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Pertussis In Infancy: A Case Of Delayed Diagnosis, Ana Hernandez-Puga

All Publications

Bordetella pertussis is a gram-negative bacterium that primarily infects the respiratory tract. We report the case of a 13-month-old male patient who developed pertussis. At the initial clinic presentation, the diagnosis was not immediately considered, as the early manifestations closely mimicked those of a viral upper respiratory infection. As the illness progressed, the classic paroxysmal cough with inspiratory "whoop" became apparent, prompting the correct diagnosis. At that time, a nasopharyngeal swab was obtained, which tested positive for Bordetella pertussis by polymerase chain reaction (PCR). The patient was prescribed a five-day course of azithromycin, and close contacts were given prophylactic treatment. …

Aphasia In South Asian Languages (Asal) Project: A Protocol Of Connected Speech Tasks For Investigating Cross-Linguistic Grammatical Profiles In Aphasia For South Asian Languages, Arpita Bose, Sakshi Bhatia, Lakshmi Venkatesh, Sayantani Banerjee, Gurujegan Murugesan, Sunila John, Sakshi Upadhyay, Manaswita Dutta, Mythili Menon, Danielle Fahey, Multiple Additional Authors

Speech and Hearing Sciences Faculty Publications and Presentations

Background

Languages vary in their syntactic (e.g. word order in sentences), lexical (e.g. presence of specific word classes), and morphological (e.g. inflectional or derivational forms of words) properties. This cross-linguistic variation in language typology influences the manifestation of agrammatic symptoms. However, most theoretical models of agrammatism are based on English and a few European languages, limiting their generalizability. This narrow focus neglects the rich syntactic, lexical and morphological variations available in languages globally. Clinically, the lack of language-specific characteristics of agrammatic impairments limits translational potential for precise and improved diagnosis. The Aphasia in South Asian Languages (ASAL) project addresses this …

Trajectories Of Recovery After Intravenous Propofol Versus Inhaled Volatile Anaesthesia (Thrive) Randomised Controlled Trial In The Usa: A Protocol, Bethany R Tellor Pennington, Laura Swisher, Mara L Bollini, Michael S Avidan, Et Al.

2020-Current year OA Pubs

INTRODUCTION: Millions of patients receive general anaesthesia every year with either propofol total intravenous anaesthesia (TIVA) or inhaled volatile anaesthesia (INVA). It is currently unknown which of these techniques is superior in relation to patient experience, safety and clinical outcomes. The primary aims of this trial are to determine (1) whether patients undergoing (a) major inpatient surgery, (b) minor inpatient surgery or (c) outpatient surgery have a superior quality of recovery after INVA or TIVA and (2) whether TIVA confers no more than a small (0.2%) increased risk of definite intraoperative awareness than INVA.

METHODS AND ANALYSIS: This protocol was …

The New England Trail, End To End In Five Days: A Running Couple Test Their Limits, Scott Livingston

Appalachia

A moment-by-moment narrative of a grueling run from Mount Monadnock in New Hampshire to Guilford, Connecticut from June 17 through June 22, 2020.

Development Of A Water Temperature Modeling Platform To Support Short- And Long-Term Water Temperature Management In Reservoir-River Systems, Michael Deas, Yung-Hsin Sun, John Degeorge, Benjamin T. Saenz, Thomas A. Evans, Scott Burdick-Yahya, Stephen Andrews, Jeff Schuyler, William Candy, Lin Zheng, Scott Wells, Multiple Additional Authors

Civil and Environmental Engineering Faculty Publications and Presentations

The U.S. Department of the Interior, Bureau of Reclamation (Reclamation) supports water temperature management for fishery species protection in downstream river reaches below Central Valley Project (CVP) reservoirs in the Sacramento, American, and Stanislaus River systems. The Water Temperature Modeling Platform (WTMP) Project was initiated to modernize and enhance modeling capabilities to predict summer–fall water temperature through reservoir cold water pool management using temperature control facilities designed for temperature management. The WTMP supports forecasts, historical analyses, and long-term planning efforts and advances previous modeling approaches by using an integrated modeling platform. This platform includes a data management system that acquires …

Naming Practice Effects And Inconsistencies Relate To Treatment Outcome In People With Aphasia, Janina Wilmskoetter, Katherine Blackwood, Sigfus Kristinsson, Grant Walker, Julius Fridriksson, Deena Schwen Blackett, Dirk B. Den Ouden, Chris Rorden, Argye E. Hillis, Gregory Hickok, Sara Sayers, Leigh Ann Spell, Leonardo Bonilha

