Digital Commons Network^™

Conference Planning Committee Update, Amy Carlson, Karen Spence, Sonali Sugrim

NASIG Newsletter

No abstract provided.

Nasig Board Conference Call March 3, 2025

NASIG Newsletter

No abstract provided.

Committee Annual Reports And Updates

NASIG Newsletter

No abstract provided.

May 2025 Full Issue, Faye M. O'Reilly

NASIG Newsletter

No abstract provided.

April 4, 2025 Board Meeting Minutes

NASIG Newsletter

No abstract provided.

May 12, 2025 Board Meeting Minutes

NASIG Newsletter

No abstract provided.

Proactive Approach To Identify And Mitigate Cybersecurity Threats In Smart Building Using Ai, Shayma Abdulla Alhayyas

Theses

Smart buildings form a cornerstone of modern urban development. The integration of Internet of Things (IoT) devices in buildings has revolutionized facility management, improving system intelligence and user experience. However, these smart devices also introduce cybersecurity challenges and risks. The initiative "Identifying and Mitigating Cybersecurity Threats in Smart Building using AI" focuses on leveraging advanced artificial intelligence (AI) to address and mitigate cybersecurity threats within smart buildings. This study integrates predictive analytics, deep learning, and machine learning to identify and prevent cyberattacks, protecting sensitive data and networked IoT devices. By analyzing previous attack patterns, network behaviors, and potential vulnerabilities, this …

Enhancing Third-Party Risk Management In Aviation: A Comprehensive Framework For Modern Challenges, Shamma Hussain Hammad Bin Hammad

Theses

This thesis is focused on improving the way airlines have managed risks from third-party vendors. Emirates and Etihad have been used as case studies. The thesis identifies major issues, including cybersecurity threats, slow manual processes, and the challenges in the following global regulations. To To solve such problems, the research proposes a new framework that integrates advanced tools including machine learning, blockchain, and real-time updates about threats. The framework includes different features like automatic risk scoring and detection of unusual vendor behavior and keeping the secure digital records through the blockchain. This will highlight the need for the staff to …

Encapsulation Of Lactobacillus Reuteri Dsm 17938 In W/O/W Emulsion: Influence Of Oil Type On Viability And Oxidative Stability, Nora Mohamed Alantali

Theses

Probiotics, known for their wide range of health benefits, have been gaining recognition on their effects on the gut-brain axis. This axis, operated via various pathways, can be modulated by the type and functions of probiotics found in the gut microflora. However, probiotics face several stress factors before reaching the gut which hinders them from being functional. The main objective of this thesis was to construct a stable double-emulsion-based delivery system for probiotics, which can act as a barrier against the harsh conditions of the digestive system. Lactobacillus reuteri DSM 17938 was loaded in a water-in-oil-in-water Pickering double emulsion system, …

Section 276 Applications In Intimate Partner Sexual Assault Cases: The Impact Of R V Goldfinch, Janine Benedet, Isabel Grant

UBC Law Review

No abstract provided.

Enhancing Lawyers' Well-Being And Competencies Beyond The Traditional Law School Curriculum: The Impact Of Mindfulness Education On Law Students, Thomas G.W. Telfer, Emily G. Nielsen, Sara Ahola Kohut, Elli Weisbaum

UBC Law Review

No abstract provided.

58(1) Front Matter

UBC Law Review

No abstract provided.

The Effect Of Financial Literacy On Firm Performance, Erwin Joseph

Doctoral Dissertations (DBA)

This study examines the influence of financial literacy on firm performance by integrating state-level financial literacy data with firm-level metrics including Market Capitalization, Tobin’s Q, ROA, ROE, and EBIT. Utilizing data from the National Financial Capability Study (NFCS) and COMPUSTAT for the years 2009 to 2024, and a sample size of 100,126 observations, it highlights how higher levels of financial literacy correlate with improved firm valuation and profitability. The study employs the Financial Literacy Index and its imputed counterpart using the Fully Conditional Specification (FCS) method to address missing data. Regression analyses reveal that financial literacy significantly impacts both valuation …

Methane Mitigation And Its Effects On Energy Utilization In Lactating Dairy Cattle, Shan C. Sherwood

