Digital Commons Network^™

Tractography-Based Modeling Explains Treatment Outcomes In Patients Undergoing Deep Brain Stimulation For Obsessive-Compulsive Disorder, Michelle Avendano-Ortega, Sarah Mckay, Kelly R Bijanki, Meghan E Robinson, Garrett Banks, Nicole Provenza, Eric A Storch, Wayne K Goodman, Andreas Horn, Sameer A Sheth

Faculty, Staff and Students Publications

BACKGROUND: Deep brain stimulation (DBS) is an established and expanding therapy for treatment-refractory obsessive-compulsive disorder. Previous work has suggested that a white matter circuit providing hyperdirect input from the dorsal cingulate and ventrolateral prefrontal regions to the subthalamic nucleus could be an effective neuromodulatory target.

METHODS: We tested this concept by attempting to retrospectively explain through predictive modeling the ranks of clinical improvement as measured by the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) in 10 patients with obsessive-compulsive disorder who underwent DBS to the ventral anterior limb of internal capsule with subsequent programming uninformed by the putative target tract.

RESULTS: Rank …

Transcriptomic Analysis Reveals The Anti-Cancer Effect Of Gestational Mesenchymal Stem Cell Secretome, Marcos Quintela, Jing Xiao, Seydou Yao, Richard H Finnell, Robert S Conlan, Lewis W Francis, Bruna Corradetti

Faculty, Staff and Students Publications

The environment created during embryogenesis contributes to reducing aberrations that drive structural malformations and tumorigenesis. In this study, we investigate the anti-cancer effect of mesenchymal stem cells (MSCs) derived from 2 different gestational tissues, the amniotic fluid (AF) and the chorionic villi (CV), with emphasis on their secretome. Transcriptomic analysis was performed on patient-derived AF- and CV-MSCs collected during prenatal diagnosis and identified both mRNAs and lncRNAs, involved in tissue homeostasis and inhibiting biological processes associated with the etiology of aggressive cancers while regulating immune pathways shown to be important in chronic disorders. Secretome enrichment analysis also identified soluble moieties …

Partial Models For Building Adaptive Model-Based Reinforcement Learning Agents

Defensive Publications Series

In neuroscience, one of the key behavioral tests for determining whether a subject of study exhibits model-based behavior is to study its adaptiveness to local changes in the environment. In reinforcement learning, however, recent studies have shown that modern model-based agents display poor adaptivity to such changes. The main reason for this is that modern agents are typically designed to improve sample efficiency in single task settings and thus do not take into account the challenges that can arise in other settings. In local adaptation settings, one particularly important challenge is in quickly building and maintaining a sufficiently accurate model …

Transfer Entropy In Graph Convolutional Neural Networks

Defensive Publications Series

Graph Convolutional Networks (GCN) are Graph Neural Networks where the convolutions are applied over a graph. In contrast to Convolutional Neural Networks, GCN’s are designed to perform inference on graphs, where the number of nodes can vary, and the nodes are unordered. In this study, we address two important challenges related to GCNs: i) oversmoothing; and ii) the utilization of node relational properties (i.e., heterophily and homophily). Oversmoothing is the degradation of the discriminative capacity of nodes as a result of repeated aggregations. Heterophily is the tendency for nodes of different classes to connect, whereas homophily is the tendency of …

Graph Neural Networks Do Not Always Oversmooth

Defensive Publications Series

Graph neural networks (GNNs) have emerged as powerful tools for processing relational data in applications. However, GNNs suffer from the problem of oversmoothing, the property that the features of all nodes exponentially converge to the same vector over layers, prohibiting the design of deep GNNs. In this work we study oversmoothing in graph convolutional networks (GCNs) by using their Gaussian process (GP) equivalence in the limit of infinitely many hidden features. By generalizing methods from conventional deep neural networks (DNNs), we can describe the distribution of features at the output layer of deep GCNs in terms of a GP: as …

Systems And Methods For Improved Image Stabilization, Ajit Ninan

Defensive Publications Series

A method for improved image stabilization may include shifting image data from a memory device integrated with a display device, where the image data represents motion of the display device and corresponds with a time of capture of the image data; analyzing the image data via a processor to determine a stabilization correction to apply to the image data, analyzing including, determining the stabilization correction to correct for a displacement of at least a portion of the image data; applying the determined stabilization correction to the image data stored in the memory device to achieve stabilized image data; and outputting …

Patterning Methods For 3d Liquid Crystal Polarization Hologram Optical Elements, Kellie Shaw

Defensive Publications Series

A method of forming a 3D liquid crystal polarization hologram optical element includes irradiating a liquid crystal composition with linearly polarized light, polymerizing the liquid crystal composition, and aligning liquid crystal polymers within the liquid crystal composition along predetermined orientations, where the aligning includes a process selected from point-by-point patterning, slit-by-slit patterning, layer-by-layer patterning, and volumetric patterning.

