Digital Commons Network^™

Kegamangan Sistem Perlindungan Dan Pengelolaan Lingkungan: Melihat Uu Ciptaker Dari Perspektif Prinsip Non-Regresi, Andri G. Wibisana

Jurnal Hukum & Pembangunan

This article evaluates the Environmental Protection and Management Law (UUPPLH) as amended by the Omnibus Law on Job Creation (UUPPLH-Ciptaker) and its implementing regulations. The evaluation uses the normative framework of the principle of non-regression to assess whether the provisions of the UUPPLH-Ciptaker and its implementing regulations represent a setback compared to the legal conditions prior to the enactment of the Omnibus Law. This paper argues that the changes introduced by the UUPPLH-Ciptaker indicate several regressions in Indonesia’s environmental law, particularly in the following areas: a) the weakening of provisions on Environmental Impact Assessment (AMDAL) and Environmental Management and Monitoring …

Exact And Approximate Conformal Inference For Multi-Output Regression, Chancellor Johnstone, Eugene Ndiaye

Faculty Publications

It is common in machine learning to estimate a response y given covariate information x . However, these predictions alone do not quantify any uncertainty associated with said predictions. One way to overcome this deficiency is with conformal inference methods, which construct a set containing the unobserved response with a prescribed probability. Unfortunately, even with a one-dimensional response, conformal inference is computationally expensive despite recent encouraging advances. In this paper, we explore multi-output regression, delivering exact derivations of conformal inference p-values when the predictive model can be described as a linear function of y . Additionally, we introduce a multivariate …

Stakeholder Views On Lessons Learned For The Antimicrobial Resistance Panel From Previous International Science Panels [Version 1], Iruka N. Okeke, Ayodele A. Akinyele, Javier Guzman, Kevin Outterson

Faculty Scholarship

The United Nations General Assembly called in September 2024 for the establishment of an independent panel for actionable evidence against antimicrobial resistance (IPEA). The task of designing the panel was given to the Quadripartite Joint Secretariat (QJS) on Antimicrobial Resistance (AMR) with a delivery timeline of 15 months. To promote stakeholder thought and input around what this panel should look like and how it should work, which could feed into the QJS’s consultation process, we independently commissioned seven papers to examine lessons that could be learned from other high-level scientific panels. We then called a convening of stakeholders that were …

Experiences And Perspectives Of Sexual And Reproductive Health Among Women In Recovery From Opioid Use Disorder, Nicole M. Mattson, Aleigha Barry, Jessica L. Zemlak

College of Nursing Faculty Research and Publications

Background

Women in recovery from opioid use disorder (OUD) have unmet sexual and reproductive health (SRH) needs resulting in health disparities such as unintended pregnancy and sexually transmitted infections/HIV infection compared with women without OUD. The purpose of this qualitative descriptive study was to explore the perceptions and experiences of co-occurring multiple social-ecologic influences (individual, interpersonal, community, society) on SRH among women in recovery from OUD.

Methods

Purposive sampling was used to recruit cis-gender women aged 18–49 who self-identify as being in recovery from OUD and speak English. We conducted one 45- to 60-minute audio-recorded semistructured telephone interview with each …

Multiyear Implementation And Qualitative Evaluation Of A Peer Mentoring Circle Program, Tana M. Karenke, Juanita T. Garcia, Alexandria Zielinski

College of Nursing Faculty Research and Publications

Background

Students from disadvantaged backgrounds often experience intensified challenges, including life stressors, social isolation, discomfort relating to the dominant culture on campus, and under-preparation if coming from low-resource high schools and neighborhoods. Multiyear implementation and outcomes of an ongoing peer mentoring circle (PMC) program for undergraduate nursing students from disadvantaged and underrepresented minority backgrounds are described.

Method

This study examined a 5-year longitudinal descriptive evaluation of ongoing PMC programming using thematic analysis.

