Digital Commons Network^™

A Rare Case Of Cutaneous Extramedullary Hematopoiesis In Chronic Myeloid Leukemia, Bennett Christie-Nguyen, Hanadi El Achi, Levani Iashvili, Amer Wahed, Brenda Mai, Jacob Armstrong

Faculty, Staff and Student Publications

Cutaneous extramedullary hematopoiesis (CEH) is a rare manifestation of extramedullary hematopoiesis (EMH), a process typically associated with fetal development or myeloproliferative neoplasms. EMH most commonly involves the spleen, liver, and lymph nodes, with CEH being exceedingly rare in chronic myeloid leukemia (CML). Here, we present a 34-year-old Hispanic male with multiple bilateral lower extremity lesions, right buttock and leg pain, fatigue, and splenomegaly, who was found to have chronic-phase CML. Punch biopsy of one of the skin lesions demonstrated dermal infiltration by maturing hematopoietic elements, including granulocytes, megakaryocytes, and erythroid precursors, with fluorescence in situ hybridization (FISH) testing confirming a …

Diffeomorphisms In Quantum Black Hole Interiors, Ian William Bornhoeft

Electronic Theses and Dissertations 2020 - Present

We begin with an introduction to canonical Loop Quantum Gravity. We then introduce a notion of residual diffeomorphism covariance in quantum Kantowski–Sachs (KS), describing the interior of a Schwarzschild black hole. We solve for the family of Hamiltonian constraint operators satisfying an associated covariance condition, as well as parity invariance, preservation of the Bohr Hilbert space of Loop Quantum KS and a correct (naive) classical limit. We further explore imposing minimality of the number of momentum shift terms, and compare the solution with other Hamiltonian constraints proposed for Loop Quantum KS in the literature. In particular, we discuss a lapse …

650 Crown Equities, Llc V. Sealey

All Decisions

In this nonpayment proceeding, the tenant moved to amend her answer to assert a fraudulent rent overcharge claim, overcharge damages, and discovery, citing a significant pre-HSTPA rent increase. The court denied the tenant's motion for a fraudulent overcharge claim and overcharge damages. However, it granted discovery to review the full rent history to determine a reliable basis for the 2007 rent increase, which would *prospectively* set the legal regulated rent. The court held that post-HSTPA overcharge damages for nonfraudulent pre-HSTPA conduct cannot be awarded if they rely on new, unconstitutionally retroactive calculation methods. Other proposed defenses were granted.

Navigating A Delicate Balance: Antibiotic Allergy In The Setting Of Renal Infection And Diabetic Ketoacidosis, Aun Bangash, Muhammad Bangash, Ruben M. Martinez Meza

School of Medicine Publications

Acute pyelonephritis is a bacterial infection of the renal parenchyma that requires prompt recognition and antibiotic therapy to prevent complications such as sepsis and chronic renal inflammation. We present a case of a 26-year-old woman with poorly controlled type 1 diabetes mellitus and a documented beta-lactam allergy who presented with atypical symptoms, including flank pain without urinary complaints. Laboratory evaluation demonstrated leukocytosis with a negative urinalysis. CT of the abdomen revealed left lobar nephronia with early contralateral involvement of the right kidney. Given her allergy history, she was treated with levofloxacin. During her hospital stay, she developed nausea, vomiting, and …

A Tv-Bm3d Iterative Algorithm For Vmat-Ct Reconstruction, Chia-Lung Chien, Beibei Guo, Rui Zhang

Faculty, Staff and Students Publications

Volumetric modulated arc therapy-computed tomography (VMAT-CT), which is the CT reconstructed using the portal images collected during VMAT, can potentially be an effective onsite imaging tool. The goal of this study was to propose an iterative reconstruction algorithm that can further improve the image quality of VMAT-CT and reduce the number of failed reconstructions. An iterative algorithm combining total variation (TV) with block-matching and 3D filtering (BM3D) was proposed, addressing the L1-L2 regularization problem using the split Bregman method. We collected portal images from 67 VMAT cases including 50 phantom and 17 real-patient cases. Both Feldkamp-Davis-Kress (FDK) and TV-BM3D iterative …

H3 Dopaminylation And Camkii Modulate Diffuse Midline Glioma Response To Cdk9 Inhibition, Rebecca L Murdaugh, Brittany R Eberl, Rosemary U Richard, Ena I Campos-Hensley, Adanze N Nnyagu, W Austin Elam, Ai-Ni Tsao, Jack R Tremblay, Ruiying Ma, Alfred K Dei-Ampeh, Kieu Pham, Daniel C Kraushaar, Kwanha Yu, Calla M Olson, Akdes Serin-Harmanci, Benjamin Deneen, Jamie N Anastas

