Digital Commons Network^™

Further Insights Into The Network Link Outlier Factor's (Nlof) Light-Load Penalty, Sunday Oluwaleke Ogundele

Open Access Theses & Dissertations

This research investigates the performance of the Network Link Outlier Factor with Most Likely Links (NLOF:MLL), under varying network load conditions. Earlier studies reported that the NLOF:MLL algorithm experienced a noticeable drop in fault-localization accuracy when operating in lightly loaded networks. To further examine this limitation, 240 experiments were carried out to observe how the algorithm responds as overall network load increases. The evaluation focused on the classification performance metrics: precision, recall, and F1-score. The results show that NLOF:MLL’s effectiveness improves as network load increases but that the rate of improvement slows progressively, eventually stabilizing in a pattern consistent with …

Decoupling Piezoelectric And Pyroelectric Effects In Anisotropic Polymer-Ceramic Lattices Produced Via Fused Filament Fabrication, Sofia Alexandra Perez

Open Access Theses & Dissertations

This thesis investigates how multi-material fused filament fabrication (FFF) can be used to engineer lattice structures that decouple piezoelectric and pyroelectric responses within a single polymer–ceramic composite. A hybrid ABS–BaTiO3/PLA lattice—referred to as the Hybrid PIZCAL—was designed to direct mechanical strain along the Z-axis while suppressing deformation in the transverse directions. After thermal poling, the lattice exhibited a 293% increase in Z-axis voltage sensitivity compared to a monolithic ABS–BaTiO3 cube and significantly reduced off-axis electromechanical output. Finite element simulations and directional compression testing confirmed that geometric anisotropy and material zoning produce strong, axis-selective piezoelectric behavior. The second part of this …

Applying The Quadruple Process Model To A Measure Of Implicit Bias Towards Individuals With Alcohol Use Disorder, Erin Marie Portillo

Open Access Theses & Dissertations

Alcohol use disorders is one of the major burdens of disease, yet it remains one of the disorders with the lowest treatment prevalence. For individuals who seek treatment for their alcohol use disorder, they may experience higher levels of social disintegration, guilt, shame, and stigmatization. Stigma is a multistep process that makes way for stereotypes, prejudice, and acts of discrimination to take place. With labels such as “alcoholic” implying negative connotation and being frequently used, the fear of being stigmatized and negatively labeled often results in delayed or entirely avoided care. Research has turned to the use of implicit measures …

Expression And Purification Of Prohibitin Proteins And Investigation Of Their Interaction With Mycobacterium Tuberculosis’S Virulence Factors, Zeina Rhaim

Open Access Theses & Dissertations

Prohibitin (PHB) is a highly conserved mitochondrial protein involved in cell cycle regulation, apoptosis, mitochondrial integrity, macrophage activation, cytokine production and many other critical cell functions. The prohibitin complex, formed by Prohibitin-1 (PHB1) and Prohibitin-2 (PHB2), functions as a mitochondrial membrane-associated receptor. Cancer, neurodegenerative disorders, and renal conditions were found to be linked to an irregular PHB expression. Emerging evidence has also highlighted a significant role for PHB in tuberculosis (TB), particularly through its interactions with Mycobacterium tuberculosis (Mtb) virulence determinants. The molecular mechanisms by which PHB influences TB pathogenesis remain poorly understood. Our preliminary studies showed that PHB1 was …

Lorentz Invariance And Quantum Coordination: A Neo-Aristotelian Framework For Entanglement And Relativity, Angel Rafael Sosa Muniz

Open Access Theses & Dissertations

The phenomenon of quantum entanglement has been at the center of heated debates among physicists and philosophers since the dawn of the quantum era. The early discussions initiated by Einstein, Podolsky, and Rosen—regarding potential violations of the Principle of Relativity by entangled particles, expressed in the so-called “EPR Paradox”—ultimately culminated in the demonstration of Bell’s theorem and its violations. Since then, philosophers of science and physicists have developed multiple proposals attempting to account for the ontological status of quantum formalism and its possible tension with relativistic principles. This thesis contributes to these efforts by advancing a Neo-Aristotelian ontological framework inspired …

Powder Degradation Analysis In Reused Pure Tungsten For Electron Beam Melting (Ebm), Hernan Valenzuela

