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First Principles Materials Discovery And Design For Photovoltaic And Solar Thermal Alloys Using High Throughput Methods, Andrew Pike Aug 2025

First Principles Materials Discovery And Design For Photovoltaic And Solar Thermal Alloys Using High Throughput Methods, Andrew Pike

Dartmouth College Ph.D Dissertations

Materials selection has been a challenge since the dawn of time. With the advent of computational methods and high throughput databases, materials can be discovered and assessed before they are even synthesized. In this thesis I will discuss my work towards designing new materials for clean energy uses, especially alloys which have been underexplored from computational methods. To begin, I present a case study explaining the synthesis of the Yb14ZnSb11 thermoelectric material. Next, I explore the class of AM2Pn2 Zintl materials. From the previously identified BaCd2P2, it is suspected that …


Computational Detection Of Articulation Transients In Clarinet Performance, Whitney L. Coyle, Max Griffin, Makayle S. Kellison Aug 2025

Computational Detection Of Articulation Transients In Clarinet Performance, Whitney L. Coyle, Max Griffin, Makayle S. Kellison

Faculty Publications

Accurate measurement of note-to-note transitions is essential for analyzing articulation in clarinet performance. Traditional methods rely on either subjective amplitude thresholds—such as the time between 5% and 95% RMS levels—or direct measurement of tongue-reed contact time using reed-mounted sensors. These approaches are limited by their dependence on user-defined parameters or invasive hardware. This study proposes a computational alternative: ΔT, a curvature-based metric defined as the time interval between surrounding minima in the second derivative of the mouthpiece pressure envelope. Using data from a sensor-equipped mouthpiece (SEM), we compare ΔT to both threshold-based timing (Tt) …


Library Publishing Research Agenda (2nd Ed.), Talea Anderson, Karen Bjork, Leigh-Ann Butler, Nina Collins, Perry Collins, Matthew Goldberg, Jonathan Grunert, Matthew Hunter, Michelle Lalonde, John Martin, Shawn Martin, John David Morgenstern, Talia Perry, Christopher Popovich, Liz Scarpelli, Janet Swatscheno, Willa Tavernier, Dan Tracy, Michelle Wilson, Mai Yamamoto Aug 2025

Library Publishing Research Agenda (2nd Ed.), Talea Anderson, Karen Bjork, Leigh-Ann Butler, Nina Collins, Perry Collins, Matthew Goldberg, Jonathan Grunert, Matthew Hunter, Michelle Lalonde, John Martin, Shawn Martin, John David Morgenstern, Talia Perry, Christopher Popovich, Liz Scarpelli, Janet Swatscheno, Willa Tavernier, Dan Tracy, Michelle Wilson, Mai Yamamoto

LPC Publications

This second edition of the Library Publishing Research Agenda builds on the foundation laid by the original 2020 publication, continuing to explore critical areas where research is needed to inform and strengthen practice in the field of library publishing. It offers updated and expanded exploratory overviews of six key topics (assessment, labor, accessibility, non-traditional research outputs, peer review, and partnerships), each including a contextual summary, refreshed or newly proposed research questions, and updated resources for further reading. This edition reflects new developments in the field and ongoing conversations within the community. It is intended to support current and future researchers, …


2025 August 28 - From My Notepads Newsletter, Brian E. Noland, Office Of The President, East Tennessee State University Aug 2025

2025 August 28 - From My Notepads Newsletter, Brian E. Noland, Office Of The President, East Tennessee State University

From My Notepads: A Newsletter from President Brian Noland

No abstract provided.


