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Effect Of Paxlovid On Neurodevelopmental Disorder Diagnosis Outcomes In Offspring Of Mothers Infected With Sars-Cov-2 During Pregnancy, Simone Rogers Jan 2025

Effect Of Paxlovid On Neurodevelopmental Disorder Diagnosis Outcomes In Offspring Of Mothers Infected With Sars-Cov-2 During Pregnancy, Simone Rogers

CMC Senior Theses

The onset of the 2020 COVID-19 pandemic brought concern over the effects that this virus would have on pregnancy and fetal outcomes, specifically neurodevelopmental outcomes. Maternal immune activation (MIA), caused by infection during pregnancy, is known to result in neurodevelopmental disorder (NDD) diagnosis in offspring, typically autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). This effect has already been observed in mothers who were infected with COVID-19 during pregnancy. However, in 2023, Paxlovid, the COVID-19 antiviral drug, became available to patients experiencing symptoms of the virus, including pregnant women. Consequently, this study seeks to determine whether the risk of …


Addressing Chronic Stress: Activating The Healing Responses, Lily Walther Jan 2025

Addressing Chronic Stress: Activating The Healing Responses, Lily Walther

CMC Senior Theses

This paper seeks to explore the negative effects of chronic stress on the body, emphasize the tissue, cellular, and genetic healing responses that exist to combat these effects, and illustrate the behavioral and physiological interventions that can activate these responses. The concepts of stress and chronic stress have been explained through a progression of models that have been updated over the decades. This includes early theories such as The General Adaptation Syndrome and the Homeostatic Model, as well as more recent depictions such as the Reactive Scope Model. The healing responses are explored on a variety of levels to illustrate …


Ubiquitin, Cavitand, And Nmr: 15n-1h Hsqc Analysis Of Cavitand Binding Domains On Ubiquitin, Grant Stucky Jan 2025

Ubiquitin, Cavitand, And Nmr: 15n-1h Hsqc Analysis Of Cavitand Binding Domains On Ubiquitin, Grant Stucky

CMC Senior Theses

Ubiquitin and its derivatives through side chain modification are present in many of the degradation pathways for proteins found in neurodegenerative diseases. A non-toxic method for determining the amount of these proteins could have biosensing applications, but the binding domains of such proteins are not well characterized. 15N-1H HSQC analysis of ubiquitin’s interactions with different concentrations of a small negatively charged host molecule called cavitand provides insight into the binding interactions with side chains on the protein such as lysine and arginine. This is done comparing the HSQC spectra of different concentrations of cavitand and ubiquitin to …


The Garden Of Pdyn: The Impact Of Pdyn Gene Deletion On Ethanol Self-Administration And Reinforcement In Female Mice, Catherine Ruan Jan 2025

The Garden Of Pdyn: The Impact Of Pdyn Gene Deletion On Ethanol Self-Administration And Reinforcement In Female Mice, Catherine Ruan

CMC Senior Theses

Debilitating over-consumption of alcohol, often culminating into a prevalent psychiatric disorder known as alcohol use disorder (AUD), stands as one of the United States’ most expensive societal battles to face (Harwood et al., 1998). Consequently, the public’s desire and scientists’ motivation to develop novel pharmacological solutions to treat it is high. Recent and ongoing research presents new insights into the role of the dynorphin/kappa opioid receptor (DYN/KOR) system as an inhibitor of dopamine release and a regulator of the negative affective states that come with alcohol withdrawal (Karkhanis et al., 2017). However, this growing body of literature is predominantly conducted …


The Predictors Of Self-Censorship On College Campuses, Henry I. Long Jan 2025

The Predictors Of Self-Censorship On College Campuses, Henry I. Long

CMC Senior Theses

Across U.S. colleges, speech climates are poor. Self-censorship and discomfort expressing views are common. At the same time, we find wide variation in speech climates across different institutions. This study is the first to identify factors that predict variation in speech climates. Drawing on data from multiple sources, including a survey of 58,807 undergraduates across 257 colleges and universities from the Foundation from Individual Rights and Expression (FIRE), this study constructs a first-of-its-kind dataset to test three core theories of self-censorship found in the literature—student-centric theories, faculty-centric theories, and administrator-centric theories. We find moderate evidence to support each theory. Overall, …