Open Access Theses & Dissertations

Additive manufacturing (AM) enables unparalleled design freedom and geometric complexity, driving its adoption in aerospace and medical fields. A major advantage of metal powder AM technologies, such as Electron Beam Melting (EBM), is its ability to reuse unused metal powder, reducing material waste and costs. However, reusing powder repeatedly alters its properties, affecting the final product. Despite its significance, research on powder degradation remains limited, primarily focusing on alloys like Ti-6Al-4V. This thesis investigates the degradation of pure tungsten powder reused over multiple Electron Beam Melting (EBM) cycles. A literature review revealed general powder-reuse mechanisms across additive manufacturing (AM) technologies …

Hubert-Based Models And Evaluation Strategies For Pragmatically-Faithful Speech To Speech Translation, Javier Vazquez

Open Access Theses & Dissertations

Pragmatic fidelity in speech-to-speech translation (S2ST) has largely been understudied, leading to communication tools inadequate to support non-superficial dialog. We aim to improve pragmatic faithfulness in English-Spanish translation through the development of machine learning models that are able to predict a corresponding pragmatic representation in the other language. To evaluate performance, we developed a pipeline that utilizes a recently-developed pragmatic similarity evaluation metric to compare models. Further, we developed models that exploit HuBERT features as these have been found suitable for various prosody and pragmatics related tasks. Our models outperformed human and state-of-the-art predictions, albeit the methodology being limited to …

Ode To The Infomercial, Edward Wade

Open Access Theses & Dissertations

'Ode to the Infomercial' is a poetry collection in five sections which explores themes of contemporary American life, parenthood, and the media landscape. While primarily written in a narrative voice, the poetic approach is as diverse as the content. Interwoven throughout the collection is religious imagery and political posturing accompanied by healthy doses of self-criticism and humor.

Worth The Risk? Standardized Screening To Identify Substance Use Among Patients Before Surgery, Samantha Cooley, Mark C. Bicket, Hanan Mohammed, Yenling Lai, Sarah Evilsizer, Chad M. Brummett, Jennifer F. Waljee

Student Publications

Objective:

We sought to compare the identification of unhealthy substance use before surgery using Tobacco, Alcohol, Prescription medication, and other Substance use (TAPS), a standardized 4-item instrument, versus routine clinical documentation in the electronic medical record (EHR).

Background:

Over 20% of individuals exhibit unhealthy substance use before elective surgery. Routine EHR documentation is often based on nonstandard questions that may not fully capture the extent of substance use and are subject to bias. In contrast, brief standardized screening could provide a more efficient and systematic approach.

Methods:

We conducted a cross-sectional study among adults (≥18 y) at a preoperative clinic …

2025 Author/Title Index To The Journal Of The Michigan Dental Association, Jackie Hammond

The Journal of the Michigan Dental Association

This comprehensive resource indexes articles published throughout 2025 in the Journal of the Michigan Dental Association. The content covers a wide range of topics relevant to Michigan dentistry, practice management, and legal compliance. Articles include findings on dental utilization rates pre- and post-COVID, legal guidance on issues like covenants not to compete and dental records, and clinical topics such as treating children with special needs. The index also features reports on MDA membership, the Foundation’s work, and analyses of generational differences in the workforce.

A Pilot Study Investigating The Impact Of Cigarette Smoking On Oral Nitrate-Reducing Bacteria Within The Oral Microbiome, Tomas L Nicholas, Raul Bescos, Amazon Doble, Katie Muddiman, Paul Kellett, Abish S Stephen, Lisa Du Toit, Robert Witton, Zoë Ls Brookes

Peninsula Dental School

ObjectiveTo evaluate the impact of cigarette smoke on the activity and abundance of oral nitrate reducing bacteria (ONRB) in vivo and in vitro.Materials and MethodsAn observational study comprising of eleven cigarette smokers and thirty-one non-smokers. A saliva and nitrate-rinse sample were collected from each participant to analyse salivary biomarkers and the activity and abundance of ONRB in vivo. Additionally, the effect of cigarette smoke on the nitrate-reducing activity of four Rothia species was investigated in vitro.ResultsThe beta diversity of the oral microbiome was significantly different between smokers and non-smokers (P = 0.0063). Neisseria flavescens and Actinomyces oris were significantly higher …

