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Strategies To Improve Psychiatrist Understaffing In Psychiatric Hospitals In Rural And Underserved Communities: Addressing Administrative Challenges, Carla Aramouni Aug 2025

Strategies To Improve Psychiatrist Understaffing In Psychiatric Hospitals In Rural And Underserved Communities: Addressing Administrative Challenges, Carla Aramouni

Walden Dissertations and Doctoral Studies

Psychiatric hospitals across the United States face a worsening shortage of psychiatrists, particularly in rural and underserved communities, which limits timely mental health care, increases wait times, and places unsustainable strain on the psychiatric workforce. The purpose of this integrative review was to identify administrative strategies that can mitigate psychiatrist understaffing and support sustainable care delivery in psychiatric hospitals. An integrative review methodology was used to explore both empirical and nonempirical literature, resulting in 92 articles, including 32 peer-reviewed sources and several supporting studies selected through a systematic search, screening, and critical appraisal. Thematic analysis of the evidence revealed five …


An Investigation Of Parental Involvement In The Safe Passage Initiative (An Anti-Violence Program), Danielle King Aug 2025

An Investigation Of Parental Involvement In The Safe Passage Initiative (An Anti-Violence Program), Danielle King

Electronic Theses and Dissertations

This dissertation investigates the issue of parental involvement in Safe Passage, an anti-violence initiative operating within seven Pittsburgh Public Schools. Recognizing the involvement of parents is critical for successful violence prevention, this study explores the barriers hindering meaningful participation and identifies strategies to enhance parent-school-community collaboration.

Utilizing qualitative research methods, the study captures insights from parents, educators, and community stakeholders through a reflective Journey Line activity and focus group discussion. Data collected revealed several significant barriers such as inconsistent communication, limited parental availability due to demanding work schedules, mental and emotional exhaustion, cultural disconnects, and a lack of clarity regarding …


Sac Newsletter 2025, South Asia Center Aug 2025

Sac Newsletter 2025, South Asia Center

Newsletters from the South Asia Center

No abstract provided.


Humidity Control Apparatus And Materials, Ying Zhong Aug 2025

Humidity Control Apparatus And Materials, Ying Zhong

USF Patents

A ventilation port maintains the humidity range within a sealed or partially sealed enclosure maintaining a level of atmospheric moisture such as a greenhouse. The port is comprised of a polymer blend film made of a hydrophilic component serving as the water-absorbing material and substrate component serving as the mechanical backbone. The film is designed to bend and open the port when the humidity within the enclosure exceeds a predetermined level outside the humidity range, allowing for the venting of excess humidity. Once the humidity falls back within the desired range, the film returns to its original state and closes …


Mechanism Of Unconventional Il-33 Release In Airway Disease, Omar Osorio Aug 2025

Mechanism Of Unconventional Il-33 Release In Airway Disease, Omar Osorio

Arts & Sciences Graduate Student Theses and Dissertations

The alarmin cytokine IL-33 is a strong inducer of type two inflammation and has been implicated in various chronic lung diseases. Although much work has been done to understand the inflammatory effects of extracellular IL-33, there is still a knowledge gap in understanding how this cytokine is secreted by airway epithelial cells in steady-state conditions. In the work laid out in this document, a COPD-disease associated isoform of IL-33, that has exons 3 and 4 (IL-3334) spliced out and is tonically secreted at baseline conditions. This IL-33 isoform is secreted from airway epithelial cells alongside, or as part of, extracellular …


The Power Of Service Learning At Byu, Yoshihiko Ariizumi Aug 2025

The Power Of Service Learning At Byu, Yoshihiko Ariizumi

Spiritual Proficiency

This article summarizes the merits of Service Learning for university students.