Multidimensional Monotonicity And Economic Applications, Frank Yang, Kai Hao Yang Aug 2025

Multidimensional Monotonicity And Economic Applications, Frank Yang, Kai Hao Yang

Cowles Foundation Discussion Papers

We characterize the extreme points of multidimensional monotone functions from [0,1]n to [0,1], as well as the extreme points of the set of one-dimensional marginals of these functions. These characterizations lead to new results in various mechanism design and information design problems, including public good provision with interdependent values; interim efficient bilateral trade mechanisms; asymmetric reduced form auctions; and optimal private private information structure. As another application, we also present a mechanism anti-equivalence theorem for two-agent, two-alternative social choice problems: A mechanism is payoff-equivalent to a deterministic DIC mechanism if and only if they are ex-post equivalent.


Relationship Between Peer Support Services And Offender Reentry Organizations, Julie Megan Dixon Aug 2025

Relationship Between Peer Support Services And Offender Reentry Organizations, Julie Megan Dixon

Walden Dissertations and Doctoral Studies

This study addressed the gap in understanding the acceptability, appropriateness, and feasibility of peer support services (PSS) among two groups of reentry staff in North Carolina (NC): those in the community and those within the Department of Adult Correction (DAC). Both groups of reentry staff completed a web-based survey encompassing the Acceptability of Intervention Measure (AIM), Intervention Appropriateness Measure (IAM), and Feasibility of Intervention Measure (FIM). The sampling strategy, response rate, and survey administration details are provided. Guided by ecological systems theory, this study examined how PSS can improve reentry outcomes and address insufficient public safety, social relationship deterioration, and …


Committee's Motion For Summary Judgment On Charitable Immunity Defense Aug 2025

Committee's Motion For Summary Judgment On Charitable Immunity Defense

Catholic Dioceses in Bankruptcy

No abstract provided.


An Antioxidant Approach To Ameliorate The Effects Of Radiation And Chemotherapy On Cognition, Raymond Anan Otoo Aug 2025

An Antioxidant Approach To Ameliorate The Effects Of Radiation And Chemotherapy On Cognition, Raymond Anan Otoo

Theses and Dissertations

Acute Lymphoblastic Leukemia (ALL) is a hematologic malignancy that primarily affects children and young adults. While advancements in treatment—including chemotherapy and cranial irradiation—have significantly improved 5-year survival rates in children to nearly 90%, radiation-induced cognitive impairment (RICI) remains a persistent and debilitating side effect. The brain, particularly the hippocampus, is highly susceptible to radiation-induced oxidative stress and inflammation. In the treatment of ALL, the combined use of chemotherapy and radiotherapy contributes to a heightened oxidative burden, exacerbating the risk of cognitive dysfunction. Although previous studies have linked radiation exposure to neurocognitive decline, the molecular mechanisms underlying RICI and chemotherapy-induced cognitive …


Staff Education Project For Enhancing Medication Adherence In Mental Health: An Evidence-Based Education Program For Healthcare Practitioners In Outpatient Clinics, Rita Erina Pyuzza Aug 2025

Staff Education Project For Enhancing Medication Adherence In Mental Health: An Evidence-Based Education Program For Healthcare Practitioners In Outpatient Clinics, Rita Erina Pyuzza

Walden Dissertations and Doctoral Studies

The staff education project was designed to address medication non-adherence among mental health patients in an outpatient psychiatric clinic by enhancing the knowledge and skills of mental health nurses and nurse practitioners. The lack of structured, evidence-based training on medication adherence strategies has contributed to poor patient outcomes, increased hospitalizations, and higher healthcare costs. Clinic patient reports indicated 50% medication non-adherence, highlighting the need to address non-adherence through effective nursing-led education, medication management, and adherence monitoring. The project assessed whether enhancing the outpatient healthcare providers’ skills and knowledge through a structured, evidence-based program would improve the providers’ medication adherence strategies. …


Enhancing Technical Proficiency Of Collegiate Ballet Dancers Through Customized Strength And Conditioning Programs: An Empirical Study, Diedre Sakota Aug 2025

Enhancing Technical Proficiency Of Collegiate Ballet Dancers Through Customized Strength And Conditioning Programs: An Empirical Study, Diedre Sakota

