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Impact Of Cardiac Rehabilitation Including Deep Breathing On Endurance Level In Patients With Mild Heart Failure, Shehab Mahmoud Salwa R. El-Gendy, Shehab Abd El-Kader, Mahmoud Abd E-Kader, Afnan M. Alkhateeb, Saad S. Alfawaz, Ziyad A. Neamatallah, Umar M. Alabasi, Riziq Allah Mustafa Gaowgzeh, Mohamed F. El- Banna, Tamer M. El-Saeed, Heba Embaby, Rasha M. Hegazy, Ahmed M. Aboeleneen Sep 2025

Impact Of Cardiac Rehabilitation Including Deep Breathing On Endurance Level In Patients With Mild Heart Failure, Shehab Mahmoud Salwa R. El-Gendy, Shehab Abd El-Kader, Mahmoud Abd E-Kader, Afnan M. Alkhateeb, Saad S. Alfawaz, Ziyad A. Neamatallah, Umar M. Alabasi, Riziq Allah Mustafa Gaowgzeh, Mohamed F. El- Banna, Tamer M. El-Saeed, Heba Embaby, Rasha M. Hegazy, Ahmed M. Aboeleneen

Journal of Medical Rehabilitation Science

Background: Heart failure (HF) is a morbid illness with high mortality rate. Patients with HF necessitate a cardiac rehabilitation (CR) that is a planned, lasting care, which is highly cost effective in lowering hospital admission and improving quality of life. Objective: The aim of the study was to compare the effects of diaphragmatic breathing and incentive spirometer on endurance level in patients with mild heart failure. Methods: An experimental study, single-blinded design. Forty-five patients (25 males and 20 females) diagnosed with mild HF were nominated from the cardiac unit in king Abdulaziz University Hospital, Jeddah, KSA. Age range was 45-75, …


The Validity And Reliability Of Box And Blocks Test On Children With Traumatic Elbow Injury, Mohammad Tamboosi, Mohammad Tamboosi, Sara Tamboosi, Abdulraouf Fasihaldeen, Jana Bashraheel, Moaaz Alnajjar, Raghad Melibary, Yazeed Bamehriz Sep 2025

The Validity And Reliability Of Box And Blocks Test On Children With Traumatic Elbow Injury, Mohammad Tamboosi, Mohammad Tamboosi, Sara Tamboosi, Abdulraouf Fasihaldeen, Jana Bashraheel, Moaaz Alnajjar, Raghad Melibary, Yazeed Bamehriz

Journal of Medical Rehabilitation Science

INTRODUCTION: The Box and Blocks Test (BBT) is a widely used measure of manual dexterity, but its validity and reliability as an outcome measure for upper extremity function in children with Traumatic Elbow Injuries (TEI) require further investigation. This study aimed to evaluate the BBT's test-retest reliability, sensitivity to functional change (construct validity), and discriminative validity in this specific pediatric population. METHOD: Twenty-nine children (75.9% male; age range: 6-16 years) with TEI participated in a prospective study. BBT scores for both hands were assessed pre- and post- an eight-week physiotherapy intervention. Test-retest reliability was evaluated via Cronbach's Alpha, and discriminative …


Too Scared To Use: Living Wills And Orderly Liquidation Of Too-Big-To-Fail Financial Institutions, Jeffery Y. Zhang Sep 2025

Too Scared To Use: Living Wills And Orderly Liquidation Of Too-Big-To-Fail Financial Institutions, Jeffery Y. Zhang

Law & Economics Working Papers

The term “too big to fail” became ubiquitous following the 2007-2008 Global Financial Crisis. Lawmakers, regulators, and scholars wondered if there was a better way forward than issuing an array of ad hoc bailout packages to large financial institutions. Congress, in enacting the Dodd-Frank Act, sought to address the concern by creating a new regulatory framework to resolve large financial institutions in an orderly manner.

First, Congress required too-big-to-fail institutions to file “living wills,” essentially planning documents that describe the institution’s path to a safe failure under the Bankruptcy Code—a failure that would not impact system-wide financial stability. Second, Congress …


Interindividual Genetic Differences Drive Discordance Between Serum Calcidiol And Calcitriol Concentrations In Females., Elizabeth K Hutchins, Changran Niu, Jing Xue, Debin Wan, Carolina V Campos, Molly Warren, Megan M Knuth, Michael B Whalen, Venkata S Voruganti, Rafiou Agoro, James C Fleet, Bruce D Hammock, Folami Ideraabdullah Sep 2025

Interindividual Genetic Differences Drive Discordance Between Serum Calcidiol And Calcitriol Concentrations In Females., Elizabeth K Hutchins, Changran Niu, Jing Xue, Debin Wan, Carolina V Campos, Molly Warren, Megan M Knuth, Michael B Whalen, Venkata S Voruganti, Rafiou Agoro, James C Fleet, Bruce D Hammock, Folami Ideraabdullah

Faculty Research 2025

Vitamin D insufficiency (VDI) is primarily determined by serum levels of calcidiol, which serves as a biomarker for the less abundant but most potent bioactive metabolite, calcitriol. However, population studies often show discordance between calcidiol and calcitriol. Here, a genetically diverse population of 7 inbred mouse strains was used to investigate the role of interindividual genetic differences in driving calcidiol-to-calcitriol discordance under vitamin D sufficient (VDS) vs depleted (VDD) conditions. We found high interstrain variability in calcitriol that was discordant with calcidiol under VDS and VDD conditions. However, under VDS conditions, stratification by calcitriol level revealed that strains with serum …


