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Measurement Of Luminous Intensity Distribution For Film And Television Led Light Sources And Its Simulation Research In Game Engines, Jingyi Suo, Baihong Lu, Che Qu Dec 2025

Measurement Of Luminous Intensity Distribution For Film And Television Led Light Sources And Its Simulation Research In Game Engines, Jingyi Suo, Baihong Lu, Che Qu

Journal of System Simulation

Abstract: To address the issues of mismatched photometric characteristics between light sources in virtual environments and real-world lighting during film and television lighting design and lighting preview using game engines, a testing solution for measuring the luminous intensity distribution for film and television LED light sources was proposed, building upon existing luminaire light intensity distribution testing systems. Based on the obtained data, a light source calibration process was constructed in the UE5 to correctly simulate the photometric characteristics of light sources in the virtual environment. Simulation results have shown that the calibration process can accurately and efficiently reproduce the …

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Diskursus Kriminalisasi Pemidanaan Terhadap Pemberi Gratifikasi, Muhammad Fatahillah Akbar Dec 2025

Diskursus Kriminalisasi Pemidanaan Terhadap Pemberi Gratifikasi, Muhammad Fatahillah Akbar

Jurnal Hukum & Pembangunan

This article aims to examine the legal basis to prosecute gratifiers in Indonesian Corruption Justice System. Samin Tan as the giver of gratification to Eni Maulani Saragih had been acquitted by the Corruption Court of Jakarta Decision Number 37/Pid.Sus-TPK/2021/PN.Jkt.Pst on 30th August 2021. Then, the Cassation to Supreme Court had also been rejected by Supreme Court Decision Number 2205 K/Pid.sus/2022 on 9th June, 2022. Hence, Samin Tan stays acquitted. The decision majorly focuses on the “absence” of law which criminalizes gratifiers or gratification givers. Therefore, this article elaborates how similar cases shall be handled in the future. In …

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Estimating Prey Capture Attempts And Activity Costs In Foraging Emperor Penguins (Aptenodytes Forsteri) Using Integrated Biologging Data, Taylor Rose Azizeh Dec 2025

Estimating Prey Capture Attempts And Activity Costs In Foraging Emperor Penguins (Aptenodytes Forsteri) Using Integrated Biologging Data, Taylor Rose Azizeh

Master's Theses

To forage efficiently in patchy and unpredictable prey landscapes, marine predators must optimize energy intake while minimizing costs. Central place foragers like emperor penguins face greater energetic constraints during demanding periods of high investment like chick-rearing. I used high-resolution tri-axial acceleration, depth, and GPS data from 25 birds from two feeding seasons (2019 and 2022) to quantify prey capture attempts and a proxy for energy expenditure (overall dynamic body acceleration; ODBA) across dive types (epipelagic, mesopelagic, benthic), phases (descent, bottom, ascent), and over time at-sea. While prey capture attempts per minute did not differ when looking across dive types alone, …

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Hospital–Medicare Advantage Vertical Integration And Cardiopulmonary Care In Integrated Hospitals, Geronimo Bejarano, Meehir N. Dixit, Alexander P. Philips, Karen E. Joynt Maddox, Meredith B. Rosenthal, Amal Trivedi, David J. Meyers Dec 2025

Hospital–Medicare Advantage Vertical Integration And Cardiopulmonary Care In Integrated Hospitals, Geronimo Bejarano, Meehir N. Dixit, Alexander P. Philips, Karen E. Joynt Maddox, Meredith B. Rosenthal, Amal Trivedi, David J. Meyers

2020-Current year OA Pubs

No abstract provided.

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Satellite-Mediated Quantum Clock Synchronization: Towards Precise Timing At A Global Scale, Sage B. Ducoing Dec 2025

Satellite-Mediated Quantum Clock Synchronization: Towards Precise Timing At A Global Scale, Sage B. Ducoing

LSU Doctoral Dissertations

Accurate timekeeping is essential for scientific and technological advancements, particularly in areas of communication, networking, navigation, and high precision measurements. While many methods of time resolution are already established using classical resources, they fail to combine high precision outcomes with large-scale implementations. Additionally, numerous quantum networking architectures using satellite-assisted methods have demonstrated quantum communication on scales exceeding ground-based methods. For these reasons, we propose the use of a time synchronization method by which pairs of highly time-correlated photons are exchanged between clocks on satellites and clocks on Earth, al- lowing users to reconstruct the time offsets between their clocks. This …