Doctorate in Kinesiology

Objective: This empirical study was designed to compare the effectiveness of a structured strength training program to a skill-based conditioning program, enhancing ballet-specific movement efficiency. The selected parameters include hip external rotation, hip hyperextension strength, single leg jump height, dynamic balance, and technique proficiency. Methodology: Participants (n=10) were randomly assigned to a six-week intervention: Progressing Ballet Technique (PBT) or Weight Training (WT). Data was collected from the following assessments at baseline and collected again following the six-week intervention:single-leg jump height (JH), single-leg center of pressure (COP) landing deviations, dance- specific star balance excursion test (dsSEBT), hip external rotation (HER), hip …


Adult-Child Caregivers’ Fear And Coping Regarding The Risk Of Inheriting Alzheimer’S Disease, Rebecca Anne Ledbetter Aug 2025

Adult-Child Caregivers’ Fear And Coping Regarding The Risk Of Inheriting Alzheimer’S Disease, Rebecca Anne Ledbetter

Walden Dissertations and Doctoral Studies

Caring for elderly parents with Alzheimer’s disease (AD) poses two major challenges for adult-child caregivers: the tasks involved in taking care of ailing parents and also potentially living in fear of developing the same disease. This research examined how caregivers with such fear regard their vulnerability to AD and how they manage the stress that comes with caregiving for someone with a disease they dread developing themselves. This grounded theory study employed the appraisal theory of emotions and the theory of moods as frameworks and aimed to establish awareness regarding coping strategies that adult-child caregivers have about caretaking and their …


Comprehending Students' Experiences With A Language Learning Resource Center: A Descriptive Phenomenological Study Of College Life And Belonging, Paulina Dzieza Aug 2025

Comprehending Students' Experiences With A Language Learning Resource Center: A Descriptive Phenomenological Study Of College Life And Belonging, Paulina Dzieza

Dissertations

This study explores the impact of Language Learning Resource Center (LLRC) services on college students' overall college experience and their sense of belonging on campus. In the constantly evolving world of higher education, higher education institutions work to provide welcoming spaces where students can flourish academically and socially. In higher education, where there is a growing focus on student support services, the LLRC is essential for promoting academic achievement, cross-cultural interaction, and social integration for foreign language learners. This qualitative study, guided by a combined theoretical framework of Community of Practice and Ethics of Care, aims to advance knowledge of …


Influence Of Child Abuse On Youth Restiveness As Perceived By Security Personnel In Ilorin Metropolis, Kwara State, Falilat Anike Okesina Aug 2025

Influence Of Child Abuse On Youth Restiveness As Perceived By Security Personnel In Ilorin Metropolis, Kwara State, Falilat Anike Okesina

Jurnal Kajian Bimbingan dan Konseling

The rate at which Nigerian youths take up arms to perpetuate anti-social acts has become a major concern to the populace. This study investigated the influence of child abuse on youth restiveness as perceived by security personnel in Ilorin metropolis, Kwara State. The study was a survey research. The population of this study comprised all security personnel in Ilorin metropolis and 200 respondents were randomly selected for the study. A questionnaire entitled “Influence of Child Abuse on Youths Restiveness Questionnaire” (ICAYRQ) was used to collect data for the study. Percentage was used to analyse the demographic data. Mean and rank …


The Mediating Role Of Smartphone Usage In The Relationship Between Working Mothers And Children’S Social Interaction, Wulan Patria Saroinsong, Mochamad Nursalim, Azmawaty Binti Mohamad Nor Aug 2025

The Mediating Role Of Smartphone Usage In The Relationship Between Working Mothers And Children’S Social Interaction, Wulan Patria Saroinsong, Mochamad Nursalim, Azmawaty Binti Mohamad Nor