A Polar Turbulence Invariant Map With Applicability To Realisable Machine Learning Turbulence Models, James G. Wnek, Christopher Schrock, Eric M. Wolf, Mitch Wolff Sep 2025

A Polar Turbulence Invariant Map With Applicability To Realisable Machine Learning Turbulence Models, James G. Wnek, Christopher Schrock, Eric M. Wolf, Mitch Wolff

Mechanical and Materials Engineering Faculty Publications

Invariant maps are a useful tool for turbulence modelling, and the rapid growth of machine learning-based turbulence modelling research has led to renewed interest in them. They allow different turbulent states to be visualised in an interpretable manner and provide a mathematical framework to analyse or enforce realisability. Current invariant maps, however, are limited in machine learning models by the need for costly coordinate transformations and eigendecomposition at each point in the flow field. This paper introduces a new polar invariant map based on an angle that parametrises the relationship of the principal anisotropic stresses, and a scalar that describes …


High Energy Consumption Characterizes Abnormal Brain State Transitions In Temporal Lobe Epilepsy, Sam S. Javidi, Qirui Zhang, Ankeeta Ankeeta, Michael R. Sperling, Joseph I. Tracy Sep 2025

High Energy Consumption Characterizes Abnormal Brain State Transitions In Temporal Lobe Epilepsy, Sam S. Javidi, Qirui Zhang, Ankeeta Ankeeta, Michael R. Sperling, Joseph I. Tracy

Farber Institute for Neuroscience Faculty Papers

Temporal lobe epilepsy (TLE) patients experience shifts between non-seizing and seizing brain states, but the structural networks underlying these transitions remain undefined and poorly characterized. We detected dynamic brain states in resting-state fMRI and constructed linked structural networks utilizing multi-shell diffusion-weighted MR data. Leveraging network control theory, we interrogated the structural data for all possible brain state transitions, identifying those requiring abnormal levels of transition energy (low or high) in TLE compared to matched healthy participants (n's = 25). Results revealed three transitions requiring significantly higher energy in TLE; no abnormally low-energy transitions were observed. In HPs, transitions relied on …


Season 2 Episode 5: Quitting Ain't Easy, Sara Gras Sep 2025

Season 2 Episode 5: Quitting Ain't Easy, Sara Gras

Season 02

Where there is gambling, there are addicted gamblers. Gambling addiction is more than just an economic problem – it can have a profoundly serious impact on the lives of individuals who are affected – but the research on, and funding for treatment of, compulsive gambling is only a fraction of what is available for substance use disorders. The rapid growth of sports betting has created a new challenge in this space, impacting a new demographic of young men. This episode provides some foundational information about gambling addiction and recovery as a foundation for a discussion of responsible gaming and industry …


Relaxation Of The Leaf Economics Spectrum Within And Across Quaking Aspen Populus Tremuloides Genotypes, Jolanta Rieksta, Bente J. Graae, Kenny Helsen, Rozália E. Kapás, Richard Strimbeck, Benjamin W. Blonder Sep 2025

Relaxation Of The Leaf Economics Spectrum Within And Across Quaking Aspen Populus Tremuloides Genotypes, Jolanta Rieksta, Bente J. Graae, Kenny Helsen, Rozália E. Kapás, Richard Strimbeck, Benjamin W. Blonder

Aspen Bibliography

Plant functional traits typically show strong covariation, e.g. as in the worldwide leaf economics spectrum (LES). Covariation is thought to arise from selective forces and physical constraints. However, processes shaping covariation at interspecific scales may differ from those at intraspecific scales. Potential sources of intraspecific trait variation include variation in genetics, abiotic environment, and biotic environment; any of these factors may cause divergence from interspecific patterns. Quaking aspen, Populus tremuloides (Salicaceae), is a widespread tree species ideal for assessing these processes' role in the intraspecific LES, due to its clonal growth along environmental gradients, intraspecific variation in cytotype (ploidy level), …


Overview Of A Hospital Management Information System Using The Hot-Fit Method In Medan Hospitals In 2025, Grace Putri Laia, Hotmarina Lumban Gaol, Jev Boris Sep 2025

Overview Of A Hospital Management Information System Using The Hot-Fit Method In Medan Hospitals In 2025, Grace Putri Laia, Hotmarina Lumban Gaol, Jev Boris

Journal of Indonesian Health Policy and Administration

Hospital Management Information System (SIMRS/HMIS) is crucial in ensuring efficiency and quality in hospital services by integrating clinical and administrative functions. This study aims to evaluate the implementation of HMIS at Medan Adventist Hospital in 2025 using the Human-Organization-Technology Fit (HOT-Fit) framework. A descriptive design with total sampling was employed, involving 70 respondents comprising medical records staff, inpatient and outpatient registration staff, and ward officers. Data were collected through a structured questionnaire adapted from a validated instrument (validity 0.690–0.900; reliability 0.841–0.911) and analyzed using descriptive statistics. The results showed a high level of implementation in all HOT-Fit domains: system use …


‘Not The Usual Gig’: The Personal Scope(S) Of Application Of Directive 2024/2831 On Improving Working Conditions In Platform Work, Nicola Countouris, Valerio De Stefano Sep 2025

‘Not The Usual Gig’: The Personal Scope(S) Of Application Of Directive 2024/2831 On Improving Working Conditions In Platform Work, Nicola Countouris, Valerio De Stefano

Articles & Book Chapters

This article examines the complex and innovative personal scope of the EU Platform Work Directive 2024/2831, highlighting its dual framing around the concepts of ‘platform workers’ and the broader category of ‘persons performing platform work’. The authors explore how the Directive partially departs from traditional binary distinctions between employees and self-employed persons by introducing a more nuanced regulatory approach anchored in both labour law and data protection law. The article analyses the scope of key provisions of the Directive, showing how it confers many protections beyond the confines of the employment relationship. It critically evaluates the potential interpretive tensions between …


