Digital Commons Network^™

Establishing Demographic-Based Normative Values For Neurofilament Light Chain And Glial Fibrillary Acidic Protein In Serum And Plasma Samples, Tyler L Borko, Salim Chahin, Et Al.

2020-Current year OA Pubs

BACKGROUND: Interpretation of neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) levels in blood requires reference ranges from healthy cohorts, accounting for demographic features.

OBJECTIVE: To compare serum and plasma NfL and GFAP in healthy individuals, accounting for age, sex, and body mass index (BMI).

METHODS: Adolescents through older adults were recruited at Colorado community events and a senior clinic. A neurologist reviewed self-reported medical histories. Paired serum and EDTA plasma samples were assayed using the Quanterix SR-X Simoa Neuro 4-Plex. Log-linear models estimated percent change per year of age, per BMI unit, and sex ratios. GFAP used …

Immortalization And Characterization Of Schwann Cell Lines Derived From Nf1-Associated Cutaneous Neurofibromas, Hua Li, Angela Hirbe, Et Al.

2020-Current year OA Pubs

Neurofibromatosis type 1 (NF1) is an autosomal dominant condition in which patients are heterozygous for a disruptive pathogenic variant in the NF1 gene. The most characteristic feature of the condition NF1 is the neurofibroma, a benign, multi-cellular tumor which initiates when a cell of the Schwann cell lineage gains a somatic pathogenic variant of the other NF1 allele. Neurofibromas developing at nerve termini in the skin are termed "cutaneous" neurofibromas (cNFs), while those developing within larger nerves are termed "plexiform." Most patients develop cNFs beginning in late childhood or early adulthood, continuing throughout life at variable rates. Some patients may …

Implementing The Lung Donor (Lundon) Acceptability Score In U.S. Donor Management And Transplant Decision-Making: A Multi-Aim, Mixed-Methods Protocol, Nikki E. Rossetti, Su-Hsin Chang, Yan Yan, Graham Jaensch-Frie, Charles R. Liu, Nahom Y. Seyoum, Meghna Katta, Arvind Kumar, Zhizhou Yang, Christian Oncken, Christy Hamilton, Kyle Stumbaugh, Brendan Heiden, Sarah Peskoe, Varun Puri, Et Al.

2020-Current year OA Pubs

BACKGROUND: Despite advances in transplantation science, a persistent shortage of donor lungs continues to limit access to life-saving lung transplants. The Lung Donor (LUNDON) Acceptability Score is a validated tool that predicts donor lung utilization and post-transplant recipient outcomes, but integration into practice remains limited. This study will evaluate determinants of LUNDON score adoption, its impact on clinical decision-making, and develop tools to support its implementation.

METHODS: This is a multi-aim mixed-methods pre-implementation study that will be conducted across U.S. Organ Procurement Organizations (OPOs) and lung transplant centers. Aim 1 will identify barriers and facilitators of LUNDON score adoption through …

Rethinking Library Opac: From Siloed Retrieval To Ai And Ml-Driven Discovery Using Fastapi And Mysql, Sukumar Mandal

Library Philosophy and Practice (e-journal)

The paper explores integration methods between MySQL and FastAPI to develop dynamic Online Public Access Catalog services including functionalities for modern libraries and information centers. It addresses evolving user expectations by replacing rigid keyword-based search models with adaptive, intelligent discovery experiences that prioritize search relevance. The goal involves transforming traditional library retrieval tools into contextual discovery platforms that effectively understand specific user intent and complex needs. The prototype was created on Ubuntu in a customized Python environment. It uses FastAPI to manage asynchronous API calls and MySQL to store bibliographic data. SQLAlchemy abstracts the database layer, and Pydantic validates data. …

From Digital Skills To Digital Ventures: Exploring The Influence Of Digital Competence On Infopreneurship Intentions Of Library And Information Science Students In Nigerian Polytechnics, Uwaebuka Wisdom Madu Dr., Stephen Adekunle Ajayi Dr