A Bad Bet For Adolescents: Psychological Perspectives On Sports Betting & Digital Gambling Technologies, Kaitlyn Helfrich Jan 2025

A Bad Bet For Adolescents: Psychological Perspectives On Sports Betting & Digital Gambling Technologies, Kaitlyn Helfrich

CMC Senior Theses

Digital sports betting is a rapidly expanding sector of the gambling industry, allowing users to place wagers on the outcomes of sporting events from virtually anywhere. While structurally comparable to traditional gambling systems, sports betting is often perceived as a more socially acceptable and accessible alternative, contributing to its growing appeal and largely positive sentiment among Americans. Yet, in the seven years since sports betting has become legalized, growing numbers of Americans have reported psychological and financial problems stemming from problem gambling. Of particular concern is the increasing percentage of adolescents engaging with these platforms, despite legal restrictions on underage …


Forecasting Equity Betas Using Option-Implied Moments, Ivan Kolesnikov Jan 2025

Forecasting Equity Betas Using Option-Implied Moments, Ivan Kolesnikov

CMC Senior Theses

Traditional beta estimates are constructed from historical stock‑and‑market returns and therefore adjust only as fast as realized data accrue. This thesis investigates whether the forward‑looking information embedded in equity‑option prices can enhance beta forecasts. Using near‑end‑of‑day quotes for 236 S&P 500 firms between 2007 and 2024, I extract risk‑neutral variance and skewness, construct five alternative beta estimators (historical, option‑implied, and three hybrids), and evaluate them against realized betas over six‑, twelve‑, and twenty‑four‑month windows. Rolling‑OLS beta remains the most accurate benchmark at short horizons, yet option‑implied moments add economically and statistically significant value when systematic exposure is expected to change …


Procedural Reform And One-Sided Litigation: Evaluating The Impact Of California’S Fair Debt Buying Practices Act, Kaitlyn Seever Jan 2025

Procedural Reform And One-Sided Litigation: Evaluating The Impact Of California’S Fair Debt Buying Practices Act, Kaitlyn Seever

CMC Senior Theses

This study evaluates whether California’s Fair Debt Buying Practices Act (CFDBPA), effective January 2014, improved litigation outcomes in consumer debt lawsuits. The CFDBPA sought to curb abusive practices by imposing heightened documentation requirements on debt buyers. Using a dataset of 535,766 limited-jurisdiction debt collection cases filed in Los Angeles County between 2012 and 2022, a constrained difference-in-differences event study design compares outcomes between secondary and non-secondary debt buyers before and after the law’s implementation.

The analysis finds modest changes: dismissals for secondary buyers increased slightly relative to non-secondary buyers, but default judgment rates remained high. Defendant response rates declined for …


You Lose, You Lag: Evidence From 2020 And 2024 On U.S. Partisan Bias, Presidential Election Defeat, And Perceived Future Real Income, Brandon O. Felix Jan 2025

You Lose, You Lag: Evidence From 2020 And 2024 On U.S. Partisan Bias, Presidential Election Defeat, And Perceived Future Real Income, Brandon O. Felix

CMC Senior Theses

Recent presidential elections, in particular the two most recent ones, have revealed striking partisan divides, not only in political attitudes but also in household economic expectations. This study investigates how partisan electoral loss shapes perceived changes in real income across income groups, using data from the University of Michigan Survey of Consumers surrounding the 2020 and 2024 U.S. presidential elections. I employ ordered logistic regression models for the baseline models and generalized ordered logistic regression models for those models with pertinent demographic controls in order to analyze the probability of respondents expecting real income losses, stability, or gains, respectively. Generating …


Cmc Thesis Chatbot, Luis Gomez Jan 2025

Cmc Thesis Chatbot, Luis Gomez

CMC Senior Theses

This GitHub repo is a senior thesis for Claremont McKenna College; it is a thesis about theses. The project is an interactive RAG-based chatbot that helps students, researchers, and faculty explore Claremont McKenna College senior theses. The goal was to create a domain-specific chatbot to show that it is possible to combat the limitations of AI, including hallucinations, outdated data, and lack of domain expertise. The website link is:

