Digital Commons Network^™

The Prospector, December 2, 2025, Utep Student Publications

The Prospector

No abstract provided.

Hif-2-Dependent Regulation Of Pthrp And Paraneoplastic Hypercalcemia In Aggressive Clear-Cell Renal Cell Carcinoma, Arijit Mal, Bingqing Xie, Zane Gray, Charlotte Small, Susmita G Ramanand, Yunpeng Gao, Vanina Toffessi Tcheuyap, Sashi Debnath, Alana Christie, Jeffrey Miyata, Brooklyn Jackson, Hua Zhong, Boning Gao, Jay Lohrey, Naim M Maalouf, Sangeetha M Reddy, John D Minna, Ivan Pedrosa, Xiankai Sun, Ram S Mani, Payal Kapur, James Brugarolas

Faculty, Staff and Student Publications

Renal cell carcinoma (RCC) patients with hypercalcemia (HC) have worse outcomes. HC often involves PTHrP, and the role of HIF-2 is incompletely understood. Leveraging RCC tumorgraft (TG) models of HC, which were characterized by tumor cell autonomous inflamatory/immune signatures, we show that HIF-2 inhibition with PT2399 frequently normalized calcium, downregulated circulating PTHrP and reduced HIF-2 binding to the PTHLH (PTHrP) promoter. Likely contributing to the selective induction of PTHrP in a subset of HIF-2-dependent tumors, the PTHLH locus was generally more accessible in TG(HC). However, PTHLH chromatin accessibility was grossly unaffected by PT2399, unlike elsewhere (including EPO locus in a …

Line Transect Surveys And Initial Estimates Of Abundance For Sea Turtles In Biscayne National Park, Florida., Kathryn C. Price

All HCAS Student Capstones, Theses, and Dissertations

The loggerhead (Caretta caretta) and green (Chelonia mydas) turtle are two species of marine megafauna that have suffered abundance declines due to increased anthropogenic pressures. Assessing the distribution and abundance of sea turtles is essential for conserving and managing these imperiled species; however, assessing sea turtle populations poses difficulties due to the sea turtles’ highly migratory nature. Distance sampling surveys are extensively used to study populations of wide-ranging species. In this study, vessel-based line transect survey data collected throughout 2024 were used to estimate overall and seasonal sea turtle abundances and distribution throughout Biscayne National Park, …

Netherton Syndrome: A Systematic Review Of The Challenges Of Diagnosis And Treatment, Maximus S. Reese, Ryan Nguyen, Noor Chughtai, Philip J. Haynos, Salma Alkhatib, Shantanu Amin, Ethan Speer, Jared Nichols

Student Publications

Netherton syndrome is an autosomal recessive genodermatosis caused by biallelic mutations in the SPINK5 gene, a gene that codes for lymphoepithelial Kazal-type-related inhibitor 1 (LEKT1) protein. This disorder is characterized by erythroderma, ichthyosis, hair shaft abnormalities, and immune dysregulation. While there is increasing research and recognition of Netherton syndrome, much remains unknown, with limited knowledge of the history, manifestations, and responses to therapies. The purpose of this study was to review case reports of Netherton’s to draw conclusions from patient demographics, symptoms, treatment, and outcomes. A systematic review of 30 case reports and clinical studies on Netherton syndrome was conducted, …

Bridging Modalities: Enhancing Multimodal Sentiment Analysis For Social Media Networks, Misbah Ul Hoque

LSU Doctoral Dissertations

Social media platforms like X (formerly Twitter) serve as rich sources of textual and visual information, making multimodal sentiment analysis essential for understanding complex human emotions. This dissertation aims to advance multimodal sentiment analysis by improving the semantic alignment and fusion of textual and visual features, thereby enabling more accurate and context-aware sentiment interpretation of social media content.