Department of Animal Science: Dissertations, Theses, and Student Research

Improved methane (CH₄) mitigation strategies are needed to achieve the greenhouse gas emission goals of the dairy industry. The first experiment was conducted to evaluate the effects of feeding black cumin (Nigella sativa) seed oil and acetate (BCA) on CH₄ production and whole-animal energy utilization. Twelve dry Jersey cows were used in a 2-period crossover design study with 28d periods. The BCA treatment was compared to a control diet with corn oil. Both BCA and corn oil were added to the base diet as a top dress. Results from this study did not show any …

Precision Feeding Methods To Increase Nitrogen And Energy Utilization In Lactating Dairy Cows, Chloe Emily Moss Harris

Department of Animal Science: Dissertations, Theses, and Student Research

The environmental and economic costs of overfeeding N to dairy cattle are a challenge in today’s dairy industry. Two studies were conducted to address new opportunities for precision feeding N, which is a strategy where producers strive to feed cows the precise amount of N and amino acids that meet their individual requirements.

The objective of the first study was to evaluate the effects of supplementing a rumen protected methionine (RPM) product via automatic milking system (AMS) concentrate on milk protein yield in lactating dairy cows. Fifty-one cows were randomly assigned to control (no RPM) or treatment groups. Milk yield …

Comparison Of Random Blood Sugar, Uric Acid, And Cholesterol Levels In Krangkeng Village With Karangjaladri Village, West Java, Indonesia, Rini Hendriani, Aria Aristokrat, Yuni E. Hadisaputri, Iyan Sopyan

Pharmacology and Clinical Pharmacy Research

The prevalence of metabolic diseases has increased over time, especially in Indonesia where 17.5% of the population suffers from metabolic syndrome. Metabolic diseases themselves are related to each other such as diabetes mellitus, gout, and dyslipidemia. One of the causes of metabolic diseases is environmental factors so this research aims to examine whether there was a relationship between metabolic diseases between two villages with different environmental conditions (Krangkeng Village and Karangjaladri Village). Data analysis used IBM SPSS Statistics 25 with random blood glucose, total cholesterol, and uric acid data taken using the Multi-Monitoring System Autocheck 3 in 1. The results …

Spartan Daily, May 1, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 164, Issue 40

Montana Residents' Attitudes Towards Tourism - 2024, Carter Bermingham, Megan Schultz, Matthew Pettigrew, Jayce Beck

Institute for Tourism and Recreation Research Publications

A summary of Montana residents' attitudes towards tourism from the 2024 season. Overall, results from this study show that, in general, Montana residents hold a positive yet balanced attitude towards tourism within the state. For example, a majority of residents feel that the benefits of tourism outweigh the negative impacts, while also being in strong agreement that tourism promotion by the state provides an economic benefit to their community. At the same time, over 40% of respondents felt that the state was becoming overcrowded because of the number of tourists, while close to half felt that their community was dealing …

Reuben Hersh's What Is Mathematics, Really? (Book Review), Calvin Jongsma

Faculty Work Comprehensive List

Reuben Hersh’s 1997 book What is Mathematics, Really? popularized a trend in the philosophy of mathematics that was gaining some traction at the time it was written. This essay examines Hersh’s work within the broader historical context of 19th- and 20th-century developments in mathematics and philosophy of mathematics. It also focuses on Hersh’s antagonism toward the influence of religion on (philosophy of) mathematics, concluding by briefly considering two positions taken by Christian mathematicians associated with ACMS in defense of such a connection.

Repair Through Recycling, Emma Murdock, Karl Aspelund

Senior Honors Projects

Repair Through Recycling is an instructional website I developed to encourage people to mend their garments rather than throw them away.I see this as a way to help address the growing issue of textile waste, where millions of garments are discarded each year. Many of these are made from synthetic materials that do not break down, contributing significantly to environmental pollution. This project features step-by-step instructional videos I created to teach the basics of mending, skills that are no longer commonly taught. These tutorials cover foundational techniques such as threading a needle and hand-stitching torn seams. The website also includes …

The Power Of Music: Analyzing Expression Of Empathy In Music Lyrics Across Male Vs Female Artists, Victoria Boustani

Senior Honors Projects

No abstract provided.