Prosecutor Transparency Project: Racial Disparities Study (Washtenaw County, Michigan), Grady Bridges, J. J. Prescott Sep 2025

Prosecutor Transparency Project: Racial Disparities Study (Washtenaw County, Michigan), Grady Bridges, J. J. Prescott

Law & Economics Working Papers

This report investigates and estimates racial disparities in prosecutorial decision-making in the Washtenaw County Prosecutor’s Office (WCPO) from 2017 to 2022. The analysis relies on currently available data resources at the WCPO and examines decision-making at four different junctures in the prosecutorial process: 1) case approval (i.e., warrant authorization) and charge selection, 2) habitual-offender designation (under Michigan law), 3) plea bargaining, and 4) diversion and deferral opportunities. Racial disparities appear most visibly at the earliest stages of the criminal justice process, with People of Color substantially overrepresented in the warrant requests the WCPO receives from law enforcement. The data further …


Mcsa Forum Minutes 09/08/2025, Morris Campus Student Association Sep 2025

Mcsa Forum Minutes 09/08/2025, Morris Campus Student Association

Morris Campus Student Association

No abstract provided.


The Jokowi Effect On The Victory Of Prabowo: Do People Vote For Continuity?, Cakra Yudi Putra, Dyah Ayu Febriani, Andri Tantyo Cahyo Nugroho, Teguh Dartanto Sep 2025

The Jokowi Effect On The Victory Of Prabowo: Do People Vote For Continuity?, Cakra Yudi Putra, Dyah Ayu Febriani, Andri Tantyo Cahyo Nugroho, Teguh Dartanto

Economics and Finance in Indonesia

The 2024 Indonesian presidential election marked a striking realignment as Prabowo Subianto—a former opposition leader—secured victory with the tacit endorsement of outgoing President Joko Widodo (Jokowi). This study investigates how the enduring popularity and policy achievements of Jokowi shaped voter preferences in favor of Prabowo, effectively positioning the election as a referendum on political continuity. Building on theories of economic voting and retrospective performance evaluation, the analysis explores the impact of district-level economic indicators, social media penetration, ideological orientation, social assistance distribution, and sociocultural characteristics on electoral outcomes. Employing Ordinary Least Squares (OLS) regression on data from 481 administrative regions, …


The Basics Of The Mundlak And Chamberlain Projections, Badi H. Baltagi, Tom Wansbeek Sep 2025

The Basics Of The Mundlak And Chamberlain Projections, Badi H. Baltagi, Tom Wansbeek

Center for Policy Research

One of the best-known results in panel data econometrics, due to Mundlak (1978), is the equality of the random-effects and fixed-effects estimators when the individual effects are correlated with the means over time of the regressors. Chamberlain (1980) showed that the same result holds when the individual effects are correlated with the regressors for all moments in time separately. In this chapter, we review basic elements of the Mundlak and Chamberlain projections. We emphasize the simplicity that is often obtained when the model is transformed into the within and between-model, following Arellano (1993). Topics that we discuss include the augmented …


Board Of Directors Meeting Minutes (September 8, 2025), File 1, Dmacc Sep 2025

Board Of Directors Meeting Minutes (September 8, 2025), File 1, Dmacc

Board of Directors Meeting Minutes

This file contains the minutes from the Des Moines Area Community College Board meeting held on September 8, 2025.


Detecting Electrical Submersible Pump (Esp) Failures And Estimating Run Life Using Artificial Neural Networks, Mostafa Ahmed Sobhy Sep 2025

Detecting Electrical Submersible Pump (Esp) Failures And Estimating Run Life Using Artificial Neural Networks, Mostafa Ahmed Sobhy

Theses and Dissertations

Electric Submersible Pumps (ESPs) are one of the important artificial lift methods for sustaining production in mature and high-water-cut wells; but may suffer frequent failures due to mechanical, electrical, hydraulic, chemical, and operational failures. These failures can yield substantial deferred production and intervention costs. Plenty of ESP installations are fitted with downhole sensors. Yet, it is observed that the current industry practice underutilizes the wealth of available sensor and operational data and lacks standardized, explainable failure-type identification and classification.

In this thesis, a comprehensive Machine Learning (ML) and Deep Learning (DL) framework was introduced for ESPs that simultaneously estimates remaining …


Third Amended Plan Non-Monetary Terms Sep 2025

Third Amended Plan Non-Monetary Terms

Catholic Dioceses in Bankruptcy

No abstract provided.


Budget Recommendations Fy2026-2027, Tennessee. Commission On Children And Youth. Sep 2025

Budget Recommendations Fy2026-2027, Tennessee. Commission On Children And Youth.

Annual Report

No abstract provided.