Library Philosophy and Practice (e-journal)

The focus of this study was to investigate the influence of digital competence on infopreneurship intention among Library and Information Science (LIS) students in federal polytechnics in South-West Nigeria, a context characterized by high graduate unemployment and rapid digital transformation. Guided by the Theory of Planned Behaviour and Eshet-Alkalai's Digital Literacy Model, a descriptive survey design was employed. The population comprised 638 final-year LIS students across four federal polytechnics, with a sample of 468 selected through multi-stage sampling. A validated questionnaire with a reliability coefficient of 0.828 was used for data collection. 388 responses amounting to 82.9% response rate was …

Cross-Domain Antimicrobial Resistance In Poultry Farming: A One Health Assessment Of Antimicrobial Use And Multidrug Resistance In Kiambu County, Kenya, Ann Kangai Munene, Peter Muiruri Mwangi, Lilly Caroline Bebora, Christine Minoo Mbindyo, John Muthini Maingi

All Peer-Reviewed Publications

Background and Aim: Antimicrobial resistance (AMR) has emerged as a major One Health threat driven by inappropriate antimicrobial use (AMU) in humans, animals, and the environment. Poultry production is recognized as a key reservoir of antimicrobial-resistant bacteria, yet few studies in Kenya examine AMU and AMR across interconnected human–animal–environment domains. This study assessed AMU patterns among poultry farmers in Kiambu County and characterized phenotypic resistance in Escherichia coli and Enterococcus spp. isolated from humans, chickens, and chicken environments. Materials and Methods: A cross-sectional study was conducted from May to September 2024, involving 102 poultry farms. Farm demographics and AMU data …

Oligonychus Trichardti (Acari: Tetranychidae) Associated With Urochloa Grasses In Kenya: An Integrative Taxonomic Approach, Paula Espitia-Buitrago, Claudia Perea, Lavender A. Odhiambo, Rosa N. Jauregui, Frank Chidawanyika

All Peer-Reviewed Publications

Spider mites represent a significant constraint to improved forage grass adoption in East Africa, particularly affecting Urochloa cultivars that are crucial for addressing the region’s 40% livestock feed gap. This study employed an integrative taxonomic approach combining morphological and molecular analyses to identify a spider mite species infesting Urochloa interspecific grasses in Kenya. A colony of 80 spider mites was established from symptomatic Urochloa hybrid cv. Cayman plants collected from Mbita Point, Kenya, showing characteristic foliar chlorosis and necrotic spots. Morphological examination of 46 slide-mounted specimens using Hoyer’s medium revealed consistent morphotypical features characteristic of Oligonychus (Reckiella) trichardti Meyer, 1974. …

Effects Of Temperature On The Life-History Traits Of Myzus Persicae And Its Efficiency In Transmitting Potato Virus Y (Pvy) In Potato Crops, Bonoukpoè M. Sokame, Henri E. Tonnang, Heidy Gamarra, Pablo Carhuapoma, Jan Kreuze, Leah R. Johnson, Ali Arab, Peter A. Armbruster, Oswaldo C. Villena

All Peer-Reviewed Publications

Aphids are highly sensitive to temperature changes and play a crucial role in transmitting plant viruses, accounting for the transmission of more than 50% of viruses that cause disease in crops. Among them, Myzus persicae is a major global pest, affecting over 400 plant species and transmitting more than 100 plant viruses, including potato virus Y (PVY), which poses a severe threat to potato crops. This study examines how temperature influences the life-history traits of M. persicae and its efficiency in transmitting PVY. Our research revealed that temperature significantly affects developmental duration, survival, and fecundity of M. persicae. The aphids …

Exploring Slow-Release Plasma Nitrogen Nano-Fertilizer For Improved Maize Production And Nutrient Use Efficiency, Stewart Kyebogola, Richard Onwonga, Stella Kabiri, Onesimus Semalulu, Swidiq Mugerwa, Russell Shelley Yost, Samuel Ikendi, Dennis Beesigamukama, Julius Opio, Godfrey Sseruwu

