Digital Commons Network^™

Potent Acridone Antimalarial Against All Three Life Stages Of Plasmodium, Papireddy Kancharla, Rozalia A. Dodean, Yuexin Li, Xiaowei Zhang, Sean Kelly, Jordan Charlton, Angley Binauhan, Laurize Garcia, Diana Caridha, Jane X. Kelly, Multiple Additional Authors

Chemistry Faculty Publications and Presentations

New antimalarial therapeutics ideally should target all three major life cycle stages. Here we present an acridone antimalarial chemotype that is potent against blood, liver, and mosquito stages of malaria parasites, with the potential for single-dose cure of bloodstream infections, radical cure of liver infections, and blocking of transmission to mosquitoes. Attributes of lead candidate T111 include potent in vitro activity against cultured parasites, ex vivo activity against clinical isolates, oral single dose cure in an asexual blood stage rodent model, inhibition of sexual blood stage parasites, activity against relapsing parasites in non-human primate liver cells, prevention of parasite development …

An Fgfr-P53 Developmental Signaling Axis Drives Salivary Cancer Progression, Julia M. R. Billington

USF Tampa Graduate Theses and Dissertations

Mucoepidermoid carcinoma (MEC) is the most frequently occurring salivary gland malignancy.Here, we investigated transcriptomic profiles of human fetal and adult salivary glands and MEC tumors to assess programs involved in MEC progression. Molecular and genetic analyses revealed that MEC tumors and fetal salivary glands share proliferative and developmental gene expression profiles that implicate an FGFR-p53 signaling axis in salivary MEC progression. Based on these findings, we developed a genetically engineered mouse model of advanced MEC via targeted expression of the CRTC1-MAML2 oncogene in salivary ductal cells. Specifically, CRTC1- MAML2 expression combined with p53 dysregulation in salivary ducts rewires FGF signaling …

The Political Philosophy Of Habitude: Conservatism Analytically Explained, Kyle S. Hodge

USF Tampa Graduate Theses and Dissertations

Conservatism is both undertheorized and poorly understood in philosophical political theory; all extant theories have proven deficient. They either conflate what is contingently associated with conservatism with its essence, draw mistaken generalizations from apparently conservative behavior, or else are explanatorily incomplete.

To avoid these deficiencies, I develop a rigorous, theory-neutral groundwork for evaluating theories of conservatism. This groundwork utilizes both traditional methods of analytic philosophy and, for the first time in the field, historiometry. Philosophical analysis determines the formal requirements of a successful explanation while empirical, historiometric data determines the most salient conservative exemplars whom any such theory must explain. …

Past Intrusion Of Circumpolar Deep Water In The Ross Sea: Impacts On The Ancient Ross Ice Shelf, Lucilla Capotondi, Gesine Mollenhauer, Tommaso Tesi, Francesco Muschitiello, Alessio Nogarotto, Jens Hefter, Chiara Pambianco, Simon Belt, Mathia Sabino, Francesca Battaglia, Federico Giglio, Alessio Di Roberto, Enrico Pochini, Andrea Geniram, Ester Colizza, Fiorenza Torricella, Giulia Giorgetti

School of Geography, Earth and Environmental Sciences

The Ross Ice Shelf, Antarctica’s largest by area, may face increased instability under future warming, threatening the Antarctic Ice Sheet. Understanding its past response to climate change is critical for anticipating future sea-level rise. We present a multi-proxy reconstruction of ocean and cryosphere conditions in the Ross Sea over the past 40,000 years. Our data show that warm Circumpolar Deep Water reached the JOIDES Trough in the western Ross Sea shortly after the Last Glacial Maximum, coinciding with the retreat of an ancestral ice shelf. This oceanic warming aligns with a southward shift of both the westerly and easterly wind …

Harvey V. Miller Ave. Group, Llc

All Decisions

In this HP action, the Appellate Term reversed a lower court's decision, holding that HPD, as a properly named party, has standing to move for civil and criminal contempt and civil penalties against the landlord. The lower court had incorrectly deemed HPD a "nominal party." The appellate court clarified that an HP proceeding is part of a broad statutory enforcement mechanism, not just a landlord-tenant dispute, and HPD is an "interested party" with the primary responsibility for enforcing housing standards. The case was remitted to the Civil Court to determine the motion on its merits.

