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An Investigation Of Sex-Specific Effects Of Nucleus Accumbens Dopamine Receptor Signaling In Persistent Reward Seeking Under Punishment, Anna Caroline Toburen

Theses and Dissertations

Addiction involves persistent reward-seeking behavior despite adverse outcomes, with the nucleus accumbens (NAc) critically mediating motivation and cost-benefit decision-making. Dopamine (DA)-responsive neurons in the NAc, specifically D1 and D2 receptors within the NAc are crucial in encoding motivated behavior. However, the specific role of D1/D2 receptors in driving reward-seeking under punishment remains unclear. Preliminary findings suggest a sex-specific effect, with females exhibiting greater sensitivity to the suppressive effects of footshock on natural reward-seeking compared to males. We investigated the differential roles of NAc D1/D2 receptors in modulating reward-seeking behavior under punishment, with a focus on potential sex-specific effects. Using a …

Perspectives On Mathematical Modeling Education: Conceptions And Research, Geena Taite, Joseph Dinapoli

Department of Mathematics Faculty Scholarship and Creative Works

Mathematical modeling is a cyclical process in which mathematics is used to represent, explore, and better understand real-world situations by mathematizing a problem and validating the results. Unlike traditional word problems, modeling tasks require learners to make assumptions, define quantities, apply mathematics, interpret results, and revise solutions within authentic contexts. Mathematical modeling is increasingly recognized as essential in mathematics education, highlighted in standards such as the Common Core State Standards for Mathematics through mathematical practice 4 (MP4): model with mathematics. This entry explores the evolving landscape of mathematical modeling education. First, it reviews the diverse conceptions of modeling and the …

Human Adipose Stem Cell-Derived Small Extracellular Vesicles Modulate Glial Cell Response In Aged And Young Tbi Mouse Models, Salma S. Abdelmaboud

USF Tampa Graduate Theses and Dissertations

Traumatic brain injury (TBI) is a leading cause of long-term neurological impairment, with aging significantly increasing vulnerability and worsening outcomes. Older individuals experience greater cognitive and motor deficits after TBI and often show diminished responses to therapeutic interventions. Both aging and TBI independently promote heightened neuroinflammation and cognitive dysfunction, increasing susceptibility to poor recovery. This study investigated the therapeutic potential of small extracellular vesicles (sEVs) derived from human adipose-derived stem cells (hASCs) to promote neurological recovery and modulate neuroinflammation in a mouse model of TBI. Male C57BL/6 mice aged 3, 15, and 20 months underwent controlled cortical impact (CCI) and …

2025-09-04 Faculty Senate Newsletter, Morehead State University. Faculty Senate.

Faculty Senate Records

Faculty Senate newsletter from September 4, 2025.

Influences On Suicidality And Suicide-Prevention Needs For The Autistic Community: Qualitative Insights From Multiple Perspectives, Anne V. Kirby, Kristina Feldman, Wilhelm Clark, Amber N. Darlington, Alissa Atisme, Bobbi Duncan-Ishcomer, Rachel Kripke-Ludwig, Andrea Joyce, Whitney Lee, K. Rodriguez, Zack Siddeek, Kavitha Murthi, Brooks Keeshan, Hilary Coon, Christina Nicolaidis

School of Social Work Faculty Publications and Presentations

Autistic individuals are disproportionately likely to experience suicidal thoughts, feelings, and actions. Addressing suicidality is also a high priority of autistic community members. The goal of this study was to understand broad influences on suicidality and suicide-prevention needs for the autistic community. Using a community-based participatory research approach, we conducted a reflective thematic analysis of qualitative interviews with 16 autistic adults, 8 family members, and 14 mental health providers. Themes summarizing influences on suicidality and suicide-prevention needs centered on three broad thematic concepts: (1) Pervasive negative societal attitudes and social experiences have a lasting impact on autistic people's feelings of …

Climate Change-Related Threats To Railroads: Implications For Threat, Hazard And Risk Assessment, Frances L. Edwards, Daniel C. Goodrich

Faculty Research, Scholarly, and Creative Activity

Climate change has created new challenges for railroads around the world. The rail systems operate in open environments, subjecting them to increased heat, changing locations of heavy rains, developing sea level rise and storm surge, and a longer and stronger wildfire season. This research investigates how an updated threat and hazard identification and risk assessment (THIRA) can lead to the development of climate adaptation strategies that limit damage and disruption to the railroad enterprise. The THIRA analyzes which threats are of most concern in a specific rail segment, and which climate change adaptation strategies give a beneficial return on investment.

