masters Theses

This is a collection of essays documenting my grappling with the idea that time is always in motion. When you say now, it is not now anymore, but we are still in now, a new now. How can I stay in the now without being swept away by the current of time? Describing a film by Ozu Yasujiro, Deleuze writes, “The vase in Late Spring is interposed between the daughter’s half smile and the beginning of her tears. There is becoming, change, passage. But the form of what changes does not itself change does not pass on. This is time, …

Trans-Species Communication, Fueled By Efforts Of Remediation, Naomi Canino

Masters Theses

Using science fiction pop culture and films as a basis to reposition the way that we think about communicating with plants as if they are sentient beings capable of human-like qualities, the process in which I intend to understand communication will be nestled in this fantastical, sci-fi realm of envisioning the world.

By analyzing existing forms of communication between humans, other living entities and themselves, I am challenging existing perspectives in order to propose new speculative processes of bio-based augmentation that can amplify a connection to plants. In order to pursue this exploration, I have chosen a real site in …

Corner Revolution: Beyond “Skynet”, Brightening Grey Space And Building Security, Caimin Shen

Masters Theses

The existence of surveillance areas restricts many bad behaviors, but why do we still feel vague anxiety and uneasiness when walking through street corners and promenades in a city protected by a network of cameras? As China has implemented grid management of cities through the establishment of the “Skynet”—— a system that uses facial recognition and surveillance cameras to strengthen public safety, the crime rate has dropped significantly. But public safety doesn’t just mean fewer criminal activities. Reducing people’s perceived insecurity and anxiety has become a new challenge in China today. “Corner Revolution” explores the transformative power of architectural design …

From One Nature To Another, Sarah Mann

Masters Theses

Lichen‭, ‬fungi‭, ‬and soil each represent a microcosm of nature‭. ‬They are all quintessential examples of complex symbiosis‭, ‬yet they are often treated as lifeless materials‭. ‬But what if we took a moment to connect with each one on a daily basis‭ - ‬would that impact the way we envision the future‭? ‬

For most of us‭, ‬our homes won’t be radically changing any time soon‭; ‬therefore‭, ‬From One Nature to‭ ‬Another‭ ‬invites us to bring these entities inside and‭ ‬reflect on their possibilities as collaborators‭. ‬Each piece was carefully researched and designed to‭ ‬provide the correct atmospheric …

Stand By, I'M Getting Ready., Mina Kim

Masters Theses

This thesis introduces a tangible user experience featuring wearable and portable items designed to allow anonymity while fostering social interaction. Covering one layer on one’s eyes and allowing for gradual removal, these items humorously transcend social norms, functioning as conduits for expressing inner emotions through an external action of signaling.

Inspired by the absence of physical-world boundaries akin to digital ‘Do Not Disturb’ modes, the research delves into crafting user experiences that safeguard personal boundaries in face-to-face interactions. It targets the apprehension felt in unfamiliar group settings and the impact of external stimuli on personal comfort. The research endeavors to …

Dimensional Dialogues, Farida Abousteit

Masters Theses

What does it mean to be, hear, interpret and understand language? And does it truly matter if we don't? This work explores linguistic translation and mistranslation, through the exploration of three-dimensional and interactive spaces that to create an opportunity to interact with language as an visual and felt environment; rather than language on a page or the spoken word.

When we stand next to typography, next to language, scaled up to a human-sized presence, do we find an immediate kinship and warmth towards it? Do we find ourselves more captivated and intrigued?

I believe that when we encounter the unfamiliar …

While We Were At Dinner, Anna Glass

Masters Theses

Mealtime is globally recognized as a time to gather, as food catalyzes connection. This project delves into this human practice of commensality and both explores and emphasizes the significance of communal eating and its benefits through designed objects. Through a collection of six designed dining experiments, this study examines the role of novel tabletop objects and unusually curated meal environments. The way these experiments are designed highlights how communal mealtime experiences can be used as tools for social engagement and disruptors of cultural norms.

