Digital Commons Network^™

The Interaction Of Adipose Derived Stem Cells And Breast Cancer, Natasha Cunningham, Ava O'Meara, Cathy L. Brougham

SURE Journal: Science Undergraduate Research Experience Journal

Introduction: Mesenchymal stem cells are adult stem cells capable of self-renewal and multilineage differentiation (Schweizer et al., 2015). Adipose derived stem cells have been used in breast reconstruction following surgical intervention in breast cancer patients. MicroRNAs have been linked to gene regulation essential in oncogenic, and tumour suppression as well as cell signalling pathways in BC.

Aim: To research the hypothesis of ADSCs and their therapeutic properties in BC patients.

Methods: Proliferation assays were carried out to demonstrate how ADSC conditioned media influenced BC cell lines MDA-MB-231, SKBR3, and T47D. The expression of six miRNAs (miR-21, miR-133, miR-222, miR-146, miR-221, …

An Evaluation Of The Enjoyment Levels Of Participants Of Lifelab, A Health Literacy Intervention For Socially Disadvantaged Adolescents., Lorna Burke, Dr. Hannah Goss, Craig Smith, Dr. Johann Issartel, Dr. Sarahjane Belton

SURE Journal: Science Undergraduate Research Experience Journal

Aim: LifeLab is co-designed by and for Junior Cycle students from social disadvantage in Ireland, with the hope to improve health literacy and subsequent health outcomes in this cohort. The aim of this study was to evaluate the enjoyment levels of students participating in the pilot of LifeLab, with a view to informing future development of the intervention.

Method: As part of the process evaluation of the pilot of LifeLab, a series of focus groups and purposively designed enjoyment scales were completed by 80 adolescents, from one disadvantaged school in Dublin, Ireland. Inductive thematic analysis was carried out to analyse …

The Acute Effects Of Talocrural Mwm Compared With The Application Of Soft-Tissue Of The Plantarfascia On Chronic Lateral Ankle Sprains For Ankle Dorsiflexion R.O.M., Peter Hempenstall, Brian O'Rourke

SURE Journal: Science Undergraduate Research Experience Journal

Previous research has looked at various treatment remedies for improving acute ankle Dorsiflexion Range of Motion (DFROM) post chronic Lateral Ankle Sprain (LAS). Mulligan’s Mobilisation with Movement (MWM) appears frequently however, the significance and mechanism remain quite conflicting (Gilbreath et al., 2015). It is also known that after a LAS, the Lateral Ligament Complex (LLC) is compromised and the calcaneus inverts, increasing stiffness of plantarfascia (Al-Mohrej & Al-Kenani, 2016, Denegar et al., 2002, Loudon & Bell, 1996). The objective of this study was to further explore the effectiveness of MWM compared with soft-tissue (ST) application of the plantarfascia on acute …

Therapies For Mitochondrial Disorders, Kayli Sousa Smyth, Anne Mulvihill

SURE Journal: Science Undergraduate Research Experience Journal

Mitochondria are cytoplasmic, double-membrane organelles that synthesise adenosine triphosphate (ATP). Mitochondria contain their own genome, mitochondrial DNA (mtDNA), which is maternally inherited from the oocyte. Mitochondrial proteins are encoded by either nuclear DNA (nDNA) or mtDNA, and both code for proteins forming the mitochondrial oxidative phosphorylation (OXPHOS) complexes of the respiratory chain. These complexes form a chain that allows the passage of electrons down the electron transport chain (ETC) through a proton motive force, creating ATP from adenosine diphosphate (ADP). This study aims to explore current and prospective therapies for mitochondrial disorders (MTDS). MTDS are clinical syndromes coupled with abnormalities …

Introduction To The Fourth Edition Of Eimi, Norman Friedman

Spring: The Journal of the E. E. Cummings Society

No abstract provided.

E.E. Cummings’ Fluid “Objectivity”: A Deep Ecological Response To Michael Webster’S “The New Nature Poetry And The Old”, Etienne Terblanche

Spring: The Journal of the E. E. Cummings Society

No abstract provided.

