Digital Commons Network^™

From Imaging To Computational Domains For Physics-Driven Molecular Biology Simulations: Hindered Diffusion In Platelet Masses, Catherine House, Ziyi Huang, Kaushik Shankar, Sandra Young, Meghan Roberts, Scott Diamond, Maurizio Tomaiuolo, Timothy Stalker, Lu Lu, Talid Sinno

Cardeza Foundation for Hematologic Research

When formed in vivo, murine hemostatic thrombi exhibit a heterogeneous architecture comprised of distinct regions of densely and sparsely packed platelets. In this study, we utilize high-resolution electron microscopy alongside machine learning and physics-based simulations to investigate how such clot microstructure impacts molecular diffusivity. We used Serial Block Face - Scanning Electron Microscopy (SBF-SEM) to image select volumes of hemostatic masses formed in a mouse jugular vein, producing high-resolution 2D images. Images were segmented using machine learning software (Cellpose), whose training was augmented by manually segmented images. The segmented images were then utilized as 2D computational domains for Lattice Kinetic …

A Preliminary Examination Of The Effects Of Moral Elevation On Pain Tolerance, Pain Severity, And Interpersonal Goals, Candice Hayden

Clinical Psychology Dissertations

Despite the abundance of chronic pain treatment research, chronic pain continues to affect an estimated 20% of the world's population; thus, new approaches are likely needed to expand treatment options. One innovative approach to managing chronic pain distress is moral elevation. Moral elevation is an emotion experienced after witnessing an act of virtue, often described as a feeling of being uplifted, inspired, or in awe. Moral elevation has been linked with positive health-related outcomes such as improved mental health symptoms and higher physical quality of life, as well as higher social functioning such as prosocial behavior and a greater sense …

African American Women's Lived Experience Of The Process And Outcomes Of Psychotherapy For Depression, Eva Coleman Springs

Walden Dissertations and Doctoral Studies

The study of individuals’ experiences in psychotherapy has resulted in improvements in delivery of services to clients. The purpose of the current study was to use Aragon’s primary provider theory as the theoretical foundation to explore African American women’s perceptions of the process and outcomes of their psychotherapy for depression. Phenomenological methodology was used to explore a sample of nine African American women’s perceptions of the process and outcomes of their psychotherapy for depression and other mental health issues. Participants answered nine semi-structured interview questions to describe their experiences of at least one session of psychotherapy in the 2023 calendar …

Designing A Quality Principal Preparation Program: Key Features Of An Online Program, Alejandro Garcia, Rosalinda Hernandez

Organization and School Leadership Faculty Publications

This qualitative study examines the key characteristics of an online principal preparation program at a higher education institution. The analysis uncovered three significant features 1) Faculty and Curriculum approaches that respect various theoretical frameworks and methodologies; 2) Administrative and Structural elements that enhance accessibility and engagement; and 3) Additional Support Services that strengthen connection and community among participants.

Convergent Reduction Of Olfactory Genes And Olfactory Bulb Size In Mammalian Species At Altitude, Allie M Graham, Elysia Saputra, Bogdan Kirilenko, Jason S Presnell, Arianna Harrington, Chad Huff, Michael Hiller, Nathan Clark

Faculty, Staff and Student Publications

The invasion of specialized ecological niches can cause drastic changes to selection regimes, resulting in genomic and phenotypic transformation.

Do First Impressions Count? A Gendered Comparative Analysis Of Self-Presentations By Contestants In The Bachelor And Bachelorette South Africa, Mthobeli Ngcongo Dr

The Qualitative Report

The study of social role expectations for men and women has been instrumental in a better understanding of intersex dynamics. Although much research has focused on behavioral similarities and differences in formal contexts, qualitative research that helps us to understand gendered differences in informal contexts remains underappreciated. In particular, the area of romance presents a fruitful social context in which to comparatively study gendered manifestations of strategic self-presentation. Using the first episodes of the first seasons of the Bachelor and Bachelorette South Africa reality television franchise, this study compares 28 self-presentation tactics used by 17 male and 24 female contestants. …

