Digital Commons Network^™

Processors Log Packet, Ann Hamilton

UNH Cooperative Extension

No abstract provided.

Time To Weight Plateau With Tirzepatide Treatment In The Surmount-1 And Surmount-4 Clinical Trials, Deborah B Horn, Scott Kahan, Rachel L Batterham, Dachuang Cao, Clare J Lee, Madhumita Murphy, Sylvia Gonsahn-Bollie, Farai Chigutsa, Adam Stefanski, Julia P Dunn

Faculty, Staff and Student Publications

The rate of weight reduction during obesity treatment declines over time and eventually reaches a weight plateau. We investigated factors associated with time to weight plateau (TTWP) in tirzepatide-treated participants with obesity or overweight in a post-hoc analysis of SURMOUNT-1 and SURMOUNT-4 trials. Participants adherent to tirzepatide treatment and achieving ≥5% weight loss by primary endpoint (week 72 SURMOUNT-1; week 88 SURMOUNT-4) were included. Weight plateau was defined as a weight change < 5% over a 12-week interval and all subsequent 12-week intervals. TTWP was time from randomization to the start of the first 12-week interval. Association between baseline characteristics and TTWP was assessed. Overall, 1438 participants in SURMOUNT-1 and 259 in SURMOUNT-4 were included. Across BMI categories (overweight, class I, II, and III), median TTWP in SURMOUNT-1 was 24.3, 26.0, 36.1, and 36.1 weeks, respectively (p < .05, class II and III vs. overweight). By week 72, 90.2%, 88.9%, 87.6%, and 87.8% of participants in SURMOUNT-1 had reached a weight plateau across respective BMI categories [Correction added on 22 January 2025, after first online publication: The "72%" has been changed to "72" in this version.]. Higher doses of tirzepatide (10/15 mg), younger age, and female sex were more likely to reach a weight plateau later. Results in SURMOUNT-4 were similar. In this post-hoc analysis, most participants reached a weight plateau by week 72. Higher doses of tirzepatide, younger age, and female sex were associated with a longer TTWP. Further research into modifiers of weight reduction phases with tirzepatide may inform treatment decisions for its use in chronic weight management. Clinical Trial Registration: ClinicalTrials.gov, identifiers NCT04184622 (SURMOUNT-1) and NCT04660643 (SURMOUNT-4), available at http://www.clinicaltrials.gov/.

Expanding The Clinical Spectrum Of Porokeratosis Ptychotropica, Brooke R Bartley, Dylan R Maldonado, Steven Mays, Ronald P Rapini

Faculty, Staff and Student Publications

Porokeratosis ptychotropica (PP) is a rare variant of porokeratosis, typically presenting as pink to brown hyperkeratotic plaques in the gluteal cleft and buttocks, defined histologically by multiple cornoid lamellae. Diagnosis of PP is challenging due to its clinical overlap with other dermatologic conditions and inconsistent terminology in the literature. This case report describes a 47-year-old woman exhibiting clinical and pathological features of PP but with a more diffuse presentation than previously documented. The case emphasizes the diagnostic complexities of PP, particularly in atypical presentations, and highlights the critical role of histological examination in distinguishing it from other porokeratoses.

Assessment Of Contextualized Reinforcement Pathology In A Community Sample Of Young Adult Substance Users, Ángel García-Pérez, Alba González-Roz, Roberto Secades-Villa, Gema Aonso-Diego, Sara Weidberg, Jin H Yoon

Faculty, Staff and Student Publications

Background: Alcohol, tobacco, and cannabis are the most commonly used substances among young populations, often leading to polysubstance use, which correlates with problematic consumption and adverse health outcomes. The contextualized reinforcer pathology (CRP) model explains addictive behaviors through several constructs, including the following: drug demand, delay discounting (DD), and substance-free and substance-related reinforcement. Most previous studies have focused on a single CRP construct and the couse of only two substances. This study aimed to characterize three subgroups of young adults reporting past month use of alcohol only, alcohol + tobacco or cannabis, and alcohol + tobacco + cannabis, in terms …

An Enzyme-Linked Immunosorbent Assay (Elisa)-Based Activity Assay For Amp-Activated Protein Kinase (Ampk), Trezze P Nguyen, Shangze Lyu, Yang Liu

Faculty, Staff and Student Publications

AMP-activated protein kinase (AMPK) is the master regulator of cellular and organismal energy homeostasis, playing an essential role in modulating metabolism and other cellular processes. Substantial efforts have been made to develop pharmacological modulators of AMPK activity due to their therapeutic potential against various diseases. Measuring AMPK activity in vitro is a fundamental step for testing AMPK activators and inhibitors. Here, we report an enzyme-linked immunosorbent assay (ELISA)-based AMPK activity assay with simple steps and high sensitivity. This assay offers a robust, in-house alternative to the traditional radioactive methods and other approaches that rely on specialized reagents or commercial kits.