CMCThesisChatbot


Analyzing Political Sentiment On Micro-Blogging Data: A Lexicon And Machine Learning Approach To The 2024 U.S. Presidential Election, Ava Grey Jan 2025

Analyzing Political Sentiment On Micro-Blogging Data: A Lexicon And Machine Learning Approach To The 2024 U.S. Presidential Election, Ava Grey

CMC Senior Theses

This paper explores the trends in sentiment towards U.S. presidential candidates Kamala Harris and Donald Trump through micro-blogging social media text during the five months leading up to the election. Two datasets of varying sizes and origins were used to contextualize and validate analysis findings. The analyses include both a lexicon-based approach and a machine learning predictive method. Common sentiment analysis techniques like term frequency, term frequency inverse, various lexicons, and n-grams were utilized during the lexicon approach. During the modeling, a random forest was utilized in addition to the methods used during the lexicon approach. Results showed that overall …


Predictive Policing In Practice: A Case Study Of Chicago's Strategic Subject List, Stella Cheng Jan 2025

Predictive Policing In Practice: A Case Study Of Chicago's Strategic Subject List, Stella Cheng

CMC Senior Theses

Technological advancements in big data and algorithmic modeling have contributed to the rise of advanced predictive policing techniques. Law enforcement agencies utilize these tools to predict and prevent crime before it occurs. However, these techniques have been the subject of extensive ethical debates, particularly regarding their potential to reinforce racial biases. This thesis provides a historical overview and analysis of a prominent example of people-based predictive policing: the Chicago Police Department’s Strategic Subject List (SSL) program. The SSL program revolved around an algorithm designed to predict individuals' risk of involvement in a shooting, using indicators such as co-arrest networks, age, …


Skilled Immigrant Labor And Ai Innovation: A Longitudinal Panel Analysis Of H-1b Sponsorship Effects On Ai Patenting, Xinyue Zhang Jan 2025

Skilled Immigrant Labor And Ai Innovation: A Longitudinal Panel Analysis Of H-1b Sponsorship Effects On Ai Patenting, Xinyue Zhang

CMC Senior Theses

This thesis examines how firm-level access to high-skilled immigrant labor, measured through H-1B visa petitions and approvals, affects innovation in artificial intelligence (AI). Using a panel dataset linking firm-year H-1B filings from the U.S. Citizenship and Immigration Services (USCIS) Employer Data Hub to AI patent records from the United States Patent and Trademark Office (USPTO) between 2009 and 2019, the analysis estimates fixed effects regressions predicting AI patenting activity. The results show that H-1B approvals are positively and significantly associated with future AI patent counts, while petitions alone are not. Alternative specifications using inverse hyperbolic sine transformations and changes in …


The Pricing Of Forecast-Based Earnings Uncertainty In Equity Markets, Brenda G. Galvan Jan 2025

The Pricing Of Forecast-Based Earnings Uncertainty In Equity Markets, Brenda G. Galvan

CMC Senior Theses

This paper constructs a firm-level measure of earnings forecast uncertainty by adapting the macroeconomic methodology of Jurado et al. (2015) to micro-level financial statement data from Compustat and CRSP. Using a two-stage estimation procedure, I first forecast the scaled year-over-year changes in earnings, defined as the change in income before extraordinary items normalized by firm sales,based on lagged firm fundamentals. I then model the squared forecast errors to extract the unpredictable component of earnings variation, generating a forward-looking, firm-specific measure of ex-ante uncertainty. Empirically, I examine whether this forecast uncertainty measure is priced in equity markets by regressing future stock …


Optimal Capital Allocation Decisions And Investments In The Nba, Anderson Cynkar Jan 2025

Optimal Capital Allocation Decisions And Investments In The Nba, Anderson Cynkar

CMC Senior Theses

This thesis investigates the relationship between salary concentration and winning in the NBA, primarily focusing on how the concentration of payroll among top-earning players influences success. Several concentration metrics were constructed and employed including the use of a Herfindahl-Hirschman Index (HHI) to measure the share of payroll each player receives across a team. I used fixed effects regressions and clustered standard errors at a team level to control for unobserved factors that remain the same over time. The results revealed a consistent inverted U-shape curve, signaling that an optimal concentration of capital exists for the highest paid player, two highest …


