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Individuals With Jak1 Variants Are Affected By Syndromic Features Encompassing Autoimmunity, Atopy, Colitis, And Dermatitis, Michael E Horesh, Marta Martin-Fernandez, Conor Gruber, Sofija Buta, Tom Le Voyer, Eve Puzenat, Harry Lesmana, Yiming Wu, Ashley Richardson, David Stein, Stephanie Hodeib, Mariam Youssef, Jacob A Kurowski, Elizabeth Feuille, Luis A Pedroza, Ramsay L Fuleihan, Alexandria Haseley, Alain Hovnanian, Pierre Quartier, Jérémie Rosain, Georgina Davis, Daniel Mullan, O'Jay Stewart, Roosheel Patel, Angelica E Lee, Rebecca Rubinstein, Leyla Ewald, Nikhil Maheshwari, Virginia Rahming, Ivan K Chinn, James R Lupski, Jordan S Orange, Vanessa Sancho-Shimizu, Jean-Laurent Casanova, Noura S Abul-Husn, Yuval Itan, Joshua D Milner, Jacinta Bustamante, Dusan Bogunovic Jun 2024

Individuals With Jak1 Variants Are Affected By Syndromic Features Encompassing Autoimmunity, Atopy, Colitis, And Dermatitis, Michael E Horesh, Marta Martin-Fernandez, Conor Gruber, Sofija Buta, Tom Le Voyer, Eve Puzenat, Harry Lesmana, Yiming Wu, Ashley Richardson, David Stein, Stephanie Hodeib, Mariam Youssef, Jacob A Kurowski, Elizabeth Feuille, Luis A Pedroza, Ramsay L Fuleihan, Alexandria Haseley, Alain Hovnanian, Pierre Quartier, Jérémie Rosain, Georgina Davis, Daniel Mullan, O'Jay Stewart, Roosheel Patel, Angelica E Lee, Rebecca Rubinstein, Leyla Ewald, Nikhil Maheshwari, Virginia Rahming, Ivan K Chinn, James R Lupski, Jordan S Orange, Vanessa Sancho-Shimizu, Jean-Laurent Casanova, Noura S Abul-Husn, Yuval Itan, Joshua D Milner, Jacinta Bustamante, Dusan Bogunovic

Faculty, Staff and Students Publications

Inborn errors of immunity lead to autoimmunity, inflammation, allergy, infection, and/or malignancy. Disease-causing JAK1 gain-of-function (GoF) mutations are considered exceedingly rare and have been identified in only four families. Here, we use forward and reverse genetics to identify 59 individuals harboring one of four heterozygous JAK1 variants. In vitro and ex vivo analysis of these variants revealed hyperactive baseline and cytokine-induced STAT phosphorylation and interferon-stimulated gene (ISG) levels compared with wild-type JAK1. A systematic review of electronic health records from the BioME Biobank revealed increased likelihood of clinical presentation with autoimmunity, atopy, colitis, and/or dermatitis in JAK1 variant-positive individuals. Finally, …


Theology And Tolkien: Practical Theology (2023), Edited By Douglas Estes, Lisa Coutras Jun 2024

Theology And Tolkien: Practical Theology (2023), Edited By Douglas Estes, Lisa Coutras

Journal of Tolkien Research

Book review, by Lisa Coutras, of Theology and Tolkien: Practical Theology (2023), edited by Douglas Estes


Holy Cross Magazine, Vol. 58, No. 2, Spring/Summer 2024, College Of The Holy Cross Jun 2024

Holy Cross Magazine, Vol. 58, No. 2, Spring/Summer 2024, College Of The Holy Cross

Holy Cross Magazine

What is Belonging — And Why Does it Matter in Today’s Divided, Lonely World?
It’s not a buzzword, a checkbox or a synonym for diversity and inclusion. Psychologists and experts explain what belonging is, how it matters to you and why it’s more important than ever.
Feature by Maura Sullivan Hill

A Walk Long-Delayed
For members of the class of 2024, perseverance paid off, as they experienced their first traditional graduation following a nontraditional end of high school and beginning of college.
Reflection by Diana Chavez Cruz ’24