All Peer-Reviewed Publications

The use of nitrogen (N) fertilizer in maize production is constrained by scarcity, low use efficiency, and high costs. Plasma technology presents a more environmentally friendly nitrogen source (PN). When incorporated into nanocellulose composites to control fertilizer release (NPN), they improve N supply and mitigate environmental risks, thereby optimizing benefits. However, the productivity of NPN relative to urea and its nanoform (NU) remains unexplored. Screenhouse and field experiments were conducted twice on maize using five fertilizer treatments: control, urea, PN, NU, and NPN. All treatments were applied once at 66 kg N ha^-1 and replicated four times. Maize cultivated …

Directing Young Actors, Mitchell Whelan

Theses : Honours

This reflective practice case study examines the studio environment of a small ensemble of female actors aged 16-19, in the rehearsal of a one-act play. Performing arts researchers working in youth spaces commonly adhere to conventions of ethnodrama and facilitate a process in which participants contribute personal stories as performance material. The present paper uses a published text (Slut by Patricia Cornelius) to position participants as actors, rather than devisors who must conjure original material. Through critical reflection, the project assesses the impact of developing performance material slowly while also making time for socialisation between castmates. Drawing on my repertoire …

The Travelling Dancer: The Exploration Of Strength And Conditioning And Lifestyle Strategies To Mitigate The Risk Of Posterior Ankle Impingement Whilst Dancing Abroad, Emma Tucker

Theses : Honours

Ballet dancers commonly experience posterior ankle impingement (PAI), and while there is research regarding the biomechanical risk factors for PAI in ballet dancers, and mitigation and rehabilitation strategies for this type of injury, there is little research conducted surrounding further barriers posed by international travel. This study investigated the implications of international travel on the risk mitigation and rehabilitation of posterior ankle impingement in ballet dancers, exploring barriers posed by international travel to regular strength and conditioning and lifestyle practices. Three ballet dancers and two physiotherapists were interviewed and shared their lived experience with, or treating, posterior ankle impingement in …

Experimental Investigation Into The Effects Of Air Staging On Fouling In A Fixed-Bed Biomass Combustor, Akram Elsebaie

Theses: Doctorates and Masters

Biomass offers significant potential as a sustainable and renewable substitute for fossil fuels in energy generation, playing a critical role in the reduction of global warming. However, despite its environmental benefits, biomass combustion faces persistent operational challenges, particularly fouling, which reduces efficiency and increases maintenance costs. Although fouling mechanisms have been studied in various combustion systems, there is limited research which addresses its formation and behaviour in fixed-bed biomass combustors under different air staging conditions. This research investigates fouling behaviour in a counter-current combustor, focusing on the influence of design (secondary air location), operational (air staging flowrates between the primary …

Detecting Habitat Use Of Three Endemic Freshwater Fish Of Far Southwestern Australia, Paige Rhiannon Wilson

Theses: Doctorates and Masters

The wetland ecosystems of far southwestern Australia face multiple threats including land clearing, historical cattle grazing, changed hydrology, extensive groundwater extraction, and changed fire regimes. Each is exacerbated by a drying climate, and together they provide a significant challenge to the on-going survival of the freshwater fish in this region particularly fish that are endemic, range restricted, and therefore, more likely to be more vulnerable. This study focuses on three such species: Galaxiella munda, Galaxiella nigrostriata and Lepidogalaxias salamandroides, the latter two of which are known to aestivate.