Beyond The Bank Account: Financial Inclusion And Maharashtra's Microenterprises, Kyra F. Variyava Jan 2025

Beyond The Bank Account: Financial Inclusion And Maharashtra's Microenterprises, Kyra F. Variyava

CMC Senior Theses

Financial inclusion has evolved from mere bank account ownership to a broader imperative that encourages the active and consistent use of financial services to cultivate practices of savings and better financial management. Focusing on the underserved communities of Maharashtra’s microenterprise sector, this thesis evaluates the effectiveness of four central financial inclusion schemes: Pradhan Mantri MUDRA Yojana, Credit Guarantee Fund Trust for Micro and Small Enterprises, Stand-Up India, and Pradhan Mantri Street Vendor’s AtmaNirbhar Nidhi. This thesis develops a four-dimensional evaluative framework, assessing each scheme’s performance in accessibility, awareness and financial literacy efforts, adoption of digital services, and accountability and oversight …


Neural Correlates Of Attentional Biases In Dietary Choice: Role Of Childhood Socioeconomic Status, Justine Jamie N. Gotico Jan 2025

Neural Correlates Of Attentional Biases In Dietary Choice: Role Of Childhood Socioeconomic Status, Justine Jamie N. Gotico

CMC Senior Theses

Childhood poverty has been shown to increase adult risk for obesity above and beyond its direct effects on adult socioeconomic status (SES). One proposed mechanism of these effects is by shifting behavioral patterns of dietary consumption and choice, for example by increasing rapid attention to high-calorie unhealthy foods. Yet, whether such neural mechanisms can explain observed differences in dietary behavior based on childhood SES remains an open question. Here we used event-related potentials (ERPs) to examine early attentional correlates of low childhood SES during a dietary choice task, based on research suggesting that early attentional biases toward high-calorie foods emerge …


The Paradox Of Pleasure: How Sex-Positive Feminism Constrains Female Freedom, Katherine S. Lanzalotto Jan 2025

The Paradox Of Pleasure: How Sex-Positive Feminism Constrains Female Freedom, Katherine S. Lanzalotto

CMC Senior Theses

This thesis critiques popular sex-positive narratives that espouse sex as the path to female liberation and empowerment despite ideological and material constraints that tailor female sexual expression to male desires. It interrogates sex-positive feminism's evolution and impact on female freedom. Despite its progressive intentions, mainstream sex-positive discourse has paradoxically constrained female freedom. This thesis analyzes how sex positivity inhibited female freedom, developing a nuanced framework of negative, positive, and republican freedom. This framework elucidates new constraints introduced by pro-sex thinking, such as compulsory female sexuality, the commodification of women under capitalism, and intersectional oversights in sex-positive thinking that particularly affect …


Optimizing Bitcoin Allocation: Predictability Of Bitcoin Portfolio Weights Through Macroeconomic Variables, Kirby Baynes Jan 2025

Optimizing Bitcoin Allocation: Predictability Of Bitcoin Portfolio Weights Through Macroeconomic Variables, Kirby Baynes

CMC Senior Theses

This thesis examines whether Bitcoin is a beneficial asset in a diversified, mean-variance optimized portfolio and whether its portfolio weights can be reliably predicted using macroeconomic variables. Using data from December 2013 to February 2025, the analysis applies rolling-window portfolio optimization and OLS regressions with Newey-West standard errors to test the relationship between Bitcoin allocations and a set of macroeconomic indicators. Results show that Bitcoin receives non-zero weights across portfolios and that its optimal allocation is sensitive to variables such as changes in the Credit Spread and Yield Curve. These variables were statistically significant in several models and produced meaningful …


The Counter-Cyclicality Of Earnings Management: Evidence Through 2024, William J. Hall Jan 2025

The Counter-Cyclicality Of Earnings Management: Evidence Through 2024, William J. Hall

CMC Senior Theses

This thesis examines the relationship between macroeconomic conditions and earnings management, extending the analysis of Hillegeist and Lin (2019) using updated data through 2024. Based on 16,635 firm-quarter observations, my study affirms the results found in prior literature and confirms that there is a negative association between the change in GDP and the direction of firms’ earnings management behavior, indicating that earnings management is counter-cyclical. My study also finds that firms manage earnings asymmetrically based on the current macroeconomic state, with firms managing earnings more in economic downturns and less in expansions. My findings suggest that despite major macroeconomic and …