Pharmacogenetics Of Plasma Dolutegravir Exposure During 1-Month Rifapentine/Isoniazid Treatment Of Latent Tuberculosis, Nia Covington, Anne F Luetkemeyer, Marjorie Z Imperial, Rodney Dawson, Yoninah Cramer, Sue Rosenkranz, Susan Swindells, Irina Gelmanova, Anchalee Avihingsanon, Roberto C Arduino, Wadzanai Samaneka, Kelly E Dooley, Rada Savic, Anthony T Podany, David W Haas

Faculty, Staff and Student Publications

In Advancing Clinical Therapeutics Globally protocol A5372, a pharmacokinetic study of dolutegravir with 1-month of daily rifapentine/isoniazid, twice-daily dolutegravir offset the induction effects of rifapentine on plasma dolutegravir trough concentrations (C trough ). Here, we characterize the impact on dolutegravir C trough of UGT1A1 , AADAC , and NAT2 polymorphisms that affect dolutegravir, rifapentine, and isoniazid, respectively. People with HIV receiving dolutegravir-based antiretroviral therapy with an indication to treat latent tuberculosis underwent pharmacokinetic sampling during dolutegravir 50 mg once daily alone, and on day 28 of dolutegravir 50 mg twice daily with rifapentine/isoniazid. Multivariable linear regression models characterized genetic associations …

Three-Dimensional Printed Models To Accelerate Resident Surgical Learning Curve For Standard Endoscopic Sinus Surgery Techniques, Jumah G Ahmad, Alexander J Citardi, Amber U Luong, William C Yao

Faculty, Staff and Student Publications

Background: Endoscopic sinus surgery presents significant visuospatial challenges to surgical trainees. We tested the utility of novel 3D printed models to simulate sinus surgery tasks to improve endoscopic skillsets in resident trainees.

Methods: This was a prospective quality improvement study of 10 ENT residents (PGY1-5). Participants rotated through 4 stations with different 3D simulation training modules designed to enhance endoscopic skillsets in the axial, sagittal and coronal planes (e.g., straight forceps to grasp a bead from a ledge, angled instruments to cannulate openings). Participants completed a self-assessment survey on the subjective sinus surgical skills using a visual analog …

Endovascular Repair Of Type A Dissection Using Thoracic Stent Graft With Innominate Artery Flaring To Correct For Length Mismatch, Aidin Baghbani-Oskouei, Lucas Ruiter Kanamori, Safa Savadi, Steven Maximus, Thanila A Macedo, Anthony Estrera, Salman A Arain, Gustavo S Oderich

Faculty, Staff and Student Publications

Type A aortic dissection is the most common aortic catastrophe posing challenges for endovascular repair owing to the fragile aortic wall, proximity to the aortic valve, coronaries, and supra-aortic trunks. While open surgical repair remains the gold standard, endovascular repair is considered in select high-risk patients who meet anatomical criteria, including more than 10 mm length between sinotubular junction to primary tear, aortic diameter of less than 40 mm, and suitable length between sinotubular junction and innominate artery. This illustrated video and case presentation address a modified technique using stent graft flaring of the innominate artery to adjust for length …

Corrigendum To “Cardiac Manifestations And Outcomes Of Covid-19 Vaccine-Associated Myocarditis In The Young In The Usa: Longitudinal Results From The Myocarditis After Covid Vaccination (Maciv) Multicenter Study”, Supriya S Jain, Steven A Anderson, Jeremy M Steele, Hunter C Wilson, Juan Carlos Muniz, Jonathan H Soslow, Rebecca S Beroukhim, Victoria Maksymiuk, Xander Jacquemyn, Olivia H Frosch, Brian Fonseca, Ashraf S Harahsheh, Sujatha Buddhe, Ravi C Ashwath, Deepika Thacker, Shiraz A Maskatia, Nilanjana Misra, Jennifer A Su, Saira Siddiqui, Danish Vaiyani, Aswathy K Vaikom-House, M Jay Campbell, Jared Klein, Sihong Huang, Christopher Mathis, Matthew D Cornicelli, Madhu Sharma, Lakshmi Nagaraju, Jocelyn Y Ang, Santosh C Uppu, Preeti Ramachandran, Jyoti K Patel, Frank Han, Jason G Mandell, Jyothsna Akam-Venkata, Michael P Dilorenzo, Michael Brumund, Puneet Bhatla, Parham Eshtehardi, Karina Mehta, Katherine Glover, Matthew L Dove, Khalifah A Aldawsari, Anupam Kumar, Spencer B Barfuss, Adam L Dorfman, Prashant K Minocha, Alexandra B Yonts, Jenna Schauer, Andrew L Cheng, Joshua D Robinson, Zachary Powell, Shubhika Srivastava, Anjali Chelliah, Yamuna Sanil, Lazaro E Hernandez, Lasya Gaur, Michael Antonchak, Marla Johnston, Jonathan D Reich, Narayan Nair, Elizabeth D Drugge, Lars Grosse-Wortmann