In order to make conservation decisions regarding management of wetlands for …

The Matusiflute: Exploring Intercultural Collaboration Through Timbral Dízi Emulation Within An Australian-Chinese Orchestral Performance Setting, Gabriel Mcmahon

Theses: Doctorates and Masters

This research investigates how the Matusiflute can potentially promote intercultural Sino Western collaboration within solo, chamber and orchestral settings by consciously applying technical and stylistic codes attributed to the dízi (traverse Chinese bamboo flute). Using an autoethnographic approach, I reflect on my engagement with the dízi, its morphology, timbre and stylistic interpretation, and how my pedagogical flute context impacted this approach. These learnings were then applied to the Matusiflute through two premiere performances of a commissioned intercultural work by Nicholas Ng, The Secret of the Golden Flower (2024) for Matusiflute and Chinese Orchestra. The latter being performed in a solo …

An Investigation Into The Mechanisms, Barriers, Degree And Sphere Of Risk Influence In Corporate Security, Nicola Lockhart

Theses: Doctorates and Masters

This study investigates the sphere of corporate security risk influence within organisations, addressing the conceptual and practical ambiguity surrounding the activity’s capacity to shape organisational decisions, behaviours, and risk priorities. While corporate security’s protective role is widely recognised, its broader organisational risk influence remains under-theorised. The study defines the sphere of risk influence as the range of organisational stakeholders and environments with which the corporate security activity interacts, and within which it may engage, persuade, and mobilise action. This sphere is analytically constituted through the intersection of three dimensions: the mechanisms through which influence is attempted, the barriers that constrain …

Development Of Virtual Reality Learning Environments In Science To Engage Secondary Students In Hazardous Activities, Luke Spartalis

Theses: Doctorates and Masters

This research examines the need for change in including hazardous activities in education. As different learning technologies develop, platforms that retain authentic outcomes via virtual reality are needed. The main objective of this research is to examine the inclusion of Virtual Reality Learning Environments (VRLEs) to determine their value in areas that include hazardous conditions. The research considered the ways that VR tools could be optimised to support these activities, as well as considering the challenges of VRLE implementation. The study examined whether VRLE’s allowed for authentic experiences to sufficiently drive an acceptance of VR to complement existing teaching and …

Neurodevelopmental Outcomes After Posthemorrhagic Hydrocephalus Of Prematurity, Mekal S. Mathew, Rene Leal, Caroline L. Hanan, David J. Sun, Hasan K. Mubarak, Amelie D. Perrier, William E. Johnson, Micolette R. Mardik, Trevor R. Alwell, Christian Amezquita Contreras, Chance E. Hatfield, Peter H. Yang

Summer Research Program Abstracts

No abstract provided.

An Innovative, Interdisciplinary Intervention For Justice-Involved Emerging Adults, Courtney M. Holmes, Jeff Ciak, Marianne Lund, Zehra Sahin Ilkorkor, Grace Kye, Miguel King, Karen Akom, Sarah Jane Brubaker, Molly Hyer, Gary Cuddeback

Teaching and Supervision in Counseling

Interdisciplinary collaboration is an effective training model for counselors in training. As it is becoming increasingly likely that counselors will work in multidisciplinary teams post-graduation, engagement in clinical and research intervention teams is essential to promote learning. Benefits for counseling students include the development of self-efficacy, cultural humility, research skills, counseling skills, and interdisciplinary communication and collaboration skills. This article will discuss a federally funded, interdisciplinary intervention for justice-involved emerging adults that provides supported employment, trauma-informed mental health counseling, and peer support interventions. We will outline the interventions, structure of the project, as well as research and assessment outcomes. Future …

Interdisciplinary Collaborations In Schools: Lived Experiences Of School-Based Professionals, Karlesia Montague, Christina Barksdale, Crystal Speaks

Teaching and Supervision in Counseling

Collaboration is an ethical duty of school-based professionals and essential to addressing student needs and maximizing student success. This phenomenological qualitative research study explored the collaborative experiences between school counselors, school-based mental health counselors (SBMHCs), and school social workers. Through semi-structured interviews, we examined the experiences of 12 practicing school-based professionals. Using interpretative phenomenological analysis (IPA), we identified five group experiential themes: (a) it takes a village, (b) factors that influence collaboration, (c) advantages of teamwork, (d) challenges in collaborating, and (e) recommendations to improve collaborative practices. Implications for graduate training programs and recommendations for future research studies are discussed.

