Digital Commons Network^™

Intersectional Analysis Of Vaccination Inequity Among Individuals With Disabilities In The United States During Covid-19 Pandemic, Philip Ndoki Ndoki

Walden Dissertations and Doctoral Studies

This study was an investigation of how disability status, types, sociodemographic indicators, and reasons for not receiving vaccinations influenced COVID-19 vaccination rates among individuals with disabilities in the United States. Despite efforts, vaccination disparities persisted, necessitating an understanding of barriers to uptake. Using intersectionality theory and the social determinants of health framework, this study examined the impact of marginalized identities and structural inequalities. Key questions included the association between disability status and vaccination uptake, differences among disability types moderated by sociodemographic factors, and the interaction between disability status and reasons for not vaccinating. Household Pulse Survey data from the US …

Context-Dependent T-Box Transcription Factor Family: From Biology To Targeted Therapy, Siwen Li, Xiangyuan Luo, Mengyu Sun, Yijun Wang, Zerui Zhang, Junqing Jiang, Dian Hu, Jiaqian Zhang, Zhangfan Wu, Yufei Wang, Wenjie Huang, Limin Xia

Faculty, Staff and Student Publications

T-BOX factors belong to an evolutionarily conserved family of transcription factors. T-BOX factors not only play key roles in growth and development but are also involved in immunity, cancer initiation, and progression. Moreover, the same T-BOX molecule exhibits different or even opposite effects in various developmental processes and tumor microenvironments. Understanding the multiple roles of context-dependent T-BOX factors in malignancies is vital for uncovering the potential of T-BOX-targeted cancer therapy. We summarize the physiological roles of T-BOX factors in different developmental processes and their pathological roles observed when their expression is dysregulated. We also discuss their regulatory roles in tumor …

Impact Of Isotype On The Mechanism Of Action Of Agonist Anti-Ox40 Antibodies In Cancer: Implications For Therapeutic Combinations, Jane E Willoughby, Lang Dou, Sabyasachi Bhattacharya, Heather Jackson, Laura Seestaller-Wehr, David Kilian, Laura Bover, Kui S Voo, Kerry L Cox, Tom Murray, Mel John, Hong Shi, Paul Bojczuk, Junping Jing, Heather Niederer, Andrew J Shepherd, Laura Hook, Stephanie Hopley, Tatyana Inzhelevskaya, Chris A Penfold, C Ian Mockridge, Vikki English, Sara J Brett, Roopa Srinivasan, Christopher Hopson, James Smothers, Axel Hoos, Elaine Paul, Stephen L Martin, Peter J Morley, Niranjan Yanamandra, Mark S Cragg

Faculty, Staff and Student Publications

BACKGROUND: OX40 has been widely studied as a target for immunotherapy with agonist antibodies taken forward into clinical trials for cancer where they are yet to show substantial efficacy. Here, we investigated potential mechanisms of action of anti-mouse (m) OX40 and anti-human (h) OX40 antibodies, including a clinically relevant monoclonal antibody (mAb) (GSK3174998) and evaluated how isotype can alter those mechanisms with the aim to develop improved antibodies for use in rational combination treatments for cancer.

METHODS: Anti-mOX40 and anti-hOX40 mAbs were evaluated in a number of in vivo models, including an OT-I adoptive transfer immunization model in hOX40 knock-in …

Author Correction: Distinct Molecular And Immune Hallmarks Of Inflammatory Arthritis Induced By Immune Checkpoint Inhibitors For Cancer Therapy, Sang T Kim, Yanshuo Chu, Mercy Misoi, Maria E Suarez-Almazor, Jean H Tayar, Huifang Lu, Maryam Buni, Jordan Kramer, Emma Rodriguez, Zulekha Hussain, Sattva S Neelapu, Jennifer Wang, Amishi Y Shah, Nizar M Tannir, Matthew T Campbell, Don L Gibbons, Tina Cascone, Charles Lu, George R Blumenschein, Mehmet Altan, Bora Lim, Vincente Valero, Monica E Loghin, Janet Tu, Shannon N Westin, Aung Naing, Guillermo Garcia-Manero, Noha Abdel-Wahab, Hussein A Tawbi, Patrick Hwu, Isabella C Glitza Oliva, Michael A Davies, Sapna P Patel, Jun Zou, Andrew Futreal, Adi Diab, Linghua Wang, Roza Nurieva

Faculty, Staff and Student Publications

No abstract provided.