Interviewing Refugees And Asylum Seekers: Study Guidelines For Forced Migration Researchers, Ahmad Al Ajlan

The Qualitative Report

This study develops guidelines for conducting qualitative research with refugees and asylum seekers in Western host countries by examining how participants' vulnerabilities should inform research practices. The guidelines are derived from a critical review of literature on qualitative research with vulnerable groups, particularly refugees, and the author's experience as a forced migration researcher with a displacement background. The study underscores how asylum seekers' vulnerabilities, shaped by acculturation challenges and exposure to trauma in their countries-of-origin, during their asylum journeys, and in host societies, influence both the interview process and the dissemination of findings. Key recommendations emphasize the need to account …

Use Of An Electronic Medication Management Application To Support Pharmacists Review To Optimise Medicines In Residential Aged Care (Prompt-Rc): A Study Protocol For A Parallel Cluster Randomised Controlled Trial, Amy Theresa Page, Dee Mangin, Hend Almutairi, Esa Y.H. Chen, Kenneth Lee, Nagham Ailabouni, Jacinta Johnson, Kathleen Potter, Nahal Mavaddat, Rhonda Marise Clifford, Elton Lobo, Loretta Baldassar, Liza Seubert, Dennis Petrie, Kate Wang, Sarah Hosking, Jenny Tasker, Christopher Etherton-Beer

Research outputs 2022 to 2026

Introduction Most older adults living in residential aged care facilities (RACFs) have at least one marker of potentially suboptimal prescribing. Pharmacists play a crucial role in medication management, with their effectiveness enhanced by using computerised decision support tools. The Pharmacists Review to Optimise Medicines in Residential Aged Care (PROMPT-RC) study aims to optimise medicine use by providing pharmacists in RACFs with an electronic medicine management app with integrated decision support (AusTAPER App/Pathway) to use as part of medication reviews they undertake. Methods and analysis The PROMPT-RC study is a parallel cluster randomised controlled trial design involving Australian RACFs. It will …

Perceptions To Care, (Education) And Treatment Reviews (C(E)Trs) Of Mental Health Clinicians Working With Adults With Intellectual Disability In England: A Cross-Sectional Study, Rohit Shankar

Peninsula Medical School

Introduction: Care (Education) and Treatment Reviews (C(E)TR)are meetings to review individualized needs of people withintellectual disabilities (PwID) at risk of or currently undergoingpsychiatric hospitalization. We aimed to understand C(E)TRimpact and effectiveness from professionals working with PwID.Methods: An online mixed-methodology survey whichincluded 34 questions (either Likert or free text) was sharedwith networks including relevant professionals. Quantitativedata are presented descriptively. Thematic analysis was conducted on free-text responses.Results: Of 66 people representing multiple intellectual disability teams across the UK, 67% found the C(E)TR process useful,35% felt C(E)TRs made a difference to their clinical care, while36% felt it did not. Thematic analysis showed four …

Integrating Ai In Academia: A Sem Evaluation Of Research Scholars Usage Intentions On Chatgpt, Sonal Sharma Phd, V. P. Joshith Phd, K Kavitha Med, Anusha Anthony Med

Higher Learning Research Communications

Objectives: In this study, we investigate the intentions of research scholars to use ChatGPT in their academic research endeavors by employing an extended Unified Theory of Acceptance and Use of Technology model, the UTAUT2, which examines factors such as performance expectancy, effort expectancy, social influence, facilitating conditions, hedonic motivation, habit, ethical concerns, and research excellence. By incorporating “research excellence” into the model, we aim to provide insights into artificial intelligence (AI) adoption in academic research settings and contribute to the broader discourse on the future of academic practices.