Furniture and tableware designs have the power to challenge the assumed arrangement of traditional mealtime rituals, …

Man With Chest Pain, Fever, And Surprising Finding On Bedside Ultrasound, Omoyeni O Clement, Benjamin L Cooper

Faculty, Staff and Student Publications

No abstract provided.

Why Do Cochlear Implant Candidates Defer Surgery? A Retrospective Case-Control Study, Masanari G Kato, Vivian F Kaul, Diana Hallak, Lisa Zhang, Aaron C Moberly, Yin Ren

Faculty, Staff and Student Publications

Objective(s): Despite undergoing thorough cochlear implant (CI) candidacy evaluation and counseling, some patients ultimately elect against implantation. This study sought to identify patient-related and socioeconomic factors predicting CI deferral.

Methods: A retrospective study of adult (≥18 years old) CI candidates presenting between 2007 and 2021 at a tertiary academic CI center was performed. The primary outcome was device implantation. Data collected included age, gender, hearing status, race, zip code of residence, median family income (MFI), distance traveled from the CI center, marital status, employment status, and insurance status. Multivariable binary logistic regression was performed to identify predictors of implantation.

Results: …

Closure Of Dialysis Clinics In The United States In 2021-2023, Kamyar Kalantar-Zadeh, Dawn P Edwards, David Henner, Daniel L Landry, Donald A Molony, Preethi Yerram, On Behalf Of The Medical Advisory Council Of The National Forum Of Esrd Networks

Faculty, Staff and Student Publications

No abstract provided.

A Quantitative Analysis Of University Counselors And Student Affairs Personnel's Knowledge And Confidence In Working With Students With Autism Spectrum, Sandra Araiza Salazar

Dissertations

University counselors and student affairs personnel often find themselves unprepared to address the needs of undergraduate students with autism spectrum disorder. Many of these professionals are not receiving the proper training or education to prepare for the unique social, emotional, and academic needs of these neurodiverse students. Due to this trend, many university counselors and student affairs personnel may lack the necessary knowledge and confidence in serving this neurodiverse population. In this first-of-its-kind study, university counselors and student affairs personnel’s knowledge and confidence in working with undergraduate students with autism spectrum was analyzed. A nonrandom sample of university counselors and …

Mid- To Long-Term Outcomes In Patients After Hip Arthroscopy With Labral Reconstruction: A Systematic Review, David Nam-Woo Kim, Scott Fong, Nancy Park, Jacquelyn Simington, Louise Atadja, Nicholas Pettinelli, Michael S. Lee, Stephen M. Gillinov, David R. Maldonado, Andrew E. Jimenez

Student Publications

Background: There is a paucity of aggregate data documenting mid- to long-term outcomes of patients after hip arthroscopy with labral reconstruction.

Purpose: To report mid- to long-term outcomes in patients after undergoing either primary or revision hip arthroscopy with labral reconstruction for the treatment of irreparable labral tears.

Study design: Systematic review; Level of evidence, 4.

Methods: A systematic review of the PubMed, Cochrane, and Scopus databases in May 2022 was conducted with the following keywords: "hip arthroscopy,""labral reconstruction,""irreparable,""labrum,""reconstruction,""five-year,""midterm,""5 year,""long-term,""10 year," ten-year," and "femoroacetabular impingement" using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. Midterm was defined …

Variations In Trochlear Morphology Of Contemporary And Legacy Total Knee Arthroplasty Prostheses: A Review Of 22 Designs, Nikhil Gattu, Marriah Sutton, David B Doherty, Nicholas D Lanfermeijer, David Rodriguez-Quintana, Sabir K Ismaily, Camryn A Pletka, Philip C Noble, Shuyang Han

Faculty, Staff and Student Publications

Background: The morphology of the trochlear compartment of total knee arthroplasty (TKA) prostheses is a major determinant of postoperative patello-femoral kinematics, particularly with unresurfaced patellae. The objective of this study was to quantify and compare the trochlear morphology of a large series of contemporary and legacy TKA designs.