To address challenges in multimodal integration, this work proposes two complementary MSA approaches. The first approach introduces a similarity-based multi-layer attention neural network (SiMANN) that enhances modality integration through cosine-based similarity fusion and modality-specific attention to emphasize salient features in text and …

Statistically Significant Association Does Not Imply Improvement In Prediction Of Clinical Outcomes, Shu Jiang, Bernard A Rosner, Graham A Colditz

2020-Current year OA Pubs

UNLABELLED: In the current landscape of clinical studies, the concept of statistically significant association is often mixed up with the expectation of improved prediction performance. We discuss the two concepts, association and prediction, and present the epidemiologic principles and statistical constructs that underlie the discrepancy between statistically significant associations and the rationale for their lack of impact on improving prediction in terms of discrimination. This issue is illustrated using an existing breast cancer dataset. The concept of statistically significant association should not be mixed up with the expectation of improved discrimination performance. Although some markers may not markedly improve discrimination, …

The Legal Position Of The Religious Communities In The Republic Of Macedonia, Jovan Jonovski

Occasional Papers on Religion in Eastern Europe

The territory of the modern Republic of Macedonia (official name as of recently is Republic of North Macedonia) has historically been exposed to Judaism, Eastern and Western Christianity, Islam, and later to Protestantism. In the People’s /Socialist Republic of Macedonia, the religious communities were kept out of public life and suppressed. The government favored the Macedonian Orthodox Church for strengthening the Macedonian national consciousness. The Republic of Macedonia is a self-declared secular multi-confessional state. The article covers the history of the religious landscape as well as the legal framework and practices of the state toward the Churches, faith communities, and …

Religious Communication In Ukraine's Media Space As Factor In The Formation Of Confessional Identity, Oleh Sokolovskyi, Dmytro Garaschuk

Occasional Papers on Religion in Eastern Europe

This article presents a comprehensive study within religious studies of religious periodicals in Ukraine from the early 1990s to the present. It attempts to analyze the dynamics of the emergence and transformation of printed religious mass media in the context of the democratization of social life, changes in the information environment, and the development of civil society. It is noted that religious periodicals occupy a special place within the media landscape, since they perform not only the function of conveying information but also tasks of catechesis, spiritual-educational ministry, the formation of value orientations, and the preservation of cultural-historical heritage.

The …

Orthodoxy, Culture And Language: Alaska In Russia’S Religious Diplomacy Of The 21st Century, Oleksandr Lukyanenko

Occasional Papers on Religion in Eastern Europe

The article is devoted to the analysis of the religious factor of the Russian foreign diplomacy in the light of Vladimir Putin’s high-profile visit to Alaska n August 15, 2025. The paper studies a special place of Alaska in the historical imagination of Russian political and church discourse. The status of this particular territory in Russian state worldview – the former “Russian America” – is indicative: it refers to the idea of an unfinished imperial legacy. The research doesn’t touch a main event that included a meeting with US President Donald Trump but an off-schedule meeting with Archbishop Alexei (Trader) …

Protests, Epistemic Injustice, And The Movement For Black Lives, Sofia De Ferrari

PSU McNair Scholars Online Journal

Epistemic injustice provides a powerful perspective for understanding media narratives of the Movement for Black Lives (#BlackLivesMatter). To understand the media coverage, I draw on Foucauldian theories and critical race theory, as well as accounts of hermeneutical and recognition injustice, which show how “truth” emerges as a product of knowledge/power/resistance. Special attention is given to the question of violence: what is violent and what isn’t? Who gets to decide? What are the consequences? Media narratives favor the status quo and delegitimize social movements which challenge it. This is achieved by prioritizing the voices of officials and law enforcement in coverage …

“Mysterium Tremendum Et Fascinans”: Melian’S And Lúthien’S Numinosity, Alexandra (Oleksandra) Filonenko

Mythopoeic Society Seminar Proceedings

At the heart of all the positive changes in Middle-earth, and at the starting point for undoing the great evil wrought by male characters (divine or otherwise), are two female characters: Melian the Maia and her daughter Lúthien. They form a kind of mythological complex of mother and daughter goddesses, similar to that of Demeter and Persephone. Melian, as a static, maternal figure, forms a sacred centre of Beleriand to which all in need of protection gravitate, while Lúthien, representing a dynamic principle, can be considered the greatest hero of Tolkien’s Legendarium, performing feats unmatched by any male character. Yet …

Grendel's Mother Talks Back: Contemporary Women's Mythopoeic Revisions, Anna Smol