Do Anterior-Posterior Lumbar Fusions Provide More Short-Term Value Than Posterior-Only? An Application Of The Operative Value Index, Steven R. Glener, Advith Sarikonda, D. Mitchell Self, Ashmal Sami, Danyal Quraishi, Emily Isch, Arbaz A. Momin, Cheritesh R. Amaravadi, Jack Jallo, Joshua Heller, Ashwini Sharan, Alex R. Vaccaro, Srinivas K. Prasad, James Harrop, Nicholas J. Clark, Ahilan Sivaganesan

Department of Neurosurgery Faculty Papers

BACKGROUND: Lumbar fusion is a common treatment for degenerative spine changes. Although both anterior-posterior (AP) and posterior-only approaches are used, their cost-effectiveness remains uncertain. This study aims to compare the costs and short-term "value" (outcomes per dollar spent) of AP and posterior-only lumbar fusions using time-driven activity-based costing and patient-reported outcomes.

METHODS: A retrospective review of AP and posterior lumbar fusions from 2017 to 2022 was conducted. Time-driven activity-based costing was used to assign intraoperative costs based on resource utilization, and the Oswestry Disability Index (ODI) was collected preoperatively and 3 months postoperatively. The Operative Value Index (OVI) was defined …

Impact Of Oceanographic Gradients And Marine Heatwaves On The Picophytoplankton Community In The Northern California Current System, Kristin E. Forgrave, Carey P. Sweeney, Melissa Steinman, Anvita U. Kerkar, Timothy M. Pettit, Anne W. Thompson

Biology Faculty Publications and Presentations

The Northern California Current (NCC) system is a productive coastal ecosystem with a mosaic of temporal and spatial features. The phytoplankton community plays a crucial role in supporting the rich ecosystem and economically important fisheries of the NCC. Our study integrates data across two years (2022-2023) and multiple transects to investigate the community composition of two major phytoplankton groups in the NCC: picocyanobacteria and photosynthetic picoeukaryotes (PPE). The abundances and cell sizes of the phytoplankton were measured using flow cytometry. We found PPE present at similar concentrations in both summer and winter, while picocyanobacteria were much more abundant in the …

Fort Hays State University Tiger Weekly, June 27, 2025, University Relations

Tiger Weekly Newsletters

No abstract provided.

Second Reaction: Sea Bear: A Journey For Survival, Whitley Pylant

First Opinions, Second Reactions

No abstract provided.

Kinematic Analysis Of Olympic And Traditional Rowing Mechanics At Different Stroke Rates, Alfonso Penichet-Tomas, Sergio Calavia-Carvajal, Basilio Pueo, Lamberto Villalon-Gasch

International Journal of Exercise Science

International Journal of Exercise Science 18(7): 610-621, 2025. Rowing requires strength, endurance, and technique, where stroke efficiency depends on body mechanics, movement sequencing, and stroke rate, which impact speed transfer. This cross-sectional study investigates the role of kinematic differences in stroke mechanics as a key component of performance analysis in Olympic and Traditional rowing. Thirteen elite national-level female rowers (age: 26.9 ± 5.1 years; body mass: 60.6 ± 6.9 kg; height: 166.7 ± 6.7 cm) performed three stroke-rate conditions on two ergometer setups: an Olympic rowing ergometer and a modified ergometer with a static seat replicating Traditional rowing. The stroke …

The Effect Of Breakfast On A Resistance Training Session And Response In Female Collegiate Athletes, Haley Roberts, Yvette Figueroa, Jennifer Bunn, Patrick Davis