Discussion Of Living Through Capitalism, By James A. Chamberlain, James Chamberlain

Emancipations: A Journal of Critical Social Analysis

A discussion of Chamberlain's recent book, Living Through Capitalism: Resisting Devastation Through Communities of Life .

(En)Gendering Capacity: Neoliberalism, Empowerment, And Responsibility For Women In The Un’S Capacity Building Agenda, Sabrina K. Harris

Emancipations: A Journal of Critical Social Analysis

This article analyzes how the UN constructs capacity building as an element of its development agenda. It theorizes that the UN operates as a governmental actor, adopting and pursuing a political rationality of good governance, while also navigating structural limitations to its organizational authority in implementing this agenda imposed by the liberal international order. As such, this article argues capacity building emerges as a valuable technology of development for several reasons: firstly, it operates as an individual-level intervention, circumventing UN limitations on authority in mandating state action, and secondly, it is framed as demand-driven and empowering while delivering on the …

Organizing Identities: The Power Of Technofeudalism In A Precarious World – Milei, Youth Precarity, And Post-Partisan (“Anti-Everything”) Identities In Contemporary Argentina, Valeria Brusco

Emancipations: A Journal of Critical Social Analysis

This article explains why an anti-state radical-right agenda can become politically effective in contemporary Argentina by shifting the focus from ideology to the organization of identities. Drawing on survey evidence (ENCResPA, 7,130 online cases collected in 2022) and a corpus of anonymized semi-structured interviews with young people (2024–2025), I argue that Milei’s appeal is best understood as a form of negative politicization: a post-partisan stance built around rejection of mediation (parties, unions, experts, public institutions) and condensed moral narratives (“caste,” “cuts,” “freedom”). I identify an “Anti-Everything/Anti-Todo” identity as an electorally available and affectively intense orientation that travels efficiently …

The Present Interregnum: The Ultra-Right Revolution, María Pía Lara

Emancipations: A Journal of Critical Social Analysis

This paper deals with recent political consequences of presentism as conceptualized by the historian Francois Hartog. It clarifies how our experiences of time and history have enlarged the present and the past and have almost disappeared the future (except for catastrophic views). The consequences of these changes in the experiences reflect profound changes in expectations about the future, and how this regime of historicity allows people to become disoriented. They were moved into the margins of precarity. As a result, many of their views on politics find resonance redesigned by the distorted narratives of ultra-right leaders who blame those who …

Maximizing Online Intersession Enrollment Through Targeted Course Offerings, Heather S. Mcmillan, Charles D. Mcallister

Journal of the North American Management Society

Abstract

Online winter intersession courses have become an increasingly important strategy for universities seeking to support accelerated student progression while generating incremental tuition revenue. This study examines ten years of winter intersession enrollment data from a public, master’s-level comprehensive university in the Midwestern United States to identify course characteristics associated with higher student enrollment. Using 12,520 individual enrollment records, the analysis focuses on course type (general education versus major requirement), course classification (lower level, upper level, blended undergraduate/graduate, and graduate), and course discipline. A series of ANOVAs and Bonferroni post-hoc tests reveal significant differences in enrollment across these dimensions, with …

Organizational Pitfalls Of The Dual-Identity Leader, Yvonne Randolph, Asa Wilson

Journal of the North American Management Society

The dual-identity leader (D-IL) is an individual assigned to one job description yet is, in practice, fulfilling an additional position’s role. This secondary role is self-determined; has not been assigned yet is being allowed by those with governance and/or executive authority. Three case examples of the D-IL are presented and discussed as a problematic leadership configuration for an organization. The personal characteristics driving this approach are identified as a foundation for clarifying the organizational consequences of such an executive leader. Preventative and corrective tactics are discussed that eliminate or minimize the adverse impact of the D-IL’s organizational behavior.