Two Reviews Of Christopher Sawyer-Lauçanno, E. E. Cummings: A Biography, Iain Landles, Michael Webster

Spring: The Journal of the E. E. Cummings Society

No abstract provided.

Three Poets, Gerald Locklin, Tricia Cherlin, Christopher Mulrooney

Spring: The Journal of the E. E. Cummings Society

No abstract provided.

Three Memorials, Michael Webster

Spring: The Journal of the E. E. Cummings Society

No abstract provided.

For The Record

Spring: The Journal of the E. E. Cummings Society

No abstract provided.

Review Of Friedman's (Re)Valuing Cummings And Martin Heusser's I Am My Writing, Michael P. Webster

Spring: The Journal of the E. E. Cummings Society

No abstract provided.

The Weight Of Tradition: Adynata And The "World Upside Down" In The Poetcy Of E. E. Cummings, Antonio Ruiz

Spring: The Journal of the E. E. Cummings Society

No abstract provided.

Interdependence Versus Transcendence, Norman Friedman

Spring: The Journal of the E. E. Cummings Society

No abstract provided.

E.E. Cummings- A Centennial Panel Discusssion

Spring: The Journal of the E. E. Cummings Society

No abstract provided.

Lessons Learned: Patrick Honohan, Maryann Haggerty

Journal of Financial Crises

Patrick Honohan, an economist, was governor of the Central Bank of Ireland and a member of the Governing Council of the European Central Bank (ECB) from September 2009 until November 2015. Early in his tenure, he led a team that investigated the causes of the Irish banking crisis that broke out in 2008 during the Global Financial Crisis. Resolving the problems of bank failure and over-indebtedness that emerged in that crisis dominated his term of office. In late 2010, Ireland had to request financial assistance from the “troika” of the International Monetary Fund (IMF), the European Commission, and the European …

Malaysia: Reserve Requirements, Afc, Bailey Decker

Journal of Financial Crises

Bank Negara Malaysia (BNM) unpegged the ringgit in July 1997, days after Thailand floated the baht. Ringgit depreciation and adverse investor sentiment worsened, contributing to a domestic liquidity shortage and capital flight. Malaysia experienced market instability in the early months of 1998, particularly pressure on its exchange rate, foreign currency reserves, and interest rates. At the same time, disruptions in the domestic money market and loan intermediation process caused an increase in lending rates, which resulted in debt servicing problems and weakened financial stability. To facilitate lending and productive economic activity, BNM twice lowered the statutory reserve requirement (SRR) at …

Jamaica: Reserve Requirements, Gfc, Corey N. Runkel

Journal of Financial Crises

In October 2008, the Global Financial Crisis (GFC) and liquidity shortages rocked American and European markets, causing investors to exit liquid Jamaican-dollar assets. The Bank of Jamaica (BOJ) feared a “disorderly depreciation” in the Jamaican-dollar (JMD) exchange rate to the US dollar (BOJ 2009, 44). In response, the BOJ raised required reserve ratios for cash and other liquid assets, the first increases since 2002. The BOJ raised reserve ratios three times—in December 2008, January 2009, and February 2009—because the central bank could not change its requirements by more than 200 basis points per month. The BOJ raised the requirement for …

India: Reserve Requirements, Gfc, Sharon Nunn, Carey K. Mott

Journal of Financial Crises

As international funding sources dried up during the Global Financial Crisis of 2007–2009 (GFC), businesses in India sought funds from domestic financial institutions, straining banks and lifting short-term lending rates. The liquidity pressure, coupled with sharp asset price corrections and rupee depreciation, restricted credit expansion in India. The Reserve Bank of India (RBI) responded with a suite of liquidity measures, including cuts to its two reserve requirement ratios, the cash reserve ratio (CRR) and the statutory liquidity ratio (SLR). The RBI cut the CRR over the course of four months from October 2008 to January 2009, lowering the ratio from …