Strategic Interactions And Gender Cues: Evidence From Social Preference Games, Hernán Bejarano, Matias Busso, Juan Francisco Santos

ESI Working Papers

This paper studies trust, reciprocity, and bargaining using a large-scale online experiment conducted in six Latin American countries. Participants played trust and ultimatum games under randomly assigned conditions in which the gender of their counterpart was either disclosed or withheld. On average, disclosing counterpart gender does not yield statistically detectable effects in either game. However, statistically significant differences emerge by participants' own gender: on average men exhibit higher levels of trust, reciprocity, and generosity in bargaining than women. When disaggregating by participant-counterpart gender pairings, point estimates differ in sign across groups but are generally imprecisely estimated, and differences between interacting …

Now You See It: Evaluating A Small Object Detection Model For Uncrewed Surface Vehicle Operations, Jenna Ehnot

Master's Theses and Capstones

As Uncrewed Surface Vehicle (USV) operations scale in size, distance, and complexity, they increasingly rely on artificial intelligence (AI) algorithms to maintain situational awareness, and operators must understand how algorithm performance may change as camera configuration is adjusted to meet operational needs. This thesis proposes distance-based evaluation strategies that characterize object detection performance in terms directly applicable to USV operations. In this research, a YOLOv5s model was trained to detect small maritime obstacles, focusing on aids to navigation, and the lobster pot floats common in the Gulf of Maine. Three test videos were collected, each capturing a buoy approaching the …

Quantifying Contributions Of Sonar Systems On Marine Soundscapes: A Statistical And Machine Learning Analysis, Reilly Jacob Lessard

Master's Theses and Capstones

A variety of elements are used to characterize marine soundscapes, including natural and anthropogenic sound. One anthropogenic activity that potentially contributes to marine soundscapes, but is not sufficiently understood, is the use of different types of ocean-mapping sonar systems. Sonar systems are used abundantly in marine environments for purposes such as ocean floor mapping and military security purposes [Ryu et al., 2023] [Marszal and Salamon, 2013]. The systems used to conduct this research are the Kongsberg TOPAS PS40 sub-bottom profiler and the RESON SeaBat T51-R multibeam echosounder, along with SoundTrap recorders, which were deployed in the Gulf of Maine. Periods …

“War Is God” And “Unguessed Kinships”: Blood Meridian And Cormac Mccarthy’S “Border Tetralogy”, Seth Reeves

Electronic Theses and Dissertations

This thesis applies the metaphysics of philosopher Gilles Deleuze to Cormac McCarthy’s novel Blood Meridian, arguing that the novel initiates a thread of immanent subjectivity that unfolds throughout the Border Trilogy that follows it. Against a hierarchical metaphysics of transcendence, specifically an inverted Platonic Idealism, Blood Meridian dramatizes an immanent world of “optical democracy,” a prose style that levels the human and nonhuman and eludes subject and object categories. The kid’s autonomy from Judge Holden’s violent domination marks the truncated beginning of a Deleuzian subjectivity of becoming-other and immanent kinship. This incomplete gesture continues in the Border Trilogy, where …

Impact Of Structured Internal Medicine Pharmacotherapy Education In Improving Pharmacist Readiness In Transitioning To An Academic Medical Center, Jude Pierre, Erika Dittmar, Heidi Clarke, Radhan B. Gopalani, Stephanie Palma

Nursing & Health Sciences Research Journal

Introduction: Baptist Hospital of Miami (BHM) is transitioning to an academic medical center by starting medical residency training in July 2025. As healthcare systems expand, pharmacists must ensure safe medication dispensing and provide real-time clinical decision support. To support this transition, a structured internal medicine pharmacotherapy curriculum was developed to refresh clinical knowledge and enhance confidence among experienced clinical pharmacists.

Methods: A single-site, Institutional Review Board-exempt, quality improvement project was conducted at BHM. Inclusion criteria included Clinical Pharmacists 2s (primarily decentralized pharmacists with ≥ 1 year of pharmacy experience at BHM) who completed a structured pharmacotherapy curriculum from January 2025 …

58(3) Front Matter

UBC Law Review

No abstract provided.

Rights, Contract, And Consideration In The Civil Law And Common Law Traditions, Stéphane Sérafin

UBC Law Review

No abstract provided.

