Digital Commons Network^™

The Perceived Impact Of Officer-Involved Domestic Violence On Law Enforcement Administrators, Victoria Smith

Walden Dissertations and Doctoral Studies

The frequency of officer-involved domestic violence (OIDV) is a serious problem in the law enforcement profession. This qualitative phenomenological study aimed to determine what measures and specific domestic violence policies are working well and what is working poorly in Florida. This study is critical because it can aid upcoming law enforcement administrators (LEAs) and current LEAs in improving the policies and measures they use in their agency to combat OIDV among their officers and recruits. Jacques’s organizational culture theory (OCT) provided a framework for this study. I used purposeful snowball sampling methods to recruit participants for this study. Six law …

Early Detection Of Oak Wilt Using Unmanned Aerial Vehicles (Uav) & Computer Vision, Muttaki I. Bismoy

Masters Theses

Forests are critical ecosystems, delivering services such as biodiversity conservation, climate regulation, timber production, and recreation. However, they face increasing threats from pathogens like Bretziella fagacearum, which causes Oak Wilt, a lethal disease that disrupts water transport in oak trees, leading to canopy dieback and eventual death. Traditional detection methods rely on manual ground surveys, which are labor-intensive, time-consuming, and prone to error, particularly in early disease stages.

This research presents an automated, scalable, high-precision Oak Wilt detection system using Unmanned Aerial Vehicles (UAVs) combined with deep learning-based computer vision. Expanding on earlier work with a lightweight CNN achieving an …

Teaching Bilingual Learners With Dysgraphia, Angela Gonzalez-Urbina

Masters Projects

With the push for legislation on the Dyslexia law in Michigan and elsewhere, teachers need to understand what dyslexia and dysgraphia are to support all students. An extra understanding is necessary in bilingual education and reading challenges because they use two language systems in and out of the classroom. Reading and writing are already areas that impact the working memory of the learner; adding dysgraphia to that proves to be more of a challenge. Dysgraphia can coexist with dyslexia, and individuals with dysgraphia often experience difficulties with spelling and writing speed. This project introduces dysgraphia as one of the reading …

Genomic Editing Of A Pathogenic Sequence Variant In Acta2 Rescues Multisystemic Smooth Muscle Dysfunction Syndrome In Mice, Qianqian Ding, Peiheng Gan, Zhisheng Xu, Hui Li, Lei Guo, Camryn Macdonald, Wei Tan, Efrain Sanchez-Ortiz, John R Mcanally, Yu Zhang, Dileep Karri, Lin Xu, Ning Liu, Eric N Olson

Faculty, Staff and Student Publications

Background: Vascular smooth muscle cells (SMCs), the predominant cell type in the aortic wall, play a crucial role in maintaining aortic integrity, blood pressure, and cardiovascular function. Vascular SMC contractility and function depend on ACTA2 (smooth muscle α-actin 2). The pathogenic variant ACTA2 c.536G>A (p.R179H) causes multisystemic smooth muscle dysfunction syndrome, a severe disorder marked by widespread smooth muscle abnormalities, resulting in life-threatening aortic disease and high risk of early death from aneurysms or stroke. No effective treatments exist for multisystemic smooth muscle dysfunction syndrome.

Methods: To develop a comprehensive therapy for multisystemic smooth muscle dysfunction syndrome, we used …

Optimizing Motion Management And Baseline Shifts In Magnetic Resonance-Guided Spine Stereotactic Body Radiation Therapy, Yao Ding, Travis C Salzillo, Debra N Yeboa, Martin C Tom, Zhiheng Wang, Parmeswaran Diagaradjane, Ergys Subashi, Jinzhong Yang, Todd Swanson, Thomas Beckham, Chenyang Wang, Amol J Ghia, Tina Briere, Jihong Wang, Fabienne Lathuilière, Sneha Cloake, Eun Young Han

Faculty, Staff and Student Publications

BACKGROUND: Stereotactic body radiation therapy (SBRT) has proven effective in controlling spinal lesions with minimal toxicity, primarily due to its ability to limit spinal cord dose. Recent advances in MR-linac (MRL) technology offer superior spinal cord visualization and real-time gating, which can facilitate dose escalation in spinal tumor treatment while maintaining safety.