‘This Masterpiece’
Inside St. Joseph Memorial Chapel at 100.
Feature by Melissa …


Is The Lecture Dead? Medical Students' Perspectives On Reconciling Live Lectures And 21st-Century Learning, Vamsi Chodisetty, Amish Jain, Landry Cowles, Nate Cowan, Marisa Imbroane, Hejin Jeong, Sarah Fry, Amy L. Wilson-Delfosse Jun 2024

Is The Lecture Dead? Medical Students' Perspectives On Reconciling Live Lectures And 21st-Century Learning, Vamsi Chodisetty, Amish Jain, Landry Cowles, Nate Cowan, Marisa Imbroane, Hejin Jeong, Sarah Fry, Amy L. Wilson-Delfosse

Student Scholarship

This chapter describes a literature review evaluating five innovative health professions education approaches to large group teaching and presents student perspectives regarding their implementation.


Building Trust: The Role Of Place-Based Consciousness In Vaccine Hesitancy, Ramsey W. Ash Jun 2024

Building Trust: The Role Of Place-Based Consciousness In Vaccine Hesitancy, Ramsey W. Ash

Quantitative Social Science Undergraduate Senior Theses

Vaccine hesitancy poses a threat to public health initiatives of the 21st century. Following a stark divide in the rural/urban COVID-19 vaccine uptake and harsh disparities between these areas in COVID-19 moralities and morbidities, further understanding of the drivers of vaccine hesitancy are needed. This study makes use of the framework of place-based consciousness (PBC), pioneered by scholars of rural political science, such as Katherine Cramer, to explore this phenomenon as a mechanism by which to understand vaccine hesitancy. To examine this, an experimental survey was distributed to 300 Americans (150 rural and 150 urban) that inquired about their PBC, …


Open Syllabus, Dorina Tila Jun 2024

Open Syllabus, Dorina Tila

Open Educational Resources

This is an open syllabus for Principles of Macroeconomics course.


English Professor's First Novel Draws Widespread Praise, Edwin Smith Jun 2024

English Professor's First Novel Draws Widespread Praise, Edwin Smith

University of Mississippi News

OXFORD, Miss. – A University of Mississippi English professor's debut novel is earning universal praise from critics.


Fostering Self-Reflection On Library Instruction: Testing A Peer Observation Instrument Focused On Questioning Strategies, Eric Silberberg Jun 2024

Fostering Self-Reflection On Library Instruction: Testing A Peer Observation Instrument Focused On Questioning Strategies, Eric Silberberg

Publications and Research

This study demonstrates that a library instruction observation instrument can effectively foster critical self-reflection among academic library faculty and staff on their teaching practices. The paper outlines the instrument's design, which gathers low inference observations on instructors’ use of questioning as a pedagogical strategy based on recommendations from the LIS and education literature. To test and refine the instrument's design, the instructors’ utilised the instrument to collect data from classes taught by five participating instructors, who, during post-observation interviews, engaged in thoughtful reflections on their class planning, student participation, and teaching philosophy. They also provided valuable critiques of the usefulness …


The Impact Of Artificial Intelligence On The Acquisition Of A Dental Practice, Lubna Ghassab Nicola Alhalaseh Jun 2024

The Impact Of Artificial Intelligence On The Acquisition Of A Dental Practice, Lubna Ghassab Nicola Alhalaseh

Harrisburg University Dissertations and Theses

This paper discusses the impact of adapting Artificial Intelligence in the acquisition of a dental office on the Triple Constraints of Project Management in the Iron Triangle, Schedule, Budget and Scope. The study also aims to examine the value that Artificial Intelligence adds to the startup process compared to traditional methods. Modern project management aims to integrate Artificial Intelligence in the gathering, processing, and integration of project-related data to where value creation through innovation is not just an aspiration but a tangible reality. Dentistry is no exclusion of this, implementing Artificial Intelligence has been a trend and Artificial Intelligence has …