Communication Sciences and Disorders Faculty Articles and Research

Background and aims

Method

Somatostatin Receptor 2 Overexpression In Hepatocellular Carcinoma: Implications For Cancer Biology And Therapeutic Applications, Servando Hernandez Vargas, Solmaz Aghaamiri, Jack T Adams, Tyler M Bateman, Belkacem Acidi, Sukhen C Ghosh, Vahid Khalaj, Ahmed O Kaseb, Hop S Tran Cao, Majid Momeny, Ali Azhdarinia

The Brown Foundation: Institute of Molecular Medicine

Background: Somatostatin receptor 2 (SSTR2), a G protein-coupled receptor, is overexpressed in multiple malignancies, including hepatocellular carcinoma (HCC). While SSTR2 has traditionally been viewed as an inhibitory receptor involved in suppressing hormone secretion and cell proliferation, emerging evidence suggests a more complex role in cancer biology. However, the functional implications of SSTR2 expression in HCC remain poorly understood. This study aimed to systematically investigate the molecular landscape associated with SSTR2 expression in HCC and evaluate its potential as a therapeutic target.

Methods: SSTR2 expression patterns across 22 tumor types were assessed using TNMplot, and its expression in HCC was further …

Register Blocking: A Source-To-Source Analytical Modelling Approach For Affine Loop Kernels, Theologos Anthimopoulos, Georgios Keramidas, Vasilios Kelefouras, Iakovos Stamoulis

School of Engineering, Computing and Mathematics

Register Blocking (RB), also known as ‘Register-level Tiling’ or ‘unroll-and-jam,’ is a key compiler optimizationfor developing efficient micro-kernels. However, applying RB effectively is a complex task due to severalchallenges. First, the exploration space of possible RB configurations is vast. Second, RB and loop permutationare interdependent; therefore, addressing both optimizations simultaneously further inflates the explorationspace. Third, the effectiveness of RB is highly dependent on the target hardware platform and the specific loopkernel being optimized. As a result, an extensive and time-consuming fine-tuning process is necessary forachieving an efficient implementation.To address these challenges, a source-to-source analytical modelling approach is proposed. The RB …

Angela Moody-Howard

African American Funeral Programs

Funeral program for Angela Moody-Howard. Service held on September 13, 2025 in Statesboro, Georgia

An Evaluation Study Of Entry-To-Practice Competency Requirements For Rns In The Kingdom Of Eswatini, Bethany A. Murray, Nkosinathi Rejoice Nkwanyana

International Nursing Research Congress (INRC)

The purpose of this study was to evaluate the entry-to-practice (ETP) licensure requirements for RNs in The Kingdom of Eswatini. Eswatini implemented RN licensing requirements in 2020. Previously, RNs were licensed by graduation from a nursing training institution. Now, nurses must also pass a written general nursing exam and submit a signed record book of clinical practice skills (SCCRB) (1). RNs who want to practice midwifery or mental health have additional requirements. In 2023, the Eswatini Nursing Council (ENC) collaborated with a midwestern U.S. nursing school to evaluate the ETP requirements. The Nursing Registrar of Eswatini and nursing faculty from …

Perceived Stress And Compassion Satisfaction Among Nurses: The Mediating Role Of Disaster Readiness, Hsueh-Hsing Pan, Peng-Ching Hsiao

International Nursing Research Congress (INRC)

Background: Nurses’ disaster readiness is influenced by stress, self-efficacy, and family support. Understanding the mediating roles of these factors is crucial for enhancing preparedness and ensuring effective patient care during disasters. With the increasing occurrence of disasters, understanding how stress impacts disaster readiness and the potential mediating roles of self-efficacy and family support is essential.

Aim: To examine whether self-efficacy and family support mediate the relationship between stress and disaster readiness among nurses.

Methods: A cross-sectional study was conducted with 476 registered nurses. Data were collected on demographics, work-related characteristics, the Perceived Stress Scale-14, the General Self-Efficacy Scale, perceived …

Enhancing Patient Safety: Nurses’ Perspectives On Barcode Point-Of-Care Systems, Jimi Han, Hee Sun Kang

International Nursing Research Congress (INRC)

Background: Barcode technology in healthcare has advanced significantly and has become essential for patient safety. Multifunctional devices, such as personal digital assistants (PDAs), are integrated with electronic health records, enabling real-time documentation through barcode scanning at the patient’s bedside.

Aim: This study aimed to explore nurses’ perspectives regarding the barcode point-of-care (POC) system using mobile PDAs, focusing on medication administration, blood transfusions, and specimen collection.