PURPOSE: This study aimed to optimize motion management for spine SBRT on an MRL by analyzing patient-specific motion dynamics and evaluating the most effective registration structures. We hypothesized that baseline shifts (BLS) would improve delivery efficiency while maintaining spinal cord dose constraints. The goal was to establish displacement …

The Impact Of Maternal Diabetes On Sacral Agenesis: A Paediatric Report, Gabriella M. Calabrese, Márcio L. Duarte, Leonardo F. Freitas, Eduardo O. Narvaez

Sultan Qaboos University Medical Journal

No abstract provided.

The Sketches Of Infinite Data And Algorithms For Real-Time Data Insights, Vishnu S. Pendyala

Open Educational Resources

How are machine learning algorithms able to answer questions from any nook and corner of the World Wide Web? How are trending hashtags from the near infinite microblog posts, unique visitors and other distinct counts in the near infinite website traffic determined? How do blogging websites avoid recommending articles a user has previously read? In general, how can we answer complex queries about enormous data streams without storing them entirely, in real-time? The answer often lies in clever approximation algorithms and data "sketches" that capture essential properties using vastly reduced space. The relentless flow of data in modern systems indeed …

Trpc4 Regulates Limbic Behavior And Neuronal Development By Stabilizing Dendrite Branches Through Actomyosin-Driven Integrin Activation, Jaepyo Jeon, Travis I Moore, Insuk So, Marc Freichel, Veit Flockerzi, Lutz Birnbaumer, Michael X Zhu

Faculty, Staff and Student Publications

Transient Receptor Potential Canonical 4 (TRPC4) channels have been implicated in multiple neurological functions, including anxiety and sociability. TRPC4 variants were also found in patients with autism. However, the contributions of TRPC4 to neurodevelopment remain undefined. Here, we show that neurobehavioral deficits appear early in young TRPC4 knockout (Trpc4^−/−) mice immediately after weaning, manifesting as alterations in multiple, limbic-related behaviors, such as nesting, marble burying, burrowing, self-grooming, and social interactions. Hippocampal neurons of Trpc4−/− mice exhibit reduced dendritic arborization both in vivo and in vitro. Mechanistically, we found that TRPC4 expression in dendrites surged at the …

Causes Of Symptoms And Symptom Persistence In Long Covid And Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Anthony L Komaroff, Robert Dantzer

Faculty, Staff and Student Publications

Debilitating symptoms for many years can follow acute COVID-19 ("long COVID"), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and various post-acute infection syndromes (PAISs). Together, long COVID and ME/CFS affect 60-400 million individuals, globally. Many similar underlying biological abnormalities have been identified in both conditions including autoantibodies against neural targets, endothelial dysfunction, acquired mitochondrial dysfunction, and a pro-inflammatory gut microbiome. Each of these abnormalities may directly cause some of the symptoms. In addition, the symptoms also may be caused by ancient, evolutionarily conserved symptomatic and metabolic responses to vital threats-sickness behavior and torpor-responses mediated by specific, recently discovered neural circuits. These neural …

Experience-Dependent Intrinsic Plasticity In Layer Iv Of Barrel Cortex At Whisking Onset, Molly C Shallow, Lucy Tian, Bryan T Higashikubo, Hudson Lin, Katheryn B Lefton, Siyu Chen, Joseph D Dougherty, Joe P Culver, Mary E Lambo, Keith B Hengen

2020-Current year OA Pubs

The development of motor control over sensory organs is a critical milestone, enabling active exploration and shaping of the sensory environment. Whether the onset of sensory organ motor control directly influences the development of corresponding sensory cortices remains unknown. Here, we confirm and exploit the late onset of whisking behavior in mice to address this question in the somatosensory system. Using ex vivo electrophysiology, we describe a transient increase in the intrinsic excitability of excitatory neurons in layer IV of the barrel cortex, which processes whisker input, immediately following the onset of active whisking on postnatal days 13 and 14. …

Screening And Variable Selection For Analyzing Binary Outcome With Rare Events And High-Dimensional Predictors, Mohammad Nahian Ferdous Abrar