Assessing Use Of Suicide Prevention And Awareness Training In Rhode Island Public Secondary Schools, Marisa A. Waycuilis

Senior Honors Projects

Suicide has become the second leading cause of death in adolescents in the United States (CDC, 2023). To prevent suicide among school-aged children, the state of Rhode Island enacted the Nathan Bruno and Jason Flatt Act (2021-H5353, 2021-S003) in July of 2021. The legislation requires teachers, students (Grade 6 through 12), and hired school personnel to be annually trained in suicide awareness and prevention. In addition, each public school district must adopt a policy addressing produces relating to suicide prevention, intervention, and postvention. This project aimed to evaluate the level of compliance with the Nathan Bruno and Jason Flatt Act …

Insights Into Cancer Awareness And Health Practices In Rural Kenya: A Cross-Sectional Study Of Esophageal, Breast, Prostate, Cervical, And Colorectal Cancers, Rosebella Iseme-Ondiek, Joseph Abuodha, Anthony Ngugi, Mansoor Saleh, Innocent Abayo

Population Health, East Africa

PURPOSE; In sub-Saharan Africa (SSA), there has been an epidemiologic transition from infectious diseases to noncommunicable diseases, including a projected doubling in incidence of cancer. Understanding the underlying factors driving this surge is crucial for designing effective strategies to mitigate the cancer burden. This study focuses on assessing knowledge, attitudes, screening practices, and health behaviors related to five most prevalent cancers in SSA: prostate, breast, cervical, esophageal, and colorectal—among a predominantly rural coastal population in Kenya.

MATERIALS AND METHODS ;We used a cross-sectional study design targeting 1,500 adult respondents randomly selected from an existing community health and demographic surveillance system. …

From Epithelium To Therapy: Transitional Cells In Lung Fibrosis, Sarah Y Shin, Jichao Chen, Irit Milman Krentsis, Yair Reisner, Rodeo Abrencillo, Rahat Hussain, Danielle Wu, Harry Karmouty-Quintana

Faculty, Staff and Student Publications

Patients with idiopathic pulmonary fibrosis and lung fibrosis secondary to infections such as influenza A and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have limited treatment options outside of supportive therapy and lung transplantation. Multiple lung stem cell populations have been implicated in the pathogenesis of lung fibrosis, and more progenitor cell populations continue to be discovered and characterized. In this review, we summarize the functions and differentiation pathways of various cells that constitute the lung epithelium. We then focus on two subpopulations of KRT5

Safety, Efficacy, And Adjacent-Level Fracture Risk Following Vertebral Augmentation And Radiofrequency Ablation For The Treatment Of Spine Metastases In Patients With Cancer, Jeremiah Stringam, Koustav Pal, Andrew Niekamp, Rahim Jiwani, Iwan Paolucci, Joshua D Kuban, Zeyad Metwalli, Steven Huang, Peiman Habibollahi, Stephen Chen, Steven Yevich, Milan Patel, Sumit K Subudhi, Matthew Campbell, Amol Ghia, Claudio Tatsui, Rahul A Sheth

Faculty, Staff and Student Publications

Purpose: To evaluate the safety and efficacy of vertebral augmentation (VA) and radiofrequency ablation (RFA) for treating pathologic spinal fractures in patients with cancer and adjacent fracture risk following treatment.

Materials and Methods: This single-institution retrospective study, conducted from January 2017 to September 2020, included patients with cancer who underwent percutaneous VA with or without spine RFA for pathologic spine compression fractures. The primary outcome was pain reduction, assessed using the 10-point visual analog scale before the procedure, at first follow-up, and 2–4 weeks after the procedure. Logistic regression was performed to identify factors associated with epidural cement leak.