International Journal of Exercise Science

International Journal of Exercise Science 18(6): 591-609, 2025. Breakfast consumption has been shown to be an essential component to a healthy lifestyle in various populations, yet research in this area is limited among female athletes. This study aimed to examine the effect of breakfast consumption on collegiate female athletes during a resistance training session and their nutritional habits throughout the remainder of the day. Twenty-three female collegiate Division I athletes (basketball, volleyball, bowling, and soccer) during the offseason participated in this cross-over study. The study included three visits: baseline measures for heart rate (HR), blood glucose (BG), salivary cortisol (SC), …

Developing A Faith-Based Financial Literacy: A Case Study Of Micro, Small And Medium Enterprises In East Sepik Province Of Papua New Guinea, Jessica Torohama, Alice Napasu

Adventist Human-Subject Researchers Association

Financial Literacy is crucial for the success of Micro, Small, and Medium Enterprises (MSMEs). However, MSMEs operate without financial literacy knowledge. This qualitative case study explored the faith-based financial literacy model for MSMEs in the East Sepik Province of Papua New Guinea. The study aims to bridge the financial literacy gaps by creating a faith-based curriculum for MSME owners.

Accessibility To Communities Of Faith: Overcoming Unequal Access For People With Disabilities, Shannon M. Trecartin, Terrance P. Trecartin, Ernesto Douglas Venn

Adventist Human-Subject Researchers Association

This presentation explores the religious experiences of Adventist members with disabilities worldwide, focusing on their access to SDA education and participation in community practices like small groups, prayer meetings, and evangelism. It concludes with recommendations for congregations and church leaders to enhance inclusion and engagement.

Relationship Between Access To Adventist Education And Belief In The Spirit Of Prophecy, Safary Wa-Mbaleka, Karl G. D. Bailey

Adventist Human-Subject Researchers Association

Adventist education prepares students for service in this world and in the world to come, focusing on the mental, physical, social, and spiritual dimensions. This study based on the Global Church Member Survey (2023) investigated the relationship between access to Adventist education and belief in the Spirit of Prophecy of the members of the members of the Seventh-day Adventist Church.

The "N" Framework: A Teacher Knowledge Framework For Numeracy Across The Curriculum, Kathy O'Sullivan, Niamh O'Meara, Merrilyn Goos, Paul Conway

Numeracy

Governments and policymakers around the world are encouraging teachers to teach numeracy across the curriculum. This paper proposes a theoretical framework for the knowledge required to teach numeracy across multiple disciplines. The concept of teacher knowledge is complex and consists of many different facets of knowledge. This paper proposes a framework that integrates theories from existing models of general and subject specific teacher knowledge, along with a model of numeracy. The authors developed the "N" framework, an integrated framework of numeracy knowledge, subject specific knowledge, and pedagogical content knowledge. Each element is essential for teaching numeracy across the curriculum in …

Lessons Learned: Luis Jácome, Mercedes Cardona

Journal of Financial Crises

Luis Jácome was appointed president of the board of Ecuador’s central bank in 1998 by newly elected President Jamil Mahuad. He and other members of the board resigned in 1999 in protest against a number of crisis-intervention measures they saw as threatening the bank’s independence to set monetary policy. Since the 1970s, Ecuador’s economy had experienced a period of growth fueled by oil exports, but by the mid-1990s the economy was reeling from a series of shocks, among them: a sharp drop in the price of oil, the effects of severe flooding on the country’s agricultural production, and the cost …

Lessons Learned: Benoît Cœuré, Mercedes Cardona

Journal of Financial Crises

Benoît Cœuré held several positions in the French Treasury in the years leading to the Global Financial Crisis (GFC). He was an economic adviser to the director general of the French Treasury from 1997–2002, deputy chief executive and chief executive of the French debt management office from 2002–2007, and assistant secretary for multilateral affairs, trade, and development from 2007–2009. He served as chief economist and deputy director general in 2009–2011. He joined the European Central Bank (ECB) during the European Sovereign debt Crisis and was responsible for market operations, market infrastructure supervision and European and international relations as a member …