Jurnal Kajian Bimbingan dan Konseling

This study explores how smartphone usage acts as a mediator in the connection between working mothers and social interaction among children aged 3–6 years in East Java, Indonesia. Due to the insufficient reading and writing skills of children in this age range to complete questionnaires for the children’s interaction variable, data were gathered from their parents’ perspective, notably working mothers, who offered insights into their parenting behaviors and their children’s interaction patterns when using the smartphone. The research utilized a mediation analysis design to examine the relationships among the variables. A structured questionnaire was distributed to a sample of 400 …


Spartan Daily, August 28, 2025, San Jose State University, School Of Journalism And Mass Communications Aug 2025

Spartan Daily, August 28, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 4


The Immunophenotypic And Genetic Characterization Of Pediatric T -L Ymphoblastic Leukemia With A Mature Immunophenotype, Mahsa Khanlari, Wei Wang, Parastou Tizro, Mohammad K Eldomery Aug 2025

The Immunophenotypic And Genetic Characterization Of Pediatric T -L Ymphoblastic Leukemia With A Mature Immunophenotype, Mahsa Khanlari, Wei Wang, Parastou Tizro, Mohammad K Eldomery

Faculty, Staff and Student Publications

Not available.


August 28, 2025, James Madison University Aug 2025

August 28, 2025, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.


Faculty Senate Agenda, Georgia Southern University, Faculty Senate Aug 2025

Faculty Senate Agenda, Georgia Southern University, Faculty Senate

Faculty Senate Agendas

No abstract provided.


Feasibility Evaluation Of Secure Offline Large Language Models With Retrieval-Augmented Generation For Cpu-Only Inference, Erick Tyndall, Torrey J. Wagner, Colleen Gayheart, Alexandre Some, Brent T. Langhals Aug 2025

Feasibility Evaluation Of Secure Offline Large Language Models With Retrieval-Augmented Generation For Cpu-Only Inference, Erick Tyndall, Torrey J. Wagner, Colleen Gayheart, Alexandre Some, Brent T. Langhals

Faculty Publications

Recent advances in large language models and retrieval-augmented generation, a method that enhances language models by integrating retrieved external documents, have created opportunities to deploy AI in secure, offline environments. This study explores the feasibility of using locally hosted, open-weight large language models with integrated retrieval-augmented generation capabilities on CPU-only hardware for tasks such as question answering and summarization. The evaluation reflects typical constraints in environments like government offices, where internet access and GPU acceleration may be restricted. Four models were tested using LocalGPT, a privacy-focused retrieval-augmented generation framework, on two consumer-grade systems: a laptop and a workstation. A technical …


Mantle Flow And Fault Zone Related Seismic Anisotropy Revealed By A Dense Linear Broadband Array In Southeast Tibet, Jing Wu, Yinshuang Ai, Stephen S. Gao, Peixi Huang, Fansheng Kong, Deke Xu, Jianguo Song, Xinyu Gao, Mengyi Wei, Long Li, Jien Zhang, Yanbin Zhang, Yingying Zhang Aug 2025

Mantle Flow And Fault Zone Related Seismic Anisotropy Revealed By A Dense Linear Broadband Array In Southeast Tibet, Jing Wu, Yinshuang Ai, Stephen S. Gao, Peixi Huang, Fansheng Kong, Deke Xu, Jianguo Song, Xinyu Gao, Mengyi Wei, Long Li, Jien Zhang, Yanbin Zhang, Yingying Zhang

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Southeast Tibet, a key region for the southeastward extrusion of the Tibetan Plateau, remains debated in terms of its tectonic deformation in response to the ongoing collision between the Indian and Eurasian plates. In this study, we applied shear-wave splitting analysis of core-refracted phases recorded by a newly deployed dense seismic array and six permanent stations to delineate crustal and mantle deformation processes. The observed fast polarization directions are predominantly aligned NNW–SSE, while the splitting delay times vary across four sub-blocks. The anisotropy pattern suggests a dominantly asthenospheric origin, consistent with southeastward-directed mantle flow associated with the extrusion of the …