Methods: The 3-dimensional surface models of 22 femoral components (13 contemporary and 9 legacy) were created using high-resolution laser scanning. The trochlear profile of each component was analyzed from proximal to distal in 15° increments around the trochlear axis. In each profile, the following variables were measured: sulcus angle, medio-lateral deviation of …

Development Of An Antioxidant-Rich Sugar-Free Plantain Candy And Assessment Of Its Shelf Life In A Flexible Laminate, Poulami Sarkar, Paramita Bhattacharjee, Bidhan Das

Faculty, Staff and Student Publications

RESEARCH BACKGROUND: Candy is a popular confection worldwide, and it would be beneficial to society if it were converted into a source of antioxidant molecules to eliminate its adverse health effects. The amount of antioxidants available even in fruit candies is questionable due to the high thermal processing losses they undergo and the presence of various food additives. Plantains (

EXPERIMENTAL APPROACH: To accomplish the first objective, lyophilized plantain powder, sorbitol and mannitol were used as base materials with minimal additives under minimal processing conditions to reduce processing loss. Sensory, proximate, physicochemical and phytochemical properties, including the antioxidant synergy among …

Trends In Shortages Of Lead Chelators From 2001 To 2022, James D Whitledge, Pelayia Soto, Kieran M Glowacki, Diane P Calello, Erin R Fox, Maryann Mazer-Amirshahi

Faculty, Staff and Student Publications

OBJECTIVE: The study aims to describe drug shortages affecting lead chelators in the United States from 2001 through 2022.

METHODS: Drug shortage data were retrieved from the University of Utah Drug Information Service from January 1, 2001, through December 31, 2022. Shortages of first- and second-line lead chelators were analyzed. Drug class, formulation, administration route, shortage reason, shortage duration, generic status, single-source status, and presence of temporally overlapping shortages were examined. Total shortage months, percentages of study period on shortage, and median shortage durations were calculated.

RESULTS: Thirteen lead chelator shortages were reported during the study period. Median duration was …

Preventative Treatment Of Tuberous Sclerosis Complex With Sirolimus: Phase I Safety And Efficacy Results, Jamie K Capal, David M Ritter, David Neal Franz, Molly Griffith, Kristn Currans, Bridget Kent, E Martina Bebin, Hope Northrup, Mary Kay Koenig, Tomoyuki Mizuno, Alexander A Vinks, Stephanie L Galandi, Wujuan Zhang, Kenneth D R Setchell, Kelly M Kremer, Carlos M Prada, Hansel M Greiner, Katherine Holland-Bouley, Paul S Horn, Darcy A Krueger

Faculty, Staff and Student Publications

Objective: Tuberous sclerosis complex (TSC) results from overactivity of the mechanistic target of rapamycin (mTOR). Sirolimus and everolimus are mTOR inhibitors that treat most facets of TSC but are understudied in infants. We sought to understand the safety and potential efficacy of preventative sirolimus in infants with TSC.

Methods: We conducted a phase 1 clinical trial of sirolimus, treating five patients until 12 months of age. Enrolled infants had to be younger than 6 months of age with no history of seizures and no clinical indication for sirolimus treatment. Adverse events (AEs), tolerability, and blood concentrations of sirolimus measured by …

Pegvaliase For The Treatment Of Phenylketonuria: Final Results Of A Long-Term Phase 3 Clinical Trial Program, Cary O Harding, Nicola Longo, Hope Northrup, Stephanie Sacharow, Rani Singh, Janet A Thomas, Jerry Vockley, Roberto T Zori, Kaleigh Bulloch Whitehall, Joshua Lilienstein, Kristin Lindstrom, Drew G Levy, Shaun Jones, Barbara K Burton