Case Report Of A Brief Modular Anxiety Intervention For Integrated Primary Care: Addressing Clinician Feasibility Concerns And Barriers To Using Manualized Treatments, Katherine Buckheit, Robyn L. Shepardson, Luke Mitzel, Risa B. Weisberg, Stephen A. Maisto, Jennifer Funderburk

The Journal of Integrated Primary Care

Individuals with anxiety symptoms commonly present in primary care settings and prefer behavioral health (versus pharmacotherapy) treatment, but behavioral health interventions are underutilized. Primary care behavioral health (PCBH) models, in which embedded behavioral health providers deliver behavioral treatment in primary care, may help address the gap in provision of anxiety treatment. However, evidence-based anxiety treatment options feasible for delivery in primary care are limited, and clinicians often report concerns about using manualized interventions. Recent recommendations by the U.S. Preventative Services Task Force to increase anxiety screening among adults in primary care may result in increased identification of individuals with anxiety …

The Effect Of Lighting In Color In The Interior Space Of The Residential Unit, Abd Elbary Eldininy Abd Elbary Eldininy

Journal of Engineering Research

ABSTRACT: Humanity is spending more and more time indoors, both at work and at home - with studies showing that we now spend 87% of our lives indoors. Residential environ ments both positively affect the mood and well-being of its occupants, just as places with poor and uncomfortable lighting and colors can make life miserable. This is why we are interested in this issue. The importance of knowing the issues of lighting and colors in order to obtain a well thought-out interior design. The interior designer has the ability to control in the quality of lighting of various types, artificial …

Light Structure Building Technology Towards Sustainable Environmental Design, Sally El-Sayed Prof. Dr. Mai Wahba Madkour2, Prof. Dr. Marwa Ahmed Kamer El-Dawla3

Journal of Engineering Research

The building and construction industry is one of the most important sectors globally , as it plays a vital role in providing housing and infrastructure that meets the needs of various communities , However , this industry is considered one of the largest contributors of negative environmental impacts in terms of consuming huge amounts of natural resources in an unsustainable manner and a subsequent increase in energy consumption .Therefore, it was necessary to find solutions and explore for new and sustainable construction methods to alleviate these problems .This research paper will focus on the use of light buildings and their …

Agile Vs Waterfall As An Approach For Effective Management Practices In Fit Out Projects (Preferences Of Project Managers), Moutaz M. El Baz 1

Journal of Engineering Research

Optimum time, cost & quality are the key objectives in managing fit-out projects. Waterfall and Agile are the most common approaches for achieving the project objectives. To determine the optimal managerial approach for fit-out projects, it was essential to study the project life cycle & phases, waterfall & agile methodologies & phases and the project management performance indicators. To achieve the research goals, a data gathering/analysis performed among three steps. Firstly, by performing qualitative research through semi-structured interviews with project management experts to verify the research hypothesis. Secondly, through studying the project & project management life cycle, phases and characteristics …

An Analytical Study Of Key Performance Indicators For Knowledge Management In Construction Companies, Marwa. M. Ahmed Ayman A.E. Othman, Essam Eldin. K. Mahrous

Journal of Engineering Research

The construction and building industry plays a pivotal role in both national and global economies, necessitating a focused approach in knowledge management (KM) strategies amid current market disruptions and economic uncertainties. For construction companies to plan and develop effective KM strategies, they must be measured and incorporated within the key performance indicators (KPIs) relevant to construction companies. This research paper aims to review literature on knowledge management performance indicators (KM PIs) and rank their importance within the KPIs of contracting companies. Statistical analysis revealed that previous studies neglect KM PIs, such as, as some important techniques for KM, such as …

Heritage Preservation In Egyptian Villages And Centers, Azza Elsakka Ahmed Abdalwahaab , Ebtehal Fady Shareef

Journal of Engineering Research

Heritage holds deep significance as a collective memory and a source of pride for any society. However, in today's world, it has evolved beyond its symbolic status and emerged as a crucial factor in human development across various dimensions. Preserving and restoring heritage has thus become an urgent issue that demands extensive cooperation between governments, international society, and community associations.