Pluralism And Critique In A Renewed Environmental Anthropology, Helen Kopnina

Journal of Ecological Anthropology

Environmental anthropology has evolved from early ethnographic traditions that emphasized the interplay between culture and ecology to a field increasingly influenced by ideological perspectives across the political spectrum. Traditionally, anthropologists examined how human societies adapted to their environments through cultural practices, laying the groundwork for ecological anthropology. However, in recent decades, the field has increasingly been shaped by political and theoretical shifts that prioritize critiques of capitalism, colonialism, and environmental injustice—sometimes at the cost of empirical diversity and democratic debate. There are critiques of the broader trend in academia where intellectual discourse becomes dominated by elite-driven ideological conformity. Critics warn …

A Blood-Based Test For Colorectal Cancer Screening, Joshua Cullison

HCA Healthcare Journal of Medicine

Within the United States (US), colorectal cancer (CRC) remains the fourth most common malignancy and is responsible for over 50 000 deaths annually, second only to lung cancer in cancer mortality. Despite increased public awareness and increasing screening rates, the US remains far below the 80% screening mark set by the National Colorectal Cancer Roundtable at 59%. The addition of non-invasive blood-based tests for CRC screening could potentially increase screening rates and lower CRC deaths.

I performed a PubMed search using the search term “blood-based colorectal cancer screening.” I was particularly interested in articles that looked at Shield, which is …

Wilson’S Disease Psychosis In A Young Man With Autism Spectrum Disorder: A Case Report And Focus On Management, Landon C. Sowell, Barbara L. Gracious

HCA Healthcare Journal of Medicine

Introduction

Wilson's disease is a rare autosomal recessive disorder, affecting approximately 1 in 30 000 individuals and is characterized by abnormal copper accumulation in the body, primarily affecting the liver and brain. Psychiatric manifestations as a first presentation, particularly psychosis, are less commonly recognized resulting in failure to begin treatment early in the course of the disease. This case report highlights a patient that presented to the hospital with psychosis, who was later diagnosed with Wilson’s disease. This case underscores the importance of considering organic causes in first-episode psychosis.

Case Presentation

An 18-year-old man with a history of autism spectrum …

Masld-Induced Hyperammonemia With Atypical, Restricted Diffusion Pattern Suggesting Mixed Metabolic And Hypoxic-Anoxic Injury, Renu Thomas, Nhuchau Tiffany Nguyen, Daniel Bao, Jonathan Tang, Uzma Ali, Damon Cao

HCA Healthcare Journal of Medicine

Background

Hepatic encephalopathy is a common cause of altered mental status for patients with decompensated cirrhosis. Their conditions typically improve with high-dose laxatives; if not optimally treated, can develop neurologic sequelae like cerebral edema and herniation. In severe cases, despite normal systemic oxygenation, hyperammonemia may result in mixed restricted diffusion patterns that partially resemble those seen in hypoxic-anoxic brain injury.

Case Presentation

A 61-year-old woman with cirrhosis secondary to metabolic dysfunction-associated steatotic liver disease, scleroderma, and rheumatoid arthritis presented to the emergency room with altered mental status. She was admitted to the intensive care unit (ICU) and was intubated due …

Presentation Of Cutaneous Large B-Cell Lymphoma, Leg Type, Francisca I. Valenzuela, Michael R. Hohnadel

HCA Healthcare Journal of Medicine

A man over the age of 89 presented with 2 violaceous, ulcerated plaques on his left lower leg, which developed over a 4-month period following a fall. The patient reported the initial formation of a solitary lump, which gradually enlarged and began bleeding a few weeks before his clinic visit. A histological examination of 2 biopsy samples revealed a dermal proliferation of large, severely atypical lymphoid cells with mitotic figures. Immunohistochemistry showed positivity for CD20, Bcl2, Bcl6, and MUM1, with cytokeratin 20 (CK20) negativity and a high percentage (80%-90%) of C-MYC positivity, which was consistent with a primary cutaneous diffuse …