In-Service Efl Practitioners’ Use Of Corpora In Private English Language Schools, Cathryn Bennett Jun 2024

In-Service Efl Practitioners’ Use Of Corpora In Private English Language Schools, Cathryn Bennett

Irish Journal of Academic Practice

Despite the call for corpora to be integrated into the English as a Foreign Language (EFL) classroom, hesitancy amongst teachers is still reported within research (Poole, 2020). Teachers with the most challenging conditions for integrating corpora are private language schoolteachers who often teach a high number of hours minimising their opportunities towards professional development (Stanley, 2016; Mercer, 2020). Frankenberg-Garcia (2012) recommends that small corpus activities could bring corpora into their classrooms despite required syllabi. Therefore, a five-week training programme which introduces corpora and helps teachers to design these short corpus activities was designed. 19 in-service teachers from across the globe …


Abstract Book (Pdf), Department Of Psychiatry Jun 2024

Abstract Book (Pdf), Department Of Psychiatry

Dept. of Psychiatry Research Symposium

Abstract book for the 2nd Annual Department of Psychiatry Research Symposium held June 2024.
Abstracts are in alphabetical by last name of the lead author.

Accessibility statement: The attached document has been formatted to meet PDF/UA v1 accessibility compliance standards. Please contact [email protected] if further assistance is needed.


Forest Fire Prediction In Northwest Jordan, Hashem Alshraifat, Hussam Al-Bilbisi Jun 2024

Forest Fire Prediction In Northwest Jordan, Hashem Alshraifat, Hussam Al-Bilbisi

An-Najah University Journal for Research - B (Humanities)

Fire hazards are common in forests of Jordan. For this reason, the study was focused on the different methods to analyze the human and natural characteristics of northwest Jordan for predicting the possibility of forest fire in the study area. The methodology was applied by using satellite images, Geographic Information System (GIS), Analytical Hierarchy Process (AHP) and Digital Elevation Model (DEM) as well as different extracted data from various sources which is important to produce forest fire probability map. The results of the study showed that about 820 km2, which represent 34% of the area is vulnerable of fires. …


Impact Of Employing Artificial Intelligence On Media Institutions In Palestine From The Viewpoint Of Those In Charge Of Communication, Mahmoud M. Khlouf Jun 2024

Impact Of Employing Artificial Intelligence On Media Institutions In Palestine From The Viewpoint Of Those In Charge Of Communication, Mahmoud M. Khlouf

An-Najah University Journal for Research - B (Humanities)

The study investigates the impact of employing artificial intelligence on media institutions in Palestine from the viewpoint of those in charge of communication, while highlighting the different perspectives expressed by those in charge of communication and technology experts in these institutions. The study, which was applied to the occupied Palestinian territories (West Bank and Gaza Strip), showed that 40% of the respondents believed that all those involved in the media industry including (journalists, directors of departments related to media work, editor-in-chiefs, editor-in-chiefs, heads of media institutions, Engineers...etc.) need training courses to promote their artificial intelligence skills. The results also showed …


Extralimital Records Of The Great Kiskadee, P. Allen Woodliffe Jun 2024

Extralimital Records Of The Great Kiskadee, P. Allen Woodliffe

Ontario Birds

No abstract provided.


Aberrant Colouration In Some Ontario Birds, Kenneth F. Abraham, Chris J. Risley, D.V. Chip Weseloh Jun 2024

Aberrant Colouration In Some Ontario Birds, Kenneth F. Abraham, Chris J. Risley, D.V. Chip Weseloh

Ontario Birds

No abstract provided.


Thick-Billed Kingbird At Presqu'ile Provincial Park: New To Ontario, Bruce M. Labio Jun 2024

Thick-Billed Kingbird At Presqu'ile Provincial Park: New To Ontario, Bruce M. Labio

Ontario Birds

No abstract provided.


The Discovery Of A Great Kiskadee At Rondeau Provincial Park: New To Ontario And Canada, Laura Rainbow Dragon Jun 2024

The Discovery Of A Great Kiskadee At Rondeau Provincial Park: New To Ontario And Canada, Laura Rainbow Dragon

Ontario Birds

No abstract provided.