Evaluation Of The Built Environment Performance In Light Of Sustainable And Universal Design: Criteria And Methods, N.A.Mohamed E. A. Morghany, M. E. Khalil

Journal of Engineering Research

Egypt's Vision 2030 for Sustainable Development Strategy (SDS) emphasizes social inclusion and accessibility. The concept of Universal Design (UD) is crucial in achieving the goals of SDS by facilitating utilization and access to the built environment for all.

When Overextended Surface Allocation Turns To Groundwater: A Q Methodology Of Well Users In Oregon’S High Desert, Melissa Haeffner, Janet Cowal, Brandy Walker, Clare Mcclellan

Environmental Science and Management Faculty Publications and Presentations

As legal battles over surface water allocation in Klamath County, Oregon, USA have gained national attention, earning the name “Water Wars,” authorities have been increasingly turning to groundwater to compensate for water shortfalls. This case study aims to identify the nuanced perspectives of household groundwater well users who are affected by groundwater extraction. Using Q methodology, we uncover groundwater well users’ perceptions and to what extent they think water problems are dealt with fairly. We identify four water perspectives that differ in the degree to which respondents prioritize clean water accessibility, industry accountability, individual responsibility for water management, and trust …

Optimized Gadolinium-Do3a Loading In Raftpolymerized Copolymers For Superior Mr Imaging Of Aging Blood–Brain Barrier, Hunter A. Miller, Aaron Priester, Evan T. Curtis, Krista Hilmas, Ashleigh Abbott, Forrest Kievit, Anthony J. Covertine

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The development of gadolinium-based contrast agents (GBCAs) has been pivotal in advancing magnetic resonance imaging (MRI), offering enhanced soft tissue contrast without ionizing radiation exposure. Despite their widespread clinical use, the need for improved GBCAs has led to innovations in ligand chemistry and polymer science. We report a novel approach using methacrylate-functionalized DO3A ligands to synthesize a series of copolymers through direct reversible addition-fragmentation chain transfer (RAFT) polymerization. This technique enables precise control over the gadolinium content within the polymers, circumventing the need for subsequent conjugation and purification steps, and facilitates the addition of other components such as targeting ligands. …

Leading Through The Covid-19 Pandemic: Experiences Of Uk Executive Nurse Directors, Alison H James, Rebecca Dimond, Aled Jones, Dianne Watkins, Daniel Kelly

School of Nursing and Midwifery

AIM: To explore the challenges experienced by Executive Nurse Directors during the COVID-19 pandemic, and to inform future nursing leadership strategies.

DESIGN: A qualitative research project involving interviews with 21 Executive Nurse Directors from England and Wales.

METHODS: Participants were purposively sampled and recruited through Chief Nursing Officers and nursing leadership networks. Semi-structured interviews were conducted and recorded online via Teams. Braun and Clarke's approach to thematic reflexive analysis was applied to data analysis.

RESULTS: Executive Nurse Directors played a critical role during the COVID-19 pandemic. Six themes are explored: tensions, and adaptive response to personal leadership styles; uncertainty and …

A Stable Isotope Study To Investigate Water Movement In The Los Lagos Region Of Southern Chile, Kritan Subedi

Civil Engineering ETDs

The Los Lagos region in southern Chile, located in northwest Patagonia, features rain-fed agricultural lands, glacial lakes, forests, farmlands, and volcanic soils. This study investigates water movement within a micro-basin using stable isotope analysis and hydrological modeling over eight weeks. It aims to develop a conceptual model of water movement by elucidating interactions between precipitation, soil water, and streamflow. Findings highlight the critical role of deeper soil layers in sustaining streamflow during dry spells and indicate that soil acts as a buffer, maintaining hydrological continuity despite variable precipitation. Improved understanding of these dynamics can inform watershed management and water resource …

A New Approach To Counting Fossil And Modern Pollen Grains:: The Orderly Count, Tutku Tuncalı Yaman, Bikem Ekberzade, Hülya Caner, Ruya Y. Dagdeviren, Sena Inkaya, Nurgul K. Kılıc, Suzanne A.G. Leroy, Fabienne Marret, Cetin Senkul, Jessie Woodbridge, Meral Avci