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Power-Efficient Speech Detection And Transcription Utilizing Cascaded Visual Triggers And Sensor Fusion, Jon Hurwitz, Yaaseen Mahomed Dec 2025

Power-Efficient Speech Detection And Transcription Utilizing Cascaded Visual Triggers And Sensor Fusion, Jon Hurwitz, Yaaseen Mahomed

Defensive Publications Series

Voice interaction is often the primary input modality for wearable electronic devices, such as augmented reality (AR) glasses. However, effective interaction via a voice interface can be difficult in certain common scenarios such as noisy environments, quiet environments where the wearer cannot provide audible spoken input, etc. This disclosure describes techniques that enable adaptive, multi-modal speech-to-text transcription on smart glasses using sensor fusion. The smart glasses include microphones (e.g., a microphone array), a vibration sensor (e.g., in the nose bridge), and low-power cameras that have the wearer’s lips in the field of view. Data streams from these sensors are combined …

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Correcting Display Deformations Using A Thermoelectric Cooler Matrix, Kunwoo Park, Sean Terbeek, Yusuf Mohsinally, Harrison Pham Dec 2025

Correcting Display Deformations Using A Thermoelectric Cooler Matrix, Kunwoo Park, Sean Terbeek, Yusuf Mohsinally, Harrison Pham

Defensive Publications Series

Temperature variations in the context in which a lenticular display is deployed can result in non-uniform expansion across the display, leading to visual distortion. This disclosure describes techniques to counter non-uniform thermal expansion of a lenticular display due to temperature gradients or other environmental factors. Per the techniques, individual elements of the display are each coupled to a strain gauge and a thermoelectric cooler (TEC). Strains (thermally induced displacements) across the display are provided as input to a microcontroller unit (MCU). The MCU coordinates the matrix of TECs such that individual TECs heat or cool their regions of the display …

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Deterministic Workflow Generation From Ai-Generated Prototypes, Wai Tai Dec 2025

Deterministic Workflow Generation From Ai-Generated Prototypes, Wai Tai

Defensive Publications Series

Generative artificial intelligence (AI) tools can accelerate workflow prototyping but remain inherently unreliable — the same prompt can yield inconsistent, incomplete, or broken outputs. Proposed herein is an innovation that bridges the gap between AI prototyping and production-grade automation by capturing validated “golden outputs,” extracting them into reusable briefs ("golden briefs"), and regenerating workflows deterministically through template-aware automation. Layered validation, including schema compliance, simulation with golden inputs, and regression testing ensures that every workflow produced is correct, reproducible, and ready for production deployment.

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A Review Of Machine Learning Methods In Energy Management System, Mays Sattar Al-Fatllah, Zaipatimah Ali, Aidil Azwin Zainul Abidin Dec 2025

A Review Of Machine Learning Methods In Energy Management System, Mays Sattar Al-Fatllah, Zaipatimah Ali, Aidil Azwin Zainul Abidin

Almaaqal Journal of Sustainability and Emerging Technology

Traditional energy sources are vital for energizing residences and industries. Nonetheless, they meet considerable obstacles, such as deteriorating infrastructure, ecological decline, resource exhaustion, price fluctuations, and a disparity between real-time demand and supply. Conversely, renewable energy sources offer cleaner and more sustainable energy sources. Renewable energy mitigates the pollution caused by carbon and greenhouse gas emissions in traditional power systems. Incorporating renewable energy into a power system needs an efficient management system to keep stability and improve power use. Modern energy management systems (EMS) face a significant challenge in controlling renewable and non-renewable energy sources. The challenges encompass intermittent and …

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Machine Learning Framework For Automatic Classification Of Nano-Seismic Signals Preceding Earthquakes, Ghada Ali, Ali G. Hafez, Sayed Hasaneen, Hamed Nofel, Nabeel Al-Atwan, Ahmed Mohamed Dec 2025

Machine Learning Framework For Automatic Classification Of Nano-Seismic Signals Preceding Earthquakes, Ghada Ali, Ali G. Hafez, Sayed Hasaneen, Hamed Nofel, Nabeel Al-Atwan, Ahmed Mohamed

Almaaqal Journal of Sustainability and Emerging Technology

Nano-seismicity preceding earthquakes has many applications in fault prediction, in structure health monitoring, and in enhancing fault and source parameter determination. Not all earthquakes are preceded by these precursors; therefore, there is a need to identify P-wave arrivals that are preceded by these nano signals, which will eliminate errors in P-wave arrival timing. The current work introduces topologies capable of automatically categorizing the arrivals with nano-seismic precursors. The proposed methods are trained on datasets extracted from stations belonging to Egyptian National Seismic Network (ENSN). These records contain both P-wave arrivals preceded by such nano precursors and other records without these …

