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Synthesis, Characterization, And Biological Activity Of Ni(Ii) And Co(Iii) Thiosemicarbazone Complexes As Potential Anticancer Agents, Jack Martin Jan 2025

Synthesis, Characterization, And Biological Activity Of Ni(Ii) And Co(Iii) Thiosemicarbazone Complexes As Potential Anticancer Agents, Jack Martin

Pitzer Senior Theses

The mechanics by which Reactive Oxygen Species work is an area of great interest given ROS’s wide range of biological applications. From cell signaling and mitochondrial regulation to pathogenesis and tumor cell death, varying concentrations of ROS in a system can lead to a whole host of positive and negative effects. In a similar vein, thiosemicarbazones are known to be equally useful for their myriad of antibacterial, antifungal, antiviral, and antitumoral effects. They have been at the core of the pharmaceutical world or the better part of the last century. The purpose of this work is to synthesize, characterize and …


Verification Of Real-Time Smoke Simulations: A Case Study On Early Summer North American Wildfire Events, Daniel Bonilla Jan 2025

Verification Of Real-Time Smoke Simulations: A Case Study On Early Summer North American Wildfire Events, Daniel Bonilla

Pitzer Senior Theses

As wildfire intensity and frequency escalate in times of unprecedented climate change and severe droughts, it is important to enhance forecasting models that accurately and efficiently predict wildfire smoke movement. NOAA’s experimental Rapid-Refresh Forecasting System with Smoke and Dust (RRFS-SD) aims to improve upon the High-Resolution Rapid Refresh- Smoke (HRRR-Smoke), by extending the domain to include all of North America and incorporating new developments in physics and wildfire parameterizations. Our work explores the process of adding satellite Aerosol Optical Depth (AOD) data, through AERONET, as an additional method of verification of the RRFS-SD experimental model. Using a case study on …


The Arts And Student Engagement: Correlational Insights For School Accountability Of Low Income, English Learners, And Foster Youth, Paul Treesuwan Jan 2025

The Arts And Student Engagement: Correlational Insights For School Accountability Of Low Income, English Learners, And Foster Youth, Paul Treesuwan

CGU Theses & Dissertations

This quantitative study examined the relationship between students’ engagement in the arts and their engagement in both academic classes and the broader school community within a diverse, urban, public charter high school. Using survey data from 251 students in grades 9–12, analyses explored whether arts engagement was associated with academic and school-community engagement and whether these relationships differed across English Learner (EL), low-income (F/R), and foster-youth subgroups. Results revealed that arts engagement was moderately and positively correlated with both academic engagement and school-community engagement confirming consistent cross-domain associations. ANOVA analyses detected no statistically significant differences in engagement levels by EL, …


Achieving Public Goals Using Private Tools: Build-Operate-Transfer Projects In Southeast Asia, Angela J. Niederberger Jan 2025

Achieving Public Goals Using Private Tools: Build-Operate-Transfer Projects In Southeast Asia, Angela J. Niederberger

Scripps Senior Theses

This thesis investigates the infrastructural challenges impeding economic development in Southeast Asia, with a particular focus on the energy and transportation sectors. It examines how Build-Operate-Transfer (BOT) models, a form of Public-Private Partnerships (PPP), have emerged as viable mechanisms to address the region’s persistent infrastructure deficits. Drawing from six case studies across Laos, Vietnam, and Indonesia—including successful and unsuccessful BOT initiatives—this research evaluates the financial, political, and administrative constraints that affect project outcomes. It further explores the role of institutional frameworks, international organizations, and legal reforms in enhancing BOT performance and mitigating risks such as corruption, capacity gaps, and public …


Essays On The Effectiveness Of Diversion Programs In The United States Criminal Justice System, Tairy Ayon Jan 2025

Essays On The Effectiveness Of Diversion Programs In The United States Criminal Justice System, Tairy Ayon

CGU Theses & Dissertations

The United States criminal justice system is at a transformative time, with growing public support for reforms that prioritize rehabilitation over punishment. In response to this shift, prosecutor-led diversion programs are being introduced in areas where they were previously absent and expanded with increased resources in regions already established across the United States. This dissertation measures the effectiveness of these programs in three ways and uses data from six diverse U.S. jurisdictions. In the first chapter, I focus on how age-based eligibility criteria shape participation in diversion programs and its effectiveness in reducing recidivism. To do this, I examine data …


