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Comparative Analysis Of Outcomes In Adult Spinal Deformity Patients With Proximal Junctional Kyphosis Or Failure Initially Fused To Upper Versus Lower Thoracic Spine, Oluwatobi O Onafowokan, Munish Chandra Gupta, Et Al.

2020-Current year OA Pubs

No abstract provided.

Schedulability Analysis Of Multi-Phase Limited-Preemption Tasks, Benjamin Standaert

McKelvey School of Engineering Graduate Student Theses & Dissertations

This work addresses hard real-time systems, in which tasks must be scheduled so that they are guaranteed to meet deadlines. In particular, when tasks execute across multiple domains with high preemption costs, the combined cost of these preemptions can cause the system to become unschedulable. The number of preemptions must therefore be bounded to limit the overall task execution time, while ensuring that task blocking times are small enough to allow the system to be schedulable. Prior work introduces the Multi-Phase Secure model, which describes a more exact version of this scenario, and an algorithm to determine schedulability of sporadic …

Safety And Optimality Monitors For Learning-Enabled Systems Using Conformal Prediction, Jackson Cox

McKelvey School of Engineering Graduate Student Theses & Dissertations

The use of machine learning to create data-driven plant models and controllers has led to an increased need for safety and optimality monitors for model-based systems. System plant models are subject to uncertainty due to learning constraints such as unseen data and overfitting or physical constraints such as unknown dynamics and noise. This uncertainty is detrimental to safety-critical systems and must be properly regulated. To curb this uncertainty, we create prediction sets using the guarantees provided by Conformal Prediction. With a user-specified high probability, these prediction sets contain the true plant system states for an entire prediction horizon, which we …

Characterization Of An Inorganic Powder-Based Scintillation Detector Under A Uhdr Electron Beam, Daline Tho, Sam Beddar

Faculty, Staff and Student Publications

Background: Ultra-high dose rate (UHDR) radiation therapy needs a reliable dosimetry solution and scintillation detectors are promising candidates. In this study, we characterized an inorganic powder-based scintillation detector under a 9 MeV UHDR electron beam.

Methods: A mixture of ZnS:Ag powder and optic glue was coupled to an 8 m Eska GH-4001-P polymethyl methacrylate (PMMA) optical fiber. We evaluated the dependence of the detector on dose per pulse (DPP), pulse repetition frequency (PRF), and pulse width (PW). Additionally, we determined the stability and the reproducibility of the detector.

Results: The signal ratio between the PMMA clear optical fiber and the …

Comparison Of Vendor-Pretrained And Custom-Trained Deep Learning Segmentation Models For Head-And-Neck, Breast, And Prostate Cancers, Xinru Chen, Yao Zhao, Hana Baroudi, Mohammad D El Basha, Aji Daniel, Skylar S Gay, Cenji Yu, He Wang, Jack Phan, Seungtaek L Choi, Chelain R Goodman, Xiaodong Zhang, Joshua S Niedzielski, Sanjay S Shete, Laurence E Court, Zhongxing Liao, Fredrik Löfman, Peter A Balter, Jinzhong Yang

Faculty, Staff and Student Publications

Background/objectives: We assessed the influence of local patients and clinical characteristics on the performance of commercial deep learning (DL) segmentation models for head-and-neck (HN), breast, and prostate cancers.

Methods: Clinical computed tomography (CT) scans and clinically approved contours of 210 patients (53 HN, 49 left breast, 55 right breast, and 53 prostate cancer) were used to train and validate segmentation models integrated within a vendor-supplied DL training toolkit and to assess the performance of both vendor-pretrained and custom-trained models. Four custom models (HN, left breast, right breast, and prostate) were trained and validated with 30 (training)/5 (validation) HN, 34/5 left …

Characterization Of An Inorganic Powder-Based Scintillation Detector Under A Uhdr Electron Beam, Daline Tho, Sam Beddar

Faculty, Staff and Student Publications

(1) Background: Ultra-high dose rate (UHDR) radiation therapy needs a reliable dosimetry solution and scintillation detectors are promising candidates. In this study, we characterized an inorganic powder-based scintillation detector under a 9 MeV UHDR electron beam. (2) Methods: A mixture of ZnS:Ag powder and optic glue was coupled to an 8 m Eska GH-4001-P polymethyl methacrylate (PMMA) optical fiber. We evaluated the dependence of the detector on dose per pulse (DPP), pulse repetition frequency (PRF), and pulse width (PW). Additionally, we determined the stability and the reproducibility of the detector. (3) Results: The signal ratio between the PMMA clear optical …