Results

Four major themes were identified from student qualitative evaluation data: (a) connection and friendship; (b) adjustment and transition; (c) academic support; and (d) leadership skills. Challenges encountered …

A “Re-Imagining The Economic Value Of Nursing” Summit Summary And Recommendations, Olga Yakusheva, Marianne E. Weiss, Tanya Mulvey, Anabel F. Castillo, Marcela Campoli

College of Nursing Faculty Research and Publications

In April 2024, the ANA Enterprise sponsored a “Re-imagining the Economic Value of Nursing” Summit to move the conversation forward on recognizing and leveraging the economic value of nursing within organizations across the US healthcare system. Invited participants engaged in a spirited dialogue about reconceptualizing nurses as critical assets in generating value within the production and financial dynamics of contemporary healthcare systems. This article summarizes the discussion and recommendations emerging from the summit.

In healthcare organizations and systems, nurse executives are the bridge between the production of patient care by the nursing workforce and the organizational financial performance. Historically, nursing …

Botulinum Neurotoxin Light Chain/A1 Uses Fast Synaptic Vesicle Cycling To Cleave Plasma Membrane Bound Snap-25, Alexander Gardner, Molly Sneller, William H. Tepp, Joseph T. Barbieri, Sabine Pellett

College of Nursing Faculty Research and Publications

Botulinum neurotoxins (BoNT) are the most potent protein toxins for humans, yet how BoNT-Light Chain/A1 (LC/A1) journeys to cleave intracellular SNAP-25 is understudied. Here we use a cell-based assay to measure cytosolic EGFP-LC/A1 intracellular trafficking and SNAP-25 cleavage in Neuro-2A cells. Intracellular LC/A1 associated on microtubules and co-localized with Rab GTPases involved in fast synaptic vesicles and endosome recycling. Multiple Dominant Negative (DN) Rabs GTPases involved in fast synaptic vesicles or endosome recycling inhibited LC/A1 trafficking to the intracellular plasma membrane and SNAP-25 cleavage. A cytosolic LC/A1 variant that bound the plasma membrane from the cytosol was insensitive to DNRab …

Designing An Electronic Patient-Reported Outcomes Information Infrastructure Supported By The Re-Aim Implementation Framework, Amy C Moreno, Angela Peek, Toshiko S Stein, Kevin R Shook, Sara M Ali, Laia Humbert-Vidan, Aileen Chen, Miriam Lango, Anna Lee, Michael Spiotto, William H Morrison, Adam S Garden, Jack Phan, Steven J Frank, Katherine Hutcheson, David I Rosenthal, Clifton D Fuller, G Brandon Gunn

Faculty, Staff and Student Publications

Objective: Patient-reported outcomes (PROs) contain valuable information that can be leveraged by providers to perform timely interventions and improve quality of life and survival. However, the implementation of electronic PROs (ePROs) remains a challenge from technical and evaluation perspectives. Our objective was to construct a robust electronic health record (EHR)-integrated ePRO information infrastructure founded on RE-AIM (reach-effectiveness-adoption-implementation-maintenance) principles.

Materials and methods: We used Epic Systems as our EHR platform to build the MD Anderson Symptom Index Head and Neck Module (MDASI-HN) for release to all patients undergoing evaluation and/or treatment in our HN Radiation Oncology clinics. RE-AIM metrics were established …

Walking Interventions And Cognitive Health In Older Adults: A Systematic Review Of Randomized Controlled Trials, Jongwon Lee, Delia West, Christine Pellegrini, Jingkai Wei, Sara Wilcox, Jean Neils-Strunjas, A Caroline Rudisill, Daniela B Friedman, David X Marquez, Jenna Dzwierzynski, Joyce Balls-Berry, Rachelle Gajadhar, Chih-Hsiang Yang

2020-Current year OA Pubs

ObjectiveThis systematic review summarizes the effectiveness and the dose of walking interventions on specific cognition domains in older adults, including executive function, memory, attention, processing speed, and global cognition.Data sourcePublished randomized controlled trials in PubMed, Embase, and Web of Science until 10 May 2023.Study Inclusion and Exclusion CriteriaStudies include older adults without Alzheimer's or related dementias, involving a walking intervention and performance-based neuropsychological assessments for executive function, memory, processing speed, attention, or global cognition.Data ExtractionTwo independent research assistants reviewed 8424 studies and included 17 studies.Data SynthesisParticipant demographics, intervention features (type, intensity, time, frequency, duration, format, and context), cognitive assessment tools, …