Faculty, Staff and Student Publications

Phenylketonuria (PKU) is a genetic disorder caused by deficiency of the enzyme phenylalanine hydroxylase (PAH), which results in phenylalanine (Phe) accumulation in the blood and brain, and requires lifelong treatment to keep blood Phe in a safe range. Pegvaliase is an enzyme-substitution therapy approved for individuals with PKU and uncontrolled blood Phe concentrations (>600 μmol/L) despite prior management. Aggregated results from the PRISM clinical trials demonstrated substantial and sustained reductions in blood Phe with a manageable safety profile, but also noted individual variation in time to and dose needed for a first response. This analysis reports longer-term aggregate findings …

Open Tibial Shaft Fracture Fixation Strategies: Intramedullary Nailing, External Fixation, And Plating, Michelle Shen, Nirmal Tejwani

Faculty, Staff and Student Publications

Tibial shaft fractures are one of the most common orthopaedic injuries. Open tibial shaft fractures are relatively common because of the paucity of soft tissue surrounding the bone. Despite the prevalence of these injuries, the optimal fixation strategy is still a topic of debate. The purpose of this article was to review the current literature on open tibial shaft fracture fixation strategies including intramedullary nailing, external fixation, and plating.

Insurance Coverage During Transitions: Evidence From Medicaid Automatic Enrollment For Children Receiving Supplemental Security Income, Stephanie Rennane, Danielle Sobol, Bradley D Stein, Andrew Dick

Faculty, Staff and Student Publications

OBJECTIVES: To analyze relationships between Medicaid automatic enrollment for child Supplemental Security Income (SSI) recipients and health insurance coverage during transitions.

DATA SOURCES AND STUDY SETTING: Medical Expenditure Panel Study, 2000-2020 and National Survey for Children with Special Health Care Needs, 2001-2010.

STUDY DESIGN: Leveraging variation in SSI-Medicaid automatic enrollment status across regions and over time, we estimate a regression model to quantify associations between automatic enrollment and insurance coverage. We validate our findings in the NS-CSHCN.

DATA COLLECTION: Our sample includes children receiving SSI for a disability. We also analyze a subsample of children newly enrolled in SSI.

PRINCIPAL …

The Unusual Substrate Specificity Of Escherichia Coli Cardiolipin Synthase C Does Not Require The Product Of The Transcriptionally Engaged Ymdb Gene, Katsuhiro Sawasato, Mikhail Bogdanov

Faculty, Staff and Student Publications

Polycistronic transcription and translation of ymdB-clsC have been thought to be required for full activity of ClsC. The authentic initiation codon of the clsC gene is present within the open reading frame of the upstream located ymdB gene. ClsC translated from authentic initiation codon drives cardiolipin (CL) synthesis without transcriptionally paired YmdB. YmdB is not necessary for the substrate specificity of ClsC utilizing phosphatidylethanolamine (PE) as a co-substrate.

A Novel Missense Variant Located Within The Zinc Finger Domain Of The Gli3 Gene Was Identified In A Vietnamese Pedigree With Index Finger Polydactyly, Thy Ngoc Nguyen, Giang Son Tran, Hai Duc Hoang, Long Giang Nguyen

Faculty, Staff and Student Publications

BACKGROUND: Polydactyly, particularly of the index finger, remains an intriguing anomaly for which no specific gene or locus has been definitively linked to this phenotype. In this study, we conducted an investigation of a three-generation family displaying index finger polydactyly.

METHODS: Exome sequencing was conducted on the patient, with a filtration to identify potential causal variation. Validation of the obtained variant was conducted by Sanger sequencing, encompassing all family members.