Transcriptomic Clustering Of Chronic Lymphocytic Leukemia: Molecular Subtypes Based On Bruton’S Tyrosine Kinase Expression Levels, Gorkem Kismali, Ganiraju Manyam, Nitin Jain, Cristina Ivan, Betty Lamothe, Mary L Ayres, Lakesla R Iles, William G Wierda, Varsha Gandhi

Faculty, Staff and Student Publications

Historically, CLL prognostication relied on disease burden, reflected in clinical stage. Later, chromosome abnormalities and genomics suggested several CLL subtypes which were aligned with response to therapy. Gene expression profiling data identified pathways associated with CLL progression. We hypothesized that transcriptome and proteome may identify functional omics associated with CLL nosology. As a test cohort, we utilized publicly available treatment-naïve CLL transcriptomics data (n = 130) and did consensus clustering that identified BTK-expression-based clusters. The BTK-High and BTK-Low clusters were validated in public and our in-house databases (n = >550 CLL patients). To associate with functional relevance, we took samples …

Invasion Stress Mitigates Climate Stress In A Brackish Marsh Amphipod, Lorna E. Haworth, Sarah Nancollas, Susie N. Landa, Anne E. Todgham, Richelle L. Tanner

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

1. Organisms in coastal brackish ecosystems face not only highly variable environmental conditions, but the intensity and stochasticity of these environmental conditions are anticipated to increase due to climate change. While environmental changes are often presented unilaterally as stressors, there are some anthropogenic environmental transformations, such as the introduction of habitat forming plant species, that may mitigate physiological stress imposed by warming. In Suisun Marsh in the California Delta, native plant canopies allow light and heat to penetrate to the understory yet the canopies of the introduced Phragmites australis reed block out sunlight and heat for organisms living below.
2. We set …

Influenza Knowledge And Barriers To Vaccination In Immunosuppressed Patients In The Pediatric Rheumatology Clinic., Julia G. Harris, Leslie Favier, Jordan T. Jones, Maria Ibarra, Michael J. Holland, Emily Fox, Kelly Jensen, Ashley K. Sherman, Ashley M. Cooper

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Most patients with a pediatric rheumatic disease are at increased risk of influenza due to immunosuppressive medication use. Despite initial quality improvement efforts, our influenza vaccination rate plateaued at 72%, which prompted a survey of patients and families to assess provider vaccine recommendations, influenza knowledge, and barriers to influenza vaccination.

METHODS: Patients on immunosuppressive medication or their parent were eligible to complete a survey between July 2019 and January 2020. Survey questions assessed demographics, rheumatology diagnosis, immunosuppressive medication(s), influenza vaccination recommendation, patient/parent influenza knowledge, and barriers to influenza vaccination. Influenza vaccination rates for immunosuppressed patients were acquired each influenza …

Autoethnographic Examination Of Moral Distress While Working For The For-Profit Substance Use Disorder Treatment Sector, Kapil Nayar

Walden Dissertations and Doctoral Studies

Interpersonal conflicts and moral distress due to authority figures' unethical and illegal practices are widely discussed topics in the literature. Coping with these experiences and becoming a whistleblower, however are understudied in the counseling field, and are often stigmatized yet advocated for in our codes of ethics. The purpose of this qualitative autoethnographic study is to (1) show moral distress exists in the for-profit sector of substance use disorder treatment; (2) moral distress results from counselors discovering evidence of unethical and illegal activities; (3) moral distress results from the act of blowing the whistle and (4) offers a roadmap for …

Reducing Attrition In Medication-Assisted Treatment: Strategies From Behavioral Health Leaders, Tony Shaw

Walden Dissertations and Doctoral Studies

This qualitative case study explores strategies to reduce attrition rates in medication-assisted treatment programs, drawing on the perspectives of behavioral health leaders and guided by the principles of the Baldridge Excellent Framework. It aims to implement effective strategies to enhance client retention and improve treatment outcomes. Drawing from 18 years of professional experience in behavioral health, this research analyzes current practices and identifies interventions to improve program effectiveness. Data collection includes case studies, surveys, and interviews with behavioral health leaders, providing a comprehensive view of the challenges and opportunities within these programs. The study revealed several key factors affecting retention …