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Logging-While-Drilling Azimuthal Electromagnetic Measurements For High-Resistivity Coal Seams, Zhao Weina, Zheng Dongfang, Ai Weiping, Xie Xia Dec 2025

Logging-While-Drilling Azimuthal Electromagnetic Measurements For High-Resistivity Coal Seams, Zhao Weina, Zheng Dongfang, Ai Weiping, Xie Xia

Coal Geology & Exploration

Objective and Method To determine the boundary detection capability of logging-while-drilling (LWD) electromagnetic azimuthal measurements for high-resistivity coal mines, this study simulated geosignal responses under varying operating frequencies, transmitter-receiver coil spacing conditions, and formation resistivity values. Then, key parameters for boundary detection for high-resistivity coal seams were optimized. Accordingly, this study proposed design schemes for LWD instruments with short (< 80 inches) and long (approximately 240 inches) transmitter-receiver coil spacing for short-distance (2.032 m) and long-distance (6.096 m) detection, respectively. Results and Conclusions LWD electromagnetic azimuthal measurements exhibit a significantly decreased depth of detection (DOD) in high-resistivity coal seams compared to that in low-resistivity hydrocarbon reservoirs. Consequently, the existing methods for selecting the operating frequency and transmitter-receiver coil spacing are …

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Current Status And Future Trend Of Research On Underground Borehole Measurement Technology For Coal Mines, Chen Long, Yang Dongdong, Li Quanxin, Chu Zhiwei, Zhang Jiguan, Chen Xiang Dec 2025

Current Status And Future Trend Of Research On Underground Borehole Measurement Technology For Coal Mines, Chen Long, Yang Dongdong, Li Quanxin, Chu Zhiwei, Zhang Jiguan, Chen Xiang

Coal Geology & Exploration

Background Underground borehole measurement emerges as a core technology for the safe production of coal mines. Its multi-parameter measurements, data accuracy, data transmission rate, and reliability directly influence the timeliness of early warning for disasters, the operating stability of instruments, the accuracy of borehole assessment, and the scientific rigor of intelligent decision-making under complex deep geological conditions. Advances So far, the measurement while drilling (MWD) and post-drilling borehole visualization techniques have developed into a diversified technological system. Specifically, the MWD technique has achieved a leap from wireline to wireless transmission, obviating the reliance on wireline drill rods in traditional measurement …

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Key Technical Difficulties, Challenges, And Prospects Of Geologic Co2 Sequestration In Saline Aquifers, Wei Hengfei, Shi Junjie, Nie Xiaodong, Fang Jie, Chen Jing, Zhao Yue, Sun Dawei, Li Xin, Zhang Yong, Guo Pei Dec 2025

Key Technical Difficulties, Challenges, And Prospects Of Geologic Co2 Sequestration In Saline Aquifers, Wei Hengfei, Shi Junjie, Nie Xiaodong, Fang Jie, Chen Jing, Zhao Yue, Sun Dawei, Li Xin, Zhang Yong, Guo Pei

Coal Geology & Exploration

Background and Method Carbon capture and storage (CCS) technology represents the primary technical direction for large-scale carbon emission reduction. Among various CCS techniques, geologic CO2 sequestration in saline aquifers holds great potential, establishing it as a major technique for future carbon storage. Based on a review of the current status of research on global geologic CO2 sequestration in saline aquifers, this study comprehensively analyzed the technical difficulties, challenges, and prospects of this technology, focusing on the dilemma of the application of this technology under complex geological conditions in China. Results and Conclusions A huge gap in both the …

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Self-Adaptive Inverse Wavefield Transform And Derived Pseudo-Wavefield Characteristics Under Roadway-Borehole Observation Of Transient Electromagnetic Data, Fan Kerui, Guo Jianlei, Wang Ruoyu, Zhuang Ming, Fan Fangze, Xu Sheng, Zhao Wentao Dec 2025

Self-Adaptive Inverse Wavefield Transform And Derived Pseudo-Wavefield Characteristics Under Roadway-Borehole Observation Of Transient Electromagnetic Data, Fan Kerui, Guo Jianlei, Wang Ruoyu, Zhuang Ming, Fan Fangze, Xu Sheng, Zhao Wentao