Methods: This qualitative descriptive study collected data through focus group interviews with 24 nurses between September and November 2023. The data were analyzed using content analysis.

Results: Participants acknowledged that although …

Moving Towards Social Justice: Applying Partnership Frameworks Drawn From The Natural Sciences, Dante Nguyen

Teaching and Learning Together in Higher Education

No abstract provided.

Cultivating Critical Hope: Reflections On Pedagogical Partnerships In Higher Education, Austen Morris

Teaching and Learning Together in Higher Education

No abstract provided.

The Tragic Automatic: An Analysis Of The Default Positioning Within Pedagogy, Chyane Sims

Teaching and Learning Together in Higher Education

No abstract provided.

Loose Notes From Box 20, Anwar Shaikh Phd

Archives of Anwar Shaikh

This collection includes:

• Handwritten notes titled Proceeds & Profit a la Sraffa discussing balance sheets, profit, and simple reproduction (1983, October 7)

• Pages 148–149 from an unidentified publication on investment including a table on estimated returns on investment for 38 US corporations

• An annotated first draft of a paper by Jack Glen, Ajit Singh, and Rudolph Matthias titled How Competitive are the Emerging Markets? An Analysis of Corporate Rates of Return from Nine Emerging Markets, prepared for an IMF Research Department Seminar (1998, July 21)

• An annotated paper by Michel-Stéphane Dupertuis and Ajit Sinha titled A Sraffian Critique of …

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Graphs And Notes On Interest Rate And Profits, Anwar Shaikh Phd

Archives of Anwar Shaikh

This collection includes:

• A graph titled Real Interest Rates, US and Trading Partners (1961–2005) from a file named International Real Interest Rate Arbitrage.xlsx

• A graph showing deviations in real interest rates for the US and trading partners (1961–2005) from a file named International Real Interest Rate Arbitrage.xlsx

• A graph of the average IROP for various industries without exclusions (1988–2005) from a file named IROPNov12073.xls

• Handwritten notes with equations for incorrect and correct IROP calculations

• A collection of charts from a file named IROP_Dec28excl1 including line graphs of the average of r, IROP, and rinvest; bar charts of period average rates …

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Unveiling The Unexpected: Duodenal Ulcer As A Manifestation Of Breast Cancer Metastasis, Emmanuel Gbadehan, Mohammad Abubaker, Parth Adrejiya, Khwaja Haq, Teresa Varghese, Joy Chaudhari, Gurkeerat Singh, Ashok Kanugula

Journal of Community Hospital Internal Medicine Perspectives

Breast cancer typically metastasizes to the lymph nodes, lungs, bones, and liver. However, gastrointestinal (GI) involvement is exceedingly rare, particularly presenting as duodenal ulcers. Such metastases often mimic primary GI malignancies, leading to nonspecific symptoms like abdominal pain, anorexia, bleeding, and vomiting, which can delay accurate diagnosis. Early recognition through appropriate diagnostic evaluations is crucial to prevent disease progression. We report a unique case of an 86-year-old woman with multiple comorbidities who presented with multiple gastrointestinal ulcers. Further investigation revealed these lesions to be manifestations of metastatic breast cancer. This case underscores the importance of considering metastatic breast cancer in …

Severe Hyponatremia Presenting With Mild Symptoms And Multifactorial Etiology, Nathaniel Lin, Muhammad Cheema, Usman Fahim, Abdullah Ali, Andrew Weber

Journal of Community Hospital Internal Medicine Perspectives

Hyponatremia is a common electrolyte disturbance; however, serum sodium level of 99 mEq/L without severe symptoms or known duration is rare and noteworthy. We report a case of an 87-year-old female who presented with fatigue, decreased appetite, and mild emesis for the past 2 days in which blood work revealed a serum sodium level 99 mEq/L. The etiology of hyponatremia in an elderly patient may be complex due to higher likelihood of co-morbid medical conditions. Additionally, syndrome of inappropriate antidiuretic hormone (SIADH) can pose a diagnostic challenge as fewer than 50% of patients have typical lab results that confirm the …

Methotrexate Toxicity Management In Polymyalgia Rheumatica: A Case Report, Devi Meghana Kotharu, Sai Diksha Vutukuru, Prafullkumar Patel, Athmananda Nanjundappa, Sumanth Kumar Bandaru