Educating Nurses On The Agency Of Healthcare Research And Quality Pressure Ulcer Prevention Program To Reduce The Rate Of Pressure Ulcers, Marie France Destaul Aug 2025

Educating Nurses On The Agency Of Healthcare Research And Quality Pressure Ulcer Prevention Program To Reduce The Rate Of Pressure Ulcers, Marie France Destaul

Walden Dissertations and Doctoral Studies

A staff development project was conducted to address the practice problem encountered in a healthcare setting. The identified gap in practice was related to a lack of knowledge of pressure ulcer injury prevention among inpatient staff. Leadership deemed it essential to address this practice problem in nursing care because the prevalence of pressure ulcer injuries in hospitalized patients was high. The following practice-focused question guided the project: For staff in an inpatient setting, will education on the Agency of Healthcare Research and Quality (AHRQ) Pressure Ulcer Prevention Program increase knowledge toward the goal of decreasing the incidence of pressure ulcers? …


Nurse-Initiated Improvement For Documentation Of Penicillin Adverse Drug Reactions In Pediatric Urgent Care Clinics., Elizabeth Monsees, Diane Petrie, Rana El Feghaly, Sarah Suppes, Brian R. Lee, Megan Whitt, Amanda Nedved Aug 2025

Nurse-Initiated Improvement For Documentation Of Penicillin Adverse Drug Reactions In Pediatric Urgent Care Clinics., Elizabeth Monsees, Diane Petrie, Rana El Feghaly, Sarah Suppes, Brian R. Lee, Megan Whitt, Amanda Nedved

Manuscripts, Articles, Book Chapters and Other Papers

Background/Objective: Penicillin allergy labels (PALs) contribute to broad-spectrum antibiotic use. Thorough documentation can help prescribers identify and remove unnecessary PALs. We aimed to improve documentation of PALs in three pediatric urgent care (PUC) clinics, using a nurse-initiated quality improvement (QI) approach. Methods: QI interventions included a survey to assess prescriber and nurse confidence, an online educational module, and an algorithm to aid in clarifying PALs. We measured the percentage of PALs with a clarified reaction severity as our primary outcome using annotated control charts. Descriptive and inferential statistics evaluated survey responses between nurses and prescribers. Results: Clarified PAL reaction severity …


Canada’S Indigenous Social Workers’ Medicinal Plant Knowledge: A Land-Based Way Of Knowing For Indigenous Practice, Iris Kim Plain Eagle Aug 2025

Canada’S Indigenous Social Workers’ Medicinal Plant Knowledge: A Land-Based Way Of Knowing For Indigenous Practice, Iris Kim Plain Eagle

Walden Dissertations and Doctoral Studies

Canada’s Indigenous people of Treaty 7 region have experienced intergenerational trauma resulting from colonization perpetrated by the Canadian government. While the use of medicinal plants, are employed by Indigenous social workers, their integration into mainstream human services organizations remains limited. The gaps in Indigenous social work practice hinders client culturally competent care and the acknowledgement of Indigneous knowledge systems in colonial systems. This generic qualitative study explored the experiences of participants who integrate medicinal plant healing and ancestral knowledge into practice. Informed by indigenous wholistic theory, the study aimed to understand how Indigenous social workers navigate the challenges and opportunities …


Kraemer Is 2025 Distinguished Alumni Award Recipient, Communications And Marketing Aug 2025

Kraemer Is 2025 Distinguished Alumni Award Recipient, Communications And Marketing

Campus News Archive

No abstract provided.


Immunogenicity And Safety Of A Rabies-Based Highly Pathogenic Influenza A Virus H5 Vaccine In Cattle, Nir Paran, Christoph Wirblich, Catherine Olal, Alessandro Tarquinio, Kimberly H. Lohmeyer, Drishya Kurup, Stacey Schultz-Cherry, Ismaila Shittu, Gregory C. Gray, Dennis A. Bente, Pia U. Olafson, Matthias J. Schnell Aug 2025

Immunogenicity And Safety Of A Rabies-Based Highly Pathogenic Influenza A Virus H5 Vaccine In Cattle, Nir Paran, Christoph Wirblich, Catherine Olal, Alessandro Tarquinio, Kimberly H. Lohmeyer, Drishya Kurup, Stacey Schultz-Cherry, Ismaila Shittu, Gregory C. Gray, Dennis A. Bente, Pia U. Olafson, Matthias J. Schnell

Department of Microbiology and Immunology Faculty Papers

The circulation of highly pathogenic H5 influenza A viruses in cattle, other mammals, and wildlife threatens animal and human health. To address this, we vaccinated heifer-calves with a deactivated rabies-virus-based H5 vaccine, which was well-tolerated and elicited neutralizing antibodies against both clade-1 and clade-2.3.4.4b H5N1 viruses, comparable to naturally H5-infected and convalescing cows. The immune responses to the vaccine platform were durable for at least 200 days and unaffected by preexisting RABV immunity.


