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Interferon-Gamma Receptor Signaling Regulates Innate Immunity During Staphylococcus Aureus Craniotomy Infection, Zachary Van Roy, Gunjan Kak, Rachel W. Fallet, Tammy Kielian Jan 2025

Interferon-Gamma Receptor Signaling Regulates Innate Immunity During Staphylococcus Aureus Craniotomy Infection, Zachary Van Roy, Gunjan Kak, Rachel W. Fallet, Tammy Kielian

Journal Articles: Pathology and Microbiology

A craniotomy is a neurosurgical procedure performed to access the intracranial space. In 3-5% of cases, infections can develop, most caused by Staphylococcus aureus biofilm formation on the skull surface. Medical management of this infection is difficult, as biofilm properties confer immune and antimicrobial recalcitrance to the infection and necessitate additional surgical procedures. Furthermore, treatment failure rates can be appreciably high. These factors, compounded with rapidly expanding rates of antimicrobial resistance, highlight the need to develop alternative treatment strategies to target and reverse the immune dysfunction that occurs during biofilm infection. Our recent work has identified CD4+ Th1 and Th17 …


High-Grade Avm. Educational Vignette And Clinical Cases, Marcos Devanir Silva Da Costa, Marcelo Augusto Acosta Goiri, Daniela Coelho, Juan Alberto Paz Archila, Talita Helena Martins Sarti, Feres Chaddad-Neto Jan 2025

High-Grade Avm. Educational Vignette And Clinical Cases, Marcos Devanir Silva Da Costa, Marcelo Augusto Acosta Goiri, Daniela Coelho, Juan Alberto Paz Archila, Talita Helena Martins Sarti, Feres Chaddad-Neto

Archives of Neurosurgery

The arteriovenous malformation (AVM) is a vascular malformation characterized by fistulas between arteries and veins forming a nidus, without interposition of capillary vessels and of which early draining vein is identified at the digital angiography. Potential reports of its existence date from the second century AD. Spetzler and Martin (S-M) proposed a classification considering three features and Lawton then added new predictors. A maximum of 10 score can be achieved by applying the modified S-M grade system. This classification guides decision-making and the possible choice of the multimodal treatment (surgery, radiosurgery and embolization). We discuss historical, pathological, clinical and therapeutic …


Monroe, New Hampshire Annual Report Of The Monroe Town Officers For The Year Ending December 31, 2024, Monroe Town Representatives Jan 2025

Monroe, New Hampshire Annual Report Of The Monroe Town Officers For The Year Ending December 31, 2024, Monroe Town Representatives

Monroe, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.


Examining The Relationship Between Teen Pregnancy And Educational Outcomes In Ohio, Andrea Szep, Maryyam Durrani Jan 2025

Examining The Relationship Between Teen Pregnancy And Educational Outcomes In Ohio, Andrea Szep, Maryyam Durrani

Scholarship in Medicine - All Papers

Objective: The aim of this study is to explore the relationship between educational outcomes,school funding, and teen birth rates in Ohio counties between 2020 and 2024. Methods: Usingdata from County Health Rankings, we performed regression, correlation, and paired t-testanalyses through the SPSS software. Results: The results of our tests showed significantnegative correlations between markers of educational success, including high school graduationrates math and reading standardized test scores, and teen birth rates in both 2020 and 2024.Between 2020 and 2024, the teen birth rate decreased in the state of Ohio, and in 2024, publicschool funding was able to predict 14.8% of …


Building Partnerships To Address Food Insecurity, Diane M. Taylor Jan 2025

Building Partnerships To Address Food Insecurity, Diane M. Taylor

Community Engagement Student Work

Presently in Massachusetts, one in three adults experience food insecurity. The problem is exacerbated by the high cost of living in the state, and its disproportionate effect on minority populations. To address these issues, this research has three major goals: 1) to educate community members working in the food insecurity field by providing a foundational understanding of the topic, 2) to provide the opportunity for stakeholders to network and meet others working in the field of food security, and 3) to share effective strategies for building strong, successful, sustainable partnerships and collaborations, which will create greater impact. For the purpose …


Lifting As We Climb: Mentorship As A Catalyst For Retention Among Black Male College Students, Dejour Hollins Jan 2025

Lifting As We Climb: Mentorship As A Catalyst For Retention Among Black Male College Students, Dejour Hollins

Community Engagement Student Work

The retention rates of Black male students in U.S. higher education institutions are critically low. This capstone identifies the variety of barriers that Black males face that contribute to these low college retention rates and explores the role of mentorship as a catalyst for improving retention rates among Black male college students. By utilizing Bronfenbrenner’s Ecological Systems Theory as a framework, this research highlights how various environmental influences interact to impact student retention. The project includes a community workshop aimed at fostering a deeper understanding of how mentorship can support Black male students in their academic, emotional and personal journeys. …


Parnassus 2025: Hephaestic Voices Jan 2025

Parnassus 2025: Hephaestic Voices

Parnassus

No abstract provided.