Optimizing Associative Memory In Autistic And Non-Autistic Adults: Retrieval Practice, Post-Retrieval Feedback, And Gesture, Brianna E. Cairney

LSU Doctoral Dissertations

Associative memory—or the ability to form a memory representation linking two previously unrelated concepts—is a critical aspect of learning. This work provides insight into strategies that can be used to support associative memory, their underlying mechanisms, and their effectiveness in autistic and non-autistic learners. Chapter 1 demonstrates that iconic gestures can be used as a tool to enhance associative memory by increasing word concreteness and imageability. This effect was eliminated when the iconic gestures were interspersed with ambiguous nonsense gestures, suggesting a boundary on these benefits that depends on listener expectations regarding gesture clarity. However, it remains unknown whether gestures …

Caregiver Recruitment Strategies For Interventions Designed To Optimize Transitions From Hospital To Home: Lessons From A Randomized Trial, Allison M Gustavson, Molly J Horstman, Jodie A Cogswell, Diane E Holland, Catherine E Vanderboom, Jay Mandrekar, William S Harmsen, Brystana G Kaufman, Cory Ingram, Joan M Griffin

Faculty, Staff and Students Publications

Challenges to recruitment of family caregivers exist and are amplified when consent must occur in the context of chaotic healthcare circumstances, such as the transition from hospital to home. The onset of the COVID-19 pandemic during our randomized controlled trial provided an opportunity for a natural experiment exploring and examining different consent processes for caregiver recruitment. The purpose of this publication is to describe different recruitment processes (in-person versus virtual) and compare diversity in recruitment rates in the context of a care recipient's hospitalization. We found rates of family caregiver recruitment for in-person versus virtual were 28% and 23%, respectively …

Tolkien: Voyage En Terre Du Milieu (2019), Ed. By Vincent Ferré And Frédéric Manfrin, Deidre A. Dawson

Journal of Tolkien Research

Book review, by Deidre A. Dawson, of Tolkien: Voyage en Terre du Milieu (2019) ed. by Vincent Ferré and Frédéric Manfrin

How To Be In Two Places At Once: A Search For The Immersive Experience In Renaissance Music And Visual Arts., Andrew Hallock

Journal of Network Music and Arts

Immersion is a hot topic, but it is often invoked in a vague or shallow way. This essay aims to arrive at a more nuanced consideration of the immersive experience by presenting some perhaps surprising arguments from the past—from Renaissance music and visual arts—drawing parallels with our own time, and positing that the Network Arts can take inspiration from this history to enhance its own immersive endeavours. Four interrelated topics serve as the basis for this investigation: miniature devotionalia, polyphonic canons, anamorphic puzzles, and early cosmology. By using perspective to disclose hidden meanings, ideas, and realities, these varied practices draw …

The Lived Clinical Experiences Of Expatriate Athletic Trainers, Emily K. Mulkey, Elizabeth R. Neil, Trisha Cousins, Mary Murray

Internet Journal of Allied Health Sciences and Practice

One of the ways that healthcare systems have adapted to the needs of patient care is to expand the role of allied healthcare professionals. The utilization of these clinicians, with wide-ranging skill sets, allows for increased adaptability and improved patient outcomes.¹ Expansion of physician reach through allied health professions provides improved connectivity to patients.² While medical communities all have a common goal, the healthcare system varies among nations in terms of the representation of allied healthcare professions.² Within the United States (US), one of the most versatile allied health professions is athletic training. With a skill set …

“Who All Gon Be There?”: On Blackness, Transness, And K-12 Pedagogies For [Black] Trans Futures, Shea W. Martin

Journal of Queer and Trans Studies in Education

Grounded in trans-of-color critique and Black trans studies, this theoretical meditation reckons with the impossibility of Black trans safety, recognition, and futurity within our U.S. K-12 educational landscape. Situated in a “post-Transgender Tipping Point” sociopolitical landscape, I explore how these limitations contribute to Black trans youth’s disparate experiences in today’s schools, particularly with attention to the [in]effectiveness of existing queer and trans pedagogies. In an attempt to locate what is deemed possible for Black trans youth in imagined educational futures, I discuss trends within select K-12 trans pedagogical scholarship through which I explore questions related to authorship, reflexivity, and intersectional …