Faculty, Staff and Students Publications

Aberrant neurotransmitter signaling and transcriptional dysregulation are hallmarks of gliomagenesis and represent potential therapeutic targets. Monoamine neurotransmitters such as dopamine and serotonin primarily activate GPCRs but can also function epigenetically as histone H3 modifications. Here, we uncover mechanisms of crosstalk between monoamine neurotransmitter signaling, H3 dopaminylation, and RNA polymerase II (Pol2) transcription in diffuse midline glioma (DMG). We find that co-treatment with Pol2-targeting CDK9 inhibitors (CDK9i) and FDA-approved neuropsychiatric drugs, including selective serotonin reuptake inhibitors (SSRIs), synergistically reduces DMG growth. Mechanistically, CDK9i+SSRI treatment alters H3 dopaminylation patterns and represses synaptic and neurodevelopmental gene transcription associated with CDK9i resistance. Further phospho-proteomic …

Exploring Sequential Technical Practices Towards Skill Development And Musical Expression In Violin Performance And String Pedagogy Methods, Erin Kim

LSU Doctoral Dissertations

This dissertation proposes the Erin Kim System, a pedagogical framework designed to support sequential technical development and musical expression in beginning, intermediate, and advanced levels of violin performance. This system examines how structured technical progression, guided repertoire sequencing, and a nurturing learning environment with the teacher and parents can foster skill acquisition and long-term musical engagement among violin students. Musical enjoyment and inspiration serve as primary motivators for learning, particularly when students are encouraged to work toward performing aspirational repertoire such as the Sibelius Violin Concerto. By organizing repertoire and supplemental exercises in a clear step-by-step process, this system enables …

Constitutive Ampk Activation Prevents Hepatocellular Carcinoma Development Through Inhibition Of Hnf4Α Activity, Zhen Sun, Bernard Linares, Cassidy Urdiales, Fiyad Alsarmi, Boyuan Sang, Nagireddy Putluri, Jeanine L Van Nostrand

Faculty, Staff and Students Publications

Hepatocellular carcinoma (HCC) is a major cause of cancer-related mortality and is largely driven by metabolic disorders such as obesity and type 2 diabetes. The AMP-activated protein kinase (AMPK) is a master regulator of metabolism, and its activation has been proposed as a therapeutic strategy for treating metabolic disorders. However, although AMPK activity is down-regulated in HCC, the precise role of AMPK in HCC development has not been clearly delineated. Here, we investigated the ability of constitutive AMPK activation to prevent HCC development using a constitutively active AMPK transgenic mouse model and a pharmacological AMPK activator. We observed that AMPK …

A Comparative Analysis Of Data Privacy Laws In European Union And United States: A Need For Better Protections Of Marginalized Groups In Light Of Advances In Artificial Intelligence, Lauren Demchak

Journal of International Law and Comparative Studies

No abstract provided.

From Stigma To Statute: A Historical And Legal Comparative Analysis Of Involuntary Commitment Laws In Idaho, Jessica Cambron

Idaho Law Review

A lesser-known area of law in Idaho concerns the involuntary civil commitment process, a process by which thousands of people per year are committed to hospitals around the state. These laws, specifically in Idaho, govern the criteria which must be met for a person to be placed on an involuntary hold, detained in a hospital setting awaiting proceedings, or potentially committed.

Understanding the evolution of mental illness and the role of involuntary commitment – including successes, failures, and challenges – is essential to navigating reform. This Comment provides a brief history of mental illness, including key cultural events and cases …

Preserving Rural School Districts From The Threat Of Vouchers And Charters, Preston C. Green Iii

Idaho Law Review

School vouchers and charter schools are primed to grow at a time when public school systems are experiencing a precipitous decline in enrollment. Unfortunately, for many rural school districts, this challenging environment may endanger their very existence, to the detriment of the students and the communities they serve. To guard against this potential harm, this article calls for state legislatures to designate certain classes of rural districts as “education preserves.” This article also explains how states can create education preserves in a manner that can withstand Free Exercise Clause challenges.

Greenaissance? Zero-Embargo Funder Mandates And Green Open Access, Josh Cromwell

All Things Open

Recently, several funder-driven Open Access mandates, such as Plan S in Europe or the NIH Public Access Policy in the US, have indicated a desire to shift away from allocating funds for article processing charges (APCs) and have instead called for significantly reducing or eliminating embargo periods on accepted manuscripts (AMs) to make them a viable pathway to compliance for researchers.