Preconditioning With Low-Dose Radiation Improves Antitumor Immunity And Survival In Dc-Vaccinated Mice, Eric Kwon, Shelby Namen, Colin J Willoughby, Solomon Kang, Gaurav Pandey, Alexander B Kim, Carl J Deselm

2020-Current year OA Pubs

Preconditioning regimens are essential for the immunologic success of cell therapies like CAR T cells. Nevertheless, their effect on cancer vaccines is underexplored, and preconditioning regimens are generally absent from cancer vaccine clinical trials. To address this knowledge gap, we evaluated the impact of various preconditioning strategies on dendritic cell (DC) vaccine efficacy in a murine tumor model. Mice bearing syngeneic tumors received preconditioning with 2 Gy low-dose radiation therapy (LD RT; whole-body or tumor-only), cyclophosphamide, paclitaxel, LD RT plus cyclophosphamide, or no preconditioning, followed by administration of antigen-loaded DCs. Whether whole-body or tumor-directed, LD RT preconditioning significantly enhanced vaccine-induced …

The Relationship Between The Hesi Integrated Exit Exam & Next Generation Nclex-Rn: Updated, Mamta Shah, Peter Granville, Ryan S. Baker, Michelle Bussard

International Nursing Research Congress (INRC)

Purpose
The purpose of this study was to determine the extent to which the HESI Integrated Exit Exams (E2) can predict nursing students’ first-time pass rates on the Next Generation NCLEX-RN (NGN-RN), expanding on findings reported by Shah et al (2024). Programs typically set a minimum score threshold of 850 or 900 on the E2 to consider students ready for the NCLEX (Olsen et al., 2022). We examined, "If students achieve a benchmark score on the E2, do they pass the NGN-RN on their first attempt?" Previous research has also examined the role of E2 policies and their association with …

Full Issue

Indian Journal of Law and Technology

No abstract provided.

Memf-Net: A Mega-Ensemble Of Multi-Feature Cnns For Classification Of Breast Histopathological Images, Alaa Hussein Abdulaal, Ali H. Abdulwahhab, Aqeel Majeed Breesam, Zahra Hasan Oleiwi, Riyam Ali Yassin, Morteza Valizadeh, Saja Nafea Mohsin

Iraqi Journal for Computer Science and Mathematics

Pathological anatomical images play a pivotal role in diagnosing diseases, notably breast cancer, which affects women globally. These images, obtained through biopsies or post-mortem examinations, are preserved to maintain their structural integrity. Software tools, like computer-aided diagnosis, aid doctors in early detection and treatment planning, contributing to reduced mortality rates. In this context, convolutional neural networks (CNNs) have emerged as valuable tools for diagnosing benign and malignant breast cancers. This paper introduces a Mega Ensemble Net method, leveraging multi-scale combination features on the breast histopathology dataset. Three fine-tuned deep learning models, namely ResNet-18, ResNet-34, and ResNet-50, are integrated into this …

Retracted: Capsule Network Model For Detecting Spoofing Attack In The Internet Of Medical Things (Iomt), Mohammad A. Alsharaiah, Mohammed Amin Almaiah, Mansour Obeidat, Rami Shehab

Iraqi Journal for Computer Science and Mathematics

The Internet of Medical Things (IoMT) has transformed healthcare delivery through real-time monitoring and data exchange. However, this integration of smart medical devices has also introduced critical cybersecurity threats, particularly spoofing attacks, which can compromise patient safety and system reliability. Conventional Intrusion Detection Systems (IDS) often fail to address IoMT-specific challenges such as class imbalance, computational constraints, and the need for real-time adaptability. This study proposes a Capsule Network (CapsNet)-based IDS that leverages spatial dependency modeling and hierarchical feature relationships to detect spoofing attacks in IoMT environments. Using the CICIoMT2024 dataset, we implemented a binary classification framework where spoofing instances …