Nfl Moneyline Market Efficiency: Predictability Of Odds Movements And The Overvaluation Of Home-Field Advantage, Elijah Costa Jan 2025

Nfl Moneyline Market Efficiency: Predictability Of Odds Movements And The Overvaluation Of Home-Field Advantage, Elijah Costa

CMC Senior Theses

This thesis evaluates the degree to which the NFL moneyline market - one of the highest volume sports betting markets - aligns with weak-form market efficiency by analyzing high-frequency odds data from the 2020 to 2024 seasons. This study discovers significant predictability in the direction that odds will shift throughout the week leading up to kickoff, as a result of the sportsbooks’ adjustments to sharp action, rather than injury news. Furthermore, this study discovers that the market has overvalued the home field advantage in forecasted close games, leading to a profitable system by betting on away teams in games with …


Preserving Roots: Assessing The Assyrian Community In Iraq Through The Eyes Of Aid Workers, Tara E. Dawood Jan 2025

Preserving Roots: Assessing The Assyrian Community In Iraq Through The Eyes Of Aid Workers, Tara E. Dawood

CMC Senior Theses

This study aims to assess the unique challenges and experiences of Assyrians from Iraq from the perspective of humanitarian aid workers. The research questions are as follows: what factors contribute to Christians choosing to leave Iraq, especially in the last 25 years?; what actions by the Iraqi government would deter them from leaving or support them in returning? This study is significant because it focuses attention on the excessive numbers of Assyrians leaving Iraq. Although they are a minority, their translocation produced a massive resettlement of migrants—more than any other group in Iraq. By analyzing the role of the Iraqi …


Scaling Social Impact Bonds In The United States: Barriers, Incentives, And Policy Solutions, Angelique M. Rivanis Jan 2025

Scaling Social Impact Bonds In The United States: Barriers, Incentives, And Policy Solutions, Angelique M. Rivanis

CMC Senior Theses

Social Impact Bonds (SIBs) are a form of outcomes-based financing that fund social programs by shifting financial risk from the government to private investors. While SIBs have gained international traction, their long-term viability in the United States depends on structural reforms. This thesis examines two completed U.S. SIB projects, Rikers Island in New York and the Just-in-Reach project in Los Angeles, through an analysis of their design, implementation, and outcomes. While both projects focus on criminal justice, they provide context about the scalability of SIBs across multiple social policy areas.The three primary constraints are high transaction costs, limited investor interest, …


Robert Frost And The Myth Of Adam And Eve, Theo Johnson Jan 2025

Robert Frost And The Myth Of Adam And Eve, Theo Johnson

CMC Senior Theses

What exactly it is about the story of Adam and Eve that fascinated Robert Frost is hard to say. Of course, he is not the first to engage with it in writing – for much of recorded human history, the Genesis account of man’s creation has held a place of unparalleled importance in our understanding of what it is to be human, provoking innumerable exegetic responses. In popular literature, too, it has served as inspiration for some of the most celebrated English and American poems. From the “bloodless myth” of Geoffrey Hill’s “Genesis” to the great theodicy of John Milton’s …


Money Matters: Investigating The Emotional, Cognitive, And Biological Pathways Connecting Maternal Early Life Financial Insecurity And Parenting Quality, Elise Power, Stacey N. Doan Jan 2025

Money Matters: Investigating The Emotional, Cognitive, And Biological Pathways Connecting Maternal Early Life Financial Insecurity And Parenting Quality, Elise Power, Stacey N. Doan

CMC Senior Theses

Early life adversity has been shown to have a variety of negative effects on adult functioning, including parenting quality, with implications for child wellbeing. Adverse early life experiences including poverty have been linked to long-term disruptions in emotional, cognitive, and physiological functioning that compromise the ability to provide sensitive, nurturing care. The present study investigated whether emotional regulation difficulties, physiological regulation, and cognitive function mediate the relationship between early life financial insecurity and parenting quality. A sample of 132 mother-child dyads completed self-report measures, biological samples, and cognitive assessments. A multiple mediation model ran in SPSS, revealed a significant indirect …