Lessons Learned: Miguel Carcaño, Mercedes Cardona

Journal of Financial Crises

During the Global Financial Crisis (GFC), Miguel Carcaño served as head of the Spanish Treasury’s Fund for Orderly Bank Restructuring, the authority in charge of managing the restructuring process of the country’s credit institutions. The fund, known today as the Spanish Executive Resolution Authority, is integrated into the European network led by the Single Resolution Board (SRB) of the European Union’s banking union. Carcaño has held a number of posts within the SRB and in 2022 became head of the Single Resolution Fund, the SRB’s emergency fund, which serves as backstop for institutions across the banking union’s 21 countries.

Lessons Learned: Mark Branson, Mercedes Cardona

Journal of Financial Crises

Mark Branson joined the Swiss Financial Market Supervisory Authority (FINMA) as head of the banking division in 2010, during the European Sovereign Debt Crisis. He became deputy director of FINMA in 2013 and was named director a year later. Although Switzerland is not a member of the European Union (EU) or its banking union, the nation participates in bilateral agreements that govern trade with the EU, its largest trading partner. In the wake of the Global Financial Crisis (GFC), it enacted a number of regulations to improve oversight of the financial sector. Branson left FINMA in 2021 to become head …

United States: Rhode Island Limited Bank Holiday, 1991, Ayodeji George, Sophia Alden

Journal of Financial Crises

In 1990, the Rhode Island Share and Deposit Indemnity Corporation (RISDIC) was a private mutual deposit insurance corporation funded by member institutions. Late that year, after the failures of two of its insured institutions in July and October, other RISDIC member institutions faced large depositor withdrawals, as concerns began to focus on the financial health of RISDIC itself. RISDIC had maintained inadequate reserves, and on December 31, 1990, it found itself lacking the resources to cover depositor withdrawals from member institutions. RISDIC leadership requested a state-appointed conservator, which meant that all its member institutions no longer had the deposit insurance …

Survey Of Bank Holidays And Fund Suspensions, Rosalind Z. Wiggins, Owen Heaphy, Anmol Makhija, Stella Schaefer-Brown, Greg Feldberg, Andrew Metrick

Journal of Financial Crises

In this paper, we analyze seven case studies involving bank holidays and two involving mutual fund suspensions produced by the Yale Program on Financial Stability. Our main purpose is to assist policymakers who are considering utilizing a bank holiday in designing the most effective program as efficiently as possible. We find that a bank holiday may be most useful when designing and implementing a comprehensive remedy to an underlying problem distressing banks, particularly when an exogenous shock rather than balance sheet weaknesses is the cause of general distress to the system. A holiday is also useful to “ring-fence” one or …

Investigation Of Neuropsychological Symptoms And Changes In Gut Microbiome Physiology As Risk Factors For Chemotherapy-Induced Nausea In Patients With Breast Cancer, Komal P. Singh

Sigma Foundation for Nursing Research Grant Reports

The primary objective of this study was to investigate associations between chemotherapy-induced nausea (CIN) and gut microbiome characteristics over one cycle of chemotherapy.

Estimating Order Picking Distances Using Machine Learning, Hector J. Carlo, Carlos A. Morel-Figueroa, Victoria Méndez-González, Yamilette Boscio-Sánchez, Alex Demel-Pacheco

International Material Handling Research Colloquium

No abstract provided.

Factors Contributing To Low Back Pain Among Field Workers In Tanzania, Gerson De Leone, Don Noval, Amany Lorino, Ryan Lorino, Ruth Kajiru Nyika, Sozina Katuli

Adventist Human-Subject Researchers Association

Working in rice fields presents challenges to health that have grave consequences beyond back pain. Men and women in Kihurio village engage on a series of rice planting activities that affect the back. This study explores the factors to back problem in Tanzania and thrives to Identify corrective measures.