Faculty, Staff and Student Publications

This corrects the article "Cardiac manifestations and outcomes of COVID-19 vaccine-associated myocarditis in the young in the USA: longitudinal results from the Myocarditis After COVID Vaccination (MACiV) multicenter study" in volume 76, 102809.

Performance In Multi-Joint Force-Plate Assessments In Male And Female Crossfit® Athletes, James R. Jowsey, G. Gregory Haff, Paul Comfort, Nicholas Joel Ripley

Research outputs 2022 to 2026

Background: CrossFit^® aims to be equitable between both males and female athletes, supporting equal representation and equal prize money at international events. However, to date, limited information is known on CrossFit^® athletes’ performance in the countermovement jump (CMJ), countermovement rebound jump (CMR-J), and isometric mid-thigh pull (IMTP) when assessed using force plates, and if there are any differences between sexes. Therefore, the purpose of the present study was to observe whether any sex-based differences and relationships exist between performance within these assessments. Methods: A total of CrossFit athletes (43 male = 32.8 ± 9.0 years; height 1.78 ± …

International Multidisciplinary Consensus Recommendations On Clinical Application Of Three-Dimensional Visualization In Precision Surgery For Pediatric Liver Tumors, Qian Dong, Wenli Xiu, Benjie Tang, Eiso Hiyama, Mary T Austin, Yeming Wu, Xiaojun Yuan, Chengzhan Zhu, Chengli Liu, Hiroki Ishibashi, Karthik K Tappa, Huanmin Wang, Chuandong Sun, Yuntao Ma, Hongwei Xi, Jian Wang, Jianghua Zhan, Kyong Ihn, Mitsuo Shimada, Mingman Zhang, Mary E Brindle, Patrick B Thomas, Shigehisa Fumino, Tao Liu, Thom Lobe, Udo Rolle, Shan Wang, Xiaowen Zhai, Yoshinori Koga, Yoshiaki Kinoshita, Yuzuo Bai, Zhaozhu Li, Zhe Wen, Weikang Pan, Krysta M Sutyak, Pier C Giulianotti

Faculty, Staff and Student Publications

Background: Pediatric liver tumors are predominantly primary malignant tumors, and complete tumor resection with sufficient preservation of liver tissue is crucial for improving prognosis. However, due to the delicate anatomical structure of the pediatric liver and the relatively large size of the tumors, especially in difficult cases, the surgical challenges are substantial. While precision liver surgery are widely applied in clinical practice, pediatric cases require more customized approaches. The application of three-dimensional (3D) visualization technology is crucial for enhancing surgical accuracy, allowing for precise preoperative planning and intraoperative guidance.

Methods: This consensus was collaboratively developed by 36 experts from eight …

Finger Orthoses For Rehabilitation―Part I: Biomedical Insights And Additive Manufacturing Innovations, Alireza Nouri, Lijing Wang, Hamed Bakhtiari, Yuncang Li, Cuie Wen

Research outputs 2022 to 2026

Background: Finger orthoses are essential for treating injuries, deformities, and disorders of the upper limbs by supporting, immobilizing, or correcting deformities. Recent advances in three-dimensional (3D) printing have significantly enhanced precision and customization compared to traditional fabrication methods such as thermoplastic molding, plaster or fiberglass casting, and the use of prefabricated splints. Methods: The present review was conducted using PubMed, Scopus, and other databases with keywords such as “hand therapy”, “additive manufacturing”, “finger and thumb”, and “orthosis”. Only English-language publications were considered, with a primary focus on articles published between 2010 and 2025. Key themes were identified and categorized into …