Alliance In Flux: Oil And The Us-Saudi Strategic Bargain Reconsidered, Austin Andersen Jan 2025

Alliance In Flux: Oil And The Us-Saudi Strategic Bargain Reconsidered, Austin Andersen

CMC Senior Theses

This thesis examines the historical development and future trajectory of the longstanding relationship between the United States and the Kingdom of Saudi Arabia. It traces its roots back to the early twentieth century, during which the Kingdom was established officially and the United States was on the hunt for a substance that quickly became one of the world’s most precious commodities–oil. Since then, oil has both acted as a binding force and a point of contention between the two nations. However, through ups and downs in the partnership, oil has remained at the heart of the arrangement. This study follows …


Exploring Neurodiversity & The Role Of Flexible Workplaces For Organizational Neuroinclusion, Miranda Chen Jan 2025

Exploring Neurodiversity & The Role Of Flexible Workplaces For Organizational Neuroinclusion, Miranda Chen

CMC Senior Theses

This thesis conducted a thorough literature review on the experiences and outcomes of neurodiverse individuals in the workplace and found consistently lower outcomes in well-being, work performance, intention to leave, and job satisfaction compared to neurotypical workers. It examined how the emergence of remote work presents new opportunities for mitigating some workplace challenges around stress and sensory overload, while recognizing that remote work alone falls short as being a definitive solution for the unique challenges faced by neurodiverse people. Instead, it argued for Flexible Work Arrangements (FWA’s) as a comprehensive and systemic strategy to address individual needs and organizational inclusion, …


The Meditative Mind In Sync: The Effects Of Meditative Interpersonal Synchrony On Self-Other Merging, Self-Representation, And Social Connection., Nathan Verba Jan 2025

The Meditative Mind In Sync: The Effects Of Meditative Interpersonal Synchrony On Self-Other Merging, Self-Representation, And Social Connection., Nathan Verba

CMC Senior Theses

This study investigates the effects of meditative interpersonal synchrony, operationalized through OM group chanting meditation (OM-GCM), on self-other merging, self-referential thinking, and the quality of social interactions between strangers. Interpersonal synchrony and meditation have been widely studied as distinct phenomena; however, this thesis is the first to examine the potential amplifying effects of their combination. This thesis hypothesized that OM-GCM would lead to higher conversation quality, increased self-other merging, and reduced self-referential thinking compared to a non-meditative synchronous control: humming. To test this, twenty-eight college students, paired into dyads of strangers, engaged in either the OM-GCM or humming condition, followed …


Artificial Intelligence Should Get To Play Games Too: Large Language Models Playing Picobot And Generative Artificial Intelligence As A Teaching Assistant, Jonathan J. Wise Jan 2025

Artificial Intelligence Should Get To Play Games Too: Large Language Models Playing Picobot And Generative Artificial Intelligence As A Teaching Assistant, Jonathan J. Wise

CMC Senior Theses

This thesis identifies strengths and weaknesses of Large Language Models

(LLMs) in a game-based, academic computer science setting. Specifically, it builds a

platform for LLMs to compete on a foundational assignment for entry-level Computer

Science students: playing the game of Picobot. To enable the analysis, it reconstructs

an earlier Picobot simulation: translating from Python2 to Python3, and introducing an

LLM mode that interacts with the Application Program Interfaces (APIs) of multiple

classes of LLMs.

We find that, while the LLM models understand the existence of the Picobot

game, the LLMs require specific instructions to generate valid moves. Therefore, this

thesis …


Donald Trump's Digital Media Campaign: How Podcasts Shaped The Political Views Of Young Men, Natalie Teare Jan 2025

Donald Trump's Digital Media Campaign: How Podcasts Shaped The Political Views Of Young Men, Natalie Teare

CMC Senior Theses

This paper investigates the increase in Donald Trump’s young male voters in the 2024 presidential election through his digital media campaign. Trump was a guest on over 15 podcasts and livestreams, almost exclusively hosted by men. This paper examines three podcasts to discover what techniques Trump used to appeal to male voters: Impaulsive with Logan Paul, This Past Weekend with Theo Von, and The Joe Rogan Experience. The demographic of young men has specific interests, fears, and challenges that affect the strategies politicians use to garner their support. The advents of social media and podcasting have allowed young …