Women Veterans' Use Of Gender-Specific, Online, Social Support Systems For Social Identity After Military Service, Katie M. Baillio Aug 2025

Women Veterans' Use Of Gender-Specific, Online, Social Support Systems For Social Identity After Military Service, Katie M. Baillio

Walden Dissertations and Doctoral Studies

The number of women veterans serving in the military is growing. This qualitative study explored women veterans' perspectives and experiences with gender-specific online social support services, and how that contributes to their social identity after military service. A generic qualitative design was used, and data were collected through semistructured interviews for 10 women veterans who had transitioned out of the military within the last 5 years. Five themes emerged: (a) big picture: connecting with other women veterans was helpful; (b) veteran forums were used for federal or state benefits, but women used gender-specific forums for questions specific to women's issues; …


Conceptual Model And Design Of An Initiative To Build Nurses’ Resilience And Ethical Practice, Cynda Hylton Rushton, Sandra M. Swoboda, Nancy Reller, Laura C. Sarver, Erin M. Wright, Krysia Warren Hudson, Robie Victoria Hughes, Ginger C. Hanson, Rita D’Aoust Aug 2025

Conceptual Model And Design Of An Initiative To Build Nurses’ Resilience And Ethical Practice, Cynda Hylton Rushton, Sandra M. Swoboda, Nancy Reller, Laura C. Sarver, Erin M. Wright, Krysia Warren Hudson, Robie Victoria Hughes, Ginger C. Hanson, Rita D’Aoust

College of Nursing Faculty Papers & Presentations

Background: Healthcare faces a nursing crisis with high turnover, burnout, and faculty shortages, which requires innovative educational approaches that bridge the gap between education and practice. Purpose: To present the conceptual model and design of a statewide, trans-institutional academic-practice collaboration that holistically builds nurses' resilience and ethical practice across the education-to-practice continuum. Method: Development of the Renewal, Resilience, and Retention (R3) Initiative based on adaptation of the Mindful Ethical Practice and Resilience Academy (MEPRA), social ecological framework, and stakeholder input across eight schools of nursing and five hospitals in Maryland. Results: The R3 Initiative created a scalable …


Depaul Digest Aug 2025

Depaul Digest

DePaul Magazine

College of Communication faculty Matthew Ragas and Ron Culp mentor students on gaining access to executive-level administration. News briefs on exciting developments at DePaul University’s 10 colleges and schools, from nursing students studying public health protocols in Prague to a new DePaul-hosted conference exploring AI in filmmaking. DePaul alumni volunteers share their experiences spreading the Vincentian mission nationwide.


Full Issue: Summer 2025 Aug 2025

Full Issue: Summer 2025

DePaul Magazine

In DePaul Magazine's summer 2025 issue, we celebrate The Theatre School's centennial by asking past and present faculty and administrators and illustrious alumni to comment on the venerable institution's enduring legacy of hands-on learning, collaboration and critical dialogue. Plus, learn about the remarkable relationship between the School of Music and the Chicago Symphony Orchestra that connects music performance students to world-class musicians, see images of campus life snapped by a new student photo agency, and more.


Class Notes Aug 2025

Class Notes

DePaul Magazine

From promotions to performances, see the latest accomplishments by DePaul alumni across class years and generations. Plus, read alumni spotlight profiles of Steve Schmidt (CSH MS ’13), director of machine learning at Nike, and Sarah Brachle Wagner (LAS ’96), CEO of Chicagoland Habitat for Humanity.


Und Leads Implementation Team Meeting Agenda — August 19, 2025, University Of North Dakota Aug 2025

Und Leads Implementation Team Meeting Agenda — August 19, 2025, University Of North Dakota

LEADS Implementation Documents

Agenda for the August 19, 2025 meeting of the UND LEADS Implementation Team. The agenda includes subgroup reports and continued discussion of Learning recommendations, including practicality, impact, alignment, and connections with available data.