Method: We conducted a survey among 400 research scholars in Indian higher …

Moral Judgment Toward Individuals In Consensually Non-Monogamous Relationships As A Function Of Moral Foundations And Disgust Sensitivity, Dylan Selterman, Jeff Bowen, Ria Datwani, Amy C. Moors

Psychology Faculty Articles and Research

In two experiments we demonstrate how participants perceive individuals in consensually non-monogamous relationships (e.g., polyamory) more negatively compared to those in monogamous relationships, as a function of moral foundation variables and trait-level disgust sensitivity. In Study 1, we experimentally presented participants with vignettes depicting characters in one of two relationship types (monogamous or non-monogamous), after which participants completed character judgments (ethics) and relationship impressions. Participants viewed the characters in a monogamous relationship as more ethical and having higher relationship quality, and these associations were fully mediated by perceptions of the characters as pure, loyal, caring, fair, and honest. Participants high …

Dr Kinase: Predicting The Drug-Resistance Hotspots Of Protein Kinases, Shaofeng Lin, Chao Tu, Ruifeng Hu, Haiji Wang, Zongcheng Dong, Hui Luo, Lan Kuang, Tao Wang, Liming Wang, Zhongming Zhao, Zhihong Li, Haodong Xu

Faculty, Staff and Student Publications

Protein kinases (PKs) regulate various cellular functions, and are targeted by small-molecule kinase inhibitors (KIs) in cancers and other diseases. However, drug resistance (DR) of KIs occurs through critical mutations in four types of representative hotspots, including gatekeeper, G-loop, αC-helix, and A-loop. KI DR has become a common clinical complication affecting multiple cancers, targeted kinases, and drugs. To tackle this challenge, we report an upgraded web server, namely Dr. Kinase, for predicting the loci of four DR hotspots and assessing effects of mutations on DR hotspots for PKs in our previous studies, by utilizing multimodal features and deep hybrid learning. …

Consideration Of Patient Phenotypes In Geographic Atrophy Due To Age-Related Macular Degeneration, Rishi P Singh, Christina Y Weng, John W Kitchens, Jaclyn Quilantan, Roy Schwartz, Caroline R Baumal, Roger A Goldberg

Faculty, Staff and Students Publications

Geographic atrophy (GA) is a form of advanced age-related macular degeneration (AMD) affecting approximately 1 million people in the USA and 5 million globally. In this review, retinal imaging techniques used for diagnosis and monitoring progression of GA in AMD, and the risk factors associated with the development and progression of GA are summarised. To familiarise clinicians with common phenotypes of patients with GA, the clinical and imaging features that may lead to rapid progression of GA in various phenotypes are highlighted. With the recent US Food and Drug Administration approval of new GA treatments that reduce lesion growth, understanding …

Being Well: Stories Of Coping And Resilience, Simiao Li-Sauerwine, Abbas Husain, Al'ai Alvarez, Gillian Baty, Manish Garg, Ryan Bodkin, Andy Grock, Marc Borenstein, Pamela Dyne

Journal of Wellness

Introduction: The approach to physician well-being has transformed from a focus on identification of distress to embracing a comprehensive model that values vulnerability, growth, self-compassion, and a sense of purpose and community in the profession. This manuscript, a collaborative effort by the Council of Residency Directors in Emergency Medicine Well-being Committee and the Society for Academic Emergency Medicine Wellness Committee, presents the personal narratives of academic emergency physicians during which they faced challenges and stressors, as well as supportive resources they found helpful. The scenarios are written by the individuals themselves as they experienced them.

Discussion: Through these shared and …

Acquiring Assets By Purchasing Corporate Stock (Part Ii), Edward J. Schnee

Tax Adviser

No abstract provided.

Tax Trends, E. S. Linett

Tax Adviser

No abstract provided.

Tax Trends, E. S. Linett

Tax Adviser

No abstract provided.