Results: …

Pd-L1 Testing, Treatment Patterns, And Clinical Outcomes Among Patients With Metastatic Nsclc At An Academic Medical Center, 2017-2021, Mehmet Altan, Dawen Sui, Cai Xu, George R Simon, Saliha T Sulihem, Donna Malveaux, Darcy Ponce, Waree Rinsurongkawong, Vadeerat Rinsurongkawong, J Jack Lee, Jianjun Zhang, Don L Gibbons, Ara A Vaporciyan, John V Heymach, Melissa L Santorelli, Thomas Burke, Loretta A Williams

Faculty, Staff and Student Publications

Introduction: Targeted therapies and immune checkpoint inhibitors (ICIs) have revolutionized the management of metastatic non-small cell lung cancer (NSCLC) over the past decade.

Methods: This single-center observational study was conducted to describe programmed death-ligand 1 (PD-L1) testing, choice of therapy, and outcomes for adult patients with stage IV NSCLC initiating first-line therapy from 2017 through 2020, with follow-up through June 2021. Patient characteristics and study assessments were described according to four histomolecular subtypes, defined by histologic characteristics and availability of standard-of-care therapies for molecular subgroups at the time of study conduct.

Results: Of 507 eligible patients with metastatic NSCLC, 85 …

The Multilayered Transcriptional Architecture Of Glioblastoma Ecosystems, Masashi Nomura, Avishay Spitzer, Kevin C Johnson, Luciano Garofano, Djamel Nehar-Belaid, Noam Galili Darnell, Alissa C Greenwald, Lillian Bussema, Young Taek Oh, Frederick S Varn, Fulvio D'Angelo, Simon Gritsch, Kevin J Anderson, Simona Migliozzi, L Nicolas Gonzalez Castro, Tamrin Chowdhfury, Nicolas Robine, Catherine Reeves, Jong Bae Park, Anuja Lipsa, Frank Hertel, Anna Golebiewska, Simone P Niclou, Labeeba Nusrat, Sorcha Kellet, Sunit Das, Hyo Eun Moon, Sun Ha Paek, Franck Bielle, Alice Laurenge, Anna Luisa Di Stefano, Bertrand Mathon, Alberto Picca, Marc Sanson, Shota Tanaka, Nobuhito Saito, David M Ashley, Stephen T Keir, Keith L Ligon, Jason T Huse, W K Alfred Yung, Anna Lasorella, Roel G W Verhaak, Antonio Iavarone, Mario L Suvà, Itay Tirosh

Faculty, Staff and Student Publications

In isocitrate dehydrogenase wildtype glioblastoma (GBM), cellular heterogeneity across and within tumors may drive therapeutic resistance. Here we analyzed 121 primary and recurrent GBM samples from 59 patients using single-nucleus RNA sequencing and bulk tumor DNA sequencing to characterize GBM transcriptional heterogeneity. First, GBMs can be classified by their broad cellular composition, encompassing malignant and nonmalignant cell types. Second, in each cell type we describe the diversity of cellular states and their pathway activation, particularly an expanded set of malignant cell states, including glial progenitor cell-like, neuronal-like and cilia-like. Third, the remaining variation between GBMs highlights three baseline gene expression …

Deciphering The Longitudinal Trajectories Of Glioblastoma Ecosystems By Integrative Single-Cell Genomics, Avishay Spitzer, Kevin C Johnson, Masashi Nomura, Luciano Garofano, Djamel Nehar-Belaid, Noam Galili Darnell, Alissa C Greenwald, Lillian Bussema, Young Taek Oh, Frederick S Varn, Fulvio D'Angelo, Simon Gritsch, Kevin J Anderson, Simona Migliozzi, L Nicolas Gonzalez Castro, Tamrin Chowdhury, Nicolas Robine, Catherine Reeves, Jong Bae Park, Anuja Lipsa, Frank Hertel, Anna Golebiewska, Simone P Niclou, Labeeba Nusrat, Sorcha Kellet, Sunit Das, Hyo-Eun Moon, Sun Ha Paek, Franck Bielle, Alice Laurenge, Anna Luisa Di Stefano, Bertrand Mathon, Alberto Picca, Marc Sanson, Shota Tanaka, Nobuhito Saito, David M Ashley, Stephen T Keir, Keith L Ligon, Jason T Huse, W K Alfred Yung, Anna Lasorella, Antonio Iavarone, Roel G W Verhaak, Itay Tirosh, Mario L Suvà