Effects Of Social Influences On Adult Male Politicians Who Engage In Sexually-Exploitative Behaviors, Rodshana M. Ulery Aug 2025

Effects Of Social Influences On Adult Male Politicians Who Engage In Sexually-Exploitative Behaviors, Rodshana M. Ulery

Walden Dissertations and Doctoral Studies

Sexually-exploitative behaviors by adult male politicians is a significant societal concern that reflects deeper issues involving power misuse, gender inequality, and institutional failure. This qualitative research involved examining societal factors that were linked with this type of misconduct. Guided by the status characteristics theory, the study involved examining how status-related traits such as political power, public image, and institutional affiliation shaped social dynamics and fostered environments that enabled these behaviors. Using NVIVO, thematic content analysis was applied to 24 adult male politician cases. Five key themes emerged: early life and family influences, position and power, opportunity expectations, cultural and institutional …


Teaching Bilingual Learners With Dysgraphia, Angela Gonzalez-Urbina Aug 2025

Teaching Bilingual Learners With Dysgraphia, Angela Gonzalez-Urbina

Masters Projects

With the push for legislation on the Dyslexia law in Michigan and elsewhere, teachers need to understand what dyslexia and dysgraphia are to support all students. An extra understanding is necessary in bilingual education and reading challenges because they use two language systems in and out of the classroom. Reading and writing are already areas that impact the working memory of the learner; adding dysgraphia to that proves to be more of a challenge. Dysgraphia can coexist with dyslexia, and individuals with dysgraphia often experience difficulties with spelling and writing speed. This project introduces dysgraphia as one of the reading …


Machine Learning Research On Time Series Data, Zeyi Fan Aug 2025

Machine Learning Research On Time Series Data, Zeyi Fan

Lingnan Theses (MPhil & PhD)

Time series generated by complex systems, such as industrial IoT and user behavior systems, confront two core challenges: structured missingness (e.g., continuous or periodic gaps) that disrupt temporal dependencies, and the difficulty in effectively modeling dynamic long- and short-term temporal dependencies inherent in evolving patterns (e.g., user interests). Traditional approaches struggle to balance the preservation of local dependency continuity and the rational association of global long-range dependencies in structured missing scenarios, often incurring high computational costs. In temporal pattern modeling, the lack of adaptive mechanisms to fuse evolving long- and recent behavior trends (e.g., stable interest inertia vs. short-term preference …


Causes Of Symptoms And Symptom Persistence In Long Covid And Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Anthony L Komaroff, Robert Dantzer Aug 2025

Causes Of Symptoms And Symptom Persistence In Long Covid And Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Anthony L Komaroff, Robert Dantzer

Faculty, Staff and Student Publications

Debilitating symptoms for many years can follow acute COVID-19 ("long COVID"), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and various post-acute infection syndromes (PAISs). Together, long COVID and ME/CFS affect 60-400 million individuals, globally. Many similar underlying biological abnormalities have been identified in both conditions including autoantibodies against neural targets, endothelial dysfunction, acquired mitochondrial dysfunction, and a pro-inflammatory gut microbiome. Each of these abnormalities may directly cause some of the symptoms. In addition, the symptoms also may be caused by ancient, evolutionarily conserved symptomatic and metabolic responses to vital threats-sickness behavior and torpor-responses mediated by specific, recently discovered neural circuits. These neural …


Quantifying Collective Interactions In Biomolecular Phase Separation, Hannes Ausserwöger, Ella De Csilléry, Daoyuan Qian, Georg Krainer, Timothy J Welsh, Tomas Sneideris, Titus M Franzmann, Seema Qamar, Nadia A Erkamp, Jonathon Nixon-Abell, Mrityunjoy Kar, Peter St George-Hyslop, Anthony A Hyman, Simon Alberti, Rohit V Pappu, Tuomas P J Knowles Aug 2025

Quantifying Collective Interactions In Biomolecular Phase Separation, Hannes Ausserwöger, Ella De Csilléry, Daoyuan Qian, Georg Krainer, Timothy J Welsh, Tomas Sneideris, Titus M Franzmann, Seema Qamar, Nadia A Erkamp, Jonathon Nixon-Abell, Mrityunjoy Kar, Peter St George-Hyslop, Anthony A Hyman, Simon Alberti, Rohit V Pappu, Tuomas P J Knowles

2020-Current year OA Pubs

Biomolecular phase separation is an emerging theme for protein assembly and cellular organisation. The collective forces driving such condensation, however, remain challenging to characterise. Here we show that tracking the dilute phase concentration of only one component suffices to quantify composition and energetics of multicomponent condensates. Applying this assay to several disease- and stress-related proteins, we find that monovalent ions can either deplete from or enrich within the dense phase in a context-dependent manner. By analysing the effect of the widely used modulator 1,6-hexanediol, we find that the compound inhibits phase separation by acting as a solvation agent that expands …