Coal Geology & Exploration

Objective To address the challenge of detecting aquifers outside the roadway excavation contour, this study combined the close-range detection via roadway-borehole transient electromagnetic (TEM) method with the wavefield transform. This will help simultaneously receive detection signals in front of the mining face and outside the roadway excavation contour while also highlighting the boundary information of aquifers. Moreover, to obtain a pseudo-wavefield featuring both reasonable kinematic characteristics and high sensitivity to changes in the electrical structures of strata, this study proposed a self-adaptive algorithm of inverse wavefield transform, thereby improving the accuracy and efficiency of the inverse wavefield transform of roadway-borehole …

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Performance And Migration Path Tracing Of Magnetic Grouts For Fractured Rock Masses, Shang Hongbo, Wang Hao, Wang Xiaodong, Qiao Wei, Wang Tiantian, Sun Junqing, Sun Jie Dec 2025

Performance And Migration Path Tracing Of Magnetic Grouts For Fractured Rock Masses, Shang Hongbo, Wang Hao, Wang Xiaodong, Qiao Wei, Wang Tiantian, Sun Junqing, Sun Jie

Coal Geology & Exploration

Objective For coal mining areas in the middle reaches of the Yellow River basin, sealing mining-induced fractures via grouting serves as an effective approach to preventing water inrushes from coal seam roofs while also protecting groundwater resources. However, accurately identifying the migration paths of grouts remains a bottleneck for the further application of grouting modification technology to fractured rock masses. Methods This study investigated a coal mine threatened by both water inrushes from the coal seam roof and a short supply of water resources within the Jurassic coalfield in the middle reaches of the Yellow River basin, focusing on the …

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An Automated Attitude Control Method For The Rotary Steerable System And Its Validation Through Hardware-In-The-Loop Simulation, Zhang Nan, Ren Bai’An, Li Fei, Liu Ziqi, Lyu Fangxing Dec 2025

An Automated Attitude Control Method For The Rotary Steerable System And Its Validation Through Hardware-In-The-Loop Simulation, Zhang Nan, Ren Bai’An, Li Fei, Liu Ziqi, Lyu Fangxing

Coal Geology & Exploration

Objective The traditional manual control mode of a rotary steerable system (RSS) faces challenges, including response delay and low control efficiency. To address these challenges, this study proposed a closed-loop automated attitude control method for the RSS and verified its effectiveness through hardware-in-loop (HIL) simulation. Methods This study focuses on the drilling process of a point-the-bit RSS. In the case of deviations between measured and target attitudes, the control parameters were calculated based on the deviation signals using a closed-loop controller, driving the RSS actuator to conduct trajectory correction. Afterward, the actual attitude was yielded and then entered the input …

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Synthesis Of Biogenic Silver Nanoparticles From Apricot Kernel Extracts For The Colorimetric Determination Of Gold, Ayça Gi̇rgi̇n, Hi̇lal Akbiyik, Buse Tuğba Zaman, Omid Nejati, Ayça Bal Öztürk, Gülten Çeti̇n, Sezgi̇n Bakirdere Dec 2025

Synthesis Of Biogenic Silver Nanoparticles From Apricot Kernel Extracts For The Colorimetric Determination Of Gold, Ayça Gi̇rgi̇n, Hi̇lal Akbiyik, Buse Tuğba Zaman, Omid Nejati, Ayça Bal Öztürk, Gülten Çeti̇n, Sezgi̇n Bakirdere

Turkish Journal of Chemistry

Gold is abundant in nature, however, precise and reliable analytical methods for its detection are required stemming from its increasing prevalence in environmental, biological, and industrial systems, as well as the growing interest in understanding its function in living organisms and its effects on human health. This study investigates the use of biogenically synthesized silver nanoparticles (AgNPs) for the preconcentration and determination of gold ions prior to determination by UV-Vis spectrophotometry. AgNPs were synthesized by reducing silver nitrate through the use of an apricot kernel extract as both reducer and stabilizer agent. The colloidal yellowish AgNPs interacted with gold ions, …

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Effects Of Video Game Type On Cognitive Performance And Brain Functional Connectivity: A Longitudinal Eeg Study, Jingqing Lu, Ruifang Cui, Lijun Jiang, Chenyu Mu, Weiyi Ma, Diankun Gong, Dezhong Yao Dec 2025

Effects Of Video Game Type On Cognitive Performance And Brain Functional Connectivity: A Longitudinal Eeg Study, Jingqing Lu, Ruifang Cui, Lijun Jiang, Chenyu Mu, Weiyi Ma, Diankun Gong, Dezhong Yao