Electronic Theses and Dissertations Archive

Binary outcomes with rare events (event rate less than 5%) present significant analytical challenges, particularly in high-dimensional settings such as epigenome-wide association studies (EWAS) involving DNA methylation data. Traditional logistic regressions are often inadequate under these conditions, suffering from bias, high variance, and diminished power when the event rate is low and the number of predictors exceeds the sample size (p >> n). To address these limitations, we developed a series of novel methods that enhance sensitivity and accuracy in identifying biologically meaningful biomarkers while accounting for both event rarity and high dimensionality. We first introduce two innovative screening approaches. The …

The Intersection Of Social Groups And The Self, Zachary Robert Auwerda

Electronic Theses and Dissertations Archive

This dissertation explores the nature of social identity by examining both the collective identity of groups and the social selves of individuals. I start by offering a Humean model of collective identity. On this model, the metaphysical nature of group persistence depends on our psychological dispositions and our explanatory goals. On this view, collective identity is a fiction—something that humans ascribe to a group—rather than something that exists independently. I argue that this Humean model has advantages over structural and intentional theories of group persistence. I then move onto the topic of social construction and its incompatibility with methodological individualism. …

Prioritising Time-Critical Injuries And Interventions For Trapped Motor Vehicle Collision Patients: A Delphi Study, Tim Nutbeam, Rob Fenwick, Ian Marritt, Brian Lee, Luke Staveley-Wadham, Nigel Lang, Louise Johnson, Nicolas Mattock, Jane Ogilvie, Emily Foote, Francis Screech, Lara Lebeau–Humarau, Caroline Leech

Peninsula Medical School

Background Physically trapped patients following motor vehicle collisions are at high risk of time-critical injuriesand poor outcomes. Despite this, there is limited consensus on which injuries should be prioritised and which earlyinterventions are both necessary and feasible in the prehospital setting. This study aims to develop expert consensuson injury categorisation and the delivery of early care interventions to guide clinical and operational decision-makingat the scene.Methods A modified Delphi method was used to gather consensus from a multidisciplinary panel of subjectmatter experts, including clinicians, paramedics, and members of fire and rescue services. In Round 1, participantscontributed to the development of draft …

Efficient Decontamination Of Organophosphate-Based Pesticides And Nerve Agent Simulants Mediated By N-Containing Nucleophiles, Emmanuel Kingsley Darkwah, Puspa Aryal, Saidulu Todeti, Jared Kenik, Samuel Insall, V. Prakash Reddy, Chariklia Sotiriou-Leventis

Chemistry Faculty Research & Creative Works

There is a growing interest in developing safer and more effective decontaminating agents for organophosphate-based pesticides and nerve agents. In this study, we present an effective method for the nonaqueous decontamination of these compounds using small-molecule-based decontaminating agents under ambient conditions. Our approach utilizes aryl and heteroaryl carboxaldehyde hydrazones and hydrazides to effectively hydrolyze nerve agent simulants into their nontoxic degradation products. The effectiveness of this method was evaluated using a range of nerve agent simulants, including dimethyl 4-nitrophenyl phosphate (DMNP), dimethyl methyl phosphonate (DMMP), and triphenyl phosphate (TPhP). In the presence of the heteroaryl hydrazone, the rate of hydrolysis …

Changes In Self-Reported Excessive Daytime Sleepiness Are Associated With 5-Year All-Cause Mortality Risk Among Veterans, Katherine G Bay, Arash Maghsoudi, Amin Ramezani, Drew A Helmer, Amir Sharafkhaneh, Javad Razjouyan

Faculty, Staff and Students Publications

Excessive daytime sleepiness (EDS) is linked to adverse clinical outcomes. This study evaluated changes in a validated tool to assess EDS, the Epworth Sleepiness Scale (ESS) and mortality risk. This retrospective cohort study included Veterans receiving sleep-related services in the Department of Veterans Affairs (VA) from October 4, 1999 to August 18, 2018, with two qualifying ESS measures. ESS values were extracted from patient notes using a validated natural language processing (NLP) pipeline (96% accuracy). ESS scores were categorised as Normal (0-10) or Abnormal (11-24). Patients were grouped based on ESS changes: Normal-Normal, Normal-Abnormal, Abnormal-Abnormal and Abnormal-Normal. Cox proportional hazards …