Mythopoeic Society Seminar Proceedings

"Grendel's Mother Talks Back: Contemporary Women's Mythopoeic Revisions" examines how twenty-first-century feminist adaptations and translations examine the significance and point of view of Grendel's Mother, a character from the Old English poem Beowulf. In contrast to past views of Beowulf, especially in J.R.R. Tolkien's influential essay on the poem, these women writers and scholars argue for the central role of Grendel's Mother and give voice to her story. The paper discusses the main features of these adaptations, covering topics of narrative voice, borderlands, violence, and motherhood, and generally questions the concept of monstrosity as applied to Grendel's Mother. The paper …

Sex, The Body, And Learning Gender: Demons In The World Of The Five Gods, Erin E. Mcbrien

Mythopoeic Society Seminar Proceedings

“Sex, the Body, and Learning Gender” analyzes the relationship between the physical body, sexual orientation, and gender as characterized within Lois McMaster Bujold’s World of the Five Gods series, with a particular emphasis on her Penric and Desdemona novellas. Using the framework of Bussey and Bandura’s social learning theory, and a close reading of Bujold’s text, this paper explores how the demonic characters within this series are an example of gender as a learned concept rather than a biological imperative. This is further developed by examining how the demonic characters both imprint on and contrast against the more societally-bound sorcerers …

Belief After The Death Of King Arthur: Lev Grossman’S Postsecular Portrayal Of Nimue In The Bright Sword, Liz Busby

Mythopoeic Society Seminar Proceedings

This paper explores Lev Grossman’s 2024 novel The Bright Sword as a postsecular retelling of the Arthurian legend, focusing on the character of Nimue. Unlike previous modern portrayals that align Nimue with pagan traditions in opposition to Christianity, Grossman presents her as both a practitioner of magic and a sincere Christian believer. Through this duality, Nimue embodies the tensions and contradictions of faith in a postmodern age, where belief persists amid doubt, historical trauma, and religious pluralism. Drawing on postsecular theory, the paper situates Grossman’s work within a broader literary tradition that includes Marion Zimmer Bradley’s The Mists of Avalon …

Upper-Body Post-Activation Performance Enhancement In Mma Athletes: Load-Dependent Effects Across Multiple Explosive Tasks, Jan Strawiński, Dariusz T. Skalski, Magdalena Prończuk, Kinga Łosińska, Ewelina Lulińska, Miłosz Drozd, Maciej Kostrzewa, Adam Maszczyk, Robert K. Roczniok

Baltic Journal of Health and Physical Activity

Background: Post-activation performance enhancement (PAPE) has become a recognized method for acutely improving explosive output, particularly relevant to upper-body performance in combat sports. Objective: This study aimed to evaluate the effects of bench press conditioning activities (CAs) at different intensities (50 %, 65 %, and 80 % 1RM) on upper-body explosive performance in mixed martial arts (MMA) athletes, with emphasis on training status. Methods: Twenty-nine male MMA athletes were divided into intermediate (n = 14) and advanced (n = 15) groups. Each participant completed three CA sessions followed by a 4-minute recovery and then performed a plyometric push-up …

The Internet Of Hate: Comparing The Nature, Harms, And Regulatory Challenges Of Online And Offline Hate Speech, Alexander Brown

Georgia Journal of International & Comparative Law

No abstract provided.

Fundamental Fairness Guides The Supreme Court's Criminal Justice Decisions In The 2024-2025 Term, Sharon R. Fairley

ConLawNOW

During the 2024-2025 term, the Supreme Court decided fifteen cases related to the criminal justice system. These cases were brought by criminal defendants seeking post-conviction relief and civil litigants seeking redress for governmental harms arising out of criminal processes. Remarkably, two-thirds of the cases resulted in decisions favoring defendants or civil litigants opposing the government. This Article argues that the pro-defendant outcomes from this term are consistent with a recent trend in the Court’s decisions favoring defendants in these types of cases. The pro-defendant outcomes from the 2024-2025 term generally resulted from the less conservative justices aligning with the liberal …

Tax Trends, Harry Z. Garian

Tax Adviser

No abstract provided.

Tax Practice Management, Sidney Kess

Tax Adviser

No abstract provided.

Tax Clinic, Thomas Parsons

Tax Adviser

No abstract provided.

Professions At Work: The Work Of The Aicpa Tax Division, Herbert Finkston

Tax Adviser

No abstract provided.

Audits, Business Abuses And Disciplinary Action, William H. Smith

Tax Adviser

No abstract provided.