Corticotropin-Releasing Hormone Modulates Nrem Sleep Consolidation Through The Thalamic Reticular Nucleus, Loredana Cumpana, Olivia Zanoletti, Dinesh Kankanamge, Bryan Copits, Carmen Sandi, Simone Astori Aug 2025

Corticotropin-Releasing Hormone Modulates Nrem Sleep Consolidation Through The Thalamic Reticular Nucleus, Loredana Cumpana, Olivia Zanoletti, Dinesh Kankanamge, Bryan Copits, Carmen Sandi, Simone Astori

2020-Current year OA Pubs

Corticotropin-releasing hormone (CRH) is a peptide associated with stress and anxiety that acts as a potent modulator throughout the nervous system. The thalamic reticular nucleus (TRN) displays high expression of the CRH receptor 1 (CRHR1), but whether CRH modulates key TRN functions, such as sleep spindle rhythmogenesis, remained unexplored. Combining polysomnographic and photometric recordings in mice, we show that CRH release in TRN during non-rapid-eye movement sleep (NREMS) oscillates with a ~50-s periodicity, anti-correlating with sleep spindle dynamics. Optogenetic manipulations of CRH release in TRN modulated NREMS fragmentation through microarousals with corresponding changes in sigma and delta power. In ex-vivo …


O-Glcnac Transferase Plays Dual Antiviral Roles By Integrating Innate Immunity And Lipid Metabolism, Hong Dong, Yong Zhang, Michael J Holtzman, Et Al. Aug 2025

O-Glcnac Transferase Plays Dual Antiviral Roles By Integrating Innate Immunity And Lipid Metabolism, Hong Dong, Yong Zhang, Michael J Holtzman, Et Al.

2020-Current year OA Pubs

Viral infection induces robust reprogramming of metabolic pathways in host cells. However, whether host metabolic enzymes detect viral components remains unknown. Our group and others previously identified O-GlcNAc transferase (OGT), an important glucose metabolic enzyme, as a crucial mediator of the antiviral immune responses. Here, by studying a mouse model with a catalytically impaired OGT, we discover a catalytic activity-independent function of OGT in restraining influenza A virus (IAV) infection in addition to its catalytic activity-dependent effect on MAVS-mediated antiviral immunity. Biochemical studies reveal a critical antiviral effect based on OGT interacting with IAV genomic RNA that requires its N-terminal …


Planning And Policy For Safer Roads With Autonomous Vehicles: Moral Decision Making Behavior In Dilemma-Inducing Situations, Fatemeh Nazari, Mohamadhossein Noruzoliaee Aug 2025

Planning And Policy For Safer Roads With Autonomous Vehicles: Moral Decision Making Behavior In Dilemma-Inducing Situations, Fatemeh Nazari, Mohamadhossein Noruzoliaee

Civil Engineering Faculty Publications

This study develops a Dynamic Bayesian Network (DBN) framework to examine how public confidence in autonomous vehicle (AV) safety and willingness-to-ride respond to policy interventions in crash-imminent pedestrian–passenger prioritization scenarios. Using stated preferences survey data from San Francisco (SF) and San Antonio (SA), the model integrates baseline attitudes, socio-demographic factors, and policy conditions to simulate both intra-slice and inter-slice dependencies. Results from empirical-mix simulations indicate that SF respondents, despite having higher baseline confidence and willingness-to-ride, exhibit greater sensitivity to policies prioritizing pedestrians, with significant declines across all scenarios. By contrast, SA respondents show comparatively stable and modestly positive shifts, particularly …


Exploring Neuropsychiatric Manifestations Of Vitamin B Complex Deficiencies, Anamaria Han, Leandro Almeida, Nikhilesh Anand, Ihsan Salloum, Salim Kanaan, Bharathi Gadad, João Paulo Lima Daher Aug 2025

Exploring Neuropsychiatric Manifestations Of Vitamin B Complex Deficiencies, Anamaria Han, Leandro Almeida, Nikhilesh Anand, Ihsan Salloum, Salim Kanaan, Bharathi Gadad, João Paulo Lima Daher