Czech Republic: Reserve Requirements, 1997, Benjamin Hoffner

Journal of Financial Crises

In the first quarter of 1997, fiscal and current account deficits in the Czech Republic put pressure on the koruna’s pegged exchange rate as capital flowed out of the domestic economy. Although the Czech National Bank (CNB) committed to tight monetary policy to protect the peg, on April 11, the CNB announced a lowering of the minimum reserve requirement (RR) ratio from 11.5% to 9.5%, effective May 8. The RR ratio (RRR) reduction (RRR) reflected a compromise with the government, which had petitioned the central bank to ease monetary policy. To improve the balance of payments, the government also implemented …

Ecuador: Blanket Guarantee, 1998, Bailey Decker

Journal of Financial Crises

After a series of exogenous shocks hit the Ecuadorian economy in 1997–1998, foreign creditors reassessed their emerging-market risk and reduced external credit lines to Ecuador, thus draining liquidity. The closure of a small bank called Solbanco in April 1998 triggered deposit runs at other banks. Banks sought assistance from the Central Bank of Ecuador (Banco Central del Ecuador, or BCE). By the end of September 1998, the BCE had issued emergency loans to 11 financial institutions, totaling nearly 30% of the money base. The crisis accelerated in August 1998 when Banco de Prestamos, the sixth-largest bank, was closed; the existing …

Blanket Guarantees Survey, Christian M. Mcnamara, Carey K. Mott, Greg Feldberg, Andrew Metrick

Journal of Financial Crises

This paper surveys 10 blanket guarantee (BG) programs across 13 Key Design Decisions. The defining characteristics of these programs in terms of their inclusion in our BG series are (a) that they guaranteed a broader range of liabilities beyond deposit accounts and (b) that the guarantees covered existing liabilities in addition to newly issued ones. Each case represents an effort to eliminate creditors’ incentive to withdraw funding from institutions by guaranteeing that the funding will be paid back even if the institutions are unable to do so themselves. The main themes that emerge are: (a) the inability of blanket guarantees …

The Financialization Of Recession Response, Aaron Klein

Journal of Financial Crises

This paper analyzes economic policy responses to the COVID-19-induced recession, focusing on the American policy response. Despite widespread political distrust between the two parties sharing control of the government and the timing of the upcoming presidential election, America’s political system was able to enact a massive policy response that reduced the severity of the recession. This political response happened faster than any automatic policy response would have, based on the delays in data reporting. The economic policies enacted continued America’s trend toward financialization of fiscal policy. The Federal Reserve and America’s private banking and financial systems were heavily relied upon …

Wagon Tracks Volume 37, Issue 1 (November 2022)

Wagon Tracks

Contents

2 On the Cover: Starvation Peak by Dennis Maloney

4 Insights from your President

6 Joanne’s Jottings

5, 8-9 Trail News

10 The First Printing Press in New Mexico

11 Poetry: "Youth on the Santa Fe Trail," "Rendezvous 2022," by Ron Wilson

12 Ancestors on the Trail: Marion Sloan Russell and Claude Francis LaLoge

13-20 Poetry, Novels, Movies, and Children's Literature of theSanta Fe Trail by Dr. Michael Olsen

20 Letter to the Editor

21-30 A Trail Tale Revisited: The Death of Jedediah Smith on the Cimarron River in 1831 by Craig Crease

31 Chapter Reports

33 Membership Form …

One-Week Inquiry About Gravity Force With A Student Who Is Blind, Mustafa Şahin Bülbül Dr.

Journal of Science Education for Students with Disabilities

This study was conducted with a student who is visually impaired and questioned the force of gravity. The different stages encountered in the process were specified as steps in the study and it was shared what kind of inquiry form was needed at each step. There are different activities such as waiting for a week and thought experiment in the inquiry activity. The basis of the activity is that three balls of different mass left on a sponge leave different traces on the sponge.