Paths To Mathematics Success: A Path Analysis Of Educational Expenditures To Math Outcomes Of Latine Students, Aldo Ramirez Jan 2025

Paths To Mathematics Success: A Path Analysis Of Educational Expenditures To Math Outcomes Of Latine Students, Aldo Ramirez

CGU Theses & Dissertations

This quantitative critical study employed multiple linear path analysis models with difference scores to investigate the effects of funding adjustments on mathematics learning rates for Latine students. The theoretical framework integrated the Education Production Function with the QuantCrit frameworks to untangle the complex web of relationships associating educational funding adjustments and the academic outcomes of Latine students. The study specifically examined these relationships across U.S. districts stratified by poverty level (20%). To strengthen the causal inference and enhance control over confounding variables, the research design incorporated several key methodological features: (1) the use of difference scores to control for baseline …


Petroleum Reservoir Dynamics, Mehdi Zeidouni Jan 2025

Petroleum Reservoir Dynamics, Mehdi Zeidouni

E-Textbooks

The book is structured into nine chapters, each designed to build a comprehensive understanding of reservoir engineering principles. Chapter 1 introduces the discipline and its connections with other areas of petroleum engineering. Chapters 2 through 5 address steady-state flow and its various complexities: Darcy’s equation and its limitations (Chapter 2); flow geometries and skin factor concepts (Chapter 3); compressible oil and gas flow (Chapter 4); and non-horizontal flow using the flow potential concept (Chapter 5).

In Chapter 6, the pressure diffusivity equation is explored alongside key concepts of radius of investigation and average reservoir pressure. Chapter 7 delves into the …


How Theories Of Art Can Inform Debates About Ai, Jessica Silbey Jan 2025

How Theories Of Art Can Inform Debates About Ai, Jessica Silbey

Emory Law Journal

Debates about artificial intelligence (AI) tend to swing between the optimistic and the apocalyptic. I propose a less binary approach that frames conversations about AI from the perspectives of theories of art and creativity. Whether we agree that AI is artificial or intelligent, whether it should be constrained or liberated, we cannot deny its influence on literary, artistic, and innovative production. AI may be described as simply a new tool to produce art and science, like the camera or the microscope, or it may transform and reshape art and science, the way the internet transformed global communication. Either way, these …


Electrical Engineering, Physics Jan 2025

Electrical Engineering, Physics

Program Revisions/Additions

No abstract provided.


Satellite Based Crop Yield Predictor, Muhammad Hadi, Moeen Haider, Muddasir Rizwan, Ahmed Raza, Hassan Atiq Jan 2025

Satellite Based Crop Yield Predictor, Muhammad Hadi, Moeen Haider, Muddasir Rizwan, Ahmed Raza, Hassan Atiq

BSCS Final Year Projects

This project presents a satellite-based crop yield prediction system tailored for Pakistan’s key crops. Leveraging multi-source satellite imagery from Landsat and Sentinel-2 combined with historical provincial yield data from AMIS, the system predicts crop yields using a custom convolutional neural network (CNN). The model incorporates feature engineering, data preprocessing, and hyperparameter tuning to improve accuracy. Experimental results demonstrate promising predictive performance with an error rate as low as 10.35%. This work addresses agricultural productivity challenges by enabling data-driven decision making for policymakers and stakeholders.


Evaluation Of Corticosteroid Use In Pediatric Patients With Bronchiolitis, Kaitlyn Margraf Pharmd Jan 2025

Evaluation Of Corticosteroid Use In Pediatric Patients With Bronchiolitis, Kaitlyn Margraf Pharmd

Pharmacy Residency

Presented at Midyear Clinical Meeting.

Nearly 67% of pediatric patients treated for bronchiolitis received steroids with no underlying indication, which deviates from clinical guidelines. Patients who received steroids without an indication had an apparent trend toward more oxygen support and had an increase in maximum flow rate compared to patients with an indication for steroid use.


True Threats And The Neuroscience Of Fear, Paul E. Mcgreal Jan 2025

True Threats And The Neuroscience Of Fear, Paul E. Mcgreal

Case Western Reserve Law Review

No abstract provided.


Waive Goodbye To Corporate Accountability? Reforming The Federal Arbitration Act To Protect Consumers With Small-Value Claims, Matthew Matolka Jan 2025

Waive Goodbye To Corporate Accountability? Reforming The Federal Arbitration Act To Protect Consumers With Small-Value Claims, Matthew Matolka

Case Western Reserve Law Review

No abstract provided.