Exploring Relationships Between Racial Bias, State Empathy, And Perceived Recovery Time Following A Medical Hardship, Kabe Aberle, Lydia Gengler, Madelyn Kavalieros, Brookelyn Mayfield, Kevin M. Summers, Sarah Huff

DU Undergraduate Research Journal Archive

This experiment investigated whether racial biases exist in laypeople's perceptions of recovery time following a common, medically-related hardship and whether these biases can be explained by differential empathy across race. White participants (n=133) read a vignette describing either a White or Black target who experienced a minor car accident. They then rated the amount of time they felt was reasonable for the target to take off from work and normal activities and how much time it would take to recover physically and mentally. Participants also completed measures of state empathy toward the target and their sleep quality. Results …

Massacre Vs. Shooting: Exploring Cnn And Fox’S Coverage Of The Uvalde Robb Elementary School Attack, Maya Beesley

DU Undergraduate Research Journal Archive

This study dissects FOX News Media (FOX News) and Cable News Network’s (CNN) media coverage differences of the Uvalde, Texas Robb Elementary School terror attack (Uvalde shooting). On March 24, 2022, Salvador Ramos perpetrated a mass shooting, killing 19 children and two teachers and injuring 17 others. This paper showcases that the incident qualifies as terrorism and explores how two major U.S. news outlets framed and covered the incident differently in their headlines, images, captions, sources, and tone. While CNN emphasized police culpability, victim perspectives, and presented a somber tone, FOX News downplayed the severity of the attack, highlighted police …

Du Undergraduate Showcase Abstracts: Research, Scholarship, And Creative Works, Kabe Aberle, Nadia Kako, Kateri Mcrae, Brooke Agulnek, Sky Palmon, Yasmine Ramirez, Francisca Aguirre Beltran, Ashley Juarez, Bridget Kim, Tessa Appel, Sterling Kerr, Spencer Ingley, Gabe Meyer, Robin Tinghitella, Dale Broder, Lily Baeza, Chloe Beers, Julia Coakley, Whitney Kelsey, Sydney Gainforth, Gabi Wing, Audrey Martin, Aaliyah Amore Berry, Brooke Watley, Kiruthika Venkatesan, Rachel Bienstock, Annabella Brotherston, Madison Bryant, Mia Burgener, Emma P. Lieb, Rachel A. Johnson, Jennifer L. Hoffman, Kania Campbell, Kiena Campbell, Courtney Cassidy, Sage Krzyzkowski, Maddox Jones, Skylar Abookire, Luke Hawkins, Sunnah Yoon, Andrea Chu, Yan Qin, Nyah Cubbison, Brian Gearity, Daniel Mcintosh, Mariely Cruz, Edward Garrido, Grady Dionne, Nicole Doris, Lyndsie Salvagio, Ann-Charlotte Granholm-Bentley, Anna Dymov, Hannah Eckert, Gabrielle Welsh, Erica Larson, Charlie Ernst, Anna Zhou, Sarah Watamura, Larissa Fedorovich-Klein, Georgie Fields, Kimberly A. Guevara, Aven Mccall, Ben Peltier, Feruz Yahia, Patrick Flores, Jadyn Floyd, Sophia Forcier, J. Von R. Monteza, Peter Sokol-Hessner, Gwendolyn Geiger, Scott Nichols, Camryn Gunter, Kendal Hengst, Charlie Bednarz, Issy Garside, Addison Baker, Rachel Mina, Brooke Hermanson, Amanda Klingler, William Highfill, Sydney Jaques, Kerstin Lewey, Allison Grossery, Daniel Linseman, Ethan Lim, Jagger Livengood, Owen Mantelli, Gabby Pappas, Abby Mcdonald, Madeleine Dierking, Eve Miller, Emma Loeber, Anna Marlow, Michael Kerwin, Ella Mathews, Hillary Hamann, Khadija Mohamed, Vivian Nguyen, Gabri Notov, Ifunayachi Ogbonna-Ukuku, Sunil Kumar, Charles Baysah, Sarah Olson, Don Sullivan, Anna Paradiso, Jay Parrish, Mira Pronobis, Alisha Pravasi, Kerstin Haring, Diego Ramirez, Christopher Reardon, Juliana Ramirez, Casey Doherty, Ella Kestner, Teagan Weindel, Cate Billings, Pablo Torre-Walter, Lucy Rand, Samantha Reynolds, Mark Siemens, Khadeeja Rashid, Laine Satterlee, Piper Heilbronner, Lily Pound, Ben Whitehurst, Anna Respet, Lizzie Lesoing, Sydney Hertel, Aya Saad-Masri, Brooke Ballenger, Max Proske, Hannah Rosenberg, Ellia Nakahara, Sophia Espinoza, Ivan Woolhouse, Simon Ruland, Gorkem Er, Timothy Sweeny, Melaku Saketa, Michela Schenk, Maren Lynch, Madi Hamm, Grace Schroeder, Michelle Rozenman, Rana Seif, Jackson Hall, Marisela Simental, Daniel Paredes, Aaron Mena, Preston Spaan, Evelyn Stovin, David Andrew Swartz, Anh Tran, Daniel Pittman, Luke Farchione, Emily Boyer, Ukari Verner, Lacey Conrad, Jonathan Velotta, James Weiner, Jagger Gossett, Noah Sherry, Sam Proud, Ben Block, Avi Narayana, Zoey Weiss, Alyssa Wilson, Gabrielle Walsh, David Zonana, Keely Wright, Kena Riveria, Lillybelle Deer, Jena Doom, Elysia Davis, Isabelle Yaremenko, Caitlyn Young