Resilience, Elapsed Time Since Exposure To Workplace Violence, And Job Satisfaction Among Emergency Nurses In The United States, Ginny Glisson Ennis

Walden Dissertations and Doctoral Studies

The emergency nursing profession faces a critical challenge with a declining workforce and a high prevalence of workplace violence (WPV), which negatively impacts nurse job satisfaction. This quantitative study examined the relationships among nursing resilience, time elapsed since WPV exposure, and job satisfaction among emergency nurses (ENs) in the United States. Grounded in resilience and Herzberg’s two-factor theories, this study used a cross-sectional, correlational design. A national, anonymous online survey was distributed via social media, using a sharable QR code to recruit participants. The survey consisted of a total of 52 items, and collected demographic data, and time elapsed since …

The Parthenon, September 03, 2025, Baylee Parsons, Kaitlyn Fleming, Ashton Pack, Nate Harrah, Caden Adkins, Scott Price, Lilli Ross, Wade Sullivan

The Parthenon

No abstract provided.

Cecilia Clinkscale V. Commissioner Social Security

2025 Decisions

USDC for the Eastern District of Pennsylvania

Bartók’S Romanian Folk Dances: A Consideration Of Sound And Movement, Bailey Frame

Theses and Dissertations

Béla Bartók (1881-1945) cared deeply about authenticity in his work. He continually passed by derivative versions, and instead sought the oldest, earliest, most inaugural version of each folk tune to use as that launching point for his compositions. As he collected the Transylvanian folk tunes that would become his Romanian Folk Dances, he disregarded inconveniences like bad weather and exhausting travel, and he doggedly lugged with him a newly invented Edison phonograph. Though it was unwieldy and fickle, the device allowed him to capture folk music in the moment it was created. Not one for sterile auditoriums or music studios, …

Fs Transcript 2025-09-03, Northern Illinois University

Faculty Senate Archives

No abstract provided.

State Of Illinois Model Programs Of Study Guides: 2025 Utilization Report, Meagan Mitchell Phd

Reports, Analyses, and other Publications

The State of Illinois Model Programs of Study Guides were developed in collaboration with the Illinois State Board of Education (ISBE) and Illinois Community College Board (ICCB) through a process led and facilitated by Education Systems Center (EdSystems) at Northern Illinois University. The process included extensive research into labor market information and credential programs, as well as dialogue across secondary, postsecondary, and employer stakeholders. With the support of ICCB, EdSystems researched the utilization of the State of Illinois Model Programs of Study Guides: Culinary and Hospitality and Human and Public Service.

We consulted with ICCB to receive the Perkins V …

Commonwealth Times 2025-09-03

Commonwealth Times, 1969-

No abstract provided.

September 3, 2025 General Faculty Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Writing Workshop In Prose, Kylee C. Pastore

Open Educational Resources

The Prose Workshop (Fall 2025) is a zero-textbook-cost (ZTC) course at The City College of New York that integrates open educational resources (OER) to develop students’ skills as writers, readers, and critics. Structured in two major parts, the course begins with cultural criticism, guiding students to produce a polished 750–1000 word essay that combines close observation, analysis, and creative voice. The second half focuses on longform narrative nonfiction, culminating in a 3,000-word editorial essay intended for submission to a real-world publication. Alongside these core projects, students engage in weekly homework blogs, annotated course readers, and a final creative experiment in …

Modeling Of Urea Drying And Granulation Process In Fluidized Bed, Jalolitdin Pakhritdinovich Mukhitdinov, Aleksey Viktorovich Schulz

Chemical Technology, Control and Management

This article is devoted to the mathematical modeling of urea drying and granulation processes in a fluidized bed. A brief description is provided for the functional blocks included in the mathematical model, along with the required parameters that form an integrated representation of the technological process. The SR-POLAR model is used to describe a phase equilibrium between the components involved. The interconnections between functional blocks are shown in the process flow diagram. Block diagrams for modeling a multi-chamber granulation unit and the cooling system for the resulting granules are presented. Granule growth in the fluidized bed is described using a …