Pre-Amplification Of Cell-Free Dna: Balancing Amplification Errors With Enhanced Sensitivity, Wei Yen Chan, Ashleigh Stewart, Russell J. Diefenbach, Elin S. Gray, Jenny H. Lee, Richard A. Scolyer, Georgina V. Long, Helen Rizos

Research outputs 2022 to 2026

Circulating tumour DNA (ctDNA) is a promising biomarker for personalised oncology. However, its clinical utility is limited by detection sensitivity, particularly in early-stage disease. T-Oligo Primed Polymerase Chain Reaction (TOP-PCR) is a commercial amplification approach utilising an efficient “half-adapter” ligation design and a single-primer-based PCR strategy. This study evaluated the clinical value and application of cell-free DNA (cfDNA) pre-amplification. cfDNA amplification with TOP-PCR preserved DNA size profiles and resulted in a 22 bp size increase due to the half-adaptor ligation. Gene target amplification rates varied, showing lower efficiency for the GC-rich TERT promoter amplicon and higher efficiency for the BRAF …

Paradoxical Leadership As Facilitator In The Idea Journey: The Role Of Regulatory Focus, Irene E. De Pater, Shenghui Wang, Ming Yi, Eric F. Rietzschel

Research outputs 2022 to 2026

Drawing upon theory and research on innovation, conservation of resources, and paradoxical leadership, we examine relationships between three stages of the innovative process (i.e., idea generation, idea dissemination, and idea implementation) and the role of paradoxical leadership as a facilitator of the transitions between these stages. In addition, we examine the motivational mechanisms (promotion and prevention focus) that can explain the relevance of paradoxical leadership in the innovative process. Results of a four-wave study show that paradoxical leadership, through employee promotion focus, strengthens the relationship between idea generation and idea dissemination, whereas paradoxical leadership, through employee prevention focus, strengthens the …

Baseline Habitual Dietary Nitrate Intake And Alzheimer's Disease Related Neuroimaging Biomarkers In The Australian Imaging, Biomarkers And Lifestyle Study Of Ageing, Anjana Rajendra, Nicola P. Bondonno, Kevin Murray, Liezhou Zhong, Stephanie R. Rainey-Smith, Samantha L. Gardener, Lauren C. Blekkenhorst, Vincent Doré, Victor L. Villemagne, Simon M. Laws, Belinda M. Brown, Kevin Taddei, Colin L. Masters, Christopher C. Rowe, Ralph N. Martins, Jonathan M. Hodgson, Catherine P. Bondonno

Research outputs 2022 to 2026

Background: Dietary nitrate, as a nitric oxide (NO) precursor, may support brain health and protect against dementia. Objective: Our primary aim was to investigate whether dietary nitrate is associated with neuroimaging markers of brain health linked with Alzheimer's disease (AD). Participants: Study participants were cognitively unimpaired individuals from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing (AIBL) who had β-amyloid positron emission tomography (PET) scans (n = 554) and magnetic resonance imaging (MRI) scans (n = 335) and had completed a Food Frequency Questionnaire at baseline. Methods: Source-specific nitrate intakes were estimated using comprehensive nitrate food composition databases. Rates …

A Predictive Model For The Shear Capacity Of Ultra-High-Performance Concrete Deep Beams Reinforced With Fibers Using A Hybrid Ann-Anfis Algorithm, Hossein Mirzaaghabeik, Nuha S. Mashaan, Sanjay Kumar Shukla

Research outputs 2022 to 2026

Ultra-high-performance concrete (UHPC) has attracted considerable attention from both the construction industry and researchers due to its outstanding durability and exceptional mechanical properties, particularly its high compressive strength. Several factors influence the shear capacity of UHPC deep beams, including compressive strength, the shear span-to-depth ratio (λ), fiber content (FC), vertical web reinforcement (ρsv), horizontal web reinforcement (ρsh), and longitudinal web reinforcement (ρs). Considering these factors, this research proposes a novel hybrid algorithm that combines an adaptive neuro-fuzzy inference system (ANFIS) with an artificial neural network (ANN) to predict the shear capacity of UHPC deep beams. To achieve this, ANN and …

Stress Reactivity And Sociocultural Learning: More Stress-Reactive Individuals Are Quicker At Learning Sociocultural Norms From Experiential Feedback, Shilpa Madan, Krishna Savani, Pranjal H. Mehta, Desiree Y. Phua, Ying-Yi Hong, Michael W. Morris