DU Undergraduate Research Journal Archive

Abstracts from the DU Undergraduate Research Showcase.

Pharmacy School Expands Global Reach Through Faculty Exchange In Japan, Marisa C. Atkinson

University of Mississippi News

OXFORD, Miss. – University of Mississippi pharmacy professor Adam Pate recently showcased and shared his knowledge and experience with an international audience in Japan.

Cheating With The Fifth Amendment: Weaponizing The Fifth Amendment Privilege To Undermine Equitable Dissolution Of Marriages, Elizabeth I. Boals

Loyola of Los Angeles Law Review

Despite widespread adoption of no-fault divorce, many U.S. states still consider adultery in the allocation of alimony and property. In sixteen of those states, adultery remains a criminal offense—enabling spouses accused of infidelity to invoke the Fifth Amendment privilege against self-incrimination during divorce proceedings. This Article explores how such invocations obstruct discovery, delay litigation, and create strategic advantages for wealthier or culpable spouses, especially in fault-based or hybrid divorce regimes. After surveying the historical development of divorce law and the expansion of Fifth Amendment protections into civil contexts, the Article critiques current remedies—adverse inferences, implied waivers, and immunity—as ineffective or …

Coordinating Instruments For Multi-Messenger Astrophysics, Daisy Wang, Ye Htet, Marion Sudvarg, Roger Chamberlain, Jeremy Buhler, James Buckley

Computer Science Faculty Research & Creative Works

In multi-messenger astrophysics, signals of multiple types (e.g., gravitational waves, neutrinos, electromagnetic waves) are combined in an effort to learn more about the observed phenomena of interest. The Advanced Particle-astrophyics Telescope (APT) is a mission concept for a space-borne instrument that detects gammaray bursts (GRBs) omnidirectionally, facilitating multi-messenger observations by identifying and localizing celestial events of interest. Here, we describe the on-instrument computations for APT and its Antarctic Demonstrator (ADAPT) as well as techniques for follow-up observations of transient events.

Mutual Position Of Two Smooth Quadrics Over Finite Fields, Shamil Asgarli, Chi Hoi Yip

Mathematics and Computer Science

Given two irreducible conics C and D over a finite field 𝔽_q with q odd, we show that there are q²/ 4 + O(q^3/2) points P in P²(𝔽_q) such that P is external to C and internal to D. This answers a question of Korchmáros. We also prove the analogous result for higher-dimensional smooth quadric hypersurfaces in P^n-1  with n odd, where the answer is q^n-1/4 + O(q^n-3/2).

