Digital Commons Network^™

Oil And The Macroeconomy: A Theory Of Sticky Oil Production, Sean Mcdermott

Economics Honors Theses

No abstract provided.

Eros, Again, Is Looking At Me Meltingly: The Role Of Vision In Archaic Lyric And Hellenistic Epigram, Ruth Patterson

Classical Studies Honors Theses

No abstract provided.

Administering Election Disputes, Rebecca Green

Faculty Publications

U.S. election administration has become supercharged with controversy. A process that should be mundane—casting and counting votes—has become the target of relentless litigation, much of which ends in non-merits rulings that risk perpetuating rather than resolving public concerns. The high volume of election litigation is costly, strains election officials, and risks eroding public trust in both elections and the courts. Recognizing the need to resolve election claims fairly and efficiently, Administering Election Disputes examines administrative remedies as an under-theorized alternative to judicial resolution. Increased use of well-designed administrative election dispute resolution (AEDR) could reduce pressure on courts, deliver faster and …

Transfusion In Transit: A Decade Of Prehospital Blood Transfusion In Pediatric Trauma, Krysta M Sutyak, Eunise C Chen, Lea Mock, Rudolfo Cabrera, Jeannette M Joly, Kuojen Tsao, Bryan A Cotton, David E Meyer, Charles S Cox, Kevin P Lally, Natalie A Drucker

The Brown Foundation: Institute of Molecular Medicine

Background: Prehospital blood transfusion improves mortality in adults, with limited evidence in children. This study describes prehospital blood transfusion in pediatric trauma patients and the impact on shock index, pediatric adjusted (SIPA).

Methods: This study is a retrospective cohort study of trauma patients younger than 18 years who received blood transfusions during helicopter transport to a Level 1 pediatric trauma center from 2011 to 2023. Primary outcome was change in SIPA at time of emergency department (ED) arrival with prehospital transfusion. Secondary subgroup analysis was performed based on transport origin.

Results: Of 137 patients, 58% (80 of 137 patients) were …

Affinity-Optimized Trop2 Antibodies Support Potent Antitumor Activity In Antibody-Drug Conjugates, Aiko Yamaguchi, Junping Hong, Leike Li, Kiyotaka Kobayashi, Chisato M Yamazaki, Summer Y Y Ha, Yasuaki Anami, Wei Xiong, Junquan Liu, Zhiqiang An, Ningyan Zhang, Kyoji Tsuchikama

The Brown Foundation: Institute of Molecular Medicine

Background: Trophoblast cell surface antigen 2 (TROP2) is frequently overexpressed in epithelial tumors and is associated with poor prognosis, making it an attractive therapeutic target. Antibody-drug conjugates (ADCs) directed against TROP2 show clinical benefit, but expression in normal tissues such as skin raises concerns about on-target, off-tumor toxicity. Strategies that improve antitumor efficacy without increasing toxicity are needed.

Methods: Using an in-house phage library, we identified and characterized a novel fully human monoclonal antibody recognizing a unique conformational epitope of TROP2 with reduced binding affinity. This antibody was engineered into homogeneous ADCs carrying auristatin and/or duocarmycin payloads. Comparative studies with …

Telomerase Knockout In Myeloid Cells Predisposes Mice To Foam Cell Formation, Dyslipidemia, Lung Fibrosis, And Cardiac Dysfunction, Zhanguo Gao, Yongmei Yu, David Wiggins, Eva M Sevick-Muraca, Mikhail G Kolonin

The Brown Foundation: Institute of Molecular Medicine

Aging-associated changes in myeloid cells are incompletely understood. One of the culprits of aging is the downregulation of the Tert gene coding for the catalytic subunit of telomerase. Studies of mouse models with Tert knockout (KO) in specific cells have revealed the importance of the telomere-independent noncanonical function of TERT in supporting mitochondrial metabolism and protection from cell senescence. To investigate the role of TERT in myeloid cells (MCs), we analyzed mice with Tert KO in the LysM+ lineage, indelibly labeled with membrane green fluorescent protein (mG). Macrophage numbers and properties in various organs were compared. Changes in the vasculature, …

Natural Language Generation In Healthcare: A Review Of Methods And Applications, Mengxian Lyu, Xiaohan Li, Ziyi Chen, Jinqian Pan, Cheng Peng, Sankalp Talankar, Yonghui Wu

Faculty, Staff and Student Publications

Objective: This study presents a systematic review of natural language generation (NLG) methods and applications in the medical domain, providing quantitative and qualitative analyses to answer four key research questions regarding methods, evaluation, applications, and challenges of NLG in healthcare.