Research Collection Lee Kong Chian School Of Business

When interacting with others in unfamiliar sociocultural settings, people need to learn the norms guiding appropriate behavior. The present research investigates an individual difference that helps this kind of learning: stress reactivity. Interactions in an unfamiliar sociocultural setting are stressful, particularly when the actor fails to follow its rules. Although stress is typically considered a liability, more stress-reactive individuals may be more motivated to improve, and, thus, quicker to learn these rules. Consistent with this idea, a pilot study found that people genetically inclined to stress reactivity, as computed by a genetic profile score across 59 single nucleotide polymorphisms on …

Microplastics In Urine, Sputum And Lung Lavage Fluid From Patients With Respiratory Illnesses, Faezeh Jahedi, Neamatollah Jaafarzadeh Haghighi Fard, Mehdi Ahmadi, Afshin Takdastan, Maryam Haddadzadeh Shoushtari, Reza Dehbandi, Andrew Turner

School of Geography, Earth and Environmental Sciences

Because of the ubiquity of microplastics (MPs) in the environment there are concerns regarding human exposure. In this study, MPs have been determined in three physiological fluids: urine, sputum and bronchoalveolar fluid (BALF); from 30 adult patients in Iran with respiratory conditions. A total of nine small (20–100 μm) and mainly green and red fibres of polyethylene, polypropylene and polystyrene construction were detected in urine samples of eight participants. By contrast, 358 MPs that were dominated by small, white and transparent fibres, but also included larger (100–500 μm) fibres and fragments and spherules of various sizes, were detected in sputum …

Harnessing Redox-Active Molecules In Alkylammonium Halide-Based Eutectic Solvents For Redox Flow Batteries, Zeru Syum, Jesse Wainright, Desiree Mae Prado, Burcu Gurkan, Palani Sabhapathy, Clemens Burda, Matthew Vasil, Robert Savinell

Faculty Scholarship

Redox flow batteries (RFBs) are promising for large-scale energy storage, however, advancements in performance and cost-effectiveness are critical factors for adoption. Here we report on alkylammonium halide based eutectic solvents (ESs) and found that a ESs comprising of diethylammonium chloride or bromide, in ethylene glycol demonstrated exceptional stability and a wide electrochemical stability window, making it a promising candidate for RFB applications. The electrochemical stability and redox behavior of the alkylammonium halide-based ESs are significantly influenced by hydrogen-bonding interactions, modulated by the alkyl chain length of the cation and the nature of the anion. A redox-active eutectic electrolyte containing 0.45 …

Measuring The Relationship Between Oil Revenues And The Parallel Exchange Rate In Iraq For The Period (2003-2023): An Empirical Study, Saif Nihad Salim, Safaa Ali Hussein Al-Bakri

Journal of Economics and Administrative Sciences

This study is an empirical investigation into the relationship between oil revenues and the parallel exchange rate in Iraq during the period from 2003 to 2023, highlighting the susceptibilities of a rentier economy dependent overwhelmingly on oil exports. The study adopted a deductive procedure coupled with econometric analysis using the Autoregressive Distributed Lag (ARDL) method to analyze the impacts of oil revenues and GDP without oil on the parallel exchange rate. Annual data were gathered from official Iraqi agencies and subjected to unit root tests, bounds cointegration tests, and error correction model (ECM) tests. The results indicate a statistically significant …

Strategic Monitoring And Its Impact On Organizational Sustainability: An Analytical Study In Baghdad Health Directorates (Karkh, Rusafa, And Medical City), Rawad Ali Rahal, Suheir Adel Hamed

Journal of Economics and Administrative Sciences

This paper analyzes how Strategic Monitoring (SM) affects the Organizational Sustainability (OS) of some selected Baghdad Health Directorates in Iraq and attempts to establish how economic, social, and environmental sustainability can be achieved through SM, which includes strategic intelligence, strategic thinking, and strategic vigilance. A descriptive-analytical methodology has been used in which data was gathered using a structured questionnaire administered to 60 middle management officials of the directorates. The data were processed through suitable statistical tools using regression and correlation methods with the help of SPSS software. Results indicate that there exists a strong and significant positive relationship between SM …

Enabling Automatic Solar Pv Array Identification Using Big Satellite Imagery, Qi Li, Keyang Yu, Carson Snow, Dong Chen