Impact Of Climate Change On Students: A Case Study, Florence Zimunya, Constance Chifamba, Elisha Chembwa

Adventist Human-Subject Researchers Association

Climate change poses fundamental threats to humans, especially students. The researchers carried out a descriptive Qualitative case study with 34 participants. Findings indicate that climate change has a host of negative impacts on students. The study recommends adequate disaster preparedness in schools and communities to ensure they develop coping strategies.

Agronomic Methods To Increase Pastureland Production In Mediterranean Marginal Areas, P Bullitta, Simonetta Bullitta, P P. Roggero

IGC Proceedings (1977-2023)

Sardinian pasturelands covering 1.200.000 ha represent nearly the 50 % of the island surface and are the most import­ant resource for animal feeding. Pastureland productivity is scarce, annual dry matter ranging from 6 to 12 q ha-1. Low pro­duction is mainly due to climate, scarce deepness and type of soils and by competition of mediterranean shrubs, mainly Cistus spp. that infests nearly 500.000 ha with a percentage of covering ranging from 20 to 100 % . The control of Cistus is normally done by means of fire and by ploughing but results are poor because a correct management of the …

Diagnostics Des Conduites De Paturage Tournant Et Continu Chargement, Hauter D'Herbe Et Jours D'Avance, J L. Fiorelli, J Husson, B Lavalette, E Vaubernier

IGC Proceedings (1977-2023)

L'efficacite d'une conduite de paturage reside dans son apti­tude a favoriser la production animale au moyen, notamment, de la mise a la disposition du troupeau d'une ressource herbacee la moins limitante possible (en quantite et en qualite) par rapport au potentiel de production des animaux et ce, le plus longtemps et le plus regulierement possible durant la periode de vegetation. Si le resultat zootechnique est generalement assez aisement evaluable, par contre les modalites de conduite du paturage ne sont que fort peu considerees. En consequence, aucun diagnos­tic ne peut etre correctement etabli et les recommendations d'amelioration eventuelle restent le plus …

Efficiency Measurement Of Pasture Use On Dairy Farms, G J. Piggot, D G. Clayton

IGC Proceedings (1977-2023)

Dairy farmers in northern regions of New Zealand look to Ruakura Research Station to provide them with technical information on farm production. Ruakura farms are outstand­ing examples of fully pasturefed dairy technology. In regions distant from the research station, such as Northland, parochial attitudes inhibit the complete extension of research station results. The project described here aimed to examine the current management practices on typical dairy farms in North­land. By identifying differences between Northland farms and Ruakura research farms, corrective management strategies could be recommended in order to increase dairy farm efficiency in the region.

Corn Stover In Comparison With Pasture Hay For Beef Production In Temperate Areas Of Argentina, J A. Josifovich, J Carrete

IGC Proceedings (1977-2023)

The amount of corn stover left in the fields after the harvest in the humid Pampa of Argentina can be estimated in 18 mil­lions tons. Even large part of these residues are grazed by bovines, in general this is done in fall, after harvest, during short periods (Josifovich, 1975), (Maddaloni, 1981), (Fattet, 1981). Part of this large amount of forage can be transferred to winter as large round bales. The efficiency of these reserves can be more useful in winter, during the dry season. Due to low quality these residues can't be used alone, with confined anim­als (Jackson, 1978; Maddaloni …

Production De Viande Bovine Et Ovine Sur Prairie Dans Les Monts Sudetes, Janina Fatyga

IGC Proceedings (1977-2023)

Par suite du depeuplement des villages et de !'abandon de la culture dans des zones situees en altitude dans !es Sudetes, on y observe l'accroissement de la superficie des paturages perma­nents. Des 1968, on y cree des zones de pature OU en ete de jeu­nes bovins et des ovins provenant des fermes situees plus bas sont conduits en permanence. L'importance du phenomene est illustre par le fait qu'a present, sur le terrain d'une seule region de Walbrzych, il y a 103 bases de pature d'une superficie de 7.000 ha, appartenant a 54 fermes d'etat ou paissent environ 25.000 ovins et …