Increasing The Robustness Of A Control System For A Complex Dynamic Plant By Correcting Nonlinearity In The Warping Process, Tukhtamurod Khayitmurodovich Avezov, Zokhid Ergashboyevich Iskandarov

Chemical Technology, Control and Management

The paper discusses the challenges of enhancing the robustness of a control system for a complex dynamic plant by addressing nonlinearity in the warping process. Devices that ensure the stability of the control system against parameter non-stationarity on the warping machine are referred to as state controllers. The operating principle of these devices relies on providing artificial nonlinearity to the rear connection circuit of the control system's actuator. However, this nonlinearity is implemented using components that consider the parameters of low control quality. Therefore, it is necessary to continuously adjust the nonlinearity parameters to, on one hand, reduce the load …

Optimizing Beer Fermentation Through Intelligent Control, Azizbek Nodirbekovich Yusupbekov, Mirjalol Yusupov

Chemical Technology, Control and Management

This paper presents an intelligent control approach for optimizing the beer fermentation process using fuzzy logic and adaptive neuro-fuzzy inference systems. By incorporating multivariable inputs—temperature error and pH deviation—the proposed system effectively handles the nonlinear dynamics and biological variability inherent in fermentation. Simulation results demonstrate improved control accuracy, responsiveness, and robustness compared to conventional methods, making the approach suitable for integration in modern brewery automation systems.

Faculty Senate Meeting, 60th Senate Recording (9/3/2025), Csusb Faculty Senate

CSUSB Faculty Senate records

No abstract provided.

Intronic Fgf14 Gaa Repeat Expansions Impact Progression And Survival In Multiple System Atrophy., Viorica Chelban, David Pellerin, Nirosen Vijiaratnam, Hamin Lee, Yen Yee Goh, Lauren Brown, Sara Sambin, Danielle Seilhean, Stephane Lehericy, Pablo Iruzubieta, Rahema Mohammad, Eleanor Self, Annarita Scardamaglia, Cameron Lee, Miriama Ostrozovicova, Marie-Josée Dicaire, Christine Girges, Emil K. Gustavsson, David Murphy, Toby Curless, Joshua Laß, Joanne Trinh, Timothy Rittman, James B. Rowe, Marios Hadjivassiliou, Neil Archibald, Matt C. Danzi, Catherine Ashton, Virginie Roth, Marion Wandzel, Warren A. Cheung, Djordje O. Gveric, Bart De Vil, Jordan Follett, P Nigel Leigh, Lukas Beichert, Tomi Pastinen, Céline Bonnet, Mathilde Renaud, Wassilios G. Meissner, Anne Sieben, David Crosiers, Patrick Cras, Stephan Zuchner, Jean-Christophe Corvol, Matthew J. Farrer, Matthis Synofzik, Bernard Brais, Tom Warner, Huw R. Morris, Zane Jaunmuktane, Tom Foltynie, Henry Houlden

Manuscripts, Articles, Book Chapters and Other Papers

Partial phenotypic overlap has been suggested between multiple system atrophy and spinocerebellar ataxia 27B, the autosomal dominant ataxia caused by an intronic GAA•TTC repeat expansion in FGF14. In this study, we investigated the frequency of FGF14 GAA•TTC repeat expansion in clinically diagnosed and pathologically confirmed multiple system atrophy cases. We screened 657 multiple system atrophy cases (193 clinically diagnosed and 464 pathologically confirmed) and 1003 controls. The FGF14 repeat locus was genotyped using long-range PCR and bidirectional repeat-primed PCRs, and expansions were confirmed with targeted long-read Oxford Nanopore Technologies sequencing. We identified 19 multiple system atrophy cases carrying an FGF14 …