General Human Environmental Sciences Faculty Publications and Presentations

Background: Previous research has shown that video gaming experience is associated with changes in cognitive and perceptual functions as well as neural structure and function. However, how the different types of video games differentially influence cognitive function and neuroplasticity remains unclear. Methods: In this 30-week longitudinal study, participants were randomly assigned to an action video game group or a strategy card game group. Behavioral assessments and resting-state electroencephalography (EEG) recordings were administered at six time points to evaluate changes in attention, working memory, executive function, and their neural correlates. Results: Both groups showed significant improvements in multiple cognitive tasks, but …

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Responsible Ai For Text Classification: A Neutrosophic Approach Combining Classical Models And Bert, Nabil M. Abdel-Aziz, Mahmoud Ibrahim Dec 2025

Responsible Ai For Text Classification: A Neutrosophic Approach Combining Classical Models And Bert, Nabil M. Abdel-Aziz, Mahmoud Ibrahim

Neutrosophic Sets and Systems

No abstract provided.

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Supersaturation Effect And Its Characterization In Gas-Rich Intervals Of Deep Coal Seams, Zhou Lihong, Li Yong, Ding Rong, Li Yun, Li Yongzhou, Kong Jintao Dec 2025

Supersaturation Effect And Its Characterization In Gas-Rich Intervals Of Deep Coal Seams, Zhou Lihong, Li Yong, Ding Rong, Li Yun, Li Yongzhou, Kong Jintao

Coal Geology & Exploration

Objective and Method High free gas content serves as a key factor controlling the enrichment and high productivity of deep coalbed methane (CBM). However, its direct determination is challenging, making the accurate identification of free gas-rich coal seam intervals a core scientific issue for efficient exploration and recovery of CBM. This study investigated the Daning-Jixian block (also referred to as the Daji Block) within the Ordos Basin. Based on analyses and tests of the gas content, coal macrolithotype, physical properties, and log responses of cores collected from representative wells through pressure-retained coring, this study systematically assessed the vertical heterogeneity of …

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Physical Simulation Experiments On 4d Visualization Of Dynamic Methane Diffusion And Adsorption In Low-Porosity And Low-Permeability Coals, Liu Tong, Jiao Baizhuo, Lin Baiquan, Sang Shuxun, Yang Wei, Liu Shiqi, Liu Ting, Li He, Yang Mingxing Dec 2025

Physical Simulation Experiments On 4d Visualization Of Dynamic Methane Diffusion And Adsorption In Low-Porosity And Low-Permeability Coals, Liu Tong, Jiao Baizhuo, Lin Baiquan, Sang Shuxun, Yang Wei, Liu Shiqi, Liu Ting, Li He, Yang Mingxing

Coal Geology & Exploration

Objective and Method The diffusivity of methane (CH4) in coal seams significantly influences the surface extraction of coalbed methane (CBM) and underground gas drainage. However, the visualized characterization of the diffusion and migration processes of CH4 in coals remains challenging. To address this issue, this study systematically demonstrated the similarity between krypton (Kr) and CH4 in their adsorption and diffusion behavior in coals. Utilizing Kr—a gas with high X-ray attenuation—as a tracer substitute for CH4, this study achieved the transparent observation of the dynamic gas migration process in low-porosity, low-permeability, and heterogeneous coals using …

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Organically-Bound Forms Of Alkali And Alkaline Earth Metals In High-Alkali Coals And Their Geological Indications, Wang Xiaoling, Wang Shaoqing, Zhao Yungang, Mu Ruifeng, Shao Yan Dec 2025

Organically-Bound Forms Of Alkali And Alkaline Earth Metals In High-Alkali Coals And Their Geological Indications, Wang Xiaoling, Wang Shaoqing, Zhao Yungang, Mu Ruifeng, Shao Yan

Coal Geology & Exploration

Objective and Method Alkali and alkaline earth metals (AAEMs) in coals adversely affect coal processing and utilization. Among the AAEMs, water-soluble and mineral-hosted metals can be largely removed through water washing, flotation, and heavy liquid separation, while organically-bound AAEMs are difficult to eliminate. In this study, high-alkali coal samples with varying vitrinite/inertinite ratios (V/Is) collected from the Zhundong coalfield in Xinjiang were selected to investigate the organically-bound forms of AAEMs. Through sequential chemical extraction, combined with experimental techniques such as 23Na cross-polarization magic-angle spinning nuclear magnetic resonance (23Na CP/MAS NMR) and transmission electron microscopy-energy dispersive …