Dna Methylation Signatures Of Cardiovascular Health Provide Insights Into Diseases, Madeleine Carbonneau, Yi Li, Yishu Qu, Yinan Zheng, Alexis C Wood, Mengyao Wang, Chunyu Liu, Tianxiao Huan, Roby Joehanes, Xiuqing Guo, Jie Yao, Kent D Taylor, Russell P Tracy, Peter Durda, Yongmei Liu, W Craig Johnson, Wendy S Post, Tom Blackwell, Jerome I Rotter, Stephen S Rich, Susan Redline, Myriam Fornage, Jun Wang, Hongyan Ning, Lifang Hou, Donald Lloyd-Jones, Kendra Ferrier, Yuan-I Min, April P Carson, Laura M Raffield, Alexander Teumer, Hans J Grabe, Henry Völzke, Matthias Nauck, Marcus Dörr, Arce Domingo-Relloso, Amanda Fretts, Maria Tellez-Plaza, Shelley A Cole, Ana Navas-Acien, Meng Wang, Joanne M Murabito, Nancy L Heard-Costa, Brenton Prescott, Vanessa Xanthakis, Dariush Mozaffarian, Daniel Levy, Jiantao Ma

Faculty, Staff and Students Publications

Background: The association of overall cardiovascular health (CVH) with changes in DNA methylation (DNAm) has not been well characterized.

Methods: We calculated the American Heart Association's Life's Essential 8 score to reflect CVH in 5 cohorts with diverse backgrounds (mean age 54 years, 55% women, and enrollment year ranging from 1989 to 2012). Epigenome-wide association studies (EWAS) for Life's Essential 8 score were conducted, followed by bioinformatic analyses. DNAm loci significantly associated with Life's Essential 8 score were used to calculate a CVH DNAm score. We examined the association of the CVH DNAm score with incident cardiovascular disease (CVD), cardiovascular …

Putting Genai On Notice: Genai Exceptionalism And Contract Law, David Atkinson

NULR Online

No abstract provided.

Echocardiographic Assessment Of Pulmonary Hemodynamics And Right Ventricular Performance In Neonatal Murine Hypoxia, Kel Vin Woo, Philip T Levy, Carla J Weinheimer, Amanda L Hauck, Aaron Hamvas, David M Ornitz, Attila Kovacs, Gautam K Singh

2020-Current year OA Pubs

No abstract provided.

Pengaruh Model Challenge Based Learning Terhadap Keterampilan Berpikir Kritis Dan Hasil Belajar Siswa Pada Materi Bencana Alam Kelas V Sd, Elfa Diyah Kusuma, M. Anas Thohir, Lilik Bintartik

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Salah satu kemampuan yang sangat penting untuk pembelajaran di era modern adalah pemikiran kritis. Tujuan penelitian ini adalah untuk mengevaluasi bagaimana model pembelajaran berbasis tantangan berdampak pada keterampilan berpikir kritis siswa dan hasil belajar mereka tentang materi bencana alam di kelas V SD. Eksperimen semu (Quasi Exprimental Design) digunakan dengan tipe pre-test dan post-test Grup Kontrol NonEquivalen. Penelitian ini melibatkan 44 siswa kelas V SD dari dua kelas yang sama. Dalam penelitian ini, seluruh siswa kelas V SD diambil sebagai sampel. Metode pengumpulan data dengan menggunakan tes pilihan ganda dan esai. Uji MANOVA digunakan untuk menganalisis data. Hasil uji statistik …

“Wild Things Belong Outside”: An Ecofeminist Analysis Of Amy Greene’S Bloodroot, Karrah N. Davidson

Critical Humanities

Appalachian Literature has a canon of its own, one of which I believe Amy Greene’s groundbreaking novel, Bloodroot should be a more prominent part. The novel brings up important cultural as well as universal issues. Situating this work among relevant theory and scholarship allows us to think seriously about the themes that Green explores in the novel in a way that has not been done before. Additionally, I believe that there is important scholarly work to be done with the role of Appalachian Folk Magic in a world where some of these traditions and customs are dying out. Individuals within …

The Shorthorn: April 26, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: April 27, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: April 21, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: April 20, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: April 14, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: April 13, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: April 12, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: March 31, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: March 24, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: March 17, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.