The Psychological And Physical Impact Of The Opioid Crisis On Families, Adrienne Antoinette Hunter Wells Green

Walden Dissertations and Doctoral Studies

Many rural areas in the United States have experienced an opioid crisis. Social support programs could be created to address social support for the families affected by opioid addiction. The purpose of this non-experimental, cross-sectional research study was to examine the possible relationship between (a) prescription or non-prescription addiction; (b) opioid addiction or another addiction; (c) the amount of family social support of a family member who has ongoing interactions with the individual struggling with addiction; and (d) stress of the family member in a rural area. Bowen’s family systems theory provided the theoretical framework for the study. A non-probability …

Gene Expression Regulation By Au-Rich Elements And Au-Rich Element Binding Proteins, Courtney Fay Jungers

Arts & Sciences Graduate Student Theses and Dissertations

The regulation of messenger RNA (mRNA) splicing, stability, and translation efficiency are major modes for controlling gene expression – which is essential for life. RNA-binding proteins (RBPs) and microRNAs (miRNAs) are trans-acting factors that bind to cis-elements influencing the stability and translation of the mRNA transcript. AU-rich elements (AREs) are cis-elements that are targeted by AU-rich element binding proteins (ARE-BPs). Here, I show a novel role for AREs and AU-rich element binding protein 1 (AUF1) during alternative splicing and report on interactions of RBPs and miRNAs to design a new treatment for breast cancer by interrupting these interactions in the …

A Filter-Based Model Of Visual Recognition, Olivia Rose Bockler

Arts & Sciences Graduate Student Theses and Dissertations

Visual recognition, a key perceptual process, enables primates to identify faces, food, tools, and potential threats in their environment. Cortical neurons along the ventral visual stream—spanning from early visual cortex (V1) through inferotemporal cortex (IT), with long-range projections to ventrolateral prefrontal cortex (vlPFC)—are essential for visual recognition. Traditional models propose that neuronal representations increase in complexity in each stage of this pathway, culminating in object-specific representations in higher-order cortex. However, this hypothesis remains debated, particularly as artificial visual models have countered that individual neurons along this pathway may function more as filters contributing to distributed representations of objects. Thus, this …

Sensitivity And Application Of Frequency Domain High-Density Diffuse Optical Tomography (Fd Hd-Dot), Weihao Fan

Arts & Sciences Graduate Student Theses and Dissertations

Functional near-infrared spectroscopy (fNIRS) is a non-invasive imaging technique that measures hemodynamic responses in the brain, similar to functional magnetic resonance imaging (fMRI) but with distinct advantages. By utilizing near-infrared light, fNIRS can penetrate biological tissues and detect changes in oxygenated and deoxygenated hemoglobin. Additionally, fNIRS is portable, noninvasive and inexpensive. Within the realm of fNIRS, several measurement techniques exist, including Continuous Wave (CW), Frequency Domain (FD), and Time Domain (TD) methods. In this dissertation, we focused on the effects, fundamental principles and applications of FD designs. We provided the introduction in Chapter 1, and discussed the background theory and …

Recollective Features In The Natural Language Used To Justify Memory Decisions, Xinran Zhang, Ian G. Dobbins

Arts & Sciences Graduate Student Theses and Dissertations

The natural language people use to justify memory decisions predicts recognition accuracy, in part, because it conveys recollection. This study compared a traditional bag-of-words (BOW) classifier to one using BERT embeddings, and newly tests whether classifier recognition scores also predict the later recall of individual recognition probes. During both training and testing, the BERT classifier outperformed the BOW classifier. Nonetheless, a BOW approach was important for explaining the BERT classifier, accounting for a sizeable portion of its variance and confirming that the BERT classifier was also recollection sensitive. The BERT classifier’s recognition scores predicted future recall and mediated the tendency …

Enhanced Lsmc For Valuation Of Options, Amr Mekawy

Theses and Dissertations

In the world of finance, whether you are a hedger or a speculator, a risk-adverse or a risk-advocate, the use of financial instruments and derivatives will remain pertinent to providing new opportunities for mitigating risks as well as generating profit. Among these instruments are Options, which regardless of their complexity, can be an extremely versatile tool to be utilized across a wide range of different markets.