Abortion On The Ballot: How Direct Democracy Shapes Abortion Policy Post-Dobbs, Serena E. Klebba Jan 2025

Abortion On The Ballot: How Direct Democracy Shapes Abortion Policy Post-Dobbs, Serena E. Klebba

Honors Theses

Since the return of abortion policy to the states following Dobbs v. Jackson Women’s Health Organization (2022), sixteen states have considered ballot measures addressing core questions of abortion access. Distinct from pre-2022 initiatives, these recent measures present binary choices on issues such as viability-based access, six-week bans, and the existence or repudiation of a right to abortion in state constitutions. Although existing scholarship generally frames initiatives and referendums as mechanisms that enhance congruence between public opinion and policy outcomes, this focus overlooks the broader effects of direct democratic processes on voters. I hypothesize that there is something unique in the …


The Anatomy Of A Reconstruction: From Fourier Space To Image Recovery In Computed Tomography, Charlotte P. Maurer Jan 2025

The Anatomy Of A Reconstruction: From Fourier Space To Image Recovery In Computed Tomography, Charlotte P. Maurer

Honors Theses

This thesis develops the mathematical foundations of computed tomography (CT) reconstruction through the lens of harmonic analysis. Beginning with the Schwartz class, we introduce the Fourier transform and its role in expressing the Radon transform and its inversion via a fractional Laplacian. After constructing the Radon transform in general dimension R^d, we specialize to the cases d = 2 and d = 3, demonstrating explicit inversion formulas and the associated instability in lower dimensions. For its computational advantages, we study filtered back-projection using classical low-pass filters (Ram-Lak, Shepp–Logan, Cosine, Gaussian) and formulate a discrete reconstruction algorithm grounded in …


Predicting Human Steering From Optic Flow Using Deep Convolutional Neural Networks, Katie E. Bernard Jan 2025

Predicting Human Steering From Optic Flow Using Deep Convolutional Neural Networks, Katie E. Bernard

Honors Theses

Human driving is a complex visuomotor task and the specific visual clues that guide it remain under investigation. While prior research has emphasized gaze-based strategies such as the Tangent Point and Future Path hypotheses, recent evidence highlights the potential role of optic flow, the visual motion pattern perceived during self-movement, as critical to steering ability. This thesis explores whether raw optic flow alone can support accurate predictions of human steering behavior. We trained a convolutional neural network to map optic flow vector fields to steering angles in a virtual reality driving simulation. The dataset, collected by Giguere et al., included …


Microbial Degradation Of Kelp-Derived Dissolved Organic Matter In The Context Of Carbon Sequestration, Sophia N. Riazi-Sekowski Jan 2025

Microbial Degradation Of Kelp-Derived Dissolved Organic Matter In The Context Of Carbon Sequestration, Sophia N. Riazi-Sekowski

Honors Theses

Kelp, or brown algae, is an emerging form of ocean-based biological carbon dioxide removal, converting dissolved CO2 into organic molecules via photosynthesis. The export of detritus and dissolved organic carbon (DOC) from coastal beds to beyond the continental shelf contributes to carbon sequestration, especially through the microbial production of refractory DOC (RDOC). The influence of microbial degradation on kelp-derived DOC is not yet well understood, contributing to inconsistency in carbon sequestration estimates. This study utilizes dark bottle incubations of both blades and holdfasts from two farmed kelp species in the Gulf of Maine — Saccharina latissima and Saccharina angustissima — …


Optimizing Radial Interfaces For Eye-Movement Authentication On Smartphones, Trey V. Tuscai Jan 2025

Optimizing Radial Interfaces For Eye-Movement Authentication On Smartphones, Trey V. Tuscai

Honors Theses

Radial authentication interfaces offer privacy-preserving, calibration-free eye-movement authentication. While their effectiveness has been demonstrated on large displays, their performance on smartphones remains underexplored. This study investigates seven radial interface configurations on the iPhone 13, varying the number of radial indicators and password lengths to examine trade-offs between accuracy, security, and entry time. Through a controlled eye-tracking experiment with 27 participants, we evaluate each configuration’s performance and collect user prioritizations of the three factors. Our findings reveal that shorter passwords with fewer indicators improve speed and accuracy but reduce security, while longer configurations enhance security at the cost of usability. Based …