School of Medicine Publications

B complex vitamins, a group of eight water-soluble vitamins, play interconnected roles in maintaining nervous system health. Thiamine (B1), riboflavin (B2), and niacin (B3) are essential as co-enzymes in numerous metabolic reactions related to energy production. Thiamine is involved in the Krebs cycle, riboflavin in the electron transport chain, and niacin plays a key role in both glycolysis and the Krebs cycle. These metabolic processes are vital for sustaining the integrity of the nervous system, as the energy produced is critical for the functioning of nerve cells. Deficiencies in these vitamins can lead to significant neurological and psychiatric conditions, including …


Current Practices In The Study Of Biomolecular Acondensates: A Community Comment, Simon Alberti, Paolo Arosio, Robert B Best, Steven Boeynaems, Danfeng Cai, Rosana Collepardo-Guevara, Gregory L Dignon, Rumiana Dimova, Shana Elbaum-Garfinkle, Nicolas L Fawzi, Monika Fuxreiter, Amy S Gladfelter, Alf Honigmann, Ankur Jain, Jerelle A Joseph, Tuomas P J Knowles, Keren Lasker, Edward A Lemke, Kresten Lindorff-Larsen, Reinhard Lipowsky, Jeetain Mittal, Samrat Mukhopadhyay, Sua Myong, Rohit V Pappu, Karsten Rippe, Tatyana A Shelkovnikova, Anthony G Vecchiarelli, Susanne Wegmann, Huaiying Zhang, Mingjie Zhang, Chloe Zubieta, Markus Zweckstetter, Dorothee Dormann, Tanja Mittag Aug 2025

Current Practices In The Study Of Biomolecular Acondensates: A Community Comment, Simon Alberti, Paolo Arosio, Robert B Best, Steven Boeynaems, Danfeng Cai, Rosana Collepardo-Guevara, Gregory L Dignon, Rumiana Dimova, Shana Elbaum-Garfinkle, Nicolas L Fawzi, Monika Fuxreiter, Amy S Gladfelter, Alf Honigmann, Ankur Jain, Jerelle A Joseph, Tuomas P J Knowles, Keren Lasker, Edward A Lemke, Kresten Lindorff-Larsen, Reinhard Lipowsky, Jeetain Mittal, Samrat Mukhopadhyay, Sua Myong, Rohit V Pappu, Karsten Rippe, Tatyana A Shelkovnikova, Anthony G Vecchiarelli, Susanne Wegmann, Huaiying Zhang, Mingjie Zhang, Chloe Zubieta, Markus Zweckstetter, Dorothee Dormann, Tanja Mittag

Duncan NRI Faculty and Staff Publications

The realization that the cell is abundantly compartmentalized into biomolecular condensates has opened new opportunities for understanding the physics and chemistry underlying many cellular processes, fundamentally changing the study of biology. The term biomolecular condensate refers to non-stoichiometric assemblies that are composed of multiple types of macromolecules in cells, occur through phase transitions, and can be investigated by using concepts from soft matter physics. As such, they are intimately related to aqueous two-phase systems and water-in-water emulsions. Condensates possess tunable emergent properties such as interfaces, interfacial tension, viscoelasticity, network structure, dielectric permittivity, and sometimes interphase pH gradients and electric potentials–. …


Changes In Self-Reported Excessive Daytime Sleepiness Are Associated With 5-Year All-Cause Mortality Risk Among Veterans, Katherine G Bay, Arash Maghsoudi, Amin Ramezani, Drew A Helmer, Amir Sharafkhaneh, Javad Razjouyan Aug 2025

Changes In Self-Reported Excessive Daytime Sleepiness Are Associated With 5-Year All-Cause Mortality Risk Among Veterans, Katherine G Bay, Arash Maghsoudi, Amin Ramezani, Drew A Helmer, Amir Sharafkhaneh, Javad Razjouyan

Faculty, Staff and Students Publications

Excessive daytime sleepiness (EDS) is linked to adverse clinical outcomes. This study evaluated changes in a validated tool to assess EDS, the Epworth Sleepiness Scale (ESS) and mortality risk. This retrospective cohort study included Veterans receiving sleep-related services in the Department of Veterans Affairs (VA) from October 4, 1999 to August 18, 2018, with two qualifying ESS measures. ESS values were extracted from patient notes using a validated natural language processing (NLP) pipeline (96% accuracy). ESS scores were categorised as Normal (0-10) or Abnormal (11-24). Patients were grouped based on ESS changes: Normal-Normal, Normal-Abnormal, Abnormal-Abnormal and Abnormal-Normal. Cox proportional hazards …