Spatial Colocalization And Molecular Crosstalk Of Myofibroblastic Cafs And Tumor Cells Shape Lymph Node Metastasis In Oral Squamous Cell Carcinoma, Ken Furudate, Shuya Kasai, Tadashi Yoshizawa, Yuya Sasaki, Kohei Fujikura, Shintaro Goto, Ryohei Ito, Koki Takagi, Tomoyuki Tanaka, Hiroshi Kijima, Kosei Kubota, Ken Itoh, Wataru Kobayashi, Koichi Takahashi

Faculty, Staff and Student Publications

Lymph node metastasis (LNM) is a critical prognostic factor for patients with oral squamous cell carcinoma (OSCC). Previous research has implicated the partial epithelial-to-mesenchymal transition of tumor cells and myofibroblastic cancer-associated fibroblasts (myCAFs) in the LNM process. However, the underlying molecular mechanisms remain poorly understood. Here, we conducted a comprehensive molecular analysis integrating original and publicly available OSCC data from bulk genome and transcriptome, single-cell transcriptome, and spatial transcriptome analyses. We found that myCAFs were quantitatively and functionally activated in LNM-positive samples and spatially colocalized with OSCC cells within the invasive tumor front (ITF), providing a niche that may facilitate …

Categorial Declinations & Democracy, Brenner M. Fissell

Faculty Publications

The most contentious action taken by reform prosecutors has been the issuance of categorical declination policies. Opponents decry this as bureaucratic nullification of democratically enacted offenses, while the prosecutors themselves counter that they are responding to the will of their local electorate. Democracy claims, it appears, have taken center stage in this debate, and they are deployed by both sides. How should we think about democracy and categorical declinations? The most comprehensive scholarly work on this subject is a 2021 article by Professor Kerrel Murray. In this essay, I hope to continue the work begun by Murray, offering additional insights …

Blending Informing Literacy And Visual Literacy: Instructional Vignettes In Art, Architecture, And Design, Stephanie Beene, Sara Schumacher, Dana Statton Thompson, Mary Wegmann

University Libraries & Learning Sciences Faculty and Staff Publications

The ACRL Framework for Visual Literacy in Higher Education (Framework for Visual Literacy), based on empirical research into the trends, opportunities, and challenges facing the field of visual literacy in the twenty-first century,1 was codified in April 2022 and is an adaptable document to help learners grow their visual literacy competencies. In this chapter, written by four of the task force members charged with the creation of the Framework for Visual Literacy, we examine the relationship between the four themes in the Framework for Visual Literacy and the six frames of the ACRL Framework for Information Literacy for Higher Education …

Launching! To Adulthood, A Culturally Adapted Treatment Program For Military-Dependent Autistic Young Adults And Their Military Parents: A Pilot Study, Antonio F Pagán, Jordan Kenemore, Maj Mark Ahlenius, Linda Hernandez, Stephen Armstrong, Katherine A Loveland, Ron Acierno

Faculty, Staff and Student Publications

Introduction: Military-dependent young adults (17-25 years old) with autism spectrum disorder (ASD) face significant barriers to accessing services during their transition to adulthood. Frequent relocations, disrupted care, and limited ASD-tailored interventions exacerbate the challenges for these families, with many young adults experiencing a "service cliff" as they age out of pediatric care and school-based services. Addressing these gaps is critical, particularly given the rising mental health challenges and executive dysfunction in this population. This study evaluates the preliminary efficacy of an adapted telehealth intervention, the Military-Launching! program, designed to support young adults with ASD and their military families.

Materials and …

¡Iniciando! La Adultez (Launching! To Adulthood): A Cultural And Linguistic Adaptation Of A Group Therapy Program For Young Adults With Autism Spectrum Disorder Transitioning To Adulthood, Antonio F Pagán, Katherine A Loveland, Ron Acierno

Faculty, Staff and Student Publications

Objectives: The transition to adulthood is a formative period of development for young adults with autism spectrum disorder (ASD), as they work towards independence and managing adult responsibilities. While evidence-based interventions have been developed for young adults with ASD, they have rarely been culturally and linguistically adapted for the Latino, Spanish-speaking community. The present study provided initial feasibility and acceptability data for a therapy program for Latino young adults with ASD transitioning to adulthood and their Spanish-speaking parents.