Tracing Carceral Continuities: A Review Of Recent Works On The Incarcerations Of The "Bhima Koregaon-16", Saumya Dadoo, Shailza Sharma Sep 2025

Tracing Carceral Continuities: A Review Of Recent Works On The Incarcerations Of The "Bhima Koregaon-16", Saumya Dadoo, Shailza Sharma

Socio-Legal Review

This systematic review analyses three recent books that focus on the incarceration of the “BK-16”—sixteen activists who were detained in the aftermath of a 2018 gathering to celebrate the bicentenary of the Battle of Koregaon: (1) Suchitra Vijayan and Francesca Recchia’s How Long Can the Moon Be Caged (Pluto Press 2023); (2) Alpa Shah’s The Incarcerations: Bhima Koregaon and the Search for Democracy in India (Harper Collins India 2024); and (3) Sudha Bharadwaj’s From Phansi Yard: My Year with the Women of Yerawada (Juggernaut 2023). The authors argue that, read together, the three works help situate the political and legal …


Staff Education To Implement The Phq-9 For Depression Screening, Lydia Emuobosa Opara Sep 2025

Staff Education To Implement The Phq-9 For Depression Screening, Lydia Emuobosa Opara

Walden Dissertations and Doctoral Studies

Depression is common yet frequently underdiagnosed in group home settings serving adult and geriatric residents. This Doctor of Nursing Practice (DNP) project aimed to improve staff knowledge and promote routine use of the Patient Health Questionnaire-9 (PHQ-9), a validated depression screening tool, through an evidence-based educational intervention. A practice gap was identified at the project site due to inconsistent use and documentation of the PHQ-9, primarily linked to staff knowledge deficits. The project explored whether educating staff on PHQ-9 administration, scoring, and documentation would lead to improved knowledge, as measured by pre- and post-intervention assessments. Guided by the ADDIE instructional …


Cyclical Matters: Black Labor, Temporality, And The Incomplete Reconstructions Within African American Literature, Courtney Walton Sep 2025

Cyclical Matters: Black Labor, Temporality, And The Incomplete Reconstructions Within African American Literature, Courtney Walton

Dissertations

This dissertation examines the role literature plays in understanding black life post-reconstruction and post-civil rights movement. Specifically, I explore the continuation of injustices and mistreatment for black workers, the role black labor plays during the first and second post-reconstructions, and how literature can be used in framing this discussion. The similarities between these periods help us to better understand the cycle of racist societal expectations and the challenges black workers face integrating into society, discriminatory mandates required of black workers, the unfair job market, and forced labor. These periods interact cyclically in that the second post-reconstruction models the first post-reconstruction. …


Give People Money: The Effect Of Perceived Inequality In Everyday Life And Previous Cash-Transfer Programs On Support For Universal Basic Income, David Thomas Igliozzi Sep 2025

Give People Money: The Effect Of Perceived Inequality In Everyday Life And Previous Cash-Transfer Programs On Support For Universal Basic Income, David Thomas Igliozzi

Dissertations

Economic inequality is a global concern with many adverse consequences for people across class divides. These consequences vary in scope—from negative effects on individual’s physical, mental, and social health to large-scale economic shifts which result from climate change (Galbraith & Hale, 2008; Hiesh & Pugh, 1993; Kaplan et al., 1996; La Ferrara & Alesina, 2000; Solt, 2008; Vilhjalmsdottir et al., 2016; Wilkinson & Pickett, 2007). Policy solutions meant to address the negative effects of economic inequality include government redistribution of wealth. Universal Basic Income (UBI), a specific and actionable policy of government redistribution, is a promising method of economic inequality …


“The Wonderful Swiftness Of The Soul”: Mental Movement And Religious Ethics In Medieval English Literature, Abigail Palmisano Sep 2025

“The Wonderful Swiftness Of The Soul”: Mental Movement And Religious Ethics In Medieval English Literature, Abigail Palmisano

Dissertations

This dissertation analyzes conceptual metaphors of psychological motion and stability in medieval English religious literature. I trace how language itself structures cultural approaches to epistemology, spiritual knowing, and virtue. Chapter One examines Alfred’s translation of Neoplatonic metaphors of psychological movement in the OE translations of The Consolation of Philosophy and Augustine’s Soliloquies. I argue that the reconfiguration of these metaphors into images of stability reveals an epistemology centered on certainty. Chapter Two compares the omission of motive psychological metaphor in Cynewulf’s Juliana and Ælfric’s “St. Agatha and St. Lucy” in process of translation. While Cynewulf’s depiction of virtue through stability …


2025-10-08 As Misinformation Rises, Can Students Believe What They See?, Julia Pilch Sep 2025

2025-10-08 As Misinformation Rises, Can Students Believe What They See?, Julia Pilch

The Spectator Online

No abstract provided.


Increased Risk Of Postoperative Complications In Patients With Hypertension Undergoing Mohs Micrographic Surgery, Alexandra Elder, Henry Yang, Megan O'Donnell-Capelli, Jenna Mandel, Molly Wallace, Lauren Banner, Ramsay Hafer, Thomas Rohan, Neda Nikbakht Sep 2025

Increased Risk Of Postoperative Complications In Patients With Hypertension Undergoing Mohs Micrographic Surgery, Alexandra Elder, Henry Yang, Megan O'Donnell-Capelli, Jenna Mandel, Molly Wallace, Lauren Banner, Ramsay Hafer, Thomas Rohan, Neda Nikbakht

Department of Dermatology and Cutaneous Biology Faculty Papers

Hypertension has been previously associated with higher intraoperative bleeding risk in patients undergoing Mohs micrographic surgery. However, the risks of common postoperative Mohs micrographic surgery complications have not been substantiated by large studies. Our study aimed to assess the risks of common Mohs micrographic surgery complications for patients with hypertension utilizing the TriNetX database, a global health records database encompassing over 105 million patients' data, from January 2009 to January 2024. After 1:1 propensity score matching for age, sex, race, diabetes, nicotine dependence, obesity, and anticoagulant use, the final analysis included 80,739 patients in each cohort of patients with hypertension …