Pressure And Force Dynamics In Artificial Muscle Actuators: A State-Space And Optimization-Based Approach, Mohammad Elzein Aug 2025

Pressure And Force Dynamics In Artificial Muscle Actuators: A State-Space And Optimization-Based Approach, Mohammad Elzein

Dissertations and Theses

This two-part investigation explores the dynamic behavior of braided pneumatic actuators (BPAs) under bio-inspired pulse modulation, with the aim of improving their biomimetic force output and control. The first study examines the effect of pulse length and inter-pulse timing on BPA performance, revealing that force output is highly sensitive to the temporal structure of input pulses mirroring biological muscle behavior. Using dual-pulse actuation schemes, the results demonstrate that force responses exceed the additive contributions of individual pulses, with peak amplification occurring consistently at a 27 ms inter-pulse gap. Shorter pulse lengths (10–20 ms) yielded the highest normalized force increases, up …


C-C Motif Chemokine Receptor-Like 2 Promotes The Interferon-Γ Signaling Response In Myeloid Neoplasms With Erythroid Differentiation And Mutated Tp53, Nour Sabiha Naji, Sergiu Pasca, Theodora Chatzilygeroudi, Pablo Toledano-Sanz, Joseph Rimando, Yuju An, Yashvi Hemani, Brandy Perkins, Xinghan Zeng, Conover Talbot, Bogdan Paun, Abdulmuez Abdulmalik, Chen Lossos, Tatianna R Boronina, Ilias Sinanidis, Panagiotis Tsakiroglou, Priyanka Fernandes, Christopher Esteb, Alexander J Ambinder, Robert N Cole, Rena Xian, Ivana Gojo, Suman Paul, Mark J Levis, Amy E Dezern, Leo Luznik, Styliani Karanika, Linda S Resar, Richard J Jones, Frederick Bunz, Lukasz Gondek, Marios Arvanitis, Theodoros Karantanos Aug 2025

C-C Motif Chemokine Receptor-Like 2 Promotes The Interferon-Γ Signaling Response In Myeloid Neoplasms With Erythroid Differentiation And Mutated Tp53, Nour Sabiha Naji, Sergiu Pasca, Theodora Chatzilygeroudi, Pablo Toledano-Sanz, Joseph Rimando, Yuju An, Yashvi Hemani, Brandy Perkins, Xinghan Zeng, Conover Talbot, Bogdan Paun, Abdulmuez Abdulmalik, Chen Lossos, Tatianna R Boronina, Ilias Sinanidis, Panagiotis Tsakiroglou, Priyanka Fernandes, Christopher Esteb, Alexander J Ambinder, Robert N Cole, Rena Xian, Ivana Gojo, Suman Paul, Mark J Levis, Amy E Dezern, Leo Luznik, Styliani Karanika, Linda S Resar, Richard J Jones, Frederick Bunz, Lukasz Gondek, Marios Arvanitis, Theodoros Karantanos

Faculty, Staff and Students Publications

Patients with myeloid neoplasms with loss-of-function TP53 mutations and erythroid differentiation have poor outcomes, and a better understanding of disease biology is required. Upregulation of interferon-γ (IFN-γ) signaling has been associated with acute myeloid leukemia (AML) progression, selection of TP53 mutated clones and chemotherapy resistance, but its drivers remain unclear. In this study, we found that the surface receptor C-C motif chemokine receptor-like 2 (CCRL2) is overexpressed in AML with erythroid differentiation and TP53 mutations compared to other AML subtypes and healthy hematopoietic cells. CCRL2 knockout (KO) suppressed erythroleukemia growth in vitro and in vivo. Further proteomics and transcriptomics analysis …


Understanding The Why: Patient, Parent, And Oncologist Perspectives On Prognostic Communication Preferences In Advanced Childhood Cancer, Erin Batchelor, Rachel A Kentor, Calliope Reeves, Harmony Farner, Shoshana Mehler, Caroline Christianson, Erica C Kaye Aug 2025