An option is a derivative that gives the holder the right, but not the obligation to buy or sell the underlying asset either before or at the maturity date of the contract. There are …

An Adaptive Algorithm To Provide Fan Speed Control, Chejung Liu, Vic Chia

Defensive Publications Series

Proposed herein is a new algorithm to facilitate fan speed control (FSC) for cooling fans of electronic devices that utilizes existing sensor readings for a device to determine the altitude at which the device is operating. With this estimated altitude value, fan speed control mechanisms can be enhanced from conventional two-dimensional (2D) control techniques that only consider temperature versus (vs) duty cycle to three-dimensional (3D) control techniques that consider temperature vs altitude vs duty cycle to manage fan speed. Utilizing techniques as proposed herein, an optimized fan speed control mechanism can be provided for electronic devices that reduces power consumption …

Evaluation Of The Presence Of Sarcocystis Spp. In Dogs Raised In Alpaca Farm Enterprises In Cajamarca, Peru, Milena Ydrogo, María Cabrera, Jennifer L. Cuzcano-Anarcaya, Luis A. Vargas-Rocha, Teófilo Torrel

The Thai Journal of Veterinary Medicine

The apicomplexans of the genus Sarcocystis are parasites that infect various animal species, including humans. Both dogs and other carnivores can act as definitive hosts of this protozoan. The present study aimed to determine the frequency of Sarcocystis spp. in domestic dogs raised in three alpaca breeding areas in Cajamarca. Random fecal samples were collected from 102 dogs of different ages and both sexes in three locations related to alpaca breeding: Atahualpa Jerusalén Agricultural Workers Cooperative - Cajamarca (N = 35), SAIS Huacraruco - San Juan (N = 33), and Alpacas Project - Foncreagro - Sorochuco (N = 34). The …

The Four Domains Model Of Artificial Intelligence In Surgical Education: Adapting Applications To Trainee Level, Anant R. Tewari, Jasraj Raghuwanshi, Lawal A. Labaran, Xudong Li

Journal of Innovation in Health Sciences Education

Since the inception of modern medicine, surgical trainees have benefitted from coaching and feedback from senior surgeons. In the high-demand operating room environment, granular feedback is often limited by time constraints. Artificial intelligence (AI) represents a novel frontier in surgical education in that it may be able to provide reliable, objective, and comprehensive feedback in an automated manner. While prior studies have given broad overviews of AI in surgical training, there has been no study to our knowledge that has codified the myriad applications and offered guidance for which applications best suit trainees at various levels of surgical education. We …

Leveraging Gamification And Social Media To Teach Heart Failure Clinical Practice Guidelines In Entry-Level Physical Therapist Education, Kaelee Brockway

Journal of Innovation in Health Sciences Education

Introduction: Clinical practice guideline adherence remains a challenge in health care, with reported rates as low as 26%. Research shows multiple barriers to adherence, including limited access and guideline complexity. Integrating guidelines into education is crucial, demanding innovative methods to enhance translation into practice.

Methods: This multiple methods study explored application of the substitution, augmentation, modification, and redefinition model to integrate social media and gamification activities to engage students in learning action statements of a clinical practice guideline for the management of heart failure. Performance on exam items relevant to the guideline content were used to determine if this …

Setting The Stage For Success: Teaching Behavior Expectations During The First Week, Katie Hamilton, Jamie Nichols

Georgia Association for Positive Behavior Support Conference

A strong start is key to a successful school year, and teaching specific behavior expectations early on helps set the tone for a positive, productive learning environment. This presentation will guide PBIS teams, both new and seasoned, through a proven approach to launching the school year with teaching clear and consistent school-wide behavior expectations. Participants will receive a comprehensive toolkit, including a detailed schedule for the first days of school, customizable presentations for teachers to use in their classrooms, and engaging behavior expectation assignments with answer keys. By implementing these strategies, schools can create a cohesive culture of respect and …

Building Evidence-Based Pbs For Schools, Clinics And Communities, Tom Clees

Georgia Association for Positive Behavior Support Conference

Abstract

For students in both the general and adapted curriculum, low achievement, behavioral excesses and social skills deficits are predictive of each other (Gresham, 2016;). Too, an escalating cycle may lead to further antisocial responses, a decrease in learning outcomes, and exclusion from services for some (Kauffman, 2018). Related to these challenges, the successful application of positive behavior supports has been widely reported by schools, clinics, and community-based services. Although definitions of PBS, and the scope of these practices, vary depending on the reference point of those responsible for administration and application, there seems to be agreement that PBS practices …