Author Correction: Functional Mechanisms Underlying Pleiotropic Risk Alleles At The 19p131 Breast-Ovarian Cancer Susceptibility Locus, Kate Lawrenson, Siddhartha Kar, Karen Mccue, Karoline Kuchenbaeker, Kyriaki Michailidou, Jonathan Tyrer, Jonathan Beesley, Susan J Ramus, Qiyuan Li, Melissa K Delgado, Janet M Lee, Kristiina Aittomäki, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Banu K Arun, Brita Arver, Elisa V Bandera, Monica Barile, Rosa B Barkardottir, Daniel Barrowdale, Matthias W Beckmann, Javier Benitez, Andrew Berchuck, Maria Bisogna, Line Bjorge, Carl Blomqvist, William Blot, Natalia Bogdanova, Anders Bojesen, Stig E Bojesen, Manjeet K Bolla, Bernardo Bonanni, Anne-Lise Børresen-Dale, Hiltrud Brauch, Paul Brennan, Hermann Brenner, Fiona Bruinsma, Joan Brunet, Shaik Ahmad Buhari, Barbara Burwinkel, Ralf Butzow, Saundra S Buys, Qiuyin Cai, Trinidad Caldes, Ian Campbell, Rikki Cannioto, Jenny Chang-Claude, Jocelyne Chiquette, Ji-Yeob Choi, Kathleen B M Claes, Linda S Cook, Angela Cox, Daniel W Cramer, Simon S Cross, Cezary Cybulski, Kamila Czene, Mary B Daly, Francesca Damiola, Agnieszka Dansonka-Mieszkowska, Hatef Darabi, Joe Dennis, Peter Devilee, Orland Diez, Jennifer A Doherty, Susan M Domchek, Cecilia M Dorfling, Thilo Dörk, Martine Dumont, Hans Ehrencrona, Bent Ejlertsen, Steve Ellis, Christoph Engel, Eunjung Lee, D Gareth Evans, Peter A Fasching, Lidia Feliubadalo, Jonine Figueroa, Dieter Flesch-Janys, Olivia Fletcher, Henrik Flyger, Lenka Foretova, Florentia Fostira, William D Foulkes, Brooke L Fridley, Eitan Friedman, Debra Frost, Gaetana Gambino, Patricia A Ganz, Judy Garber, Montserrat García-Closas, Aleksandra Gentry-Maharaj, Maya Ghoussaini, Graham G Giles, Rosalind Glasspool, Andrew K Godwin, Mark S Goldberg, David E Goldgar, Anna González-Neira, Ellen L Goode, Marc T Goodman, Mark H Greene, Jacek Gronwald, Pascal Guénel, Christopher A Haiman, Per Hall, Emily Hallberg, Ute Hamann, Thomas V O Hansen, Patricia A Harrington, Mikael Hartman, Norhashimah Hassan, Sue Healey, Florian Heitz, Josef Herzog, Estrid Høgdall, Claus K Høgdall, Frans B L Hogervorst, Antoinette Hollestelle, John L Hopper, Peter J Hulick, Tomasz Huzarski, Evgeny N Imyanitov, Kconfab Investigators, Australian Ovarian Cancer Study Group, Claudine Isaacs, Hidemi Ito, Anna Jakubowska, Ramunas Janavicius, Allan Jensen, Esther M John, Nichola Johnson, Maria Kabisch, Daehee Kang, Miroslav Kapuscinski, Beth Y Karlan, Sofia Khan, Lambertus A Kiemeney, Susanne Kruger Kjaer, Julia A Knight, Irene Konstantopoulou, Veli-Matti Kosma, Vessela Kristensen, Jolanta Kupryjanczyk, Ava Kwong, Miguel De La Hoya, Yael Laitman, Diether Lambrechts, Nhu Le, Kim De Leeneer, Jenny Lester, Douglas A Levine, Jingmei Li, Annika Lindblom, Jirong Long, Artitaya Lophatananon, Jennifer T Loud, Karen Lu, Jan Lubinski, Arto Mannermaa, Siranoush Manoukian, Loic Le Marchand, Sara Margolin, Frederik Marme, Leon F A G Massuger, Keitaro Matsuo, Sylvie Mazoyer, Lesley Mcguffog, Catriona Mclean, Iain Mcneish, Alfons Meindl, Usha Menon, Arjen R Mensenkamp, Roger L Milne, Marco Montagna, Kirsten B Moysich, Kenneth Muir, Anna Marie Mulligan, Katherine L Nathanson, Roberta B Ness, Susan L Neuhausen, Heli Nevanlinna, Silje Nord, Robert L Nussbaum, Kunle Odunsi, Kenneth Offit, Edith Olah, Olufunmilayo I Olopade, Janet E Olson, Curtis Olswold, David O'Malley, Irene Orlow, Nick Orr, Ana Osorio, Sue Kyung Park, Celeste L Pearce, Tanja Pejovic, Paolo Peterlongo, Georg Pfeiler, Catherine M Phelan, Elizabeth M Poole, Katri Pylkäs, Paolo Radice, Johanna Rantala, Muhammad Usman Rashid, Gad Rennert, Valerie Rhenius, Kerstin Rhiem, Harvey A Risch, Gus Rodriguez, Mary Anne Rossing, Anja Rudolph, Helga B Salvesen, Suleeporn Sangrajrang, Elinor J Sawyer, Joellen M Schildkraut, Marjanka K Schmidt, Rita K Schmutzler, Thomas A Sellers, Caroline Seynaeve, Mitul Shah, Chen-Yang Shen, Xiao-Ou Shu, Weiva Sieh, Christian F Singer, Olga M Sinilnikova, Susan Slager, Honglin Song, Penny Soucy, Melissa C Southey, Marie Stenmark-Askmalm, Dominique Stoppa-Lyonnet, Christian Sutter, Anthony Swerdlow, Sandrine Tchatchou, Manuel R Teixeira, Soo H Teo, Kathryn L Terry, Mary Beth Terry, Mads Thomassen, Maria Grazia Tibiletti, Laima Tihomirova, Silvia Tognazzo, Amanda Ewart Toland, Ian Tomlinson, Diana Torres, Thérèse Truong, Chiu-Chen Tseng, Nadine Tung, Shelley S Tworoger, Celine Vachon, Ans M W Van Den Ouweland, Helena C Van Doorn, Elizabeth J Van Rensburg, Laura J Van't Veer, Adriaan Vanderstichele, Ignace Vergote, Joseph Vijai, Qin Wang, Shan Wang-Gohrke, Jeffrey N Weitzel, Nicolas Wentzensen, Alice S Whittemore, Hans Wildiers, Robert Winqvist, Anna H Wu, Drakoulis Yannoukakos, Sook-Yee Yoon, Jyh-Cherng Yu, Wei Zheng, Ying Zheng, Kum Kum Khanna, Jacques Simard, Alvaro N Monteiro, Juliet D French, Fergus J Couch, Matthew L Freedman, Douglas F Easton, Alison M Dunning, Paul D Pharoah, Stacey L Edwards, Georgia Chenevix-Trench, Antonis C Antoniou, Simon A Gayther Sep 2025