Debating Member-Checks Of Exceptional Human Experiences, James Houran, Everton De Oliveira Maraldi, Beth M. Houran Jan 2025

Debating Member-Checks Of Exceptional Human Experiences, James Houran, Everton De Oliveira Maraldi, Beth M. Houran

International Journal of Transpersonal Studies Advance Publication Archive

This integrative essay reflects on member-checking and engaged research approaches in the study of exceptional human experiences (EHEs)—subjective accounts that often challenge conventional views of consciousness and physical reality. Member-checking, or inviting research participants to review data or interpretations, can improve credibility by aligning research with their lived experience. While benefits include transparency and insight, risks include confirmatory bias, emotional distress, power asymmetries, and logistical complexity. The evolving nature of EHEs further complicates participant validation. We therefore advocate a six-level "fit-for-purpose" system to balance rigor with ethical care and responsiveness. We also explore digital, asynchronous, and AI-assisted strategies to enhance …


2025 Volunteer Impact Report, Tennessee. Department Of Disability And Aging Jan 2025

2025 Volunteer Impact Report, Tennessee. Department Of Disability And Aging

Volunteer Impact Report

This report highlights the accomplishments and statistics concerning volunteer programs for the department.


Town Of Merrimack, Nh Annual Report 2024, Merrimack Town Representatives Jan 2025

Town Of Merrimack, Nh Annual Report 2024, Merrimack Town Representatives

Merrimack, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.


Pase: Professionalism And Surgical Ethics. A Comprehensive Curriculum For General Surgery Residents, Baila Maqbool Jan 2025

Pase: Professionalism And Surgical Ethics. A Comprehensive Curriculum For General Surgery Residents, Baila Maqbool

Surgical Education

The PASE curriculum addresses the gap in ethics education for surgery residents by integrating formal instruction with practical application through diverse instructional methods. It ensures that residents are well-prepared for the ethical challenges in modern surgical practice. Future directions include expanding the curriculum to include advanced topics, interdisciplinary team simulations, and feedback from patient advocates to further enhance the ethical development of residents.


Mental Health Stigma As A Barrier To Care, Whitney Grant Jan 2025

Mental Health Stigma As A Barrier To Care, Whitney Grant

Regis University Student Publications (comprehensive collection)

Abstract

Mental health stigma is a major barrier to care. The mental health stigma as a problem is relevant due to its influence on increasing the burden of mental health issues due to a lack of help-seeking, contributing to increased healthcare costs, and increasing adverse health outcomes. Currently there is no action consistently taken to assess or address this stigma in the primary care setting. Healthcare professionals can help to reduce the perceptions of stigma and lessen stigma as a barrier to care. A quality improvement project was implemented to evaluate if an education intervention by a primary care provider …


Annual Report For The Town Of Andover, New Hampshire, Fiscal Year Ending December 31, 2024, Andover Town Representatives Jan 2025

Annual Report For The Town Of Andover, New Hampshire, Fiscal Year Ending December 31, 2024, Andover Town Representatives

Andover, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.


2025 Inscape, Morehead State University. Jan 2025

2025 Inscape, Morehead State University.

Inscape: Art & Literary Magazine Archive

The 2025 edition of the Inscape: Literary and Art Magazine.


2024 Annual Report Barrington, New Hampshire, Barrington Town Representatives Jan 2025

2024 Annual Report Barrington, New Hampshire, Barrington Town Representatives

Barrington, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.


Town Of Colebrook Annual Report Year Ending December 31, 2024, Colebrook Town Representatives Jan 2025

Town Of Colebrook Annual Report Year Ending December 31, 2024, Colebrook Town Representatives

Colebrook, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.


The 386th Annual Report Town Of Hampton, New Hampshire Calendar Year Ending December 31, 2024, Hampton Town Representatives Jan 2025

The 386th Annual Report Town Of Hampton, New Hampshire Calendar Year Ending December 31, 2024, Hampton Town Representatives

Hampton, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.


Town Of Gilsum, New Hampshire Annual Reports For The Year Ending December 31, 2024, Gilsum Town Representatives Jan 2025

Town Of Gilsum, New Hampshire Annual Reports For The Year Ending December 31, 2024, Gilsum Town Representatives

Gilsum, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.