School of Geography, Earth and Environmental Sciences

Palynology, the study of pollen and spores, plays a crucial role in various scientific disciplines, including earth sciences (paleovegetation and paleoclimatology), botany, allergy, archaeology, forensic sciencs and cosmetics. This study delves into the critical question in fossil pollen analysis studies: the minimum count of pollen grains required for accurate estimation of vegetation composition. Various statistical methods have been proposed over the years to address this question. Our research introduces an alternative technique, the orderly count, tailored to the nature of palynological analysis. We apply this method to diverse sediment catchments, including peat bogs, marine and lake sediments, from different geographical …

Virtue Appreciation And Sustainability In Olafur Eliasson’S Ice Watch, Nicole Hall

Contemporary Aesthetics (Journal Archive)

This paper is a case study of Olafur Eliasson’s Paris installation of Ice Watch (2014-2018) that coincided with the Climate Change COP-21 conference at the United Nations in 2015, and whose message was poignantly felt as a reminder of global warming, the melting polar regions, and the current environmental crisis. In particular, I explore how and what might we learn from this installation, to consider and rethink the relationship between aesthetic value, ethical value, and the concept of sustainability. Considering that Eliasson’s work requires relational perceptual-intellectual double awareness, it is argued that virtuous appreciation, judgment, and evaluation emerge if engaged …

Toward Concurrent Identification Of Human Activities With A Single Unifying Neural Network Classification: First Step, Andrew Smith, Musa Azeem, Chrisogonas O. Odhiambo, Pamela J. Wright Phd, Ms, Med, Rn, Cen, Hanim E. Diktas, Spencer Upton, Corby K. Martin, Brett Froeliger, Cynthia F. Corbett, Homayoun Valafar

Publications

The characterization of human behavior in real-world contexts is critical for developing a comprehensive model of human health. Recent technological advancements have enabled wearables and sensors to passively and unobtrusively record and presumably quantify human behavior. Better understanding human activities in unobtrusive and passive ways is an indispensable tool in understanding the relationship between behavioral determinants of health and diseases. Adult individuals (N = 60) emulated the behaviors of smoking, exercising, eating, and medication (pill) taking in a laboratory setting while equipped with smartwatches that captured accelerometer data. The collected data underwent expert annotation and was used to train a …

Recovering Landscape And Landscape Beauty In Environmental Aesthetics, Paolo Furia

Contemporary Aesthetics (Journal Archive)

In this article, I will pin down some elements to recover the concept of landscape in the context of environmental aesthetics. Such insertion of landscape in environmental aesthetics entails the questioning of the dualism between nature and culture that still lays at the basis of much literature in environmental aesthetics. My argument will unfold in three steps: first, I will show how the original question of environmental aesthetics, as elaborated by Ronald Hepburn in 1966, presupposes a distinction between nature and culture rooted in the moral contempt for excessive modernization and urbanization. Second, I will criticize some theories, not all …

Landscape Education, Enskilment, And Aesthetics: Complex Skills For Our Time, Alberto L. Siani

Contemporary Aesthetics (Journal Archive)

Environmental education is undoubtedly a pressing need in our time. Landscape education may be seen as something more restricted in scope and necessity, and more disengaged. However, as I will first argue, because of the intrinsically concrete, localized, aesthetic character of landscapes in their difference from environment, landscape education in fact can also be seen as a more complex and challenging concept that can be framed in terms of enskilment. Second, to better clarify this concept and highlight the theoretical and practical difficulties related to it, this paper will then turn to some Wittgensteinian ideas about learning, especially his concept …

No Trace, No Waste? The Art Of Living In Trashscapes, Mădălina Diaconu

Contemporary Aesthetics (Journal Archive)

Humans have always striven to overcome their finitude by leaving traces. The phenomenology and hermeneutics of the twentieth century interpreted traces as meaningful sources for reconstructing the past and disregarded their materiality. This culturalist and retrospective approach nowadays has become untenable, as it is impossible to generate significative traces without producing waste as well. Waste itself forms a special category of trace that is unintentional and partly nocuous. Moreover, a final repository appears to have perversely fulfilled the dream of leaving ineffaceable traces that would survive humanity itself. In this new context, a future-oriented approach, one that would engage collectivities …