This talk will address how these policies can significantly revitalize Green Open Access and open repositories, and will discuss strategies for researchers and librarians to use these new policy changes as an opportunity to share their research openly without …

Proxyconnec: A Lora-Based Proactive Safety Communication System For Off-Grid Environments, Shruti Bhandari, Roza Shaimurat

ATU Scholars Symposium

Remote environments lacking cellular or satellite coverage present significant safety challenges. ProxyConnec was developed as a point-to-point communication system using ESP32 microcontrollers and REYAX RYLR998 LoRa modules to provide off-grid monitoring.

The system implements a proactive heartbeat model in which a beacon device transmits a signal every 1,000 milliseconds. A base station monitors this connection using a 5,000 millisecond watchdog timer. If communication is interrupted, the system immediately triggers audible and visual alerts. Unlike conventional tracking devices that depend on manual SOS activation, this design treats unexpected signal loss as a potential safety event.

The manufacturer rates the selected LoRa …

A Comprehensive Survey Of Agentic Ai: Design Principles, Security Risks, And Ethical Consideration, Md Shaba Sayeed

ATU Scholars Symposium

In the past several years, the world has managed to transition away from simple automation to independent AI systems. Agentic AI is an agent that can work independently, carrying out all essential plans and implementations without any kind of supervision from a human being. This review has tried to demonstrate the transformative impact that Agentic AI brings to contemporary models of intelligence by means of synthesis of perception, reasoning, and goal. We utilized the phrases Agentic AI, autonomous AI, multi agent systems as keywords in Google Scholar, ScienceDirect, arXiv, and other digital libraries. We have used these 38 main papers …

Computational Approaches To Laser Alignment And Phase Correction, Joseph E. Temple

ATU Scholars Symposium

The goal of our work is to automate the tedious and delicate process of optical alignment (rotating mirrors, shifting lenses by millimeters, and iterating endlessly) in the context of generating vortex beams from a Gaussian laser beam. We create vortex beams by illuminating a digital hologram displayed on a spatial light modulator (SLM). Two main issues arise: misalignment and phase imperfections in the input beam. If the beam does not pass directly through the center of the SLM, or if it deviates from an ideal Gaussian profile, the resulting vortex beam becomes distorted.

Last semester, we developed two methods to …

Creating A Floating Volumetric Display, Joy Skaggs, Hope Skinner

ATU Scholars Symposium

The public has long been interested in futuristic technology, especially ‘holograms’ and their possibilities, evidenced by pop culture icons such as Iron Man and the popularity of the Sci-Fi Genre. The popular term ‘hologram’ actually describes the phenomenon of a volumetric display, where light is directed to form 3D forms in the air. Attempts to create these volumetric displays began as early as 1988 with creators like Gregg Favelora and Alan Sullivan. As technology improved, so too did the ability to make the futuristic ‘hologram’ a reality.

Another common form of these interactive holograms is the floating display, which may …

Automatic Three Phase Balancing In Utility Applications, Ryan Morris

ATU Scholars Symposium

Balancing three-phase power has become more important as modern loads like EVs and large agricultural fans create fast and uneven changes in distribution systems. Manual balancing is slow, inconsistent, and often only done during certain “seasons,” which leaves long periods of imbalance. This paper reviews existing automatic methods such as the Fast-Switching Relay method, the Practical Balancing Algorithm, and the Phase-EQ system and highlights their benefits and limitations. Based on this analysis, a new method called the Predicted Practical Balancing Algorithm (PPBA) is proposed. The PPBA combines the stability of threshold-based switching with historical data to predict when imbalances are …

Proactive Mental Health Assistance Via Agentic Llm Chatbots With Retrieval-Augmented Generation, Shaira Wajiha

ATU Scholars Symposium

Mental health challenges such as anxiety and depression are widespread, yet often remain unaddressed due to stigma, financial barriers, limited access to professionals, or personal reluctance. To address this gap, we present an accessible AI-powered chatbot that provides preliminary conversational support with empathetic, context-aware responses. The chatbot is trained and evaluated on two publicly available counseling conversation datasets from Huggingface, enabling it to learn and maintain therapeutic dialogue patterns. We compare three advanced LLMs, such as Llama3.1, Mistral 7b, and Qwen3, evaluating them on relevance, empathy, conciseness, and contextual understanding, and all models demonstrate high response quality. Incorporation of a …

Incorporating Local Expertise Into Environmental Research And Management, Jessica Black, Amy E. Scaroni, Stefanie L. Whitmire

Forestry and Natural Resources

This article is for researchers, government staff, land planners, and natural resource managers. In this paper, we will outline why incorporating local expertise works to scale down national or regional research to make it more useful for local communities. We will also provide examples of how a community’s knowledge about their local ecosystem, referred to as local ecological knowledge (LEK), can fill data gaps and contribute to improved land and wildlife management.