Mid- To Late-Miocene Hypogene Speleogenesis Tied To The Tectonic History Of The Central Basin And Range Province, Usa, Louise D. Hose, Victor Polyak, Harvey R. Duchene, J. Douglas Powell, Leslie A. Melim, Gretchen M. Baker, Donald G. Davis, Yemane Asmerom

International Journal of Speleology

Twenty-five caves displaying evidence of hypogene speleogenesis in White Pine County, Nevada, were studied between May 2022 and October 2023. Results demonstrate that the central Basin and Range Province is a major hypogenic cave region with speleogenesis dating back to the Middle Miocene. The U-Pb radiometric dates of cave mammillaries obtained so far cover a wide span of time, ranging between 14 Ma to 2 Ma. Tectonic shearing along the Snake Range Décollement up to about 22 Ma probably brackets the maximum age of speleogenesis. Thus, speleogenesis began between 22-14 Ma, which predates most of the Basin and Range extensional …

The Concept Of Chinese Classical Xiaoshuo And Its Japanese Counterpart And Modern Transformation, Shu Jiang

Theoretical Studies in Literature and Art

The concept of xiaoshuo was introduced as the equivalent to Western terms of “romance” and “novel”, and the role of Japan and the culture in Meiji Japan as a mediator was crucial. This translation was notably observed in English-Chinese dictionaries compiled by missionaries, particularly in the English and Chinese Dictionary: With the Punti and Mandarin Pronunciation compiled by Wilhelm Lobscheid, where xiaoshuo was rendered as “romance” and “novel”, subsequently impacting Yan Huiqing's An English and Chinese Standard Dictionary. Tsubouchi Shōyō distinguished between “romance” and “novel” in his work The Essence of Novel, while Lu Xun provided academic definitions …

Boredom And Its Relationship With Experiential Avoidance Styles As Perceived By The Students Of Al-Quds Open University, Zuhair El-Nawajah

Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث

The study aimed to identify the levels and correlation between boredom and experiential avoidance styles, and examine the differences in the experiential avoidance styles in terms of gender. The study sample consisted of (124) males and females from Al-Quds open university. To achieve the objectives of the study, the researcher used two instruments: the boredom scale prepared by (Fahlman,2013) and the experiential avoidance styles scale (Gámez, et al, 2011). The study concluded that the total degree of boredom was moderate. Stress aversion, distress tolerance, evasive behavior and distraction were high, while procrastination and denial were moderate. There was also a …

An Evaluation Study Of The Questions Of The Palestinian General Secondary School Certificate Exams In The Subject Of Islamic Education For The Years (2007-2020) In The Light Of The Cognitive Levels Of The Bloom Pyramid, Majdi Joyousi, Afif Zeidan, Hisham Shanaa

Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث

The current study aimed at analyzing and evaluating the questions of the Palestinian General Secondary School Certificate in the subject of Islamic education and indicating the degree of their representation of Bloom's levels of knowledge, and identifying the percentages obtained by each of the levels. Six levels (knowledge, comprehension, application, analysis, synthesis, and evaluation). The results of the study showed that the total number of high school exams questions for the year (2007-2020) is (466). Where the first level constituted comprehension and comprehension, which amounted to (37.1%), and the level of knowledge constituted a percentage of (36.7%) and the percentage …

Exploring Global Disparities In Tuberculosis Treatment And Outcomes: A Scoping Review Of Gender-Based Perspectives And Implications For Women’S Health, Colin Gordy, Dylan Barker, Marie Barnard, Sudeshna Roy

Faculty and Student Publications

This scoping review aims to explore the gender-specific disparities and highlight the unique disadvantages faced by women in the context of Tuberculosis (TB). By mapping the existing literature on women's experiences with TB, this review seeks to uncover the underlying factors contributing to these disparities and identify gaps in the current understanding. The goal is to inform future research and policymaking, ultimately improving TB prevention, treatment, and outcomes for women worldwide. Recognizing and addressing the specific needs and challenges of women is essential for achieving equitable and effective TB control.