Author Correction: Functional Mechanisms Underlying Pleiotropic Risk Alleles At The 19p131 Breast-Ovarian Cancer Susceptibility Locus, Kate Lawrenson, Siddhartha Kar, Karen Mccue, Karoline Kuchenbaeker, Kyriaki Michailidou, Jonathan Tyrer, Jonathan Beesley, Susan J Ramus, Qiyuan Li, Melissa K Delgado, Janet M Lee, Kristiina Aittomäki, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Banu K Arun, Brita Arver, Elisa V Bandera, Monica Barile, Rosa B Barkardottir, Daniel Barrowdale, Matthias W Beckmann, Javier Benitez, Andrew Berchuck, Maria Bisogna, Line Bjorge, Carl Blomqvist, William Blot, Natalia Bogdanova, Anders Bojesen, Stig E Bojesen, Manjeet K Bolla, Bernardo Bonanni, Anne-Lise Børresen-Dale, Hiltrud Brauch, Paul Brennan, Hermann Brenner, Fiona Bruinsma, Joan Brunet, Shaik Ahmad Buhari, Barbara Burwinkel, Ralf Butzow, Saundra S Buys, Qiuyin Cai, Trinidad Caldes, Ian Campbell, Rikki Cannioto, Jenny Chang-Claude, Jocelyne Chiquette, Ji-Yeob Choi, Kathleen B M Claes, Linda S Cook, Angela Cox, Daniel W Cramer, Simon S Cross, Cezary Cybulski, Kamila Czene, Mary B Daly, Francesca Damiola, Agnieszka Dansonka-Mieszkowska, Hatef Darabi, Joe Dennis, Peter Devilee, Orland Diez, Jennifer A Doherty, Susan M Domchek, Cecilia M Dorfling, Thilo Dörk, Martine Dumont, Hans Ehrencrona, Bent Ejlertsen, Steve Ellis, Christoph Engel, Eunjung Lee, D Gareth Evans, Peter A Fasching, Lidia Feliubadalo, Jonine Figueroa, Dieter Flesch-Janys, Olivia Fletcher, Henrik Flyger, Lenka Foretova, Florentia Fostira, William D Foulkes, Brooke L Fridley, Eitan Friedman, Debra Frost, Gaetana Gambino, Patricia A Ganz, Judy Garber, Montserrat García-Closas, Aleksandra Gentry-Maharaj, Maya Ghoussaini, Graham G Giles, Rosalind Glasspool, Andrew K Godwin, Mark S Goldberg, David E Goldgar, Anna González-Neira, Ellen L Goode, Marc T Goodman, Mark H Greene, Jacek Gronwald, Pascal Guénel, Christopher A Haiman, Per Hall, Emily Hallberg, Ute Hamann, Thomas V O Hansen, Patricia A Harrington, Mikael Hartman, Norhashimah Hassan, Sue Healey, Florian Heitz, Josef Herzog, Estrid Høgdall, Claus K Høgdall, Frans B L Hogervorst, Antoinette Hollestelle, John L Hopper, Peter J Hulick, Tomasz Huzarski, Evgeny N Imyanitov, Kconfab Investigators, Australian Ovarian Cancer Study Group, Claudine Isaacs, Hidemi Ito, Anna Jakubowska, Ramunas Janavicius, Allan Jensen, Esther M John, Nichola Johnson, Maria Kabisch, Daehee Kang, Miroslav Kapuscinski, Beth Y Karlan, Sofia Khan, Lambertus A Kiemeney, Susanne Kruger Kjaer, Julia A Knight, Irene Konstantopoulou, Veli-Matti Kosma, Vessela Kristensen, Jolanta Kupryjanczyk, Ava Kwong, Miguel De La Hoya, Yael Laitman, Diether Lambrechts, Nhu Le, Kim De Leeneer, Jenny Lester, Douglas A Levine, Jingmei Li, Annika Lindblom, Jirong Long, Artitaya Lophatananon, Jennifer T Loud, Karen Lu, Jan Lubinski, Arto Mannermaa, Siranoush Manoukian, Loic Le Marchand, Sara Margolin, Frederik Marme, Leon F A G Massuger, Keitaro Matsuo, Sylvie Mazoyer, Lesley Mcguffog, Catriona Mclean, Iain Mcneish, Alfons Meindl, Usha Menon, Arjen R Mensenkamp, Roger L Milne, Marco Montagna, Kirsten B Moysich, Kenneth Muir, Anna Marie Mulligan, Katherine L Nathanson, Roberta B Ness, Susan L Neuhausen, Heli Nevanlinna, Silje Nord, Robert L Nussbaum, Kunle Odunsi, Kenneth Offit, Edith Olah, Olufunmilayo I Olopade, Janet E Olson, Curtis Olswold, David O'Malley, Irene Orlow, Nick Orr, Ana Osorio, Sue Kyung Park, Celeste L Pearce, Tanja Pejovic, Paolo Peterlongo, Georg Pfeiler, Catherine M Phelan, Elizabeth M Poole, Katri Pylkäs, Paolo Radice, Johanna Rantala, Muhammad Usman Rashid, Gad Rennert, Valerie Rhenius, Kerstin Rhiem, Harvey A Risch, Gus Rodriguez, Mary Anne Rossing, Anja Rudolph, Helga B Salvesen, Suleeporn Sangrajrang, Elinor J Sawyer, Joellen M Schildkraut, Marjanka K Schmidt, Rita K Schmutzler, Thomas A Sellers, Caroline Seynaeve, Mitul Shah, Chen-Yang Shen, Xiao-Ou Shu, Weiva Sieh, Christian F Singer, Olga M Sinilnikova, Susan Slager, Honglin Song, Penny Soucy, Melissa C Southey, Marie Stenmark-Askmalm, Dominique Stoppa-Lyonnet, Christian Sutter, Anthony Swerdlow, Sandrine Tchatchou, Manuel R Teixeira, Soo H Teo, Kathryn L Terry, Mary Beth Terry, Mads Thomassen, Maria Grazia Tibiletti, Laima Tihomirova, Silvia Tognazzo, Amanda Ewart Toland, Ian Tomlinson, Diana Torres, Thérèse Truong, Chiu-Chen Tseng, Nadine Tung, Shelley S Tworoger, Celine Vachon, Ans M W Van Den Ouweland, Helena C Van Doorn, Elizabeth J Van Rensburg, Laura J Van't Veer, Adriaan Vanderstichele, Ignace Vergote, Joseph Vijai, Qin Wang, Shan Wang-Gohrke, Jeffrey N Weitzel, Nicolas Wentzensen, Alice S Whittemore, Hans Wildiers, Robert Winqvist, Anna H Wu, Drakoulis Yannoukakos, Sook-Yee Yoon, Jyh-Cherng Yu, Wei Zheng, Ying Zheng, Kum Kum Khanna, Jacques Simard, Alvaro N Monteiro, Juliet D French, Fergus J Couch, Matthew L Freedman, Douglas F Easton, Alison M Dunning, Paul D Pharoah, Stacey L Edwards, Georgia Chenevix-Trench, Antonis C Antoniou, Simon A Gayther