Dna Methylation Signatures Of Cardiovascular Health Provide Insights Into Diseases, Madeleine Carbonneau, Yi Li, Yishu Qu, Yinan Zheng, Alexis C Wood, Mengyao Wang, Chunyu Liu, Tianxiao Huan, Roby Joehanes, Xiuqing Guo, Jie Yao, Kent D Taylor, Russell P Tracy, Peter Durda, Yongmei Liu, W Craig Johnson, Wendy S Post, Tom Blackwell, Jerome I Rotter, Stephen S Rich, Susan Redline, Myriam Fornage, Jun Wang, Hongyan Ning, Lifang Hou, Donald Lloyd-Jones, Kendra Ferrier, Yuan-I Min, April P Carson, Laura M Raffield, Alexander Teumer, Hans J Grabe, Henry Völzke, Matthias Nauck, Marcus Dörr, Arce Domingo-Relloso, Amanda Fretts, Maria Tellez-Plaza, Shelley A Cole, Ana Navas-Acien, Meng Wang, Joanne M Murabito, Nancy L Heard-Costa, Brenton Prescott, Vanessa Xanthakis, Dariush Mozaffarian, Daniel Levy, Jiantao Ma Aug 2025

Dna Methylation Signatures Of Cardiovascular Health Provide Insights Into Diseases, Madeleine Carbonneau, Yi Li, Yishu Qu, Yinan Zheng, Alexis C Wood, Mengyao Wang, Chunyu Liu, Tianxiao Huan, Roby Joehanes, Xiuqing Guo, Jie Yao, Kent D Taylor, Russell P Tracy, Peter Durda, Yongmei Liu, W Craig Johnson, Wendy S Post, Tom Blackwell, Jerome I Rotter, Stephen S Rich, Susan Redline, Myriam Fornage, Jun Wang, Hongyan Ning, Lifang Hou, Donald Lloyd-Jones, Kendra Ferrier, Yuan-I Min, April P Carson, Laura M Raffield, Alexander Teumer, Hans J Grabe, Henry Völzke, Matthias Nauck, Marcus Dörr, Arce Domingo-Relloso, Amanda Fretts, Maria Tellez-Plaza, Shelley A Cole, Ana Navas-Acien, Meng Wang, Joanne M Murabito, Nancy L Heard-Costa, Brenton Prescott, Vanessa Xanthakis, Dariush Mozaffarian, Daniel Levy, Jiantao Ma

Faculty, Staff and Students Publications

Background: The association of overall cardiovascular health (CVH) with changes in DNA methylation (DNAm) has not been well characterized.

Methods: We calculated the American Heart Association's Life's Essential 8 score to reflect CVH in 5 cohorts with diverse backgrounds (mean age 54 years, 55% women, and enrollment year ranging from 1989 to 2012). Epigenome-wide association studies (EWAS) for Life's Essential 8 score were conducted, followed by bioinformatic analyses. DNAm loci significantly associated with Life's Essential 8 score were used to calculate a CVH DNAm score. We examined the association of the CVH DNAm score with incident cardiovascular disease (CVD), cardiovascular …


Promising Practices To Address Healthcare Needs Voiced By Local Native Americans, Noelle Taylor, Mykin R. Higbee, Raiden Gaul Aug 2025

Promising Practices To Address Healthcare Needs Voiced By Local Native Americans, Noelle Taylor, Mykin R. Higbee, Raiden Gaul

Transforming Communities

Purpose

To examine barriers and facilitators to nursing education among Native Americans and identify evidence-based strategies to increase the number of Native American nurses working in their local communities to address health disparities.

Background

Native Americans experience significantly higher rates of chronic illnesses such as diabetes and heart disease, and lower life expectancies. Only 4% of registered nurses identify as Native American, with no growth despite increased funding for diversity in nursing education. This underrepresentation contributes to culturally insensitive care and persistent healthcare inequities stemming from historical marginalization and trauma.

Methods

A comprehensive literature review was conducted using CINAHL, PubMed, …