RESULTS: Exome analysis uncovered a novel heterozygous missense variant (c.1482A>T; p.Gln494His) at the zinc finger DNA-binding domain of the GLI3 protein within the proband and all affected family members. …

Common Epilepsy Variants From The General Population Are Not Associated With Epilepsy Among Individuals With Tuberous Sclerosis Complex, Melissa A Richard, Philip J Lupo, Erik A Ehli, Mustafa Sahin, Darcy A Krueger, Joyce Y Wu, Elizabeth M Bebin, Kit Sing Au, Hope Northrup, Laura S Farach

Faculty, Staff and Student Publications

Common genetic variants identified in the general population have been found to increase phenotypic risks among individuals with certain genetic conditions. Up to 90% of individuals with tuberous sclerosis complex (TSC) are affected by some type of epilepsy, yet the common variants contributing to epilepsy risk in the general population have not been evaluated in the context of TSC-associated epilepsy. Such knowledge is important to help uncover the underlying pathogenesis of epilepsy in TSC which is not fully understood, and critical as uncontrolled epilepsy is a major problem in this population. To evaluate common genetic modifiers of epilepsy, our study …

From “Life As Lived” To “Life As Text”: Gendered Geographies Of Diaspora And Exile In Clément Baloup’S Vietnamese Memories, Jennifer Howell

Faculty Publications – Languages, Literatures, and Cultures

Baloup’s approach to using personal narratives in graphic novels transcends the specific realm of refugee comics or human rights campaigns, yet it faces challenges when attempting to bridge the gap between the intimate narratives of refugees and a broader commercial audience. Blurring the lines between autobiography, historiography, reportage, testimony, and docufiction, Vietnamese Memories retraces the global dimensions of the Vietnamese diaspora while engaging with the representation of transgenerational trauma in ways that reflect the diversity of the Viet Kieu experience. Transitioning from family history in the first volume to inferred advocacy in the third, Baloup’s exploration and graphic representation of …

Incidence And Factors In Delayed Neurological Deficits After Subarachnoid Hemorrhage In Mice, William Wroe, Ari Dienel, Sungha Hong, Kanako Matsumura, Jose Guzman, Kiara Torres, Angelica Bernal, Hussein A Zeineddine, Peeyush Thankamani Pandit, Spiros L Blackburn, Devin W Mcbride

Faculty, Staff and Student Publications

Background: Delayed cerebral ischemia (DCI) is one of the most feared complications in aneurysmal subarachnoid hemorrhage (SAH). Animal models are crucial to studying the disease mechanisms and potential treatments. DCI in rodents was thought to not exist; herein we examine literature and our experience with DCI in rodents.

Methods: Daily behavioral performance was assessed every day from day 1 to up to 7 days post-SAH on mice from 5 different studies that used the endovascular perforation model. Performance was graded using an 8-test sensorimotor neuroscore previously described. The daily neuroscore was then used to identify the incidence and timing of …

Characterization Of Disease Burden, Treatment And Comorbidities In A Large, Real-World Cohort Of Patients With Atopic Dermatitis: The Corevitas Atopic Dermatitis Registry, Jonathan I Silverberg, Angel Cronin, Eric A Jones, Swapna S Dave, Robert R Mclean, Jeffrey Greenberg, Bruce Strober, Thomas Bieber, Melinda Gooderham, Amy S Paller, Eric L Simpson

Faculty, Staff and Student Publications

No abstract provided.

Confirmation And Inheritance Of Glufosinate Resistance In An Amaranthus Palmeri Population From North Carolina, Eric A L Jones, Jeffrey C Dunne, Charles W Cahoon, Katherine M Jennings, Ramon G Leon, Wesley J Everman

Faculty, Staff and Student Publications

A putative glufosinate‐resistant Amaranthus palmeri population was reported in 2015 in Anson County, North Carolina. The results from dose–response assays conducted in the field suggested plants were surviving lethal rates of glufosinate. Dose–response assays conducted in the glasshouse determined the Anson County accession exhibited reduced susceptibility to glufosinate compared to three glufosinate‐susceptible populations. The LD50 values (210–316 g ai ha−1) for the Anson County population were always higher than the LD50 values (118–158 g ai ha−1) for the tested susceptible populations from the dose–response assays. Anson County plants that survived lethal glufosinate rates were reciprocally crossed with susceptible plants to …