Embracing Social-Emotional Learning And Nurturing Character: A Systematic Review Of Intersectional-Eq Strategies For Educational Leaders, Leticia G. Candelaria-Archuleta

Teacher Education, Educational Leadership & Policy ETDs

The COVID-19 pandemic expanded education beyond traditional academics, highlighting the importance of social-emotional learning (SEL) and character education (CE) for positive youth outcomes. This study examined the role of educational leadership in implementing SEL and CE in schools through a term coined Intersectional-EQ. This study centered on a cutting-edge approach using grey literature, specifically doctoral dissertations, to capture current trends in unprecedented times. A systematic review through Covidence, guided by PRISMA and PICO frameworks, was conducted. Findings highlight the impact of leadership on SEL and CE through an intersectional lens. Future work is aimed to support holistic student growth by …

Revisionary Taxonomy Within The Acmaeoderini, Joel Dubois

LSU Master's Theses

The jewel beetles (Coleoptera: Buprestidae) are the 8th largest family of beetles and fill various important ecological roles including decomposers, pollinators, and leaf miners. The cosmopolitan buprestid tribe Acmaeoderini is extremely diverse, with more than 700 species across 14 genera. Historically, the acmaederines from Afro-Eurasia have received thorough morphological treatment and nearly all species from these areas have been separated into various genus and subgenus groupings. Contrastingly, past studies in the Americas have been mostly restricted to alpha-level taxonomic descriptions, and only a very small percentage of species are placed into any formal group. The aim of this study was …

Set-Based Tests For Genetic Association Studies With Interval-Censored Competing Risks Outcomes, Zhichao Xu, Jaihee Choi, Ryan Sun

Faculty, Staff and Student Publications

Over the past decade, massive genetic compendiums such as the UK Biobank have gathered extensive genetic and phenotypic data that hold the potential to provide unparalleled insight into the genetic etiologies of various complex diseases. However, much of the disease information is collected as time-to-event outcomes in interval-censored form, and conventional tools for genetic association analysis are often not available for this type of data. For example, set-based inference for common and rare variants analysis is a fundamental investigation in germline genetics studies, but there is a lack of approaches that can perform set-based testing when the interval-censored outcome of …

Can Vocabulary And Grammar Hold The Doorway For College Reading Success? The Case Of Arabic Learners Of English, Zainab A. Allaith

International Journal for Research in Education

Reading is an important skill for college success. This study investigated cognitive predictors of English reading comprehension success among college students whose first language is Arabic. Knowledge of vocabulary/grammar emerged as the strongest predictor of reading success, followed by silent reading fluency, and then decoding skill. However, metacognitive awareness of reading strategies did not statistically significantly contribute to the model. Findings suggest that Arabic speakers draw on their vocabulary and grammar knowledge when tackling an English reading comprehension task, skills that are language specific to L2. Implications include the recommendation for placing the development of college students’ language reservoir at …

Do We Meet Their Needs? Honors Students’ Perspectives And Experiences Of Honors Programs, Saad M. Alamer

International Journal for Research in Education

This qualitative study investigates university students’ perceptions and experiences in the honors program at King Saud University (KSU). A total of twenty gifted university students were interviewed. The findings indicate that the honors program was perceived to be mediocre in content, and students found it to lack challenge and appeal. The participants experienced a lack of engagement with the program at the university compared to the pre-university programs they had experienced in their school years. Students reaffirmed that they benefited more from interactions with others in the program than from their interactions with staff and members of other programs. This …

Effects Of Running Shoe Stack Height On Movement Variability - A Shared Biomechanical And Motor Control Perspective, Bernd J. Stetter, Cagla Fadillioglu, Stefan Sell, Thorsten Stein

ISBS Proceedings Archive

Understanding how shoe features affect motor control processes is crucial for designing targeted running shoes. The purpose of this study was to investigate adaptations of coupled movement components, i.e. kinematic synergies (kSYNs), when running with different shoe stack heights (19 mm, 35 mm, and 50 mm). The applied analysis combined a principal component analysis, support vector machine classifiers, and stride-to-stride variability (SSV) calculations. The results showed classification rates ranging from 82.9% to 94.4% across different stack heights. Notably, only the 50 mm stack height demonstrated increased SSV for the kSYNs that highly contribute to separating the two stack heights when …