A Ground-Nesting Bald Eagle In Ontario, Daniel J. Riley Jun 2024

A Ground-Nesting Bald Eagle In Ontario, Daniel J. Riley

Ontario Birds

No abstract provided.


White-Crowned Pigeon: New To Ontario And Canada, Bruce M. Di Labio, Ross Harris Jun 2024

White-Crowned Pigeon: New To Ontario And Canada, Bruce M. Di Labio, Ross Harris

Ontario Birds

No abstract provided.


Nesting Of American White Pelicans In Lake Erie, 2019, D.V. Chip Weseloh, Adam Byrne, Doug Crump, David J. Moore Jun 2024

Nesting Of American White Pelicans In Lake Erie, 2019, D.V. Chip Weseloh, Adam Byrne, Doug Crump, David J. Moore

Ontario Birds

No abstract provided.


Effects Of Double-Crested Cormorants On A Nest Tree At A Newly Formed Colony, Justin Peter Jun 2024

Effects Of Double-Crested Cormorants On A Nest Tree At A Newly Formed Colony, Justin Peter

Ontario Birds

No abstract provided.


Distinguished Ornithologist: Margaret Bain, Glenn Coady Jun 2024

Distinguished Ornithologist: Margaret Bain, Glenn Coady

Ontario Birds

No abstract provided.


Highly Nutritious Marsh Vegetation As A Magnet For Swans, Harry G. Lumsden, Dave Mclachlin, Gerry Markhoff, Allan Scott Jun 2024

Highly Nutritious Marsh Vegetation As A Magnet For Swans, Harry G. Lumsden, Dave Mclachlin, Gerry Markhoff, Allan Scott

Ontario Birds

No abstract provided.


Detectability Of Upland Sandpipers In A Rural Ontario Landscape, Daniel Chronowic, Carl Wegenschimmel, Walter Wehtje, Erica Nol Jun 2024

Detectability Of Upland Sandpipers In A Rural Ontario Landscape, Daniel Chronowic, Carl Wegenschimmel, Walter Wehtje, Erica Nol

Ontario Birds

No abstract provided.


Little Gull At Lake Simcoe, Ontario And Review Of Status In Ontario, James Coey Jun 2024

Little Gull At Lake Simcoe, Ontario And Review Of Status In Ontario, James Coey

Ontario Birds

No abstract provided.


First Successful Nesting Of Fish Crow In Ontario And Canada, Lucio ‘Luc’ Fazio Jun 2024

First Successful Nesting Of Fish Crow In Ontario And Canada, Lucio ‘Luc’ Fazio

Ontario Birds

No abstract provided.


In Memoriam: James D Rising, Nancy J. Flood Jun 2024

In Memoriam: James D Rising, Nancy J. Flood

Ontario Birds

No abstract provided.


How Do Recent Changes In Lake Erie Affect Birds? Part Three: Type-E Botulism, Doug Tozer, Gregor Beck Jun 2024

How Do Recent Changes In Lake Erie Affect Birds? Part Three: Type-E Botulism, Doug Tozer, Gregor Beck

Ontario Birds

No abstract provided.


Letter To The Editors: Comment On Burbidge (2018), Anthony X. Hertzel Jun 2024

Letter To The Editors: Comment On Burbidge (2018), Anthony X. Hertzel

Ontario Birds

No abstract provided.


Ontario Bird Records Committee Report For 2018, Mike V.A. Burrell, Barbara N. Charlton, Kenneth G.D. Burrell, Joshua D. Vandermeulen, Amanda C. Guercio, Blake A. Mann, Donald A. Sutherland, Paul D. Pratt, William G. Lamond Jun 2024

Ontario Bird Records Committee Report For 2018, Mike V.A. Burrell, Barbara N. Charlton, Kenneth G.D. Burrell, Joshua D. Vandermeulen, Amanda C. Guercio, Blake A. Mann, Donald A. Sutherland, Paul D. Pratt, William G. Lamond

Ontario Birds

No abstract provided.