Methods: The culturally adapted and translated intervention, called ¡Iniciando! la Adultez, is a 10-week therapy program based on an evidence-based treatment ( …

Evaluation Of A Theoretical And Experiential Training Programme For Allied Healthcare Providers To Prescribe Exercise Among Persons With Multiple Sclerosis: A Co-Designed Effectiveness-Implementation Study, Yvonne C. Learmonth, Georgios Mavropalias, Kym Wansbrough

Research outputs 2022 to 2026

Background: Multiple sclerosis (MS) is the most prevalent neurological disorder in young adults, characterised by physical, psychological and cognitive dysfunction. Exercise training is a safe management strategy. Healthcare providers (HCPs) acknowledge deficiencies in awareness, counselling strategies, and resources that prevent them from promoting and prescribing this effective treatment. We implemented an online evidence-based educational programme and evaluated the effect, acceptability, appropriateness, and feasibility of the programme in improving HCP confidence, knowledge, and attitudes towards remote exercise prescription to persons with MS. Methods: Physiotherapists and exercise physiologists were recruited and received the educational programme (online theory and 16-week experience of prescribing …

The Luminos Project: Co-Designing A Short-Stay Suicide Support Model For Young People, Aims Hansen, Samantha Speirs, Kirsten Panton, Jacinta Freeman, Zrinka Highfield, Kieren Marshall, Eleanor Tighe, Laura Hemming, Bep Uink, Francis Mitrou, Vu Vuong, Ashleigh Lin

Research outputs 2022 to 2026

Background: Suicide was the leading cause of death among young Australians aged 15–24 years old in 2023, with 392 lives lost. The continued high numbers of youth suicide demand urgent exploration of alternative approaches to suicide intervention in this population. The United Kingdom-based suicide service Maytree offers an innovative short-term stay for people experiencing suicidal thoughts. Grounded by the Maytree model-of-care, the aim of the current study was to co-design a short-stay service responsive to the specific needs of suicidal young people. Methods: Semi-structured and focus group interviews with young people (n = 38), caregivers (n = 11) and key …

Old Frames On New Media: Health Misinformation In Black Digital Communities, Merriah Croston

Brown School Graduate Student Theses and Dissertations

Growing evidence suggests that health misinformation has the potential to proliferate on social media. However, our understanding of the problem’s magnitude continues to evolve. Despite several studies on health misinformation and Black communities in the United States (U.S.), few of these studies characterize misinformation within digital settings. This dissertation seeks to address this gap by: 1) synthesizing the literature on health misinformation and Black communities to identify prevalent misinformation topics and claims, characteristics of exposure to and belief in these topics and claims, and successful intervention strategies; 2) quantifying and characterizing the volume of COVID-19 misinformation on Black Twitter during …

Society Of Vascular And Interventional Neurology (Svin) Stroke Interventional Laboratory Consensus (Silc) Criteria For Training Standards And Maintenance Of Certification In Neurointervention, Ossama Y. Mansour, Kaiz S. Asif, Roberta Novakovic-White, Boris Pabon, Santiago Ortega-Gutierrez, Atilla Ozcan Ozdemar, Alicia Castonguay, Brijesh Mehta, Dileep R. Yavagal, Ameer E. Hassan

School of Medicine Publications

The global shortage of neurointerventionalists presents a challenge to timely stroke care, particularly in low‐ and middle‐income countries. The Society of Vascular and Interventional Neurology Stroke Interventional Laboratory Consensus criteria aim to standardize training and certification in neurointervention to address these disparities. This white paper reviews existing training standards in various regions, identifies gaps, and proposes a structured framework encompassing entry requirements, program structure, and certification processes. The Stroke Interventional Laboratory Consensus criteria further outline requirements for training centers and program directors. By establishing global standards, the Stroke Interventional Laboratory Consensus criteria seek to improve patient outcomes and expand access …

Challenges And Opportunities In Reducing Risk Of Diabetes-Related Cardiovascular Disease: Making Every Contact Count, Michelle Clapham

School of Nursing and Midwifery

Despite recent Government initiatives to reduce rates, the prevalence of type 2 diabetes isexpected to continue rising to almost 10% of the population by 2035. Complications of type 2diabetes, such as cardiovascular disease (CVD), contribute to approximately 22 000 deathsannually in England, indicating a need for population health management through preventativehealthcare. The Making Every Contact Count (MECC) initiative recommends the building ofpreventative strategies into routine primary care appointments to reduce modifiable risk factorsassociated with both type 2 diabetes and CVD. This article explores the unique opportunitiesgeneral practice nurses have to promote primary and secondary prevention of CVD.