Drivers Of Heat Pump Installation In Maine: Climate Shocks, Politics, And Incentives, Micah J. Margolis Jan 2025

Drivers Of Heat Pump Installation In Maine: Climate Shocks, Politics, And Incentives, Micah J. Margolis

Honors Theses

Heat pumps are a growing trend as climate adaptation measures around the world and are gaining significant popularity and attention due to a number of environmental and social factors across Maine. Homeowners in Maine face difficult financial and personal pressures when considering a heat pump. Impacting this decision is a high cost of energy, a substantial rebate offsetting the purchase price, as well as summers and winters that are warming beyond record highs and lows. Previous research has looked at specific populations or large regions without considering the long-term personal drivers of this decision. I use data from Efficiency Maine, …


Tracing The Lines In Comics And Life: Genealogies And My Place Within Them, Audrey M. Loo Jan 2025

Tracing The Lines In Comics And Life: Genealogies And My Place Within Them, Audrey M. Loo

Honors Theses

My thesis is a hybrid English Lit/Creative Writing project on comics. The English Lit half is an Artist’s Statement comprised of scholarly research and both analytical and personal writing, and this work will necessarily inform and be informed by the Creative Writing half, in which I create my own comics.


Does The 25th Amendment Merit Reform?: The Challenge Of Determining Presidential Disability, Karena R. Andreassen Jan 2025

Does The 25th Amendment Merit Reform?: The Challenge Of Determining Presidential Disability, Karena R. Andreassen

Honors Theses

This research project examines the persistent lack of use of the 25th Amendment to the United States Constitution in its original form, despite many calls for the reform of the language or expansion of its application as situations unfold. Adopted in 1967, the amendment was created to address the challenges of presidential succession and incapacity. However, historical events over the last few decades, such as the assassination attempt on Ronald Reagan, Reagan’s colon cancer, and the general increase in the age at which presidents assume office, have contributed to scrutiny over the amendments’ provisions. This study will explore why specifically …


Why Community: The Potentials And Limitations Of Community Engagement In Restorative Justice, Emily P. Chauhan Jan 2025

Why Community: The Potentials And Limitations Of Community Engagement In Restorative Justice, Emily P. Chauhan

Honors Theses

This thesis explores the role of community in restorative justice through both the criminologist and practitioner perspectives. Through investigating the limitations of the U.S. penal system, which ranks highest globally in incarceration rates yet fails to ensure public safety, the research investigates restorative justice as a victim-cantered, harm-driven alternative. It emphasizes how restorative justice redefines crime by focusing on healing and accountability rather than punishment of the criminals/harm-doers. This thesis examines how communities are essential to restorative processes and how restorative justice, in turn, helps to build communities. Drawing from case studies, models, and interviews this thesis questions the assumptions …


Understanding Perspectives Of Autism Spectrum Disorder In Central Maine, Bridget B. Meehan Jan 2025

Understanding Perspectives Of Autism Spectrum Disorder In Central Maine, Bridget B. Meehan

Honors Theses

The present study investigates perspectives of Autism Spectrum Disorder (ASD) in Rural Central Maine and the support measures needed to optimize students’ inclusive education experiences. The research examines views of three primary stakeholders: parents/guardians, teachers (general education and special education), and clinicians. By utilizing Bronfenbrenner’s Ecological Systems Model, I explore the complexity of inclusive education by analyzing how macrosystem beliefs (operationalized through logics) and mesosystem interactions across microsystems influence the educational experience for students with ASD (Bronfenbrenner, 1979). Part one of the research consists of a systematic literature review for each stakeholder, incorporating 45 sources across three prominent education databases. …


Shouting Down Democracy: The Role Of The Deeply Engaged In American Political Discourse, Annaliese Fleck Jan 2025

Shouting Down Democracy: The Role Of The Deeply Engaged In American Political Discourse, Annaliese Fleck

Honors Theses

In an age of heightened polarization and increasing incivility in politics, a small but influential subset of Americans, known as the deeply engaged have emerged as dominant voices in political dialogue. This thesis investigates who these individuals are, what drives them, and how their behavior impacts democratic participation in the United States. Through a combination of theoretical analysis and original survey data, this study constructs a profile of the deeply engaged and distinguishes them from the general electorate. Drawing on foundational concepts of free speech, including isegoria and parrhesia, and the philosophies of John Stuart Mill and Karl Popper, this …