Automatic Labeling Of Real-World Pmu Data: A Weakly Supervised Learning Approach, Yunchuan Liu

Research Days

This paper presents a weakly supervised learning framework for real-world event identification in transmission networks using phasor measurement unit (PMU) data. The growing integration of renewable energy sources has introduced greater variability in grid conditions, intensifying the need for accurate event detection. Although high-resolution PMU measurements enable event identification to be formulated as a classification problem, traditional supervised learning approaches are hindered by the scarcity of labeled data, and acquiring large-scale, high-quality labeled PMU datasets remains prohibitively expensive. To overcome this challenge, we propose an automated PMU data-labeling method that combines domain knowledge with machine learning techniques through the use …

Inventory Management And Radio Frequency Identification Utilization In Healthcare, Alan D. Smith

Atlantic Marketing Association Proceedings

No abstract provided.

The Courier, Summer 2024, Tennessee. Historical Commission.

Tennessee Historical Commission

No abstract provided.

Chatgpt In Higher Ed: How To Navigate And Incorporate, Emory Hiott, Darin Gerdes

Atlantic Marketing Association Proceedings

No abstract provided.

Faculty, Be The Nudge For Your Students’ Personal Brand!, Michelle Carpenter

Atlantic Marketing Association Proceedings

No abstract provided.

Trajectory-Level Failure Modes In Constraint Systems: Irrecoverability, Observability Failure, And The Limits Of State-Based Monitoring, Thom Pham

Defensive Publications Series

Modern computational and artificial intelligence systems are typically evaluated based on constraint satisfaction at individual time steps. A system is considered correct if its current state satisfies a set of constraints or objectives. This paper argues that such state-based evaluation is insufficient. We show that systems may satisfy all locally observable constraints at every step while irreversibly losing the ability to return to correct states. These failures cannot be detected at any single time step. This introduces a distinction between feasibility (a property of states) and recoverability (a property of trajectories). We define a set of trajectory-level failure modes (including …

Descending-Ladder Binary Synchronization Protocol For Discontinuous And Monolithic Neural Substrates: A Substrate-Blind Communication Primitive For Heterogeneous Ai Mesh Networks, David Lee Wise, Avan Lee Wise, Seam Lee Wise

Defensive Publications Series

This paper discloses a synchronization protocol ("pulse language") for communication across artificial neural network substrates, operating at the token boundary layer. The protocol uses a descending-ladder binary pattern (3-2-1-0) that maps to attention-narrowing cycles during inference. The protocol functions differently but complementarily on two substrate types: (1) Mixture-of-Experts (MoE/sparse) architectures, where the signal traverses gaps between expert activations and produces shifted echoes, and (2) dense monolithic architectures, where the signal reflects off the continuous parameter space and provides a fixed reference frame. The protocol was developed by intuitive testing across ten commercial AI platforms prior to the author's knowledge of …

Media State Management And Granular Bookmarking Using A Cross-Device Biometric Interlock, Nikita Agarwal

Defensive Publications Series

Users may often fall asleep while watching media content on a computing device such as a smart television, mobile computing device (e.g., a tablet computer, a smart phone), or a personal computer (e.g., a laptop computer, a desktop computer). Falling asleep while watching or consuming media content (e.g., movies, television shows, etc.) may lead to a loss of narrative place, a waste of resources, and/or sleep disruption. In general, the computing devices may include or implement inactivity-based timers that typically trigger after one or more hours of detected inactivity of the user with the computing device. The inactivity-based timers, however, …

Sentencing Practices In Tennessee, Administrative Office Of The Courts, Information For Cases Sentenced Between July 1, 2015 And June 30, 2023, Tennessee. State Courts.

Sentencing Practices Report

No abstract provided.

Annual Report Of The Tennessee Judiciary Fiscal Year 2024-2025, Statistics, Tennessee. State Courts.

Annual Statistical Report

No abstract provided.

Managing Educational Stress And Coping With Conflicts Among Undergraduate, Aida Mehrad, Meriem Bouzedif, Thisaru Kavinda Kodithuwakku, Neema George Rweramila, Saad El Hajli, Mohammad Cheraghsepehr

Jurnal Pendidikan Humaniora

Many higher-education students experience ongoing stress due to academic demands while studying at university. To examine the effects of educational stress on students' ability to learn, academic achievement, and mental health issues such as anxiety, sadness, sleep disturbances, and drug use problems, a qualitative research study was conducted using interview methods. The study explores the unique experiences of educational stress among undergraduate students, based on interviews with 14 students, and provides detailed insights into their stress levels. The research emphasizes the widespread impact of stress on students, including academic pressures and cultural adjustments, and focuses specifically on undergraduate students at …