The Private Cause Of Action Under Maine's Unfair Trade Practices Act, Steven A. Shaw

Maine Law Review

In 1970 the Maine Legislature passed the Unfair Trade Practices Act (UTPA) which declared unlawful any "unfair methods of competition and unfair or deceptive acts or practices in the conduct of any trade or commerce . . . ." UTPA-type statutes, now common to all states, offer several advantages. The statutes provide for a statutory award of attorneys' fees, create a private cause of action which is simple in comparison to analogous common law claims, and offer a flexible concept of unlawful conduct which many courts have shown a willingness to interpret broadly and sympathetically. Although Maine's UTPA was originally …

Hospital Accountability In Health Care Delivery, C. Elisabeth Belmont

Maine Law Review

In recent years, the role of community hospitals in health care delivery has undergone a dramatic change. Until the latter half of the twentieth century, a hospital was merely a "doctor's workshop," providing physicians with the physical facilities, equipment, and personnel necessary to treat their private patients. Due to progressive medical technology, today's hospital has moved from a passive role in patient care to more active participation in the delivery of total health care. The hospital has become a health care provider in its own right, furnishing a broad range of diagnostic and outpatient services, home care assistance, and specialized …

In Defense Of Civil Juries, Peter W. Culley

Maine Law Review

Criticism of the civil jury system is nothing new. In fact, virtually since its inception the civil jury has been embroiled in controversy. Typically critics argue that: the jury cannot handle the complex or technical case; there is great expense and delay attendant to trial by jury; jury adjudication is of low quality; verdicts rendered by different juries in cases involving similar facts often appear inconsistent. Recently, Justice Donald Alexander of the Maine Superior Court stated that "[t]he civil jury system has outlived its usefulness." In support of his basic premise that the civil jury system is merely an historical …

Deinstitutionalizing The Mentally Retarded In Maine: The Inevitable Face-Off With Zoning, Pamela D. Albee

Maine Law Review

In July 1978, agencies and officials of the State of Maine entered into a federal consent judgment which terminated a class action lawsuit that had dragged on for three years. The consent judgment in Wuori v. Zitnay detailed a comprehensive plan designed to bring about speedy and meaningful relief to the plaintiff class: mentally retarded citizens of Maine involuntarily confined to Pineland Center, Maine's principal institution for the mentally retarded, and certain others who were conditionally released from Pineland and in community placements. The relief granted was a right to be provided the least restrictive and most normal living conditions …

The Decline Of The Privity Rule In The Maine Law Of Tort Products Liability: A Conceptual History, Dennis M. Patterson

Maine Law Review

No single issue has more preoccupied modern jurisprudential writers than the limitations of precedent on the lawmaking power of judges. Yet despite this singular concentration, no scholarly consensus has emerged regarding what those limitations are or what form they should take. This continuing theoretical dispute recently manifested itself in a series of decisions rendered by the Law Court. Last spring in the case of Adams v. Buffalo Forge Co., the Law Court reconsidered a significant aspect of two decisions of the previous term: Burke v. Hamilton Beach Division and Hurd v. Hurd. In Burke and Hurd the court decided that …

Comeau V. Maine Coastal Services: The Quantum Theory And The Rescue Doctrine In Workers' Compensation, George F. Eaton Ii

Maine Law Review

Section 51 of the Maine Workers' Compensation Act provides that in order to be compensable, an employee's injury must arise out of and occur in the course of the employment. The decision of the Maine Supreme Judicial Court in Comeau v. Maine Coastal Services upheld the Workers' Compensation Commission's denial of the plaintiff's petition for an award of compensation. In reaching its decision, however, the Law Court departed from the long-settled analytical approach of treating the "arising out of" and the "in the course of" requirements as separate criteria both of which must be met in order to establish a …

The Vitality Of The Doctrine Of Punitive Damages In Maine, Kevin F. Gordon

Maine Law Review

On four separate occasions between December 1981 and February 1982, the Maine Supreme Judicial Court called into question the continued vitality of the common law doctrine of punitive damages. The substantive propriety of punitive damages was not challenged by any of the defendants in those four cases. As a result, the Law Court assumed for the purposes of each opinion that punitive damages could be awarded by a court "in some instances without explicit statutory authorization." Nevertheless, in a footnote to Braley v. Berkshire Mutual Insurance Co., the court challenged this assumption. Noting that the doctrine of punitive damages initially …