Faculty, Staff and Student Publications

No abstract provided.


Increased Circulating Th17 Cells And Altered Cd4 T Cell Maturation And Differentiation In Active Tuberculosis With Type 2 Diabetes: A Pilot Study, Paul Ogongo, Yoscelina Estrella Martinez-Lopez, Anthony Tran, Cecilia S. Lindestam Arlehamn, Alessandro Sette, Ilse A. Dominguez-Trejo, Genesis P. Aguillón-Durán, Esperanza M. Garcia-Oropeza, Blanca I. Restrepo Sep 2025

Increased Circulating Th17 Cells And Altered Cd4 T Cell Maturation And Differentiation In Active Tuberculosis With Type 2 Diabetes: A Pilot Study, Paul Ogongo, Yoscelina Estrella Martinez-Lopez, Anthony Tran, Cecilia S. Lindestam Arlehamn, Alessandro Sette, Ilse A. Dominguez-Trejo, Genesis P. Aguillón-Durán, Esperanza M. Garcia-Oropeza, Blanca I. Restrepo

School of Medicine Publications

Introduction: Type 2 diabetes (T2D) is a major risk factor for developing tuberculosis (TB). However, understanding the role of defective T cell responses in T2D and TB has been difficult, largely due to inconsistencies across studies. These discrepancies often stem from T cell subset classification primarily relying on cytokine expression profiles, which may not fully capture the complexity of T cell maturation, differentiation, and function in TB patients with T2D.

Objective and methods: In this pilot study, we sought to identify alterations in phenotypic and ex vivo responses of CD4 T cells to Mycobacterium tuberculosis (Mtb) antigens in people with …


2025-09-08 Provost's Pac-22 Response To Questions, Morehead State University. Faculty Senate. Sep 2025

2025-09-08 Provost's Pac-22 Response To Questions, Morehead State University. Faculty Senate.

Faculty Senate Records

Responses given by Provost Chris Schroeder to questions sent by Faculty Senate President Annie Adams regarding the revisal of PAc-22 on September 8, 2025.