Journal of Community Hospital Internal Medicine Perspectives

Methotrexate (MTX) is an anti-folate drug with anti-inflammatory and anti-proliferative properties. Low-dose methotrexate (10-25mg/week) is widely recognized as a safe and effective treatment for various autoimmune disorders. While toxicity from low dose methotrexate is uncommon it can lead to severe complications like pancytopenia. We present a case of a 68-year-old male with a history of steroid-resistant Polymyalgia Rheumatica on methotrexate (20 mg weekly) and prednisone. He presented to the emergency room with oral mucosal lesions and reduced oral intake. Upon evaluation, he was found to have pancytopenia and transaminitis, raising concern for methotrexate toxicity. Treatment included folinic acid rescue therapy …

Concurrent Histoplasmosis & Blastomycosis In A Young Woman, Gizem Reyhanoglu, Mohsan Khan, Andrea Venturini

Journal of Community Hospital Internal Medicine Perspectives

Background:

Histoplasmosis capsulatum and Blastomyces dermatitidis are fungi that are uniquely distributed across the United States. Co-infection with both fungi remains uncommon. The literature review of coinfection was limited to three cases. Only two cases were recorded in humans. Infection can yield symptoms ranging from asymptomatic to life-threatening. On radiographic imaging, diffuse reticulonodular infiltrates with hilar or mediastinal lymphadenopathy can be seen. Management depends on the severity of the disease and the patient’s immune state.

Case Description:

A 35-year-old female with a medical history significant for HIV and substance use disorder presented to the hospital with severe lower abdominal pain, …

Hamiltonian-Based Quantum Generative Autoencoder System And Method Thereof, Fuming Guo

Defensive Publications Series

The present disclosure relates to a system and method for Hamiltonian-Based Quantum Generative Autoencoder. The autoencoder leverages a novel Hamiltonian based quantum Al generative model to resolve anomaly detection in financial transaction data. An hybrid architecture, i.e., potential of quantum computing and generative AI based approach is leveraged in this disclosure to capture complex patterns and correlations in high-dimensional financial data. This system employes a series of parameterized Hamiltonians at least for processes like encoding, latent space representation, and decoding, which are implemented as quantum circuits using Trotterization techniques. Particularly, the system incorporates physical-inspired principles into the area of financial …

Section Iii -- College Of Liberal Arts Policies And Procedures (Updated 9/12/2025), All Faculty

Faculty Handbooks

No abstract provided.

"Elements Don’T Mix!": Unearthing Racial Scripts And A Rhetorical Economy Of Whiteness In Disney And Pixar's Elemental, Linsay M. Cramer, Gabriel A. Cruz

Communication, Media, and Culture

Using a narrative rhetorical approach, we map how Disney and Pixar’s 2023 film, Elemental, sustains a rhetorical economy of whiteness, as theorized by Asen and Kelly, which emphasizes the degree to which rhetorical constructions of racial difference are foundational to whiteness and economic systems. We identify and critique how Elemental discursively contributes to a system of exclusivity for those within the bounds of whiteness concerning economic mobility via racial scripts. Created and produced during Joe Biden’s United States (U.S.) presidential term (2021–2025), Elemental offers a metaphorical tale that engages the fractious, politically conservative anxieties concerning diversity, equity, and inclusion (DEI) …

Ucc Minutes Sept 12, 2025, Undergraduate Curriculum Committee

Undergraduate Currirculum Committee Minutes

No abstract provided.

Christian Lauria V. Lieb

2025 Decisions

USDC for the Western District of Pennsylvania

Lee Evans V. City Of Newark

2025 Decisions

USDC for the District of New Jersey

Nina Jankowicz V. Fox News Network Llc

2025 Decisions

USDC for the District of Delaware

Usa V. James Larnerd

2025 Decisions

USDC for the Middle District of Pennsylvania

Non-Neutralizing Antibodies To Influenza A Matrix-Protein-2-Ectodomain Are Broadly Effective Therapeutics And Resistant To Viral Escape Mutations., Teha Kim, Lynn Bimler, Sydney L Ronzulli, Amber Y Song, Scott K Johnson, Cheryl A Jones, S Mark Tompkins, Silke Paust

Faculty Research 2025

Influenza A viruses remain a global health threat, yet no universal antibody therapy exists. Clinical programs have centered on neutralizing mAbs, only to be thwarted by strain specificity and rapid viral escape. We instead engineered three non-neutralizing IgG2a mAbs that target distinct, overlapping epitopes within the conserved N terminus of the M2 ectodomain (M2e). Combined at low dose, this "triple M2e-mAb" confers robust prophylactic and therapeutic protection in mice challenged with diverse human and zoonotic IAV strains, including highly pathogenic variants. Therapeutic efficacy depends on Fc-mediated effector activity via FcγRI, FcγRIII, and FcγRIV, rather than in vitro neutralization. Serial passaging …