Comparison Of Pregnancy Complication Rates: Does Opioid Agonist Pharmacotherapy Make A Difference?, Alexa Pfeiffer Oms-Iii, Michael Falcone Oms-Iii, Pritha Aggarwal Oms-Iii, Andrea M. Bodine Md

Advances in Clinical Medical Research and Healthcare Delivery

Background: Over the past decade, the prevalence of opioid use disorder (OUD) in pregnant patients has increased by 131% with an associated increase in pregnancy complications. Opioid agonist pharmacotherapy (OAP) with methadone or buprenorphine is recommended by ACOG for the management of OUD. The objectives of our study are to compare the incidence of pregnancy complications among patients who at the time of their delivery used OAP, OAP plus any additional substance (OAP+), illicit or prescribed opioids, and no opioids.

Methods: We conducted a retrospective cohort study at Berkshire Medical Center in Pittsfield, MA, between January 1, 2018, through December …

2022-12-21_Michiganoverview_Covidvaccinestats, Michigan Department Of Health & Human Services

Michigan COVID-19 Vaccine Data

The COVID Vaccine Dashboard page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/resources/covid-19-vaccine/covid-19-dashboard.

First-dose tracker above is for entire Michigan Population. Coverage maps below are for age 5+.

Previously reported numbers of administered vaccine doses may change as new data are received. A possible lag in reporting vaccine doses will result in increases in numbers previously reported.

This report is created by the Michigan Department of Health and Human Services Division of Immunization from data reported to the Michigan Care Improvement Registry (MCIR).

The dashboard contained the tabs Primary Series Doses Administered, Primary Series Doses by Vaccine, …

Laura Eaton V. Richard Figaski

2022 Decisions

USDC for the Western District of Pennsylvania

Self-Perceived Job Performance As A Mediator Of The Effects Of Academic Satisfaction And Quality On Loyalty, Lovemore Chikazhe, Charles Makanyeza

Journal of Marketing and Consumer Behaviour in Emerging Markets

Globally, there is increased customer mobility and competition within the higher education sector. As such, university management and administration practices should consider academic satisfaction, quality and loyalty as important factors to influence graduate job performance. The study was conducted to see if self-perceived job performance had a role in mediating the effect of academic satisfaction and perceived academic quality on academic loyalty. Data was collected from 714 respondents using a cross-sectional survey. The covariance-based structural equation modelling was used to test the hypotheses. According to the study results, self-perceived job performance partially mediates the eff ect of both academic satisfaction …

Stabilized Core Gene And Pathway Election Uncovers Pan-Cancer Shared Pathways And A Cancer-Specific Driver, Pathum Kossinna, Weijia Cai, Xuewen Lu, Carrie S Shemanko, Qingrun Zhang

Department of Cancer Biology Faculty Papers

Approaches systematically characterizing interactions via transcriptomic data usually follow two systems: (i) coexpression network analyses focusing on correlations between genes and (ii) linear regressions (usually regularized) to select multiple genes jointly. Both suffer from the problem of stability: A slight change of parameterization or dataset could lead to marked alterations of outcomes. Here, we propose Stabilized COre gene and Pathway Election (SCOPE), a tool integrating bootstrapped least absolute shrinkage and selection operator and coexpression analysis, leading to robust outcomes insensitive to variations in data. By applying SCOPE to six cancer expression datasets (BRCA, COAD, KIRC, LUAD, PRAD, and THCA) in …

Inequality Among The Disadvantaged? Racial/Ethnic Disparities In Earnings Among Young Men And Women Without A College Education, Byeongdon Oh, Daniel Mackin Freeman, Dara Shifrer

Sociology Faculty Publications and Presentations

Despite the rapid expansion of higher education, many young adults still enter the labor market without a college education. However, little research has focused on racial/ethnic earnings disadvantages faced by non-college-educated youth. We analyze the restricted-use data from the High School Longitudinal Study of 2009 to examine racial/ethnic earnings disparities among non-college-educated young men and women in their early 20s as of 2016, accounting for differences in premarket factors and occupation with an extensive set of controls. Results suggest striking earnings disadvantages for Black men relative to white, Latinx, and Asian men. Compared to white men, Latinx and Asian men …