Habit And The Potential For Actor Training With Immersive And Virtual Production Technology, John Matthews

School of Art, Design and Architecture

The advance of immersive and virtual technologies draws into starker contrast the analogue modalities of dominant approaches to actor training and makes more visible certain of their dynamics, which are analysed here using a philosophical framework of habit and habitus as propositionally causative. This technology is disruptive to habit and habitus in actor training and signifies potential to experiment with these dynamics to address extant problems in actor training. Problems in training habitus discussed here derive from trainers’ habits but arise primarily for trainees, and especially so for certain groups. I use Lazlo Pearlman and Deirdre McLaughlin’s critique of the …

Embedding Graduate Attributes Through Learning Experiences, Shaun Ferns, Barry J. Ryan, Fionnuala Darby

Reports

This guide outlines TU Dublin’s approach to embedding the University’s Graduate Attributes; People, Planet, and Partnership, through intentional curriculum design aligned with the Framework of Learning Experiences (FLE). The guide demonstrates how these experiential threads intersect with major international and European competency frameworks, including GreenComp, EntreComp, DigComp, , UDL, and EDIT, enabling programme teams to meet multiple standards through coherent learning design. This document reinforces TU Dublin’s commitment to a learner-centred, practice-based curriculum that develops capable, ethical, and future-focused graduates.

Neurologists' Perspectives On Sudep Communication: A Comparative Study Across Five European Countries, Rohit Shankar

Peninsula Medical School

Objectives: The leading cause of epilepsy mortality is Sudden unexpected death in epilepsy (SUDEP). National and international guidelines recommend that people with epilepsy are counseled on SUDEP risk at the point of diagnosis or at the earliest opportunity. This study compares neurologist views from five European countries on attitudes and relevance of SUDEP communication. Methods: A cross-sectional online survey of 17 Likert questions using validated themes was circulated via different ILAE and/or equivalent organizations using a non-discriminatory exponential snowballing technique, leading to a non-probability sampling. Data were analyzed using descriptive statistics, Kruskal–Wallis, Chi-square, and Fisher's exact tests. Significance was accepted …

The Immeasurable Value Of Plankton To Humanity, Maria Grigoratou, Susanne Menden-Deuer, Abigail Mcquatters-Gollop, George Arhonditsis, Luis Felipe Artigas, Sakina-Dorothée Ayata, Dalida Bedikoğlu, Beatrix E Beisner, Bingzhang Chen, Claire Davies, Lillian Diarra, Owoyemi W Elegbeleye, Jason D Everett, Tatiane M Garcia, Wendy C Gentleman, Rodrigo Javier Gonçalves, Tamar Guy-Haim, Svenja Halfter, Jana Hinners, Richard R Horaeb, Jenny A Huggett, Catherine L Johnson, Maria T Kavanaugh, Ana Lara-Lopez, Christian Lindemann, Celeste López-Abbate, Monique Messié, Klas Ove Möller, Enrique Montes, Frank E Muller-Karger

School of Biological and Marine Sciences

Plankton, a diverse group of aquatic organisms, make Earth livable, regulate aquatic life, and provide benefits to human societies such as access to clean water, food security, and well-being. They also support economies and inspire biotechnological innovations. This article aims to raise awareness of the value of plankton to humanity and serves as an informative guide for aquatic professionals, policymakers, and anyone interested in plankton. We present the value of plankton across six themes of human interest: biogeochemistry; ecology; climate; the evolution of science; economy; and culture, recreation, and well-being. Guided by the 2022 Intergovernmental Science-Policy Platform on Biodiversity and …

Privacy-Preserving Ridge Regression Over Encrypted Data Under Multiple Keys, Yanling Li, Junzuo Lai, Meng Sun, Beibei Song, Robert H. Deng