From Living With The Land To Vacation Timeshares: The Impact Of Outdoor Recreation On The United States’S Recognition Of Shoshone, Timpanogos, And Havasupai Ancestral Homelands, Harry T. Robison Jan 2025

From Living With The Land To Vacation Timeshares: The Impact Of Outdoor Recreation On The United States’S Recognition Of Shoshone, Timpanogos, And Havasupai Ancestral Homelands, Harry T. Robison

Honors Theses

The romantic view of the Western United States from the perspective of a US resident is fueled by the thought of adventure and expansion. The phenomena of the "Wild West," frontier ideology, and manifest destiny have kindled a love of being outside and pursuing new and "unexplored" territory. Long before those ideologies came into play, people already inhabited these landscapes. As colonists moved West, many of those inhabitants were forcefully moved onto reservations. Those people include the Shoshone people of Wyoming, the Timpanogos people of Utah, and the Havasupai people of Arizona. Alongside this history of displacement, the United States …


Introducing Catalizer: A Framework For Prototyping Models Of Biological Systems, Andy M. Day Jan 2025

Introducing Catalizer: A Framework For Prototyping Models Of Biological Systems, Andy M. Day

Honors Theses

Modeling the light response system of Nannochloropsis oceanica brings

a set of challenges that make modeling difficult. Notably, potential models

may contain a large number of chemical species. A large number of

species creates a quadratic explosion in the number of potential pathways.

In addition, mathematically defining these pathways is error prone, yet

follows a surprising simple set of rules. We seek to create a domain specific

language which can precisely define these chemical reaction networks.

Once the networks have been defined, they can be exported as procedures

defined in popular programming languages for further analysis.


Local Limit Theorems On Finitely Generated Abelian Groups, Yutong Yan Jan 2025

Local Limit Theorems On Finitely Generated Abelian Groups, Yutong Yan

Honors Theses

In this thesis, we classify the pointwise behavior of finite-range random walks on finitely generated abelian groups in terms of local limit theorems. Random walks are central objects of research in probability theory, and the theory has found applications in statistics, physics, and even card shuffling. One significant topic in this line of study is random walks on finitely generated groups. Starting from the pioneering work of G. Pólya and H. Kesten, random walks on finitely generated groups have been studied extensively. However, many notable results on the subject (local limit theorems, for example) make assumptions about periodicity and irreducibility …


The Future Of Code Style: Learning With Gamified Online Tools, Jacob C. Tjaden Jan 2025

The Future Of Code Style: Learning With Gamified Online Tools, Jacob C. Tjaden

Honors Theses

High-quality code is universally pursued by software developers, and one of the most effective indicators of code quality is code style. However, code style is difficult to teach, particularly to introductory students and programmers who benefit most. In this project, we aim to investigate how online tools can improve and teach Python code style, as well as identify the role of gamification in the process. We build an online platform called Fishy that combines code style appraisal tools and utilizes gamification concepts. Our platform incorporates educational metrics such as a code analysis score and targeted quizzes to assess user performance. …


Affine Groups: A Functorial Perspective, Vladimir Khabaev Jan 2025

Affine Groups: A Functorial Perspective, Vladimir Khabaev

Honors Theses

A familiar construction associated to any commutative ringRwith1is its group of units, traditionally denoted by Rx= {u in R | uv = 1 for some v in R}. This is but one out of many ways to get a group from a ring. To see at least one other way, we need a mild change in perspective: units may instead be characterized as elements for which the linear transformation f(r) = u ⋅ r is an isomorphism of R as a module over itself. That is to say, Rx = GL(1, R …


From Colony To Classroom: British Rule And Contemporary Educational Outcomes In India, Yashvita Shukla Jan 2025

From Colony To Classroom: British Rule And Contemporary Educational Outcomes In India, Yashvita Shukla

Honors Theses

This study analyzes the modern day legacy of British colonial ruling structures on Indian educational outcomes. In directly ruled areas, the British retained total control, while Indian princes in indirectly ruled areas had administrative agency. I find that directly ruled districts have higher literate population shares across both genders over three census years, but no significant difference by 2011 in primary, secondary, and tertiary education, controlling for colonial geographic conditions. Gender-disaggregated results generally find stronger colonial effects for women than men. This thesis challenges earlier findings and implies that the British effort to create an educated administrative class and their …