Computer Science Faculty Research and Publications

Recently, there has been a growing interest in automatically collecting distributed solar photovoltaic (PV) installation information in smart grid systems, including the quantity and locations of solar PV deployments, as well as their profiling information across a given geospatial region. Most recent approaches are still suffering low detection accuracy due to insufficient sample and principal feature learning when building their models and also separation of rooftop object segmentation and identification during their detection processes. In addition, they cannot report accurate multi-deployment results. To address these problems, we design a new system-SolarDetector+, which can automatically and accurately detect and profile distributed …

Emulating Empire: Washington’S Preoccupation With British Counterinsurgency In Malaya And U.S. Commitment To Vietnam, Wen-Qing Ngoei

Research Collection College of Integrative Studies

This essay examines how Washington’s deep preoccupation with the British-Malayan counterinsurgency tactics–tactics that routed the guerilla fighters of the Malayan Communist Party–shaped US commitment to Vietnam. This US preoccupation, stoked by Britain’s (and Malaya’s) promotion of their counterinsurgency knowledge to US leaders, also influenced the lessons that US analysts and thinkers absorbed from the United States’ defeat in Indochina. Most studies of British-Malayan counterinsurgency and its connection to the Vietnam War fixate upon debating the relevance of the former to the latter and how this bears on US failures in Indochina. However, this essay focuses on the understudied fervor with …

On-Site Water Management Field Sampling Plan (Fsp), 2025 Update, Mark Thompson, Rampart Solutions

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Revised Draft Final Butte Priority Soils Operable Unit (Bpsou) Unreclaimed Sites: Ur-03 Site Remedial Action Work Plan (Rawp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Final Butte Priority Soils Operable Unit (Bpsou) Unreclaimed Sites: Ur-03 Site Remedial Action Work Plan (Rawp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Exploring Effective Institutional Strategies To Retain Adult Learners In Undergraduate Online Programs At A Faith-Based Institution, Fernando Rodriguez-Ramos

Electronic Theses and Dissertations

The aim of this qualitative research study was to identify dynamic advising and high-impact educational practices employed by advisors and faculty that prevent dropout and improve online adult learners’ performance and retention in undergraduate courses at a 4-year private, faith-based institution in the southwestern United States. This study explored the impact of these practices from the students’, faculty’s, and advisors’ perspectives to provide suggestions for improvement that would help retain these students in the classroom and the institution. The problem this study explored was that adult learner dropout from online higher education institutions is a persistent and increasing issue faced …

Testing For Broad Alternatives In Stratified Contingency Tables, Nan Mi

Dissertations

In medical and social sciences fields, data are measured in terms of discrete categories. The primary question of interest involves the relationship between a set of factors and a set of response variables under studies. Moreover, the distribution of the response variables may be influenced by another set of variables called confounders. The data from such studies are summarized in 3-way tables. The hypothesis we are interested in can be expressed in terms of "no partial association" between the sub-populations and the response levels.

The methods for testing the association or independence in a 2x2 contingency table have been developed, …

Runtime Backdoor Detection For Federated Learning Via Representational Dissimilarity Analysis, Xiyue Zhang, Xiaoyong Xue, Xiaoning Du, Xiaofei Xie, Yang Liu, Meng Sun

Research Collection School Of Computing and Information Systems

Federated learning (FL), as a powerful learning paradigm, trains a shared model by aggregating model updates from distributed clients. However, the decoupling of model learning from local data makes FL highly vulnerable to backdoor attacks, where a single compromised client can poison the shared model. While recent progress has been made in backdoor detection, existing methods face challenges with detection accuracy and runtime effectiveness, particularly when dealing with complex model architectures. In this work, we propose a novel approach to detecting malicious clients in an accurate, stable, and efficient manner. Our method utilizes a sampling-based network representation method to quantify …

Nexusgs: Sparse View Synthesis With Epipolar Depth Priors In 3d Gaussian Splatting, Yulong Zheng, Zicheng Jiang, Shengfeng He, Yandu Sun, Junyu Dong, Huaidong Zhang, Yong Du

Research Collection School Of Computing and Information Systems

Neural Radiance Field (NeRF) and 3D Gaussian Splatting (3DGS) have noticeably advanced photo-realistic novel view synthesis using images from densely spaced camera viewpoints. However, these methods struggle in few-shot scenarios due to limited supervision. In this paper, we present NexusGS, a 3DGS-based approach that enhances novel view synthesis from sparse-view images by directly embedding depth information into point clouds, without relying on complex manual regularizations. Exploiting the inherent epipolar geometry of 3DGS, our method introduces a novel point cloud densification strategy that initializes 3DGS with a dense point cloud, reducing randomness in point placement while preventing over-smoothing and overfitting. Specifically, …