Understanding The Why: Patient, Parent, And Oncologist Perspectives On Prognostic Communication Preferences In Advanced Childhood Cancer, Erin Batchelor, Rachel A Kentor, Calliope Reeves, Harmony Farner, Shoshana Mehler, Caroline Christianson, Erica C Kaye

Faculty, Staff and Students Publications

Background/objectives: High-quality prognostic communication in pediatric oncology is essential to support informed decision making, foster trust, and honor goals of care. While families differ in their preferences for how prognosis is discussed, clinicians often rely on assumptions rather than directly eliciting these preferences, risking misalignment and distress. To address this gap, we aimed to characterize patient, parent, and oncologist perspectives on key variables, experiences, and circumstances that influence their preferences for prognostic communication.

Methods: Semi-structured interviews were conducted with 85 participants (25 patients aged 12-25, 40 parents, and 20 oncologists) to elicit their preferences for prognostic communication and the reasons …


Time Ticks Slowly For Kidney Transplant Reform: Eskd Patient Challenges And Opportunities, Gregory P. Hess Aug 2025

Time Ticks Slowly For Kidney Transplant Reform: Eskd Patient Challenges And Opportunities, Gregory P. Hess

College of Population Health Faculty Papers

No abstract provided.


Sport Media Consumption In Ncaa Division І Fbs Subdivision: A Panel Regression Model Using X/Twitter, Seungbak Lee, Minsoo Kang, Wonson Lim, Ju-Pil Choe, Brennan K. Berg Aug 2025

Sport Media Consumption In Ncaa Division І Fbs Subdivision: A Panel Regression Model Using X/Twitter, Seungbak Lee, Minsoo Kang, Wonson Lim, Ju-Pil Choe, Brennan K. Berg

Journal of Issues in Intercollegiate Athletics

Athletic departments in collegiate sports have increasingly focused on enhancing sport consumer interest through social media. As social media usage continues to grow in college sports, understanding audience behavior on these platforms has become essential for athletic departments. This study examines the factors influencing consumer interest in Division I football teams’ X (formerly Twitter) accounts, utilizing a panel dataset comprising 18,221 team-day observations. Key determinants of changes in X followers were identified, including teams’ social media activity, on-field performance, scheduling events, and timing effects, with a focus on fan interest across temporal patterns such as month-to-month and day-to-day variations. The …


Peer-Led Sexual And Reproductive Healtheducation Programs At Universities, Madison Michelle Patrick Aug 2025

Peer-Led Sexual And Reproductive Healtheducation Programs At Universities, Madison Michelle Patrick

Silicon Valley Sociological Review

This applied research explores the accessibility, visibility, and comprehensiveness of sexual and reproductive health (SRH) education and services at universities, with a specific focus on contraceptive risk awareness. Recognizing college students as particularly vulnerable to misinformation regarding hormonal contraceptives, unintended pregnancy, and STI exposure, the study examines the role of university-provided SRH resources in mitigating these risks.

A mixed-methods content analysis was conducted on the SRH publicly-available web pages of four Northern California universities—Stanford University, San Francisco State University, Santa Clara University, and the University of California, Berkeley, chosen for their diversity in institutional identity. The research assessed each university’s …


Legislation, Racialization, And The Societal Issuessoutheast Asian Americans Face, Sydney Nguyen Aug 2025

Legislation, Racialization, And The Societal Issuessoutheast Asian Americans Face, Sydney Nguyen

Silicon Valley Sociological Review

This research proposal investigates the intersection of racialization and law in the Southeast Asian diaspora in the US at a time of rising anti-Asian hate crimes and marginalizing legislation. I propose a mixed-methods approach—integrating qualitative methods such as interviews and focus groups with quantitative surveys—to determine how racial formations and state policies contribute to the social and economic stratification of these groups. To contextualize these questions, I discuss how Asian Americans are underrepresented and miscategorized in criminal justice statistics, resulting in their ongoing marginalization and the masking of specific issues they face. This work aims to make a contribution to …