Methods: We searched PubMed, ACM Digital Library, Web of Science, Science Direct, Scopus, Embase, and ACL Anthology for NLG-related studies in healthcare from 2018 to 2024. Out of 3,988 research articles, 113 met the inclusion criteria and were analyzed across data modality, model architecture, evaluation metrics, and application domain.

Results and conclusion: NLG in healthcare has grown substantially, with annual …

A New Standard: Default Inclusion Of Children In Clinical Trials, Megyn Gordon

Colorado Law Student Scholars

No abstract provided.

Stephen Stern And Steven Gimbel, Reclaiming The Wicked Son: Finding Judaism In Secular Jewish Philosophers, Ronald E. Hustwit Sr.

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

On The Hypostatic Structure Of The Holy Triad, Omar Fakhri

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

John Bishop And Ken Perszyk, God, Purpose, And Reality: A Euteleological Understanding Of Theism, Thomas Schärtl-Trendel

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Kierkegaard On Loving As Yourself, Dar Triffon-Reshef

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Divine Hiddenness: Evidence And Transcendence, Katelyn E. O’Dell

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Traumatic Brain Injury And Risk Of Early-Onset Dementia: A Population-Based Cohort Study, Aishwarya Saravanan, Katherine Giorgio, Natalia Lakomski, Andrea L C Schneider, Barbara A Olson-Bullis, Behnam Sabayan, James S Pankow, Paul S De Vries, Kristine Yaffe, Alexa Beiser, Abbas Dehghan, Elizabeth A Peterson, Rachel Zmora, John J Stephen, Denise Scholtens, Maxwell Mansolf, Lenore J Launer, Richard F Maclehose, Pamela L Lutsey, Norrina B Allen, Sanaz Sedaghat

Faculty, Staff and Student Publications

Introduction: We investigated the association between traumatic brain injury (TBI) and incidence of early-onset dementia (EOD) versus late-onset dementia (LOD).

Methods: We included 501,710 UK Biobank participants (average age 56.5). Over a median 13.6 years of follow-up, 836 developed EOD (before 65) and 8947 developed LOD (after 65). We estimated hazard ratios (HRs) for TBI's association with EOD and LOD using Cox proportional hazard models with TBI as a time-varying exposure and coefficient.

Results: TBI was associated with higher risk of both EOD (HR: 4.06 [95% confidence interval: 3.13, 5.26]) and LOD (HR: 2.51 [2.31, 2.72]. Among participants included in …

Unwelcomeness Reconsidered: Adapting Sexual Harassment Law In The Long Wake Of #Metoo, Collin Christner

Michigan Law Review

The federal cause of action for sexual harassment in employment grew out of Title VII’s prohibition of workplace sex discrimination. In many circuits, for sexual harassment claims to be actionable, the plaintiff must show they found the referenced conduct “unwelcome.” Commentators have criticized that requirement since its inception; nonetheless, it has been wielded by courts that are either resistant or reluctant to abandon it. “Unwelcomeness” (or lack of evidence thereof) has been used to permit swaths of inappropriate workplace conduct— enshrining old, sexist stereotypes into America’s employment regulations. This Note evaluates the current approach to the unwelcomeness requirement and proposes …

Performance Reviews In Project-Based Engineering Firms: Toward A More Holistic And Development-Oriented Approach, Xun He

Harrisburg University Dissertations and Theses

Performance reviews are widely used in engineering consulting firms to evaluate employee contributions and determine compensation and promotion decisions. However, research has shown that traditional review systems may overemphasize measurable technical results while overlooking collaboration, leadership, and innovation. In project-based engineering environments, where employees work across multiple teams and stakeholders, this structure may not fully reflect the nature of daily work. This qualitative phenomenological study explored how early-career engineers in project-based engineering consulting firms experienced performance review practices. Data were collected through semi-structured interviews with 15 engineers working in consulting firms. The study examined participants’ perceptions of fairness, completeness, and …

Mitochondria Dynamics In Microglia During Health, Inflammation, And Aging, Alicia Nicole Pietramale

Dartmouth College Ph.D Dissertations

Microglia continually surveil the brain, allowing for rapid detection of tissue damage or infection. Microglial metabolism is linked to tissue homeostasis, yet how mitochondria are subcellularly partitioned in microglia and dynamically reorganize during surveillance, injury responses, and phagocytic engulfment in the intact brain has remained unclear. In this dissertation, I combine intravital imaging, ultrastructural analyses, and metabolic and cytoskeletal markers to investigate how mitochondrial organization relates to microglial function across health, inflammation, and aging.