Research Collection School Of Computing and Information Systems

With the increase of private data being collected by data owners, it has been a trend for data owners to store the data on cloud computing platforms. The huge amounts of data in cloud servers bring fresh development opportunities to machine learning, which is applied to build a high-quality machine learning model based on a large training dataset. However, to ensure the privacy of data and facilitate retrieval, data owners often upload encrypted data under their public keys. But it creates new challenges for machine learning to learn a predictive model over these encrypted data under different keys. Most existing …

Map As A By-Product: Collective Landmark Mapping From Imu Data And User-Provided Texts In Situated Tasks, Ryo Yonetani, Kotaro Hara

Research Collection School Of Computing and Information Systems

This paper presents Collective Landmark Mapper, a novel map-as-a-by-product system for generating semantic landmark maps of indoor environments. Consider users engaged in situated tasks that require them to navigate these environments and regularly take notes on their smartphones. Collective Landmark Mapper exploits the smartphone's IMU data and the user's free text input during these tasks to identify a set of landmarks encountered by the user. The identified landmarks are then aggregated across multiple users to generate a unified map representing the positions and semantic information of all landmarks. In developing the proposed system, we focused specifically on retail applications and …

Towards Multimodal Emotional Support Conversation Systems, Yuqi Chu, Lizi Liao, Zhiyuan Zhou, Chong-Wah Ngo, Richang Hong

Research Collection School Of Computing and Information Systems

The integration of conversational artificial intelligence (AI) into mental health care promises a new horizon for therapist-client interactions, aiming to closely emulate the depth and nuance of human conversations. Despite the potential, the current landscape of conversational AI is markedly limited by its reliance on single-modal data, constraining the systems’ ability to empathize and provide effective emotional support. This limitation stems from a paucity of resources that encapsulate the multimodal nature of human communication essential for therapeutic counseling. To address this gap, we introduce the Multimodal Emotional Support Conversation (MESC) dataset, a first-of-its-kind resource enriched with comprehensive annotations across text, …

Finding Safety Violations Of Ai-Enabled Control Systems Through The Lens Of Synthesized Proxy Programs, Jieke Shi, Zhou Yang, Junda He, Bowen Xu, Dongsun Kim, Donggyun Han, David Lo

Research Collection School Of Computing and Information Systems

Given the increasing adoption of modern AI-enabled control systems, ensuring their safety and reliability has become a critical task in software testing. One prevalent approach to testing control systems is falsification, which aims to find an input signal that causes the control system to violate a formal safety specification using optimization algorithms. However, applying falsification to AI-enabled control systems poses two significant challenges: (1) it requires the system to execute numerous candidate test inputs, which can be time-consuming, particularly for systems with AI models that have many parameters, and (2) multiple safety requirements are typically defined as a conjunctive specification, …

History Informing The Future Of Exercise Oncology, Daniel A. Galvão, Kerry S. Courneya, Alejandro Lucia, Anne M. May, Karen Mustian, Allison B. Warner, Wiskemann Joachim, Karen Wonders, Kathryn H. Schmitz, Robert U. Newton

Research outputs 2022 to 2026

Exercise is increasingly recognized by patients, clinicians, and allied health professionals globally as an important component of cancer care. In this paper, we provide a viewpoint on developments in exercise oncology over the past 4 decades leading up to the creation of the International Society of Exercise Oncology (ISEO). We briefly review research in adult and pediatric cancers from early foundation studies to larger randomized controlled trials published in mainstream oncology journals alongside critical work undertaken in exercise and cancer biological mechanisms. We also discuss potential strengths, weaknesses, opportunities, and threats facing ISEO in becoming a global forum for exercise …

Closing The Youth Activity Gap Through School District–Community Partnerships, Joseph Anthes

Journal of Youth Development

A growing divide in physical activity amongst youth, fueled by the privatization of youth athletic programs, most negatively impacts underrepresented students. Intramural-sports programs hold the potential to engage more of our youth in physical activity, including those from marginalized populations. Utilizing a collective impact approach, school-community partnerships can create opportunities for access and strive toward equity in youth health. This study evaluates a partnership between a school district and a regional health care provider that resulted in the creation of a youth intramural-sports program by describing the partnership’s implementation strategies and by comparing first year enrollment data. Implementation strategies include: …

Full Issue, Volume 20, Issue 3

Journal of Youth Development

No abstract provided.