Structural Characterization Of Precambrian Basement Using Magnetic Method In Ago-Iwoye, Southwestern Nigeria, Hamid T. Oladunjoye, Nurudeen K. Olasunkanmi, Omolara A. Adenuga, Sofiat A. Adekoya, Bolarinwa J. Adekoya, Williams T. Ifarajimi

Sultan Qaboos University Journal For Science

Structural characterization was conducted in some parts of Ago-Iwoye to better understand the basement formation for engineering, environmental, and mining studies. The ground magnetic geophysical method was employed to analyze the variations and orientation of the magnetic properties within the basement. Ten (10) magnetic profile lines were established, each approximately 200 m in length. Data were collected using a GEMS GSM 19T proton precession magnetometer and its accessories, measuring the total magnetic field intensity with a precision of about ± 0.1 nT. The residual magnetic intensity was calculated from the total magnetic intensity by deducting the International Geomagnetic Reference Field …

Groundwater Exploration Using Electrical Resistivity Method: A Case Study Of Ga-Gata, Ilorin, Nigeria, A. K. Olawuyi, V. O Oluwole

Sultan Qaboos University Journal For Science

Twenty-five Schlumberger Vertical Electrical Soundings and six Horizontal Resistivity Profiling for groundwater exploration at Ga-Gata along Ajase-ipo road, Ilorin in Kwara State, Nigeria were carried out. The aim was to identify the different subsurface geoelectric layers and the aquifer units. Using the usual method of curve matching with the Orellana-Mooney Master curves and 1-D forward modeling with WinResist 1.0TM software, between three to five lithologic units were identified. These include: the topsoil, the lateritic layer, the weathered layer, the fractured layer and the fresh bedrock. The weathered and fractured basement constitutes the main aquifer unit. The depth to the bedrock …

The Impact Of Cumulative Career Experience Of Internal Control Managers On Firms' Efficiency In Different Information Environments, Inkyung Yoon, Hansol Lee, Dongjoon Choi

Economic and Business Review

This study investigates the effect of internal control (IC) managers' cumulative career experience on the operational efficiency of Korean listed firms between 2018 and 2020. Building on the premise that managers with extensive experience positively influence ICs and the internal information environment, this study hypothesises that cumulative career experience of an IC manager is also positively associated with a firm's operational efficiency. To empirically assess efficiency, this study applies data envelopment analysis (DEA), a nonparametric technique that evaluates relative efficiency based on multiple input and output measures. The results suggest that IC managers with greater cumulative experience significantly enhance a …

Star Storm On The Horizon, Bee Bishop

The Prairie Light Review

No abstract provided.

Bard Observer Vol. 24, No. 3 (December 2025), Bard College

Bard Observer, 2020 - 2029

No abstract provided.

Fully Integrated Slippage Detection System For Lower Limb Amputees, Christopher E. Miglio

Master's Theses

Lower limb amputees face significant challenges in maintaining a proper prosthetic fit, as improper fit can lead to slippage at the limb-socket interface, resulting in discomfort, pressure sores, and long-term musculoskeletal complications. To address this issue, a fully integrated slippage detection system was developed to monitor an amputee’s daily activities and slippage occurrences to understand their prosthetic fit over time. The system consists of a prosthetic sock embedded with Interlink 406 flexible piezoresistive force-sensing resistors (FSRs). The sock, worn directly on the residual limb, continuously measures pressure at the limb-socket interface. Sensor data from six FSRs is sampled at approximately …

Aged 539 Graduate Internship Report - Mt. Whitney High School, Tule Marie Cardoza

Agricultural Education: Graduate Internship Reports

This project reviewed a high school agricultural education program with an emphasis on agricultural mechanics. Program strengths and needs were identified through curriculum and resource evaluation. Based on the findings, a budget was developed to support equipment, materials, and instructional improvements for the ag mechanics program.

Aged 539 Graduate Internship Report - Monache High School, Karli Hampton

Agricultural Education: Graduate Internship Reports

The goal of this project was to create a clear and organized Introduction to Agricultural Mechanics curriculum that gives students a strong starting point within the Monache High School agricultural mechanics pathway. The curriculum now provides students with consistent expectations related to safety, basic tool use, and appropriate behavior in a shop setting that directly supports the structure and expectations of the Monache Agricultural Mechanics Program.