I first show that microglial processes diverge in their mitochondrial content, with some containing multiple mitochondria while others are completely void. This heterogeneous partitioning is conserved …

Beyond Algorithmic Equality, Tatiana Dancy

Northwestern Journal of Technology and Intellectual Property

Algorithms can predict the risk that a given offender will reoffend, on the basis of statistical observations about the relationship between certain attributes and proxies for criminal behavior (e.g., arrest or conviction). These predictions inform a range of decisions within the realm of criminal justice across the world, including sentencing, security classification, and parole. The variables that can increase an individual’s risk score, which are not widely publicized by those who develop or use risk tools, include financial stress, the criminality of friends or family, parental neglect, and experiences of domestic violence. In this way, algorithms may treat individuals as …

Measuring Legal Importance: From Case Citations To Linguistic Shifts, Bao Kham Chau

Northwestern Journal of Technology and Intellectual Property

This Article introduces a novel empirical method for measuring judicial importance beyond traditional metrics, such as citation counts, which often undervalue decisions that shape legal practice without generating extensive case law. Drawing on techniques from computational text analysis, it proposes linguistic shifts—systematic changes in the length, language, and structure of legal documents—as an alternative proxy for a judicial opinion’s legal significance.

The Article applies this method to a case study involving Blackboard, Inc. v. Desire2Learn, Inc., 574 F.3d 1371 (Fed. Cir. 2009), a Federal Circuit decision that has received relatively little attention under conventional citation-based measures. By programmatically analyzing …

Investigating Social Justice Implications Of Glyphosate Residues In Human Urine, Ananya Malhotra

Electronic Theses, Projects, and Dissertations

Background: Glyphosate, the nominal active ingredient in professional-grade Roundup weed and grass killer, is the most extensively used herbicide globally and in the United States (U.S. Environmental Protection Agency, 2020). An increasing level of concern has surfaced regarding its health consequences, particularly because of contamination of our food supplies. Recent research indicates distressing levels of detection of glyphosate in human blood and urine samples, revealing many instances of frequent human exposure (Conrad et al., 2017; Zhang et al., 2020).Most of the research about exposure is focused on agricultural workers or individuals living in close vicinity to agricultural lands.  Few …

2025 Martin Luther King, Jr. Keynote Lecture, Madiba Dennie

Villanova Law Review (1956 - )

No abstract provided.

Using State Sentencing Enhancements To Protect Journalists From Physical Assault, Anthony L. Fargo

Villanova Law Review (1956 - )

No abstract provided.

The View From The Bar: How Media Lawyers Perceive Their Work, Jonathan Peters, Skylar Bandoly

Villanova Law Review (1956 - )

No abstract provided.

Beyond A Protagonist Bias In Narrative Identity Research: Methods For Identifying Master Narratives In Interview Data, Andrew D. Coppens, Jayson Seaman, Cindy Hartman

Faculty Publications

This article advances a methodological shift in narrative identity research by addressing the field’s protagonist bias – the tendency to rely on first-person autobiographical accounts as the primary evidence for identifying cultural master narratives. We integrate Erikson’s psychosocial identity framework, Vygotsky’s “tool and result” methodological insight, and sociolinguistic approaches to narrative to develop a three-stage analytic logic: (1) identifying small-n narratives through scenes conveyed in discourse; (2) grouping these into Big-N narratives that cohere thematically across scenes (Tannen, 2007, 2008); and (3) assessing candidate master narratives using McLean and Syed’s (2016) five criteria. We demonstrate this approach through a case …

2026 April - Tennessee Monthly Climate Report, Tennessee Climate Office, East Tennessee State University

Tennessee Climate Office Monthly Reports

Hi All,

The main story of April 2026 was the hot and dry pattern that impacted Tennessee for most of the month and which was a continuation of this same pattern from March. Temperature anomalies across the state in April were slightly less than what we observed in March, but mean temperatures still ranged from 4-8°F above normal for April. Based on mean temperatures for the month, April 2026 was the warmest April on record in Knoxville’s 153-year weather history (beating out April 2017 by 0.2°F) and Nashville’s 152-year weather history (beating out April 2017 by 1.2°F). April 2026 was …