Investigating Bacterial Vaginosis Pathogenesis Using Peptide Nucleic Acid-Fluorescence In Situ Hybridization With A Focus On The Roles Of Gardnerella Species, Prevotella Bivia, And Fannyhessea Vaginae, Sheridan D. George, Megan H. Amerson-Brown, Lúcia G.V. Sousa, Tyler M. Carter, Alexa H. Rinehart, Ashleigh N. Riegler, Sixto M. Leal, Kristal J. Aaron, Jiaying Hao, Ashutosh Tamhane, Chaoling Dong, John W. Lammons, Jacob H. Elnaggar, Keonte J. Graves, Paweł Łaniewski, Melissa M. Herbst-Kralovetz, Christopher M. Taylor, Nuno Cerca, Christina A. Muzny

School of Graduate Studies Faculty Publications

Background. Bacterial vaginosis (BV) is a vaginal dysbiosis characterized by polymicrobial communities of BV-associated bacteria (BVAB) adhered to the vaginal epithelium. Despite decades of research, its etiology remains unknown. We aimed to investigate BV biofilm formation over time among women who developed incident BV (iBV) using peptide nucleic acid-fluorescence in situ hybridization (PNA-FISH), focusing on 3 key BVAB (Gardnerella species, Prevotella bivia, and Fannyhessea vaginae). Methods. Heterosexual, nonpregnant women ages 18–45 with optimal vaginal microbiota were enrolled to self-collect twice-daily vaginal specimens for 60 days. iBV was defined as a Nugent score of 7–10 on ≥ 4 consecutive specimens. For …

Documents From The September 3, 2025 Meeting Of The Associated Students Of The University Of Montana (Asum), Associated Students Of University Of Montana, Kate Austin Payne

Senate Meeting Agendas and Minutes, 2007-Present

Agenda and meeting minutes from the September 3, 2025 meeting of the Associated Students of the University of Montana (ASUM).

Lindenwood Digest, September 3, 2025, Lindenwood University

Lindenwood Digest

The Lindenwood Digest has been a digital employee newsletter since 2009.

Genome-Wide Association Study And Genomic Prediction Of Leaf Spot (Stemphylium Vesicarium) Resistance In Spinach Diversity Panel, Gehendra Bhattarai, Bo Liu, James Cor, Ainong Shi

Horticulture Faculty Publications and Presentations

Stemphylium leaf spot (SLP), caused by Stemphylium vesicarium, has emerged as an increasing threat to spinach production in the United States, with widespread outbreaks reported across major spinach-growing regions over the past two decades. The objectives of this study were to: (1) evaluate global USDA spinach germplasm collections and commercial cultivars for resistance to S. vesicarium; (2) perform genome-wide association studies (GWAS) to identify genomic regions associated with resistance; and (3) conduct genomic prediction (GP) to enhance selection accuracy. A total of 311 diverse spinach genotypes, including USDA germplasm accessions and commercial cultivars, were evaluated under greenhouse conditions at the …

A Comprehensive Framework For Assessing Terrestrial Analogue Field Sites For Ocean Worlds, Jennifer C. Stern, Heather V. Graham, Bradley Burcar, Emily S. Martin, Aaron Noell, Kevin Hand, Jeff S. Bowman, Peter Doran, Virginia Edgcomb, James F. Holden, Alta E.G. Howells, Michael J. Malaska, Brook L. Nunn, Jani Radebaugh, Laura E. Rodriguez, Schuyler Borges, Dina Bower, Samuel Courville, Melisa Diaz, Benjamin Hockman, Julie Huber, Justin Lawrence, Trista Vick-Majors, Conor A. Nixon, John R. Spear, Amanda V. Steckel, Anezina Solomonidou, Nicholas Schmerr, Britney Schmidt, Matthew O. Schrenk, Lauren Seyler

Michigan Tech Publications

Field studies at terrestrial analogue sites represent an important contribution to the science of ocean worlds. The value of the science and technology investigations conducted at field analogue sites depends on the relevance of the analogue environment to the target ocean world. We accept that there are no perfect analogues for many of the unique environments represented by ocean worlds but suggest that a one-to-one matching of environmental characteristics and conditions is not crucial to the success or impact of the work. Instead, we must determine which processes and parameters are required to map directly to the target ocean world …