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On Performance Analysis Of A Neutrosophic Bipolar Fuzzy And Texture-Based Model For Covid-19 Detection From Chest X-Rays, Sanjayprabu S, Senthil Kumar L, Santhakumari R, Mareeswari R, Ajithkumar R Dec 2025

On Performance Analysis Of A Neutrosophic Bipolar Fuzzy And Texture-Based Model For Covid-19 Detection From Chest X-Rays, Sanjayprabu S, Senthil Kumar L, Santhakumari R, Mareeswari R, Ajithkumar R

Neutrosophic Sets and Systems

No abstract provided.

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Neutrosophic-Based Feature Set (Nbfs) For Brain Tumor Detection Using Glcm Features And Knn Classifier On Mri Images, S. Gowri, V. M. Vijayalakshmi Dec 2025

Neutrosophic-Based Feature Set (Nbfs) For Brain Tumor Detection Using Glcm Features And Knn Classifier On Mri Images, S. Gowri, V. M. Vijayalakshmi

Neutrosophic Sets and Systems

No abstract provided.

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Process Activities Of A Neutrosophic-Based Smart Simulation Framework For Islamic Sacred Rituals, Nabil M. Abdelaziz, Mohamad S. Al-Thenyan Dec 2025

Process Activities Of A Neutrosophic-Based Smart Simulation Framework For Islamic Sacred Rituals, Nabil M. Abdelaziz, Mohamad S. Al-Thenyan

Neutrosophic Sets and Systems

No abstract provided.

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Neutrosophic‑Enhanced Cephalometric Analysis With Improved Diagnostic Accuracy For Egyptian Population, Nagham Ahmed Abdelmegeed, Amal F. Abdel-Gawad Dec 2025

Neutrosophic‑Enhanced Cephalometric Analysis With Improved Diagnostic Accuracy For Egyptian Population, Nagham Ahmed Abdelmegeed, Amal F. Abdel-Gawad

Neutrosophic Sets and Systems

No abstract provided.

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Neutrosophic Probability And Measure For Resilient Supply Chain Management Under Indeterminacy, Mohamed Ismail, Esraa Kamal Dec 2025

Neutrosophic Probability And Measure For Resilient Supply Chain Management Under Indeterminacy, Mohamed Ismail, Esraa Kamal

Neutrosophic Sets and Systems

No abstract provided.

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Neutrosophic State Learning For High-Stakes Systems Using A Dynamic Triplet Model Of Support Contradiction And Uncertainty, Alaa Hassan And, Reda Ahmed Dec 2025

Neutrosophic State Learning For High-Stakes Systems Using A Dynamic Triplet Model Of Support Contradiction And Uncertainty, Alaa Hassan And, Reda Ahmed

Neutrosophic Sets and Systems

No abstract provided.

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Neutrosophic Α-Discounted Cognitive Mapping For Financial Distress Prediction: Evidence From Saudi Emerging Markets, Mohanned H. Alharbi Dec 2025

Neutrosophic Α-Discounted Cognitive Mapping For Financial Distress Prediction: Evidence From Saudi Emerging Markets, Mohanned H. Alharbi

Neutrosophic Sets and Systems

No abstract provided.

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Α-Glycosidase Activity Of Novel Coumarin–Triazole–Coumarin Dyads, Ersi̇n Şi̇ri̇n, Esra Sevi̇mli̇, Gökçe Seyhan, Burak Barut, Yunus Kaya, Baybars Köksoy Dec 2025

Α-Glycosidase Activity Of Novel Coumarin–Triazole–Coumarin Dyads, Ersi̇n Şi̇ri̇n, Esra Sevi̇mli̇, Gökçe Seyhan, Burak Barut, Yunus Kaya, Baybars Köksoy

Turkish Journal of Chemistry

Novel coumarin–triazole–coumarin dyads were synthesized and characterized, and their α-glycosidase inhibitory activities were evaluated spectrophotometrically. Compound 4e exhibited the most pronounced inhibitory effect, with an IC50 value of 38.98 ± 0.77 μM. The IC50 values for 4d and 4a were 93.55 ± 1.70 μM and 95.04 ± 3.55 μM, respectively. The Lineweaver–Burk plot showed that 4e inhibited α-glycosidase in a mixed type. In addition, the Ki value obtained from the Dixon plot was 19.95 ± 0.15 μM for α-glycosidase.

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