Voices | Risd Mfa Illustration Anthology 2026, Illustration Department, Illustration Mfa, Jaleen Grove, Minglu Du, Manuela Guzman, Rhea Hu, Faith Huang, Burcu Koleli, Airien Ludin, Ranran Ma, Mervin Miao, Nayyab Naveed, Rhea Pradeep, Pingfan Que, Mot Tuman, Skye Wang

Illustration MFA Anthologies

Illustration has often been dismissed as just a mechanical art, concerned with technique more than intellect. In fact, illustration is a theory of something’s essence, expressed and communicated visually. Craftsmanship – or a playful, mindful lack of it – is always in service to a concept and a purpose. The Masters theses summarized in this book are the result of struggles to give form to more than the tangible world. As writers and visualizers our students picture new meanings and refreshed experiences for the familiar; they define things previously unnamed.

Predicting Ventilation From Single Breathing Phase Non-Contrast Ct Using Swin Transformers, Yi-Kuan Liu, Hsu-Ting Kuo, Alaa Melek, Richard Castillo, Yevgeniy Vinogradskiy, Lili Zhao, Girish Nair, Edward Castillo

Department of Radiation Oncology Faculty Papers

BACKGROUND: Pulmonary ventilation imaging enables functional avoidance radiotherapy treatment plans by quantifying regional lung function. However, current clinical standards, such as 99𝑚Tc-based single-photon emission computed tomography (SPECT), rely on radioactive tracers, which can introduce imaging deposition artifacts. CT ventilation imaging (CTVI) methods based on both physical models and deep learning approaches currently require multiple CT images as input, such as the inhale/exhale phases of a 4DCT. While the theoretical foundation of physics-based CTVI is built on multi-phase information, the feasibility of single-phase deep learning CTV models has not been determined.

PURPOSE: While deep learning methods have predicted SPECT ventilation from …

Yield And Agronomic Response Of Maize (Zea Mays L.) To Municipal Organic Waste-Derived Biochar Amended With Vermiculite Or Gypsum And Npk Fertilization, Umar Kyari Wulgo, Samir Gamil Al-Solaimani, Khurram Shahzad, Mohamed Hassan Abd El-Wahed, Muhammad Imtiaz Rashid

Journal of King Abdulaziz University: Meteorology, Environment and Arid Land Agriculture

This study investigated the influence of biochar, produced from municipal organic waste, amended with either vermiculite or gypsum, and varying rates of NPK fertilizer on the agronomic response and yield performance of maize (Zea mays L.). A field experiment using a split-plot design was conducted across two growing seasons (2023 and 2024), with NPK fertilizer rates (150, 300, and 600 kg/ha) as the main plots and eight different biochar formulations as the subplots. The key agronomic parameters measured were fresh biomass, cob dry weight, shelling percentage, and harvest index. The findings revealed that vermiculite biochar and gypsum biochar …

The Acute Effects Of Heat Exposure On Cognitive Function, René Barbier

Presentations - 2026

Passive heat exposure negatively impacts: •Executive function & response inhibition •Attention & processing speed •Workplace productivity

Older adults face heightened vulnerability to cognitive decline under heat stress (Schlader et al., 2015).

Who is most affected?

•Outdoor & industrial workers •Athletes training in summer heat •First responders (firefighters, EMTs) •Older adults with thermoregulatory decline

San Antonio context: persistent summers, growing population, occupational health implications.

Slurry-As-A-Service: A Modest Proposal On Scalable Pluralistic Alignment For Nutrient Optimization, Rachel Hong, Yael Eiger, Jevan Hutson, Os Keyes, William Agnew

Articles

Pluralistic alignment has emerged as a promising approach for ensuring that large language models (LLMs) faithfully represent the diversity, nuance, and conflict inherent in human values. In this work, we study a high-stakes deployment context—mulching—where automated systems transform selected individuals into nutrientrich slurry for the dual purposes of food security and aesthetic population management. Building on recent pluralistic alignment frameworks, we introduce ValueMulch™, a reproducible training, deployment, and certification pipeline for aligning mulching models (MMs) to a wide range of community norms. Through a real-world testbed spanning 32 communities, we show that ValueMulch™ improves distributional agreement with community mulching preferences …