Optimizing Pv Solar Array Design By Analysis Of The Industrial And Training Assessment Center (Itac) Database, Angel Samuel Fernandez

Theses and Dissertations

Since 2017, the Industrial Training and Assessment Center (ITAC) at UTRGV has included photovoltaic (PV) system evaluations in its industrial energy assessments. A review of these reports showed inconsistencies in PV system design, including variations in sizing methods, performance assumptions, and application of NEC requirements. To address these issues, this thesis develops a standardized and NEC-compliant methodology for designing PV systems, incorporating demand-based sizing, solar-geometry principles, and electrical calculations guided by NEC Articles 690 and 705.

This thesis focuses on demand-based PV system sizing and incorporates NEC-guided electrical design to ensure technical compliance and safety. System performance is evaluated using …

The Unilateral Neuromuscular Effects Of Cross Education Eccentric-Focused Isokinetic Strength Training With Blood Flow Restriction In Sedentary And Recreationally Active Males, Bryan Mixumi

Theses and Dissertations

PURPOSE: The purpose of this study was to determine if BFR unilateral training protocols can elicit the same or greater cross-education effect as observed with HIGH protocols.

RESULTS: Significant time main effects and trained vs. untrained interactions revealed both training groups improved in isometric and isokinetic strength, work and power across limbs (P < 0.05). EMG analyses showed significant increases in vastus lateralis activation, with limb-specific neural adaptations but no group differences (P < 0.05) suggesting potential cross-education influence in the lower musculature.

CONCLUSION: With lower workloads, the BFR training protocols produced improvements in isometrics and isokinetic strength, work, power, and EMG that were comparable to those of the HIGH group across the trained and untrained limbs. The magnitude and limb-specific patterns varied across isometric, isokinetic, and EMG variables, but …

Modern Water And Sediment Transport Patterns In Alluvial Ridge Basins Of The Rio Grande Delta, South Texas, Usa, Waqid Nabi

Theses and Dissertations

Alluvial ridge (AR) basins are shallow, marine-influenced depressions within river deltas, yet their flow and sediment dynamics remain poorly understood. This study examines hydrodynamics and sediment transport patterns in the Bahia Grande Complex, which are AR basins of the Rio Grande Delta, using tilt current meters, water-level and turbidity loggers, and suspended and bed-sediment sampling. The AR basins function as wind-dominated, microtidal environments, where pre-existing basin geometry and hydrodynamic forcings control water flow and sediment distribution patterns. Seasonal wind patterns and storms modulate water levels and flow connectivity. Substrate patterns reflect frequent resuspension in the shallow northern basin, maintaining coarse …

Career Readiness Competencies Among First-Generation Undecided Students And Their Parents In The United States, Nicole M. Kotlan, Evan W. Faidley

Journal of Global Education and Research

The purpose of this study was to investigate the relationship between first-generation status and the value of career readiness competencies of first-generation undecided students (n = 106) and their parents (n = 178), explored through social cognitive career theory and Bourdieu’s theory of habitus and social and cultural capital. A non-experimental design using a non-random sample revealed, through an independent t-test, statistically significant differences in global/intercultural competency among students based on their first-generation status. The results of a multiple linear regression analysis suggest that parents’ values are associated with students’ values and professionalism/work ethic; however, no relationship was …

Uncertainty Estimation For Graph-Based Learning In Digital Pathology, Saba Heidari Gheshlaghi, Nasim Yahyasoltani, Masoud Ganji

Computer Science Faculty Research and Publications

High-resolution digital scans of pathology slides, known as whole slide images (WSIs), have detailed spatial and contextual information for diagnosing cancer. However, the classification performance of WSIs by deep learning models is typically compromised by data with a different distribution, known as out-of-distribution (OOD), resulting in unreliable predictions. Therefore, having a reliable predictive uncertainty estimation is crucial for clinical adoption. This article comprehensively studies graph-based uncertainty estimation for WSI classification using two cutting-edge graph neural network (GNN) architectures: 1) graph attention networks (GAT); and 2) GraphSAGE. In this work, we introduce the first unified multihead GNN framework that leverages GraphSAGE …

Evaluation Of Ramp Instead Of Forage During Grain Adaptation And Different Sorghum Varieties On Enteric Methane Production From Cattle, Jack T. Fort