Hacking Generative Ai, Ido Kilovaty

Loyola of Los Angeles Law Review

Generative AI platforms, like ChatGPT, hold great promise in enhancing human creativity, productivity, and efficiency. However, generative AI platforms are prone to manipulation. Specifically, they are susceptible to a new type of attack called “prompt injection.” In prompt injection, attackers carefully craft their input prompt to manipulate AI into generating harmful, dangerous, or illegal content as output. Examples of such outputs include instructions on how to build an improvised bomb, how to make meth, how to hotwire a car, and more. Researchers have also been able to make ChatGPT generate malicious code.

This Article asks a basic question: do prompt …

Conflicting Social Information And Its Impact On Sentence Comprehension In Young Adults With Dld: An Eye Tracking Study, Ansley Davis

USF Tampa Graduate Theses and Dissertations

Individuals must recognize linguistic and non-linguistic social cues to resolve contextual ambiguities in their conversations. When the linguistic and social cues match, sentence processing is facilitated. However, conflicts between linguistic and social stimuli (i.e., incongruency) can lead to prediction errors which slow sentence processing. Limited research has explored the social cognition conflict resolution skills in individuals with Developmental Language Disorder (DLD) despite their documented emotion processing deficits. This study considers the role of social prediction processing in adults with DLD as they engage in a social cognition conflict resolution task.

Young adults with DLD (n=29) and typically developing (TD) peers …

Community Health Workers: Key To Decreasing Food Insecurity In Pregnant Individuals, Linda Waggener Dnp

Doctor of Nursing Practice Scholarly Projects

Objectives: Food insecurity (FI) in pregnant individuals (PI)s is a global threat to birthing individuals and fetuses with potential immediate and intergenerational impacts on family and community. Community Health Workers (CHWs) facilitate support including food resources for FIPIs. The Family Fresh Rx (FFRx) program, within Food as Medicine (FaM) model provides fresh fruits and vegetables, optimize nutrition, and mitigates threats to health. This Doctor of Nursing Practice (DNP) Quality Improvement (QI) project’s two objectives were CHWs’ FFRx program and referral process satisfaction evaluation through a pre, post, and four-week post refresher presentation (RP) modified System Usability Scale (mSUS) …

Educating Healthcare Providers To Prevent And Mitigate The Effects Of Zoom Fatigue, Andrea Lima

Doctor of Nursing Practice Scholarly Projects

Zoom Fatigue (ZF), or physical and neuropsychological responses to excessive videoconferencing (VC), increased during the COVID-19 pandemic. Like burnout, ZF can compromise patient safety by causing decreased job satisfaction, social isolation, disrupted focus, and difficulty empathizing with patients. This Plan-Do-Study-Act quality improvement project aimed to assess feelings about VC, raise awareness of the adverse effects of overuse, and empower primary care providers (PCPs) to improve their work experiences. A group of on-site PCPs at a tertiary care medical center in the Southwest, who continued holding exclusive virtual team meetings after the pandemic, was asked to complete the 15-question Zoom Exhaustion …

Speak Now With The Courage To Confront: An Educational Intervention To Address Bullying, Dominique Desiree Gomez

Doctor of Nursing Practice Scholarly Projects

Abstract

Background: Nurse-to-nurse bullying is a critical issue within the nursing profession, impacting close to half of all nurses. This phenomenon, articulated by the phrase "nurses eat their young," detrimentally influences employee retention, job satisfaction, morale, and ultimately, patient care. Furthermore, nurse-to-nurse bullying significantly affects the well-being of nursing professionals, particularly targeting novice nurses. This targeting raises substantial concerns regarding their retention, as many consider leaving the profession within their initial years of practice due to experiences of bullying. The educational intervention project titled “Speak Now with the Courage to Confront” is designed to mitigate bullying among novice nurses through …

Where The Fog Hangs: An Interview With Elaine Sheldon Mcmillion On Appalachia, Filmmaking, And The Power Of Small Acts, Elaine Mcmillion Sheldon, Scott C. Mcdaniel

Critical Humanities

An Interview with Elaine Sheldon McMillion