Reproductive Autonomy In Immunological Intervention: Ethical Boundaries In Maternal-Fetal Immune Therapy, Marium Z. Rizvi Jan 2025

Reproductive Autonomy In Immunological Intervention: Ethical Boundaries In Maternal-Fetal Immune Therapy, Marium Z. Rizvi

Journal of Health Ethics

Recent advances in immunology have broken barriers in reproductive medicine through immune-modulating therapies that support fertility and pregnancy. Treatments such as intravenous immunoglobulin (IVIG) and intralipid infusions are increasingly offered to patients with Recurrent Implantation Failure (RIF) or Recurrent Pregnancy Loss (RPL), conditions that result in miscarriages and failed IVF treatments (Pillarysetti et al., 2023). Maternal-fetal immunology reveals a delicate interplay between immune tolerance and defense: the maternal system must accept a genetically foreign fetus while preserving immunological protection. Disruptions in this balance are implicated in implantation disorders and pregnancy failure. As a result, immune-based therapies have emerged as promising …


Perceptions Of Fidelity, Urgency, And Challenges In Dei Implementation: Insights From Long Island Teacher Union Presidents, Shirley M. Pincay Jan 2025

Perceptions Of Fidelity, Urgency, And Challenges In Dei Implementation: Insights From Long Island Teacher Union Presidents, Shirley M. Pincay

Selected Full Text Dissertations, 2011-

This study examines the fidelity, urgency, and challenges of implementing the Culturally Responsive-Sustaining Education (CR-SE) Diversity, Equity, and Inclusion (DEI) Framework as the NYSED DEI policy in Long Island public school districts. The New York State Board of Regents developed the CR-SE and DEI Framework to promote inclusivity and cultural awareness in educational settings, encouraging districts to adopt practices that affirm and support students from diverse backgrounds. Using a qualitative approach, incorporating a survey and a virtual semi-structured interview, data was collected from Teacher Union Presidents across various Long Island school districts. Key variables included levels of urgency and fidelity …


Policy Considerations Of Open-Source Intelligence: A Study Of Bellingcat's Online Investigation Patterns (2014-2024), Lora Pitman, Logan Walsh Jan 2025

Policy Considerations Of Open-Source Intelligence: A Study Of Bellingcat's Online Investigation Patterns (2014-2024), Lora Pitman, Logan Walsh

International Journal of Cybersecurity Intelligence & Cybercrime

With the proliferation of social media and digital information tools, more and more internet users can participate in intelligence collection through open-source investigations – an area previously reserved for government agencies with access to classified information. The availability and easy access to open-source information, however, has raised some policy and ethical issues over time. Arguments were expressed in the literature, according to which, some of the most popular open-source investigation platforms collect and use information sometimes at the expense of the safety of users who posted the information online, unaware of how it was going to be utilized. Therefore, this …


Teaching And Learning International Survey (Talis) 2024 Conceptual Framework, John Ainley, Wolfram Schulz Jan 2025

Teaching And Learning International Survey (Talis) 2024 Conceptual Framework, John Ainley, Wolfram Schulz

OECD Teaching and Learning International Survey (TALIS)

This document articulates a conceptual framework for the fourth cycle of the Teaching and Learning International Survey (TALIS) programme, TALIS 2024. It reflects major concepts from research literature as well as policy interests and was developed by researchers in consultation with the OECD, international stakeholders, and participating countries and territories. The 2024 cycle is designed to address four contemporary issues for education systems and four broad content areas concerned with teaching and learning. The contemporary issues for education systems are: diversity and equity; the educational use of technology; social and emotional learning; and environmental and sustainability education. The broad content …


Southern Adventist University Undergraduate Handbook 2024-2025, Southern Adventist University Jan 2025

Southern Adventist University Undergraduate Handbook 2024-2025, Southern Adventist University

Student Handbooks, Undergraduate

No abstract provided.