Department of Animal Science: Dissertations, Theses, and Student Research

Two experiments were conducted to evaluate the use of RAMP (Cargill Corn Milling, Blair, Nebraska) compared with traditional forage-based adaptations on methane (CH₄) and carbon dioxide (CO₂) emissions, performance, and carcass characteristics. Experiment 1, 64 yearling British × Continental steers (initial BW = 423 ± 6 kg) were adapted using 100% RAMP (RAMP) or a traditional forage diet (CON; 43% forage) before transitioning 22 d to a common finishing diet containing 65.6% steam-flaked corn. Emissions were measured in paired replications using a two-chamber indirect calorimetry barn. During adaptation RAMP did not affect CH₄ production (g/d; …

High-Risk Medications In Pediatric Dentistry: Patterns, Outcomes, And Clinical Implications, Yilei Liu, Kawtar Zouaidi, Colin C Hubbard, Muhammad F Walji, Matthew R Cooke, Donald B Rindal, Kristin N Ray, Elsbeth Kalenderian, Katie J Suda

Faculty, Staff and Student Publications

Background: High-risk medications such as opioids and benzodiazepines are frequently prescribed in pediatric dental care, yet their prescribing patterns and associated adverse outcomes remain poorly understood. The aim of this study was to determine the extent of such prescribing to pediatric patients and factors associated with adverse outcomes.

Methods: MarketScan data for patients younger than 18 years with a dental visit from 2014 through 2019 were analyzed. High-risk medications included benzodiazepines, barbiturates, and opioids. Composite outcomes included hospitalization, emergency department visit, or urgent care visit within 7 days after the dental visit. Opioid-attributable outcomes included opioid-related overdose within 7 days …

Perceived Utility Of Genetic Carrier Screening In A Diverse Patient Population, Jack A Colleran, Meagan Choates, Syed Hashmi, Brittanie Shelton, Aranza Gonzalez Cendejas, Angela Haynes Burgess, Blair K Stevens

Faculty, Staff and Student Publications

Current reproductive guidelines call for offering expanded carrier screening (ECS) for genetic conditions. Currently available panels can include screening for carrier status of tens to hundreds of autosomal recessive and/or X-linked conditions. Clinical utility is based on alterations to reproductive decision-making, but study cohorts supporting the utility of ECS largely consist of individuals of European ancestry who are highly educated, of high income, and who often receive preconception counseling. There is a lack of research on the views of patients from diverse backgrounds. Therefore, we aimed to assess and compare perceptions of the utility of ECS and targeted carrier screening …

Kras Inhibition Activates An Actionable Cd24 "Do Not Eat Me" Signal In Pancreatic Cancer, Yongkun Wei, Minghui Liu, Er-Yen Yen, Jun Yao, Zhenzhen Xun, Phuoc T Nguyen, Xiaofei Wang, Zecheng Yang, Abdelrahman Yousef, Dean Pan, Yanqing Jin, Ching-Fei Li, Madelaine S Theardy, Jangho Park, Yiming Cai, Mitsunobu Takeda, Matthew Vasquez, Elizabeth M Park, David H Peng, Yong Zhou, Hong Zhao, Timothy P Heffernan, Andrea Viale, Huamin Wang, Stephanie S Watowich, Han Liang, Dan Zhao, Ronald A Depinho, Wantong Yao, Haoqiang Ying

Faculty, Staff and Student Publications

KRASG12C inhibitors (G12Ci) have produced encouraging, albeit modest and transient, clinical benefit in pancreatic ductal adenocarcinoma (PDAC). Identifying and targeting resistance mechanisms to G12Ci treatment is therefore crucial. To better understand the function of KRASG12C and possible G12Ci bypass mechanisms, we developed an autochthonous KRASG12C-driven PDAC model. Compared to the classical KRASG12D PDAC model, the G12C model exhibits slower tumor growth, yet similar histopathological and molecular features. Aligned with clinical experience, G12Ci treatment of KRASG12C tumors produced modest impact despite stimulating a ‘hot’ tumor immune microenvironment. Immunoprofiling revealed that CD24, a ‘don’t eat me’ signal, is significantly upregulated on cancer …