Faculty, Staff and Student Publications

The evolution of isocitrate dehydrogenase (IDH)-wildtype glioblastoma (GBM) after standard-of-care therapy remains poorly understood. Here we analyzed matched primary and recurrent GBMs from 59 patients using single-nucleus RNA sequencing and bulk DNA sequencing, assessing the longitudinal evolution of the GBM ecosystem across layers of cellular and molecular heterogeneity. The most consistent change was a lower malignant cell fraction at recurrence and a reciprocal increase in glial and neuronal cell types in the tumor microenvironment (TME). The predominant malignant cell state differed between most matched pairs, but no states were exclusive or highly enriched in either time point, nor was there …

Further Delineation Of The Scaf4-Associated Neurodevelopmental Disorder, Cosima M Schmid, Anne Gregor, Anna Ruiz, Carmen Manso Bazús, Isabella Herman, Farah Ammouri, Urania Kotzaeridou, Vanda Mcniven, Lucie Dupuis, Katharina Steindl, Anaïs Begemann, Anita Rauch, Aude-Annick Suter, Bertrand Isidor, Sandra Mercier, Mathilde Nizon, Benjamin Cogné, Wallid Deb, Thomas Besnard, Tobias B Haack, Ruth J Falb, Amelie J Müller, Tobias Linden, Chad R Haldeman-Englert, Charlotte W Ockeloen, Francesca Mattioli, Alexandre Reymond, Nazia Ibrahim, Shagufta Naz, Elodie Lacaze, Jennifer A Bassetti, Julia Hoefele, Theresa Brunet, Korbinian M Riedhammer, Houda Z Elloumi, Richard Person, Fanggeng Zou, Juliette J Kahle, Kirsten Cremer, Axel Schmidt, Marie-Ange Delrue, Pedro M Almeida, Fabiana Ramos, Siddharth Srivastava, Aisling Quinlan, Stephen Robertson, Eva Manka, Alma Kuechler, Stephanie Spranger, Malgorzata J M Nowaczyk, Reem M Elshafie, Hind Alsharhan, Paul R Hillman, Leslie A Dunnington, Hilde M H Braakman, Shane Mckee, Angelica Moresco, Andrea-Diana Ignat, Ruth Newbury-Ecob, Guillaume Banneau, Olivier Patat, Jeffrey Kuerbitz, Susan Rzucidlo, Susan S Sell, Patricia Gordon, Sarah Schuhmann, André Reis, Yosra Halleb, Radka Stoeva, Boris Keren, Zainab Al Masseri, Zeynep Tümer, Sophia Hammer-Hansen, Sofus Krüger Sølyst, Connolly G Steigerwald, Nicolas J Abreu, Helene Faust, Amica Müller-Nedebock, Frédéric Tran Mau-Them, Heinrich Sticht, Christiane Zweier

Faculty, Staff and Student Publications

While mostly de novo truncating variants in SCAF4 were recently identified in 18 individuals with variable neurodevelopmental phenotypes, knowledge on the molecular and clinical spectrum is still limited. We assembled data on 50 novel individuals with SCAF4 variants ascertained via GeneMatcher and personal communication. With detailed evaluation of clinical data, in silico predictions and structural modeling, we further characterized the molecular and clinical spectrum of the autosomal dominant SCAF4-associated neurodevelopmental disorder. The molecular spectrum comprises 25 truncating, eight splice-site and five missense variants. While all other truncating variants were classified as pathogenic/likely pathogenic, significance of one C-terminal truncating variant, one …

Beyond The Label Campaign: An Integrated Marketing And Communications Campaign To Educate And Empower Low-Income Communities In The Southern United States, Erica Napuli

Honors Program: Senior Projects (Public)

The Beyond the Label campaign is an Integrated Marketing Communications (IMC) initiative designed to educate and empower low-income consumers about food additives, labeling regulations and the impact of making educated food choices on long-term health. This campaign is based on research on current U.S. food labeling and regulations, health risks associated with current ingredients and additives approved through regulations, the disproportionate impact of food policy on low-income communities with a focus on the Southern U.S., as well as further exploration of strategies for multi-channel marketing for targeted audiences. This project proposes a hypothetical partnership with the Environmental Working Group (EWG). …