Concolic Testing For Scripting Languages, Zhe Li

Dissertations and Theses

Scripting languages, such as JavaScript and Lua, are becoming more and more popular. They are typically easy to learn and use, making them accessible to a wide range of developers, even those with limited programming experience. Lua, for instance, is a lightweight, efficient, and versatile scripting language. It is designed to be easy to integrate into other systems and is often used as an embedded scripting language in larger applications such as NMap, which is a network scanning tool.

As another example, web front-end development with JavaScript (JS) is a popular choice for developers due to its ability to add …

Kaitlyn Mcneilly Gives To Gardner-Webb To Celebrate The University’S Impact On Her Life, Office Of University Communications

Gardner-Webb NewsCenter Archive

Kaitlyn McNeilly, 2015 alumna of Gardner-Webb, describes her four years at the University as “genuinely lifechanging.” An English major and native of Forest City, N.C., she expressed her deep appreciation for the faculty in her program. This year on Double Dawg Day, she made her first donation to the University, a gi! to honor and support the Department of English. She joined over 1,300 donors on that day to raise a record-breaking $1.4 million for the University’s academic and athletic programs, scholarships, and facilities.

Experimentation With Speech Recognition And Word Error Rates, Sarah Zelikovitz, Orit D. Gruber

Open Educational Resources

In this lab you will be using the speech recognition program in Windows. After the initial training session, you will proceed to conduct experiments to evaluate the accuracy of the speech program.

At the end of this lab, you will be able to answer the following questions:

What is the purpose of speech recognition programs ?

• What are some applications of speech recognition programs ?

• What is the metric to evaluate speech recognition programs?

• What parameters are used to test speech recognition programs?

Cover And Contents

Turkish Journal of Mathematics

No abstract provided.

On A Class Of Permutation Trinomials Over Finite Fields, Burcu Gülmez Temür, Buket Özkaya

Turkish Journal of Mathematics

In this paper, we study the permutation properties of the class of trinomials of the form f(x) = x4q+1 +λ1xq+4 +λ2x2q+3 ∈ Fq2 [x] , where λ1, λ2 ∈ Fq and they are not simultaneously zero. We find all necessary and sufficientconditions on λ1 and λ2 such that f(x) permutes Fq2 , where q is odd and q = 22k+1, k ∈ N.

Library Internal Reviews For Value Description And Strategic Planning, Holt Zaugg

Faculty Publications

In between university level assessments, the BYU Library conducts internal reviews of each library department, describing its value to the library and university, and providing recommendations for improvement. The process used a team of library employees in departments not under review and an external reviewer to conduct the internal review. Using a case-study approach, the development of an internal review system, its meta-evaluation at the end of its first cycle, and the on-going efforts to improve the internal review process are described. Using a graduate level evaluation class followed by a task force, changes were made to the internal review …

Schaechter Viswanath, Gitl, Sophia Maier Garcia

Bronx Jewish History Project

Gitl Schaechter Viswanath was born into a Yiddish-speaking family. Her father came from Romania to the United States in 1951, becoming a renowned Yiddish linguist and Columbia professor. He and his wife wanted to raise their children speaking Yiddish within a Yiddish community, and so they created this community with two other families living near one another on Bainbridge Avenue in the north-central Bronx, the Fishmans and the Gottesmans. The families were primarily secular but focused on Jewish culture and tradition.

Schaechter Viswanath attended PS 56 and describes the school and area as primarily Jewish. After school, she went to …

Serum From Patients With Cirrhosis Undergoing Liver Transplantation Induces Permeability In Human Pulmonary Microvascular Endothelial Cells, Michael Bokoch, Fengyun Xu, Krishna Govindaraju, Elliot Lloyd, Kyle Tsutsui, Rishi Kothari, Dieter Adelmann, Jérémie Joffre, Judith Hellman

Department of Anesthesiology Faculty Papers

INTRODUCTION: Patients with cirrhosis undergoing liver transplantation frequently exhibit systemic inflammation, coagulation derangements, and edema, indicating endothelial dysfunction. This syndrome may worsen after ischemia-reperfusion injury of the liver graft, coincident with organ dysfunction that worsens patient outcomes. Little is known about changes in endothelial permeability during liver transplantation. We hypothesized that sera from these patients would increase permeability in cultured human endothelial cells