Author Correction: Evidence For Improved Dna Repair In The Long-Lived Bowhead Whale, Denis Firsanov, Max Zacher, Xiao Tian, Todd L Sformo, Yang Zhao, Gregory Tombline, J Yuyang Lu, Zhizhong Zheng, Luigi Perelli, Enrico Gurreri, Li Zhang, Jing Guo, Anatoly Korotkov, Valentin Volobaev, Seyed Ali Biashad, Zhihui Zhang, Johanna Heid, Alexander Y Maslov, Shixiang Sun, Zhuoer Wu, Jonathan Gigas, Eric C Hillpot, John C Martinez, Minseon Lee, Alyssa Williams, Abbey Gilman, Nicholas Hamilton, Ekaterina Strelkova, Ena Haseljic, Avnee Patel, Maggie E Straight, Nalani Miller, Julia Ablaeva, Lok Ming Tam, Chloé Couderc, Michael R Hoopmann, Robert L Moritz, Shingo Fujii, Amandine Pelletier, Dan J Hayman, Hongrui Liu, Yuxuan Cai, Anthony K L Leung, Zhengdong Zhang, C Bradley Nelson, Lisa M Abegglen, Joshua D Schiffman, Vadim N Gladyshev, Carlo C Maley, Mauro Modesti, Giannicola Genovese, Mirre J P Simons, Jan Vijg, Andrei Seluanov, Vera Gorbunova

Faculty, Staff and Student Publications

No abstract provided.

Evidence For Improved Dna Repair In The Long-Lived Bowhead Whale, Denis Firsanov, Max Zacher, Xiao Tian, Todd L Sformo, Yang Zhao, Gregory Tombline, J Yuyang Lu, Zhizhong Zheng, Luigi Perelli, Enrico Gurreri, Li Zhang, Jing Guo, Anatoly Korotkov, Valentin Volobaev, Seyed Ali Biashad, Zhihui Zhang, Johanna Heid, Alexander Y Maslov, Shixiang Sun, Zhuoer Wu, Jonathan Gigas, Eric C Hillpot, John C Martinez, Minseon Lee, Alyssa Williams, Abbey Gilman, Nicholas Hamilton, Ekaterina Strelkova, Ena Haseljic, Avnee Patel, Maggie E Straight, Nalani Miller, Julia Ablaeva, Lok Ming Tam, Chloé Couderc, Michael R Hoopmann, Robert L Moritz, Shingo Fujii, Amandine Pelletier, Dan J Hayman, Hongrui Liu, Yuxuan Cai, Anthony K L Leung, Zhengdong Zhang, C Bradley Nelson, Lisa M Abegglen, Joshua D Schiffman, Vadim N Gladyshev, Carlo C Maley, Mauro Modesti, Giannicola Genovese, Mirre J P Simons, Jan Vijg, Andrei Seluanov, Vera Gorbunova

Faculty, Staff and Student Publications

At more than 200 years, the maximum lifespan of the bowhead whale exceeds that of all other mammals. The bowhead is also the second-largest animal on Earth1, reaching over 80,000 kg. Despite its very large number of cells and long lifespan, the bowhead is not highly cancer-prone, an incongruity termed Peto’s paradox2. Here, to understand the mechanisms that underlie the cancer resistance of the bowhead whale, we examined the number of oncogenic hits required for malignant transformation of whale primary fibroblasts. Unexpectedly, bowhead whale fibroblasts required fewer oncogenic hits to undergo malignant transformation than human fibroblasts. …

Bayesian Integrated Learning Of Longitudinal Dose-Response Relationships Via Decentralized Clinical Trials, Jingyi Zhang, Tuo Wang, Yongming Qu, Fangrong Yan, Suyu Liu, Ruitao Lin

Faculty, Staff and Student Publications

Decentralized clinical trials (DCTs) extend trial activities beyond traditional sites, enhancing access, convenience, efficiency, and result generalizability. They are particularly promising for chronic conditions like diabetes and obesity, which require longer study durations to evaluate drug effects. However, decentralized data collection raises concerns about increased variability and potential biases. This paper presents a novel Bayesian integrated learning procedure to analyze dose-response relationships using longitudinal data from a phase II DCT that combines centralized and decentralized data collection. We generalize a parametric exponential decay model to handle mixed data sources and apply Bayesian spike-and-slab priors to address biases and uncertainties from …