Chimes: September 8, 2025, Calvin University Sep 2025

Chimes: September 8, 2025, Calvin University

Chimes

Kicking off 150 years of Calvin by Ashley Hamons & Maya Oeverman

Calvin hosts Grand Rapids area churches for annual and ministry fair by McKenna Wilkinson

Investing in Wellness: Group fitness fee aims to support expansion by Hendrik Beelen & Zach Kern

New rhythms: Calvin chapel transitions to MWF format by Ella Vanden Berg

"No-AI" policies and human flourishing by Joe Toly

A letter to the KE steps by Ian Tjoelker


Integrative Analysis Of Lung Adenocarcinoma Across Diverse Ethnicities And Exposures, Shankha Satpathy, Natalie M Clark, Yi-Ju Chen, Noshad Hosseini, Ya-Hsuan Chang, Yi Hsiao, Jonathan T Lei, Francesca Petralia, Jin-Shing Chen, Yifat Geffen, David I Heiman, Indranil Paul, Hanbyul Cho, Michelle Hollenberg, Giacomo B Marino, Kuen-Tyng Lin, Rahul Mannan, C Jackson White, Joe Allen, Shayan C Avanessian, M Harry Kane, Ashley Wolfe, Miloni Kinarivala, Wenke Liu, Shankara Anand, Mong-Wei Lin, Moe Haines, Erik J Bergstrom, Grant Hussey, Ginny Xiaohe Li, Deepak C Mani, Hao Fang, Eric J Jaehnig, Hasmik Keshishian, Brecca Miller, Kang-Yi Su, Yi-Jing Hsiao, Hsao-Hsun Hsu, Min-Shu Hsieh, Kuo-Hsuan Hsu, Alexi Monovoukas, Simone Gohsman, John R Thorup, Yamei Deng, Yo Akiyama, Eden Deng, Eric Sheng-Wen Chen, Azra Krek, Rodrigo Espinoza, Weiping Ma, Daniel Charytonowicz, Robert Sebra, Jyun-Hong Lin, Yan-Si Chen, Yin-Chen Hsu, Ze-Shiang Lin, Kun-Chieh Chen, Chang-Wei Yeh, Yu-Tai Wang, Alexander J Lazar, Mehdi Mesri, Eunkyung An, Xu Zhang, Karl R Clauser, David Fenyö, Arul M Chinnaiyan, Bing Zhang, Li Ding, Kelly Ruggles, Chelsea Newton, Hui Zhang, Pei Wang, Galen Hostetter, Gilbert S Omenn, Chandan Kumar-Sinha, Mathangi Thiagarajan, Ramaswamy Govindan, Paul Paik, Abhijit Parolia, Qing K Li, Avi Ma'ayan, Gad A Getz, Saravana M Dhanasekaran, Ana I Robles, Gee-Chen Chang, Pan-Chyr Yang, Sung-Liang Yu, Hsuan-Yu Chen, Alexey I Nesvizhskii, Steven A Carr, D R Mani, Marcin P Cieslik, Yu-Ju Chen, Michael A Gillette, Taiwan Cancer Moonshot Program, Clinical Proteomic Tumor Analysis Consortium Sep 2025

Integrative Analysis Of Lung Adenocarcinoma Across Diverse Ethnicities And Exposures, Shankha Satpathy, Natalie M Clark, Yi-Ju Chen, Noshad Hosseini, Ya-Hsuan Chang, Yi Hsiao, Jonathan T Lei, Francesca Petralia, Jin-Shing Chen, Yifat Geffen, David I Heiman, Indranil Paul, Hanbyul Cho, Michelle Hollenberg, Giacomo B Marino, Kuen-Tyng Lin, Rahul Mannan, C Jackson White, Joe Allen, Shayan C Avanessian, M Harry Kane, Ashley Wolfe, Miloni Kinarivala, Wenke Liu, Shankara Anand, Mong-Wei Lin, Moe Haines, Erik J Bergstrom, Grant Hussey, Ginny Xiaohe Li, Deepak C Mani, Hao Fang, Eric J Jaehnig, Hasmik Keshishian, Brecca Miller, Kang-Yi Su, Yi-Jing Hsiao, Hsao-Hsun Hsu, Min-Shu Hsieh, Kuo-Hsuan Hsu, Alexi Monovoukas, Simone Gohsman, John R Thorup, Yamei Deng, Yo Akiyama, Eden Deng, Eric Sheng-Wen Chen, Azra Krek, Rodrigo Espinoza, Weiping Ma, Daniel Charytonowicz, Robert Sebra, Jyun-Hong Lin, Yan-Si Chen, Yin-Chen Hsu, Ze-Shiang Lin, Kun-Chieh Chen, Chang-Wei Yeh, Yu-Tai Wang, Alexander J Lazar, Mehdi Mesri, Eunkyung An, Xu Zhang, Karl R Clauser, David Fenyö, Arul M Chinnaiyan, Bing Zhang, Li Ding, Kelly Ruggles, Chelsea Newton, Hui Zhang, Pei Wang, Galen Hostetter, Gilbert S Omenn, Chandan Kumar-Sinha, Mathangi Thiagarajan, Ramaswamy Govindan, Paul Paik, Abhijit Parolia, Qing K Li, Avi Ma'ayan, Gad A Getz, Saravana M Dhanasekaran, Ana I Robles, Gee-Chen Chang, Pan-Chyr Yang, Sung-Liang Yu, Hsuan-Yu Chen, Alexey I Nesvizhskii, Steven A Carr, D R Mani, Marcin P Cieslik, Yu-Ju Chen, Michael A Gillette, Taiwan Cancer Moonshot Program, Clinical Proteomic Tumor Analysis Consortium

Faculty, Staff and Students Publications

Lung adenocarcinomas (LUAD) are a pressing global health problem with enduring lethality and rapidly shifting epidemiology. Proteogenomic studies integrating proteomics and post-translational modifications with genomics can identify clinical strata and oncogenic mechanisms, but have been underpowered to examine effects of ethnicity, smoking and environmental exposures, or sex on this heterogeneous disease. This comprehensive proteogenomic analysis of LUAD tumors and matched normal adjacent tissues from 406 patients across diverse geographic and demographic backgrounds explores the impact of understudied driver mutations, prognostic role of chromosomal instability, patterns of immune signaling, differential and sex-specific effects of endogenous mutagens and environmental carcinogens, and pathobiology …