METHODS: Adults with cirrhosis presenting for liver transplantation provided consent for blood collection during surgery. Sera were prepared at five time points spanning the entire operation. The barrier function of human pulmonary microvascular endothelial cells in culture …

A Systems Biology-Based Identification And In Vivo Functional Screening Of Alzheimer’S Disease Risk Genes Reveal Modulators Of Memory Function, Adam D Hudgins, Shiyi Zhou, Rachel N Arey, Michael G Rosenfeld, Coleen T Murphy, Yousin Suh

Faculty, Staff and Students Publications

Genome-wide association studies (GWASs) have uncovered over 75 genomic loci associated with risk for late-onset Alzheimer's disease (LOAD), but identification of the underlying causal genes remains challenging. Studies of induced pluripotent stem cell (iPSC)-derived neurons from LOAD patients have demonstrated the existence of neuronal cell-intrinsic functional defects. Here, we searched for genetic contributions to neuronal dysfunction in LOAD using an integrative systems approach that incorporated multi-evidence-based gene mapping and network-analysis-based prioritization. A systematic perturbation screening of candidate risk genes in Caenorhabditis elegans (C. elegans) revealed that neuronal knockdown of the LOAD risk gene orthologs vha-10 (ATP6V1G2), cmd-1 (CALM3), amph-1 (BIN1), …

Caitlin Clark And History, Richard C. Crepeau

On Sport and Society

Over the past several weeks one of the major stories in sport in the United States has been Caitlin Clark’s quest for the all-time scoring title in women’s college basketball. Clark with her high-level skills: shooting, passing, rebounding, and defense were a source of amazement to many, especially those for whom women’s basketball and women’s sport have been of marginal interest.

Sociology Between The Gaps Volume 9 (2024)

Sociology Between the Gaps: Forgotten and Neglected Topics

No abstract provided.

Development And Testing Of A Videogame Intervention For Improving The Health-Related Quality Of Life (Hrqol) Of Children With Cancer At A Tertiary Care Hospital In Pakistan: A Mixed Method Design, Sehrish Sajjad

Sigma Foundation for Nursing Research Grant Reports

The study aims to develop a videogame intervention for children (age 8-18 years) with cancer and test the clinical efficacy of the intervention with regards to cancer symptom management and HrQOL.

Human Centered Approaches And Taxonomies For Explainable Artificial Intelligence, Helen Sheridan, Emma Murphy, Dympna O'Sullivan

Conference papers

Recent interest within the research community related to explainable artificial intelligence (XAI) has led to a profuse amount of literature on the subject. Those who wish to tackle the domain from an HCI focus may be presented with overwhelming material, most of which does not pertain to human aspects of XAI. Taxonomies can serve to categorize a subject into topic areas and distill content into an overview of the field. This late breaking work intends to help those within the HCI community with a focus on XAI to understand relevant aspects of human centered XAI. We also present a taxonomy …

Robust Quantitative Photoacoustic Imaging For Colorectal Cancer Treatment Monitoring, Sitai Kou

McKelvey School of Engineering Graduate Student Theses & Dissertations

Colorectal cancer is the 2nd leading cause of cancer death in the United States and the incidence among population under 50 years old has been increasing for the past decade. Contrary to obvious vascular and morphological structures in pre-treatment colorectal cancer, during treatment and post-treatment colorectal cancer tissue often contains fibrosis and edema in tumor bed. These complications cause difficulties in evaluating tissue response to neoadjuvant chemoradiation therapy with MRI and endoscopy, leading to unnecessary resection of rectum, which increases healthcare cost and impacts patient quality of life. Photoacoustic (PA) imaging is a promising tool for observing blood distribution in …

Marketing In Higher Education: The Effects On The College Choice Experience Of First-Generation Latinx Students, David Cortez

Dissertations and Theses

The Latinx population in the United States has drastically increased over the last twenty years. During the same period, the number of first-generation Latinx students enrolling in higher education post-recession has also increased by as much as 1.5 million students. The expansion of the Latinx student population in Oregon has mirrored the national trend by exponentially increasing over the last 10 years. As the population of first-generation Latinx students grows, it becomes essential to explore the issues and barriers Latinx students face in making their college choices. Previous researchers have found that selecting the right institution is important to increase …