It's All Connected: The Emotional Triad In Nursing - Workplace Aggression, Burn-Out, And Resilience, Kerstin Hudgins Aug 2025

It's All Connected: The Emotional Triad In Nursing - Workplace Aggression, Burn-Out, And Resilience, Kerstin Hudgins

Creating Healthy Work Environments (CHWE)

For years, nursing has been dealing with the problems of unhealthy work environments. This session explores the phenomenon of interconnection between the various modalities to combat this issue and discusses prevention strategies. Toxicity will prevail unless we recognize the relationship between incivility, bullying, and other workplace aggressions. By identifying the root causes and making the connection between them, nurses will be able to manage this situation instead of treating these modalities as separate occurrences and issues. Just as nursing is no longer a profession that functions in a silo, we must also approach these issues as interconnected and not as …


An Early Review Of Generative Language Models In Automated Writing Evaluation: Advancements, Challenges, And Future Directions For Automated Essay Scoring And Feedback Generation, Yue Huang, Corey Palermo, Ruitao Liu, Yong He Aug 2025

An Early Review Of Generative Language Models In Automated Writing Evaluation: Advancements, Challenges, And Future Directions For Automated Essay Scoring And Feedback Generation, Yue Huang, Corey Palermo, Ruitao Liu, Yong He

Chinese/English Journal of Educational Measurement and Evaluation | 教育测量与评估双语期刊

Automated writing evaluation (AWE) has long supported assessment and instruction, yet existing systems struggle to capture deeper rhetorical and pedagogical aspects of student writing. Recent advances in generative language models (GLMs) such as GPT and Llama present new opportunities, but their effectiveness remains uncertain. This review synthesizes 29 studies on automated essay scoring and 14 on automated writing feedback generation, examining how GLMs are applied through prompting, fine-tuning, and adaptation. Findings show GLMs can approximate human scoring and deliver richer, rubric-aligned feedback, but fairness, validity, and ethical issues remain largely unaddressed. We conclude that GLMs hold promise to enhance AWE, …


Rna Sequencing-Based Transcriptome Analysis Of Liver In Laying Hens Supplemented With Dietary Probiotic Bacillus Species And Prebiotic Yeast (Saccharomyces Cerevisiae) Cell Walls, Ala E. Abudabos, Zafar M. Hakami, Ali R. Al Sulaiman, Riyadh S. Aljumaah, Valentino Palombo, Mashael R. Aljumaah, Mariasilvia D’Andrea, Abdulrahman S. Alharthi, Rashed A. Alhotan Aug 2025

Rna Sequencing-Based Transcriptome Analysis Of Liver In Laying Hens Supplemented With Dietary Probiotic Bacillus Species And Prebiotic Yeast (Saccharomyces Cerevisiae) Cell Walls, Ala E. Abudabos, Zafar M. Hakami, Ali R. Al Sulaiman, Riyadh S. Aljumaah, Valentino Palombo, Mashael R. Aljumaah, Mariasilvia D’Andrea, Abdulrahman S. Alharthi, Rashed A. Alhotan

Food and Animal Sciences Faculty Research

To investigate the impacts of dietary Bacillus-based probiotics and yeast-derived prebiotics on the hepatic transcriptome profile, 500 Hisex White laying hens were randomly allotted into five dietary treatments from 37 to 52 weeks of age: control; control + Bacillus subtilis; control + Bacillus subtilis and Bacillus licheniformis; control + Bacillus coagulans; and control + Saccharomyces cerevisiae yeast cell wall. Transcriptome analysis revealed a substantial number of differentially expressed genes exclusively between the control and prebiotic groups, identifying 2221 genes (FDR ≤ 0.05), with 980 genes upregulated (log2 fold change 0.69 to 24.62) and 1241 downregulated (log2 fold change −0.74 to …