Queerness Through The Lens Of Abjection, Games, And Ai, Ryan Nguyen Jan 2025

Queerness Through The Lens Of Abjection, Games, And Ai, Ryan Nguyen

HMC Senior Theses

I have always understood queerness in relation to the heteronormative standards that our modern society imposes. That is, despite being queer, my own perception of my identity has been that it is abject. The abject is what disturbs identity, system, order, and what does not respect borders, positions, and rules. I have been indoctrinated to believe that queerness is a disturbance to the current system, that it is unnatural and repulsive. However, there is value in abjection. When faced with a primal repulsion, the boundaries between the Self and the Other are confronted and begin to break down. By breaking …


Leadership’S Influence Over Turnover, Skill Retention And Building, And Company Culture, Joseph R. Stevenson Jan 2025

Leadership’S Influence Over Turnover, Skill Retention And Building, And Company Culture, Joseph R. Stevenson

M.S. in Leadership

This capstone project explores the role of leadership in employee retention and turnover within the manufacturing industry. The project was chosen due to ongoing workforce challenges, including high turnover rates, skill shortages, and the increasing impact of automation and digital transformation. The study uses a mixed-methods approach, combining qualitative analysis of academic literature, case studies, and company policies with quantitative data from labor statistics and industry reports. The research identifies key factors influencing retention, including leadership style, compensation, workplace culture, and career development opportunities. Findings show that transformational leadership, clear advancement pathways, and a supportive workplace culture significantly improve employee …


Litigating Landlessness: The U.S. Department Of The Interior And First Circuit Court’S Appropriations Of Self-Governance And Socialism In Puerto Rico, 1934-52, Carmen Lopez Villamil Jan 2025

Litigating Landlessness: The U.S. Department Of The Interior And First Circuit Court’S Appropriations Of Self-Governance And Socialism In Puerto Rico, 1934-52, Carmen Lopez Villamil

Kaplan Senior Essay Prize for Use of Library Special Collections

In 1946, three Boston judges decided that the Puerto Rican legislature could redistribute American-owned sugar plantations to workers. Though deemed legal, the redistribution never happened. The unreported 1946 land rights case, People of Puerto Rico v. Eastern Sugar Associates, entangles how self-proclaimed socialist and anti-colonialist officials at the Department of the Interior administered a New Deal empire across Indigenous and island territories. In conjunction with the Department of the Interior’s published reports and Felix S. Cohen’s Papers at the Yale Beinecke Rare Book and Manuscript Library, case files from the Boston First Circuit Library reveal engagement between federal and military …


The Effect Of Two Common Herbicides On The Growth And Development Of Two Anuran Species (Boreorana Sylvatica And Dryophytes Chrysoscelis), Jerica Eaton Jan 2025

The Effect Of Two Common Herbicides On The Growth And Development Of Two Anuran Species (Boreorana Sylvatica And Dryophytes Chrysoscelis), Jerica Eaton

Masters Theses & Specialist Projects

Amphibian populations have been declining globally since the 1950s. Many species that have experienced declines are viewed as 'environmental indicators' that reveal habitat degradation. Declines can be attributed to several factors, including chemicals used in agriculture, such as Roundup and Atrazine. Agrochemicals contaminate water bodies through runoff or leaching and cause alterations to aquatic ecosystems. This study evaluated the effects of herbicide usage on two wild anuran populations using wood frogs (Boreorana sylvatica) and Cope’s gray tree frogs (Dryophytes chrysoscelis) as a model. We determined the effect of the herbicides at two concentrations, a high concentration …


Balancing Sustainability With Preservation In Historic Italian Architecture, Maya A. Bruno Jan 2025

Balancing Sustainability With Preservation In Historic Italian Architecture, Maya A. Bruno

CISLA Senior Integrative Projects

This research examines the intersection of historic preservation and sustainability in Italian architecture, analyzing how architects and contractors adapt historic structures to modern energy efficiency standards while maintaining cultural integrity. Using three Italian case studies—Ex-STA.VE.CO in Bologna, Sant’Apollinare in Perugia, and Castelvecchio in Verona—the study explores common challenges in regulatory compliance, material constraints, energy efficiency, seismic resilience, and adaptive reuse. Each case illustrates how sustainability measures interact with Italy’s stringent conservation laws and how historic buildings, inherently designed for climate adaptability, can be innovatively retrofitted. The findings provide insights into reconciling preservation principles with sustainable interventions, offering policy recommendations for …


Factors Impacting Undergraduate Student Use Of Mental Health Care In The U.S. And France, Samantha Lamontagne Jan 2025

Factors Impacting Undergraduate Student Use Of Mental Health Care In The U.S. And France, Samantha Lamontagne

CISLA Senior Integrative Projects

No abstract provided.


Interactions Policières Et Expériences Des Femmes Et Des Enfants Réfugiés Dans Le Nord De La France, Nora May Pulsifer Jan 2025

Interactions Policières Et Expériences Des Femmes Et Des Enfants Réfugiés Dans Le Nord De La France, Nora May Pulsifer

CISLA Senior Integrative Projects

No abstract provided.